🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Contributor sign in
Latest
Clinical Trials in Singapore / NCT06812130
Recruiting Observational

Surviving the Pediatric Intensive Care Unit (PICU)

NCT06812130 · tracked via the Priya Life Science Singapore tracker
Sponsor
KK Women's and Children's Hospital
Phase
Observational
Started
2025-02-11
Last updated
2026-05-05

Condition(s) studied

Post Intensive Care Syndrome (PICS)

Investigational drug(s) / intervention(s)

This is a non-interventional study.

This is a non-interventional study.: This is a non-interventional study.

Study summary

Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness. However, PICU survivors are at risk of long-term health sequalae. Given the increased recognition of physical, cognitive, and psychological sequelae in PICU survivors, the concept of post-intensive care syndrome-pediatrics (PICS-p) has been proposed. Besides the PICU patient/survivor, the PICS-p framework also highlights the impacts of a child's critical illness has on the family. The impact of a PICU admission extends beyond the patient and parents, potentially affecting healthy siblings who are navigating their own developmental challenges. Healthy siblings may face emotional distress, increased responsibilities, and disruptions in their daily routines, all of which can contribute to long-term negative outcomes if unaddressed. Thus, this study consists of two cohorts to understand the long-term physical, cognitive, and psychological outcomes in PICU survivors and their families, and the short-term impacts on siblings of critically ill children.

Eligibility

Sex
ALL
Min age
28 Days
Max age
16 Years
Healthy volunteers
No
Inclusion Criteria: \[HOPE Cohort\] 1. Between 28 days - 16 years of age at PICU admission 2. Have an expected PICU stay \> 48 hours\* \[SHACK-S Cohort\] 1. Healthy children (aged 4 -16 years old) with critically ill sibling between 28 days - 16 years of age at PICU admission 2. Has a critically ill sibling who has an expected PICU stay \> 48 hours 3. Lives in the same household as the critically ill sibling and parents prior to admission Exclusion Criteria: \[HOPE Cohort\] 1. Do-Not-Resuscitate status 2. Lack of informed consent 3. Prior enrolment in this study \[SHACK-S Cohort\] 1. Children of critically ill sibling with Do-Not-Resuscitate status 2. Children with condition listed on paediatric Complex Chronic Conditions (CCC) system Version 3.0 or with neurocognitive/neurodevelopmental delays or disorders 3. Previous admission to PICU 4. Lack of informed consent 5. Prior enrolment in this study * Note: For participating study sites without a dedicated PICU (e.g., sites where patients are managed in a combined ward under High Dependency (HD) or ICU status), PICU stay will be defined as the duration during which the patient is assigned an ICU status. The determination of ICU status will be made at the discretion of the respective site's study team and Site-PI.

Primary outcome measure(s)

Trial sites (2)

FacilityCityRegionStatus
National University Singapore Singapore Singapore Recruiting
KK Women's and Children's Hospital Singapore Singapore Recruiting

More KK Women's and Children's Hospital trials in Singapore

Pain Detection Through Automated Video Analysis Active, not recruiting
Group Drumming for Improving the Health of Community-Dwelling Elderly Active, not recruiting
Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS) Active, not recruiting
Integrating Community LITE Programme as an Online Family-based Intervention to Combat Childhood Obesity Recruiting
Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06812130 on ClinicalTrials.gov ↗ ← All trials in Singapore