The purpose of this research study is to evaluate a new screening procedure for the early detection and monitoring of Age-related Macular Degeneration (AMD) in community settings and community hospital settings, to identify associated risk factors, and develop personalized monitoring strategies for at-risk individuals throughout the 5 years follow up period, which will allow us to establish prevalence, natural history of progression of early AMD in the community.
Eligibility
Sex
ALL
Min age
55 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Adults aged 55 years or older
* No severe systemic illnesses that prevent study participation
* Willing and able to undergo protocol-required procedures for both eyes
* Willing and able to provide written informed consent
Exclusion Criteria:
* Systemic disorders that preclude reliable clinical examination or multimodal imaging
* Poor compliance or severe mental illness that hinders participation
* Persons who are unable to give informed consent
Primary outcome measure(s)
To establish the natural history of AMD in Asian elderly and to identify clinical multimodal imaging, genetic, and metabolomic predictors of progression. — 3 years Progression is defined as the change from early signs of AMD to advanced AMD.
Trial sites (2)
Facility
City
Region
Status
Outram Community Hospital
Singapore
Singapore
Recruiting
Singapore National Eye Centre/ Singapore Eye Research Institute
Singapore
Singapore
Recruiting
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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