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Trackers› Clinical trials› Kansas
Clinical trial register · United States · industry-sponsored

Clinical Trials in Kansas, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9118 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 06 Oct 2026, 03:16 UTC
9118
Studies in scope
industry-sponsored, all four open statuses
4945
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 5290 Florida 4430 Illinois 2481 Georgia 2368 Arizona 2238
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca40 Janssen Research & Development, LLC22 Novartis Pharmaceuticals20 Eli Lilly and Company18 Pfizer15
State
California5290 Florida4430 Illinois2481 Georgia2368 Arizona2238
All 51 states
Target enrolment
to

Trials with a site in Kansas

743 of 9118 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.
NCT05592002Sleep Apnea, Obstructive
Nyxoah S.A.
Not applicable
124
Colorado, Florida, Indiana, Iowa, Kansas, Massachusetts, New York, Pennsylvania
2022-12-28
Recruiting
Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)
NCT05549297Advanced Melanoma
DrugTebentafusp
Immunocore Ltd
Phase 3
540
Arizona, Florida, Georgia, Kansas, Kentucky, Massachusetts, Minnesota, Missouri
2022-12-19
Active, closed
CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)
NCT05681351Severe Hypertriglyceridemia
DrugOlezarsen
Ionis Pharmaceuticals, Inc.
Phase 3
885
California, Florida, Georgia, Illinois, Indiana, Kansas, Kentucky, Louisiana
2022-12-13
Active, closed
Spectacle Lens Visual Acuity Assessments Study
NCT05650190Myopia, Myopia Progression, Juvenile Myopia
SightGlass Vision, Inc.
Not applicable
51
Florida, Kansas, Missouri, New York, Texas, Utah
2022-12-08
Recruiting
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
NCT05579366High Grade Epithelial Ovarian Cancer, High Grade Serous Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
DrugsRina-S·Bevacizumab·Carboplatin·Pembrolizumab
Genmab
Phase 1/2
884
Arizona, California, Florida, Georgia, Kansas, Maryland, Massachusetts, Michigan
2022-12-07
Recruiting
A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors
NCT05584670Solid Tumor
DrugsSAR445877·ADG126·Zirabev·Erbitux
Sanofi
Phase 1/2
542
Delaware, Iowa, Kansas, Michigan, New Jersey, New York, Rhode Island, Texas
2022-11-29
Active, closed
Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation
NCT05609578Advanced NSCLC, Metastatic Lung Cancer
DrugAdagrasib
Mirati Therapeutics Inc.
Phase 2
90
California, Colorado, Florida, Illinois, Kansas, Massachusetts, Michigan, Minnesota
2022-11-22
Active, closed
Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis
NCT05556096Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc.
Phase 3
260
California, Colorado, District of Columbia, Florida, Georgia, Illinois, Kansas, Kentucky
2022-11-21
Recruiting
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
NCT05498428Carcinoma, Non-small-Cell Lung
DrugsDirect Anticoagulant·LMWH·DOAC·Low molecular weight heparin
Janssen Research & Development, LLC
Phase 2
520
California, District of Columbia, Florida, Kansas, Maryland, Massachusetts, Missouri, New Jersey
2022-11-11
Active, closed
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
NCT05583227Eosinophilic Esophagitis
DrugTezepelumab
AstraZeneca
Phase 3
368
Arizona, Arkansas, California, Colorado, Florida, Illinois, Iowa, Kansas
2022-11-10
Active, closed
An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome
NCT05367960Fragile X Syndrome
Tetra Discovery Partners
Phase 3
314
California, Colorado, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2022-11-01
Active, closed
A Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV
NCT05481151Polycythemia Vera
DrugBesremi
PharmaEssentia
Phase 3
111
Florida, Indiana, Kansas, Kentucky, Louisiana, Maryland, Missouri, New Jersey
2022-10-26
Recruiting
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
NCT05253651Colorectal Neoplasms
DrugsTucatinib·Erbitux·Herceptin·Avastin
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
400
Arizona, California, Colorado, Florida, Georgia, Kansas, Kentucky, Minnesota
2022-10-24
Active, closed
A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)
NCT05540860Duchenne Muscular Dystrophy
DrugsSevasemten 1·Sevasemten 2·Sevasemten 3
Edgewise Therapeutics, Inc.
Phase 2
76
Arkansas, California, Colorado, Florida, Georgia, Iowa, Kansas, Maryland
2022-10-24
Active, closed
Phase I Trial to Evaluate VLP Peanut in Healthy and Peanut Allergic Subjects
NCT05476497Peanut Allergy
Allergy Therapeutics
Phase 1
46
Arizona, Florida, Kansas, Massachusetts, Minnesota, Missouri, New York, Ohio
2022-10-17
Active, closed
A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment
NCT05455320Multiple Myeloma
DrugsTalquetamab·Pomalidomide·Daratumumab·Dexamethasone
Janssen Research & Development, LLC
Phase 3
864
Arizona, Arkansas, Connecticut, District of Columbia, Florida, Illinois, Kansas, Louisiana
2022-10-13
Recruiting
Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC
NCT05491525Neurogenic Detrusor Overactivity
DrugVibegron
Urovant Sciences GmbH
Phase 2/3
71
Arkansas, California, Colorado, Florida, Kansas, Louisiana, New York, North Carolina
2022-10-12
Active, closed
Study of Oral MRT-2359 in Selected Cancer Patients
NCT05546268NSCLC, SCLC, High Grade Neuroendocrine Cancer, DLBCL
DrugMRT-2359
Monte Rosa Therapeutics, Inc
Phase 1/2
174
Arizona, California, Connecticut, Kansas, Massachusetts, Michigan, Missouri, New York
2022-10-12
Active, closed
Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies
NCT05397496B-cell Non-Hodgkin Lymphoma (B-NHL), B-cell Acute Lymphoblastic Leukemia (B-ALL)
DrugPIT565
Novartis Pharmaceuticals
Phase 1
61
Florida, Illinois, Kansas, New York, Oregon
2022-10-03
Active, closed
A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease
NCT05347095Fistulizing Crohns Disease, Perianal Crohns Disease
DrugGuselkumab
Janssen-Cilag Ltd.
Phase 3
288
Alabama, Connecticut, Florida, Kansas, Kentucky, Missouri, New York, Oklahoma
2022-09-27
Recruiting
Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
NCT05327114Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
DrugNipocalimab
Janssen Research & Development, LLC
Phase 2/3
201
Colorado, Florida, Georgia, Kansas, Maryland, Massachusetts, Michigan, Missouri
2022-09-23
Active, closed
Study of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Follicular Lymphoma
NCT05371093Relapsed/Refractory Follicular Lymphoma
DrugsAxi-cel·Axicabtagene Ciloleucel·Bendamustine·Vincristine
Kite, A Gilead Company
Phase 3
231
California, Florida, Kansas, Maryland, Massachusetts, North Carolina, Pennsylvania, Tennessee
2022-09-22
Recruiting
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
NCT05519085Relapsed or Refractory Multiple Myeloma
DrugsMezigdomide·Velcade·Pomalidomide·Bortezomib
Celgene
Phase 3
810
California, Colorado, Connecticut, Florida, Georgia, Kansas, Louisiana, Maryland
2022-09-20
Active, closed
MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study
NCT05409989Intracranial Aneurysm
Microvention-Terumo, Inc.
Not applicable
154
Florida, Hawaii, Iowa, Kansas, Kentucky, Louisiana, Maryland, Massachusetts
2022-09-20
Active, closed
Phase 2a to Evaluate PL-8177 in Subjects with Active Ulcerative Colitis (UC)
NCT05466890Ulcerative Colitis, Ulcerative Colitis Acute, Ulcerative, Ulcerative Colitis Flare
Palatin Technologies, Inc
Phase 2
16
Arizona, California, Florida, Kansas, Louisiana, New Jersey, New York, Pennsylvania
2022-09-15
Active, closed
XIENCE Skypoint Large Vessel Post Approval Study
NCT05423379Coronary Artery Disease
Abbott Medical Devices
Observational
102
Arkansas, Florida, Kansas, Nebraska, New York, Pennsylvania, South Carolina, Texas
2022-09-14
Active, closed
A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
NCT05528510Colitis, Ulcerative
DrugsGuselkumab 1·Guselkumab 2·Guselkumab 3
Janssen Research & Development, LLC
Phase 3
418
Arizona, California, Colorado, Florida, Georgia, Kansas, Michigan, New York
2022-09-13
Recruiting
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
NCT05489211Endometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer, Ovarian Cancer
DrugsPrednisone/Prednisolone·Volrustomig·Rilvegostomig·Dato-DXd
AstraZeneca
Phase 2
454
California, Indiana, Kansas, Massachusetts, Michigan, New Jersey, New Mexico, New York
2022-09-06
Active, closed
Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device
NCT04839705Wide Neck Bifurcation Intracranial Aneurysms
Microvention-Terumo, Inc.
Not applicable
195
Florida, Hawaii, Iowa, Kansas, Kentucky, Louisiana, Maryland, Massachusetts
2022-08-24
Active, closed
Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar Spine
NCT05516992Lumbar Degenerative Disc Disease
Spine BioPharma, Inc
Phase 3
417
Alabama, Arizona, California, Florida, Georgia, Idaho, Indiana, Kansas
2022-08-19
Active, closed
A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)
NCT05327530Locally Advanced or Metastatic Urothelial Carcinoma
DrugsAvelumab·Sacituzumab Govitecan
EMD Serono Research & Development Institute, Inc.
Phase 2
256
Idaho, Kansas, Maryland, Missouri, Washington, Wisconsin
2022-08-17
Active, closed
GammaTile and Stupp in Newly Diagnosed GBM
NCT05342883Glioblastoma
GT Medical Technologies, Inc.
Phase 4
61
Arizona, California, Florida, Georgia, Illinois, Indiana, Kansas, Michigan
2022-08-17
Recruiting
Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V
NCT05268289Lupus Nephritis
DrugIptacopan
Novartis Pharmaceuticals
Phase 2
240
Arizona, California, Colorado, Florida, Illinois, Kansas, Louisiana, Maryland
2022-08-10
Active, closed
A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer
NCT05388669Advanced or Metastatic Non-small Cell Lung Cancer
DrugsLazertinib·Amivantamab
Janssen Research & Development, LLC
Phase 3
418
California, Colorado, Florida, Kansas, Michigan, New Jersey, New York, Oregon
2022-08-05
Active, closed
Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome
NCT05349214Sjogren Syndrome
DrugIanalumab
Novartis Pharmaceuticals
Phase 3
506
California, Florida, Georgia, Illinois, Kansas, Massachusetts, New Mexico, New York
2022-08-04
Active, closed
A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Doublet in Small Cell Lung Cancer
NCT05566041Carcinoma, Small Cell Lung
DrugsRRx-001·Cisplatin/Carboplatin·Etoposide
EpicentRx, Inc.
Phase 3
292
Florida, Kansas
2022-08-01
Active, closed
Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF
NCT05389215Idiopathic Pulmonary Fibrosis
Daewoong Pharmaceutical Co. LTD.
Phase 2
102
Arizona, California, Illinois, Kansas, Massachusetts, Michigan, Missouri, North Carolina
2022-07-29
Active, closed
Noninterventional Study Evaluating Parkinson's Disease Diary Use
NCT05363046Parkinson's Disease
BlueRock Therapeutics
Observational
194
Arizona, California, Colorado, Florida, Illinois, Kansas, Kentucky, Massachusetts
2022-07-29
Active, closed
LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
NCT05321420Idiopathic Pulmonary Fibrosis
DrugsDeupirfenidone·Pirfenidone
PureTech
Phase 2
240
Alabama, California, Connecticut, Florida, Georgia, Indiana, Kansas, North Carolina
2022-07-22
Active, closed
A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)
NCT05458297Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Follicular Lymphoma, Richter Transformation Lymphoma
DrugsZilovertamab vedotin·Nemtabrutinib
Merck Sharp & Dohme LLC
Phase 2
189
Alaska, Arizona, Colorado, Illinois, Kansas, Kentucky, Maryland, Massachusetts
2022-07-21
Recruiting
A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis
NCT05265273Myasthenia Gravis
DrugNipocalimab
Janssen Research & Development, LLC
Phase 2/3
12
Arizona, California, Colorado, Florida, Kansas, Michigan, Pennsylvania
2022-07-20
Recruiting
A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
NCT05361174Unresectable Melanoma, Metastatic Melanoma, Stage III Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
Iovance Biotherapeutics, Inc.
Phase 1/2
53
California, Florida, Kansas, Kentucky, New York, Ohio, Pennsylvania, Wisconsin
2022-07-20
Recruiting
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
NCT06426628Pulmonary Nodule, Solitary, Lung Cancer
Veracyte, Inc.
Observational
2,400
Connecticut, Florida, Illinois, Kansas, Kentucky, Louisiana, Maryland, Massachusetts
2022-07-18
Active, closed
A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)
NCT05392114Hereditary Angioedema
DrugDonidalorsen
Ionis Pharmaceuticals, Inc.
Phase 3
154
Arizona, California, Florida, Kansas, Massachusetts, Michigan, Missouri, North Carolina
2022-07-13
Active, closed
A Study of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies
NCT05379634Myositis
DrugNipocalimab
Janssen Research & Development, LLC
Phase 2
36
Arizona, California, Florida, Georgia, Kansas, Maryland, Massachusetts, Michigan
2022-07-05
Active, closed
Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis
NCT04991116Psoriatic Arthritis
Sun Pharmaceutical Industries Limited
Phase 3
529
Alabama, Arizona, California, Florida, Georgia, Illinois, Kansas, Missouri
2022-06-30
Active, closed
Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer
NCT05257408Ovarian Neoplasm, Fallopian Tube Neoplasms, Peritoneal Neoplasms
DrugsNab-paclitaxel /m^2·Relacorilant
Corcept Therapeutics
Phase 3
381
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2022-06-29
Active, closed
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
NCT05285553Myopia
CooperVision, Inc.
Not applicable
900
Alabama, California, Florida, Illinois, Indiana, Kansas, Massachusetts, Minnesota
2022-06-25
Recruiting
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
NCT05462106Amyloid Plaque, Beta-Amyloid, DSAD, Prodromal Alzheimer's Disease
AC Immune SA
Phase 1/2
304
Arizona, Florida, Indiana, Kansas, Massachusetts, Missouri, North Carolina, Tennessee
2022-06-21
Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
NCT05172960Aortic Stenosis, Severe
Edwards Lifesciences
Not applicable
1,234
California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Kansas
2022-06-20
Recruiting
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
NCT05429632Adult Acute Myeloid Leukemia
Priothera SAS
Phase 3
366
Alabama, Arizona, California, Colorado, Florida, Georgia, Iowa, Kansas
2022-06-16
Recruiting
BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL
NCT05370430Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
PeproMene Bio, Inc.
Phase 1
36
California, Kansas, Minnesota, North Carolina, Washington
2022-06-13
Recruiting
A Study of ASP3082 in Adults With Advanced Solid Tumors
NCT05382559Solid Tumor
DrugsNanoparticle albumin-bound-paclitaxel·Setidegrasib·Liposomal Irinotecan·Fluorouracil
Astellas Pharma Inc
Phase 1
681
California, Colorado, Connecticut, District of Columbia, Florida, Kansas, Massachusetts, Michigan
2022-06-08
Recruiting
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
NCT05365581Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma
DrugsASP2138·Ramucirumab·Fluorouracil·Leucovorin
Astellas Pharma Global Development, Inc.
Phase 1
398
California, Illinois, Kansas, New Jersey, New York, North Carolina, Texas, Washington
2022-06-07
Active, closed
A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer
NCT05318573Advanced Urothelial Carcinoma, Advanced Non Small Cell Lung Cancer
DrugsFF-10832·Keytruda·Pembrolizumab
Fujifilm Pharmaceuticals U.S.A., Inc.
Phase 2
120
California, District of Columbia, Kansas, Kentucky, Michigan, Missouri, Nebraska, Nevada
2022-06-01
Active, closed
STAND - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures
NCT04835428Vertebral Compression Fracture, Compression Fracture, Vertebral Compression
AgNovos Healthcare, LLC
Not applicable
408
Alabama, Arizona, Florida, Illinois, Kansas, Louisiana, Massachusetts, New York
2022-05-31
Active, closed
HEAL-IST IDE Trial
NCT05280093Inappropriate Sinus Tachycardia
AtriCure, Inc.
Not applicable
142
Arkansas, California, Connecticut, District of Columbia, Florida, Georgia, Idaho, Kansas
2022-05-31
Active, closed
Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)
NCT05186974Non-small Cell Lung Cancer
DrugsSacituzumab Govitecan·Paraplatin·Keytruda·Cisplatin
Gilead Sciences
Phase 2
193
Alaska, California, Colorado, District of Columbia, Florida, Georgia, Illinois, Kansas
2022-05-30
Active, closed
A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer
NCT05353257Limited-Stage Small Cell Lung Cancer
DrugsCarboplatin/cisplatin-etoposide·Slulimumab·Serplulimab
Shanghai Henlius Biotech
Phase 3
511
California, Colorado, Connecticut, Florida, Kansas, Louisiana, Minnesota, Nevada
2022-05-17
Active, closed
P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma
NCT04960579Multiple Myeloma
DrugsRimiducid·Methotrexate
Poseida Therapeutics, Inc.
Phase 1
275
Arizona, California, Georgia, Illinois, Iowa, Kansas, Maryland, Michigan
2022-05-05
Active, closed
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
NCT05269004Multiple Sclerosis
DrugOcrelizumab
Hoffmann-La Roche
Phase 3
1,300
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2022-05-03
Recruiting
Cephea Early Feasibility Study
NCT05061004Mitral Regurgitation
Abbott Medical Devices
Not applicable
90
Arizona, California, Georgia, Illinois, Kansas, Michigan, Minnesota, New York
2022-04-28
Active, closed
US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus
NCT05232838Hydrocephalus, Normal Pressure, Hydrocephalus
CereVasc Inc
Not applicable
50
Connecticut, Florida, Kansas, Kentucky, Massachusetts, New York, Rhode Island, Virginia
2022-04-20
Active, closed
Multi-Center Study of ManNAc for GNE Myopathy
NCT04231266GNE Myopathy
Leadiant Biosciences, Inc.
Phase 2
54
California, Iowa, Kansas, Maryland, Massachusetts, Missouri, New York, Ohio
2022-04-05
Active, closed
Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations
NCT05256290Non-Small Cell Lung Cancer, Advanced Non-Small Cell Squamous Lung Cancer, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Lung Cancer
Black Diamond Therapeutics, Inc.
Phase 1/2
200
Alabama, Arizona, California, District of Columbia, Florida, Hawaii, Illinois, Kansas
2022-03-31
Active, closed
Olorofim Aspergillus Infection Study
NCT05101187Invasive Aspergillosis
DrugAmbisome
F2G Biotech GmbH
Phase 3
225
Alabama, California, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2022-03-31
Recruiting
4D-710 in Adult Patients With Cystic Fibrosis
NCT05248230Cystic Fibrosis Lung
4D Molecular Therapeutics
Phase 2
30
Alabama, Arizona, California, Colorado, Florida, Illinois, Kansas, Maryland
2022-03-29
Active, closed
Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
NCT05317416Multiple Myeloma
DrugsElranatamab·Lenalidomide
Pfizer
Phase 3
854
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Kansas, Michigan
2022-03-25
Recruiting
GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC
NCT04864054Hepatocellular Carcinoma, Liver Cancer, Adult, Liver Neoplasm, Metastatic Liver Cancer
Eureka Therapeutics Inc.
Phase 1/2
60
California, Kansas, New York, Oregon, Texas, Washington
2022-03-11
Active, closed
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
NCT05100862Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
DrugsRuxience·Truxima·Zanubrutinib·Obinutuzumab
BeOne Medicines
Phase 3
799
California, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky
2022-03-10
Recruiting
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
NCT05201781Multiple Myeloma
DrugCilta-cel
Janssen Research & Development, LLC
Phase 4
295
Arizona, California, Florida, Georgia, Illinois, Indiana, Kansas, Massachusetts
2022-03-09
Active, closed
INTIBIA Pivotal Study
NCT05250908Urinary Incontinence, Urge, Urinary Bladder, Overactive, Urinary Bladder Diseases, Urologic Diseases
Coloplast A/S
Not applicable
208
California, District of Columbia, Florida, Georgia, Idaho, Kansas, Massachusetts, Michigan
2022-03-07
Recruiting
Inappropriate Sinus Tachycardia Registry
NCT05107635Inappropriate Sinus Tachycardia, Postural Tachycardia Syndrome
AtriCure, Inc.
Observational
500
California, Florida, Kansas, Maryland, Ohio, Texas, Utah, Washington
2022-03-01
Active, closed
A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer
NCT05243550Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
UroGen Pharma Ltd.
Phase 3
240
Arizona, California, Kansas, Maryland, Missouri, New Jersey, New York, Tennessee
2022-03-01
Active, closed
P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors
NCT05239143Breast Cancer, Ovarian Cancer, Non Small Cell Lung Cancer, Colorectal Cancer
DrugRimiducid
Poseida Therapeutics, Inc.
Phase 1
180
California, Colorado, Iowa, Kansas, Maryland, Massachusetts, Nebraska, New York
2022-02-15
Active, closed
A Gene Therapy Study of BMN 331 in Subjects With Hereditary Angioedema
NCT05121376Hereditary Angioedema, HAE
BioMarin Pharmaceutical
Phase 1/2
44
Alabama, Arizona, California, Colorado, Kansas, Maryland, Mississippi, Missouri
2022-02-15
Recruiting
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
NCT06378632Heart Failure
Cordio Medical
Observational
500
Alabama, California, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana
2022-02-11
Active, closed
Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older
NCT05304351Herpes Zoster, Shingles
DrugShingrix
Curevo Inc
Phase 2
1,516
Arizona, Florida, Illinois, Kansas, Kentucky, Nevada, Oklahoma, Tennessee
2022-02-02
Active, closed
Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer
NCT04905069Prostate Cancer
Boston Scientific Corporation
Not applicable
500
Florida, Kansas, Michigan, New Jersey, Pennsylvania, South Carolina
2021-12-21
By invitation
Long-Term Follow-Up Study After Gene-Modified Cell Treatment in Kite Studies
NCT05041309Solid and Hematological Malignancies, Autoimmune Diseases
DrugsKITE-197·SPRX002·KITE-753·Tecartus
Kite, A Gilead Company
Observational
1,500
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Iowa, Kansas
2021-12-15
Active, closed
CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer
NCT05210283Colorectal Cancer
Exact Sciences Corporation
Observational
1,017
California, Florida, Illinois, Iowa, Kansas, Maryland, Minnesota, Missouri
2021-12-15
Active, closed
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2)
NCT05156281Relapsing Multiple Sclerosis
DrugsTeriflunomide·Remibrutinib
Novartis Pharmaceuticals
Phase 3
1,007
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Indiana, Kansas
2021-12-13
Active, closed
NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies
NCT05023486Advanced or Metastatic Solid Tumor Malignancies
DrugPrilukae
Novita Pharmaceuticals, Inc.
Phase 1/2
121
Arizona, Arkansas, California, Connecticut, Florida, Indiana, Kansas, Michigan
2021-12-07
Active, closed
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)
NCT05130450Familial Chylomicronemia Syndrome
DrugOlezarsen
Ionis Pharmaceuticals, Inc.
Phase 3
60
California, Florida, Illinois, Kansas, New York, Pennsylvania
2021-11-18
Active, closed
Study of Sacituzumab Govitecan (SG) Versus Docetaxel in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
NCT05089734Non-Small Cell Lung Cancer
DrugsSacituzumab Govitecan·Docetaxel
Gilead Sciences
Phase 3
603
Alaska, Arizona, California, Colorado, Florida, Illinois, Iowa, Kansas
2021-11-17
Active, closed
Clinical Trial of MED HF10™ Spinal Cord Stimulation for the Treatment of Chronic Pain
NCT06897280Chronic, Intractable Back Pain and/or Leg Pain
Nevro Corp
Phase 4
25
Kansas
2021-11-16
Recruiting
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
NCT05065216Acute Stroke, Ischemic Stroke, Stroke
DiaMedica Therapeutics Inc
Phase 2/3
728
Alabama, California, Florida, Georgia, Illinois, Kansas, Louisiana, Massachusetts
2021-11-07
Active, closed
Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain
NCT04809376Osteoarthritis, Knee
DrugPentosan Polysulfate Sodium
Paradigm Biopharmaceuticals USA (INC)
Phase 2/3
602
Arizona, California, Florida, Illinois, Kansas, Louisiana, Nevada, South Carolina
2021-10-19
Active, closed
Study of Vimseltinib for Tenosynovial Giant Cell Tumor
NCT05059262Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath, Tenosynovial Giant Cell Tumor, Diffuse
DrugVimseltinib
Deciphera Pharmaceuticals, LLC
Phase 3
123
California, Colorado, Kansas, Massachusetts, Minnesota, New York, North Carolina, Ohio
2021-10-14
By invitation
SPI-1005 Treatment in Moderate COVID-19 Patients
NCT04484025Covid19, Corona Virus Infection, Coronavirus, Coronavirus Infection
DrugEbselen
Sound Pharmaceuticals, Incorporated
Phase 2
60
Connecticut, Idaho, Kansas, Missouri, North Carolina, Texas
2021-10-12
Active, closed
Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma
NCT04884035Lymphoma, B-Cell
DrugsGolcadomide·Iberdomide·Polatuzumab Vedotin·Prednisolone
Celgene
Phase 1
224
Alabama, Arizona, California, Florida, Georgia, Kansas, Minnesota, Nebraska
2021-09-15
Active, closed
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
NCT04961996Early Breast Cancer
DrugGiredestrant
Hoffmann-La Roche
Phase 3
4,170
Alabama, California, Colorado, Connecticut, Florida, Illinois, Kansas, Kentucky
2021-08-27
Active, closed
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.
NCT05024695Glaucoma
iSTAR Medical
Not applicable
975
Arizona, Arkansas, California, Colorado, Florida, Idaho, Illinois, Kansas
2021-08-19
Active, closed
US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair
NCT04852783Aneurysm, Intracranial
Cerus Endovascular, Inc.
Phase 4
250
Colorado, Florida, Illinois, Kansas, Massachusetts, New York, North Carolina, Pennsylvania
2021-08-06
Active, closed
Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases
NCT04640142Primary Immune Deficiency
Octapharma
Phase 3
50
California, Colorado, Florida, Illinois, Kansas, Kentucky, Maryland, Missouri
2021-08-04
Active, closed
EFS of the CardioMech MVRS
NCT04820764Mitral Regurgitation
CardioMech AS
Not applicable
35
California, Illinois, Kansas, Minnesota, New York, North Carolina, Ohio, Tennessee
2021-07-27
Active, closed
CYPRESS Efficacy and Safety Study Extension
NCT04947735Juvenile Myopia, Myopia
SightGlass Vision, Inc.
Not applicable
200
California, Florida, Kansas, Louisiana, Missouri, New York, South Dakota, Tennessee
2021-07-19
Recruiting
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
NCT04951622Myasthenia Gravis
DrugNipocalimab
Janssen Research & Development, LLC
Phase 3
199
Arizona, California, Colorado, Connecticut, Florida, Georgia, Kansas, Massachusetts
2021-07-15
Active, closed
FT819 in Subjects With B-cell Malignancies
NCT04629729Lymphoma, B-Cell, Chronic Lymphocytic Leukemia, Precursor B-Cell Acute Lymphoblastic Leukemia
DrugsFT819·Fludara·Aldesleukin·Bendamustine
Fate Therapeutics
Phase 1
54
Alabama, Arizona, California, Florida, Iowa, Kansas, Kentucky, Minnesota
2021-07-12
Active, closed
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
NCT05044819Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
DrugCannabidiol
Jazz Pharmaceuticals
Phase 4
154
Arkansas, California, Florida, Georgia, Kansas, Kentucky, Maryland, Massachusetts
2021-07-07
Recruiting
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261Pulmonary Embolism
Penumbra Inc.
Observational
1,500
California, Delaware, District of Columbia, Florida, Georgia, Illinois, Kansas, Louisiana
2021-06-25
Active, closed
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients
NCT04651634Head and Neck Squamous Cell Carcinoma, Oral Mucositis
DrugCCRT
MitoImmune Therapeutics
Phase 2
60
Arizona, California, Kansas, New York, North Carolina, Ohio
2021-06-21
Recruiting
A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
NCT04729114Prostate Cancer, Metastatic Castration Resistant Prostate Cancer, Metastatic Castration-sensitive Prostate Cancer
DrugsPRL-02·Enzalutamide·Prednisone·Dexamethasone
Astellas Pharma Global Development, Inc.
Phase 1
174
Arizona, California, Florida, Indiana, Kansas, Maryland, Nebraska, New Jersey
2021-06-14
Active, closed
Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients
NCT04736121Unresectable Hepatocellular Carcinoma, BCLC Stage A Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma
Sirtex Medical
Not applicable
100
California, Florida, Georgia, Kansas, Massachusetts, New York, North Carolina, Ohio
2021-05-28
Active, closed
Molecular Assessment and Profiling of Liver Transplant Recipients
NCT04793360Liver Transplantation, Biomarkers
CareDx
Observational
1,500
California, District of Columbia, Florida, Georgia, Kansas, Louisiana, Maryland, Massachusetts
2021-05-26
Recruiting
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
NCT07218029Pulmonary Arterial Hypertension
DrugSotatercept
Merck Sharp & Dohme LLC
Phase 3
815
Arizona, California, Colorado, District of Columbia, Florida, Georgia, Kansas, Kentucky
2021-05-12
Active, closed
A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis (ISR)
NCT04647253In-Stent Restenosis
Boston Scientific Corporation
Phase 3
600
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas
2021-05-11
Active, closed
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients
NCT04824092Diffuse Large B-cell Lymphoma
DrugsTafasitamab·Vincristine·Doxorubicin·Prednisone
Incyte Corporation
Phase 3
899
Alabama, California, Colorado, Florida, Hawaii, Kansas, Kentucky, Maryland
2021-05-11
Active, closed
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
NCT04777331Parkinsons Disease
DrugPrasinezumab
Hoffmann-La Roche
Phase 2
586
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Kansas
2021-05-05
Recruiting
Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh
NCT04779918Hernia, Ventral, Hernia, Inguinal
Tela Bio Inc
Not applicable
160
Alabama, Colorado, Florida, Kansas, Kentucky, Michigan, New York, Texas
2021-04-29
Recruiting
A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
NCT04752774Spasticity
DrugsDysport·Corabotase
Ipsen
Phase 1/2
240
California, Kansas, Michigan, Pennsylvania, Texas
2021-04-29
Active, closed
TRISCEND II Pivotal Trial
NCT04482062Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases
Edwards Lifesciences
Not applicable
864
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2021-04-09
Active, closed
Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)
NCT04365374Brain Metastases
GT Medical Technologies, Inc.
Phase 3
230
Arizona, Arkansas, Florida, Georgia, Illinois, Indiana, Kansas, Kentucky
2021-04-06
Active, closed
Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)
NCT04816604Pulmonary Arterial Hypertension
DrugSeralutinib
Gossamer Bio USA, Inc.
Phase 2
74
California, Florida, Kansas, Kentucky, Massachusetts, Nebraska, New York, Ohio
2021-04-05
Active, closed
Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
NCT04586023Relapsing Multiple Sclerosis
DrugsFenebrutinib·Teriflunomide
Hoffmann-La Roche
Phase 3
751
Alabama, Arizona, California, District of Columbia, Florida, Indiana, Kansas, Massachusetts
2021-03-24
Recruiting
Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
NCT04686305Locally Advanced or Metastatic Non-Small Cell Lung Cancer
DrugsVolrustomig·Rilvegostomig·Trastuzumab deruxtecan·Durvalumab
AstraZeneca
Phase 1
304
California, Kansas, Maryland, Michigan, New York, Texas, Virginia, Washington
2021-03-09
Active, closed
Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation
NCT04685135Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer
DrugsAdagrasib·Taxotere·Docetaxel
Mirati Therapeutics Inc.
Phase 3
453
California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas, Kentucky
2021-02-23
Active, closed
Firehawk Rapamycin Target Eluting Coronary Stent North American Trial
NCT04562532Coronary Artery Disease
Shanghai MicroPort Medical (Group) Co., Ltd.
Not applicable
1,720
Alabama, Arizona, California, Connecticut, Florida, Georgia, Indiana, Kansas
2021-02-17
Active, closed
Immunogenicity, Safety, Reactogenicity and Persistence of an Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above
NCT04732871Respiratory Syncytial Virus Infections
GlaxoSmithKline
Phase 3
1,720
Alabama, Arizona, California, Florida, Indiana, Kansas, Minnesota, Missouri
2021-02-15
Active, closed
The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy
NCT04572633Liver Neoplasms, Hepatocellular Carcinoma, Liver Metastases
HistoSonics, Inc.
Not applicable
47
Florida, Illinois, Kansas, Michigan, Wisconsin
2021-01-27
Active, closed
A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma
NCT04657991Melanoma
DrugsBinimetinib·Encorafenib·Keytruda·Pembrolizumab
Pfizer
Phase 3
257
Florida, Kansas, Massachusetts, Ohio, Tennessee
2021-01-15
Active, closed
A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)
NCT04204616Prurigo Nodularis
DrugNemolizumab
Galderma R&D
Phase 3
500
Alabama, California, District of Columbia, Florida, Georgia, Illinois, Indiana, Kansas
2021-01-11
Active, closed
A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy
NCT04640623Urinary Bladder Neoplasms
DrugsTAR-200·Cetrelimab
Janssen Research & Development, LLC
Phase 2
220
Arizona, California, Colorado, Illinois, Indiana, Kansas, Michigan, New York
2020-12-18
Active, closed
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)
NCT04544436Multiple Sclerosis
DrugsOcrelizumab·Methylprednisolone
Hoffmann-La Roche
Phase 3
864
Alabama, Arizona, California, Colorado, Florida, Indiana, Kansas, Louisiana
2020-11-26
Active, closed
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine
NCT04616326Chronic Migraine
DrugGalcanezumab
Eli Lilly and Company
Phase 3
312
Alabama, Arizona, California, Colorado, Florida, Idaho, Illinois, Kansas
2020-11-25
Recruiting
ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)
NCT04561518Transthyretin-Mediated Amyloidosis, ATTR Amyloidosis
Alnylam Pharmaceuticals
Observational
1,500
California, Florida, Iowa, Kansas, Maryland, Massachusetts, New York, North Carolina
2020-11-23
Active, closed
Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy
NCT04281485Duchenne Muscular Dystrophy
Pfizer
Phase 3
114
Arkansas, California, Florida, Iowa, Kansas, North Carolina, Pennsylvania, Utah
2020-11-05
Active, closed
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis
NCT04544449Multiple Sclerosis, Primary Progressive
DrugsFenebrutinib·Ocrelizumab
Hoffmann-La Roche
Phase 3
985
Alabama, California, Colorado, Connecticut, District of Columbia, Florida, Indiana, Kansas
2020-10-26
Active, closed
Claudin18.2 CAR-T (CT041) in Patients With Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers
NCT04404595Gastric Cancer, Pancreatic Cancer
CARsgen Therapeutics Co., Ltd.
Phase 1/2
110
California, Florida, Kansas, Michigan, Minnesota, New York, Ohio, Texas
2020-10-23
Active, closed
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC
NCT04446117Metastatic Prostate Cancer, Prostate Adenocarcinoma
DrugsZytiga·Xtandi·Abiraterone·Abiraterone acetate
Exelixis
Phase 3
575
Arizona, California, Colorado, Connecticut, Florida, Georgia, Kansas, Kentucky
2020-10-19
Active, closed
Myasthenia Gravis Inebilizumab Trial
NCT04524273Myasthenia Gravis
DrugInebilizumab
Amgen
Phase 3
238
California, Connecticut, District of Columbia, Florida, Kansas, North Carolina, Ohio, Pennsylvania
2020-10-15
Active, closed
A Study of DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid Tumors
NCT04440735Advanced Solid Tumor, Non Small Cell Lung Cancer, Colorectal Cancer
DrugsDSP107·Atezolizumab
Kahr Medical
Phase 1/2
125
California, Colorado, Florida, Indiana, Kansas, Pennsylvania
2020-10-07
Active, closed
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
NCT04590963Squamous Cell Carcinoma of the Head and Neck
DrugsMonalizumab·Erbitux·Cetuximab
AstraZeneca
Phase 3
370
Arizona, Illinois, Kansas, Massachusetts, Michigan, Minnesota, Missouri, Nevada
2020-10-02
Active, closed
A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE)
NCT04093349Pompe Disease, Pompe Disease (Late-onset), Glycogen Storage Disease Type 2, Glycogen Storage Disease Type II
Spark Therapeutics, Inc.
Phase 1/2
4
Arizona, California, Georgia, Kansas, Minnesota, Oregon, Pennsylvania, Utah
2020-10-01
Active, closed
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
NCT04526665Primary Biliary Cirrhosis
DrugElafibranor
Ipsen
Phase 3
161
Arizona, California, Colorado, Connecticut, Florida, Georgia, Kansas, Massachusetts
2020-09-24
Active, closed
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves)
NCT04280718Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
DrugEfgartigimod PH20
argenx
Phase 2
229
Alabama, Arizona, California, Colorado, Florida, Iowa, Kansas, Kentucky
2020-09-18
Recruiting
ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies
NCT04412616Advanced EGFR Positive Solid Tumor
Changchun Intellicrown Pharmaceutical Co. LTD
Phase 1
60
California, Kansas, New York
2020-09-01
Active, closed
A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME)
NCT04469595Diabetic Macular Edema
DrugsEylea·Aflibercept
Alimera Sciences
Phase 4
300
Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas, Louisiana
2020-08-31
Recruiting
Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523Primary Open Angle Glaucoma
Alcon Research
Not applicable
545
California, Colorado, Iowa, Kansas, Maryland, Michigan, Minnesota, Missouri
2020-08-25
Active, closed
Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL
NCT04404283Diffuse Large B-cell Lymphoma
DrugsBrentuximab Vedotin·Lenalidomide·Rituximab
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
239
Alabama, California, Florida, Kansas, Maryland, Michigan, Missouri, Ohio
2020-08-20
Active, closed
A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies
NCT04227847Myelodysplastic Syndrome, Acute Myeloid Leukemia
DrugsVenclexta·Azacitidine·Venetoclax
Seagen, a wholly owned subsidiary of Pfizer
Phase 1
170
Alabama, California, Colorado, Kansas, Kentucky, Massachusetts, Michigan, Missouri
2020-08-07
Active, closed
Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465)
NCT04509700B-Cell Malignancies
DrugsItacitinib·Parsaclisib·Ibrutinib·Ruxolitinib
Incyte Corporation
Phase 2
112
Alabama, Arizona, California, Colorado, Illinois, Kansas, Maryland, Massachusetts
2020-08-03
Active, closed
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
NCT04494425Advanced or Metastatic Breast Cancer
DrugsTrastuzumab deruxtecan·Nab-paclitaxel·Capecitabine·Paclitaxel
AstraZeneca
Phase 3
866
Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Kansas, Kentucky
2020-07-24
Active, closed
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)
NCT04245839Lymphoma, Non-Hodgkin
DrugsBreyanzi·Fludarabine·Cyclophosphamide
Celgene
Phase 2
276
California, Colorado, Connecticut, Illinois, Iowa, Kansas, Maryland, Massachusetts
2020-07-14
Active, closed
Evaluation of Safety and Effectiveness of Stryker Surpass Evolve™ Flow Diverter System
NCT04195568Aneurysm, Intracranial
Stryker Neurovascular
Not applicable
248
Arizona, California, Florida, Illinois, Indiana, Iowa, Kansas, Kentucky
2020-07-07
Active, closed
SELUTION SLR™ 014 In-stent Restenosis
NCT04280029Coronary Restenosis
M.A. Med Alliance S.A.
Not applicable
418
California, Colorado, District of Columbia, Florida, Georgia, Indiana, Kansas, Maryland
2020-07-06
Active, closed
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
NCT04181827Multiple Myeloma
DrugsCilta-cel·Pomalidomide·Bortezomib·Daratumumab
Janssen Research & Development, LLC
Phase 3
419
Alabama, Arizona, California, Colorado, Connecticut, Florida, Iowa, Kansas
2020-06-12
Recruiting
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
NCT04389632Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, HER2 Negative Breast Neoplasms, Esophageal Squamous Cell Carcinoma
DrugsSigvotatug vedotin·Keytruda·Cisplatin·Carboplatin
Seagen, a wholly owned subsidiary of Pfizer
Phase 1
1,006
Alaska, Arkansas, California, Florida, Illinois, Indiana, Kansas, Massachusetts
2020-06-08
Active, closed
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
NCT04404660Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
DrugAUTO1
Autolus Limited
Phase 1/2
153
California, Colorado, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2020-06-03
Active, closed
Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)
NCT04296903Adolescent Idiopathic Scoliosis
Apifix
Not applicable
201
California, Florida, Georgia, Indiana, Kansas, Minnesota, Mississippi, Missouri
2020-05-31
Active, closed
A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors
NCT04396821Advanced Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, Pancreatic Cancer
DrugsTST001·MFOLFOX6·Albumin-Bound Paclitaxel·Opdivo
Transcenta Therapeutics (Hangzhou) Co., Ltd.
Phase 1/2
150
Arizona, Connecticut, Florida, Georgia, Kansas, Missouri, New York, North Carolina
2020-05-28
Active, closed
Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
NCT04246047Multiple Myeloma
DrugsBelantamab mafodotin·Bortezomib·Daratumumab·Dexamethasone
GlaxoSmithKline
Phase 3
494
Arizona, Colorado, Kansas, Ohio, Texas
2020-05-07
Active, closed
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer
NCT04305496Locally Advanced (Inoperable) or Metastatic Breast Cancer
DrugsCapivasertib·Fulvestrant
AstraZeneca
Phase 3
818
Arizona, California, Florida, Kansas, Maryland, Massachusetts, Minnesota, Missouri
2020-04-16
Active, closed
Study of HPN217 in Participants With Relapsed/Refractory Multiple Myeloma MK-4002 (MK-4002-001)
NCT04184050Multiple Myeloma in Relapse, Multiple Myeloma, Multiple Myeloma of Bone, Multiple Myeloma With Failed Remission
Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 1
100
Arizona, California, Kansas, New York, Oregon, Washington
2020-04-13
Recruiting
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body
NCT04142437Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
DrugLarotrectinib
Bayer
Observational
150
Arizona, California, Colorado, Connecticut, Florida, Indiana, Kansas, Maine
2020-04-03
Active, closed
Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies
NCT04277637Mature B-Cell Malignancies
DrugsSonrotoclax·Zanubrutinib·Obinutuzumab
BeOne Medicines
Phase 1
437
California, Illinois, Kansas, Massachusetts, Minnesota, Nebraska, New Jersey, New York
2020-03-24
Active, closed
A Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)
NCT04225117Locally Advanced or Metastatic Malignant Solid Tumors
DrugsEnfortumab Vedotin·Keytruda·Pembrolizumab
Astellas Pharma Global Development, Inc.
Phase 2
329
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2020-03-10
Recruiting
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
NCT04221542Prostate Cancer
DrugsXaluritamig·Abiraterone·Enzalutamide
Amgen
Phase 1
479
California, Colorado, Connecticut, Georgia, Indiana, Kansas, Louisiana, Missouri
2020-03-04
Active, closed
Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)
NCT04199689Papillomavirus Infections
DrugNonavalent HPV vaccine
Merck Sharp & Dohme LLC
Phase 3
6,033
California, Florida, Georgia, Idaho, Kansas, Kentucky, Missouri, Nevada
2020-02-27
By invitation
Global Utilization And Registry Database for Improved heArt preservatioN
NCT04141605Heart Diseases, Heart Failure, Heart Defects, Congenital
Paragonix Technologies
Observational
3,000
California, District of Columbia, Florida, Indiana, Kansas, Massachusetts, Michigan, New York
2020-02-14
Active, closed
A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)
NCT04192591Lumbar Spinal Stenosis
Boston Scientific Corporation
Not applicable
166
California, Florida, Georgia, Idaho, Illinois, Kansas, Massachusetts, Michigan
2020-01-30
Active, closed
A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described
NCT04122976Prostate Cancer
DrugDarolutamide
Bayer
Observational
805
Alabama, Arizona, California, Colorado, Florida, Illinois, Indiana, Kansas
2020-01-30
Active, closed
MitraClip EXPAND G4 Study
NCT04177394Mitral Valve Regurgitation, Mitral Regurgitation
Abbott Medical Devices
Observational
1,164
Alabama, Arkansas, California, Connecticut, Florida, Illinois, Kansas, Minnesota
2020-01-17
Active, closed
Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple Myeloma
NCT04091126Multiple Myeloma
DrugsBelantamab mafodotin·Bortezomib·Lenalidomide·Dexamethasone
GlaxoSmithKline
Phase 1
118
Kansas, North Carolina, Wisconsin
2019-12-18
Active, closed
Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)
NCT04232696Urinary Urgency Incontinence
Neuspera Medical, Inc.
Not applicable
331
California, Florida, Georgia, Illinois, Indiana, Kansas, Kentucky, Louisiana
2019-12-13
Active, closed
Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)
NCT04146051Myasthenia Gravis, Generalized
DrugDescartes-08
Cartesian Therapeutics
Phase 2
30
California, Colorado, Florida, Georgia, Kansas, New York, North Carolina, Oregon
2019-12-04
Recruiting
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847Movement Disorders, Parkinson Disease, Essential Tremor, Tremor
Abbott Medical Devices
Observational
1,000
Arizona, California, Colorado, Florida, Illinois, Indiana, Kansas, Kentucky
2019-11-26
Recruiting
Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02
NCT04167696Acute Myeloid Leukemia, Myelodysplastic Syndrome
DrugsEndoxan·Fludara·Fludarabine·Cyclophosphamide
Celyad Oncology SA
Phase 1
27
Florida, Kansas
2019-11-25
Active, closed
Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
NCT04013685Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Myelodysplastic Syndromes, Acute Leukemia
DrugOrca-T
Orca Biosystems, Inc.
Phase 1
155
California, Colorado, Florida, Georgia, Illinois, Kansas, Massachusetts, Michigan
2019-11-21
Active, closed
An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis
NCT04130997Relapsing Multiple Sclerosis (RMS)
DrugUblituximab
TG Therapeutics, Inc.
Phase 3
1,100
California, Colorado, Florida, Illinois, Kansas, Michigan, Nevada, New Jersey
2019-11-18
Active, closed
A Study of Tyrosine Kinase Inhibitor Orelabrutinib (ICP-022) in Patients With r/r B-Cell Malignancies
NCT04014205Part 1：r/r B-cell Malignancies, Part 2：B-cell Malignancies
DrugOrelabrutinib
Beijing InnoCare Pharma Tech Co., Ltd.
Phase 1/2
81
Arizona, California, Florida, Illinois, Indiana, Kansas, Louisiana, Maryland
2019-11-18
Active, closed
A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma
NCT04133636Multiple Myeloma
DrugsCilta-cel·Bortezomib·Daratumumab·Lenalidomide
Janssen Research & Development, LLC
Phase 2
208
California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas
2019-11-07
Active, closed
Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics
NCT03953300Asthma
DrugBenralizumab
AstraZeneca
Phase 4
75
Alabama, California, Florida, Georgia, Indiana, Iowa, Kansas, Michigan
2019-10-08
Active, closed
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04033445Ulcerative Colitis
DrugGuselkumab
Janssen Research & Development, LLC
Phase 2/3
1,064
California, Colorado, Florida, Georgia, Illinois, Kansas, Kentucky, Massachusetts
2019-09-26
Recruiting
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
NCT03887715Treatment Resistant Depression
LivaNova
Not applicable
6,800
Alabama, California, Florida, Georgia, Idaho, Illinois, Indiana, Kansas
2019-09-26
Active, closed
Portico Next Generation Approval Study
NCT04011722Symptomatic Severe Aortic Stenosis
Abbott Medical Devices
Not applicable
333
California, District of Columbia, Illinois, Indiana, Kansas, Michigan, Minnesota, New Jersey
2019-09-17
Active, closed
Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia
NCT04119050Warm Autoimmune Hemolytic Anemia
DrugNipocalimab
Janssen Research & Development, LLC
Phase 2/3
118
California, Colorado, Florida, Illinois, Kansas, Louisiana, Michigan, Missouri
2019-08-15
Active, closed
A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis
NCT04035005Multiple Sclerosis, Primary Progressive
DrugOcrelizumab
Hoffmann-La Roche
Phase 3
1,013
District of Columbia, Florida, Kansas, Ohio, Pennsylvania
2019-08-12
Active, closed
Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil
NCT03992755Primary Pulmonary Hypertension
DrugTreprostinil
Liquidia Technologies, Inc.
Phase 3
92
Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas, Louisiana
2019-07-18
Active, closed
Citadel Embolization Device Study
NCT04057352Unruptured Wide-neck Aneurysms
Stryker Neurovascular
Not applicable
150
California, Colorado, Florida, Illinois, Indiana, Kansas, Kentucky, Massachusetts
2019-07-18
Active, closed
A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2)
NCT04035486Non-Small Cell Lung Cancer
DrugsPemetrexed/Cisplatin·Pemetrexed/Carboplatin·Osimertinib
AstraZeneca
Phase 3
587
California, Florida, Kansas, Kentucky, Massachusetts, Nevada, New York, Ohio
2019-07-02
Active, closed
Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL
NCT03960840Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Diffuse Large B-cell Lymphoma, Acute Lymphoblastic Leukemia
DrugIbrutinib
Novartis Pharmaceuticals
Phase 1/2
217
California, Florida, Illinois, Kansas, Massachusetts, Pennsylvania, Tennessee, Texas
2019-06-26
Active, closed
Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC
NCT03997123Triple Negative Breast Neoplasms
DrugsCapivasertib·Paclitaxel
AstraZeneca
Phase 3
923
California, Florida, Illinois, Kansas, Maryland, Michigan, New York, Ohio
2019-06-25
Active, closed
Early Feasibility Study for the Foldax Tria Aortic Heart Valve
NCT03851068Aortic Valve Disease, Aortic Valve Stenosis
Foldax, Inc
Not applicable
40
Indiana, Kansas, Michigan, Ohio
2019-06-18
Recruiting
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
NCT03808922Lower Respiratory Tract Infection, Parainfluenza, Immunocompromised, COVID-19
Ansun Biopharma, Inc.
Phase 3
274
California, Illinois, Iowa, Kansas, Maryland, Massachusetts, Minnesota, Missouri
2019-05-23
Active, closed
A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)
NCT03930953Lymphoma, Non-Hodgkin
DrugsValemetostat·Tafasitamab·Golcadomide·Obinutuzumab
Celgene
Phase 1/2
438
Arizona, Florida, Kansas, Minnesota, Missouri, New Jersey, Texas
2019-05-20
Active, closed
Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment
NCT03847428Hepatocellular Carcinoma
DrugsAvastin·Durvalumab·Bevacizumab
AstraZeneca
Phase 3
908
Alabama, Arizona, California, District of Columbia, Florida, Hawaii, Illinois, Kansas
2019-04-29
Active, closed
Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
NCT03104517Stress Urinary Incontinence
DrugIltamiocel
Cook MyoSite
Phase 3
96
Arizona, California, District of Columbia, Kansas, Michigan, New Mexico, New York, North Carolina
2019-04-23
Active, closed
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)
NCT03875235Biliary Tract Neoplasms
DrugDurvalumab
AstraZeneca
Phase 3
810
California, District of Columbia, Florida, Kansas, Kentucky, Massachusetts, Missouri, North Carolina
2019-04-16
Active, closed
(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis
NCT03731260Indolent Systemic Mastocytosis
DrugAvapritinib
Blueprint Medicines Corporation
Phase 2
251
Alabama, Arizona, California, Florida, Georgia, Illinois, Kansas, Massachusetts
2019-04-16
Recruiting
A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
NCT03802695Acute Myeloid Leukemia, Myelodysplastic Syndromes, Mixed Phenotype Acute Leukemia, Acute Lymphoblastic Leukemia
Orca Biosystems, Inc.
Phase 1
300
California, Florida, Georgia, Kansas, New Jersey, New York, Ohio, Texas
2019-04-08
Active, closed
A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors
NCT03845166Neoplasm Malignant, Renal Cell Carcinoma, Hormone Receptor Positive Breast Carcinoma, Metastatic Castration-resistant Prostate Cancer
DrugsZanzalintinib·Avelumab·Tecentriq·Atezolizumab
Exelixis
Phase 1
325
California, Florida, Georgia, Iowa, Kansas, Maine, Maryland, Massachusetts
2019-03-20
Active, closed
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
NCT03836261Chronic Lymphocytic Leukemia
DrugsVenclyxto·Acalabrutinib·Venclexta·Obinutuzumab
Acerta Pharma BV
Phase 3
984
California, Indiana, Kansas, Kentucky, Louisiana, Maryland, Massachusetts, New York
2019-02-25
Recruiting
ProACT Post-Approval Study
NCT03767595Stress Urinary Incontinence
Uromedica
Not applicable
145
Colorado, Florida, Georgia, Kansas, Michigan, Minnesota
2019-02-19
Active, closed
Clinical Trial Multi-analyte Blood Test
NCT03694600Liver Cirrhosis
Helio Genomics
Observational
1,900
Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas, Kentucky
2019-02-04
Recruiting
A Trial to Evaluate Safety, Tolerability, and Preliminary Efficacy of Misetionamide (GP-2250) as Monotherapy or in Combination With Gemcitabine
NCT03854110Ovarian Cancer
DrugGemcitabine
Persevere Therapeutics Inc.
Phase 1
80
Illinois, Kansas, Massachusetts, Pennsylvania
2019-01-14
Active, closed
9-ING-41 in Patients With Advanced Cancers
NCT03678883Cancer, Pancreatic Cancer, Sarcoma, Renal Cancer
DrugsCCNU·Lomustine·Abraxane·Adriamycin
Actuate Therapeutics Inc.
Phase 2
350
Arizona, California, Delaware, District of Columbia, Florida, Illinois, Iowa, Kansas
2019-01-04
Active, closed
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)
NCT03711032High-risk Non-muscle Invasive Bladder Cancer
DrugsKeytruda·Pembrolizumab
Merck Sharp & Dohme LLC
Phase 3
1,397
Alaska, Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas
2018-12-24
Active, closed
A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC
NCT03661866Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo
Target PharmaSolutions, Inc.
Observational
15,000
Arizona, Arkansas, California, District of Columbia, Florida, Illinois, Indiana, Kansas
2018-12-21
Active, closed
Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
NCT03765918Head and Neck Neoplasms
DrugsKeytruda·Cisplatin·Pembrolizumab
Merck Sharp & Dohme LLC
Phase 3
714
California, Colorado, District of Columbia, Florida, Idaho, Illinois, Kansas, Kentucky
2018-12-17
Active, closed
A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer
NCT03800134Non-Small Cell Lung Cancer
DrugsDurvalumab·Pemetrexed·Gemcitabine·Paclitaxel
AstraZeneca
Phase 3
825
Arizona, California, Colorado, Florida, Illinois, Kansas, Kentucky, Maryland
2018-12-06
Active, closed
A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).
NCT03653507Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
DrugsZolbetuximab·Capecitabine·Oxaliplatin
Astellas Pharma Global Development, Inc.
Phase 3
507
California, Kansas, Louisiana, New Mexico, New York, South Carolina, Texas, Utah
2018-11-28
Active, closed
Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC
NCT03732677Muscle Invasive Bladder Cancer
DrugsDurvalumab·Gemcitabine·Cisplatin
AstraZeneca
Phase 3
1,063
Alabama, California, Connecticut, Illinois, Iowa, Kansas, Kentucky, Louisiana
2018-11-16
Active, closed
Destination Therapy Post Approval Study
NCT03681210Chronic Heart Failure
Medtronic Cardiac Rhythm and Heart Failure
Observational
300
Arkansas, California, Colorado, Florida, Illinois, Indiana, Kansas, Kentucky
2018-10-31
Active, closed
Long-Term Follow-Up Study for Subjects Treated With P-BCMA-101
NCT03741127Multiple Myeloma
Poseida Therapeutics, Inc.
Phase 1
100
California, Colorado, Illinois, Kansas, Maryland, Michigan, Pennsylvania, Tennessee
2018-10-29
Active, closed
A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia
NCT03589326Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
DrugsPonatinib·Imatinib·Cytarabine·Vincristine
Takeda
Phase 3
245
Alabama, California, Georgia, Indiana, Kansas, Maryland, New Jersey, New York
2018-10-04
Active, closed
Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer
NCT03682068Unresectable Locally Advanced Urothelial Cancer, Metastatic Urothelial Cancer
DrugsTremelimumab·Durvalumab·Gemcitabine·Cisplatin
AstraZeneca
Phase 3
1,246
Alabama, California, Connecticut, District of Columbia, Florida, Illinois, Indiana, Kansas
2018-09-27
Active, closed
ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis
NCT03517436Aortic Valve Stenosis
Edwards Lifesciences
Not applicable
101
California, Colorado, District of Columbia, Florida, Georgia, Indiana, Kansas, Massachusetts
2018-09-18
Active, closed
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
NCT03398135Ulcerative Colitis (UC)
DrugsSkyrizi·Risankizumab
AbbVie
Phase 3
1,242
California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Kansas
2018-08-28
Recruiting
Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
NCT03523416Heart Failure
Edwards Lifesciences
Not applicable
90
California, Colorado, Florida, Indiana, Kansas, Minnesota, New Jersey, New York
2018-07-31
Active, closed
Control of Myopia Using Novel Spectacle Lens Designs
NCT03623074Juvenile Myopia
SightGlass Vision, Inc.
Not applicable
266
California, Florida, Kansas, Louisiana, Missouri, New York, South Dakota, Tennessee
2018-07-16
Active, closed
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors
NCT03485209Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Exocrine Pancreatic Cancer, Carcinoma, Squamous Cell of Head and Neck
DrugsTisotumab Vedotin·Tivdak·Keytruda·Cisplatin
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
350
California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Kansas
2018-06-25
Active, closed
A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation
NCT03383458Hepatocellular Carcinoma, Liver Cancer
DrugsOpdivo·Nivolumab
Bristol-Myers Squibb
Phase 3
545
Alabama, Arizona, California, Colorado, Florida, Georgia, Kansas, Louisiana
2018-04-18
Recruiting
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
NCT03460977Metastatic Castration Resistant Prostate Cancer (mCRPC), Small Cell Lung Cancer (SCLC), Follicular Lymphoma (FL)
DrugsMevrometostat·Xtandi·Itraconazole·Enzalutamide
Pfizer
Phase 1
453
Arizona, California, Connecticut, Kansas, Kentucky, Maryland, Massachusetts, Nebraska
2018-04-17
Active, closed
Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients
NCT02922036Heart Failure
EBR Systems, Inc.
Not applicable
300
Alabama, California, Florida, Georgia, Illinois, Indiana, Iowa, Kansas
2018-01-17
Active, closed
Dose Finding Study to Determine if BEZ235 Alone or in Combination With RAD001 Decreases the Incidence of Respiratory Tract Infections in the Elderly
NCT03373903Respiratory Tract Infections
DrugsDactolisib·Everolimus
Restorbio Inc.
Phase 2
652
Kansas
2017-11-15
Active, closed
Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
NCT03298451Hepatocellular Carcinoma
DrugsSorafenib·Tremelimumab·Durvalumab
AstraZeneca
Phase 3
1,324
California, District of Columbia, Florida, Kansas, Maryland, Michigan, Minnesota, New York
2017-10-11
Active, closed
Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom
NCT02952508Waldenstrom Macroglobulinemia, Multiple Myeloma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugCLR 131
Cellectar Biosciences, Inc.
Phase 2
120
California, District of Columbia, Florida, Georgia, Illinois, Kansas, Louisiana, Maryland
2017-07-26
Active, closed
A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions
NCT03118505Multi-Level Degenerative Lumbosacral Spinal Conditions
Medtronic Spinal and Biologics
Not applicable
100
California, Colorado, Florida, Georgia, Indiana, Kansas, Michigan, New York
2017-06-29
Active, closed
A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's Disease
NCT03100149Parkinson's Disease
DrugPrasinezumab
Hoffmann-La Roche
Phase 2
316
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Kansas
2017-06-27
Active, closed
Evaluation of the Personal KinetiGraph™ (PKG™) to Improve Insight Into Parkinson's Disease Status
NCT03741920Parkinson Disease
Global Kinetics Corporation
Not applicable
231
California, Florida, Kansas, Maryland, Michigan, New York, Texas
2017-05-17
Active, closed
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL
NCT02972840Lymphoma, Mantle Cell
DrugsAcalabrutinib·Bendamustine·Rituximab
Acerta Pharma BV
Phase 3
635
Arizona, California, Connecticut, District of Columbia, Florida, Georgia, Kansas, Kentucky
2017-04-05
Active, closed
Durvalumab ± Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (CASPIAN)
NCT03043872Small Cell Lung Carcinoma Extensive Disease
DrugsTremelimumab·Etoposide·Durvalumab·Cisplatin
AstraZeneca
Phase 3
987
Alabama, Arizona, Arkansas, California, Connecticut, Georgia, Indiana, Kansas
2017-03-27
Active, closed
A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy
NCT02993523Acute Myeloid Leukemia (AML)
DrugsAzacitidine·Venetoclax
AbbVie
Phase 3
443
California, Georgia, Illinois, Indiana, Kansas, Kentucky, Maine, Maryland
2017-02-02
Active, closed
A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD)
NCT02951598Alzheimer Disease, Mild Cognitive Impairment
Eli Lilly and Company
Observational
1,400
California, Colorado, Connecticut, Florida, Georgia, Indiana, Kansas, Kentucky
2016-10-29
Active, closed
A Study to Determine Dose, Safety, Tolerability and Efficacy of CC-220 Monotherapy, and in Combination With Other Treatments in Subjects With Multiple Myeloma
NCT02773030Multiple Myeloma
DrugsIberdomide·Darzalex·Velcade·Carfilzomib
Celgene
Phase 1/2
466
Arizona, Arkansas, Georgia, Illinois, Kansas, Maryland, Massachusetts, Michigan
2016-10-14
Active, closed
Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell Carcinoma
NCT02811861Renal Cell Carcinoma
DrugsSunitinib·Everolimus·Lenvatinib·Pembrolizumab
Eisai Inc.
Phase 3
1,069
California, Florida, Illinois, Kansas, Louisiana, Maryland, Massachusetts, Michigan
2016-10-13
Recruiting
MEASuRE: Metreleptin Effectiveness And Safety Registry
NCT02325674Generalised Lipodystrophy, Partial Lipodystrophy
DrugMetreleptin
Chiesi Farmaceutici S.p.A.
Observational
100
Alabama, California, Georgia, Illinois, Kansas, Louisiana, Maryland, Michigan
2016-10-11
Active, closed
Study of Gene Modified Donor T Cell Infusion in Patients With Recurrent Disease After Allogeneic Transplant
NCT02477878Leukemia, Myelodysplastic Syndromes, Lymphoma, Multiple Myeloma
DrugRimiducid
Bellicum Pharmaceuticals
Phase 1
10
Georgia, Kansas, New York, Oregon, Texas
2016-07
Active, closed
Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
NCT02665065Acute Myeloid Leukemia, Leukemia, Acute Myeloid, Myeloid Leukemia, Acute, Leukemia, Myeloid, Acute
Actinium Pharmaceuticals
Phase 3
153
Arizona, Connecticut, District of Columbia, Florida, Illinois, Iowa, Kansas, Minnesota
2016-06
Recruiting
Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
NCT02781883Acute Myeloid Leukemia (AML)
DrugsVentoclax·Decitabine
Bio-Path Holdings, Inc.
Phase 2
108
California, Georgia, Kansas, New Jersey, New York, Texas, West Virginia
2016-05
Active, closed
A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction
NCT02724371Breast Reconstruction, Revision Breast Reconstruction
Mentor Worldwide, LLC
Not applicable
400
Alabama, Arizona, California, Georgia, Indiana, Iowa, Kansas, Minnesota
2016-04-01
Recruiting
CAR-T Long Term Follow Up (LTFU) Study
NCT02445222Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
Novartis Pharmaceuticals
Phase 3
1,105
Arizona, California, Georgia, Illinois, Kansas, Massachusetts, Michigan, Minnesota
2015-11-02
Active, closed
Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Participants With High Risk Chronic Lymphocytic Leukemia (CLL)
NCT02477696Chronic Lymphocytic Leukemia
DrugsIbrutinib·Acalabrutinib
Acerta Pharma BV
Phase 3
533
Arizona, California, Florida, Georgia, Illinois, Kansas, Minnesota, Montana
2015-07-28
Active, closed
Acalabrutinib, Obinutuzumab and Chlorambucil in Treatment naïve CLL
NCT02475681Chronic Lymphocytic Leukemia
DrugsChlorambucil·Acalabrutinib·Obinutuzumab
Acerta Pharma BV
Phase 3
535
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Indiana, Kansas
2015-06-26
Active, closed
A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY)
NCT02411448Metastatic Non-Small Cell Lung Cancer
DrugsGefitinib·Erlotinib·Ramucirumab·Osimertinib
Eli Lilly and Company
Phase 3
545
California, Colorado, Hawaii, Kansas, New York, North Carolina, Pennsylvania
2015-05-06
Active, closed
Infusion of Apomorphine: Long-term Safety Study
NCT02339064Idiopathic Parkinson's Disease
MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals
Phase 3
99
Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas, Michigan
2015-02
Recruiting
Blue Light Cystoscopy With Cysview® Registry
NCT02660645Bladder Cancer
DrugHexvix
Photocure
Observational
4,400
Alabama, Arizona, California, District of Columbia, Georgia, Illinois, Indiana, Kansas
2014-04
Active, closed
A Long-term Extension Study of PCI-32765 (Ibrutinib)
NCT01804686Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma
DrugIbrutinib
Janssen Research & Development, LLC
Phase 3
539
California, Connecticut, Georgia, Illinois, Indiana, Kansas, Kentucky, Massachusetts
2013-09-09
Recruiting
RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
NCT01719055Pain
Boston Scientific Corporation
Observational
4,800
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2012-11-19
Active, closed
A Study of LY2784544 in Participants With Myeloproliferative Neoplasms
NCT01594723Neoplasms, Hematologic
Eli Lilly and Company
Phase 2
110
Arkansas, California, Connecticut, Florida, Illinois, Indiana, Kansas, Maryland
2012-05-22
Active, closed
Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
NCT01526681Peripheral Nerve Injuries
Axogen Corporation
Observational
3,126
Arizona, California, Colorado, District of Columbia, Florida, Georgia, Kansas, Kentucky
2008-11
Active, closed
PhII ICb With/Without Erbitux in MBC Pts
NCT00248287Metastatic Breast Cancer
DrugsErbitux·Irinotecan·Carboplatin
US Oncology Research
Phase 2
154
Alabama, Arizona, Colorado, Connecticut, Florida, Illinois, Indiana, Kansas
2005-07-28
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 6 October 2026. https://priyalifescience.com/clinical-trials-usa/state/kansas?page=2

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,118 studies in total at the last sync on 06 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 743 of those studies with a site in Kansas.

How many clinical trials are recruiting in Kansas?

372 of the 743 studies on this page are recruiting new participants as of the 06 Oct 2026, 03:16 UTC sync. A further 10 have not yet opened recruitment, 347 are active but closed to new participants, and 14 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.