Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability post-stroke. The goal is to construct an integrated individual biomarker algorithm with a high predictive value for outcomes.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* First stroke in the middle cerebral artery territory.
* Ischemic or hemorrhagic stroke (7-30 days post-acute event).
* Upper limb plegia or paresis.
* Both genders, aged \>18 years.
* Ability to provide informed consent by the patient or caregiver/responsible relative.
Exclusion Criteria:
* Previous stroke.
* Stroke in territories other than the middle cerebral artery.
* Inability to provide informed consent.
* Contraindications to TMS or MRI.
* History of cancer in the past two years.
* Presence of other neurological conditions interfering with biomarkers
Primary outcome measure(s)
change in arm Fugl-Meyer score — at T0 (from 14 to 30 days post-stroke), T1 (after 2 months of intensive rehabilitation treatment) and T2 (4-6 months after discharge). assess the predictive power of biomarkers, individually or in combination, on the Fugl-Meyer Upper Limb Motor Scale (FM-UL) score at two months post-rehabilitation admission and at 4-6 months post-discharge
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.
