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Active, not recruiting Observational

Observational Study Regarding the Combination of Fluoropyrimidine and Bevacizumab in Patients With mCRC

NCT07494578 · tracked via the Priya Life Science Italy tracker
Phase
Observational
Started
2025-07-01
Last updated
2026-03-27

Condition(s) studied

Colon Cancer Metastatic

Investigational drug(s) / intervention(s)

Fluoropyrimidine →

Fluoropyrimidine: Treatment with fluoropyrimidines and bevacizumab

Study summary

This study will enroll patients with metastatic colorectal cancer treated with the combination of Trifluridine/Tipiracile and Bevacizumab across 15 italian centers.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age ≥18 years; * ECOG PS 0-2; * Histologic diagnosis of colorectal cancer; * Treatment with fluoropyrimidine plus bevacizumab. Exclusion Criteria: * ECOG PS ≥3; * Absence of histologic diagnosis.

Primary outcome measure(s)

  • Overall Survival — up to 30 months from the date of treatments' start
    Time from start of the treatment to death from any cause up to 30 months from the date of treatments' start.
  • Progression-free survival — up to 30 months from the date of treatments' start
    time from the start of the treatment to disease progression or death from any cause, whichever occurred first, up to 30 months from the date of treatments' start.

Trial sites (1)

FacilityCityRegionStatus
Policlinico Universitario Agostino Gemelli Rome Lazio
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07494578 on ClinicalTrials.gov ↗ ← All trials in Italy