Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive Patients

Inclusion Criteria: * Diagnosis of primary glaucoma (open or closed angle) or secondary glaucoma (pseudoexfoliative or pigmentary) defined by the presence of a glaucomatous defect of the optic nerve and/or a perimetric glaucomatous defect as defined by the European guidelines * Diagnosis of ocular hypertension (defined by the presence of intraocular pressure values≥22 mmHg, optic nerve and visual field examination within normal limits) * No Optic nerve disease and IOP\<21mmHg for healthy subjects * Age\>18 years * Able to read and sing the informed consent form Exclusion Criteria: 1. BCVA \<5/10 2. Previous eye surgery, except glaucoma surgery or removal of cataracts performed more than 6 months prior to enrollment 3. Other pathologies that can cause alterations of the optic nerve or visual field defects 4. Presence of maculopathies 5. Inability to perform visual field tests 6. Opacity of the dioptric media such that it is not possible to perform reliable OCT and OCTA of acceptable quality