AgingFrailtySarcopeniaMuscle StrengthMuscle FunctionMuscle Mass
Investigational drug(s) / intervention(s)
Whole Body Vibration TrainingOtago Exercise
Whole Body Vibration Training: Information already included in arm/group descriptions.
Otago Exercise: Usual Care
Study summary
This study is a randomized controlled trial where participants would be randomly assigned to one of 2 groups. One group would receive Whole body vibration therapy and usual care and the other group only usual care. Measurements of muscle mass, strength and function would be taken before the interventions, and at 2 other points after interventions. Differences in the outcomes between the two groups would be analysed.
Eligibility
Sex
ALL
Min age
65 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Healthy Volunteer or Patients aged 65 and above,
* Clinical frailty Scale (CFS) score of 3-4,
* Independently ambulating without any aid
* willingness and consent to participate in the study and ability to travel to the study-site for the measurements and interventions, and
* participants with no regular exercise habits (defined as less than 150mins/week of moderate intensity aerobic exercise and less than twice a week of strengthening exercises)for past 3 months.
Exclusion Criteria:
* current active enrolment into any Day Rehab or community exercise program,
* contraindications to WBVT machine usage (see below),
* diagnosis of dementia,
* history of Diabetes Mellitus
* BMI ≤20kg/m2,
* recent hospital admissions within the last 3 months,
* end stage organ failure,
* chronic diseases which are not well managed, for example, poorly controlled hypertension,
* New York Heart Association (NYHA) score II and above for patients with history of heart failure and
* MUST Score ≥1.
Contraindications to WBVT:
PRIMARY CONTRAINDICATIONS TO WBVT
* Pregnancy
* Acute thrombosis (acute vascular occlusion)
* Artificial joints in stimulated body regions
* Fresh fractures in stimulated body regions
* Within 3 months post surgery/procedure and/or any fresh wounds and scars in the stimulated body regions
* or if the wound healing is not yet completely finished.
SECONDARY CONTRAINDICATIONS TO WBVT
* Acute inflammation of the musculoskeletal system, activated arthrosis or
* arthropathy (e.g. acute inflammation and swelling in joints).
* Acute tendinopathies in stimulated body regions (acute tendonitis)
* Acute hernias (tissue ruptures)
* Acute discopathy (acute disc-related back problem)
* Stone disease of the bile ducts and urinary tract
* Rheumatoid Arthritis
* Epilepsy due to secondary risk of injury
Primary outcome measure(s)
Isometric Knee Extension Strength — Baseline and 2 weeks after intervention and 3 months after intervention Measured using a JTech Medical, Northstar Echo Muscle Tester with subject seated with knee flexed at 90 degrees and hanging, muscle tester is placed at the ventral surface of the ankle between malleoli and subject instructed to push against tester with maximal effort to extend the knee. Best of three trials would be taken.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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