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Trackers› Clinical trials› Roma
Clinical trial register · Italy

Clinical Trials in Roma, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Italy and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6778 matching records held by the registry are in this view. Synced 08 Oct 2026, 03:19 UTC
6778
Studies in scope
all four open statuses
4069
Recruiting now
open to new participants
1018
Lead sponsors
across recruiting studies
Top sites
Milan 2843 Bologna 1305 Roma 1274 Naples 984 Rome 967
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS197 AstraZeneca72 Novartis Pharmaceuticals52 Janssen Research & Development, LLC44 Merck Sharp & Dohme LLC43
Site location
Milan2843 Bologna1305 Roma1274 Naples984 Rome967
All 489 locations
Target enrolment
to

Trials with a site in Roma

1274 of 6778 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Italy
Start
Active, closed
Vicore Pharma AB
Phase 2
378
Ancona, Bergamo, Monza, Roma, Turin
2024-12-09
Recruiting
Novartis Pharmaceuticals
Phase 3
60
Milan, Roma, Torino, Verona
2024-12-09
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
408
Roma
2024-12-06
Active, closed
PPM Services S.A.
Phase 3
400
Ancona, Florence, Genova, Parma, Pavia, Roma, Bologna, Catania
2024-12-05
Recruiting
Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational Study
NCT06689956FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Stage IA1 Endometrial Cancer FIGO 2023, Stage IA2 Endometrial Cancer FIGO 2023
Mayo Clinic
Observational
212
Verduno, Monza, Milan, Roma, Udine, Naples
2024-12-04
Active, closed
Janssen Research & Development, LLC
Phase 3
655
Milan, Palermo, Perugia, Pisa, Roma, Rozzano, Udine
2024-12-04
Recruiting
University Hospital Freiburg
Not applicable
20,000
Rome, Ferrara, Modena, Roma
2024-12-03
Active, closed
AstraZeneca
Phase 3
181
Bologna, Catania, Florence, Padua, Pisa, Roma, Rozzano
2024-12-03
Recruiting
Institut de Recherches Internationales Servier
Phase 3
48
Ancona, Bologna, Florence, Milan, Pavia, Roma, Torino
2024-12-03
Active, closed
Campus Bio-Medico University
Not applicable
60
Roma
2024-12-02
Recruiting
Novo Nordisk A/S
Phase 2
465
L’Aquila, Chieti, Bologna, Bergamo, Brescia, Milan, Pisa, Roma
2024-12-02
Active, closed
ViiV Healthcare
Phase 3
326
Bari, Bergamo, Milan, Roma
2024-12-02
Not yet open
Study on Fertility Parameters in Women With Germline Variants in BRCA1 and BRCA2
NCT06710015BRCA1 and/or BRCA2 Variant Carriers, Fertility, Reproductive Age, Menopause
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
128
Roma
2024-12-01
Not yet open
Artificial Intelligence-based Voice Assessment of Children and Adults Respiratory Conditions
NCT06630078Airway Disease, Cancer of Head and Neck, Radiotherapy, Bronchiolitis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
200
Roma
2024-11-30
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,006
Roma
2024-11-29
Recruiting
Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL
NCT06526793B-cell Non-Hodgkin Lymphoma, Follicular Lymphoma (FL), Large B-Cell Lymphoma (LBCL)
DrugSurovatamig
AstraZeneca
Phase 2
270
Alessandria, Bologna, Busto Arsizio, Milan, Roma
2024-11-27
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Early Phase 1
60
Roma
2024-11-25
Recruiting
Stereotactic Body Radiotherapy (SBRT) for Reirradiation of Inoperable Lung Lesions
NCT07401615Non Small Cell Lung Cancer, Pulmonary Stereotactic Radiotherapy
Istituto Clinico Humanitas
Observational
150
Bergamo, Bologna, Catania, Milan, Rozzano, Naples, Roma, Venezia
2024-11-25
Active, closed
DJO UK Ltd
Not applicable
64
Caserta, Milan, Roma
2024-11-23
Recruiting
Transcutaneous Auricular Vagus Nerve Stimulation for Treating Post-stroke Dysphagia
NCT06827301Dysphagia Following Cerebrovascular Accident
Campus Bio-Medico University
Not applicable
30
Roma
2024-11-23
Active, closed
BioMarin Pharmaceutical
Phase 2
30
Florence, Genova, Roma
2024-11-22
Recruiting
UCB Biopharma SRL
Phase 3
450
Brescia, Genova, Milan, Padova, Pisa, Roma, Rozzano
2024-11-21
Active, closed
Gilead Sciences
Phase 2/3
75
Milan, Roma
2024-11-20
Not yet open
Transit Time Flow Measurement in Coronary Surgery
NCT06471062Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
135
Roma
2024-11-20
Active, closed
Daiichi Sankyo
Phase 3
700
Bari, Brescia, Meldola, Milan, Novara, Palermo, Roma, Rome
2024-11-19
Recruiting
AstraZeneca
Phase 3
1,160
Florence, Legnano, Livorno, Monza, Orbassano, Padova, Peschiera del Garda, Roma
2024-11-18
Recruiting
Eli Lilly and Company
Phase 3
125
Florence, Modena, Novara, Parma, Roma, Verona
2024-11-18
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
20
Roma, Rome
2024-11-15
Active, closed
Pfizer
Phase 3
200
L’Aquila, Bari, Milan, Rome, Brescia, Latina, Pavia, Roma
2024-11-15
Recruiting
Rarecells Molecular Biomarkers for Early Detection of Lung Cancer
NCT06546007Lung Cancer, Pulmonary Neoplasm
Rarecells Diagnostics SAS
Observational
50
Roma
2024-11-13
Recruiting
argenx
Phase 2
81
Florence, Milan, Modena, Naples, Roma, Rozzano
2024-11-11
Active, closed
GlaxoSmithKline
Phase 2
283
Bergamo, Florence, Milan, Naples, Padova, Pisa, Roma
2024-11-11
Recruiting
Bayer
Phase 1
104
Roma, Rozzano
2024-11-08
Recruiting
Early Recognition of Progressive Lung Fibrosis in Systemic Rheumatic Diseases
NCT07541638Connective Tissue Diseases, Interstitial Lung Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
200
Roma
2024-11-07
Active, closed
Istituto Oncologico Veneto IRCCS
Phase 2
41
Bergamo, Roma, Rozzano, Aviano, Alessandria, Ferrara, Padova, Parma
2024-11-06
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
40
Roma
2024-11-06
Recruiting
Regina Elena Cancer Institute
Observational
103
Roma
2024-11-04
Recruiting
argenx
Observational
680
Bergamo, Bologna, Naples, Pisa, Roma
2024-11-04
Active, closed
Merck Sharp & Dohme LLC
Phase 1/2
180
Milan, Roma
2024-11-03
Recruiting
Azienda USL Reggio Emilia - IRCCS
Observational
40
Modena, Padova, Reggio Emilia, Roma
2024-11-02
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
200
Chieti, Milan, Messina, Roma
2024-11-01
Not yet open
Pregnancy in GUCH Patients
NCT06574386Congenital Heart Disease, Pregnancy Related, Infant Development, IUGR
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
70
Roma
2024-11-01
Recruiting
Advanced Surgical Simulation Processes in the Correction of Skeletal Defects and Deformities
NCT06380530Musculoskeletal Deformity, Musculoskeletal Abnormalities, Musculoskeletal Disorder
Istituto Ortopedico Rizzoli
Not applicable
100
Bologna, Rozzano, Genova, Milan, Pavia, Roma
2024-10-31
Recruiting
Istituto Ortopedico Rizzoli
Observational
1,000
Bologna, Genova, Milan, Pavia, Roma, Rozzano
2024-10-31
Recruiting
University of Florence
Observational
50
Roma
2024-10-30
Recruiting
Abivax S.A.
Phase 2
212
Bologna, Catanzaro, Milan, Negrar, Pavia, Roma, Rozzano, San Giovanni Rotondo
2024-10-30
Active, closed
A Study of Mosliciguat in PH-ILD
NCT06635850Pulmonary Hypertension, Interstitial Lung Disease, Lung Diseases, Vascular Diseases
DrugMosliciguat
Pulmovant, Inc.
Phase 2
135
Genova, Pavia, Naples, Palermo, Roma
2024-10-29
Recruiting
IRCCS Eugenio Medea
Not applicable
40
Bosisio Parini, Calambrone, Milan, Pavia, Roma, Salerno
2024-10-29
Recruiting
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
NCT06663332Crohns Disease, Colitis, Ulcerative, Arthritis, Psoriatic, Arthritis, Juvenile
DrugGuselkumab
Janssen Research & Development, LLC
Phase 3
196
Bergamo, Bologna, Roma, San Giovanni Rotondo, Trieste
2024-10-29
Recruiting
Minimally Invasive Simple Hysterectomy in Low Risk Cervical Cancer
NCT06416748Cervical Cancer, Cervix Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
974
Roma
2024-10-27
Recruiting
Novartis Pharmaceuticals
Phase 1/2
232
Foggia, Monza, Palermo, Pavia, Roma, Sassari, Ivrea, Trieste
2024-10-24
Recruiting
Gelsectan® in the Treatment of Patients With Diarrhoea-predominant Irritable Bowel Syndrome
NCT06681012Irritable Bowel Syndrome (IBS), Irritable Bowel Syndrome of Diarrhea Type (IBS-D)
Devintec Sagl
Not applicable
330
Bologna, Milan, Naples, Padova, Pavia, Pisa, Roma
2024-10-22
Recruiting
BioMarin Pharmaceutical
Phase 2
100
Florence, Roma, Genova
2024-10-21
Recruiting
Christian Cipriani
Not applicable
47
Acerenza, Milan, Roma, Salerno, Sant'Angelo dei Lombardi, Tricarico
2024-10-21
Active, closed
Industrial Farmacéutica Cantabria, S.A.
Phase 3
520
Roma
2024-10-17
Active, closed
Gruppo Italiano Malattie EMatologiche dell'Adulto
Phase 2
31
Florence, Lecce, Roma
2024-10-17
Active, closed
Uniquity One (UNI)
Phase 2
184
Milan, Campobasso, Padova, Roma, Pieve Emanuele, Verona
2024-10-16
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
200
Roma, Rome
2024-10-15
Active, closed
Evaluating the Role of IGF-1 and S-Klotho In Plaque Phenotype and Vulnerability: the VISION Study.
NCT06522074Ischemic Heart Disease, Chronic Coronary Syndrome, Optical Coherence Tomography (OCT)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
150
Roma
2024-10-15
Active, closed
Ipsen
Observational
424
Bergamo, Catania, Florence, Milan, Novara, Roma
2024-10-14
Recruiting
Catholic University of the Sacred Heart
Not applicable
50
Bologna, Roma
2024-10-14
Recruiting
Novartis Pharmaceuticals
Phase 2
200
Ancona, Milan, Rozzano, Modena, Palermo, Pavia, Roma, Verona
2024-10-09
Recruiting
AbbVie
Phase 2
488
Milan, Pavia, Roma
2024-10-07
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
126
Florence, Messina, Roma
2024-10-04
Recruiting
SoniVie Inc.
Not applicable
261
Mercogliano, Monza, Roma
2024-10-03
Recruiting
Primary Cardiac Lymphoma: Italian Multicenter Experience
NCT05819528Primary Cardiac Lymphoma
Fondazione Italiana Linfomi - ETS
Observational
43
Bergamo, Brescia, Ferrara, Milan, Perugia, Pisa, Roma, Sassari
2024-10-02
Active, closed
Teva Branded Pharmaceutical Products R&D LLC
Phase 2
349
Bologna, Catania, Milan, Padova, Roma, Salerno
2024-10-02
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
168
Roma
2024-10-01
Recruiting
Organoid Models of Hepatocellular Carcinoma
NCT06929845Hepatocellular Carcinoma, Organoids, Gut Microbiota, Tumor Microenvironment
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
150
Roma
2024-10-01
Not yet open
Transcatheter Treatment of Tricuspid Valve Regurgitation
NCT06093828Symptomatic Severe Tricuspid Regurgitation
TriFlo Cardiovascular, Inc.
Not applicable
40
Castel Volturno, Rozzano, San Donato Milanese, Roma
2024-10
Active, closed
Aortic Dissection fAlse enlarGement radIomics predictiOn
NCT07117825Dissection, Aortic Diseases, Aortic Dissection
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
500
Roma
2024-09-30
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Roma
2024-09-30
Recruiting
GlaxoSmithKline
Phase 1
845
Milan, Naples, Roma, Verona
2024-09-30
Active, closed
AstraZeneca
Phase 3
310
Florence, Orbassano, Roma, Verona
2024-09-30
Recruiting
GlaxoSmithKline
Phase 2
393
Bergamo, Bologna, Messina, Milan, Padova, Roma
2024-09-27
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
406
Salerno, Rome, Brescia, Milan, Ponderano (Biella), Roma
2024-09-26
Recruiting
Negative Antiphospholipid Syndrome: a Multicentric Study
NCT06373003Antiphospholipid Syndrome, Seronegative Antiphospholipid Syndrome
Italian Society for Rheumatology
Observational
105
Roma
2024-09-21
Recruiting
Janssen Research & Development, LLC
Phase 2/3
274
Ferrara, Milan, Naples, Roma
2024-09-19
Active, closed
argenx
Phase 3
141
Bergamo, Bologna, Milan, Naples, Roma
2024-09-18
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
2,700
Roma
2024-09-18
Active, closed
Zenas BioPharma (USA), LLC
Phase 2
190
Ferrara, Genova, Milan, Pisa, Roma, Torino, Verona
2024-09-17
Active, closed
GlaxoSmithKline
Phase 2
153
Genova, Milan, Naples, Roma, Sassari
2024-09-17
Active, closed
Novo Nordisk A/S
Phase 4
500
Florence, Milan, Roma, Trieste, Verona
2024-09-17
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Roma, Rome
2024-09-17
Recruiting
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
NCT06586515Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, Colorectal Cancer
DrugsLeucovorin·Cetuximab·Irinotecan·Adrucil
Eli Lilly and Company
Phase 1
630
Naples, Roma, Verona
2024-09-12
Active, closed
A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis
NCT06431373Uveitis, Posterior, Uveitis, Intermediate, Uveitis
Priovant Therapeutics, Inc.
Phase 3
371
Perugia, Milan, Reggio Emilia, Roma
2024-09-11
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
260
Roma
2024-09-09
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
500
Roma
2024-09-09
Recruiting
Valerio Nardone
Observational
1,000
Barletta, Campobasso, Lecce, Naples, Potenza, Roma
2024-09-06
Recruiting
Angela Toss
Observational
100
Genova, Milan, Modena, Padova, Roma
2024-09-05
Recruiting
Gossamer Bio USA, Inc.
Phase 3
330
Bologna, Naples, Pavia, Roma
2024-09-03
Recruiting
Recornea Srl
Not applicable
12
Roma
2024-09-03
By invitation
Giovanni Di Perri
Observational
200
Genova, Milan, Torino, Bari, Catania, Naples, Padova, Roma
2024-09-02
Not yet open
In Vitro Models From Pediatric Brain Tumors
NCT06499636Glioma, Malignant, Ependymoma, Medulloblastoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Roma
2024-09-01
Recruiting
Post-Extraction Healing: microRepair vs Chlorhexidine
NCT07555366Endodontic Issue, Periodontal Issues
University of Roma La Sapienza
Not applicable
30
Roma
2024-09-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Roma
2024-09-01
Recruiting
CRS Questionnaire Validation Project
NCT06970977Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
The European Forum for Research and Education in Allergy and Airway Diseases
Observational
1,000
Roma
2024-09-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
220
Roma
2024-09-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
24
Roma
2024-09-01
Recruiting
Post-Transplant Diabetes Outcomes Prediction
NCT07512804New Onset Diabetes After Transplantation
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
120
Roma
2024-08-31
Active, closed
Non-invasive Tests for Non-alcoholic Steato-hepatitis
NCT07502755NASH With Fibrosis, Diabete Type 2, Obesity
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
828
Roma
2024-08-31
Recruiting
Multidimensional Omics Analysis in Malignant Pleural Mesothelioma
NCT07561190Malignant Pleural Mesothelioma (MPM)
Azienda USL Reggio Emilia - IRCCS
Observational
300
Catania, Naples, Reggio Emilia, Roma
2024-08-30
Recruiting
Impact of Trans-catheter Aortic Valve Implantation on Renal Function
NCT07626710Aortic Valve Stenosis, Chronic Kidney Diseases, Renal Failure Acute Chronic
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Roma
2024-08-30
Active, closed
Phase IIa Study Evaluating AZD7798 in Crohn's Disease
NCT06450197Moderate to Severe Crohn's Disease
DrugAZD7798
AstraZeneca
Phase 2
120
Milan, Roma, Rome
2024-08-28
Active, closed
Gilead Sciences
Phase 3
640
Aviano, Florence, Lecco, Meldola, Milan, Padova, Pisa, Roma
2024-08-28
Active, closed
Zenas BioPharma (USA), LLC
Phase 2
93
Cefalù, Florence, Pozzilli, Roma
2024-08-26
Active, closed
Kite, A Gilead Company
Phase 3
452
Milan, Bologna, Roma, Torino
2024-08-23
Active, closed
United Pharmaceuticals
Not applicable
70
Roma
2024-08-14
Recruiting
AstraZeneca
Phase 3
620
Florence, Milan, Naples, Padova, Roma, Rozzano, Tricase
2024-08-12
Active, closed
EyeBiotech Ltd.
Phase 2/3
984
Bologna, Florence, Milan, Roma, Rome, Udine
2024-08-07
Active, closed
Pfizer
Observational
450
Bari, Rozzano, Bologna, Catania, Roma, Rome
2024-08-07
Active, closed
Servier Bio-Innovation LLC
Phase 1/2
102
Aviano, Meldola, Milan, Naples, Perugia, Roma, Rozzano
2024-08-07
Recruiting
VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease
NCT06257706Moderately to Severely Active Crohn's Disease, Crohn Disease, Disease Crohn
DrugVedolizumab
Alimentiv Inc.
Phase 4
304
San Giovanni Rotondo, Milan, Roma
2024-08-07
Not yet open
EC_ItaLynch: Mainstreaming the Diagnosis of Lynch Syndrome
NCT06501417Lynch Syndrome, Endometrial Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
600
Roma
2024-08-01
Active, closed
Fidia Farmaceutici s.p.a.
Not applicable
156
Bologna, Florence, Padova, Pavia, Roma, Torino, Milan
2024-08-01
Active, closed
Bambino Gesù Hospital and Research Institute
Observational
14
Roma
2024-08-01
Active, closed
Novartis Pharmaceuticals
Phase 3
146
Bologna, Florence, Genova, Milan, Palermo, Roma, Orbassano
2024-07-31
Recruiting
NovoCure GmbH
Phase 3
734
Alessandria, Bergamo, Ferrara, Meldola, Pesaro, Roma, Rome, Siena
2024-07-31
Active, closed
Annexon, Inc.
Phase 3
659
Florence, Milan, Roma, Rome
2024-07-30
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
160
Roma
2024-07-25
Recruiting
Janssen Research & Development, LLC
Phase 3
752
Brescia, Catania, Chieti, Genova, Monza, Pisa, Roma, Salerno
2024-07-25
Recruiting
CellFX® Nanosecond Pulsed Field Ablation (PFA) 360 Catheter Ablation System for Treatment of Atrial Fibrillation
NCT06696170Atrial Fibrillation Paroxysmal, Cardiac Ablation, Cardiac Arrhythmia
Pulse Biosciences, Inc.
Not applicable
60
Roma
2024-07-25
Recruiting
A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors
NCT06427941Metastatic Hepatocellular Carcinoma, Local Advanced Hepatocellular Carcinoma, Alpha-fetoprotein (AFP)-Producing Gastric Cancer, Extragonadal Yolk Sac Tumors
DrugsTislelizumab·Bevacizumab
BeOne Medicines
Phase 1/2
630
Naples, Padova, Roma, Rozzano
2024-07-23
Active, closed
Ferrer Internacional S.A.
Phase 2
241
Bologna, Padova, Pisa, Roma, Salerno
2024-07-23
Active, closed
Arrowhead Pharmaceuticals
Phase 3
446
Rozzano, Palermo, Bologna, Brescia, Milan, Roma
2024-07-22
Active, closed
MedSIR
Phase 2
165
Bergamo, Milan, Novara, Roma
2024-07-22
Recruiting
GlaxoSmithKline
Phase 3
150
Catania, Genova, Roma, Rozzano
2024-07-19
Recruiting
Jazz Pharmaceuticals
Phase 3
286
Monserrato, Candiolo, Genova, Milan, Naples, Padova, Pisa, Roma
2024-07-19
Recruiting
Digital diagnoSis of Cardiac sOUNd in peDiatric Patients [DI-SOUND Study]
NCT07542509Cardiac Disease, Auscultation of Heart, Machine Learning
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
1,000
Bologna, Milan, Roma, Naples
2024-07-18
Recruiting
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
Phase 2
385
Bologna, Brescia, Catanzaro, Milan, Negrar, Padova, Roma, Rozzano
2024-07-18
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
36
Roma
2024-07-17
Recruiting
Heidelberg University
Observational
4,000
Calambrone, Conegliano, Pisa, Roma
2024-07-16
Active, closed
Merck Sharp & Dohme LLC
Phase 3
300
Florence, Alessandria, Bologna, Milan, Pavia, Roma, Varese
2024-07-16
Active, closed
Fidia Farmaceutici s.p.a.
Not applicable
72
Milan, Naples, Roma, Torino
2024-07-12
Recruiting
Fibrosis Lessens After Metabolic Surgery
NCT06374875Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis
The Cleveland Clinic
Phase 4
120
Milan, Roma
2024-07-11
Active, closed
GRIN Therapeutics, Inc.
Phase 1/2
30
Genoa, Florence, Roma
2024-07-10
Active, closed
UCB Biopharma SRL
Phase 3
70
Roma
2024-07-10
Recruiting
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen
NCT06127407Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
DrugIvosidenib
Servier Bio-Innovation LLC
Phase 3
136
Bologna, Milan, Orbassano, Padova, Palermo, Prato, Roma
2024-07-09
Recruiting
GlaxoSmithKline
Phase 1
675
Aviano PN, Milan, Naples, Roma
2024-07-02
Active, closed
AstraZeneca
Phase 3
339
Brescia, Cona, Florence, Milan, Naples, Reggio Emilia, Roma, Rome
2024-06-29
Recruiting
Institution of an Italian Registry and Biobank for Biological Sample Collection
NCT06892964Lymphatic Malformation, Lymphatic Abnormality, Lymphangioma, Lymphatic Abnormalities
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
70
Roma
2024-06-27
Active, closed
UCB Biopharma SRL
Phase 3
176
Ancona, Località Torrette, Catania, Pisa, Roma
2024-06-25
Active, closed
Merus B.V.
Phase 3
621
Brescia, Cuneo, Milan, Naples, Roma, Rozzano
2024-06-25
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
220
Milan, Roma
2024-06-20
By invitation
Sarepta Therapeutics, Inc.
Phase 1/2
60
Milan, Roma
2024-06-19
Recruiting
Boehringer Ingelheim
Phase 3
6,712
Bergamo, Foggia, Genova, Naples, Pavia, Roma, Rozzano
2024-06-17
Recruiting
Oncoinvent Solutions AS
Phase 2
114
Roma
2024-06-15
Active, closed
Merck Sharp & Dohme LLC
Phase 3
550
Bari, Milan, Florence, Roma
2024-06-11
Recruiting
LEO Pharma
Phase 3
195
Ancona, Brescia, Padova, Roma, Rome
2024-06-10
Recruiting
X4 Pharmaceuticals
Phase 3
176
Torrette, Brescia, Genova, Meldola, Monza, Roma, Torino
2024-06-06
Recruiting
Markers of Favorable Response to Complement Inhibitors Therapy
NCT06455709Myasthenia Gravis, Generalized
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
50
Roma
2024-06-05
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase 2
25
Milan, Roma, Tricase
2024-06-03
Recruiting
Prevalence of Sarcopenic Obesity in COPD
NCT06822504Sarcopenic Obesity, COPD
IRCCS San Raffaele Roma
Observational
236
Roma
2024-06-01
Active, closed
Stealth BioTherapeutics Inc.
Phase 3
313
Milan, Roma, Udine
2024-05-30
Recruiting
Harmony Biosciences Management, Inc.
Phase 3
134
Florence, Genova, Milan, Padova, Roma, Trieste
2024-05-28
Recruiting
Société des Produits Nestlé (SPN)
Not applicable
380
Cefalù, Genova, Palermo, Roma, Tricase
2024-05-24
Recruiting
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
NCT06419374Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
DrugPegozafermin
89bio, Inc.
Phase 3
762
Bergamo, Foggia, Milan, Novara, Palermo, Roma, Rome, Rozzano
2024-05-24
Recruiting
Novartis Pharmaceuticals
Phase 3
550
Cona, Pisa, Roma, Torino
2024-05-21
Recruiting
Laterza Lucrezia
Observational
20
Roma
2024-05-20
Recruiting
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
NCT06237452Clostridium Difficile, Clostridium Difficile Infections, Clostridium Difficile Infection Recurrence, Clostridioides Difficile Infection
Vedanta Biosciences, Inc.
Phase 3
852
Alessandria, Lecco, Milan, Monza, Naples, Pavia, Modena, Roma
2024-05-20
Recruiting
NMD Pharma A/S
Phase 2
84
Bergamo, Bologna, Genova, Milan, Naples, Pisa, Roma
2024-05-16
Active, closed
The OPBC-07/microNAC Study
NCT06529302Breast Cancer
University Hospital, Basel, Switzerland
Observational
2,000
Milan, Naples, Padova, Pavia, Roma
2024-05-15
Active, closed
Boehringer Ingelheim
Phase 2
190
Florence, Milan, Naples, Roma, Rozzano, Torrette Di Ancona
2024-05-15
Active, closed
Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients
NCT06414044Migraine, Migraine With Aura, Migraine Without Aura, Chronic Migraine
DrugAtogepant
University of Florence
Observational
500
Florence, Roma
2024-05-09
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
148
Roma
2024-05-06
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
207
Roma
2024-05-02
Active, closed
Eli Lilly and Company
Phase 3
10,000
Bologna, Ferrara, Genova, Milan, Palermo, Perugia, Pisa, Roma
2024-04-30
Active, closed
Erasca, Inc.
Phase 3
78
Milan, Roma, Udine
2024-04-29
Recruiting
Janssen Research & Development, LLC
Phase 3
641
Arezzo, Bergamo, Brescia, Milan, Roma, Rozzano, Torino
2024-04-18
Active, closed
Janssen-Cilag Ltd.
Phase 3
120
Bologna, Milan, Naples, Pontedera Pisa, Rho, Roma, Rozzano, San Giovanni Rotondo
2024-04-17
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,200
Meldola, Aviano, Milan, Rozzano, Bologna, Genova, Roma
2024-04-14
Recruiting
AstraZeneca
Phase 3
675
Bergamo, Genoa, Milan, Monza, Padova, Pavia, Ravenna, Roma
2024-04-11
Active, closed
Janssen Research & Development, LLC
Phase 3
272
Arezzo, Milan, Province of Macerata, Ravenna, Roma, Rozzano, Torino
2024-04-09
Active, closed
HAP/VAP Diagnosis in Critically Ill Septic Patients Using a Multiplex PCR Array
NCT05952648HAP - Hospital Acquired Pneumonia, VAP - Ventilator Associated Pneumonia
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
126
Bologna, Florence, Modena, Roma
2024-04-03
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
10,000
Roma
2024-04-01
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Roma
2024-04-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
2,400
Roma
2024-03-31
Active, closed
Gilead Sciences
Phase 2
228
Bologna, Cagliari, Catanzaro, Milan, Negrar, Padova, Palermo, Roma
2024-03-27
Active, closed
Gilead Sciences
Phase 3
577
Brescia, Foggia, Milan, Monza, Pavia, Roma
2024-03-25
Recruiting
GlaxoSmithKline
Phase 3
864
Bolzano, Bologna, Milan, Naples, Pavia, Prato, Roma, Rozzano MI
2024-03-21
Active, closed
GlaxoSmithKline
Phase 4
336
Genova, Monserrato CA, Naples, Pieve Di Soligo TV, Roma, Rozzano, Verona
2024-03-20
Recruiting
Verastem, Inc.
Phase 3
270
Aviano, Brescia, Catania, Milan, Naples, Padova, Roma, Rome
2024-03-18
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
278
Roma
2024-03-15
Recruiting
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3
411
Bologna, Legnago, Milan, Padova, Roma
2024-03-15
Recruiting
AstraZeneca
Phase 3
100
Florence, Genova, Milan, Padova, Roma
2024-03-14
Recruiting
Janssen Research & Development, LLC
Phase 3
120
Alessandria, Bergamo, Bologna, Florence, Milan, Roma
2024-03-13
Recruiting
Eli Lilly and Company
Phase 3
90
Alessandria, Bergamo, Bologna, Florence, Milan, Roma
2024-03-13
Recruiting
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
NCT06318169Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
DrugPegozafermin
89bio, Inc.
Phase 3
1,350
Bergamo, Foggia, Milan, Modena, Naples, Novara, Palermo, Roma
2024-03-13
Recruiting
Novartis Pharmaceuticals
Phase 3
450
Brescia, Cona, Genova, Milan, Rozzano, Pisa, Roma, Negrar
2024-03-12
Recruiting
Regina Elena Cancer Institute
Observational
18
Roma
2024-03-07
Recruiting
Takeda
Phase 2
268
Bologna, Milan, Palermo, Roma, Rome, Rozzano
2024-03-05
By invitation
Sarepta Therapeutics, Inc.
Phase 1/2
78
Gussago, Milan, Pisa, Roma
2024-03-04
Active, closed
Cynata Therapeutics Limited
Phase 2
60
Ancona, Milan, Roma, Rozzano, San Giovanni Rotondo, Venezia
2024-03-04
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
300
Roma
2024-03-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
510
Roma
2024-03-01
Active, closed
Changing the Future of Intestinal Failure in Intestinal Chronic Inflammation (INT-FAIL)
NCT06777251Intestinal Failure, Inflammatory Bowel Diseases, Crohn Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
254
Roma
2024-02-29
Recruiting
Novartis Pharmaceuticals
Phase 3
50
Ranica, Milan, Roma
2024-02-28
Recruiting
Daiichi Sankyo
Phase 2/3
860
Aviano, Bologna, Catania, Florence, Milan, Monza, Naples, Roma
2024-02-27
Recruiting
Kura Oncology, Inc.
Phase 1
171
Bologna, Ravenna, Roma
2024-02-22
Active, closed
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
762
Meldola (Fc), Milan, Monza, Genova, Brescia, Roma, Ancona, Aviano (PN)
2024-02-21
Recruiting
Italfarmaco
Phase 3
138
Lecco, Milan, Padova, Roma
2024-02-19
Not yet open
Severity Over Time of Early Forms of Spondyloarthritis
NCT06261931Spondyloarthritis, Spondyloarthritis, Axial
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
387
Roma
2024-02-12
Active, closed
Boehringer Ingelheim
Phase 3
428
Bari, Candiolo (TO), Catania, Naples, Parma, Roma, Varese
2024-02-09
Recruiting
FMT to Eradicate Intestinal Colonization by Carbapenem-resistant Enterobacteriaceae
NCT05791396Enterobacteriaceae Infections, Multi-antibiotic Resistance
DrugDonor - FMT
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase 1/2
36
Roma
2024-02-08
Recruiting
Meyer Children's Hospital IRCCS
Observational
90
Florence, Roma, Foggia, Palermo
2024-02-07
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
24
Roma
2024-02-07
Active, closed
Genmab
Phase 3
1,095
Rozzano, Candiolo, Bologna, Catania, Palermo, Reggio Emilia, Roma
2024-02-05
Recruiting
Spatial Radiogenomics of Ovarian Cancer
NCT06324175Ovarian Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
24
Roma
2024-02-01
Active, closed
Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)
NCT05853575Advanced Cancer, Metastatic Cancer, Malignant Neoplasm of Lung
DrugAdagrasib
Mirati Therapeutics Inc.
Phase 2
200
Pesaro, Novara, Candiolo, Milan, Perugia, Roma
2024-02-01
Active, closed
Astellas Gene Therapies
Not applicable
119
Florence, Gussago, Messina, Milan, Pavia, Pisa, Roma, Udine
2024-02-01
Recruiting
Catholic University of the Sacred Heart
Observational
300
Roma
2024-01-31
Active, closed
Incyte Corporation
Phase 3
617
Ancona, Catania, Milan, Pisa, Roma, Rozzano
2024-01-30
Recruiting
CarThera
Phase 3
560
Bologna, Livorno, Padua, Roma, Rozzano, Torino
2024-01-29
Recruiting
Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment
NCT07500324Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), Retinal Detachment
Fondazione G.B. Bietti, IRCCS
Not applicable
260
Roma
2024-01-24
Active, closed
Janssen Research & Development, LLC
Phase 3
112
Bergamo, Bologna, Florence, Pescara, Roma, San Giovanni Rotondo, Trieste
2024-01-19
Recruiting
Azienda Ospedaliero-Universitaria di Modena
Not applicable
30
Roma, Trieste, Modena, Naples
2024-01-17
Recruiting
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
NCT06064877Metastatic Head-and-neck Squamous-cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
DrugsErbitux·Cetuximab
AVEO Pharmaceuticals, Inc.
Phase 3
410
Bologna, Florence, Milan, Novara, Padua, Pavia, Roma
2024-01-11
Active, closed
AbbVie
Phase 2/3
89
Rozzano, Milan, Naples, Rome, Bologna, Palermo, Roma
2024-01-11
Recruiting
Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers
NCT06840119Cancer, HLA-A*02:01-positive
Immunocore Ltd
Phase 1/2
600
Roma, Rozzano
2024-01-10
Recruiting
Translumina Therapeutics Pvt Ltd.
Observational
2,000
Campobasso, Mercogliano AV, Naples, Padova, Pescara, Roma
2024-01-10
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
80
Roma
2024-01-08
Recruiting
Ryvu Therapeutics SA
Phase 2
98
Meldola, Ancona, Bologna, Brescia, Lecce, Ravenna, Roma, Rozzano
2024-01-05
Recruiting
Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse Remodeling
NCT06356727Heart Failure, Left Ventricular Dysfunction, Idiopathic Dilated Cardiomyopathy
Azienda Ospedaliera Universitaria Integrata Verona
Not applicable
190
Ferrara, Genova, Milan, Naples, Roma, Rome, Torino, Verona
2024-01-03
Active, closed
Novartis Pharmaceuticals
Phase 2
49
Genova, Milan, Roma, Naples
2024-01-03
Recruiting
Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine
NCT07159750Migraine, Episodic Migraine, Chronic Migraine, Headache
Hospital Universitari Vall d'Hebron Research Institute
Observational
700
L’Aquila, Modena, Pavia, Roma
2024-01-02
Recruiting
Post-Debonding Finishing in Orthodontics
NCT07534423Caries, Enamel Lesions
University of Roma La Sapienza
Observational
100
Roma
2024-01-01
Recruiting
HF vs NIV in Acute Cardiogenic Pulmonary Edema
NCT05989139Pulmonary Edema Cardiac Cause
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
30
Roma
2024-01-01
Recruiting
Federico II University
Not applicable
100
Naples, Novara, Pisa, Roma
2023-12-29
Recruiting
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
NCT06137118B-cell Acute Lymphoblastic Leukemia (B-ALL)
DrugSurovatamig
AstraZeneca
Phase 1/2
255
Bergamo, Bologna, Monza, Naples, Roma
2023-12-29
Recruiting
Bristol-Myers Squibb
Phase 1/2
460
Bologna, Brescia, Milan, Pisa, Ravenna, Roma, Verona
2023-12-29
Active, closed
Boston Scientific Corporation
Not applicable
484
Ancona, Milan, Cotignola, Roma
2023-12-28
Recruiting
Eli Lilly and Company
Phase 3
1,264
Bari, Bologna, Catania, Milan, Naples, Padova, Roma, Rome
2023-12-21
Recruiting
PARa-aOrtic LymphAdenectomy in Locally Advanced Cervical Cancer
NCT05581121Cervical Carcinoma, Adenocarcinoma, Adenosquamous Carcinoma
Institut Claudius Regaud
Phase 3
510
Roma
2023-12-20
Recruiting
Janssen Research & Development, LLC
Phase 3
120
Roma
2023-12-20
Active, closed
Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis
NCT06046222Eosinophilic Granulomatosis With Polyangiitis, Churg-Strauss Syndrome
NS Pharma, Inc.
Phase 2
45
Milan, Roma, Trento, Verona
2023-12-20
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
30
Roma
2023-12-19
Recruiting
Next-Generation alzheImer'S Therapeutics
NCT06372587Alzheimer Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
14
Roma
2023-12-19
Active, closed
REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors)
NCT05973773Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation
DrugZipalertinib
Taiho Oncology, Inc.
Phase 3
285
Meldola, Genova, Milan, Modena, Pavia, Ravenna, Roma, Verona
2023-12-18
Recruiting
Merck Sharp & Dohme LLC
Phase 3
614
Bari, Meldola, Udine, Milan, Bergamo, Catanzaro, Florence, Roma
2023-12-15
Active, closed
Deciphera Pharmaceuticals, LLC
Phase 3
54
Naples, Palermo, Bologna, Milan, Padova, Roma, Rozzano
2023-12-13
Active, closed
Aura Biosciences
Phase 3
108
Florence, Milan, Roma
2023-12-06
Active, closed
Gilead Sciences
Phase 2
176
Catanzaro, Milan, Roma, Rozzano
2023-12-05
Recruiting
The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study
NCT05847387Corneal Transplant Failure, Corneal Endothelial Cell Loss
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Observational
135
Brescia, Bologna, Catanzaro, Roma, Venice, Vicenza
2023-12-01
Recruiting
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
100
Bologna, Careggi, Rozzano, Milan, Padova, Palermo, Prato, Roma
2023-12-01
Recruiting
Multicenter Evaluation of Patients Using LATITUDE Monitoring System
NCT06311149Cardiovascular Diseases, Arrhythmias, Cardiac, Heart Failure, Sudden Cardiac Death
University Hospital of Ferrara
Observational
20,000
Ferrara, Naples, Roma
2023-12-01
Recruiting
argenx
Observational
279
Roma
2023-11-30
Recruiting
Sanofi
Observational
230
Bologna, Brescia, Florence, Milan, Naples, Roma, Verona
2023-11-30
Active, closed
424 General Military Hospital
Observational
122
Milan, Roma, Siena, Udine
2023-11-28
Recruiting
BioMarin Pharmaceutical
Observational
400
Genoa, Roma, Milan, Rome
2023-11-27
Recruiting
Biologic Characterization of Patients With ITP
NCT05694325Immune Thrombocytopenia
Gruppo Italiano Malattie EMatologiche dell'Adulto
Not applicable
200
Bologna, Piacenza, Roma, Torino, Trieste
2023-11-27
Recruiting
424 General Military Hospital
Observational
150
Milan, Roma, Siena, Udine
2023-11-25
Recruiting
Novartis Pharmaceuticals
Phase 2/3
232
Bologna, Milan, Roma, Torino, Naples
2023-11-24
Recruiting
AstraZeneca
Phase 3
625
Bergamo, Empoli, Milan, Modena, Naples, Padova, Reggio Emilia, Roma
2023-11-23
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
108
Roma
2023-11-16
Active, closed
Novartis Pharmaceuticals
Phase 3
470
Milan, Rozzano, Modena, Roma, Siena
2023-11-15
Recruiting
ACP-204 in Adults With Alzheimer's Disease Psychosis
NCT06159673Alzheimer's Disease Psychosis
DrugACP-204
ACADIA Pharmaceuticals Inc.
Phase 2/3
1,074
Brescia, Cefalù, Isernia, Milan, Roma, Salerno, Torino, Tricase
2023-11-14
Active, closed
AstraZeneca
Phase 3
1,902
Empoli, Lucca, Milan, Modena, Naples, Padova, Province of Macerata, Roma
2023-11-14
Recruiting
HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies
NCT05658640Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory
DrugsTrametinib·Cytarabine·Dexamethasone·Cyclophosphamide
Princess Maxima Center for Pediatric Oncology
Phase 1/2
26
Genova, Monza, Padova, Roma, Turin
2023-11-14
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
126
Florence, Messina, Roma
2023-11-13
Recruiting
GD2-CAR T Cells for Pediatric Brain Tumours
NCT05298995Brain Tumor, Pediatric, Medulloblastoma, Childhood, Embryonal Tumor, High Grade Glioma
DrugGD2-CART01
Bambino Gesù Hospital and Research Institute
Phase 1
54
Roma
2023-11-09
Active, closed
AstraZeneca
Phase 3
314
Ancona, Brescia, Cona, Milan, Padova, Roma
2023-11-08
Active, closed
Pfizer
Phase 3
1,571
L’Aquila, Florence, Milan, Roma, Rome, Cagliari
2023-11-08
Active, closed
AstraZeneca
Phase 3
1,835
Bergamo, Bologna, Foggia, Genoa, Naples, Pisa, Roma, Torino
2023-11-07
Recruiting
IRCCS San Raffaele Roma
Observational
192
Roma
2023-11-07
Active, closed
Bristol-Myers Squibb
Phase 2
100
Bergamo, Meldola, Milan, Padova, Roma, Torino, Naples
2023-11-06
Active, closed
TheraSphere With Durvalumab and Tremelimumab for HCC
NCT05063565Hepatocellular Carcinoma
Boston Scientific Corporation
Phase 2
100
Milan, Roma, Udine
2023-11-03
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Roma
2023-11-01
Not yet open
University of Dublin, Trinity College
Phase 3
952
Roma
2023-11
Active, closed
IDEAYA Biosciences
Phase 2/3
420
Milan, Naples, Roma, Siena
2023-10-31
Recruiting
United Therapeutics
Phase 3
698
Catania, Forlì, Modena, Monza, Roma, Siena, Verona
2023-10-30
Active, closed
A Multi-Dimensional Model of cAre and transItion for Patients With cOmplex RAre Diseases
NCT07558213Rare Diseases, Mitochondrial Diseases, Muscular Dystrophies, Dysmorphic Disorder, Body
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
136
Roma
2023-10-29
Recruiting
Grupo Espanol de Tumores Neuroendocrinos
Phase 3
170
Reggio Emilia, Bari, Meldola, Milan, Roma, Verona
2023-10-27
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
142
Roma
2023-10-25
Active, closed
Bristol-Myers Squibb
Phase 3
1,057
Ancona, Modena, Florence, Milan, Pisa, Roma, Trieste, Bergamo
2023-10-25
Active, closed
Bristol-Myers Squibb
Phase 3
402
Rome, Milan, Rozzano, Turin, Florence, Bologna, Reggio Calabria, Roma
2023-10-24
Active, closed
AstraZeneca
Phase 3
895
Bari, Bergamo, Milan, Padova, Parma, Pavia, Ravenna, Roma
2023-10-24
Active, closed
A Study to Investigate Efficacy and Safety of BCL2 Inhibitor Sonrotoclax as Monotherapy and in Combination With Zanubrutinib in Adults With Waldenström Macroglobulinemia
NCT05952037Waldenstrom Macroglobulinemia, Waldenstrom's Macroglobulinemia Recurrent, Waldenstrom's Macroglobulinemia Refractory
DrugsSonrotoclax·Zanubrutinib
BeOne Medicines
Phase 2
114
Bologna, Brescia, Milan, Pavia, Roma, Udine
2023-10-23
Recruiting
W.L.Gore & Associates
Not applicable
244
Milan, Perugia, Roma, Turin
2023-10-17
Active, closed
Celgene
Phase 3
79
Rozzano, Bologna, Roma
2023-10-16
Active, closed
Ipsen
Phase 3
759
Bologna, Naples, Pavia, Pozzilli, Roma
2023-10-12
Active, closed
Janssen Research & Development, LLC
Phase 3
684
Palermo, Parma, Roma, Rozzano
2023-10-12
Recruiting
Novartis Pharmaceuticals
Phase 3
106
Bari, Ranica, Brescia, Milan, Roma, Torino, Naples
2023-10-02
Recruiting
Abbott Medical Devices
Observational
1,000
Brescia, Castel Volturno, Milan, Palermo, Roma, San Donato Milanese, Torino
2023-09-29
Active, closed
Tensive SRL
Not applicable
92
Rozzano, Catania, Milan, Pavia, Pisa, Roma, Torino
2023-09-29
By invitation
Sarepta Therapeutics, Inc.
Phase 3
400
Genova, Milan, Roma
2023-09-27
Active, closed
Campus Bio-Medico University
Not applicable
42
Roma
2023-09-22
Active, closed
AbbVie
Phase 2
130
Florence, Milan, Naples, Bologna, Palermo, Roma
2023-09-21
Recruiting
Technological Balance and Gait Rehabilitation in Patients With Multiple Sclerosis.
NCT05983809Multiple Sclerosis, Balance, Cognitive Impairment
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
24
Roma
2023-09-15
Active, closed
Bristol-Myers Squibb
Phase 3
1,255
Bologna, Modena, Florence, Milan, Pisa, Roma, Ancona, Bergamo
2023-09-14
Recruiting
A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease
NCT05878717Systemic Sclerosis Associated Interstitial Lung Disease, Scleroderma, Systemic
DrugBelimumab
GlaxoSmithKline
Phase 2/3
300
Roma, Ancona, Bari, Cagliari, Catania, Ferrara, Florence, Milan
2023-09-13
By invitation
argenx
Phase 3
240
Bari, Milan, Pisa, Roma, Rozzano, Udine
2023-09-12
Recruiting
European Breast Cancer Research Association of Surgical Trialists
Observational
1,236
Milan, Roma
2023-09-12
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
50
Roma
2023-09-11
Recruiting
The ReTAVI Prospective Observational Registry
NCT05601453Structural Valve Deterioration, Structural Valve Degeneration, Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction
Institut für Pharmakologie und Präventive Medizin
Observational
250
Ancona, Bologna, Brescia, Florence, Milan, Padua, Pisa, Roma
2023-09-05
Recruiting
National Cancer Institute, Naples
Phase 2
38
Naples, Roma, Torino, Verona
2023-09-01
Active, closed
University of Roma La Sapienza
Not applicable
40
Roma
2023-09-01
Recruiting
A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)
NCT06051409Ph+ ALL, Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
DrugOlverembatinib
Ascentage Pharma Group Inc.
Phase 3
350
Bologna, Meldola, Milan, Monza, Ravenna, Roma, Torino, Varese
2023-08-31
Active, closed
AnaptysBio, Inc.
Phase 2
420
Milan, Pavia, Bari, Novara, Roma
2023-08-31
Active, closed
Cytokinetics
Phase 3
500
San Donato Milanese, Brescia, Florence, Foggia, Milan, Naples, Pisa, Roma
2023-08-31
By invitation
Disc Medicine, Inc
Phase 2/3
230
Roma
2023-08-31
Recruiting
AstraZeneca
Phase 3
231
Genova, Pavia, Roma
2023-08-24
Active, closed
Emalex Biosciences Inc.
Phase 3
150
Genova, Naples, Roma, Catania, Milan
2023-08-16
Recruiting
Ponatinib in Chronic Myeloid Leukemia Patients in Chronic Phase
NCT06119269Chronic Myeloid Leukemia, Chronic Phase
University of Pisa
Observational
100
Cagliari, Milan, Naples, Pisa, Roma
2023-08-02
Recruiting
GlaxoSmithKline
Phase 3
892
Cagliari, Genova, Milan, Naples, Padova, Pisa, Reggio Emilia, Roma
2023-08-01
Recruiting
Ischemic And Bleeding Risk Assessment After TAVR
NCT06000943Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement
Niguarda Hospital
Observational
2,500
Milan, Rozzano, San Donato Milanese, Genova, Potenza, Roma, Torino
2023-08-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
383,980
Roma
2023-07-25
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
1,020
Roma
2023-07-24
Active, closed
Gruppo Italiano Malattie EMatologiche dell'Adulto
Phase 2
78
Florence, Meldola, Perugia, Ravenna, Rimini, Roma, Siena
2023-07-21
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
34
Roma
2023-07-18
Active, closed
Mineralys Therapeutics Inc.
Phase 3
1,076
Bologna, Ferrara, Genova, Messina, Pisa, Roma
2023-07-14
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Roma
2023-07-10
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
85
Roma
2023-07-03
Recruiting
International Cardiac Amyloidosis Registry
NCT06894290Cardiac Amyloidosis
Leiden University Medical Center
Observational
300
Roma
2023-06-30
Recruiting
Friedreich's Ataxia Research Alliance
Observational
3,000
Conegliano, Milan, Roma
2023-06-28
Recruiting
Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary Interventions
NCT05732701Percutaneous Coronary Intervention, Platelet Aggregation Inhibitors, Coronary Artery Disease
Insel Gruppe AG, University Hospital Bern
Not applicable
2,788
Roma
2023-06-27
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 3
12
Milan, Roma, Torino
2023-06-24
Recruiting
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
NCT05427370Coronary Artery Disease, Heart Failure Systolic
Sunnybrook Health Sciences Centre
Not applicable
754
Roma
2023-06-22
Active, closed
Bristol-Myers Squibb
Phase 3
1,230
Catania, Florence, Genova, Milan, Pisa, Roma, Torino, Naples
2023-06-22
Recruiting
Study of Loncastuximab Tesirine in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) or High-Grade B-Cell Lymphoma (HGBCL) Following CAR-T Therapy Failure
NCT06918912Diffuse Large B-Cell Lymphoma, High-grade B-cell Lymphoma (HGBCL), B-Cell Lymphoma Treatment, Relapsed or Refractory Lymphoma
DrugLoncastuximab Tesirine
Istituto Clinico Humanitas
Phase 2
50
Alessandria, Bologna, Cuneo, Milan, Rozzano, Roma
2023-06-16
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
306
Roma
2023-06-15
Active, closed
Ultragenyx Pharmaceutical Inc
Phase 3
69
Roma
2023-06-14
Active, closed
RHEACELL GmbH & Co. KG
Phase 3
91
Milan, Roma
2023-06-13
Recruiting
National Cancer Institute, Naples
Phase 2
240
Naples, Milan, Roma, Verona
2023-06-12
Active, closed
Evaluation of the Safety and Efficacy of Eneboparatide (AZP-3601) in Patients With Chronic Hypoparathyroidism
NCT05778071Chronic Hypoparathyroidism, Endocrine System Diseases, Parathyroid Diseases
Alexion Pharmaceuticals, Inc.
Phase 3
165
Bologna, Florence, Milan, Pisa, Roma
2023-06-07
Active, closed
Bristol-Myers Squibb
Phase 1/2
100
Rozzano, Siena, Bergamo, Roma
2023-06-06
Active, closed
ArriVent BioPharma, Inc.
Phase 3
398
Rozzano, Aviano, Roma, Bari, Meldola, Milan
2023-06-01
Recruiting
Innate srl
Not applicable
55
Brescia, Rozzano, Roma
2023-06-01
Active, closed
Amgen
Phase 3
509
Bergamo, Catanzaro, Genova, Meldola (FC), Orbassano, Roma
2023-05-31
Active, closed
Sarepta Therapeutics, Inc.
Phase 3
148
Genova, Milan, Roma
2023-05-31
Recruiting
Central Serous Chorioretinopathy and Micropulse Laser Treatment
NCT06346405Central Serous Chorioretinopathy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
36
Roma
2023-05-31
Recruiting
Pfizer
Phase 3
318
Rozzano, Roma, Catania, Milan
2023-05-20
Recruiting
Biomarkers for Monitoring Dementia Progression
NCT06855368Alzheimer Disease
IRCCS San Raffaele Roma
Observational
300
Roma, Sassari
2023-05-18
Recruiting
Fondazione Policlinico Universitario Campus Bio-Medico
Not applicable
155
Roma
2023-05-15
Recruiting
Novartis Pharmaceuticals
Phase 3
200
Brescia, Catania, Florence, Pavia, Roma, Naples
2023-05-11
Active, closed
Phase III Study of AK112 for NSCLC Patients
NCT06396065Non-Squamous Non-small Cell Lung Cancer
DrugsIvonescimab·Pemetrexed·Carboplatin
Summit Therapeutics
Phase 3
420
Milan, Parma, Roma, Rome
2023-05-04
Active, closed
Servier Affaires Médicales
Phase 3
299
Bologna, Florence, Milan, Naples, Reggio Emilia, Roma, Rozzano, San Giovanni Rotondo
2023-05-03
Active, closed
A Study to Learn How Well Dupilumab Works in Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis and the Side Effects it May Have
NCT05831176Eosinophilic Gastritis (EoG), Eosinophilic Duodenitis (EoD), Eosinophilic Gastrointestinal Disease (EGID), Eosinophilic Gastroenteritis
DrugDupilumab
Regeneron Pharmaceuticals
Phase 2
22
Rozzano, Palermo, Bari, Milan, Pisa, Roma, Rome
2023-05-03
Recruiting
Platform of Randomized Adaptive Clinical Trials in Critical Illness
NCT05440851Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
University Health Network, Toronto
Not applicable
6,250
Cona, Foggia, Milan, Legnano, Palermo, Roma, Sassari, Trento
2023-04-30
By invitation
An Open-label Study of XEN1101 in Epilepsy
NCT05718817Focal Epilepsy, Tonic-Clonic Seizures
DrugAzetukalner
Xenon Pharmaceuticals Inc.
Phase 3
880
Bologna, Chieti, Pisa, Roma
2023-04-25
Active, closed
Novartis Pharmaceuticals
Phase 3
288
Ancona, Cona, Padova, Pisa, Roma, Torino
2023-04-21
Recruiting
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NCT04124120Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
Weill Medical College of Cornell University
Not applicable
2,300
Bari, Bergamo, Brescia, Cotignola, Florence, Roma, Torino
2023-04-17
Active, closed
Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab
NCT05626855Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3, Spinal Muscular Atrophy Type 2, SMA
DrugApitegromab
Scholar Rock, Inc.
Phase 3
238
Genova, Messina, Milan, Roma
2023-04-17
Recruiting
Eli Lilly and Company
Phase 1/2
880
Alessandria, Brescia, Milan, Monza, Pisa, Ravenna, Roma, Verona
2023-04-17
Recruiting
University of Roma La Sapienza
Observational
150
Roma
2023-04-15
Active, closed
Umecrine Cognition AB
Phase 1/2
84
Milan, Padova, Palermo, Roma, Rozzano, Udine
2023-04-14
Active, closed
AstraZeneca
Phase 3
94
Milan, Roma
2023-04-05
Active, closed
GlaxoSmithKline
Phase 2
154
Milan, Padova, Roma
2023-04-03
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
300
Naples, Roma
2023-04-01
Active, closed
Bial R&D Investments, S.A.
Phase 2
237
Bologna, Brescia, Brindisi, Milan, Naples, Padova, Roma, Rozzano
2023-03-31
Active, closed
Janssen Research & Development, LLC
Phase 3
614
Bologna, Milan, Palermo, Pisa, Reggio Emilia, Roma, Siena, Turin
2023-03-29
Active, closed
Boston Scientific Corporation
Observational
1,173
Ancona, Mercogliano, Rivoli, Roma, Vicenza
2023-03-24
Recruiting
European Organisation for Research and Treatment of Cancer - EORTC
Observational
1,650
Bologna, Florence, Milan, Padova, Roma, Torino
2023-03-21
Active, closed
ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer
NCT05650879HER2 Mutant Non-small Cell Lung Cancer, HER2-positive Metastatic Breast Cancer, HER2 Gene Mutation, HER2 Amplification
DrugsELVN-002·Fam-Trastuzumab Deruxtecan-Nxki·Trastuzumab emtansine·Trastuzumab deruxtecan
Enliven Therapeutics
Phase 1
198
Monza, Candiolo, Aviano, Ancona, Roma, Rozzano
2023-03-20
Active, closed
Insmed Incorporated
Phase 2/3
91
Pavia, Monza, Palermo, Roma
2023-03-07
Active, closed
BeiGene
Phase 2
400
Roma, Verona
2023-03-07
Active, closed
Bristol-Myers Squibb
Phase 3
579
Genova, Siena, Bari, Milan, Naples, Perugia, Roma
2023-03-06
Recruiting
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
NCT05327062Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block
XSpline S.p.A.
Not applicable
150
Pavia, Roma, Bolzano, Rovereto
2023-03-06
Recruiting
Sentinel Lymph Node Biopsy in Ocular Surface and Adnexal Cancers
NCT05797415Ocular Sebaceous Carcinoma, Ocular Basal Cell Carcinoma, Ocular Surface Squamous Neoplasia, Merkel Cell Carcinoma, Unspecified
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
25
Roma
2023-03-01
Active, closed
Novartis Pharmaceuticals
Phase 2
33
Brescia, Florence, Genova, Milan, Roma
2023-02-28
Active, closed
AlgoTherapeutix
Phase 2
276
Campobasso, Meldola, Milan, Monza, Pavia, Roma
2023-02-28
Active, closed
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
NCT05566795Low-grade Glioma, Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma, Pediatric Low-grade Glioma
DrugsTovorafenib·Carboplatin
Day One Biopharmaceuticals, Inc.
Phase 3
418
Milan, Roma, Torino, Bari, Florence, Genova, Naples, Padova
2023-02-27
Active, closed
Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application
NCT05094089Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
W.L.Gore & Associates
Observational
320
Baggiovara, Naples, Roma
2023-02-24
Recruiting
Xenon Pharmaceuticals Inc.
Phase 3
160
Ancona, Chieti, Pisa, Roma
2023-02-14
Active, closed
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
NCT05685238Haemophilia A, Haemophilia A With Inhibitors
Novo Nordisk A/S
Phase 3
451
Rome, Florence, Milan, Naples, Roma, Torino
2023-02-13
Recruiting
Changes in Recipients Gut Microbiota After Fecal Microbiota Transplantation
NCT05739825Clostridioides Difficile Infection Recurrence
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
20
Roma
2023-02-13
Recruiting
Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation
NCT06813443Cardiomyopathies, Amyloidosis Cardiac, Fabry Disease, Arrhythmogenic Cardiomyopathy
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
700
Bologna, Roma, Florence
2023-02-13
Recruiting
Novartis Pharmaceuticals
Phase 3
195
Milan, Modena, Roma
2023-02-10
Active, closed
Novartis Pharmaceuticals
Phase 3
226
Bologna, Florence, Roma, Trieste, Vicenza
2023-02-03
Active, closed
Novartis Pharmaceuticals
Phase 3
152
Bologna, Roma, Trieste
2023-02-02
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
180
Roma
2023-01-30
Active, closed
Cenobamate in Adults With Focal-Onset Seizures
NCT05859854Epilepsy, Focal-Onset Seizure, Neurological Disorder
Aziende Chimiche Riunite Angelini Francesco S.p.A
Observational
936
Bari, Catanzaro, Pozzilli, Pavia, Roma, Torino, Conegliano, Udine
2023-01-24
Recruiting
Eli Lilly and Company
Phase 1
677
Milan, Roma
2023-01-12
By invitation
CT-evaluation of Coronary Ostia Height After Surgical Aortic Valve Replacement.
NCT05714293Heart Valve Diseases, Aortic Valve Stenosis, Aortic Valve Insufficiency, Regurgitation, Aortic
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
90
Roma
2023-01-11
Active, closed
Calcilytix Therapeutics, Inc., a BridgeBio company
Phase 3
67
Milan, Pisa, Roma
2023-01-06
Recruiting
Predicting Outcome of Cytoreduction in Advanced Ovarian Cancer
NCT06017557Ovarian Cancer Stage III, Ovarian Cancer Stage IV
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
151
Roma
2023-01-02
Active, closed
Phase 2b Study of GSK4532990 in Adults With NASH
NCT05583344Nonalcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver Disease
DrugGSK4532990
GlaxoSmithKline
Phase 2
284
Florence, Milan, Modena, Padova, Palermo, Roma, Rozzano MI, San Giovanni Rotondo FG
2023-01-02
Recruiting
IRCCS San Raffaele Roma
Observational
500
Roma
2023-01-01
Active, closed
Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)
NCT05024773Bladder Carcinoma in Situ (CIS)
Fidia Farmaceutici s.p.a.
Phase 3
130
Bergamo, Bologna, Castelfranco Veneto, Florence, Lecce, Milan, Naples, Roma
2022-12-29
By invitation
Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema
NCT05396105Hereditary Angioedema, Hereditary Angioedema Type I, Hereditary Angioedema Type II, Hereditary Angioedema Types I and II
DrugDeucrictibant
Pharvaris Netherlands B.V.
Phase 2/3
150
Catania, Milan, Naples, Padova, Palermo, Roma
2022-12-28
Active, closed
AriBio Co., Ltd.
Phase 3
1,535
Ancona, Brescia, Milan, Monza, Pisa, Roma, Torino, Tricase
2022-12-23
Active, closed
Novartis Pharmaceuticals
Phase 3
20
Roma
2022-12-19
Recruiting
H. Lundbeck A/S
Phase 1/2
42
Bologna, Roma
2022-12-19
Recruiting
Immunocore Ltd
Phase 3
540
Milan, Naples, Perugia, Roma, Siena
2022-12-19
Recruiting
Princess Maxima Center for Pediatric Oncology
Phase 3
160
Florence, Naples, Roma, Torino, Trieste, Verona
2022-12-15
Active, closed
Janssen Research & Development, LLC
Phase 3
213
Roma
2022-12-15
Recruiting
AstraZeneca
Phase 3
3,527
Arezzo, Brescia, Naples, Roma, Rozzano, Torino
2022-12-13
Recruiting
Pharming Technologies B.V.
Phase 2
180
Bologna, Messina, Milan, Pisa, Roma
2022-12-13
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
255
Roma
2022-12-09
Active, closed
PTC Therapeutics
Phase 3
130
Roma
2022-12-08
Active, closed
Novartis Pharmaceuticals
Phase 2
95
Bari, Rozzano, Roma, Orbassano
2022-12-06
By invitation
Ionis Pharmaceuticals, Inc.
Phase 3
1,400
Ancona, Florence, Padova, Pavia, Pisa, Roma
2022-11-30
Recruiting
ETOP IBCSG Partners Foundation
Phase 3
180
Naples, Padova, Perugia, Roma, Rome, Siena
2022-11-30
Active, closed
Mirati Therapeutics Inc.
Phase 2
90
Avellino, Casale Monferrato, Florence, Milan, Orbassano, Ravenna, Roma
2022-11-22
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 3
260
Bergamo, Brescia, Florence, Milan, Naples, Palermo, Pisa, Roma
2022-11-21
Active, closed
Novartis Pharmaceuticals
Phase 3
568
Meldola, Milan, Pisa, Roma, Torino
2022-11-21
Recruiting
Breast Cancer and Resilience in Couple
NCT06875414Breast Neoplasms, Quality of Life
Regina Elena Cancer Institute
Observational
40
Roma
2022-11-14
Active, closed
AstraZeneca
Phase 3
368
Bologna, Milan, Naples, Padova, Pisa, Roma, Rozzano, Verona
2022-11-10
Recruiting
Bayer
Phase 3
100
Bologna, Florence, Genova, Milan, Roma, Torino
2022-11-08
Active, closed
Agios Pharmaceuticals, Inc.
Phase 2
87
Milan, Pavia, Rozzano, Turin, Roma
2022-11-07
Recruiting
Effects of Nutrition on Post Stroke Fatigue
NCT05728229Fatigue, Stroke
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
120
Roma
2022-11-07
Active, closed
Novo Nordisk A/S
Phase 3
3,400
Bari, Catanzaro, San Donato Milanese (MI), Roma, Siena, Bologna, Catania, Padova
2022-11-01
Recruiting
Active Thoracic Compromised Distal LANding in TEvar
NCT06882967Thoracic Aortic Aneurysm, Aortic Diseases
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
200
Roma
2022-11-01
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 3
80
Avellino, Bassano del Grappa, Florence, Milan, Reggio Calabria, Roma
2022-10-28
Recruiting
Janssen Research & Development, LLC
Phase 3
1,590
Bergamo, Bologna, Florence, Milan, Naples, Pavia, Roma, Rozzano
2022-10-25
Active, closed
Almirall, S.A.
Phase 4
447
Arezzo, Brescia, Genova, Modena, Naples, Reggio Emilia, Roma, Rozzano
2022-10-24
Recruiting
Catholic University of the Sacred Heart
Not applicable
130
Roma
2022-10-10
Recruiting
PedAL BCU, LLC
Phase 3
130
Genova, Monza, Roma, Torino
2022-10-01
Recruiting
Ellipses Pharma
Phase 1/2
265
Aviano, Bologna, Milan, Roma, Torino
2022-09-30
Active, closed
Observational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency Disorder
NCT05373719Cyclin-Dependent Kinase-Like 5 Deficiency Disorder
Loulou Foundation
Observational
112
Florence, Roma, Rome, Verona
2022-09-30
Recruiting
Surgery for Male Stress Urinary Incontinence
NCT05771168Male Stress Urinary Incontinence
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
138
Roma
2022-09-29
Active, closed
A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease
NCT05347095Fistulizing Crohns Disease, Perianal Crohns Disease
DrugGuselkumab
Janssen-Cilag Ltd.
Phase 3
288
Milan, Negrar ( Ve), Pisa, Rho, Roma, Rozzano, San Giovanni Rotondo
2022-09-27
Recruiting
Janssen Research & Development, LLC
Phase 2/3
201
Catania, Genova, Milan, Naples, Orbassano, Pavia, Roma, Rozzano
2022-09-23
Active, closed
VisionCare, Inc.
Not applicable
68
Naples, Roma
2022-09-13
Active, closed
Biogen
Phase 2/3
450
Bologna, Brescia, Florence, Genova, Milan, Naples, Roma
2022-09-13
Active, closed
Redx Pharma Ltd
Phase 2
48
Ancona, Catania, Foggia, Lecce, Milan, Modena, Roma, Verona
2022-09-08
Recruiting
University of Milano Bicocca
Observational
500
Bari, Bologna, Brescia, Catania, Naples, Roma, Torino, Udine
2022-09-08
Recruiting
GlaxoSmithKline
Phase 3
109
Bologna, Catania, Milan, Naples, Novara, Pavia, Roma, Treviso
2022-09-06
By invitation
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease
NCT04905693Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Progressive Pulmonary Fibrosis
DrugTreprostinil
United Therapeutics
Phase 3
1,850
Modena, Rome, Milan, Catania, Siena, Ancona, Forlì, Roma
2022-09-06
By invitation
Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis
NCT04814693Acute Pancreatitis, Necrosis; Pancreas, Acute (Infectious)
Erasmus Medical Center
Not applicable
60
Milan, Roma
2022-09-02
Recruiting
phenotypeS in Non Ambulant Duchenne Muscular Dystrophy
NCT06366815Duchenne Muscular Dystrophy, Natural History, Motor Function; Retardation
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
250
Bosisio Parini, Roma
2022-08-30
Recruiting
Smith & Nephew, Inc.
Not applicable
234
Milan, Roma
2022-08-30
Recruiting
Asciminib Roll-over Study
NCT04877522Chronic Myelogenous Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive
DrugsAsciminib single agent·Bosutinib·ABL001·Nilotinib
Novartis Pharmaceuticals
Phase 4
347
Milan, Roma, Naples
2022-08-30
Recruiting
Acrivon Therapeutics
Phase 2
350
Aviano, Catania, Milan, Naples, Pieve Emanuele, Roma, Turin
2022-08-29
Active, closed
Madrigal Pharmaceuticals, Inc.
Phase 3
845
San Giovanni Rotondo, Milan, Rozzano, Roma, Torino, Florence, Palermo, Pisa
2022-08-26
Active, closed
Biogen
Phase 2
416
Tricase, Cefalù, Arzignano VI, Brescia, Milan, Perugia, Roma
2022-08-24
Active, closed
Gilead Sciences
Phase 2/3
689
Milan, Modena, Roma, Torino
2022-08-16
Active, closed
AstraZeneca
Phase 2
194
Candiolo, Milan, Naples, Padova, Perugia, Roma, Siena
2022-08-11
Active, closed
Novo Nordisk A/S
Phase 3
412
Milan, Florence, Genova, Naples, Roma, Rome
2022-08-10
Active, closed
Janssen Research & Development, LLC
Phase 3
418
Bari, Bologna, Milan, Orbassano, Padova, Ravenna, Roma, Rome
2022-08-05
Recruiting
Perpetual Observational Study - Ventilator Associated Pneumonia
NCT05719259Ventilator Associated Pneumonia
European Clinical Research Alliance for Infectious Diseases (ECRAID)
Observational
20,000
Roma
2022-08-03
Recruiting
IRCCS Burlo Garofolo
Observational
250
Monza, Roma, Torino, Trieste
2022-07-30
Recruiting
Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse
Not applicable
164
Roma
2022-07-29
Recruiting
Research Maatschap Cardiologen Rotterdam Zuid
Phase 4
1,656
Bergamo, Ferrara, Genova, Milan, Naples, Roma
2022-07-22
Active, closed
A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)
NCT05458297Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Follicular Lymphoma, Richter Transformation Lymphoma
DrugsZilovertamab vedotin·Nemtabrutinib
Merck Sharp & Dohme LLC
Phase 2
189
Bologna, Rozzano, Alessandria, Roma
2022-07-21
Active, closed
GlaxoSmithKline
Phase 3
163
Bari, Brescia, Florence, Milan, Pavia, Pisa, Roma, Torrette AN
2022-07-14
Recruiting
Fondazione Italiana Linfomi - ETS
Phase 2
28
Ancona, Aviano, Florence, Miano, Monza, Naples, Roma, Palermo
2022-07-11
Active, closed
Daiichi Sankyo
Phase 3
586
Bari, Chieti, Lucca, Milan, Orbassano, Parma, Perugia, Roma
2022-07-08
Active, closed
Biohaven Pharmaceuticals, Inc.
Phase 3
269
Bologna, Gussago, Pavia, Roma
2022-07-06
Recruiting
AIOCC Italian Registry on Head and Neck Carcinomas
NCT06248944Head and Neck Carcinoma
Italian Head&Neck Society
Observational
7,000
Candiolo, Florence, Lecce, Milan, Pavia, Roma, Verona
2022-07-06
Active, closed
Janssen Research & Development, LLC
Phase 2
36
Ancona, Milan, Pavia, Roma
2022-07-05
Recruiting
Octapharma
Phase 3
38
Bergamo, Milan, Padua, Roma
2022-07-01
Recruiting
Azienda Ospedaliera di Padova
Observational
46
Bologna, Brescia, Florence, Genova, Padova, Roma
2022-07-01
Active, closed
AstraZeneca
Phase 3
53
Messina, Naples, Roma
2022-07-01
Recruiting
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry
NCT05430971Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Immune Oncology Research Institute
Observational
200
Perugia, Roma
2022-07-01
Active, closed
Corcept Therapeutics
Phase 3
381
Catania, Legnago, Milan, Pavia, Roma, Rome, Torino, Treviso
2022-06-29
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 2/3
12
Chieti, Gallarate, Roma
2022-06-23
Recruiting
CytOSorb TreatMent Of Critically Ill PatientS Registry
NCT05146336Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
CytoSorbents, Inc
Observational
3,000
Roma, San Giovanni Rotondo
2022-06-22
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
150
Roma
2022-06-20
Recruiting
Priothera SAS
Phase 3
366
Brindisi, Reggio Calabria, San Giovanni Rotondo, Lecce, Roma, Alessandria, Ascoli Piceno, Florence
2022-06-16
Active, closed
Novartis Pharmaceuticals
Phase 3
95
Lucca, Aviano, Roma
2022-06-15
Active, closed
RECORDATI GROUP
Observational
206
Ancona, Milan, Naples, Roma
2022-06-13
Recruiting
Evaluation of Collagen-based Medical Device Treatment Combined With Physiotherapy in Subjects With Achilles Tendinopathy.
NCT05464498Tendinopathy, Insertional Achilles Tendinopathy, Achilles Tendinopathy, Peritendinitis
Guna S.p.a
Not applicable
72
Roma
2022-06-13
By invitation
Biogen
Phase 3
864
Roma
2022-06-10
Recruiting
The Head and Neck Registry of the European Reference Network on Rare Adult Solid Cancers
NCT05483374Head and Neck Cancer, Nasopharynx Cancer, Nasal Cavity and Paranasal Sinus Cancer, Salivary Gland Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
13,600
Genova, Milan, Rozzano, Pavia, Prato, Roma
2022-05-31
Recruiting
CardioPulmonary Resuscitation With Argon (CPAr) Trial
NCT05482945Cardiac Arrest, Out-Of-Hospital, Cardiac Arrest With Successful Resuscitation
Mario Negri Institute for Pharmacological Research
Phase 2
120
Genova, Monza, Milan, Parma, Pordenone, Reggio Emilia, Roma, Trento
2022-05-30
Recruiting
Dimerix Bioscience Pty Ltd
Phase 3
286
Bari, Bologna, Genova, Milan, Pavia, Roma, Torino
2022-05-30
Recruiting
Gruppo Oncologico Italiano di Ricerca Clinica
Phase 2
49
Bologna, Viagrande, Meldola, Florence, Rozzano, Padova, Aviano, Roma
2022-05-27
Active, closed
PASS of Paediatric Patients Initiating Selumetinib
NCT05388370Neurofibromatosis Type 1
AstraZeneca
Observational
124
Florence, Genova, Milan, Padova, Pavia, Roma, Torino, Trieste
2022-05-23
Recruiting
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
NCT06031025Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
71
Roma
2022-05-20
Recruiting
National Cancer Institute, Naples
Observational
300
Naples, Roma
2022-05-19
Recruiting
Electra Therapeutics Inc.
Phase 2/3
156
Florence, Genova, Milan, Monza, Padova, Roma, Trieste
2022-05-19
Recruiting
Centervue SpA
Observational
200
Milan, Roma
2022-05-06
Recruiting
Type 2 Diabetes, Obesity and Cortisol Excess
NCT05759637Diabetes Mellitus, Type 2, Obesity, Cortisol; Hypersecretion
Istituto Auxologico Italiano
Observational
3,200
Milan, Roma, Siena, Udine
2022-05-06
Recruiting
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
372
Milan, Aviano, Roma, Padova, Pisa, Terni
2022-05-03
Recruiting
Fondazione Ricerca Traslazionale
Phase 2
176
Roma
2022-05-02
Recruiting
UNICANCER
Phase 3
300
Bari, Candiolo, Foggia, Meldola, Milan, Naples, Roma, Rozzano
2022-04-19
Active, closed
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 2
154
Turin, Florence, Genova, Milan, Pavia, Reggio Emilia, Roma
2022-03-29
Active, closed
AstraZeneca
Phase 3
760
Arezzo, Florence, Milan, Roma, Rozzano, Tricase
2022-03-28
Active, closed
Bayer
Phase 3
219
Bologna, Florence, Genova, Milan, Roma, Torino
2022-03-28
Active, closed
MaaT013 As Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients
NCT04769895Acute Graft Versus Host Disease in Intestine, Steroid Refractory GVHD
MaaT Pharma
Phase 3
66
Ancona, Bologna, Genova, Milan, Reggio Calabria, Roma, Torino, Udine
2022-03-25
Active, closed
Pfizer
Phase 3
854
Meldola, Rome, Milan, Catania, Siena, Ancona, Bologna, Roma
2022-03-25
Active, closed
W.L.Gore & Associates
Observational
259
Genova, Milan, Roma
2022-03-23
Recruiting
Amgen
Phase 3
60
Chieti, Genova, Milan, Roma
2022-03-17
Active, closed
Sanofi
Phase 3
122
Bologna, Monza, Naples, Palermo, Roma
2022-03-11
Active, closed
A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.
NCT05064878CDKL5 Deficiency Disorder, Generalized Tonic Clonic Seizure, Epileptic Spasm, Refractory Seizures
DrugFintepla
Zogenix, Inc.
Phase 3
87
Florence, Genova, Modena, Roma, Verona
2022-03-08
Recruiting
Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients
NCT06309251Drug Resistant Epilepsy, Autism Spectrum Disorder, Chronic Migraine, Brain Tumor, Pediatric
Danone Nutricia SpA Società Benefit
Observational
100
Milan, Pavia, Roma
2022-03-01
Active, closed
Janssen Research & Development, LLC
Phase 2
151
Naples, Pavia, Roma
2022-03-01
Active, closed
I.R.C.C.S. Fondazione Santa Lucia
Not applicable
24
Roma
2022-03-01
Active, closed
AstraZeneca
Phase 3
791
Bergamo, Roma, Rozzano
2022-02-18
Active, closed
AstraZeneca
Phase 3
363
Ancona, Cona, Eboli, Padova, Roma
2022-02-15
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
92
Roma
2022-02-15
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
200
Roma
2022-02-10
Active, closed
AstraZeneca
Phase 3
1,051
Brescia, Florence, Lucca, Meldola, Orbassano, Parma, Pavia, Roma
2022-02-07
By invitation
UCB Biopharma SRL
Phase 3
300
Genova, Milan, Pavia, Roma
2022-02-03
Active, closed
UCB Biopharma SRL
Phase 3
113
Pavia, Roma, Verona
2022-02-02
Active, closed
Fondazione G.B. Bietti, IRCCS
Not applicable
29
Roma, Rome
2022-01-25
Active, closed
Biogen
Phase 3
45
Milan, Roma, Torino
2022-01-21
Active, closed
Janssen Research & Development, LLC
Phase 3
350
Bologna, Milan, Roma
2022-01-19
Active, closed
A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
NCT05002127Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma
DrugsEvorpacept·Ramucirumab·Herceptin·Taxol
ALX Oncology Inc.
Phase 2/3
127
Catania, Florence, Milan, Roma, Udine
2022-01-15
Recruiting
Merck Sharp & Dohme LLC
Phase 2/3
290
Rozzano, Bologna, Naples, Roma
2022-01-14
Active, closed
Società Italiana Talassemie ed Emoglobinopatie
Observational
1,000
Torino, Cagliari, Ferrara, Genova, Milan, Naples, Palermo, Roma
2022-01-01
Recruiting
Novartis Pharmaceuticals
Phase 1/2
34
Genova, Monza, Roma, Torino
2021-12-27
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
35
Roma
2021-12-23
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
35
Roma
2021-12-23
Recruiting
Occlutech International AB
Observational
255
Roma
2021-12-20
Active, closed
Novartis Pharmaceuticals
Phase 3
1,000
Milan, Roma, Verona, Novara
2021-12-16
Recruiting
Takeda
Phase 2
135
Bari, Bologna, Brescia, Florence, Genova, Milan, Reggio Emilia, Roma
2021-12-16
Active, closed
Regeneron Pharmaceuticals
Phase 3
288
Rome, Milan, Pisa, Bergamo, Roma
2021-12-14
Active, closed
NATURE (EnVast as an Adjunct PPCI in Subjects Presenting With STEMI)
NCT04969471Segment Elevation Myocardial Infarction (STEMI)
Vesalio
Not applicable
148
Ferrara, Milan, Roma
2021-12-09
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
54
Roma
2021-12-07
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Italian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 11 October 2026. https://priyalifescience.com/clinical-trials-italy/city/roma?page=2

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Italy and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,778 studies in total at the last sync on 08 Oct 2026, 03:19 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 1,274 of those studies with a site in Roma.

How many clinical trials are recruiting in Roma?

716 of the 1,274 studies on this page are recruiting new participants as of the 08 Oct 2026, 03:19 UTC sync. A further 94 have not yet opened recruitment, 438 are active but closed to new participants, and 26 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.