ANXA5 M2 Haplotyping in IVF Patients and Embryos

Condition(s) studied

Investigational drug(s) / intervention(s)

M2 Test: DNA will be extracted from saliva samples obtained from participants. Genetic testing will be performed to screen for the M2 mutation and determine the carrier status of each patient and partner.

Study summary

This study aims to characterize the association between history of pregnancy complications and M2 carrier status in IVF patients and the utility of M2 haplotype preimplantation genetic testing (PGT) in embryos produced by carrier couples. Participants in this study will be screened for the M2 variant. History of pregnancy complications and miscarriages will be studied in order to determine potential associations with M2 carrier-ship.

Eligibility

Primary outcome measure(s)

• M2 Haplotype frequency — 1 month
  Frequency of carriers of the M2 haplotype attending an IVF center for infertility treatment.

Trial sites (1)

More Genomic Prediction Inc. trials in the USA

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