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Clinical Trials in Singapore / NCT07545590
Active, not recruiting Phase 1

A Study of Eltrekibart (LY3041658) in Healthy Participants

NCT07545590 · tracked via the Priya Life Science Singapore tracker
Phase
Phase 1
Started
2026-04-21
Last updated
2026-09-18

Condition(s) studied

Healthy

Investigational drug(s) / intervention(s)

LY3041658 →LY3041658 →

LY3041658: Administered SC

LY3041658: Administered IV

Study summary

The main purpose of this study is to evaluate how eltrekibart is absorbed by the body when it is given under the skin to healthy participants.

The study will last about 17 weeks.

Eligibility

Sex
ALL
Min age
21 Years
Max age
65 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Are overtly healthy as determined by medical evaluation including medical history and physical examination * Have a minimum body weight of 45 kilograms (kg). * Have a body mass index (BMI) within the range of 18.5 to 28.5 kilograms per square meter (kg/m²), inclusive Exclusion Criteria: * Have multiple severe allergies to prescription or nonprescription drugs * Are immunocompromised * Have had any of the following types of infection within 3 months prior to the screening visit: * Serious, that is, requiring hospitalization, or intravenous or equivalent oral antibiotic treatment * Opportunistic infections Note: Herpes zoster is considered active and ongoing until all vesicles are dry and crusted over * Chronic, that is, duration of symptoms, signs, or treatment of 6 weeks or longer, or * Recurring, including, but not limited to: * herpes simplex, * herpes zoster, * recurring cellulitis, or * chronic osteomyelitis. * Are currently pregnant or are intending to become pregnant or to breastfeed at any time in the study or within 16 weeks after receiving the single dose of study intervention.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Lilly Centre for Clinical Pharmacology Singapore Singapore

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07545590 on ClinicalTrials.gov ↗ ← All trials in Singapore