Clinical Trials in Italy / NCT07177352
Recruiting
Phase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
NCT07177352 · tracked via the Priya Life Science Italy tracker
Condition(s) studied
Alzheimers Disease
Investigational drug(s) / intervention(s)
No Intervention
No Intervention: Participants will have their blood drawn and cognitive score measured by the ISLT.
Study summary
This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.
Eligibility
Inclusion Criteria:
* Ability and willingness to participate in an interventional clinical study, including meeting key eligibility criteria of linked interventional Roche AD studies (e.g., specific age ranges)
* Ability and willingness to receive information about potential eligibility in an associated interventional Roche AD study
Exclusion Criteria:
* Dependency in basic activities of daily living (bADLs) due to cognitive impairment
* Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted)
* Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD
* History of severe, clinically significant central nervous system trauma
* Any serious medical condition that precludes a participant's safe participation and completion of a clinical study
* For participants with a clinical diagnosis of MCI or mild AD: Previous AD diagnosis based on biomarker confirmation with an approved or validated rule in method (e.g., amyloid PET or cerebrospinal fluid, blood biomarker) is exclusionary
Primary outcome measure(s)
- Concentration of pTau217 in Blood on Day1 — Day 1
- Cognitive score in ISLT on Day 1 — Day 1
Trial sites (229)
| Facility | City | Region | Status |
|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | Recruiting |
| Banner Alzheimer?s Institute | Phoenix | Arizona | Recruiting |
| Banner Sun Health Research Institute | Sun City | Arizona | Recruiting |
| Sun Valley Research Center, Inc. | Imperial | California | Recruiting |
| Irvine Center for Clinical Research | Irvine | California | Recruiting |
| Healthy Brain Clinic | Long Beach | California | Recruiting |
| Inglewood Clinicals | Los Angeles | California | Recruiting |
| Oakland Clinical | Oakland | California | Recruiting |
| Riverside Clinical | Riverside | California | Recruiting |
| Syrentis Clinical Research | Santa Ana | California | Recruiting |
| Cenexel California Neuroscience Research, LLC | Sherman Oaks | California | Recruiting |
| Yale University | New Haven | Connecticut | Recruiting |
| JEM Research LLC | Atlantis | Florida | Recruiting |
| K2 Medical Research-Winter Garden | Clermont | Florida | Recruiting |
| K2 Medical Research - The Villages | Lady Lake | Florida | Recruiting |
| K2 Medical Research, LLC | Maitland | Florida | Recruiting |
| Visionary Investigators Network- Neurology Aventura | Miami | Florida | Recruiting |
| Renstar Medical Research | Ocala | Florida | Recruiting |
| Charter Research - Winter Park/Orlando | Orlando | Florida | Recruiting |
| Conquest Research - Lake Nona | Orlando | Florida | Recruiting |
| Alzheimer's Research and Treatment Center | Stuart | Florida | Recruiting |
| Axiom Brain Health LLC | Tampa | Florida | Recruiting |
| Charter Research - Lady Lake/The Villages | The Villages | Florida | Recruiting |
| Alzheimer?s Research and Treatment Center | Wellington | Florida | Recruiting |
| Conquest Research, LLC | Winter Park | Florida | Recruiting |
| Grady Memorial Hospital | Atlanta | Georgia | Recruiting |
| Alzheimer's Research and Treatment Center - Columbus | Columbus | Georgia | Recruiting |
| Accel Research Sites-NeuroStudies | Decatur | Georgia | Recruiting |
| CenExel iResearch, LLC | Decatur | Georgia | Recruiting |
| Center for Advanced Research & Education | Gainesville | Georgia | Recruiting |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | Recruiting |
| RE:Cognition (Chicago) | Chicago | Illinois | Recruiting |
| Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville | Chicago | Illinois | Recruiting |
| Tandem Clinical Research, LLC | Marrero | Louisiana | Recruiting |
| Adams Clinical Boston | Boston | Massachusetts | Recruiting |
| Boston Center for Memory | Newton | Massachusetts | Recruiting |
| Adams Clinical Watertown | Watertown | Massachusetts | Recruiting |
| Quest Research Institute | Farmington Hills | Michigan | Recruiting |
| Washington University School of MedicineClinical Translational Research Unit | St Louis | Missouri | Recruiting |
| The Cognitive and Research Center of New Jersey | Ridgewood | New Jersey | Recruiting |
+ 189 more sites — see the full list on the official registry below.
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07177352 on ClinicalTrials.gov ↗ ← All trials in Italy