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Trackers› Clinical trials› New Jersey
Clinical trial register · United States · industry-sponsored

Clinical Trials in New Jersey, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9118 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 06 Oct 2026, 03:16 UTC
9118
Studies in scope
industry-sponsored, all four open statuses
4945
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 5290 Florida 4430 Illinois 2481 Georgia 2368 Arizona 2238
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Merck Sharp & Dohme LLC34 AstraZeneca31 Novartis Pharmaceuticals24 Bristol-Myers Squibb22 Pfizer21
State
California5290 Florida4430 Illinois2481 Georgia2368 Arizona2238
All 51 states
Target enrolment
to

Trials with a site in New Jersey

782 of 9118 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
A Registry to Gather Real World Use Data on the Cerene® Cryotherapy Device
NCT05922657Heavy Menstrual Bleeding, Abnormal Uterine Bleeding, Menorrhagia
Channel Medsystems
Observational
300
New Jersey, Ohio
2023-06-09
Active, closed
A Study of BMS-986449 With and Without Nivolumab in Participants With Advanced Solid Tumors
NCT05888831Advanced Solid Tumors
DrugsOpdivo·Nivolumab
Bristol-Myers Squibb
Phase 1/2
100
California, Connecticut, New Jersey, New York
2023-06-06
Active, closed
A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL)
NCT05879744NHL, NHL, Relapsed, Adult
DrugCLN-978
Cullinan Therapeutics Inc.
Phase 1
90
Alabama, California, Georgia, Massachusetts, New Jersey, Texas
2023-05-31
Active, closed
An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis
NCT05809531C3G, IC-MPGN, C3 Glomerulopathy, C3 Glomerulonephritis
DrugPegcetacoplan
Apellis Pharmaceuticals, Inc.
Phase 3
100
California, Colorado, Florida, Georgia, Iowa, Michigan, New Jersey, New York
2023-05-29
Recruiting
XTX301 in Patients With Advanced Solid Tumors
NCT05684965Advanced Solid Tumor
Xilio Development, Inc.
Phase 1/2
358
California, Connecticut, Minnesota, Missouri, New Jersey, Ohio, Pennsylvania, Texas
2023-05-11
Recruiting
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
NCT05716100Focal Onset Seizures
DrugAzetukalner
Xenon Pharmaceuticals Inc.
Phase 3
360
Arkansas, California, Florida, Idaho, Illinois, Maryland, Michigan, New Jersey
2023-05-09
By invitation
G7 Freedom Constrained Vivacit-E Liners
NCT05587244Osteoarthritis, Hip, Rheumatoid Arthritis, Non-Union Fracture, Trochanteric Fractures
Zimmer Biomet
Not applicable
202
Alabama, California, Florida, New Jersey, Ohio, Tennessee, Texas, Utah
2023-05-08
Recruiting
Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease
NCT05295615Alzheimer Disease
Herrick Medical LLC
Not applicable
40
New Jersey
2023-05-01
Recruiting
Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries
NCT05496296Pressure Ulcers Stage II, Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
ULURU Inc.
Not applicable
300
California, District of Columbia, Illinois, Maryland, New Jersey, New York, Pennsylvania, Texas
2023-04-30
Active, closed
Clinical Study of a Micro-Implantable Pulse Generator for the Treatment of Peripheral Neuropathic Pain (COMFORT 2)
NCT05870124Peripheral Neuralgia, Peripheral Neuropathy, Chronic Pain
Nalu Medical, Inc.
Not applicable
185
Arizona, California, Colorado, District of Columbia, Florida, Kansas, Michigan, New Jersey
2023-04-27
Active, closed
Survival and Dialysis Independency in Highly Sensitized Patients After Desensitization With Imlifidase and Tx of Kidneys
NCT05714514Kidney Transplantation in Highly Sensitized Patients
DrugImlifidase
Hansa Biopharma AB
Observational
64
Alabama, California, Illinois, Maryland, Massachusetts, Missouri, New Jersey, New York
2023-04-21
Recruiting
A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas
NCT05685173B-cell Non-Hodgkins Lymphoma (B-NHL)
DrugOdronextamab
Regeneron Pharmaceuticals
Phase 1
107
California, Kentucky, Massachusetts, New Jersey, New York, Texas
2023-04-20
Active, closed
Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma
NCT05539430Gastric Cancer, Gastroesophageal-junction Cancer, Esophageal Cancer, Pancreatic Cancer
Legend Biotech USA Inc
Phase 1
56
Florida, Michigan, New Jersey, New York, North Carolina, Oregon, Tennessee, Washington
2023-04-18
Active, closed
An Adjunct Study to Assess Guided ADHD Therapy for Managing the Extent and Severity of Symptoms
NCT05805176ADHD
Lumos Labs, Inc.
Not applicable
194
Florida, Michigan, Missouri, New Jersey
2023-04-15
Recruiting
Study of SGR-1505 in Mature B-Cell Neoplasms
NCT05544019Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL, Waldenstrom Macroglobulinemia
Schrödinger, Inc.
Phase 1
98
Arizona, Delaware, Florida, Massachusetts, New Jersey, New York, North Carolina, Ohio
2023-04-10
Active, closed
A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma
NCT05692180Asthma
DrugBenralizumab
AstraZeneca
Phase 3
94
California, Florida, Kentucky, Louisiana, Missouri, New Jersey, New York, Ohio
2023-04-05
Recruiting
A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS)
NCT05795465Respiratory Distress Syndrome, Acute
GEn1E Lifesciences
Phase 2
52
District of Columbia, Kansas, Maryland, Mississippi, Missouri, New Jersey, New York, Ohio
2023-04-04
Active, closed
A Study of NanO2™ Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM
NCT03862430Glioblastoma Multiforme
NuvOx LLC
Phase 2
87
Arizona, California, Connecticut, Illinois, Louisiana, Missouri, New Jersey, North Carolina
2023-03-31
Active, closed
PerQseal® Clinical Study
NCT05653336Percutaneous Large Hole Vascular Closure
Vivasure Medical Limited
Not applicable
149
Arizona, California, Maine, New Jersey, New York, Ohio, Pennsylvania, Texas
2023-03-30
Active, closed
A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome
NCT05627557Childhood Idiopathic Nephrotic Syndrome
DrugsAcetaminophen/paracetamol·Diphenhydramine hydrochloride·Methylprednisolone·Obinutuzumab
Hoffmann-La Roche
Phase 3
85
California, Florida, Georgia, New Jersey, North Carolina, Utah, Virginia
2023-03-29
Active, closed
A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma
NCT04485949Glioblastoma
Imvax
Phase 2
99
Florida, Massachusetts, Michigan, New Hampshire, New Jersey, New York, North Carolina, Ohio
2023-03-20
By invitation
G7 Dual Mobility With Vivacit-E or Longevity PMCF
NCT05548972Hip Osteoarthritis, Rheumatoid Arthritis, Joint Diseases, Avascular Necrosis
Zimmer Biomet
Not applicable
358
Arkansas, Colorado, New Jersey, New York, Ohio, Oregon
2023-03-20
Active, closed
A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)
NCT05766501HIV Infection
DrugDOR/ISL
Merck Sharp & Dohme LLC
Phase 3
641
Alabama, Arizona, California, District of Columbia, Florida, Georgia, Missouri, New Jersey
2023-03-17
Recruiting
Vivistim Registry for Paired VNS Therapy (GRASP)
NCT05301140Upper Extremity Problem
MicroTransponder Inc.
Observational
1,000
Florida, Illinois, Kansas, Kentucky, New Jersey, New York, Pennsylvania, Texas
2023-03-15
Active, closed
The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study
NCT05489588Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates
Not applicable
165
California, Connecticut, District of Columbia, Florida, Illinois, Massachusetts, Michigan, New Jersey
2023-03-02
Active, closed
A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
NCT05738486Alzheimer's Disease, Dementia, Brain Diseases, Central Nervous System Diseases
DrugsDonanemab·Dexamethasone
Eli Lilly and Company
Phase 3
1,175
Arizona, California, Florida, Georgia, Massachusetts, Michigan, New Jersey, Rhode Island
2023-02-28
Active, closed
Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors
NCT05651022Solid Tumor, Adult, HCC - Hepatocellular Carcinoma, CRC (Colorectal Cancer), Pancreatic Adenocarcinoma
DrugTislelizumab
Indaptus Therapeutics, Inc
Phase 1/2
120
California, Georgia, Michigan, Missouri, New Jersey, New York, Ohio, Pennsylvania
2023-02-28
Active, closed
A Prospective Cohort Post Market Registry Evaluating Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)
NCT05398341Anterior Cruciate Ligament Injuries
Miach Orthopaedics
Observational
300
California, Colorado, Florida, New Jersey, New York, North Carolina, Oregon
2023-02-28
Recruiting
A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
NCT05471856Solid Tumors
DrugEzabenlimab
Boehringer Ingelheim
Phase 1
66
California, Connecticut, New Jersey
2023-02-24
Active, closed
Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy
NCT06018558Geographic Atrophy
Ocugen
Phase 1/2
60
Arizona, Florida, Indiana, Mississippi, Missouri, New Jersey, North Carolina, Pennsylvania
2023-02-23
Recruiting
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
NCT05651932Multiple Myeloma, Myeloma, Myeloma Multiple
DrugsMezigdomide·Carfilzomib·Pomalidomide·Dexamethasone
K36 Therapeutics, Inc.
Phase 1
165
California, Florida, Georgia, Massachusetts, Minnesota, New Jersey, New York, North Carolina
2023-02-22
Active, closed
A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Antiretroviral Therapy (ART) (MK-8591A-051)
NCT05631093HIV-1 Infection
DrugsDOR/ISL·B/F/TAF
Merck Sharp & Dohme LLC
Phase 3
553
California, District of Columbia, Florida, Georgia, New Jersey, Pennsylvania, Texas
2023-02-20
Recruiting
CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
NCT05722418Relapsed/Refractory Multiple Myeloma
DrugsFludarabine·Cyclophosphamide
Caribou Biosciences, Inc.
Phase 1
50
Alabama, Colorado, Florida, Kentucky, New Jersey, New York, North Carolina, Ohio
2023-02-06
Active, closed
A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia
NCT05662319Hemophilia
DrugsAntithrombin·Clotting factor concentrates·Fitusiran
Sanofi
Phase 3
91
California, Minnesota, New Jersey, New York, Ohio, Pennsylvania, Texas
2023-02-01
Active, closed
Stryker PEEK Customized Implant: A Prospective Post Market Follow Up to Evaluate Safety, Performance and Effectiveness
NCT05362370Cranioplasty, Craniofacial Abnormalities, Craniofacial Injuries
Stryker Craniomaxillofacial
Observational
99
Kentucky, New Jersey, New York, Pennsylvania, South Carolina
2023-02-01
Active, closed
A Feasibility Trial to Investigate the Safety and Between-group Effect Size of STIMULAN VG and Standard of Care (SoC) in Participants With Diabetic Foot Osteomyelitis
NCT05539963Diabetic Foot Osteomyelitis
Biocomposites Ltd
Phase 2
61
Arizona, Arkansas, Nevada, New Jersey, New York, North Carolina
2023-01-23
Active, closed
A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery
NCT05608291Melanoma
DrugsFianlimab·Cemiplimab·Keytruda·Pembrolizumab
Regeneron Pharmaceuticals
Phase 3
1,564
California, Colorado, Florida, Illinois, Massachusetts, Michigan, New Jersey, New York
2023-01-16
Active, closed
A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))
NCT05731128Colitis Ulcerative
DrugDupilumab
Sanofi
Phase 2
68
California, Florida, Georgia, New Jersey, New York, North Carolina, Pennsylvania, Texas
2023-01-12
Active, closed
A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors
NCT05653882Solid Tumor, Non Small Cell Lung Cancer, Melanoma, Squamous Cell Carcinoma of Head and Neck
DrugsEtakafusp alfa·Keytruda·Pembrolizumab
Asher Biotherapeutics, Inc.
Phase 1
552
California, Connecticut, Florida, Illinois, Massachusetts, Michigan, Missouri, New Jersey
2023-01-04
Recruiting
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
NCT05313165Critical Limb Ischemia, Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease
LimFlow, Inc.
Not applicable
100
California, Connecticut, Florida, Illinois, Massachusetts, Missouri, New Hampshire, New Jersey
2022-12-22
Recruiting
PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study
NCT05681689Helicobacter Pylori Infection, Post-Treatment, Efficacy
ARJ Medical, Inc.
Phase 3
77
Florida, New Jersey
2022-12-21
Active, closed
ForeseeHome NRich Registry
NCT05690880Age-Related Macular Degeneration
Notal Vision Inc.
Observational
20,000
New Jersey
2022-12-15
Active, closed
A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma
NCT05675449Multiple Myeloma
DrugsElranatamab·Carfilzomib
Pfizer
Phase 1
59
Arkansas, California, Florida, Georgia, Iowa, Maryland, Massachusetts, New Jersey
2022-12-14
Active, closed
Clinical Investigation of the da Vinci Surgical System
NCT05682742Thymoma, Mediastinal Tumor, Gynecologic Disease, Gynecologic Cancer
Intuitive Surgical
Not applicable
53
Florida, Michigan, New Jersey, Ohio
2022-12-12
Active, closed
A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma
NCT05529316Advanced Melanoma
DrugsBalstilimab·Botensilimab
Agenus Inc.
Phase 2
150
Arizona, California, Connecticut, District of Columbia, Massachusetts, New Jersey
2022-12-12
Active, closed
A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer
NCT05608044Metastatic Colorectal Cancer
DrugsBalstilimab·Botensilimab
Agenus Inc.
Phase 2
234
Arizona, California, Colorado, Delaware, Florida, Massachusetts, Michigan, New Jersey
2022-11-30
Active, closed
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
NCT05538130Melanoma, Glioma, Thyroid Cancer, Non-Small Cell Lung Cancer
DrugPF-07799933
Pfizer
Phase 1
148
Alabama, Arkansas, California, Florida, Louisiana, Massachusetts, Michigan, New Jersey
2022-11-30
Recruiting
A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors
NCT05584670Solid Tumor
DrugsSAR445877·ADG126·Zirabev·Erbitux
Sanofi
Phase 1/2
542
Delaware, Iowa, Kansas, Michigan, New Jersey, New York, Rhode Island, Texas
2022-11-29
Active, closed
Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis
NCT05588843Colitis Ulcerative
Sanofi
Phase 2
187
California, Georgia, Illinois, Missouri, Nevada, New Jersey, New York, Tennessee
2022-11-25
Active, closed
A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC
NCT05611671Inflammatory Bowel Diseases, Colitis, Ulcerative
DrugZotemtegrast
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
Phase 2
280
Arizona, California, Florida, New Jersey, Ohio, Texas
2022-11-21
Active, closed
Dazucorilant in Patients With Amyotrophic Lateral Sclerosis
NCT05407324Amyotrophic Lateral Sclerosis
Corcept Therapeutics
Phase 2
279
Arizona, California, New Jersey, New York
2022-11-15
Active, closed
Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
NCT05546580Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
DrugsXospata·Gilteritinib
Oryzon Genomics S.A.
Phase 1
50
Arizona, Florida, Maryland, Massachusetts, New Jersey, New York, North Carolina, Oregon
2022-11-14
Recruiting
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
NCT05498428Carcinoma, Non-small-Cell Lung
DrugsDirect Anticoagulant·LMWH·DOAC·Low molecular weight heparin
Janssen Research & Development, LLC
Phase 2
520
California, District of Columbia, Florida, Kansas, Maryland, Massachusetts, Missouri, New Jersey
2022-11-11
Recruiting
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
NCT05623020Multiple Myeloma
DrugsElranatamab·Bortezomib·Daratumumab·Lenalidomide
Pfizer
Phase 3
1,060
Florida, Nebraska, Nevada, New Jersey, New York, Texas, Utah
2022-11-10
Recruiting
Study Evaluating UCART20x22 in B-Cell Non-Hodgkin Lymphoma
NCT05607420B-cell Non-Hodgkin Lymphoma (B-NHL)
DrugAlemtuzumab
Cellectis S.A.
Phase 1/2
80
Illinois, Massachusetts, New Jersey, Texas
2022-11-01
Active, closed
Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type
NCT05397639Agitation, Alzheimer's Type Dementia
Suven Life Sciences Limited
Phase 3
375
California, Connecticut, Florida, Illinois, New Jersey, New York, Ohio, South Carolina
2022-11-01
Recruiting
Avalglucosidase Alfa Pregnancy Study
NCT05734521Pompe Disease, Pregnancy
DrugAvalglucosidase alfa
Sanofi
Observational
100
New Jersey
2022-10-26
Active, closed
A Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV
NCT05481151Polycythemia Vera
DrugBesremi
PharmaEssentia
Phase 3
111
Florida, Indiana, Kansas, Kentucky, Louisiana, Maryland, Missouri, New Jersey
2022-10-26
Active, closed
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused Etentamig (ABBV-383) in Combination With Anti-Cancer Regimens for the Treatment of Adult Participants With Relapsed/Refractory Multiple Myeloma
NCT05259839Relapsed/Refractory Multiple Myeloma
DrugsEtentamig·Pomalidomide·Daratumumab·Lenalidomide
AbbVie
Phase 1
283
Arkansas, Florida, Maryland, Massachusetts, Michigan, New Jersey, New York, North Carolina
2022-10-20
Active, closed
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
NCT05581004Locally Advanced or Metastatic Solid Tumors, NSCLC, HNSCC, Melanoma
DrugsTecentriq·Atezolizumab·Keytruda·Pembrolizumab
Genentech, Inc.
Phase 1
165
California, Colorado, Florida, Georgia, Massachusetts, Missouri, New Jersey, Tennessee
2022-10-20
Recruiting
A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma
NCT05372354Multiple Myeloma
DrugsBMS-986158·Tazemetostat·Mezigdomide·Trametinib
Bristol-Myers Squibb
Phase 1/2
260
Alabama, Maryland, Massachusetts, New Jersey, New York
2022-10-18
Active, closed
A Retrospective Assessment of OviTex PRS (OviTex)
NCT05736848Reconstructive Surgical Procedures
Tela Bio Inc
Observational
200
Florida, Georgia, Massachusetts, Michigan, New Jersey, New York, South Carolina, Texas
2022-09-27
Active, closed
Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Cutaneous Squamous Cell Carcinoma
NCT05323253Recurrent Squamous Cell Carcinoma
Alpha Tau Medical LTD.
Not applicable
86
Arizona, California, Florida, Georgia, Minnesota, New Jersey, New Mexico, New York
2022-09-21
Recruiting
Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes
NCT04011020Type 1 Diabetes
Throne Biotechnologies Inc.
Phase 3
80
New Jersey
2022-09-20
Active, closed
Clinical Application of Stem Cell Educator Therapy in Alopecia Areata
NCT04011748Alopecia Areata, Alopecia Totalis, Alopecia Universalis
Throne Biotechnologies Inc.
Phase 2
20
New Jersey
2022-09-20
Active, closed
Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOT™_CA)
NCT05574361Liver Transplantation
Organ Recovery Systems, Inc.
Not applicable
385
Illinois, New Jersey, Ohio, Utah
2022-09-19
Active, closed
Phase 2a to Evaluate PL-8177 in Subjects with Active Ulcerative Colitis (UC)
NCT05466890Ulcerative Colitis, Ulcerative Colitis Acute, Ulcerative, Ulcerative Colitis Flare
Palatin Technologies, Inc
Phase 2
16
Arizona, California, Florida, Kansas, Louisiana, New Jersey, New York, Pennsylvania
2022-09-15
Recruiting
Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)
NCT05308264Low Risk Myelodysplastic Syndromes
Rigel Pharmaceuticals
Phase 1/2
86
California, Florida, Missouri, New Jersey, New York, North Carolina, Ohio, Texas
2022-09-12
Recruiting
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
NCT05489211Endometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer, Ovarian Cancer
DrugsPrednisone/Prednisolone·Volrustomig·Rilvegostomig·Dato-DXd
AstraZeneca
Phase 2
454
California, Indiana, Kansas, Massachusetts, Michigan, New Jersey, New Mexico, New York
2022-09-06
Active, closed
Study of Sonrotoclax (BGB-11417) Monotherapy in Participants With Relapsed or Refractory Mantle Cell Lymphoma
NCT05471843Mantle Cell Lymphoma, Refractory Mantle Cell Lymphoma (MCL), Relapsed Mantle Cell Lymphoma
DrugSonrotoclax
BeOne Medicines
Phase 1/2
125
Alabama, Indiana, Louisiana, Maryland, New Jersey, Texas
2022-09-05
Recruiting
TVMR With the INNOVALVE System Trial - Early Feasibility Study
NCT04919980Mitral Valve Regurgitation (Degenerative or Functional)
Edwards Lifesciences
Not applicable
85
California, Florida, Georgia, Illinois, Michigan, Minnesota, Missouri, New Jersey
2022-09-01
Active, closed
Safety, Tolerability and PK of Subcutaneous D-4517.2 in Subjects With Wet AMD or DME
NCT05387837Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
DrugAflibercept
Ashvattha Therapeutics, Inc.
Phase 2
50
California, Illinois, Indiana, Maryland, Massachusetts, Missouri, New Jersey, Pennsylvania
2022-08-31
Recruiting
Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
NCT05394103Advanced Cancer, Metastatic Cancer
DrugsKeytruda·Pembrolizumab
Qurient Co., Ltd.
Phase 1/2
130
Arizona, California, Florida, Illinois, Minnesota, New Jersey, Texas
2022-08-30
Recruiting
A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery
NCT05156983Coagulation Disorder
Takeda
Phase 3
440
Arkansas, California, Colorado, Florida, New Jersey, North Carolina, Ohio, Oklahoma
2022-08-24
Active, closed
First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC)
NCT05361395Extensive Stage Small Cell Lung Cancer
DrugsTarlatamab·Tecentriq·Etoposide·Atezolizumab
Amgen
Phase 1
184
California, Delaware, Michigan, New Jersey, New York, North Carolina, South Dakota, Washington
2022-08-24
Active, closed
A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)
NCT04752813Glioblastoma, Glioblastoma Multiforme
DrugTemozolomide
BPGbio
Phase 2
50
California, Massachusetts, New Jersey, New York, Texas, Virginia
2022-08-22
Active, closed
Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes
NCT05506423Open Angle Glaucoma
Iantrek, Inc.
Observational
300
California, Florida, Georgia, Maryland, Nevada, New Jersey, New York, Pennsylvania
2022-08-17
Active, closed
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen
NCT05502341HIV-1-infection
DrugsBictegravir·Lenacapavir
Gilead Sciences
Phase 2/3
689
California, Colorado, Connecticut, Florida, Georgia, Illinois, Missouri, New Jersey
2022-08-16
Active, closed
A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma
NCT05421663Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse
Janssen Research & Development, LLC
Phase 1/2
166
California, Colorado, Iowa, Kentucky, New Jersey, North Carolina, Ohio, Pennsylvania
2022-08-12
Active, closed
A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer
NCT05388669Advanced or Metastatic Non-small Cell Lung Cancer
DrugsLazertinib·Amivantamab
Janssen Research & Development, LLC
Phase 3
418
California, Colorado, Florida, Kansas, Michigan, New Jersey, New York, Oregon
2022-08-05
Active, closed
Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment
NCT05261399Carcinoma, Non-Small-Cell Lung
DrugsSavolitinib·Tagrisso·Osimertinib·Pemetrexed
AstraZeneca
Phase 3
341
Florida, Hawaii, New Jersey, New York, Tennessee
2022-08-03
Active, closed
A Phase 1/2 Study of BA3071 in Patients With Solid Tumors
NCT05180799NSCLC, Melanoma
DrugsPemetrexed·Nivolumab·Pembrolizumab
BioAtla, Inc.
Phase 1/2
320
California, Georgia, Indiana, New Jersey, New York, Ohio, Oregon, Utah
2022-08-03
Active, closed
A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II)
NCT05371613Mucopolysaccharidosis II
DrugsIdursulfase·Tividenofusp alfa
Denali Therapeutics Inc.
Phase 2/3
65
California, Illinois, New Jersey, North Carolina, Ohio, Pennsylvania, Texas, Utah
2022-07-21
Active, closed
Safety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL Patients
NCT05222555Diffuse Large B Cell Lymphoma
DrugsTafasitamab·Lenalidomide
Incyte Corporation
Phase 1/2
53
New Jersey, Texas, Washington
2022-07-19
Recruiting
Safety and Effectiveness of the HIT Reverse HRS
NCT05357378Degenerative Joint Disease, Osteoarthritis, Hip, Avascular Necrosis of Hip, Traumatic Arthropathy-Hip
Hip Innovation Technology
Not applicable
288
Florida, Maryland, New Jersey, Ohio
2022-07-15
Recruiting
Tempus Small Cell Lung Cancer Observational Study (Sculptor)
NCT05257551Small Cell Lung Cancer
Tempus AI
Observational
200
California, Colorado, Illinois, Maryland, New Jersey, North Carolina, Ohio, Oklahoma
2022-07-13
Active, closed
A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab
NCT05142696Extensive Stage Small Cell Lung Cancer
Drugs[177Lu]Lu-DOTA-TATE·[68Ga]Ga-DOTA-TATE·Lutathera·Atezolizumab
Novartis Pharmaceuticals
Phase 1/2
55
Florida, Georgia, Kentucky, Missouri, New Jersey, Ohio, Pennsylvania
2022-07-13
Recruiting
The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
NCT05203172Solid Tumors
DrugsVemurafenib·Binimetinib·Encorafenib·Zirabev
Pfizer
Phase 4
210
Arizona, Georgia, Massachusetts, Minnesota, Missouri, New Jersey, New York, North Carolina
2022-07-05
Active, closed
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
NCT05355701Melanoma, Non-Small-Cell Lung Cancer, Thyroid Cancer, Glioma
DrugsPF-07799933·Binimetinib·Erbitux·Midazolam
Pfizer
Phase 1
103
Arkansas, Colorado, Florida, Massachusetts, Michigan, New Jersey, New York, Ohio
2022-07-05
Active, closed
SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM
NCT05405166Plasma Cell Myeloma Recurrent
DrugsParacetamol / Acetaminophen·Montelukast·Diphenhydramine·Isatuximab
Sanofi
Phase 3
531
Colorado, Florida, Mississippi, New Jersey, New York, North Carolina, Ohio, South Carolina
2022-06-23
Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
NCT05438732Age-Related Macular Degeneration, Geographic Atrophy
VisionCare, Inc.
Not applicable
125
California, Florida, Massachusetts, Michigan, Nebraska, New Jersey, North Carolina, Ohio
2022-06-16
Recruiting
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
NCT05245500Mesothelioma, Non Small Cell Lung Cancer, Malignant Peripheral Nerve Sheath Tumors, Solid Tumor
DrugNavlimetostat
Bristol-Myers Squibb
Phase 1
336
Arizona, Colorado, Florida, Illinois, Massachusetts, Michigan, Minnesota, New Jersey
2022-06-09
Recruiting
Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants
NCT05285735Pregnancy, Malaria
Amivas Inc.
Observational
25
New Jersey
2022-06-08
Active, closed
THIO Sequenced With Cemiplimab in Advanced NSCLC
NCT05208944Carcinoma, Non-Small-Cell Lung
DrugsThiotepa·Cemiplimab
Maia Biotechnology
Phase 2
227
Alabama, New Jersey
2022-06-08
Recruiting
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
NCT05365581Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma
DrugsASP2138·Ramucirumab·Fluorouracil·Leucovorin
Astellas Pharma Global Development, Inc.
Phase 1
398
California, Illinois, Kansas, New Jersey, New York, North Carolina, Texas, Washington
2022-06-07
Active, closed
A Study in People With Advanced Cancer to Test How Well Different Doses of BI 770371 Alone or in Combination With Ezabenlimab Are Tolerated
NCT05327946Solid Tumors
DrugsBI 770371·Ezabenlimab
Boehringer Ingelheim
Phase 1
42
Florida, New Jersey
2022-05-17
Recruiting
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
NCT05039619Lupus Nephritis
DrugsAcetaminophen/paracetamol·Diphenhydramine hydrochloride·Mycophenolate Mofetil·Methylprednisolone
Hoffmann-La Roche
Phase 2
40
California, Colorado, Georgia, Indiana, Louisiana, New Jersey, New York, Ohio
2022-05-12
Active, closed
Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study
NCT05291884Heart Failure, Acute Decompensated Heart Failure
Abiomed Inc.
Not applicable
10
Georgia, Illinois, Massachusetts, New Jersey, Ohio
2022-04-20
Active, closed
CONVERGE Post-Approval Study (PAS)
NCT05393180Chronic Atrial Fibrillation
AtriCure, Inc.
Not applicable
53
California, Connecticut, Florida, Georgia, Kentucky, Maryland, Massachusetts, New Jersey
2022-04-13
By invitation
Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With and Without Diabetic Retinopathy
NCT05296447Diabetic Retinopathy, DR
DrugsEylea·Aflibercept
AbbVie
Phase 2
100
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Jersey
2022-04-04
Recruiting
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
NCT04895436Chronic Lymphocytic Leukemia (CLL)
DrugsVenclexta·Obinutuzumab·Venetoclax
AbbVie
Phase 2
75
California, Georgia, Iowa, Massachusetts, Michigan, Minnesota, Mississippi, New Jersey
2022-03-28
Active, closed
Study of Capivasertib + Docetaxel vs Placebo + Docetaxel as Treatment for Metastatic Castration Resistant Prostate Cancer (mCRPC)
NCT05348577Prostate Cancer
DrugsCapivasertib·Docetaxel
AstraZeneca
Phase 3
1,035
Arizona, California, Colorado, Maryland, Minnesota, New Jersey, New York, Ohio
2022-03-25
Active, closed
A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma
NCT04980222Lymphoma
DrugsGlofitamab·Tocilizumab·Vincristine·Doxorubicin
Hoffmann-La Roche
Phase 2
46
California, Iowa, Michigan, Missouri, New Jersey, New York, Texas
2022-03-22
Active, closed
Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
NCT05280470Extensive-stage Small-cell Lung Cancer
DrugIfinatamab Deruxtecan
Daiichi Sankyo
Phase 2
187
Arkansas, Florida, Illinois, Maryland, Massachusetts, Michigan, Missouri, New Jersey
2022-03-09
Recruiting
CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study
NCT04883411Neck Pain, Spondylosis, Spondylosis With Myelopathy, Spondylosis With Radiculopathy
ReVivo Medical, Corp.
Not applicable
50
New Jersey, New York, Ohio
2022-03-07
Active, closed
Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations
NCT05215340Metastatic Non Small Cell Lung Cancer
DrugsDato-DXd·Keytruda·Pembrolizumab
Daiichi Sankyo
Phase 3
740
Arizona, California, Colorado, Maryland, Massachusetts, New Hampshire, New Jersey, New York
2022-03-04
Active, closed
A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer
NCT05243550Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
UroGen Pharma Ltd.
Phase 3
240
Arizona, California, Kansas, Maryland, Missouri, New Jersey, New York, Tennessee
2022-03-01
Recruiting
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
NCT04988555Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute, Multiple Myeloma, Myelodysplastic Syndromes
DrugsAzoles·Gilteritinib·Azacitidine·Venetoclax
Sumitomo Pharma America, Inc.
Phase 1/2
606
California, Colorado, District of Columbia, Florida, Illinois, Maryland, Massachusetts, New Jersey
2022-02-28
Active, closed
A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection
NCT05120349Non-Small Cell Lung Cancer
DrugsTagrisso·Osimertinib
AstraZeneca
Phase 3
390
Alaska, California, Colorado, Delaware, Georgia, Illinois, Maryland, New Jersey
2022-02-21
Active, closed
A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration
NCT05230537Age-Related Macular Degeneration
DrugIptacopan
Novartis Pharmaceuticals
Phase 2
168
California, Colorado, Florida, Indiana, Louisiana, Maryland, Massachusetts, New Jersey
2022-02-17
Active, closed
Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis
NCT05138133Lupus Nephritis
DrugAnifrolumab
AstraZeneca
Phase 3
363
Arizona, California, Florida, Georgia, Kentucky, New Jersey, New York, North Carolina
2022-02-15
Active, closed
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters
NCT05383274Urethral Stricture
Urotronic Inc.
Phase 4
34
Arkansas, Florida, Louisiana, Maryland, Nevada, New Jersey, New York, Texas
2022-02-14
Recruiting
Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors
NCT05269316Solid Tumor, Advanced Solid Tumor
Impact Therapeutics, Inc.
Phase 1/2
61
New Jersey, New York, South Carolina, Texas
2022-02-11
Active, closed
A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)
NCT05094336Advanced MTAP-null Solid Tumors
DrugsAnvumetostat·Docetaxel
Amgen
Phase 1/2
329
California, Florida, Indiana, Maryland, Michigan, Missouri, New Jersey, New York
2022-02-01
Active, closed
A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
NCT05081609Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor, Platinum-resistant Ovarian Cancer
DrugsAdo-trastuzumab emtansine·Trastuzumab emtansine·Trastuzumab·Pembrolizumab
Ascendis Pharma Oncology Division A/S
Phase 1/2
320
California, Illinois, Kentucky, Massachusetts, New Jersey, New York, North Carolina, Ohio
2022-01-11
Active, closed
Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures
NCT05067634Partial Epilepsy
SK Life Science, Inc.
Phase 3
140
Arizona, California, Connecticut, Georgia, Maryland, Minnesota, New Jersey, New York
2022-01-10
Active, closed
Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer
NCT04905069Prostate Cancer
Boston Scientific Corporation
Not applicable
500
Florida, Kansas, Michigan, New Jersey, Pennsylvania, South Carolina
2021-12-21
Recruiting
A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)
NCT05067283Advanced Solid Tumors
DrugsCalderasib·Leucovorin·Cetuximab·Adrucil
Merck Sharp & Dohme LLC
Phase 1
830
Florida, Michigan, New Jersey, New York, Virginia, Wisconsin
2021-12-17
Active, closed
Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma
NCT05079282Relapsed or Refractory T Cell Lymphoma
DrugONO-4685
Ono Pharmaceutical Co., Ltd.
Phase 1
217
Alabama, California, Connecticut, Georgia, Massachusetts, Michigan, Missouri, New Jersey
2021-12-10
Recruiting
Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System
NCT04890821Tricuspid Regurgitation Functional
Cardiac Implants LLC
Not applicable
15
New Jersey, New York
2021-12
Recruiting
A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer
NCT05125016Metastatic Castration-resistant Prostate Cancer
DrugsNezastomig·REGN4336
Regeneron Pharmaceuticals
Phase 1/2
228
California, Connecticut, Kentucky, Maryland, New Jersey, New York, North Carolina, Ohio
2021-11-30
Active, closed
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
NCT04958265Atypical Hemolytic Uremic Syndrome
DrugCrovalimab
Hoffmann-La Roche
Phase 3
41
Colorado, Nebraska, New Jersey
2021-11-17
Recruiting
Ceribell Delirium Data Collection Study
NCT04962815Delirium
Ceribell Inc.
Observational
200
California, Florida, Iowa, Missouri, New Jersey, North Carolina, Pennsylvania
2021-11-10
Active, closed
Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.
NCT05256771Fat Reduction, Muscle Tone Increased
Venus Concept
Not applicable
36
California, New Jersey, Tennessee
2021-11-01
Active, closed
A Study of CLN-619 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors
NCT05117476Advanced Solid Tumor, NSCLC
DrugsCLN-619·Carboplatin (AUC 6)·Dato-DXd·Pemetrexed
Cullinan Therapeutics Inc.
Phase 1
440
Alabama, California, Florida, Massachusetts, Michigan, New Jersey, New York, North Carolina
2021-10-29
Recruiting
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT
NCT04862468Thrombosis, Deep Vein, Iliofemoral; Thrombosis
Mercator MedSystems, Inc.
Phase 2
80
Arizona, California, Connecticut, Florida, Georgia, Louisiana, Maryland, New Jersey
2021-10-29
Active, closed
A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations
NCT05048797Locally Advanced or Metastatic Non-Small Cell Lung Cancer
DrugsTrastuzumab deruxtecan·Pemetrexed·Cisplatin·Carboplatin
AstraZeneca
Phase 3
454
Alaska, California, Maryland, Massachusetts, Michigan, New Jersey, New York, Pennsylvania
2021-10-28
Recruiting
A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments
NCT05020236Multiple Myeloma
DrugsDarzalex·Elranatamab·Pomalidomide·Daratumumab
Pfizer
Phase 3
893
California, Colorado, Florida, Louisiana, New Jersey, New York
2021-10-04
Active, closed
Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing
NCT05059522Advanced Malignancies, NSCLC, Ovarian Cancer, Urothelial Cancer
DrugsCMP 001·Utomilumab·Talazoparib·Axitinib
Pfizer
Phase 3
77
Arkansas, California, Florida, New Jersey, New York, Pennsylvania, Texas, Washington
2021-09-29
Recruiting
First in Human, Dose Escalation Study of AN4005
NCT04999384Advanced Solid Tumor, Advanced Lymphoma
Adlai Nortye Biopharma Co., Ltd.
Phase 1
31
New Jersey, New York, South Carolina, Virginia
2021-09-27
Active, closed
A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
NCT05023980Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugsRiabni·Ruxience·Truxima·Pirtobrutinib
Loxo Oncology, Inc.
Phase 3
282
California, Florida, New Jersey, New York
2021-09-23
Recruiting
Innovations in Genicular Outcomes Registry
NCT05495334Knee Osteoarthritis
Pacira Pharmaceuticals, Inc
Observational
10,000
Arizona, California, Florida, Louisiana, Maryland, Massachusetts, Nebraska, New Jersey
2021-09-23
Active, closed
A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
NCT05050097Multiple Myeloma
DrugsTalquetamab·Carfilzomib·Pomalidomide·Daratumumab
Janssen Research & Development, LLC
Phase 1
166
Alabama, California, Colorado, Georgia, Indiana, New Jersey, New York, North Carolina
2021-09-22
Recruiting
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
NCT04973605Relapsed/Refractory Multiple Myeloma
DrugsSonrotoclax·Carfilzomib·Pomalidomide·Daratumumab
BeOne Medicines
Phase 1/2
246
Alabama, California, Florida, Georgia, Illinois, Massachusetts, Missouri, New Jersey
2021-09-16
Active, closed
Open-label, Follow-up of Doravirine/Islatravir (DOR/ISL 100 mg/0.75mg) for Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection (MK-8591A-033)
NCT04776252HIV-1 Infection
DrugDOR/ISL
Merck Sharp & Dohme LLC
Phase 3
2,000
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Missouri, New Jersey
2021-09-15
Active, closed
A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate
NCT04909801Rheumatoid Arthritis
DrugsAbatacept·Humira·Adalimumab·Methotrexate
Bristol-Myers Squibb
Phase 3
338
California, Colorado, Maryland, Minnesota, New Jersey, New York, North Carolina, Oregon
2021-09-15
Active, closed
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
NCT05023551High Grade Glioma, Glioblastoma Multiforme
Sumitomo Pharma America, Inc.
Phase EARLY_PHASE1
39
California, Massachusetts, Missouri, New Jersey, New York, Utah
2021-09-08
Recruiting
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
NCT04486833Carcinoma, Non-Small Cell Lung
DrugsQuaratusugene ozeplasmid·Tagrisso·Osimertinib
Genprex, Inc.
Phase 1/2
158
California, Colorado, Illinois, Kentucky, Maryland, New Jersey, Ohio, Texas
2021-09-03
Active, closed
Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC
NCT04919811Non Small Cell Lung Cancer
DrugTaletrectinib
Nuvation Bio Inc.
Phase 2
217
California, Florida, Louisiana, Minnesota, New Jersey, Ohio, Tennessee, Texas
2021-09-01
Recruiting
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
NCT04913285Solid Tumor, Adult, Non-small Cell Lung Cancer, Melanoma
Pierre Fabre Medicament
Phase 1
400
California, Colorado, Florida, Minnesota, New Jersey, New York, Ohio, Tennessee
2021-08-04
Recruiting
RAPA-201 Therapy of Solid Tumors
NCT05144698Solid Tumor, Small Cell and Non-small Cell Lung Cancer, Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity
DrugsRAPA·Pembrolizumab
Rapa Therapeutics LLC
Phase 1/2
37
New Jersey
2021-08-01
Recruiting
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
NCT04817618C3G
DrugIptacopan
Novartis Pharmaceuticals
Phase 3
98
Colorado, Florida, Georgia, Indiana, Iowa, Maryland, Massachusetts, New Jersey
2021-07-28
Active, closed
Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing
NCT04798768Tachycardia, Ventricular, Arrhythmia, Ventricular
Boston Scientific Corporation
Not applicable
297
Arizona, Arkansas, Florida, Georgia, Kentucky, Minnesota, New Jersey, New York
2021-07-20
Recruiting
Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors
NCT04900818Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer
DrugGivastomig
I-Mab Biopharma US Limited
Phase 1
330
California, Colorado, Indiana, Massachusetts, New Jersey, New York, North Carolina, Tennessee
2021-06-29
Active, closed
Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer
NCT04725994Gastric Cancer
DrugsXelox·Irinotecan
Idience Co., Ltd.
Phase 1/2
87
California, Louisiana, Massachusetts, New Jersey
2021-06-28
Recruiting
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
NCT04802759Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
DrugsSamuraciclib·Ipatasertib·Giredestrant·Phesgo
Hoffmann-La Roche
Phase 1/2
316
California, Massachusetts, New Jersey, North Carolina, Pennsylvania, Tennessee
2021-06-22
Recruiting
A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
NCT04729114Prostate Cancer, Metastatic Castration Resistant Prostate Cancer, Metastatic Castration-sensitive Prostate Cancer
DrugsPRL-02·Enzalutamide·Prednisone·Dexamethasone
Astellas Pharma Global Development, Inc.
Phase 1
174
Arizona, California, Florida, Indiana, Kansas, Maryland, Nebraska, New Jersey
2021-06-14
Active, closed
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus
NCT04877691Systemic Lupus Erythematosus
DrugAnifrolumab
AstraZeneca
Phase 3
367
Alabama, Arizona, California, Colorado, Florida, Idaho, Michigan, New Jersey
2021-06-08
Active, closed
Valemetostat Tosylate (DS-3201b), an Enhancer of Zeste Homolog (EZH) 1/2 Dual Inhibitor, for Relapsed/Refractory Peripheral T-Cell Lymphoma (VALENTINE-PTCL01)
NCT04703192Relapsed/Refractory Peripheral T-Cell Lymphoma, Adult T Cell Leukemia/Lymphoma
DrugValemetostat Tosylate
Daiichi Sankyo
Phase 2
155
California, Colorado, Georgia, Illinois, Massachusetts, Minnesota, Missouri, New Jersey
2021-06-03
Recruiting
Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care
NCT04299022Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited
LifeNet Health
Observational
250
Florida, New Jersey, North Carolina, Virginia
2021-06-01
Recruiting
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
NCT04895709Cervical Cancer, Gastric/Gastroesophageal Junction Adenocarcinoma, Microsatellite Stable Colorectal Cancer, Non-Small-Cell Lung Cancer
DrugsImzokitug·Pumitamig·Docetaxel·Nivolumab
Bristol-Myers Squibb
Phase 1/2
1,109
California, Iowa, New Jersey, New York, Oregon, Tennessee, Texas
2021-05-27
Active, closed
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
NCT04873362Breast Cancer
DrugsAdo-trastuzumab emtansine·Trastuzumab emtansine·Herceptin·Tecentriq
Hoffmann-La Roche
Phase 3
1,188
Alabama, California, Florida, Georgia, Iowa, Maine, New Jersey, North Carolina
2021-05-04
Active, closed
A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)
NCT04853576Sickle Cell Disease, Hemoglobinopathies
Editas Medicine, Inc.
Phase 1/2
45
California, Colorado, Connecticut, Florida, Georgia, Illinois, Mississippi, New Jersey
2021-05-04
Recruiting
A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study
NCT04641247Ovarian Neoplasms, Breast Neoplasms
DrugNiraparib
GlaxoSmithKline
Phase 2
37
Arizona, California, Florida, Georgia, Illinois, Massachusetts, Michigan, New Jersey
2021-04-16
Active, closed
COMPASSION S3 Post-Approval Study
NCT04860765Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
Edwards Lifesciences
Observational
150
Alabama, California, Colorado, Illinois, Massachusetts, Minnesota, Missouri, New Jersey
2021-04-13
Recruiting
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
NCT04728893Hematologic Malignancies, Waldenstroms Macroglobulinaemia, Non-Hodgkins Lymphoma, Chronic Lymphocytic Leukaemia
DrugNemtabrutinib
Merck Sharp & Dohme LLC
Phase 2
490
Arkansas, California, Colorado, Kentucky, Minnesota, New Jersey, North Dakota, Texas
2021-04-05
Active, closed
Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)
NCT04675294Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
DrugsEvorpacept·Keytruda·Pembrolizumab
ALX Oncology Inc.
Phase 2
189
California, Florida, Georgia, Illinois, Maryland, Massachusetts, New Jersey, New York
2021-04-02
Active, closed
A Study to Assess the Safety and Tolerability of BMS-986158 Alone and in Combination With Either Ruxolitinib or Fedratinib in Participants With Blood Cancer (Myelofibrosis)
NCT04817007Myelofibrosis
DrugsBMS-986158·Fedratinib·Ruxolitinib
Bristol-Myers Squibb
Phase 1/2
216
California, Florida, Louisiana, Massachusetts, Michigan, New Jersey, North Carolina, Pennsylvania
2021-03-22
Active, closed
Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis
NCT04713475GM1 Gangliosidosis, GM1 Gangliosidosis, Type I, GM1 Gangliosidosis, Type 2, Beta-Galactosidase-1 (GLB1) Deficiency
Gemma Biotherapeutics
Phase 1/2
26
California, Minnesota, New Jersey, Pennsylvania
2021-03-17
Active, closed
Long-term Follow-Up for RGX-121
NCT04597385Mucopolysaccharidosis II
REGENXBIO Inc.
Observational
27
California, New Jersey, Pennsylvania
2021-03-14
Active, closed
A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma
NCT04722146Multiple Myeloma
DrugsNirogacestat·Teclistamab·Pomalidomide·Bortezomib
Janssen Research & Development, LLC
Phase 1
140
Alabama, California, Colorado, Georgia, Indiana, Missouri, New Jersey, New York
2021-03-12
Active, closed
A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma
NCT04594642B-cell Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, Follicular Lymphoma
DrugSurovatamig
AstraZeneca
Phase 1
226
Florida, Kentucky, New Jersey, North Carolina, Ohio, Pennsylvania, Texas, Wisconsin
2021-03-02
Active, closed
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
NCT04717414Myeloproliferative Disorders, Myelofibrosis, Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis
DrugLuspatercept
Celgene
Phase 3
313
California, Florida, Illinois, Kentucky, Michigan, Missouri, New Jersey, New York
2021-02-25
Active, closed
Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
NCT04279847Myelofibrosis, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome, Myeloproliferative Neoplasm
DrugRuxolitinib
Incyte Corporation
Phase 1
140
Alabama, Colorado, Florida, Georgia, Iowa, Missouri, New Jersey, New York
2021-02-23
Active, closed
A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
NCT04408638Diffuse Large B-cell Lymphoma
DrugsRituxumab·Glofitamab·Tocilizumab·Obinutuzumab
Hoffmann-La Roche
Phase 3
270
Alabama, California, Florida, Maryland, Massachusetts, Mississippi, New Jersey, New York
2021-02-23
By invitation
Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol
NCT05304728Severe Sepsis, Severe Sepsis Without Septic Shock
Beckman Coulter, Inc.
Observational
40,000
California, Georgia, Indiana, Missouri, New Jersey, North Carolina, Ohio
2021-02-15
Active, closed
Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)
NCT04657081Acute Myeloid Leukemia
DrugsDecitabine·Venclexta·Venetoclax
Taiho Oncology, Inc.
Phase 1/2
101
California, Connecticut, Florida, Illinois, Indiana, Massachusetts, Missouri, New Jersey
2021-02-09
Active, closed
MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb
NCT04649359Multiple Myeloma
DrugElranatamab
Pfizer
Phase 2
187
California, Florida, Georgia, Illinois, Kentucky, Louisiana, New Jersey, New York
2021-02-02
Active, closed
Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer
NCT04612751Advanced or Metastatic NSCLC
DrugsSabestomig·Volrustomig·Rilvegostomig·Dato-DXd
AstraZeneca
Phase 1
155
California, Missouri, New Jersey, Ohio, Pennsylvania, Texas, Virginia
2021-02-02
Recruiting
OssiMend BA in Posterolateral Instrumented Lumbar Fusion
NCT04775537Spinal Disease, Degenerative Disc Disease
Collagen Matrix
Observational
120
California, Connecticut, New Jersey, Oregon
2021-01-21
Active, closed
A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
NCT04628494Diffuse Large B-cell Lymphoma
DrugEpcoritamab
Genmab
Phase 3
483
Indiana, Kentucky, Michigan, Minnesota, New Jersey, North Carolina, Ohio, Texas
2021-01-13
Active, closed
A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
NCT04639219Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
DrugTrastuzumab deruxtecan
AstraZeneca
Phase 2
102
California, Indiana, Massachusetts, New Jersey, New York, Texas, Virginia
2020-12-30
Active, closed
A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers
NCT04626635Advanced Solid Tumors
DrugsMarlotamig·Trifluridine/Tipiracil·Cemiplimab·Bevacizumab
Regeneron Pharmaceuticals
Phase 1/2
548
California, Colorado, Florida, Illinois, Iowa, Michigan, New Jersey, New York
2020-12-21
Active, closed
A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder
NCT04658862Urinary Bladder Neoplasms
DrugsTAR-200·Cetrelimab·Gemcitabine·Cisplatin
Janssen Research & Development, LLC
Phase 3
518
California, Colorado, Florida, Georgia, Illinois, Michigan, Nebraska, New Jersey
2020-12-07
Recruiting
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
NCT04671771End Stage Renal Disease (ESRD), Kidney Failure, Chronic Renal Disease, Hemodialysis
W.L.Gore & Associates
Not applicable
133
Arizona, Florida, Georgia, Kentucky, Maryland, Massachusetts, New Jersey, New York
2020-12-03
Active, closed
PARADIGM: Amplatzer Valvular Plug for PVL Closure
NCT04489823Paravalvular Aortic Regurgitation
Abbott Medical Devices
Not applicable
200
Alabama, Georgia, Massachusetts, Minnesota, Missouri, Nebraska, New Jersey, New York
2020-12-01
Active, closed
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
NCT04623541Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome, Treatment-naïve High Risk Chronic Lymphocytic Leukemia
DrugsEpcoritamab·Pirtobrutinib·Lenalidomide·Venetoclax
Genmab
Phase 1/2
194
Alabama, California, Florida, Maryland, Massachusetts, Michigan, New Jersey, New York
2020-11-25
Active, closed
RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) With and Without Center Involved-Diabetic Macular Edema (CI-DME)
NCT04567550Diabetic Retinopathy (DR), Center-Involved Diabetic Macular Edema (CI-DME)
DrugAflibercept
AbbVie
Phase 2
139
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Jersey
2020-11-20
Active, closed
IN.PACT™ AV Access Post-Approval Study (PAS002)
NCT04543539Arteriovenous Fistula, Arteriovenous Fistula Stenosis, Arteriovenous Fistula Occlusion, Fistula
Medtronic
Observational
240
California, Connecticut, District of Columbia, Florida, Iowa, Michigan, Minnesota, New Jersey
2020-11-13
Active, closed
Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)
NCT04663347Diffuse Large B-Cell Lymphoma, Follicular Lymphoma
DrugsR-Ice·Rituximab and lenalidomide·Gemcitabine and oxaliplatin·Epcoritamab
Genmab
Phase 1/2
543
Alabama, California, Massachusetts, Michigan, New Jersey, New York, North Carolina, Texas
2020-11-03
Recruiting
The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation
NCT04494295Supratentorial Hemorrhage
Integra LifeSciences Corporation
Observational
500
California, Florida, Illinois, Maryland, Michigan, Missouri, New Jersey, New York
2020-10-23
By invitation
Long-term Follow-up of Subjects with Sickle Cell Disease Treated with Ex Vivo Gene Therapy
NCT04628585Sickle Cell Disease
Genetix Biotherapeutics Inc.
Observational
85
Alabama, California, Georgia, Illinois, Maryland, Minnesota, New Jersey, New York
2020-10-21
Active, closed
Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis
NCT04440189Osteoarthritis, Knee
GID BIO, Inc.
Phase 3
114
California, Florida, Louisiana, New Jersey, North Carolina, Ohio, Pennsylvania, Texas
2020-10-15
Active, closed
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions
NCT04538664Carcinoma, Non-Small-Cell Lung
DrugsAmivantamab·Pemetrexed·Carboplatin
Janssen Research & Development, LLC
Phase 3
308
California, District of Columbia, Florida, Georgia, Michigan, Missouri, New Jersey, New York
2020-10-13
Active, closed
A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)
NCT04546009Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer
DrugsGiredestrant·Palbociclib·Letrozole
Hoffmann-La Roche
Phase 3
992
California, Colorado, Florida, Hawaii, Maryland, Massachusetts, Missouri, New Jersey
2020-10-09
Active, closed
Impella ECP Early Feasibility Study
NCT04477603High-risk Percutaneous Coronary Intervention
Abiomed Inc.
Not applicable
100
Massachusetts, Michigan, New Jersey, Ohio
2020-10-09
Active, closed
AAV Gene Therapy Study for Subjects with PKU
NCT04480567Phenylketonuria (PKU)
BioMarin Pharmaceutical
Phase 1/2
100
Florida, New Jersey
2020-09-24
Active, closed
PF-07104091 as a Single Agent and in Combination Therapy
NCT04553133Small Cell Lung Cancer, Ovarian Cancer, Breast Cancer
DrugsPF-07104091·Palbociclib·Letrozole·Fulvestrant
Pfizer
Phase 2
157
Iowa, Kentucky, Massachusetts, New Jersey, New York, Virginia
2020-09-16
Active, closed
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)
NCT01817192Non-Small Cell Lung Cancer
Razor Genomics
Not applicable
420
California, Florida, Kentucky, Missouri, New Jersey, North Carolina, Oklahoma, Pennsylvania
2020-09-11
Recruiting
Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
NCT04299191High-grade Glioma, Solid Tumor, Unspecified, Child
DrugLAM561
Laminar Pharmaceuticals
Phase 1/2
28
Arkansas, Florida, New Jersey
2020-09-01
Recruiting
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)
NCT04419649Myelodysplastic Syndromes, Cytopenia
DrugElritercept
Takeda
Phase 2
160
Arkansas, California, Florida, Maryland, Michigan, New Jersey, New York, Pennsylvania
2020-08-19
Active, closed
A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors
NCT04482309Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer, Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
DrugTrastuzumab deruxtecan
AstraZeneca
Phase 2
477
California, Illinois, Indiana, Massachusetts, New Jersey, New York, North Carolina, Texas
2020-08-18
Active, closed
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
NCT04421963Ovarian Cancer, Breast Cancer
DrugOlaparib
AstraZeneca
Phase 3
185
Florida, Maryland, Michigan, Minnesota, New Jersey, New York, Pennsylvania, Rhode Island
2020-08-04
Active, closed
Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
NCT04390399Pancreatic Cancer
DrugsPD-L1 t-haNK·Irinotecan liposome·Leucovorin·Adrucil
ImmunityBio, Inc.
Phase 2
328
California, New Jersey, South Dakota
2020-07-21
Recruiting
Follow-up With Preimplantation Genetic Testing Patients
NCT04477863Infertility, Genetic Disease, IVF
Genomic Prediction Inc.
Observational
10,000
New Jersey
2020-07-11
Active, closed
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication
NCT042525731 Paravisceral Abdominal Aortic Aneurysm, 2 Juxtarenal Abdominal Aortic Aneurysm, 3 Pararenal Abdominal Aortic Aneurysm, 4 Complex Abdominal Aortic Aneurysms
Endologix
Not applicable
13
Alabama, District of Columbia, Georgia, Indiana, Missouri, New Jersey, New York, Oregon
2020-06-29
Active, closed
Episealer® Knee System IDE Clinical Study
NCT04000659Degenerative Lesion of Articular Cartilage of Knee
Episurf Medical Inc.
Not applicable
13
Arizona, California, Louisiana, New Jersey, New York, Ohio, Tennessee, Texas
2020-06-18
Active, closed
A Study to Assess Overall Response Rate by Inducing an Inflammatory Phenotype in Metastatic BReast cAnCEr With the Oncolytic Reovirus PeLareorEp in CombinaTion With Anti-PD-L1 Avelumab and Paclitaxel - BRACELET-1 Study
NCT04215146Breast Cancer Metastatic
DrugsPelareorep·Avelumab·Paclitaxel
Oncolytics Biotech
Phase 2
48
Florida, Illinois, Indiana, Louisiana, Missouri, New Jersey, New York, Ohio
2020-06-10
Recruiting
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
NCT04256317Myelodysplastic Syndromes, Acute Myeloid Leukemia, Myelodysplastic Syndrome/Neoplasm, Chronic Myelomonocytic Leukemia
DrugsVenclexta·Azacitidine·Venetoclax
Taiho Oncology, Inc.
Phase 2/3
316
California, Connecticut, Florida, Georgia, Massachusetts, New Jersey, New York, North Carolina
2020-05-21
Active, closed
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)
NCT04241185Urinary Bladder Neoplasms
DrugsMitomycin C·Fluorouracil·Adrucil·Keytruda
Merck Sharp & Dohme LLC
Phase 3
520
District of Columbia, Florida, Kentucky, Maryland, Missouri, New Jersey, New York, Ohio
2020-05-19
Active, closed
Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies
NCT04277637Mature B-Cell Malignancies
DrugsSonrotoclax·Zanubrutinib·Obinutuzumab
BeOne Medicines
Phase 1
437
California, Illinois, Kansas, Massachusetts, Minnesota, Nebraska, New Jersey, New York
2020-03-24
Recruiting
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
NCT04094610Locally Advanced Solid Tumors, Metastatic Solid Tumors, Lymphoma, Primary CNS Tumors
DrugRepotrectinib
Turning Point Therapeutics, Inc.
Phase 1/2
75
California, Colorado, Florida, Georgia, Maine, Massachusetts, Missouri, New Jersey
2020-03-12
Active, closed
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors
NCT04262466Select Advanced Solid Tumors
DrugBrenetafusp
Immunocore Ltd
Phase 1/2
410
California, Colorado, District of Columbia, Florida, Illinois, Iowa, Massachusetts, New Jersey
2020-02-25
Active, closed
A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease
NCT04293185Sickle Cell Disease
Genetix Biotherapeutics Inc.
Phase 3
35
Alabama, District of Columbia, Massachusetts, Minnesota, New Jersey, New York, North Carolina, Texas
2020-02-14
Active, closed
ANXA5 M2 Haplotyping in IVF Patients and Embryos
NCT04544462Infertility, Miscarriage, Recurrent, Pregnancy Complications
Genomic Prediction Inc.
Observational
500
New Jersey
2020-02-10
Recruiting
BS01 in Patients With Retinitis Pigmentosa
NCT04278131Retinitis Pigmentosa
DrugBS01
Bionic Sight LLC
Phase 1/2
20
New Jersey
2020-02-06
Active, closed
Optilume™ BPH Catheter System in Men With Symptomatic BPH
NCT04131907Benign Prostatic Hyperplasia
Urotronic Inc.
Not applicable
162
Arkansas, Colorado, Florida, Illinois, Louisiana, Maryland, Nevada, New Jersey
2020-02-05
By invitation
A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy
NCT05503927Pregnancy, Obesity, Overweight
Novo Nordisk A/S
Observational
2,701
Michigan, New Jersey
2020-02-01
Active, closed
An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis
NCT04130997Relapsing Multiple Sclerosis (RMS)
DrugUblituximab
TG Therapeutics, Inc.
Phase 3
1,100
California, Colorado, Florida, Illinois, Kansas, Michigan, Nevada, New Jersey
2019-11-18
Active, closed
NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory, Attention, Thinking)
NCT04148391Mild Cognitive Impairment, Mild Dementia, Parkinson Disease, Lewy Body Disease
Aptinyx
Phase 2
99
Arizona, California, Florida, Georgia, Michigan, Minnesota, New Jersey, New York
2019-11-14
Active, closed
A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Adult Patients With B-cell Non-Hodgkin Lymphoma Who Have Been Previously Treated With Other Cancer Therapies
NCT03888105B-cell Non-Hodgkin Lymphoma (B-NHL)
DrugOdronextamab
Regeneron Pharmaceuticals
Phase 2
515
Illinois, Iowa, Kentucky, Massachusetts, Minnesota, New Jersey, New York, North Carolina
2019-11-13
Recruiting
Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors
NCT04145622Advanced Solid Tumor, Malignant Solid Tumor
DrugIfinatamab Deruxtecan
Daiichi Sankyo
Phase 1/2
250
California, Colorado, Florida, Massachusetts, Michigan, Missouri, New Jersey, New York
2019-11-03
Active, closed
A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer
NCT04036682Non Small Cell Lung Cancer, EGFR Exon 20 Mutation
DrugZipalertinib
Cullinan Therapeutics Inc.
Phase 1/2
284
California, Florida, Massachusetts, Michigan, New Jersey, New York, Ohio, Oregon
2019-10-31
Active, closed
Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer
NCT04050436Cutaneous Squamous Cell Carcinoma, Advanced Cutaneous Squamous Cell Carcinoma, Metastatic Cutaneous Squamous Cell Carcinoma
DrugsVusolimogene Oderparepvec·Cemiplimab
Replimune, Inc.
Phase 2
231
California, Colorado, Florida, Georgia, New Jersey, New York, North Carolina, Ohio
2019-10-08
Active, closed
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
NCT04056247Stage IV Non-small Cell Lung Cancer, Stage IV Malignant Melanoma, Stage IV Small Cell Lung Cancer, Stage III Unresectable Non-Small Cell Lung Cancer
OncoHost Ltd.
Observational
10,000
Alabama, Florida, Illinois, Iowa, New Jersey, New York, Tennessee, Texas
2019-10-01
By invitation
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
NCT04093570Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes
DrugDecitabine
Taiho Oncology, Inc.
Phase 2
332
California, Florida, Illinois, Maryland, Michigan, Minnesota, New Jersey, New York
2019-09-30
Active, closed
A Study to Determine the Recommended Dose and Regimen and to Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination With Standard Treatments in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)
NCT03989414Multiple Myeloma
DrugsElotuzumab·Mezigdomide·Isatuximab·Carfilzomib
Celgene
Phase 1/2
424
Colorado, Florida, Georgia, Illinois, Massachusetts, Michigan, Minnesota, New Jersey
2019-09-30
Recruiting
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
NCT04104776Advanced Solid Tumor, Diffuse Large B Cell Lymphoma, Lymphoma, T-Cell, Mesothelioma, Malignant
DrugsTulmimetostat·Enzalutamide
Novartis Pharmaceuticals
Phase 1/2
300
Florida, Georgia, Illinois, Maryland, Massachusetts, Michigan, New Jersey, New York
2019-09-18
Active, closed
Portico Next Generation Approval Study
NCT04011722Symptomatic Severe Aortic Stenosis
Abbott Medical Devices
Not applicable
333
California, District of Columbia, Illinois, Indiana, Kansas, Michigan, Minnesota, New Jersey
2019-09-17
Active, closed
Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE III)
NCT04065490Dry Age-related Macular Degeneration
LumiThera, Inc.
Not applicable
96
California, Florida, Maryland, New Jersey, New York, North Carolina, Pennsylvania, Texas
2019-09-01
Active, closed
A Research Study in Children Born Small and Who Stayed Small. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day
NCT03878446Short Stature Children Born Small for Gestational Age (SGA)
DrugsNorditropin·Somapacitan
Novo Nordisk A/S
Phase 2
62
Alabama, California, Idaho, Minnesota, New Jersey, New York, Ohio, Oklahoma
2019-07-04
Active, closed
A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy
NCT04015141Pediatric Epileptic Syndrome, Partial-onset Seizures
DrugPerampanel
Eisai Inc.
Phase 2
100
California, Colorado, Florida, Georgia, Michigan, New Jersey, North Carolina, Ohio
2019-05-31
Active, closed
A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)
NCT03930953Lymphoma, Non-Hodgkin
DrugsValemetostat·Tafasitamab·Golcadomide·Obinutuzumab
Celgene
Phase 1/2
438
Arizona, Florida, Kansas, Minnesota, Missouri, New Jersey, Texas
2019-05-20
Active, closed
A Dose Escalation Study Evaluating CPI-818 in Relapsed/Refractory T-Cell Lymphoma
NCT03952078T-cell Lymphoma
DrugSoquelitinib
Corvus Pharmaceuticals, Inc.
Phase 1
151
California, Michigan, Missouri, New Jersey, Ohio, Pennsylvania
2019-05-03
Active, closed
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
NCT03872947Solid Tumor, Colorectal Cancer, Cholangiocarcinoma, Bladder Cancer
DrugsTRK-950·Imiquimod·Ramucirumab·Leucovorin
Toray Industries, Inc
Phase 1
138
Arizona, California, Louisiana, New Jersey, New York, Oregon, Texas, Virginia
2019-04-26
Recruiting
A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
NCT03802695Acute Myeloid Leukemia, Myelodysplastic Syndromes, Mixed Phenotype Acute Leukemia, Acute Lymphoblastic Leukemia
Orca Biosystems, Inc.
Phase 1
300
California, Florida, Georgia, Kansas, New Jersey, New York, Ohio, Texas
2019-04-08
Recruiting
An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia
NCT03813407Hyperkalaemia
DrugPumitamig
AstraZeneca
Phase 3
140
Alabama, Georgia, Maryland, Michigan, Missouri, New Jersey, New York, North Carolina
2019-04-02
Recruiting
Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma
NCT03761108Multiple Myeloma
DrugLinvoseltamab
Regeneron Pharmaceuticals
Phase 1/2
387
Florida, Georgia, Indiana, Kentucky, Michigan, New Jersey, New York, Ohio
2019-01-23
Active, closed
A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve
NCT03682536Myelodysplastic Syndromes
DrugsEpoetin Alfa·Luspatercept
Celgene
Phase 3
363
California, Connecticut, District of Columbia, Florida, Kentucky, Maryland, Missouri, New Jersey
2019-01-02
Active, closed
Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC
NCT03562637Triple Negative Breast Cancer
OBI Pharma, Inc
Phase 3
575
California, Florida, Illinois, Maryland, Michigan, New Jersey, Pennsylvania, Texas
2018-12-05
Active, closed
A Study to Assess Efficacy and Safety of RT001 in Subjects With Infantile Neuroaxonal Dystrophy
NCT03570931Infantile Neuroaxonal Dystrophy
Biojiva LLC
Phase 2/3
19
California, New Jersey
2018-11-05
Active, closed
A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia
NCT03589326Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
DrugsPonatinib·Imatinib·Cytarabine·Vincristine
Takeda
Phase 3
245
Alabama, California, Georgia, Indiana, Kansas, Maryland, New Jersey, New York
2018-10-04
Recruiting
Tolerability Study of Trichostatin A In Subjects With Relapsed or Refractory Hematologic Malignancies
NCT03838926Relapsed or Refractory Hematologic Malignancies
DrugTrichostatin A
Vanda Pharmaceuticals
Phase 1
42
District of Columbia, Indiana, New Jersey, Washington
2018-09-27
Active, closed
CAMPSIITE™ RGX-121 Gene Therapy in Subjects With MPS II (Hunter Syndrome)
NCT03566043Mucopolysaccharidosis Type II (MPS II)
REGENXBIO Inc.
Phase 2/3
48
California, New Jersey, Pennsylvania
2018-09-27
Recruiting
Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients
NCT03567889Melanoma Stage IIIB, Melanoma Stage IIIC, Melanoma Stage IIID
DrugDaromun
Philogen S.p.A.
Phase 3
186
Arizona, California, Florida, Georgia, Illinois, Iowa, Minnesota, New Jersey
2018-09-20
Active, closed
Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)
NCT03393884Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
DrugsIMNN-001·Paclitaxel·Carboplatin
Imunon
Phase 1/2
130
Alabama, California, Florida, Massachusetts, Missouri, New Jersey, New York, Oklahoma
2018-09-05
Active, closed
Early Feasibility Evaluation of the AccuCinch® Ventricular Restoration System in Patients With Heart Failure and Reduced Ejection Fraction
NCT03533517Heart Failure, Cardiomyopathy, Dilated
Ancora Heart, Inc.
Not applicable
22
California, Georgia, Kentucky, Louisiana, Minnesota, Nebraska, New Jersey, New York
2018-08-23
Recruiting
Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
NCT03523416Heart Failure
Edwards Lifesciences
Not applicable
90
California, Colorado, Florida, Indiana, Kansas, Minnesota, New Jersey, New York
2018-07-31
Active, closed
A Global Study to Assess the Effects of Osimertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer (LAURA)
NCT03521154Non Small Cell Lung Cancer (Stage III)
DrugOsimertinib
AstraZeneca
Phase 3
216
California, Georgia, New Jersey, Utah, Wisconsin
2018-07-19
Active, closed
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
NCT03451851Psoriasis
DrugsEtanercept·Guselkumab
Janssen Research & Development, LLC
Phase 3
120
California, Georgia, Illinois, New Jersey, New York, Ohio, Texas
2018-07-11
Active, closed
ERG Components in Schizophrenia and Bipolar Disorder Type I
NCT03788811Schizophrenia, Bipolar I Disorder
diaMentis Inc.
Observational
300
California, Florida, Massachusetts, New Jersey, New York, Texas
2018-07-05
Active, closed
Clinical Study of Edwards Cardioband FIT Valve Repair System
NCT03382457Tricuspid Regurgitation
Edwards Lifesciences
Not applicable
75
Illinois, Minnesota, New Jersey, New York, Oregon, Pennsylvania, Texas, Utah
2018-07-01
Active, closed
ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease
NCT03499964Urethral Stricture
Urotronic Inc.
Not applicable
127
Arizona, Arkansas, Florida, Iowa, Maryland, Minnesota, Nebraska, New Jersey
2018-06-22
Recruiting
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
NCT03556228Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer, Non-Small Cell Lung Cancer
VM Oncology, LLC
Phase 1/2
242
California, Connecticut, District of Columbia, Florida, New Jersey, New Mexico, New York, Ohio
2018-06-08
Active, closed
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
NCT03491683Glioblastoma
DrugsINO-9012·Cemiplimab·Temozolomide
Inovio Pharmaceuticals
Phase 1/2
52
California, Florida, Georgia, Massachusetts, Michigan, New Jersey, New York, North Carolina
2018-05-31
Active, closed
Multi-Center Study of Sensory Stimulation to Improve Brain Function
NCT03556280Alzheimer Disease, Cognitive Impairment, Mild Cognitive Impairment, Dementia Alzheimers
Cognito Therapeutics, Inc.
Not applicable
60
Florida, Massachusetts, New Jersey
2018-04-24
Active, closed
A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
NCT03462719Leukemia, Lymphocytic, Chronic, B-Cell
DrugsChlorambucil·Ibrutinib·Obinutuzumab·Venetoclax
Janssen Research & Development, LLC
Phase 3
211
Kentucky, New Jersey, North Carolina
2018-04-17
Active, closed
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
NCT03348995Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Miach Orthopaedics
Not applicable
250
California, Florida, Georgia, Louisiana, Maryland, Massachusetts, New Jersey, Rhode Island
2018-04-17
Active, closed
A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer
NCT03473743Urothelial Carcinoma
DrugsErdafitinib·Cetrelimab·Cisplatin·Carboplatin
Janssen Research & Development, LLC
Phase 1/2
125
Colorado, Kentucky, Maryland, New Jersey, New York, North Carolina, Ohio, Pennsylvania
2018-04-05
Active, closed
A Study of Combination Therapy With Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Participants With Relapsed or Refractory Multiple Myeloma
NCT03314181Multiple Myeloma
DrugsVenclexta·Bortezomib·Daratumumab·Venetoclax
AbbVie
Phase 2
156
Colorado, Florida, Georgia, Illinois, Massachusetts, New Jersey, New York, North Carolina
2018-04-02
Recruiting
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
NCT03424005Metastatic Breast Cancer
DrugsAtirmociclib·Ipatasertib·Giredestrant·Inavolisib
Hoffmann-La Roche
Phase 1/2
1,132
California, Colorado, Florida, Illinois, Minnesota, Nevada, New Jersey, New York
2018-03-30
Active, closed
Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
NCT03257033Locally Advanced Pancreatic Cancer
DrugsAbraxane·Nab-paclitaxel·Gemcitabine
RenovoRx
Phase 3
190
California, District of Columbia, Florida, Iowa, Maryland, Nebraska, New Hampshire, New Jersey
2018-03-12
Recruiting
Collection of Sputum and Labeling for Lung Cancer
NCT03457415Lung Cancer
bioAffinity Technologies Inc.
Observational
500
New Jersey, New Mexico, Texas
2018-03-01
Active, closed
PRospective Multiple Myeloma Impact Study
NCT02911571Multiple Myeloma
SkylineDx
Not applicable
250
District of Columbia, Georgia, New Jersey, New York, North Carolina, Wisconsin
2018-02-27
Active, closed
A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL
NCT03336333Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugsVenclyxto·Bendamustine·Venclexta·Zanubrutinib
BeiGene
Phase 3
590
Georgia, Illinois, Massachusetts, Missouri, Nevada, New Jersey, New York, North Carolina
2017-10-31
Active, closed
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
NCT03153449Primary Knee Arthroplasty
DePuy Orthopaedics
Not applicable
400
California, Colorado, Connecticut, Florida, Kentucky, Mississippi, New Hampshire, New Jersey
2017-09-19
Active, closed
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
NCT02962414Tuberous Sclerosis Complex
DrugEverolimus
Novartis Pharmaceuticals
Phase 3
206
Arizona, California, Colorado, Connecticut, Illinois, Minnesota, New Jersey, Ohio
2017-08-23
Active, closed
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma
NCT02704858Glioblastoma Multiforme
DrugPerillyl alcohol
Neonc Technologies, Inc.
Phase 1/2
49
California, Georgia, Louisiana, New Jersey, New York, North Carolina, Ohio, Texas
2017-08-01
Active, closed
JOURNEY II XR Safety and Effectiveness PMCF
NCT03136887Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee, Knee Osteoarthritis, Degenerative Arthritis Peripheral Joint
Smith & Nephew, Inc.
Observational
176
California, Florida, Illinois, Maryland, Michigan, Nevada, New Jersey, New York
2017-07-28
By invitation
LTS of Siliq vs. Other Therapies Treating of Adults With Moderate-to-Severe Psoriasis
NCT03254667Psoriasis
DrugBrodalumab
Bausch Health Americas, Inc.
Observational
3,500
New Jersey
2017-07-25
Active, closed
Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.
NCT03229200Lymphoma, B-Cell, Lymphoma, Non-Hodgkin, Leukemia, B-cell, Graft Vs Host Disease
DrugIbrutinib
Pharmacyclics Switzerland GmbH
Phase 4
297
California, Georgia, Illinois, Kentucky, Massachusetts, Michigan, Nevada, New Jersey
2017-05-22
Active, closed
Prospective G7 Dual Mobility Total Hip PMCF
NCT03308929Clinical Outcomes, Functional Outcomes, Radiological Outcomes, Survivorship
Zimmer Biomet
Observational
250
New Jersey, New Mexico, North Carolina, Oregon, Virginia
2017-02-28
Active, closed
Trident II Tritanium Acetabular Shell Outcomes Study
NCT02999009Arthroplasty, Replacement, Hip
Stryker Orthopaedics
Not applicable
383
Arizona, Florida, Illinois, Louisiana, Michigan, New Jersey, New York, North Carolina
2017-01-20
Active, closed
14022 ATTUNE Cementless RP Clinical Performance Evaluation
NCT02839850Osteoarthritis
DePuy Orthopaedics
Not applicable
540
Colorado, Florida, New Hampshire, New Jersey, New York, North Carolina, Tennessee, Texas
2016-09-01
Recruiting
Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
NCT02781883Acute Myeloid Leukemia (AML)
DrugsVentoclax·Decitabine
Bio-Path Holdings, Inc.
Phase 2
108
California, Georgia, Kansas, New Jersey, New York, Texas, West Virginia
2016-05
Recruiting
RHythmia mAPping and Signal acquisitiOn for Data analYsis (RHAPSODY)
NCT03053141Cardiac Arrythmias
Boston Scientific Corporation
Observational
100
Alabama, Idaho, Massachusetts, New Hampshire, New Jersey
2016-05
Active, closed
Randomized Controlled Trial of CAN-2409 Immunotherapy During Active Surveillance for Prostate Cancer (ULYSSES)
NCT02768363Prostate Cancer
DrugsAglatimagene besadenovec·Valacyclovir
Candel Therapeutics, Inc.
Phase 2
187
Colorado, Illinois, Louisiana, Maryland, Missouri, Nevada, New Jersey, New York
2016-05
Active, closed
A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL
NCT02717624Mantle Cell Lymphoma (MCL)
DrugAcalabrutinib
Acerta Pharma BV
Phase 1
72
Kentucky, Michigan, New Jersey, New York, Ohio, Tennessee, Texas, Washington
2016-04-20
Active, closed
DS-3201b in Participants With Lymphomas
NCT02732275Lymphoma, Malignant, Non-hodgkin Lymphoma
DrugValemetostat Tosylate
Daiichi Sankyo Co., Ltd.
Phase 1
100
California, Connecticut, Georgia, Massachusetts, New Jersey, New York, North Carolina, Ohio
2016-03-31
Active, closed
Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study
NCT02584933ALK Positive Malignancies
DrugCeritinib
Novartis Pharmaceuticals
Phase 4
233
Arkansas, California, Colorado, Maryland, New Jersey
2015-12-11
Active, closed
Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)
NCT02542293Non Small Cell Lung Carcinoma NSCLC
DrugsTremelimumab·Durvalumab·Pemetrexed·Gemcitabine
AstraZeneca
Phase 3
953
California, Kentucky, New Jersey, New Mexico, New York, Ohio, Pennsylvania, Texas
2015-11-03
Recruiting
Selinexor and Backbone Treatments of Multiple Myeloma Patients
NCT02343042Multiple Myeloma
DrugsIxazomib·Elotuzumab·Mezigdomide·Clarithromycin
Karyopharm Therapeutics Inc
Phase 1/2
300
Arizona, California, Colorado, Massachusetts, Nebraska, New Jersey, New York, North Carolina
2015-10
Active, closed
Triathlon Tritanium Cone Augments Outcomes Study
NCT02521103Arthroplasty, Replacement, Knee
Stryker Orthopaedics
Not applicable
254
Florida, Illinois, Kentucky, Michigan, Missouri, New Jersey, Oklahoma, Washington
2015-08
Active, closed
An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma
NCT02213926Mantle Cell Lymphoma (MCL)
DrugAcalabrutinib
Acerta Pharma BV
Phase 2
124
Florida, Illinois, Massachusetts, New Jersey, New York, Texas, Washington
2015-03-02
Active, closed
Edwards EVOQUE Eos MISCEND Study
NCT02718001Mitral Valve Regurgitation (Degenerative or Functional)
Edwards Lifesciences
Not applicable
123
California, Georgia, Illinois, Indiana, Massachusetts, New Jersey, New York, Ohio
2015-02-06
Active, closed
Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma
NCT02180711Non Hodgkin Lymphoma
DrugsAcalabrutinib·Lenalidomide·Rituximab
Acerta Pharma BV
Phase 1/2
113
Arizona, California, Florida, Illinois, Kentucky, Louisiana, Michigan, New Jersey
2014-12-29
Active, closed
Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
NCT02227251Diffuse Large B-cell Lymphoma
DrugSelinexor
Karyopharm Therapeutics Inc
Phase 2
244
Arizona, California, Florida, Illinois, Kentucky, Massachusetts, New Jersey, New York
2014-11
Active, closed
A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors
NCT02099058Advanced Solid Tumors Cancer
DrugsTelisotuzumab vedotin·Erlotinib·Osimertinib·Nivolumab
AbbVie
Phase 1
237
Arizona, California, Colorado, Illinois, Massachusetts, Michigan, Missouri, New Jersey
2014-01-15
Active, closed
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
NCT01892722Multiple Sclerosis
DrugsAvonex·Fingolimod
Novartis Pharmaceuticals
Phase 3
240
Alabama, California, Florida, Massachusetts, Michigan, New Jersey, Pennsylvania, Utah
2013-07-26
Active, closed
An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis
NCT01357668Juvenile Idiopathic Arthritis
Bristol-Myers Squibb
Observational
800
Arkansas, New Jersey, Ohio
2013-01-30
Recruiting
Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
NCT01429389Down Syndrome, Fetal Aneuploidy
Sequenom, Inc.
Observational
2,000
Alabama, California, Illinois, Iowa, Michigan, New Jersey, South Carolina
2011-05
Active, closed
Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System
NCT01480440Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture
Zimmer Biomet
Observational
200
California, Kentucky, New Jersey, Pennsylvania
2011-01
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 6 October 2026. https://priyalifescience.com/clinical-trials-usa/state/new-jersey?page=2

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,118 studies in total at the last sync on 06 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 782 of those studies with a site in New Jersey.

How many clinical trials are recruiting in New Jersey?

416 of the 782 studies on this page are recruiting new participants as of the 06 Oct 2026, 03:16 UTC sync. A further 25 have not yet opened recruitment, 317 are active but closed to new participants, and 24 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.