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Clinical Trials in Singapore / NCT07205133
Recruiting Not applicable

A Randomized Controlled Trial Comparing Whole Body Vibration Therapy With Usual Care and Usual Care to Improve Muscle Health in Older Adults

NCT07205133 · tracked via the Priya Life Science Singapore tracker
Phase
Not applicable
Started
2026-01-10
Last updated
2026-04-15

Condition(s) studied

AgingFrailtySarcopeniaMuscle StrengthMuscle FunctionMuscle Mass

Investigational drug(s) / intervention(s)

Whole Body Vibration TrainingOtago Exercise

Whole Body Vibration Training: Information already included in arm/group descriptions.

Otago Exercise: Usual Care

Study summary

This study is a randomized controlled trial where participants would be randomly assigned to one of 2 groups. One group would receive Whole body vibration therapy and usual care and the other group only usual care. Measurements of muscle mass, strength and function would be taken before the interventions, and at 2 other points after interventions. Differences in the outcomes between the two groups would be analysed.

Eligibility

Sex
ALL
Min age
65 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Healthy Volunteer or Patients aged 65 and above, * Clinical frailty Scale (CFS) score of 3-4, * Independently ambulating without any aid * willingness and consent to participate in the study and ability to travel to the study-site for the measurements and interventions, and * participants with no regular exercise habits (defined as less than 150mins/week of moderate intensity aerobic exercise and less than twice a week of strengthening exercises)for past 3 months. Exclusion Criteria: * current active enrolment into any Day Rehab or community exercise program, * contraindications to WBVT machine usage (see below), * diagnosis of dementia, * history of Diabetes Mellitus * BMI ≤20kg/m2, * recent hospital admissions within the last 3 months, * end stage organ failure, * chronic diseases which are not well managed, for example, poorly controlled hypertension, * New York Heart Association (NYHA) score II and above for patients with history of heart failure and * MUST Score ≥1. Contraindications to WBVT: PRIMARY CONTRAINDICATIONS TO WBVT * Pregnancy * Acute thrombosis (acute vascular occlusion) * Artificial joints in stimulated body regions * Fresh fractures in stimulated body regions * Within 3 months post surgery/procedure and/or any fresh wounds and scars in the stimulated body regions * or if the wound healing is not yet completely finished. SECONDARY CONTRAINDICATIONS TO WBVT * Acute inflammation of the musculoskeletal system, activated arthrosis or * arthropathy (e.g. acute inflammation and swelling in joints). * Acute tendinopathies in stimulated body regions (acute tendonitis) * Acute hernias (tissue ruptures) * Acute discopathy (acute disc-related back problem) * Stone disease of the bile ducts and urinary tract * Rheumatoid Arthritis * Epilepsy due to secondary risk of injury

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Changi General Hospital Singapore Singapore Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07205133 on ClinicalTrials.gov ↗ ← All trials in Singapore