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Updated 26 Aug 2026 · ClinicalTrials.gov

Clinical Trials in Newcastle upon Tyne

← All UK trials

The most recently updated industry-sponsored clinical trials recruiting across the United Kingdom — searchable by condition, sponsor, phase and city. Refreshed daily from the ClinicalTrials.gov registry.

14
Recruiting now
20
Studies tracked
Newcastle upon Tyne
Selected city
Recruiting Phase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)
Regeneron Pharmaceuticals · started 2024-10-30
📍 Liverpool · York · Bristol · London · Newcastle upon Tyne
NCT06541704 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
Rheumatoid Arthritis
Hoffmann-La Roche · started 2025-12-05
📍 Leicester · Doncaster · Newcastle upon Tyne · Barnet
NCT07137598 on ClinicalTrials.gov ↗
Active Phase 1
Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
Neoplasms
Tesaro, Inc. · started 2016-03-07
📍 Newcastle upon Tyne · Aberdeen · London · Manchester · Oxford
NCT02715284 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
Primary Biliary Cholangitis, PBC
Mirum Pharmaceuticals, Inc. · started 2021-09-22
📍 Southampton · Birmingham · Belfast · London · Newcastle upon Tyne
NCT05050136 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
Unresectable Hepatocellular Carcinoma
Hoffmann-La Roche · started 2021-04-26
📍 Birmingham · Liverpool · London · Manchester · Newcastle upon Tyne
NCT04770896 on ClinicalTrials.gov ↗
Active
A Study About Antibody Levels and Biomarkers in the Blood in People With Late-onset Pompe Disease
Pompe Disease (Late-onset)
Astellas Gene Therapies · started 2024-02-01
📍 Cambridge · Newcastle upon Tyne · Salford
NCT06150820 on ClinicalTrials.gov ↗
Active
PASS of Paediatric Patients Initiating Selumetinib
Neurofibromatosis Type 1
AstraZeneca · started 2022-05-23
📍 London · Manchester · Newcastle upon Tyne
NCT05388370 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
Irritable Bowel Syndrome, Constipation
Eli Lilly and Company · started 2026-04-29
📍 Cheadle · Hounslow · Macclesfield · Newcastle upon Tyne · Newquay
NCT07545772 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Eli Lilly and Company · started 2024-04-29
📍 Bristol · Chelsea · Great Yarmouth · London · Newcastle upon Tyne
NCT06338995 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)
Chronic Graft Versus Host Disease
Sanofi · started 2025-12-02
📍 Newcastle upon Tyne · London
NCT07116031 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
BeOne Medicines · started 2025-06-11
📍 Bournemouth · Headington · Leeds · London · Metropolitan Borough of Wirral
NCT06943872 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)
Irritable Bowel Syndrome, Diarrhea
Eli Lilly and Company · started 2026-05-06
📍 Cheadle · Hounslow · Macclesfield · Newcastle upon Tyne · Newquay
NCT07545759 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a)
Eli Lilly and Company · started 2024-03-05
📍 Blackpool · Bristol · Cheadle · Enfield · Glasgow
NCT06292013 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Metabolic Dysfunction-Associated Steatotic Liver Disease
Eli Lilly and Company · started 2025-10-15
📍 Aberdeen · Clifton · Enfield · Glasgow · Ipswich
NCT07165028 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Systemic Lupus Erythematosus, Active Refractory Rheumatoid Arthritis
Amgen · started 2025-07-16
📍 Cambridge · Edinburgh · Leicester · Newcastle upon Tyne
NCT06570798 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Heart Failure, Left Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC · started 2023-05-31
📍 London · Newcastle upon Tyne
NCT05714085 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC · started 2021-05-12
📍 Cambridge · Glasgow · London · Newcastle upon Tyne · Sheffield
NCT07218029 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Relapsed or Refractory Multiple Myeloma
Celgene · started 2022-09-20
📍 Cambridge · Truro · Airdrie · London · Leicester
NCT05519085 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
UCB Biopharma SRL · started 2024-11-21
📍 Bath · Belfast · Leeds · London · Newcastle upon Tyne
NCT06617325 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma
BeOne Medicines · started 2021-09-13
📍 Edinburgh · Leeds · Newcastle upon Tyne · Newmarket · Norwich
NCT05006716 on ClinicalTrials.gov ↗
No trials match your search.

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Cite this page

Priya Life Science (2026). Clinical Trials in the UK Tracker. Available at: https://priyalifescience.com/clinical-trials-uk/city/newcastle-upon-tyne (Accessed: 26 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one UK site, most recently updated first, refreshed daily. This is a curated slice of the registry, not every UK trial; UK studies may also be registered on ISRCTN. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our UK Pharma Salary Guide, or see our Ireland, EU and USA trackers.