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Clinical Trials in Italy / NCT06882954
Recruiting Observational

The Management of Asymptomatic Carotid Stenosis

NCT06882954 · tracked via the Priya Life Science Italy tracker
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase
Observational
Started
2019-01-01
Last updated
2025-03-19

Condition(s) studied

Carotid Artery DiseasesCarotid Stenosis

Study summary

Carotid stenosis are asymptomatic if no hemispheric or retinal symptoms have appeared in the 6 months preceding the discovery of the stenosis. Asymptomatic carotid stenosis (ACS) accounts for about ¾ of all carotid lesions. The goal of treating carotid stenosis is to prevent a stroke. While carotid surgery is recommended in the elderly patients in cases of symptomatic carotid stenosis, that of ACS in patients over 75 years old, even when tight, remains subject to many controversies. Indeed, the debate, concerning the benefit to be expected from a surgical procedure or a possible angioplasty procedure, is not yet closed. The aim of our study, through a retrospective evaluation of the results of all consecutive carotid endarterectomy (CEA) and stenting in the participating center.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Asymptomatic carotid stenosis * Patient with degree of carotid stenosis greater than 80% measured by the maximum systolic velocity at the site of the stenosis which must have been greater than 250 cm/s * Ultrasound characteristics of a possibly unstable plaque Exclusion Criteria: * Symptomatic carotid artery stenosis

Primary outcome measure(s)

  • Stroke rate — Through study completion, an average of 1 year
    Rate of stroke after the procedure

Trial sites (1)

FacilityCityRegionStatus
Fondazione Policlinico Universitario A. Gemelli IRCCS Roma RM Recruiting

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Other trials for the same condition

Hemodynamic Monitoring Carotid Surgery Recruiting
Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System Active, not recruiting
Multicentric Study on Clopidogrel Resistance in DAPT for CAS (MULTI-RESCLOSA) Recruiting
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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06882954 on ClinicalTrials.gov ↗ ← All trials in Italy