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Trackers› Clinical trials› Rome
Clinical trial register · Italy

Clinical Trials in Rome, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Italy and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6791 matching records held by the registry are in this view. Synced 11 Oct 2026, 03:19 UTC
6791
Studies in scope
all four open statuses
4079
Recruiting now
open to new participants
1019
Lead sponsors
across recruiting studies
Top sites
Milan 2846 Bologna 1303 Roma 1272 Naples 983 Rome 968
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS171 Hoffmann-La Roche73 AbbVie56 Merck Sharp & Dohme LLC40 Sanofi30
Site location
Milan2846 Bologna1303 Roma1272 Naples983 Rome968
All 489 locations
Target enrolment
to

Trials with a site in Rome

968 of 6791 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Italy
Start
Not yet open
Alexion Pharmaceuticals, Inc.
Phase 3
1,180
Bologna, Forlì, Florence, Rome, Messina, Naples, Padova, Pisa
2027-11-23
Not yet open
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 3
92
Rome, Milan, Pisa
2027-02-03
Not yet open
AI-Assisted 3D Reconstruction for Lung Resection Planning
NCT07853157Lung Cancer, Artifical Intelligence, Surgery for Primary Lung Cancer
S. Andrea Hospital
Observational
50
Rome
2026-11-02
Not yet open
Non-Invasive Assessment of Early Health Determinants in Children and Adolescents
NCT07861516Cardiometabolic Health Indicators, Child Health
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
2,000
Rome
2026-10-01
Not yet open
Trcheal High-flow for Weaning From Mechanical Ventilation
NCT07714564Tracheostomy, Mechanical Ventilation, Hypoxemic Respiratory Failure
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
500
Rome
2026-10-01
Not yet open
TOLerogenic Potential of Hematopoietic Stem and Progenitor Cells and Inflammatory Bowel Disease
NCT07740499Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
IRCCS San Raffaele
Observational
80
Milan, Rome
2026-10
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Rome
2026-10
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
90
Ancona, Florence, Genova, Messina, Milan, Roma, Rome, Verona
2026-09-15
Recruiting
CSL Behring
Phase 3
63
Rome, Brescia, Varese, Candiolo, Catania, Florence, Milan
2026-09-15
Recruiting
Takeda
Phase 3
324
Bologna, Cona, Meldola, Rome, Milan, Ancona, Catania, Florence
2026-09-10
Not yet open
Liaquat University of Medical & Health Sciences
Not applicable
255
Piacenza, Guidonia Montecelio, Rome, Urbino
2026-09-07
Not yet open
Liaquat University of Medical & Health Sciences
Not applicable
140
Rome, Mercato San Severino
2026-09-07
Not yet open
Parkinson's Research In Metagenomic Early Stage Biomarkers
NCT07097103Parkinson's Disease (PD)
IRCCS San Raffaele Roma
Not applicable
80
Cassino, Rome
2026-09-01
Not yet open
Targeting MYC in High-Risk Medulloblastoma
NCT07694622Medulloblastoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
35
Rome
2026-09-01
Not yet open
TL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP)
NCT07642297Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic Sclerosis, Skin Fibrosis
Fondazione Policlinico Universitario Campus Bio-Medico
Observational
20
Rome
2026-09-01
Recruiting
IRCCS San Raffaele Roma
Not applicable
32
Rome
2026-09-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,125
Rome
2026-09
Recruiting
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07845487Ulcerative Colitis (UC), Severe Ulcerative Colitis, Moderate Ulcerative Colitis
DrugPALI-2108
Palisade Bio
Phase 2
204
Bari, Bologna, Matera, Negrar, Rome, Rozzano, San Giovanni Rotondo, Turin
2026-08-28
Not yet open
AstraZeneca
Phase 3
750
Bologna, Milan, Rome, Rozzano, Torino
2026-08-25
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
25
Roma, Rome
2026-08-20
Not yet open
Supply Induced Demand in Intensive Care Unit: a Retrospective Trial
NCT07768410Intensive Care (ICU), Intensive Care Unit (ICU) Admission, Intensive Care Unit Survivors, SID
Saint Camillus International University of Health Sciences
Observational
1,500
Rome
2026-08-20
Recruiting
Pivotal Study of N-acetyl-L-leucine for CACNA1A
NCT07221292CACNA1A, Spinocerebellar Ataxia Type 6, Episodic Ataxia Type 2, Familial Hemiplegic Migraine-1
DrugN-Acetyl-L-Leucine
IntraBio Inc
Phase 3
60
Milan, Rome
2026-08-17
Active, closed
Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt
NCT05776758Muscle-Invasive Bladder Carcinoma, Chemotherapy Effect, Surgery
Regina Elena Cancer Institute
Phase 3
236
Rome
2026-08-13
Not yet open
GlaxoSmithKline
Phase 3
1,860
Bari, Foggia, Rome
2026-08-11
Not yet open
Shh Signaling in Brain AVMs: Novel Player & Therapeutic Target
NCT07676721Brain Arteriovenous Malformations (AVMs)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
45
Rome
2026-08-01
Not yet open
Entrada Therapeutics, Inc.
Phase 2
80
Milan, Roma, Rome
2026-08
Recruiting
Clinical, Oncologic, and Metabolic Effects of Pancreatic Mass Loss After Pancreatectomy in Non-Diabetic Patients
NCT07608055Pancreatectomy, Diabetes Mellitus Type 2, Pancreatic Neoplasms
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
579
Rome
2026-07-20
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
150
Rome
2026-07-15
Recruiting
Fondazione Telethon
Phase 2
9
Rome, Milan
2026-07-06
Not yet open
Air-in-Line Alarms During Antineoplastic Drug Infusion
NCT07718711Infusion Safety, Medication Safety, Antineoplastic Drug Administration, Air-in-Line Alarm
Associazione Italiana Infermieri di Area Oncologica
Observational
40
Parma, Rome, Lodi, Milan
2026-07-01
Recruiting
Evolution of Chronic Inflammatory Skin Diseases
NCT07708896Inflammatory Skin Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
5,000
Rome
2026-07-01
Recruiting
Influence of Early Wound Healing on the Outcomes of Regenerative Periodontal Surgery
NCT07683962Intrabony Periodontal Defect, Wound Healing
University of Roma La Sapienza
Observational
100
Rome
2026-07
Recruiting
AstraZeneca
Phase 3
750
Bologna, Milan, Rome, Rozzano, Torino
2026-06-26
Recruiting
AbbVie
Observational
200
Rome
2026-06-26
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
600
Rome
2026-06-26
Not yet open
Liaquat University of Medical & Health Sciences
Not applicable
400
Montevarchi, Rome, Salerno, Urbino
2026-06-22
Recruiting
Merck Sharp & Dohme LLC
Phase 3
310
Meldola, Rome, Milan
2026-06-18
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
12,500
Rome
2026-06-13
Recruiting
Regeneron Pharmaceuticals
Phase 3
35
Rome, Florence, Torino
2026-06-11
Recruiting
University of Roma La Sapienza
Not applicable
80
Rome
2026-06-08
Recruiting
AstraZeneca
Phase 2
80
Meldola, Milan, Padua, Ravenna, Rome, Torino
2026-06-04
Not yet open
Matthias Stuber
Observational
300
Rome
2026-06
By invitation
Novo Nordisk A/S
Observational
214
Pescara, San Giovanni in Fiore (CS), Marano Di Napoli (NA), Rome, Milan, Cuneo, Catania, Bolzano
2026-05-28
Recruiting
Hoffmann-La Roche
Phase 2
30
Rome, Brescia, Rozzano
2026-05-25
Recruiting
Hoffmann-La Roche
Phase 2/3
650
Naples, Meldola, Parma, Aviano, Rome, Bergamo, Brescia, Milan
2026-05-21
Recruiting
Incyte Corporation
Phase 2
60
Bologna, Genova, Monza, Padua, Pavia, Rome
2026-05-20
Recruiting
AbbVie
Phase 1
18
Rome
2026-05-20
Recruiting
Longitudinal Profiling of Plasma-Derived Glial Extracellular Vesicles in Alzheimer's Disease
NCT07803055Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, Alzheimer's Disease Dementia, Alzheimer's Disease (AD)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
48
Rome
2026-05-18
Recruiting
Merck Sharp & Dohme LLC
Phase 2/3
340
Bergamo, Rome
2026-05-18
Recruiting
Clinical Study of DA-020 for the Treatment of Chemotherapy Induced Alopecia
NCT07397325Chemotherapy Induced Alopecia, Chemotherapy Side Effects
DrugDA-020
Applied Biology, Inc.
Phase 1/2
60
Rome
2026-05-16
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
300
Rome
2026-05-13
Recruiting
Hoffmann-La Roche
Phase 3
8
Rome, Pavia
2026-05-06
Recruiting
Mirati Therapeutics Inc.
Phase 2
170
Orbassano, Rome, Florence, Bologna, Meldola, Milan, Pesaro, Roma
2026-05-06
Recruiting
TENS for Restoring Somatotopic Sensory Feedback in Lower Limb Amputees and Improving Phantom Limb Perception
NCT07448350Lower Limb Amputation Above Knee, Lower Limb Amputation Below Knee
Campus Bio-Medico University
Not applicable
15
Rome
2026-05-05
Not yet open
MISTIC Study: Atherosclerosis, Neurocognition & Cardiovascular Signaling
NCT07520643Subclinical Atherosclerotic Cardiovascular Disease, Neurocognitive Decline
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Rome
2026-05-01
Not yet open
Breath Test-Based Assessment of SIBO in Chronic Pancreatitis and Partial Pancreatectomy
NCT07479238SIBO, Pancreatic Insufficiency, Chronic Pancreatitis, Pancreatic Surgey
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Rome
2026-04-30
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
NCT07285655Pulmonary Hypertension Due to Lung Disease (Disorder)
Liquidia Technologies, Inc.
Phase 3
344
Genoa, Rome
2026-04-23
Not yet open
Multi-omics Dissection of Gut Microbiome Engraftment During FMT
NCT06992453Recurrent C. Difficile (rCDI), Ulcerative Colitis (UC), Metabolic Syndrome (MetS)
Catholic University of the Sacred Heart
Not applicable
90
Rome
2026-04-23
Active, closed
Integrated Clinical-Occupational Management for Workers With Chronic Noncommunicable Diseases
NCT07694609Inflammatory Bowel Diseases (IBD), Crohn Disease, Ulcerative Colitis (UC)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
200
Rome, Naples
2026-04-23
Recruiting
Novo Nordisk A/S
Phase 3
400
Udine, Rome, Milan, San Donato Milanese, Verona
2026-04-20
By invitation
BioMarin Pharmaceutical
Phase 2
18
Milan, Rome
2026-04-20
Recruiting
ASO Treatment for Syndromic Craniosynostoses
NCT07535372Craniosynostoses, Crouzon Syndrome, Saethre Chotzen Syndrome, Muenke Syndrome
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
12
Rome
2026-04-20
Recruiting
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 3
420
Bologna, Milan, Naples, Prato, Rome
2026-04-17
Not yet open
Pharmacokinetic Study of DA-020
NCT07402330Chemotherapy Induced Alopecia, Chemotherapy Side Effects
DrugDA-020
Applied Biology, Inc.
Early Phase 1
60
Rome
2026-04-16
Recruiting
Novo Nordisk A/S
Phase 3
630
Bologna, Rome, Milan, Palermo
2026-04-13
Recruiting
Novo Nordisk A/S
Phase 3
400
Naples, Modena, Udine, Rome, Milan, San Donato Milanese, Verona
2026-04-13
Recruiting
Gut Microbiome in Patients With Post-infectious Irritable Bowel Syndrome
NCT07517029IBS - Irritable Bowel Syndrome, Post Infection Syndrome
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
315
Rome
2026-04-08
Recruiting
Hoffmann-La Roche
Phase 2
80
Naples, Meldola, Rome, Bergamo, Milan
2026-04-07
Not yet open
Charite University, Berlin, Germany
Phase 3
750
Rome
2026-04-01
Recruiting
Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer
NCT07510698Breast Cancer, Mastectomy, Prepectoral Breast Reconstruction, ERAS Programmes
University of Rome Tor Vergata
Not applicable
100
Rome
2026-04-01
Not yet open
Microplastics in Pancreas: Oncologic and Metabolic Impact
NCT07486128Pancreatic Diseases, Pancreatic Neoplasms
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
10
Rome
2026-04-01
Recruiting
EMD Serono Research & Development Institute, Inc.
Phase 3
202
Rome, Verona
2026-04-01
Recruiting
University of Roma La Sapienza
Not applicable
150
Rome
2026-04-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
300
Rome
2026-04
Recruiting
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
NCT07415044Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe
DrugZotemtegrast
Eli Lilly and Company
Phase 2
1,431
Milan, Rho, Rome, Rozzano
2026-03-26
Recruiting
Hoffmann-La Roche
Phase 3
1,600
Bergamo, Catanzaro, Bologna, Rome, Milan, Palermo, Perugia
2026-03-23
Recruiting
Liaquat University of Medical & Health Sciences
Not applicable
132
Forlì, Ravenna, Rome, Brescia, Pavia, Turin, Catania, Florence
2026-03-23
Recruiting
Santen SAS
Observational
112
Rome, Turin
2026-03-19
Recruiting
SymBio Pharmaceuticals
Phase 3
180
Genova, Pavia, Perugia, Rome, San Raffaele
2026-03-17
Recruiting
Hoffmann-La Roche
Phase 3
2,000
Bergamo, Bari, Catanzaro, Bologna, Rome, San Donato Milanese (MI), Palermo, Pisa
2026-03-16
Recruiting
Bristol-Myers Squibb
Phase 3
850
Naples, Ravenna, Aviano, Orbassano, Rome, Milan, Parma
2026-03-16
Recruiting
Sanofi
Phase 2/3
526
Torette, Milan, Rome, Bologna, Brescia, Novara
2026-03-13
Recruiting
Hoffmann-La Roche
Phase 2
100
Rome, Milan
2026-03-11
Recruiting
Identification of Biomarkers in Cervical Mucus
NCT06771401Cervical Mucus Dysfunction, Infertility, Female
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
24
Rome
2026-03-10
Recruiting
Eli Lilly and Company
Phase 4
150
Alessandria, Florence, Messina, Monza, Perugia, Rome, Terni
2026-03-09
Recruiting
Alexion Pharmaceuticals, Inc.
Phase 4
75
Milan, Naples, Rome
2026-03-04
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
20
Rome
2026-02-28
Recruiting
Zealand Pharma
Phase 3
90
Rome, Milan, Padova
2026-02-11
Recruiting
GLS in Difficult CPB Weaning
NCT07390903Cardiopulmonary Bypass, Coronary Artery Bypass, Heart Valve Diseases, Echocardiography
Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Observational
213
Rome
2026-02-05
Recruiting
Cognitive-motor Technology Rehabilitation in Frail Individuals
NCT07292428Frail, Sensorimotor Deficits
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
80
Rome, Vibo Valentia
2026-02-02
Recruiting
Exciva GmbH
Phase 2/3
300
Rome, Tricase, Brescia, Milan, Palermo
2026-02-02
By invitation
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
30
Rome
2026-02-01
Recruiting
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
500
Rome
2026-02-01
Recruiting
A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-study
NCT06594393Epidermolysis Bullosa (EB), Dystrophic Epidermolysis Bullosa, Junctional Epidermolysis Bullosa
Xinnate AB
Phase 2
32
Rome
2026-01-30
Active, closed
A Trial of TAK-861 for the Treatment of Narcolepsy With Cataplexy
NCT07363720Narcolepsy Type 1 (NT1), Narcolepsy With Cataplexy
DrugTAK-861
Takeda
Phase 3
98
Bologna, Rome
2026-01-29
Recruiting
Spleen Stiffness Measurement for the Detection of Advanced Fibrosis
NCT07440511MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
500
Rome
2026-01-28
Recruiting
Kymera Therapeutics, Inc.
Phase 2
264
Rome
2026-01-28
Recruiting
IDEAYA Biosciences
Phase 3
520
Naples, Milan, Perugia, Florence, Pisa, Rome
2026-01-25
Recruiting
Eikon Therapeutics
Phase 1/2
160
Rome
2026-01-20
Recruiting
Evaluation of the Effectiveness of an Educational Intervention in Splenectomized Patients
NCT07354893Splenectomized Patients, Splenectomy, Splenectomy; Status, Asplenia
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Rome, Roma
2026-01-13
Recruiting
Hoffmann-La Roche
Phase 2
120
Rome, Ancona
2026-01-08
Recruiting
Incyte Corporation
Phase 1
280
Bologna, Milan, Rome, Verona
2026-01-08
Recruiting
University Hospital, Basel, Switzerland
Not applicable
1,060
Padova, Rome
2026-01-01
Recruiting
Development of an Italian Questionnaire for Splenectomized Patients Using a Delphi Consensus Method
NCT07428005Splenectomy; Status, Asplenia, Splenectomized Patients
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
20
Rome
2026-01-01
Recruiting
Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs)
NCT05962541Non-muscle-invasive Bladder Cancer, Non-Muscle Invasive Bladder Urothelial Carcinoma, High Risk Non-Muscle Invasive Bladder Urothelial Carcinoma
DrugHexvix
University of Roma La Sapienza
Phase 4
327
Rome
2025-12-22
Recruiting
Novo Nordisk A/S
Phase 3
332
Rome, Bergamo, Messina, Rivoli, Genova, Novara, Orbassano, San Donato Milanese
2025-12-18
Recruiting
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
NCT07218380Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis
DrugsVepugratinib·Pembrolizumab
Eli Lilly and Company
Phase 3
450
Bari, Milan, Naples, Padova, Pisa, Roma, Rome
2025-12-12
Recruiting
DCEUS to Assess Treatment Response to PRRT in GEP-NET
NCT07319416NET, Radionucleide Therapy, Contrast Enhanced Ultrasound
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
30
Rome
2025-12-11
Recruiting
AbbVie
Phase 2/3
490
Milan, Monza, Fano, Aviano, Rome, Candiolo, Catania, Verona
2025-12-10
Recruiting
Hoffmann-La Roche
Phase 2
160
Reggio Emilia, Rome, Rozzano
2025-12-05
Recruiting
AstraZeneca
Phase 3
1,100
Castellana Grotte, Milan, Pisa, Rome, Rozzano
2025-12-04
Recruiting
Takeda
Phase 3
110
Catania, Padova, Rome
2025-12-04
Recruiting
Bristol-Myers Squibb
Phase 3
366
Rome, Roma
2025-12-03
Recruiting
Sanofi
Phase 2
37
Rome, Turin, Monza
2025-12-02
Recruiting
Bristol-Myers Squibb
Phase 3
650
Naples, Rome, Milan, Pisa, Brescia, Isernia, Roma
2025-12-02
Recruiting
Changes in Taste and Eating Habits Associated With GLP-1 Agonists in Weight Loss Patients
NCT07229170Obesity & Overweight, Taste Alterations, Weight Loss, Eating Behavior Changes
San Raffaele Telematic University
Observational
150
Roma, Rome
2025-12-01
Recruiting
Hoffmann-La Roche
Phase 3
250
Naples, Cona (Ferrara), Rome, Milan, Novara, Palermo
2025-11-27
Active, closed
Itaca App vs. Usual Care for Medication Adherence in Older Adults on Polypharmacy
NCT07631676Medication Adherence, Poly Pharmacy, Chronic Disease, Older Adults (65 Years and Older)
University of Roma La Sapienza
Not applicable
120
Rome
2025-11-26
Recruiting
Merck Sharp & Dohme LLC
Phase 3
904
Naples, Rome, Milan, Rozzano, Orbassano, Florence, Castelfranco Veneto, Peschiera del Garda
2025-11-26
Recruiting
AbbVie
Phase 2
180
Rome, Orbassano, Roma
2025-11-25
Recruiting
Hoffmann-La Roche
Phase 3
900
Naples, Salerno, Bologna, Cassino, Rome, Genoa, Brescia, Milan
2025-11-24
Recruiting
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
NCT07087054Carcinoid Syndrome, Carcinoid, Carcinoid Tumor, Carcinoid Tumor of Ileum
Crinetics Pharmaceuticals Inc.
Phase 3
141
Bologna, Milan, Rome, Turin
2025-11-19
Recruiting
Incyte Corporation
Phase 3
250
Bologna, Brescia, Catania, Milan, Naples, Padua, Roma, Rome
2025-11-13
Active, closed
Hoffmann-La Roche
Phase 2
193
Foggia, Naples, Rome, Milan, Pozzilli
2025-11-13
Active, closed
Hoffmann-La Roche
Phase 3
1,060
Naples, Modena, Rome, Perugia
2025-11-12
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
65
Rome
2025-11-12
Active, closed
Novo Nordisk A/S
Phase 3
300
Rome, Palermo, Bologna, Milan
2025-11-05
Recruiting
AbbVie
Phase 3
561
Cona, Florence, Rome, Ancona, Reggio Emilia
2025-11-05
Recruiting
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
NCT07085767Breast Cancer, Locally Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer
DrugsPalazestrant·Ribociclib·Letrozole
Olema Pharmaceuticals, Inc.
Phase 3
1,000
Naples, Bologna, Aviano, Rome, Genoa, Bergamo, Milan, Monza
2025-11-03
Recruiting
Takeda
Phase 2
200
Rozzano, Rome, Brescia, Florence
2025-11-03
Recruiting
Role of Nutritional Status in Functional Recovery of Older Adults Undergoing Virtual Reality-augmented Shoulder Rehabilitation (VIR)
NCT07282561Shoulder Arthroplasty, Rehabilitation, Virtual Reality, Malnutrition Elderly
Claudio Pedone
Not applicable
60
Rome
2025-11-01
Not yet open
Leonardo Calò, MD
Not applicable
194
Rome
2025-10-30
Recruiting
Hoffmann-La Roche
Phase 3
600
Statte, Naples, Modena, Pesaro, Aviano, Rome, Milan, Monza MI
2025-10-24
Active, closed
Bristol-Myers Squibb
Phase 2/3
470
Meldola, Rome, Milan, Rozzano, Pisa, Padova, Naples, Verona
2025-10-23
Active, closed
CRUCIAL-R Study : Cruciferous Vegetables Dietary Regimen in NMIBC
NCT07391137Recurrence Free Survival, Bladder Cancer Recurrence
S. Andrea Hospital
Not applicable
250
Rome
2025-10-17
Recruiting
Sanofi
Phase 2
54
Milan, Padua, Rome, Turin
2025-10-14
Active, closed
Ultragenyx Pharmaceutical Inc
Phase 2
60
Florence, Milan, Rome
2025-10-13
Not yet open
Clinical Study of DA-007 for the Treatment of Chemotherapy Induced Alopecia
NCT06762548Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Applied Biology, Inc.
Phase 3
140
Rome
2025-10-10
Recruiting
Merck Sharp & Dohme LLC
Phase 3
675
Bolzano, Modena, Meldola, Udine, Rome, Bergamo, Rozzano, Statte
2025-10-08
Recruiting
CatalYm GmbH
Phase 2
131
Forlì, Aviano, Rome, Ravenna
2025-10-07
Not yet open
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
NCT06802198Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
500
Rome
2025-10-01
Recruiting
AllRock Bio, Inc.
Phase 2
40
Foggia, Pavia, Rome
2025-10-01
Recruiting
Sanofi
Phase 3
980
Rome, Rozzano, Turin
2025-10-01
Recruiting
Bristol-Myers Squibb
Phase 2/3
470
Bari, Genoa, Rome, Pisa, Castelfranco Veneto, Milan, Naples, Parma
2025-09-30
Recruiting
Alfasigma S.p.A.
Phase 3
80
Alessandria, Ancona, Milan, Naples, Rome, Trieste
2025-09-29
Recruiting
Genentech, Inc.
Phase 2
224
Rome, Brescia, Milan, Rho, Rozzano, San Donato Milanese (MI), Turin, Negrar
2025-09-29
Recruiting
Pfizer
Phase 3
680
Aviano, Rome, Roma, Florence, Verona, Bergamo, Caserta, Genova
2025-09-29
Recruiting
Pfizer
Phase 3
1,000
Meldola, Ravenna, Rozzano, Orbassano, Rome, Milan, Novara, Padova
2025-09-28
Active, closed
Hoffmann-La Roche
Phase 3
1,101
Rome, Genoa, Brescia, Milan
2025-09-17
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
115
Rome
2025-09-15
Recruiting
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy
NCT07047144Spinal Muscular Atrophy, SMA, Spinal Muscular Atrophy Type 2, Spinal Muscular Atrophy Type 3
DrugsApitegromab·Nusinersen·Risdiplam
Scholar Rock, Inc.
Phase 2
52
Milan, Rome
2025-09-15
By invitation
Lupin Ltd.
Phase 3
176
Rome
2025-09-12
Recruiting
AbbVie
Observational
700
L’Aquila, Milan, Naples, Rome, Genova
2025-09-09
Recruiting
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
NCT07011719Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma
DrugsCasdatifan·Cabozantinib
Arcus Biosciences, Inc.
Phase 3
720
Florence, Genova, Milan, Naples, Padua, Perugia, Rome, Rozzano
2025-09-08
Recruiting
Effects of Pasireotide Lar Therapy on Bone Metabolism
NCT07179926Acromegaly Due to Pituitary Adenoma, Acromegaly
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
120
Rome
2025-09-08
Recruiting
AbbVie
Observational
2,795
Cona, Rome, Bari
2025-09-02
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
300
Rome
2025-09-01
Recruiting
Biophotonic Nanoparticle-enabled Laser Blood Test for Early Detection of Pancreatic Cancer
NCT07659639Diabetes, IPMN, Pancreatic, PDAC - Pancreatic Ductal Adenocarcinoma
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
400
Rome
2025-09-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Rome, Catania, Catanzaro, Reggio Calabria
2025-09-01
Recruiting
Proactive Hemodynamic Management During Cytoreductive Surgery and HIPEC
NCT07070973Ovarian Cancer, Hemodynamic Instability, Fluid Overload
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
52
Rome
2025-09-01
Recruiting
Virtual Reality for Shoulder Rehabilitation
NCT06797492Shoulder Musculoskeletal Disorders
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
50
Roma, Rome
2025-09-01
Active, closed
Starring Optical Coherence Tomography During Percutaneous Coronary Intervention Guidance
NCT07182799Acute Coronary Syndromes (ACS), Chronic Coronary Syndrome, MINOCA, INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
3,200
Rome
2025-09-01
Recruiting
Entrada Therapeutics, Inc.
Phase 1/2
24
Milan, Rome
2025-08-30
Active, closed
An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)
NCT06961344Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Tisento Therapeutics
Phase 2
44
Milan, Rome
2025-08-18
Recruiting
Neurocrine Biosciences
Phase 3
550
Milan, Roma, Rome, Torino
2025-08-18
Recruiting
Novo Nordisk A/S
Phase 4
586
Bari, Catanzaro, Naples, Rome, Milan, Messina, Palermo, Fermo
2025-08-15
Recruiting
Treatment Expedition With MRI Processing and Optimization for Muscle Invasive Bladder Cancer
NCT07067749Bladder (Urothelial, Transitional Cell) Cancer, Bladder Cancer Requiring Cystectomy, Bladder Carcinoma, Bladder Neoplasm
University of Rome Tor Vergata
Phase 3
92
Rome
2025-08-15
Recruiting
Takeda
Phase 3
150
Naples, Rome, Catania, Bologna, Milan, Monza, Novara, Torino
2025-08-14
Recruiting
A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
NCT07019922Epileptic Encephalopathy, SCN2A Encephalopathy
Praxis Precision Medicines
Phase 3
40
Rome
2025-08-13
Recruiting
Sanofi
Phase 3
192
Florence, Milan, Naples, Rome, Orbassano, Palermo, Verona
2025-08-12
Recruiting
Regina Elena Cancer Institute
Observational
82
Rome
2025-08-07
Recruiting
Sanofi
Phase 3
723
Florence, Genoa, Milan, Rome, Turin, Bologna, Messina, Novara
2025-08-06
Recruiting
Miltenyi Biomedicine GmbH
Phase 2
31
Rome
2025-08-04
Recruiting
AbbVie
Phase 2/3
854
Rome, Orbassano, Perugia, Roma
2025-08-03
Recruiting
HOPE Against Cancer Recurrence in HCC
NCT06717919Liver Transplantation, HCC, Oncological Outcomes
Philipp Dutkowski
Phase 4
220
Milan, Padova, Rome, Udine
2025-08-01
Active, closed
Serratus Posterior Superior Intercostal Plane (SPSIP) Block Versus Intercostal Nerve (ICN) Block in Patients Undergoing Uniportal-VATS.
NCT07250373Uniportal-VATS, Lung Resection Procedures, Locoregional Anesthesia, Post-operative Pain Management
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
28
Rome
2025-08-01
Recruiting
CatalYm GmbH
Phase 2
107
Meldola, Milan, Aviano, Ravenna, Rome
2025-08-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
20
Rome
2025-07-31
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
1,922
Rome
2025-07-30
Recruiting
AbbVie
Phase 3
120
San Giovanni Rotondo, Naples, Rome, Trieste
2025-07-28
Recruiting
Regina Elena Cancer Institute
Observational
5
Rome
2025-07-24
Recruiting
Pfizer
Phase 3
714
Naples, Misterbianco, Meldola, Pesaro (PU), Orbassano, Rome, Roma, Catania
2025-07-23
Recruiting
Pushing Using Real-time Sonographic Ultrasound Education
NCT07000240Transperineal Ultrasound, Midwife-led Pushing Training Program, Duration of the Second Stage, Coactivation Rates of Pelvic Floor Muscles
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
136
Rome
2025-07-19
Recruiting
Bristol-Myers Squibb
Phase 3
426
Naples, Rome, Milan, Pisa, Brescia, Isernia, Roma
2025-07-16
Recruiting
University Hospital, Basel, Switzerland
Phase 2
150
Milan, Rome
2025-07-15
Recruiting
Hoffmann-La Roche
Observational
700
Lecce, Naples, Modena, Ravenna, Rome, Genoa, Bergamo, Milan
2025-07-15
Active, closed
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 2
89
Rome, Milan, Pisa
2025-07-14
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
269
Rome
2025-07-10
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
64
Rome
2025-07-07
Recruiting
Hoffmann-La Roche
Phase 3
80,000
Naples, Rome, Genoa, Brescia, Milan, Palermo, Perugia
2025-07-02
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
300
Rome
2025-07-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
107
Rome
2025-07
Active, closed
Immunovant Sciences GmbH
Phase 2
180
Catania, Milan, Palermo, Perugia, Rome
2025-06-30
Recruiting
Entrada Therapeutics, Inc.
Phase 1/2
24
Milan, Rome
2025-06-30
Recruiting
Pharmacokinetic Study of Topical Phenylephrine
NCT07033845Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Applied Biology, Inc.
Early Phase 1
24
Rome
2025-06-30
Recruiting
Hoffmann-La Roche
Phase 3
75
Rome, Milan, Florence
2025-06-27
Recruiting
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
NCT06995677Low-grade NMIBC, FGFR Gene Amplification, FGFR Gene Alterations, FGFR3 Gene Alteration
DrugTYRA-300
Tyra Biosciences, Inc
Phase 2
90
Rome, Milan, Pisa, Pozzuoli
2025-06-27
By invitation
BioMarin Pharmaceutical
Phase 3
140
Genoa, Rome
2025-06-20
Active, closed
Incyte Corporation
Phase 3
159
Catania, Milan, Naples, Padova, Rome
2025-06-17
Active, closed
AbbVie
Phase 3
573
Monserrato, Rozzano, Milan, Naples, Rome, Bologna, Padova, Palermo
2025-06-17
Recruiting
Proteomic and Histological Analysis of Ligamentum Flavum in Lumbar Stenosis
NCT07026552Spinal Stenosis of Lumbar Region, Spine Degeneration
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Rome
2025-06-15
Recruiting
Calico Life Sciences LLC
Phase 2
240
Bari, Modena, Rome
2025-06-09
Active, closed
Biogen
Phase 3
255
Rome, Conegliano, Milan
2025-06-09
Recruiting
AbbVie
Observational
270
Troina, Pozzilli, Milan, Naples, Turin, Rome, Venice, Ancona
2025-06-04
Recruiting
KU Leuven
Observational
400
Milan, Rome
2025-06-03
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
80
Rome
2025-06-01
Recruiting
Delta Variation to Guide Hemodynamic Optimization
NCT06932484Hemodynamic MAP Stability
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
104
Rome
2025-06-01
Not yet open
Cerebral Regional Oxygen Saturation During TAVI - The CROS-TAVI Prospective Registry
NCT07016789Aortic Stenosis Disease, TAVI(Transcatheter Aortic Valve Implantation), Cerebral Oxygen Saturation, Hemodynamic Changes
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
40
Rome
2025-06
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
3,600
Roma, Rome
2025-05-29
By invitation
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
15
Rome
2025-05-28
Active, closed
Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)
NCT06931405Chronic Inducible Urticaria, Chronic Spontaneous Urticaria
Blueprint Medicines Corporation
Phase 2
105
Padova, Rome, Verona
2025-05-28
Recruiting
Immunovant Sciences GmbH
Phase 3
231
Bergamo, Milan, Naples, Rome
2025-05-27
Recruiting
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
200
Candiolo, Florence, Milan, Padova, Palermo, Rome
2025-05-27
Recruiting
Chiesi Farmaceutici S.p.A.
Observational
10
Rome
2025-05-23
Recruiting
Pembrolizumab and Radiotherapy for Oligometastatic Head and Neck Cancer
NCT05815927Oligometastatic Squamous Cell Carcinoma of the Head and Neck
DrugPembrolizumab
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3
200
Bologna, Cuneo, Florence, Milan, Naples, Ravenna, Rome
2025-05-23
Active, closed
Sanofi
Phase 3
1,092
Rome, Bari, Foggia, Lecce, Milan, Parma
2025-05-22
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
20
Rome
2025-05-20
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
160
Acerenza, Bari, Genova, Messina, Milan, Montescano, Pavia, Rome
2025-05-20
Recruiting
Cullinan Therapeutics Inc.
Phase 1
37
Rome
2025-05-19
Recruiting
SecuraBio
Phase 3
124
Alessandria, Bergamo, Bologna, Naples, Rome
2025-05-19
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
300
Rome
2025-05-15
By invitation
Prometheus: Prophylactic Mesh After OLtx for Hernia Reduction Study.
NCT07744230Incisional Hernia/Prevention and Control
University of Rome Tor Vergata
Observational
100
Rome
2025-05-15
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,440
Milan, Rozzano, Rome, Siena, Arezzo, Bergamo, Foggia, Terni
2025-05-13
Recruiting
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
NCT06563895Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies
DrugAcoramidis
Eidos Therapeutics, a BridgeBio company
Phase 3
587
Bologna, Florence, Pavia, Pisa, Roma, Rome
2025-05-12
Recruiting
Hoffmann-La Roche
Phase 3
425
Matera, Bologna, Rome, Brescia, Milan, San Donato Milanese (MI), Negrar
2025-05-12
Recruiting
Takeda
Phase 2
88
Rome, Verona, Bologna
2025-05-06
Recruiting
Takeda
Phase 3
225
Ancona, Turin, Florence, Milan, Pavia, Reggio Calabria, Rome, Rozzano
2025-05-06
Active, closed
Cartesian Therapeutics
Phase 3
128
Rome
2025-05-06
Recruiting
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
NCT06881784NSCLC (Non-small Cell Lung Cancer), Non-Small Cell Lung Cancer, NSCLC, NSCLC (Non-small Cell Lung Carcinoma)
DrugsCetuximab·Docetaxel
Revolution Medicines, Inc.
Phase 3
590
Milan, Rossano, Monza, Naples, Pisa, Roma, Rome
2025-05-06
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
24
Rome
2025-05-01
Recruiting
I.R.C.C.S. Fondazione Santa Lucia
Not applicable
30
Rome
2025-05-01
Not yet open
Incidence of Body Dysmorphic Disorder (BDD) in a Population of Patients Undergoing Orthognathic Surgery
NCT06879275Orthognathic Surgical Procedures, Psychiatric Disorders, Prognathism
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
90
Rome
2025-05-01
Active, closed
Ascending Doses of Crofelemer Powder for Oral Solution in Pediatric Microvillus Inclusion Disease (MVID)
NCT06721871Microvillus Inclusion Disease, Congenital Disorders, Rare Diseases
DrugCrofelemer
Napo Pharmaceuticals, Inc.
Phase 2/3
6
Rome
2025-05-01
By invitation
ESCAPE10: Epidemiology, Risk Factors, and Outcomes of Severe Community-acquired Pneumonia in Elderly Patients Acquired Pneumonia in Elderly Patients
NCT07070284Severe Community-Acquired Pneumonia (sCAP), Elderly Infection, Community-Acquired Infections, Health Care Quality, Access, and Evaluation
Joan Sabater-Riera
Observational
500
Modena, Rome, Gavardo, Palermo, Pisa
2025-05-01
Recruiting
Istituto Superiore di Sanità
Not applicable
128
Naples, Rome
2025-05
Active, closed
Hoffmann-La Roche
Observational
44
Rome, Milan, Florence
2025-04-29
Recruiting
Vortioxetine in Depression and Concomitant Migraine
NCT07579481Depression, Migraine
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
31
Rome
2025-04-28
Recruiting
Mirati Therapeutics Inc.
Phase 3
630
Bari, Meldola, Naples, Orbassano, Rome, Florence, Genova, Padova
2025-04-24
Recruiting
Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers
NCT06906341Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms, Endometrial Cancer
DrugsNab-paclitaxel /m^2·Relacorilant·Bevacizumab
Corcept Therapeutics
Phase 2
270
Catania, Milan, Pavia, Rome, Torino, Treviso
2025-04-11
Recruiting
Hemodynamic Monitoring Carotid Surgery
NCT06926010Carotid Artery Diseases, Haemodynamic Monitoring
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
120
Rome
2025-04-10
Recruiting
OHANA: Optimizing Cross-Cultural Care
NCT06944678Cultural Competence
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
20
Rome
2025-04-10
Recruiting
University of Rome Tor Vergata
Observational
30
Rome
2025-04-10
Recruiting
Hoffmann-La Roche
Phase 3
450
Tricase (LE), Caserta, Naples, Bologna, Meldola, Modena, Rome, Bergamo
2025-04-09
Recruiting
Bristol-Myers Squibb
Phase 3
194
Naples, Milan, Rome
2025-04-08
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
5,000
Rome
2025-04-07
Recruiting
Vifor Pharma, Inc.
Phase 2
36
Milan, Rome
2025-04-06
Active, closed
Hoffmann-La Roche
Phase 2
30
Rome, Milan
2025-04-04
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
2,400
Rome
2025-04-03
Not yet open
Patient's Derived Organoids for Drug Screening in Glioblastoma
NCT06781372Glioblastoma, Glioblastoma Multiforme (GBM), Glioblastoma Multiforme, Adult
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
100
Rome
2025-04-01
By invitation
Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP
NCT06859099Polyneuropathy, Inflammatory Demyelinating, Chronic
DrugRiliprubart
Sanofi
Phase 3
300
Genoa, Milan, Rozzano, Rome, Pavia, Pisa
2025-04-01
Not yet open
In Vitro Study of [18F]F-FAPI-74 Feasibility in Vulvar Cancer
NCT06911801Vulvar Squamous Cell Carcinoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
90
Rome
2025-04
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
149
Rome
2025-03-30
Active, closed
Sanofi
Phase 2
204
Genoa, Milan, Rozzano, Naples, Padua, Rome, Turin, Alessandria
2025-03-28
Recruiting
AbbVie
Observational
700
Milan, Naples, Turin, Rome, Bari, Palermo
2025-03-28
Recruiting
AstraZeneca
Phase 3
600
Catania, Florence, Milan, Monza, Naples, Reggio Emilia, Roma, Rome
2025-03-27
Recruiting
Daiichi Sankyo
Phase 3
510
Milan, Naples, Padova, Rome, Rozzano
2025-03-27
Recruiting
Fondazione Ricerca Traslazionale
Phase 2
30
Rome
2025-03-27
Active, closed
Meningococcal Vaccination in Patients on Complement Inhibitors
NCT06906692Myasthenia Gravis Generalised, Vaccination, Complement System, Neuromyelitis Optica Spectrum Disease (NMOSD)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
35
Rome
2025-03-25
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
50
Rome
2025-03-24
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
43
Rome
2025-03-20
Recruiting
Catholic University of the Sacred Heart
Not applicable
100
Rome
2025-03-17
Recruiting
Hoffmann-La Roche
Phase 3
600
Bari, Catanzaro, Naples, Rome, Milan, Monza MI, Pavia, Rho
2025-03-17
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,000
Rome, Bologna, Genova, Milan, Novara, Padova, Roma
2025-03-16
Active, closed
Hoffmann-La Roche
Phase 4
274
Foggia, Rome, Milan, Napoli, Torrette - Ancona
2025-03-14
Recruiting
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
120
Rome, Roma, Naples
2025-03-13
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
400
Rome
2025-03-13
Active, closed
Celgene
Phase 3
960
Milan, Orbassano, Rome, Padova, Arezzo, Foggia, Naples, Terni
2025-03-13
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
60
Rome
2025-03-11
Recruiting
Pfizer
Phase 3
723
Avezzano, Rome, Bologna, Florence, Milan, Pavia, Roma
2025-03-11
Recruiting
A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)
NCT06833073Urinary Bladder Neoplasms, Non-Muscle Invasive Bladder Neoplasms, Carcinoma in Situ
DrugIntismeran autogene
Merck Sharp & Dohme LLC
Phase 2
308
Milan, Rome, Arezzo, Roma
2025-03-11
Recruiting
A Twenty-years' Experience in Pituitary Disease.
NCT06973824Pituitary Adenoma, Pituitary Cancer, Pituitary Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,600
Rome
2025-03-10
Recruiting
AbbVie
Phase 1/2
252
Meldola, Milan, Rome, Orbassano, Ancona, Bologna
2025-03-06
Recruiting
Swedish Orphan Biovitrum
Phase 3
104
Catanzaro, Florence, Milan, Naples, Parma, Rome, Rozzano, Vicenza
2025-03-06
By invitation
Impact of Orthopedic Surgery on Workers' Sleep
NCT06854913Shoulder Musculoskeletal Disorders
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
30
Rome
2025-03-03
Recruiting
Takeda
Phase 3
1,088
Torrette, Rome, Milan, Rozzano, Padova, Florence, Pisa
2025-03-03
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Rome
2025-03-01
Recruiting
Serratus Posterior Superior Intercostal Plane Block in Robotic-Assisted Thymectomy
NCT06545409RATS Surgery, Thymectomy, Locoregional Anesthesia, Postoperative Pain Management
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
28
Rome
2025-03-01
Not yet open
Cervical TsDCS on Stroke Patients
NCT06826274Functional Recovery, Motor Rehabilitation
IRCCS San Raffaele Roma
Not applicable
40
Rome
2025-03
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
300
Rome
2025-02-28
Recruiting
Summit Therapeutics
Phase 3
780
Rome, Bari, Bergamo, Milan, Orbassano, Parma, Peschiera del Garda
2025-02-27
Recruiting
Takeda
Phase 3
171
Naples, Rome, Catania, Bologna, Milan, Monza, Novara, Torino
2025-02-27
Recruiting
Amgen
Phase 3
844
Udine, Rome, Milan, Turin, Verona, Pisa, Reggio Emilia
2025-02-25
Recruiting
Bristol-Myers Squibb
Phase 3
530
Naples, Milan, Rome, Perugia, Peschiera del Garda, Bologna
2025-02-25
Recruiting
Menarini Group
Phase 2
44
Bari, Bologna, Genoa, Parma, Rome, Torino
2025-02-18
Active, closed
Shared Interactive Book Reading in Preschool Children With Neurodevelopmental Disorders: Effects on Language Development and Reading Habits
NCT06852989Neurodevelopmental Disorders, Autism Spectrum Disorder, Intellectual Disabilities, Language Disorders in Children
Fondazione Don Carlo Gnocchi ETS
Observational
53
Rome
2025-02-13
Recruiting
AbbVie
Phase 3
420
Milan, Rome
2025-02-13
Recruiting
Lupin Ltd.
Phase 3
176
Rome
2025-02-13
By invitation
Longboard Pharmaceuticals
Phase 3
324
Florence, Genoa, Milan, Pavia, Rome, Verona
2025-02-12
Active, closed
Sanofi
Phase 3
231
Cona, Florence, Genoa, Milan, Padua, Rome, Bologna
2025-02-12
Recruiting
Catholic University of the Sacred Heart
Not applicable
120
Rome
2025-02-10
Active, closed
AbbVie
Phase 3
468
Florence, Milan, Naples, Rome, Latina, Pavia, Perugia, Udine
2025-02-10
Recruiting
Catholic University of the Sacred Heart
Observational
1,202
Rome
2025-02-07
Recruiting
Takeda
Phase 2
96
Pozzilli, Rome, Verona, Bologna
2025-02-07
Recruiting
IRCCS San Raffaele Roma
Not applicable
130
Rome, San Vito sullo Ionio, Costa Masnaga, Fiorenzuola d'Arda, Passignano sul Trasimeno, Ummbertide, Bergamo, Catanzaro
2025-02-06
Recruiting
Low Impact Laparoscopy In Bariatric Surgery
NCT07119437Obesity, Morbid
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
128
Rome
2025-02-04
Recruiting
Genetic and Immunity in Heart Failure
NCT06758128Heart Failure
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
215
San Giovanni Rotondo, Rome
2025-02-04
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
30
Rome
2025-02-04
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Rome
2025-02-01
Recruiting
Impulse Dynamics
Observational
200
Rome, Naples
2025-02-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
150
Rome
2025-02-01
Recruiting
Alimentiv Inc.
Not applicable
378
Castellana Grotte, Florence, Milan, Roma, Rome, San Giovanni Rotondo
2025-02-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
56
Rome
2025-02-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
180
Rome
2025-02-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
120
Rome
2025-02
Recruiting
AbbVie
Observational
1,200
Rozzano, Milan, Naples, Rome, Ancona, Brescia, Campobasso, Catania
2025-01-31
Recruiting
University of Rome Tor Vergata
Not applicable
30
Rome
2025-01-31
Recruiting
Regina Elena Cancer Institute
Observational
20
Rome
2025-01-29
Active, closed
Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)
NCT06710132Solid Tumors, Gastric Cancer, Non-Small Cell Lung Cancer (NSCLC), Pancreatic Cancer
DrugM9140
EMD Serono Research & Development Institute, Inc.
Phase 1/2
184
Rome, Ancona, Milan, Naples, Padova, Pisa, Reggio Emilia, Roma
2025-01-29
Recruiting
Floriana Costanzo
Not applicable
36
Rome
2025-01-27
Recruiting
IRCCS Policlinico S. Donato
Not applicable
30,000
Milan, Ancona, Genova, Naples, Palermo, Pavia, Pozzilli, Rome
2025-01-22
Recruiting
Takeda
Phase 3
70
Messina, Milan, Pescara, Rome
2025-01-22
Active, closed
Human Amniotic Mesenchymal Cell Secretome for Neurodegeneration and Neuroinflammation
NCT06551649Amyotrophic Lateral Sclerosis, Multiple Sclerosis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
60
Roma, Rome
2025-01-17
Recruiting
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
NCT06680830Parkinson Disease, Parkinson, Idiopathic Parkinson Disease, Early Parkinson Disease (Early PD)
Neuron23 Inc.
Phase 2
150
Milan, Naples, Padua, Pisa, Rome
2025-01-17
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
252
Rome
2025-01-16
Recruiting
Fondazione Italiana Sclerosi Multipla
Not applicable
30
Rome, Genoa
2025-01-15
Recruiting
ETOP IBCSG Partners Foundation
Phase 3
290
Alessandria, Padova, Perugia, Rome, Siena, Verona
2025-01-15
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
50
Rome
2025-01-15
Active, closed
Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)
NCT06700343Relapsing-remitting Multiple Sclerosis (RRMS)
DrugOcrelizumab
Amgen
Phase 3
152
Bologna, Milan, Naples, Rome
2025-01-13
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
40
Rome
2025-01-13
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase 3
108
Rome
2025-01-10
Active, closed
Campus Bio-Medico University
Phase 4
16
Rome
2025-01-10
Recruiting
DDR Genes Alteration and Response to Platinum-based Chemotherapy in Advanced Urothelial Cancer.
NCT06820255Bladder (Urothelial, Transitional Cell) Cancer Metastatic or Unresectable, Upper Tract Urothelial Cancer
DrugGemcitabine
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase 4
135
Rome
2025-01-07
Active, closed
Pfizer
Phase 3
1,035
Bologna, Meldola(FC), Rome, Florence, Milan, Novara, Padova, Roma
2025-01-06
Recruiting
I.R.C.C.S. Fondazione Santa Lucia
Not applicable
60
Rome, Messina
2025-01-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
4,900
Rome
2025-01-01
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
38
Rome
2025-01-01
By invitation
Contrast Enhanced Mammography in the Evaluation of Cancer of Unknown Primary Syndrome
NCT06843096Breast Cancer Diagnosis, Breast Cancer Prevention
Graziella di Grezia
Observational
350
Rome
2025-01-01
Recruiting
University Children's Hospital, Zurich
Not applicable
40
Rome
2025-01
Active, closed
Palatal Mucosa Wound Healing Following Antimicrobial Gel Application
NCT06737653Wound Healing, Palate; Wound, Hyaluronic Acid
University of Roma La Sapienza
Not applicable
13
Rome
2024-12-22
Recruiting
Using Glialia for Treating Persistent Perceptual Postural Dizziness
NCT06741358Persistent Postural Perceptual Dizziness
I.R.C.C.S. Fondazione Santa Lucia
Phase 4
30
Rome
2024-12-21
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
152
Rome
2024-12-20
Active, closed
Trustworthy Artificial Intelligence for Improvement of Stroke Outcomes
NCT06710028Stroke, Acute, Stroke, Ischemic, Stroke
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Rome
2024-12-18
Recruiting
Study of Ultomiris® (Ravulizumab) Safety in Pregnancy
NCT06312644Ultomiris-exposed Pregnant/ Postpartum, Pregnancy, Paroxysmal Nocturnal Hemoglobinuria (PNH), Atypical Hemolytic Uremic Syndrome (aHUS)
DrugUltomiris
Alexion Pharmaceuticals, Inc.
Observational
75
Rome
2024-12-16
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
90
Rome
2024-12-16
Recruiting
Biogen
Observational
300
Conegliano, Milan, Rome
2024-12-12
Active, closed
Hoffmann-La Roche
Phase 3
350
Rome, Brescia, Milan, Monza MI, Rozzano (MI), Negrar
2024-12-11
Active, closed
Sanofi
Phase 2
260
Milan, Rozzano, Padua, Rome, Pisa
2024-12-10
Active, closed
AI-Powered ECG Detecting Culprit Vessel Blood Flow Abnormality in ACS
NCT06528821Acute Coronary Syndrome, STEMI, Coronary Occlusion, Coronary Syndrome
Powerful Medical
Observational
800
Chieti, Rome
2024-12-10
Active, closed
Kumquat Biosciences Inc.
Phase 1
13
Bologna, Rome, Milan
2024-12-09
Active, closed
Hoffmann-La Roche
Phase 2
62
Bari, Rome, Orbassano, Verona
2024-12-09
Recruiting
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
108
Rome
2024-12-04
Recruiting
University Hospital Freiburg
Not applicable
20,000
Rome, Ferrara, Modena, Roma
2024-12-03
Recruiting
Visual Rehabilitation and Depression in Visually Impaired Patients With AMD
NCT06906003AMD - Age-Related Macular Degeneration, Anxiety, Depression Disorders
Fondazione G.B. Bietti, IRCCS
Observational
22
Rome
2024-12-02
Recruiting
Next Generation Sequencing Analysis of Patients with Spontaneous Dissection of Cervical Arteries
NCT06862063Dissection Carotid Artery, Dissection Arterial, Dissecting Aneurysm
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
145
Rome
2024-12-01
Not yet open
Pentabiocel in Pediatric IBS
NCT06720805Irritable Bowel Syndrome (IBS), Pediatrics
University of Roma La Sapienza
Not applicable
56
Milan, Rome
2024-12-01
Active, closed
The Future Management of Patients With Neoplasms of the Gastro-intestinal Tract
NCT06728358Pancreatic Adenocarcinoma, Cholangiocarcinoma, Colon Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
300
Rome
2024-12-01
Not yet open
University of Roma La Sapienza
Not applicable
32
Rome
2024-12
Recruiting
Drug Management in Heart Failure
NCT06915584Heart Failure
IRCCS San Raffaele Roma
Observational
450
Rome
2024-11-30
By invitation
Imaging and Gait Analysis in FSHD Patients
NCT07164937FSHD - Facioscapulohumeral Muscular Dystrophy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
40
Rome
2024-11-30
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
108
Rome
2024-11-30
Recruiting
Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases
NCT06685042Lupus Erythematosus, Systemic, System; Sclerosis, ANCA Associated Vasculitis, Dermatomyositis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase 1/2
8
Rome
2024-11-29
Recruiting
AstraZeneca
Phase 3
1,160
Florence, Legnano, Livorno, Monza, Peschiera del Garda, Rome
2024-11-27
Active, closed
VT ART Consortium: Radioablation for Ventricular Tachycardia
NCT06922214Ventricular Tachycardia (VT)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
52
Rome
2024-11-26
Active, closed
AbbVie
Observational
1,314
Milan, Naples, Turin, Rome, Ancona, Bari, Catanzaro, Pavia
2024-11-26
Recruiting
Multicenter Analysis of Different Approaches in Segmentectomies in Early-stage Lung Cancer
NCT06737107Early Stage Lung Cancer (I and II), Non-Small Cell Lung Cancer
Scientific Institute San Raffaele
Observational
472
Rozzano, Milan, Rome
2024-11-26
Active, closed
Genmab
Phase 3
191
Monza, Rozzano, Naples, Aviano, Rome, Orbassano, Bergamo, Candiolo
2024-11-25
Recruiting
Idorsia Pharmaceuticals Ltd.
Observational
785
Rome
2024-11-21
Recruiting
University of Rome Tor Vergata
Observational
25
Rome
2024-11-20
Recruiting
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
NCT06690775Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer, Endometrioid Ovarian Cancer
DrugsTORL-1-23·Pegfilgrastim
TORL Biotherapeutics, LLC
Phase 2
230
Bari, Milan, Prato, Rome
2024-11-20
Active, closed
Daiichi Sankyo
Phase 3
700
Bari, Brescia, Meldola, Milan, Novara, Palermo, Roma, Rome
2024-11-19
Recruiting
Takeda
Phase 3
30
Genova, Messina, Naples, Rome, Trieste
2024-11-19
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
20
Roma, Rome
2024-11-15
Active, closed
Pfizer
Phase 3
200
L’Aquila, Bari, Milan, Rome, Brescia, Latina, Pavia, Roma
2024-11-15
Recruiting
Meyer Children's Hospital IRCCS
Not applicable
700
Florence, Rome
2024-11-15
By invitation
Mario Stirpe
Observational
400
Milan, Novara, Rome, Sassari, Genoa
2024-11-14
Recruiting
THE-0504 in Patients With Solid Tumors
NCT07646106Small Cell Lung Cancer (SCLC), Colorectal Carcinoma (CRC), Gastric Cancer (GC), Triple -Negative Breast Cancer
Thena Biotech S.r.l.
Phase 1
30
Rome
2024-11-13
Recruiting
Boehringer Ingelheim
Phase 3
1,590
Bologna, Foggia, Milan, Modena, Palermo, Rome, Rozzano, Torino
2024-11-12
Active, closed
Longboard Pharmaceuticals
Phase 3
367
Florence, Genoa, Milan, Pavia, Rome, Verona
2024-11-11
Recruiting
Janssen Research & Development, LLC
Phase 3
39
Milan, Rome
2024-11-11
Active, closed
Sanofi
Phase 2
556
Torette, Monserrato, Cona, Genoa, Milan, Rozzano, Rome, Bergamo
2024-11-07
Recruiting
Genomic Profiling of Genetic and Rare Diseases
NCT06926127Rare Diseases, Genetic Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
1,500
Rome
2024-11-05
Recruiting
Fertility And Sexual Function In CAH: CALLIOPE
NCT07099456Congenital Adrenal Hyperplasia (CAH)
University of Roma La Sapienza
Observational
50
Rome
2024-11-01
Recruiting
Regeneron Pharmaceuticals
Phase 3
975
Rome, Milan, Florence, Ancona
2024-10-30
Recruiting
Société des Produits Nestlé (SPN)
Not applicable
104
Naples, Parma, Pisa, Rome, Turin
2024-10-25
Active, closed
Eli Lilly and Company
Phase 2
45
Milan, Naples, Rome
2024-10-25
Recruiting
Regina Elena Cancer Institute
Not applicable
30
Rome
2024-10-23
Active, closed
Regina Elena Cancer Institute
Not applicable
90
Rome
2024-10-23
Recruiting
Pfizer
Phase 3
900
Meldola, Rome, Rozzano, Cremona, Milan, Naples, Terni, Trento
2024-10-22
Active, closed
Pfizer
Phase 3
600
Meldola, Rome, Milan
2024-10-21
Recruiting
Merck Sharp & Dohme LLC
Phase 3
680
Catanzaro, Ravenna, Rome, Milan, Naples, Padova, Verona
2024-10-21
Recruiting
Study of ATX-01 in Participants With DM1
NCT06300307Myotonic Dystrophy 1
ARTHEx Biotech S.L.
Phase 1/2
56
Milan, Rome
2024-10-15
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
200
Roma, Rome
2024-10-15
Recruiting
Boehringer Ingelheim
Phase 3
1,800
Bologna, Foggia, Milan, Modena, Novara, Palermo, Rome, Rozzano
2024-10-14
Recruiting
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
197
Rome
2024-10-14
Active, closed
Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)
NCT06553768Cholestatic Liver Disease (Except ALGS, PFIC, PBC and PSC)
DrugMaralixibat
Mirum Pharmaceuticals, Inc.
Phase 3
90
Bergamo, Palermo, Rome
2024-10-14
Active, closed
Incyte Corporation
Phase 2
130
Bergamo, Bologna, Milan, Rome, Rozzano, Torino
2024-10-11
Recruiting
Boehringer Ingelheim
Phase 2
588
Ancona, Aviano (PN), Meldola (FC), Milan, Naples, Rome
2024-10-11
Active, closed
A 3D Bioprinted Hormone-producing Model for BRCA Mutated Patients After Risk Reducing Surgery: the DISC-OVARY Trial
NCT06497270BRCA Mutation, Estrogen Deficiency, Surgical Menopause, Menopause Related Conditions
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
3
Rome
2024-10-10
Active, closed
Incyte Corporation
Phase 3
349
Catania, Chieti, L’Aquila, Milan, Naples, Perugia, Pisa, Rome
2024-10-10
Active, closed
SynOx Therapeutics Limited
Phase 3
128
Rome, Candiolo, Palermo, Bologna, Milan
2024-10-09
Recruiting
Bristol-Myers Squibb
Phase 3
1,000
Bari, Ravenna, Monza, Milan, Naples, Rome, Peschiera del Garda, Bergamo
2024-10-07
Recruiting
Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)
NCT05947955Acute Respiratory Distress Syndrome, Infections
BioAegis Therapeutics Inc.
Phase 2
600
Brescia, Rome
2024-10-03
Recruiting
Ferring Pharmaceuticals
Phase 3
454
Rome, Rozzano
2024-10-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
60
Rome
2024-10-01
Active, closed
I.R.C.C.S. Fondazione Santa Lucia
Phase 4
62
Rome
2024-10-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
700
Milan, Rome
2024-10
Recruiting
Scientific Institute San Raffaele
Observational
140
Rozzano, Milan, Rome
2024-09-30
By invitation
Sanofi
Phase 2
900
Rome
2024-09-30
Recruiting
Regina Elena Cancer Institute
Not applicable
98
Rome
2024-09-26
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
406
Salerno, Rome, Brescia, Milan, Ponderano (Biella), Roma
2024-09-26
Active, closed
Longboard Pharmaceuticals
Phase 3
96
Florence, Genoa, Pavia, Rome, Verona
2024-09-25
Active, closed
Merus B.V.
Phase 3
699
Ancona, Brescia, Cagliari, Meldola, Milan, Naples, Rome, Rozzano
2024-09-25
Active, closed
Hoffmann-La Roche
Phase 3
338
Bari, Parma, Rome, Genoa, Sassari, Florence, Pisa, Padova
2024-09-23
Active, closed
Cerevance
Phase 3
330
Cassino, Padova, Rome
2024-09-20
Active, closed
Regeneron Pharmaceuticals
Phase 2
151
Cuneo, Ferrara, Milan, Naples, Novara, Pisa, Rome, Taormina
2024-09-18
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Roma, Rome
2024-09-17
Active, closed
Dianthus Therapeutics
Phase 2
46
Rome
2024-09-17
Active, closed
Hoffmann-La Roche
Phase 3
400
Matera, Naples, Rome, Pavia, Rho
2024-09-17
Recruiting
University of Roma La Sapienza
Not applicable
400
Rome
2024-09-17
Not yet open
UNDERSTANDING the RAREST GYNECOLOGICAL CANCERS: a MULTI -OMICS PLATFORM for IMPROVED PATIENTS MANAGEMENT
NCT06582108Uterine Sarcoma, Vulvar Cancer, Non Epithelial Ovarian Cancers (NEOC)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
190
Rome
2024-09-15
Recruiting
Clinical-ultrasonographic Assessment of Pulmonary Emphysema
NCT06533371Emphysema, Pulmonary Emphysema
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
1,628
Acquaviva delle Fonti, Naples, Rome, Trento
2024-09-04
Recruiting
AbbVie
Phase 2
590
Monserrato, San Giovanni Rotondo, Rozzano, Milan, Rome, Turin, Negrar, Catanzaro
2024-09-04
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
20
Rome
2024-09-04
Active, closed
How Epigenetic Changes in hMLH1 Connect Lab Research With Diagnosis in Gastric Cancer
NCT06982768Gastrectomy for Gastric Cancer, Gastrectomy, MLH1 Gene Mutation, Gastric Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
245
Rome
2024-09-01
Active, closed
Servier Bio-Innovation LLC
Phase 1/2
48
Campania, Milan, Pisa, Rome, Verona
2024-08-31
Active, closed
Alpine Immune Sciences Inc, A Subsidiary of Vertex
Phase 3
605
Bari, Genova, Modena, Pavia, Rome
2024-08-30
Active, closed
Celgene
Phase 2
95
Rome, Rozzano, Bologna, Naples
2024-08-30
Active, closed
Phase IIa Study Evaluating AZD7798 in Crohn's Disease
NCT06450197Moderate to Severe Crohn's Disease
DrugAZD7798
AstraZeneca
Phase 2
120
Milan, Roma, Rome
2024-08-28
Recruiting
Observational Study of Venus P-Valve
NCT05835349Right Ventricular Outflow Tract Dysfunction
Venus MedTech (HangZhou) Inc.
Observational
200
Rome, Milan
2024-08-26
Active, closed
argenx
Phase 2
3
Pisa, Rome
2024-08-20
Recruiting
AbbVie
Phase 3
675
Rome, Bologna
2024-08-19
Recruiting
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
NCT06395103B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma, Burkitt Lymphoma, Neuroblastoma
DrugZilovertamab vedotin
Merck Sharp & Dohme LLC
Phase 1/2
90
Milan, Rome, Torino
2024-08-16
Recruiting
AbbVie
Phase 3
110
San Giovanni Rotondo, Rome, Messina, Milan
2024-08-08
Active, closed
EyeBiotech Ltd.
Phase 2/3
984
Bologna, Florence, Milan, Roma, Rome, Udine
2024-08-07
Active, closed
Pfizer
Observational
450
Bari, Rozzano, Bologna, Catania, Roma, Rome
2024-08-07
Recruiting
Regina Elena Cancer Institute
Observational
100
Rome
2024-08-06
Active, closed
Merck Sharp & Dohme LLC
Phase 3
3,000
Rome, Milan, Turin, Catania
2024-08-05
Recruiting
AstraZeneca
Phase 3
788
Bergamo, Bologna, Milan, Modena, Naples, Padova, Reggio Emilia, Rome
2024-08-01
By invitation
AOP Orphan Pharmaceuticals AG
Observational
110
Rome
2024-07-31
Recruiting
NovoCure GmbH
Phase 3
734
Alessandria, Bergamo, Ferrara, Meldola, Pesaro, Roma, Rome, Siena
2024-07-31
By invitation
Biohaven Therapeutics Ltd.
Phase 2
660
Chieti, Catanzaro, Naples, Bologna, Rome, Genoa, Milan, Pavia
2024-07-30
Active, closed
Annexon, Inc.
Phase 3
659
Florence, Milan, Roma, Rome
2024-07-30
Recruiting
Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy
NCT06475261Oxygen Deficiency, Acute Kidney Injury, Ovarian Carcinoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
50
Rome
2024-07-27
Recruiting
Regina Elena Cancer Institute
Observational
150
Rome
2024-07-24
Recruiting
Regina Elena Cancer Institute
Observational
40
Rome
2024-07-24
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
36
Rome
2024-07-20
Recruiting
Caring for Frail Patients Through Vaccination
NCT06127563Vaccination Uptake
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,500
Rome
2024-07-17
Recruiting
Vor Biopharma
Phase 3
180
San Giovanni Rotondo, Naples, Cefalù, Pavia, Rome
2024-07-17
Recruiting
University of Roma La Sapienza
Not applicable
40
Rome
2024-07-17
Active, closed
A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work
NCT06290128Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic
DrugRiliprubart
Sanofi
Phase 3
109
Milan, Rozzano, Rome, Messina, Palermo, Pavia, Pisa
2024-07-12
Recruiting
University of Bologna
Observational
120
Bologna, Catania, Milan, Padova, Palermo, Rome, Siena, Turin
2024-07-09
Recruiting
AbbVie
Phase 3
40
Florence, Milan, Rome
2024-07-08
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
30
Rome
2024-06-30
Active, closed
AstraZeneca
Phase 3
339
Brescia, Cona, Florence, Milan, Naples, Reggio Emilia, Roma, Rome
2024-06-29
Active, closed
AbbVie
Phase 3
1,400
Cona, Florence, Rozzano, Naples, Rome, Catania, Milan
2024-06-27
Recruiting
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Phase 3
264
Bergamo, Bologna, Genova, Milan, Pavia, Rome, Treviso
2024-06-25
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,530
Naples, Misterbianco, Meldola (FC), Aviano, Rome, Brescia, Milan, Monza
2024-06-24
Recruiting
Regina Elena Cancer Institute
Observational
40
Rome
2024-06-20
Active, closed
Celgene
Phase 3
850
Ravenna, Rome, Palermo, Novara
2024-06-19
Recruiting
H. Lundbeck A/S
Phase 2
18
Padova, Pisa, Messina, Rome, Torino
2024-06-19
Active, closed
Ivy Brain Tumor Center
Phase 3
450
Bologna, Florence, Milan, Rozzano, Naples, Padova, Rome, Torino
2024-06-19
Recruiting
Fondazione Policlinico Universitario Campus Bio-Medico
Phase 4
26
Rome
2024-06-18
Active, closed
BioMarin Pharmaceutical
Phase 3
80
Genoa, Rome
2024-06-17
Recruiting
AbbVie
Phase 3
200
L’Aquila, Rozzano, Rome, Milan
2024-06-14
Recruiting
LEO Pharma
Phase 3
195
Ancona, Brescia, Padova, Roma, Rome
2024-06-10
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
194
Rome
2024-06-10
Recruiting
Merck Sharp & Dohme LLC
Phase 3
851
Naples, Rome, Milan, Monza, Rozzano, Brescia, Genova, Novara
2024-06-10
Active, closed
Exelixis
Phase 2/3
600
Candiolo, Brescia, Catania, Milan, Naples, Rome, Rozzano, Verona
2024-06-07
Active, closed
Janssen Research & Development, LLC
Phase 1
108
Ancona, Bergamo, Brescia, Meldola, Pisa, Rome
2024-06-07
Active, closed
GlaxoSmithKline
Phase 4
303
Brescia, Ferrara, Milan, Pisa, Reggio Emilia, Rome, Rozzano
2024-06-06
By invitation
Evaluation of Respiratory Mechanics in Supine and PARK-bench Positions (SPARK)
NCT06448988Ventilation Therapy; Complications, Ventilator-Induced Lung Injury
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
22
Rome
2024-06-06
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,200
Bari, Monserrato, Rome, Milan, Rozzano, Naples, Turin, Pontedera
2024-06-05
Recruiting
Regina Elena Cancer Institute
Observational
256
Rome
2024-06-04
Active, closed
Kumquat Biosciences Inc.
Phase 1
92
Rome, Naples
2024-06-03
Recruiting
Risk of Falling and Cardiac Rehabilitation
NCT06908759Risk of Falling, Elderly (People Aged 65 or More), Cardiovascular Diseases
IRCCS San Raffaele Roma
Not applicable
150
Rome
2024-05-31
Active, closed
ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer
NCT06328738HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2 Positive Solid Tumors, HER2 Amplification
DrugsELVN-002·Eribulin·Leucovorin·Trastuzumab
Enliven Therapeutics
Phase 1
275
Catanzaro, Milan, Monza, Pisa, Reggio Emilia, Rome
2024-05-30
Recruiting
Regina Elena Cancer Institute
Observational
10
Rome
2024-05-25
Recruiting
Elisa Giannetta
Observational
150
Rome
2024-05-24
Recruiting
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
NCT06419374Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
DrugPegozafermin
89bio, Inc.
Phase 3
762
Bergamo, Foggia, Milan, Novara, Palermo, Roma, Rome, Rozzano
2024-05-24
Recruiting
Merck Sharp & Dohme LLC
Phase 3
348
Naples, Ravenna, Aviano, Rome, Milan, Livorno, Padova
2024-05-24
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
220
Rome, Milan, Rozzano, Verona
2024-05-20
Recruiting
IRCCS San Raffaele Roma
Not applicable
70
Cassino, Rome, Sulmona
2024-05-19
Active, closed
AbbVie
Phase 3
421
Legnano, Turin, Rome, Ancona, Catania
2024-05-19
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
250
Rome
2024-05-16
Active, closed
Biohaven Therapeutics Ltd.
Phase 2/3
390
Chieti, Catanzaro, Naples, Bologna, Rome, Genoa, Milan, Pavia
2024-05-13
Active, closed
Sanofi
Phase 3
1,541
Milan, Rozzano, Rome, Bologna, Catania, L’Aquila, Pisa, Vicenza
2024-05-08
Recruiting
Solid Biosciences Inc.
Phase 1/2
60
Rome
2024-05-06
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
129
Rome
2024-05-06
Recruiting
University of Rome G. Marconi
Not applicable
114
Bologna, Rome
2024-05-06
Active, closed
Merck Sharp & Dohme LLC
Phase 3
450
Naples, Rome, Milan, Pisa
2024-05-03
Active, closed
Hoffmann-La Roche
Phase 2
256
Tricase (LE), Rome, Milan, Pavia
2024-05-02
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
1,600
Rome
2024-05-01
Recruiting
Eli Lilly and Company
Phase 3
510
Florence, Milan, Naples, Padova, Pisa, Rome, Vimercate
2024-04-29
Recruiting
Bambino Gesù Hospital and Research Institute
Phase 1
24
Rome
2024-04-28
Recruiting
CD7-CAR-T Cells in Pediatric Relapsed/Refractory CD7+ T-ALL/LL
NCT06064903T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Bambino Gesù Hospital and Research Institute
Phase 1/2
26
Rome
2024-04-21
Recruiting
MALE Mamm Organoids
NCT06786663Breast Neoplasms, Male
Regina Elena Cancer Institute
Observational
7
Rome
2024-04-19
Active, closed
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
NCT06372145Relapsing Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, Progressive Relapsing Multiple Sclerosis
DrugTeriflunomide
Sanofi
Phase 3
2,500
Pozzilli, Milan, Rome, Florence, Bergamo, Cagliari, Catania, Chieti
2024-04-16
Recruiting
Daiichi Sankyo
Phase 1/2
680
Candiolo, Milan, Naples, Rome, Rozzano
2024-04-10
Active, closed
Merck Sharp & Dohme LLC
Phase 2
272
Rome, Milan, Florence, Parma
2024-04-10
Active, closed
Amgen
Phase 3
434
Reggio Emilia, Udine, Rome, Milan, Novara, Florence, Verona, Catania
2024-04-08
Active, closed
TWi Biotechnology, Inc.
Phase 2/3
80
Milan, Modena, Rome
2024-04-04
Recruiting
Merck Sharp & Dohme LLC
Phase 3
780
Misterbianco, Meldola, Milan, Monza, Rome, Florence, Bergamo, Genova
2024-04-03
Recruiting
Hoffmann-La Roche
Phase 4
320
Meldola, Modena, Aviano (PN), Rome, Milan
2024-04-02
Recruiting
Patients With Interstitial Lung Disease
NCT06645977Interstitial Lung Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,200
Rome
2024-04-01
Recruiting
Corbus Pharmaceuticals Inc.
Phase 1/2
348
Florence, Milan, Rome, Verona
2024-04-01
Active, closed
Takeda
Phase 2
213
Bologna, Milan, Palermo, Rome, Rozzano
2024-03-29
Active, closed
Merck Sharp & Dohme LLC
Phase 1/2
230
Rome, Genoa, Milan, Naples
2024-03-28
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
120
Rome
2024-03-28
Recruiting
Italfarmaco
Phase 3
220
Bari, Reggio Calabria, Bologna, Meldola, Reggio Emilia, Udine, Rome, Bergamo
2024-03-26
Active, closed
AbbVie
Phase 2
156
Monserrato, Rome, Negrar
2024-03-23
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Italian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 11 October 2026. https://priyalifescience.com/clinical-trials-italy/city/rome

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Italy and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,791 studies in total at the last sync on 11 Oct 2026, 03:19 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 968 of those studies with a site in Rome.

How many clinical trials are recruiting in Rome?

510 of the 968 studies on this page are recruiting new participants as of the 11 Oct 2026, 03:19 UTC sync. A further 61 have not yet opened recruitment, 369 are active but closed to new participants, and 28 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Rome), 968 studies
PhaseStudiesRecruitingShare
Phase 331913633%
Observational25516326.3%
Not applicable1539515.8%
Phase 21195312.3%
Phase 1/249315.1%
Phase 2/330123.1%
Phase 12372.4%
Phase 418121.9%
Early Phase 1210.2%

Most active sponsors

Lead sponsors with the most studies (Rome)
Lead sponsorStudiesRecruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS171102
Hoffmann-La Roche7325
AbbVie5623
Merck Sharp & Dohme LLC4018
Sanofi308
Regina Elena Cancer Institute2923
Pfizer199
AstraZeneca178
Takeda1715
Bristol-Myers Squibb158
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.