Relutrigine is named as an intervention in 2 current clinical trials in our USA and UK registers. None are recruiting at the moment. The most common phase is Phase 2/3. The lead sponsor is Praxis Precision Medicines. The most-studied condition is SCN2A Encephalopathy.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine
NCT07010471 · ClinicalTrials.gov ↗ · Developmental and Epileptic Encephalopathy 1
|
Phase 3 | Active, closed | Praxis Precision Medicines | USA |
|
A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)
NCT05818553 · ClinicalTrials.gov ↗ · SCN2A Encephalopathy, SCN8A Encephalopathy
|
Phase 2/3 | Active, closed | Praxis Precision Medicines | UK, USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Lead sponsor | Trials |
|---|---|
| Praxis Precision Medicines | 2 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 2 | 0 |
| Clinical trials in UK | 1 | 0 |
A trial with sites in more than one country appears in each of those registers.
2 current trials in our USA and UK registers name Relutrigine (also registered as PRAX-562) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.
Not at the moment. None of the 2 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.
The lead sponsor is Praxis Precision Medicines. The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Relutrigine works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Relutrigine works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Relutrigine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.