Perpetual Observational Study - Ventilator Associated Pneumonia

Condition(s) studied

Study summary

Ventilator-Associated Pneumonia (VAP) is a bacterial respiratory infection that patients in the Intensive Care Unit (ICU) often get when they cannot breathe for themselves and require mechanical ventilation. It is linked to higher chances of death, a longer stay in the hospital, higher costs, and the use of more antibiotics.

Options to help prevent or treat this disease are in development and will require evaluation in future clinical trials.

The goal of POS-VAP is to build and continuously train a network of ICUs to be prepared for doing these trials, to facilitate their execution.

Eligibility

Primary outcome measure(s)

• Number of research sites recruiting patients — 4 years
  POS-VAP' overarching objective is to build a sustainable European clinical research network of ICUs that serves as platform to facilitate observational and randomized VAP research activities. This objective will be measured by in three ways: 1\. Total number of sites in the POS-VAP network that actively recruit patients
• Number of patients recruited in the study — 4 years
  2\. Total number of patients in the POS-VAP network per analysis population (enrolled population, VAP population and microbiologically evaluable VAP population).
• Number of studies implemented through the network — 4 years
  3\. Total number of implemented observational studies and RCTs (stratified by domain: prevention, diagnosis and treatment).

Trial sites (35)