Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)
Condition(s) studied
Investigational drug(s) / intervention(s)
BLU-808: Oral administration
Placebo: Oral administration
Study summary
This is a 2-part, proof-of-concept study to be conducted globally, designed to evaluate the safety, tolerability, clinical activity, pharmacokinetics, and pharmacodynamics of BLU-808, a wild type KIT inhibitor, in participants with CIndU (Part A) or CSU (Part B).
Eligibility
Primary outcome measure(s)
- Part A and Part B: Number of Participants with Treatment-emergent Adverse Events (TEAEs) — Day 1 through Week 16
Trial sites (47)
| Facility | City | Region | Status |
|---|---|---|---|
| Allervie Clinical Research | Birmingham | Alabama | |
| Acuro Research, Inc. | Little Rock | Arkansas | |
| Modena Allergy & Asthma Clinical Research - La Jolla | La Jolla | California | |
| Allergy & Asthma Associates of Southern California | Laguna Niguel | California | |
| Allergy & Asthma Medical Group and Research Center | San Diego | California | |
| Allergy Affiliates Inc. | Bradenton | Florida | |
| University of South Florida | Tampa | Florida | |
| Treasure Valley Medical Research | Boise | Idaho | |
| Endeavor Health | Northbrook | Illinois | |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | |
| Southern Indiana Clinical Trials | New Albany | Indiana | |
| The Indiana Clinical Trials Center | Plainfield | Indiana | |
| Equity Medical - Bowling Green | Bowling Green | Kentucky | |
| Johns Hopkins University | Baltimore | Maryland | |
| Institute For Asthma & Allergy | Wheaton | Maryland | |
| Chesapeake Clinical Research | White Marsh | Maryland | |
| Henry Ford Health | Detroit | Michigan | |
| Mayo Clinic | Rochester | Minnesota | |
| The Clinical Research Center LLC. | St Louis | Missouri | |
| Montana Medical Research, Inc. | Missoula | Montana | |
| Equity Medical (at Cameron Dermatology) - New York | New York | New York | |
| Bernstein Clinical Research Center | Cincinnati | Ohio | |
| Allergy & Clinical Immunology Associates | Pittsburgh | Pennsylvania | |
| National Allergy, Asthma & Urticaria Centers of Charleston | Charleston | South Carolina | |
| Medical University of South Carolina (MUSC) | Charleston | South Carolina | |
| Reveal Research Institute | Dallas | Texas | |
| Austin Institute for Clinical Research | Pflugerville | Texas | |
| Odense University Hospital - Odense | Odense | Denmark | |
| Fraunhofer-Institut fuer Translationale Medizin und Pharmakologie ITMP - Standort Berlin | Berlin | Germany | |
| Universitaetsklinikum Carl Gustav Carus Dresden | Dresden | Germany | |
| Universitaetsklinikum Frankfurt - Klinikum der Johann Wolfgang Goethe Universitaet | Frankfurt am Main | Germany | |
| Medizinische Hochschule Hannover (MHH) | Hanover | Germany | |
| Universitaetsmedizin der Johannes Gutenberg - Universitaet Mainz | Mainz | Germany | |
| Universitaetsklinikum Tuebingen | Tübingen | Germany | |
| Azienda Ospedale - Università Padova | Padova | Italy | |
| Azienda Ospedaliero Universitaria Policlinico Umberto | Rome | Italy | |
| Centro Ricerche Cliniche di Verona s.r.l. | Verona | Italy | |
| Hospital del Mar | Barcelona | Spain | |
| Hospital Universitario Vall d'Hebron | Barcelona | Spain | |
| Hospital Universitari de Bellvitge | Barcelona | Spain |
+ 7 more sites — see the full list on the official registry below.
More Blueprint Medicines Corporation trials in Italy
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06931405 on ClinicalTrials.gov ↗ ← All trials in Italy