Drug Management in Heart Failure

NCT06915584 · tracked via the Priya Life Science Italy tracker

Sponsor

IRCCS San Raffaele Roma

Phase

Observational

Started

2024-11-30

Last updated

2025-04-08

Condition(s) studied

Heart Failure

Study summary

Aim of the proposal is to create an interactive AI-based multicentre prospective database to provide information on how to improve the QoC for pts with HF.This will provide detailed information on pts characteristics,treatment practices, adherence to prescribed guideline-based optimal drug therapy,and outcomes.The database stems from a registry started two years ago,conceived to provide a contemporary snapshot on the adherence to the latest European GGLL for the therapeutic management of pts with HF.The database will be integrated with a specifically designed algorithm that provides an accurate feedback on whether patients are properly treated according to the ESC most recent recommendations.The expected outcomes are:-define non-adherence level to GGLL-based recommendations for treatment of HF;-provide information on initiation, adherence and persistence over time of the recommended treatment;-reduce medical inertia;produce practical implications to reduce morbidity and mortality

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Both gender * Age \>18 years * Signed informed consent for the study * Known diagnosis of heart failure \> 6 months * Recent or ongoing hospitalization for heart failure exacerbation Exclusion Criteria: * Conditions that, in the investigator's judgment, may interfere with the study or contraindicate participation for safety reasons * Concurrent diagnosis of neoplasia * Advanced COPD (FEV1 \<50%) * Advanced valvular heart disease (severe mitral-aortic stenosis-insufficiency requiring cardiac surgery)

Primary outcome measure(s)

create a registry that provides an updated assessment of the pattern of use of treatments recommended by guidelines in order to collect new evidence on compliance with them. Be they European or Italian for the treatment of patients with increased cardiov — from enrollment to the end of observation al 24 months

Trial sites (1)

Facility	City	Region	Status
IRCCs San Raffaele	Rome	RM	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06915584 on ClinicalTrials.gov ↗ ← All trials in Italy