Clinical Trials in Italy / NCT06826274
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Cervical TsDCS on Stroke Patients
NCT06826274 · tracked via the Priya Life Science Italy tracker
Condition(s) studied
Functional RecoveryMotor Rehabilitation
Investigational drug(s) / intervention(s)
tDCS
tDCS: Transcranial direct current stimulation
Study summary
The present project aims to evaluate the facilitatory modulation of motor responses of the limb upper limb by tsDCS in patients with arm/hand hyposthenia after cerebral ischemia to verify the possible therapeutic benefits that this type of stimulation can induce in terms of of strength, dexterity and effectiveness in acts of daily living.
Eligibility
Group Stroke:
Inclusion criteria:
1. age over 18 years;
2. first ischemic/hemorrhagic stroke (within 30 days of onset);
3. mild-to-moderate stroke (NIHSS scale score\<16).
4. residual function of the upper limb, assessed by the following scales: - MRC of the distal muscles of the upper limb: score between 2 and 4; - NHISS (items 5A and 5B): score between 1 and 3;
5. ability to give informed consent and understand instructions.
Exclusion criteria:
1. severe spasticity (Ashworth Scale score \> 2);
2. severe aphasia;
3. severe neglect;
4. history of disabling neurological disease;
5. history of epilepsy;
6. significant comorbidities;
7. contraindications to tsDCS.
Healthy Group:
Inclusion criteria:
1. age over 18 years;
2. equalized in age with the patient group.
Exclusion criteria:
1. history of stroke progress;
2. history of severe neurological disease.
Primary outcome measure(s)
- improvement of paretic hand performance — through study completion, an average of 1 year
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during Reaching - improvement of paretic hand performance — through study completion, an average of 1 year
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during Grasping - improvement of paretic hand performance — through study completion, an average of 1 year
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during Lifting test - improvement of paretic hand performance — through study completion, an average of 1 year
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level duringthe Nine Hole Peg test - improvement of paretic hand performance — through study completion, an average of 1 year
The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during finger mobility tests
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| IRCCS San Raffaele Roma | Rome | Rome |
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06826274 on ClinicalTrials.gov ↗ ← All trials in Italy