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Clinical Trials in the USA / NCT02951598
Active, not recruiting Observational

A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD)

NCT02951598 · tracked via the Priya Life Science USA tracker
Sponsor
Eli Lilly and Company
Phase
Observational
Started
2016-10-29
Last updated
2025-10-24

Condition(s) studied

Alzheimer DiseaseMild Cognitive Impairment

Investigational drug(s) / intervention(s)

Florbetapir F 18 PET Scan

Florbetapir F 18 PET Scan: Florbetapir F 18 positron emission tomography (PET) scan performed at baseline to confirm amyloid status. Participants who previously tested amyloid positive were exempt. No therapeutic investigational drug(s) intended to treat AD will be administered.

Study summary

The purpose of this study is to learn about health care use, costs, and clinical outcomes over time for amyloid positive participants with early stages of AD in the United States. This study is for research purposes only, and is not intended to treat any medical condition. No study therapy(ies) for AD will be administered.

Eligibility

Sex
ALL
Min age
55 Years
Max age
85 Years
Healthy volunteers
No
Inclusion Criteria: * Presents within normal course of outpatient care for whom the physician deems to meet clinical criteria for MCI due to AD or mild AD dementia. * Fully informed written consent of the participant (or his/her legal representative). * Study partner who has frequent contact with the participant is willing to accompany the participant at the study observations. * Fully informed written consent of the study partner; this person must be willing to serve as study partner for at least 6 months of the year. * Able to communicate in English and/or US Spanish. * Able to provide evidence of amyloid testing. * Has an Mini-Mental State Examination (MMSE) score of 20 or greater. Exclusion Criteria: * Are currently enrolled in any other clinical trial involving an investigational product or any other type of medical research judged not to be scientifically or medically compatible with this study at baseline. * Are investigator site personnel directly affiliated with this study and/or their immediate families. Immediate family is defined as a spouse, parent, child, or sibling, whether biological or legally adopted. * Lack of evidence of amyloid positivity through pre-study test. Note: After baseline assessment, participants with amyloid negativity identified as part of the study will not continue in post-baseline assessments. * Are Lilly employees or are employees of any third-party organization (TPO) involved in study who require exclusion of their employees.

Primary outcome measure(s)

Trial sites (77)

FacilityCityRegionStatus
California Pharmaceutical Research Institute Anaheim California
Advanced Research Center Anaheim California
Sun Valley Research Center Imperial California
Global Clinical Trials Irvine California
Irvine Clinical Research Center Irvine California
Alliance Research Centers Laguna Hills California
Pacific Clinical Studies, Inc Los Alamitos California
California Neurological Services, Inc. Panorama City California
Havana Research Institute Pasadena California
Clinical Innovations, Inc. Riverside California
Breakthrough Clinical Trials San Bernardino California
HB Clinical Trials Santa Ana California
Ventura Clinical Trials Ventura California
Colorado Neurological Institute Englewood Colorado
Coastal Connecticut Research, LLC New London Connecticut
JEM Research Institute Atlantis Florida
Visionary Investigators Network Aventura Florida
Research Alliance Clearwater Florida
Clinical Research of South Florida Coral Gables Florida
Infinite Clinical Research Doral Florida
International Research Partners, LLC. Doral Florida
Sarkis Clinical Trials Gainesville Florida
Indago Research & Health Center, Inc. Hialeah Florida
New Life Medical Research Center, Inc Hialeah Florida
Galiz Research Hialeah Florida
South Florida Clinical Trials Hialeah Florida
Van Buren Medical Hollywood Florida
Clinical Research of Homestead Homestead Florida
Jacksonville Center for Clinical Research Jacksonville Florida
Universal Neurological Care Jacksonville Florida
Sunrise Medical Research Lauderdale Lakes Florida
Biomed Research Institute Miami Florida
Miami Jewish Health Systems Miami Florida
Florida International Research Center Miami Florida
The Neurology Research Group, LLC Miami Florida
L&C Professional Medical Research Institute Miami Florida
Genoma Research Group, Inc. Miami Florida
Empire Clinical Research Miami Lakes Florida
Medical Research Group of Central Florida Orange City Florida
Combined Research Orlando Phase I-IV LLC Orlando Florida

+ 37 more sites — see the full list on the official registry below.

More Eli Lilly and Company trials in the USA

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT02951598 on ClinicalTrials.gov ↗ ← All trials in the USA