Clinical trial register · China

Clinical Trials in China

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 19187 matching records held by the registry are in this view. Synced 07 Nov 2026, 03:17 UTC

19187

Studies in scope

all four open statuses

11790

Recruiting now

open to new participants

2028

Lead sponsors

across recruiting studies

Top sites

Beijing 5576 Shanghai 3879 Guangzhou 3345 Hangzhou 1819 Wuhan 1343

Trials in this register

Status

Study

Lead sponsor

Phase

Enrol

Chinese sites

Start

Recruiting

Radiotherapy Followed by Tiselizumab Combined With RCHOP in Previously Untreated Bulky Follicular Lymphoma

NCT06704555Follicular Lymphoma

DrugsVincristine·Doxorubicin·Prednisone·Rituximab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-12-20

Recruiting

Ophthalmic Multimodal AI-Assisted Medical Decision-Making

NCT06755190Ocular Diseases

The Eye Hospital of Wenzhou Medical University

Observational

5,000,000

Zhuhai, Wenzhou

2024-12-20

Recruiting

Removable Titanium Clip Treatment for Acute Variceal Hemorrhage from the Gastric Fundus

NCT06736314Gastric Variceal Bleeding

Shupei Li

Not applicable

Nanjing

2024-12-20

Recruiting

Targeting NUDT21 siRNA Drugs for Patients With Refractory Retinoblastoma

NCT06424301Retinoblastoma, Refractory

Eye & ENT Hospital of Fudan University

Early Phase 1

Shanghai

2024-12-20

Active, closed

A Phase IIb Study of 610 in Participants With Severe Eosinophilic Asthma

NCT06680947Asthma

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

Phase 2

225

Shanghai

2024-12-20

Not yet open

An Exploratory Clinical Study Evaluating EPI-003 Injection for the Treatment of Chronic Hepatitis B

NCT06745973Chronic Hepatitis B

DrugEPI-003

Epigenic Therapeutics, Inc

Early Phase 1

Shanghai

2024-12-20

Recruiting

A Study of GC101 TIL in Advanced Melanoma

NCT06703398Melanoma

DrugsAutologous Tumor Infiltrating Lymphocytes·Cisplatin

Shanghai Juncell Therapeutics

Phase 2

Beijing

2024-12-20

Not yet open

Chidamide Combined With Angiogenesis Inhibitors and Fulvestrant for Advanced HR-positive, HER2-negative Breast Cancer

NCT06750848Advanced Breast Cancer

Jundong Wu

Phase 2

Shantou

2024-12-20

Not yet open

TAES Alleviate Post-VATS Depression

NCT06718231Depression After Video-assisted Thoracoscopic Surgery

Fuling Central Hospital of Chongqing City

Not applicable

120

Fuling

2024-12-20

Recruiting

The Optimal Radioimmunotherapy Combinations for Advanced TNBC

NCT06735131Triple-Negative Breast Cancer (TNBC)

DrugToripalimab

Sun Yat-sen University

Phase 2

Guangzhou

2024-12-20

Recruiting

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

NCT06500702Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion

DrugsBrivekimig·Frexalimab·Rilzabrutinib

Sanofi

Phase 2

Beijing, Chengdu, Shanghai

2024-12-19

Recruiting

Head-to-head Comparison of [18F]AlF-PSMA-N5 With [18F]F-DCFPyL PET/CT in PCa Diagnosis, Recurrence, and Metastasis

NCT06756334Prostate Cancer, PET/CT

Anhui Provincial Hospital

Early Phase 1

Hefei

2024-12-19

Recruiting

Safety and Efficacy of NRG-103 Injection in the Treatment of Recurrent Glioblastoma Patients

NCT06757153Glioblastoma (GBM)

DrugNRG-103

Zhongnan Hospital

Early Phase 1

Wuhan

2024-12-19

Active, closed

A Study of JNJ-87562761 in Participants With Relapsed or Refractory Multiple Myeloma

NCT06604715Relapsed or Refractory Multiple Myeloma

Janssen Research & Development, LLC

Phase 1

2024-12-19

Recruiting

Spatially Fractionated Radiotherapy for Tumor Treatment

NCT07774819Radiotherapy-Induced Immune Priming

Xu Zhi-yuan

Phase 1/2

126

Shenzhen

2024-12-19

Active, closed

Efficacy and Safety of OsrhCT and Dimethicone Emulsion Before Upper Endoscopy on Visualization of the Gastric Mucosa.

NCT06722664Gastric Mucosal Lesion

DrugDimethicone

Healthgen Biotechnology Corp.

Phase 2

336

Beijing, Wuhan, Hohhot

2024-12-19

Recruiting

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

NCT06736574Heart Failure, Heart Failure With Reduced Ejection Fraction

Cytokinetics

Phase 3

1,800

Beijing, Chongqing, Lanzhou, Guangzhou, Shenzhen, Nanning, Harbin, Luoyang

2024-12-19

Recruiting

Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement

NCT06766630Rotator Cuff Tear

Weiliang Shen, Ph.D., M.D.

Phase 2/3

Hangzhou

2024-12-19

Active, closed

A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy

NCT06742190Multifocal Motor Neuropathy (MMN), MMN

DrugsEmpasiprubart·Immunoglobulin·IVIG

argenx

Phase 3

154

Shanghai

2024-12-18

Recruiting

Phase I Study of HSK46575 in Patients With Metastatic Castration-Resistant Prostate Cancer

NCT07007910m CRPC

Haisco Pharmaceutical Group Co., Ltd.

Phase 1

Chengdu

2024-12-18

Recruiting

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

NCT06656494Acute Myelogenous Leukemia, Myelodysplastic Syndromes (MDS)

DrugsICP-248·Azacitidine

Beijing InnoCare Pharma Tech Co., Ltd.

Phase 1

266

Hefei, Beijing, Chongqing, Guangzhou, Zhengzhou, Wuhan, Suzhou, Nanchang

2024-12-18

Recruiting

Validation of the Accuracy of a Novel POCT Dry Electrolyte Analysis System in the Acute Care Setting

NCT06726460Electrolyte Disorder, Arrhythmia, Stroke

Zhujiang Hospital

Observational

200

Guangzhou

2024-12-17

Recruiting

A Phase 1 Study of SKB571 in Subjects With Advanced Solid Tumors

NCT06725381Solid Malignancies

DrugSKB571

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Phase 1

138

Guangzhou, Nanning, Wuhan, Changsha, Nanjing, Jinan, Linyi, Chengdu

2024-12-17

Recruiting

APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST

NCT06687070Platinum-resistant Recurrent Ovarian Cancer, Advanced Solid Tumor

DrugAPG -2449

Ascentage Pharma Group Inc.

Phase 1

Guangzhou

2024-12-17

Recruiting

Multicenter Phase I Study of HRS-6208 in Patients With Solid Tumors

NCT06727812Solid Tumors

DrugHRS-6208

Shandong Suncadia Medicine Co., Ltd.

Phase 1

206

Nanjing, Chengdu

2024-12-17

Active, closed

A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer (TAISHAN-302)

NCT06612151Small Cell Lung Cancer

DrugsTam-Peli·Topotecan

MediLink Therapeutics (Suzhou) Co., Ltd.

Phase 3

438

Guangzhou

2024-12-17

Recruiting

Integrative Analysis of Exosome-Mediated Single-Cell Transcriptomics and Proteomics in Gastric Cardia Cancer

NCT06702891Gastric Cardia Cancer

Qilu Hospital of Shandong University

Observational

Jinan

2024-12-17

Recruiting

High-Voltage Long-Duration Pulsed Radiofrequency Combined With Liposomal Bupivacaine Subcutaneous Block for Herpes Zoster-Associated Neuralgia

NCT06959147Herpes Zoster Pain, Neuralgia, Postherpetic

Shirong Tan

Phase 4

Zunyi

2024-12-17

Recruiting

Assessment of the Predictive Value of Anti-beta1AR and Anti-L-CaC Antibodies in the Evolution to Dilated Cardiomyopathy in Patients With Acute Viral Myocarditis

NCT06742008Viral Myocarditis

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

300

Wuhan

2024-12-17

Recruiting

Evaluating the Prognostic Impact of Anti-β1AR Antibodies and Anti-L-CaC Antibodies in Patients With Dilated Cardiomyopathy

NCT06741995Dilated Cardiomyopathy (DCM)

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

1,000

Wuhan

2024-12-17

Not yet open

Aumolertinib Versus Osimertinib As First-line Therapy for Patients with EGFR Mutated Locally Advanced or Metastatic Non-small-cell Lung Cancer

NCT06752408Non Small Cell Lung Cancer

DrugsAlmonertinib·Osimertinib

Peking Union Medical College Hospital

Phase 2

316

Beijing

2024-12-17

Not yet open

Efficacy and Safety of Intravenous + Oral Vs. Oral Amiodarone in Preventing Recurrence After Catheter Ablation in Patients with Persistent Atrial Fibrillation

NCT06742866Atrial Fibrillation (AF)

DrugAmiodarone

Shanghai Chest Hospital

Not applicable

418

Shanghai

2024-12-16

Recruiting

Intrathecal Morphine for Postoperative Analgesia in Major Laparoscopic Abdominal Surgery, a IMPACT-Scope Trial

NCT06666985Patients Undergoing Major Laparoscopic Abdominal Surgery

First Affiliated Hospital, Sun Yat-Sen University

Phase 4

700

Guangzhou

2024-12-16

Recruiting

Comparing Endoscopic Strictureplasty vs. Balloon Dilation in Crohn's Disease Strictures

NCT06203782Crohn Disease

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

102

Hangzhou

2024-12-16

Recruiting

Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS)

NCT06738758Acute Coronary Syndromes

DrugBiweekly

Yun Dai Chen

Observational

6,000

Beijing

2024-12-16

By invitation

Non-invasive Methods for Predicting Decompensation of Chronic Liver Disease

NCT06741904Chronic Liver Disease and Cirrhosis

Nanfang Hospital, Southern Medical University

Observational

2,334

Guangzhou

2024-12-16

Recruiting

A Multicenter, Randomized Controlled Clinical Investigation to Evaluate the Safety and Effectiveness of the Super-Bore 8/7F Aspiration Catheters in the Treatment of Acute Intracranial Large Vessel Occlusion

NCT06559475Acute Ischemic Stroke, Endovascular Thrombectomy

The First Affiliated Hospital of University of Science and Technology of China

Not applicable

360

Hefei

2024-12-16

Recruiting

Study on the Mechanism of Cognitive Impairment in Patients with Moyamoya Disease

NCT06832839Moyamoya Disease

Beijing Tiantan Hospital

Observational

360

Beijing

2024-12-16

Recruiting

Efficacy of Extended Letermovir Prophylaxis to Prevent CMV Reactivation in High-Risk Chinese Adults Undergoing Allogeneic HSCT

NCT06812598Cytomegalovirus Infections, CMV

The First Affiliated Hospital of Soochow University

Not applicable

330

Suzhou

2024-12-16

Recruiting

Study of BM230 in Patients With Advanced Solid Tumors

NCT06644300Solid Tumor

Suzhou Biomissile Pharmaceuticals Co., Ltd.

Phase 1

123

Bengbu, Shanghai, Hangzhou

2024-12-16

Not yet open

Atrial Fibrillation with Heart Failure with Preserved Ejection Fraction: Treatment Strategies-Catheter Ablation Vs. Anti-Atrial Arrhythmia Drugs

NCT06740539HFpEF - Heart Failure with Preserved Ejection Fraction, Atrial Fibrillation (AF)

Shanghai Chest Hospital

Not applicable

304

Shanghai

2024-12-16

Recruiting

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

NCT06679101Multiple Myeloma, Newly Diagnosed Multiple Myeloma

DrugsBelantamab mafodotin·Daratumumab·Lenalidomide·Dexamethasone

GlaxoSmithKline

Phase 3

520

Beijing, Chengdu, Chongqing, Guangzhou, Hangzhou, Nanchang, Nanjing, Shanghai

2024-12-16

Recruiting

Using Mukbang to Improve Appetite, Nutritional Status and Quality of Life in Children With Cancer

NCT05922553Children With Cancer

Wei XIA, PhD

Not applicable

124

Guangzhou

2024-12-16

Recruiting

An Intervention Study on Transcranial Photobiomodulation in Children With Attention Deficit Hyperactivity Disorder

NCT06685601ADHD - Attention Deficit Disorder With Hyperactivity

Qilu Hospital of Shandong University

Not applicable

Jinan

2024-12-16

Recruiting

Clinical Study on the Treatment of Herpes Zoster Pain With Dexmedetomidine Combined With Long-term High Voltage

NCT06978192Herpes Zoster (HZ)

Fenghui Deng

Phase 2

Zunyi

2024-12-16

Active, closed

A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer

NCT06747338Early or Locally Advanced HER2-positive Breast Cancer

DrugsKN026·Pertuzumab·Trastuzumab·Docetaxel

Shanghai JMT-Bio Inc.

Phase 3

520

Shanghai

2024-12-16

Recruiting

Long-term Follow-up Registry Study of Equecabtagene Autoleucel Injection

NCT07028970Multiple Myeloma

Nanjing IASO Biotechnology Co., Ltd.

Observational

1,500

Beijing, Tianjin, Wuhan, Zhengzhou

2024-12-15

Recruiting

Evaluation of a CAM System for Colorectal Polyp Size Measurement

NCT06715384Colorectal Polyp, Colorectal Adenoma

Changhai Hospital

Not applicable

168

Shanghai

2024-12-15

Recruiting

A Randomized Trial Comparing the Efficacy and Safety of Secukinumab with Tofacitinib in the Treatment of Moderate to Severe Hidradenitis Suppurativa in Chinese Patients

NCT06707246Hidradenitis Suppurativa

DrugsSecukinumab·Tofacitinib

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

Hangzhou

2024-12-15

By invitation

INK Cells As Maintenance Therapy After Chemoradiotherapy for Small Cell Lung Cancer

NCT06747832Small Cell Lung Cancer

Guangzhou Ruixin Biotechnological Co., LTD

Early Phase 1

Weifang

2024-12-15

Recruiting

Effects of Transcranial Electrical Stimulation on Cognitive Impairment in CNS Inflammatory Demyelinating Diseases

NCT07029386Idiopathic Inflammatory Demyelinating Disorders of the Central Nervous System

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-12-15

Recruiting

Clinical Study of IM96 CAR-T Cell Therapy in Patients With Advanced Colorectal Cancer

NCT06718738Colorectal Cancer (CRC)

Beijing Immunochina Medical Science & Technology Co., Ltd.

Phase 1

Beijing

2024-12-15

Active, closed

Tirellizumab Combined With TP Neoadjuvant Therapy in the Treatment of Early Oral Squamous Cell Carcinoma （HNC-SYSU-005）

NCT07267286HNSCC, PD-1

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase 2

Guangzhou

2024-12-15

Not yet open

Construction of a Risk Screening Tool for New Psychoactive Substance Misuse Among Adolescents and Young Adults

NCT06714578Drug Misuse, Addiction

Wei XIA, PhD

Observational

1,035

Guangzhou

2024-12-15

Recruiting

fNIRS-Driven Visual Feedback Training to Restore Walking After Stroke

NCT07014891Stroke

Shengjing Hospital

Not applicable

Shenyang

2024-12-15

Not yet open

A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC

NCT06690671Lung Cancer, Non-Small Cell

DrugsAnti-PD-1·Golidocitinib

Shanghai Chest Hospital

Phase 1/2

Shanghai

2024-12-15

Recruiting

Study on Evaluating the Effectiveness of Statins in the Treatment of Moyamoya Disease

NCT06817434Moyamoya Disease

Beijing Tiantan Hospital

Observational

330

Beijing

2024-12-15

Recruiting

Double Pig Tail Stent-assisted Fixation of Fully Covered Metal Stents for the Treatment of Benign Duodenal Strictures

NCT06736301Benign Duodenal Stricture

Shupei Li

Not applicable

Nanjing

2024-12-15

Recruiting

Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors

NCT06621563Solid Tumors, Non-Small Cell Lung Cancer, Colorectal Cancer

DrugsHS-20117·Capeox·MFOLFOX6·Folfox

Hansoh BioMedical R&D Company

Phase 1

780

Tianjin

2024-12-14

Recruiting

Efficacy and Influencing Factors of ALIC-NAc Deep Brain Stimulation in Treatment-Refractory Obsessive-Compulsive Disorder

NCT07031544Obsessive - Compulsive Disorder

Shanghai Mental Health Center

Not applicable

Guangzhou, Shijiazhuang, Xinxiang, Nanchang, Taiyuan, Mianyang, Shanghai, Tianjin

2024-12-14

Recruiting

Universal CNK-UT Therapy for Refractory aGVHD

NCT06750133Acute Graft-versus-Host Disease

First Affiliated Hospital of Zhejiang University

Phase 1

Fuzhou, Hangzhou

2024-12-14

Active, closed

A Study to Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

NCT06628310Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Esophageal Adenocarcinoma

DrugsBudigalimab·Telisotuzumab Adizutecan·Fluorouracil·Leucovorin

AbbVie

Phase 2

185

Beijing, Langfang, Harbin, Wuhan, Hangzhou

2024-12-13

Recruiting

TACE Combined With Lenvatinib and PD-1 Inhibitor for Ruptured Hepatocellular Carcinoma

NCT06740370Hepatocellular Carcinoma, Transcatheter Arterial Chemoembolization, Anti-PD1 Antibody, Lenvatinib

DrugsVenetocalx·Lenvatinib

Sun Yat-sen University

Not applicable

Beijing

2024-12-13

Recruiting

A Study on the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of SKB500 in Subjects With Advanced Solid Tumors

NCT06736327Advanced Solid Tumors

DrugSKB500

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Phase 1

180

Jilin City

2024-12-13

Active, closed

Study to Evaluate the Efficacy and Safety of AHB-137 in Treatment-naive Participants With Chronic Hepatitis B (CHB)

NCT06829329Chronic Hepatitis B

DrugAHB-137

Ausper Biopharma Co., Ltd.

Phase 2

105

Chongqing, Fuzhou, Guangzhou, Changzhou, Zhenjiang, Hangzhou

2024-12-13

Recruiting

Efficacy, Safety, and Immunogenicity of the Bivalent Inactivated Enterovirus Vaccine (Vero Cell)

NCT06734832Hand, Foot, and Mouth Disease（HFMD)

Sinovac Biotech Co., Ltd

Phase 3

8,000

Hefei, Fujian, Guangdong, Hubei

2024-12-13

Recruiting

Remote Anxiety Management for ICS-resistant Asthma Study

NCT06732141Asthma

First Affiliated Hospital of Ningbo University

Not applicable

216

Harbin, Hefei, Jingzhou, Ningbo, Ninghai, Taizhou

2024-12-13

Active, closed

Study to Evaluate the Efficacy and Safety of VGR-R01 Gene Therapy in Patients With Bietti Crystalline Dystrophy

NCT06699108Bietti Crystalline Dystrophy, Inherited Retinal Diseases

DrugVGR-R01

Shanghai Vitalgen BioPharma Co., Ltd.

Phase 3

Shanghai

2024-12-13

Recruiting

Normobaric Oxygen in AIS Transferred for EVT

NCT06666764Ischemic Stroke

Capital Medical University

Phase 3

1,500

Beijing, Fuzhou, Ningde, Putian, Zhangzhou, Guangzhou, Hezhou, Cangzhou

2024-12-13

Recruiting

Clinical Trial of HG146 Administered to Participants With Adenoid Cystic Carcinoma

NCT06781567Adenoid Cystic Carcinoma, Head and Neck Cancer

HitGen Inc.

Phase 2

140

Shanghai

2024-12-13

Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

NCT06750094Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Avastin

Janssen Research & Development, LLC

Phase 3

700

Beijing, Changchun, Changsha, Chengdu, Ganzhou, Guangzhou, Hangzhou, Harbin

2024-12-12

Recruiting

A Clinical Trial of CEA Targeting CAR-T for CEA Positive Advanced Lung Cancer

NCT06768151Advanced Lung Cancer

DrugTargeted CEA CAR-T

Chongqing Precision Biotech Co., Ltd

Phase 1

Wuhan

2024-12-12

Recruiting

Clinical Trial of CD123-targeted CAR-NK Therapy for Relapse/Refractory AML or BPDCN

NCT06690827AML (Acute Myeloid Leukemia), BPDCN (Blastic Plasmacytoid Dendritic Cell Neoplasm)

Chongqing Precision Biotech Co., Ltd

Phase 1

Wuhan

2024-12-12

Recruiting

A Study of Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer

NCT06686576Colon Cancer

DrugLenvatinib

Qilu Pharmaceutical Co., Ltd.

Phase 3

363

Guangzhou

2024-12-12

Recruiting

Inhaled Nitric Oxide for the Treatment of Neonatal Hypoxic Respiratory Failure With Pulmonary Hypertension

NCT07099144Pulmonary Hypertension, Hypoxic Respiratory Failure

DrugNitric Oxide

Lee's Pharmaceutical Limited

Observational

120

Guangzhou

2024-12-12

Recruiting

A Study of SIGX1094R in Patients With Advanced Solid Tumors

NCT06739291Advanced Solid Tumors

Signet Therapeutics

Phase 1

102

Beijing

2024-12-12

Recruiting

TEOSYAL RHA® 1 for the Correction of Moderate to Severe Tissue Volume Deficiency in the Infraorbital Region in Chinese Adults

NCT06749587Infraorbital Hollows

Teoxane SA

Not applicable

260

Guangzhou

2024-12-12

Recruiting

A Randomized Trial of Imaging Selection Modalities for Stroke Thrombectomy (NO-SELECT)

NCT05230914Stroke, Ischemic, Stroke, Acute

Xinqiao Hospital of Chongqing

Not applicable

1,846

Wuhu, Chongqing, Jiangmen, Haikou, Huai'an, Wuxi, Jingdezhen, Dalian

2024-12-12

Recruiting

A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed/ Refractory Multiple Myeloma

NCT06732232Relapsed, Refractory, Multiple Myeloma

Shanghai Cell Therapy Group Co.,Ltd

Early Phase 1

Shanghai

2024-12-12

Recruiting

A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of MK-6204 (SKB535) for Injection in Participants With Advanced Solid Tumors

NCT06726369Advanced Solid Tumors

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Phase 1

142

Xiamen, Wuhan, Beijing, Changsha, Chengdu, Chongqing, Fuzhou, Linyi

2024-12-12

Recruiting

A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)

NCT06716606Connective Tissue Diseases

DrugBelimumab

GlaxoSmithKline

Phase 3

514

Beijing, Chengdu, Hangzhou, Mianyang, Shanghai, Shenyang, Zhuzhou

2024-12-12

Recruiting

A Study on the Combined Use of Tocilizumab and Flupentixol-Melitracen in the Treatment of Thyroid-Associated Ophthalmopathy

NCT06927375Thyroid-Associated Ophthalmopathy

DrugTocilizumab

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Phase 4

Shanghai

2024-12-12

Recruiting

Surgical Competency for Robot-Assisted Thyroidectomy: Construction and Validation of a Robotic Thyroidectomy Assessment Score (RTAS)

NCT06730321Thyroid Cancer, Thyroid Nodule, Thyroid Diseases, Thyroid Cancer, Papillary

Shanghai 6th People's Hospital

Observational

200

Shanghai

2024-12-12

Recruiting

Dose-escalation Study of D-CMG Regimen for the Treatment of Elderly Newly Diagnosed AML Patients

NCT06651866Acute Myeloid Leukemia

The First Affiliated Hospital of Xiamen University

Phase 1

Xiamen

2024-12-12

Recruiting

Study of Fruquintinib Plus Sintilimab for Treatment of Advanced Endometrial Cancer

NCT06584032Advanced Endometrial Cancer

DrugsFruquintinib·Doxorubicin·Sintilimab·Paclitaxel

Hutchmed

Phase 3

412

Beijing, Chongqing, Fuzhou, Guangzhou, Nanning, Harbin, Zhengzhou, Changsha

2024-12-12

Recruiting

Safety and Efficacy of CAR-T Cell Therapy for Relapsed/refractory Neuroblastoma and Desmoplastic Small Round Cell Tumors: a Single-arm, Open-label Trial.

NCT06836505Neuroblastoma (NB), Desmoplastic Small Round Cell Tumor (DSRCT)

Sun Yat-Sen University Cancer Center

Phase 1/2

Guangzhou, Dongguan, Shanghai

2024-12-12

Recruiting

a Study of CT0596 in Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Plasma Cell Leukemia

NCT06718270Relapsed/Refractory Multiple Myeloma, Relapsed/Refractory Plasma Cell Leukemia

Shanghai Changzheng Hospital

Early Phase 1

Shanghai

2024-12-11

Recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

NCT05421858Candidemia, Candidiasis, Invasive

DrugsCaspofungin·Fosmanogepix·Fluconazole

Basilea Pharmaceutica

Phase 3

450

Beijing, Bengbu, Chengdu, Guangzhou, Hangzhou, Lishui, Liuzhou, Nanchang

2024-12-11

Active, closed

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

NCT06588855Moderately to Severely Active Ulcerative Colitis

DrugAfimkibart

Hoffmann-La Roche

Phase 3

350

Beijing, Kunming, Changsha, Chengdu, Guangzhou, Hangzhou, Huizhou, Nanning

2024-12-11

Recruiting

A Study for the Treatment of Metastatic Prostate Cancer With HRS-1167 Tablets Combined With Abiraterone Acetate Tablets and Prednisone

NCT06689163Prostate Cancer

DrugsAbiraterone Acetate （II）·HRS-1167·Prednisone Acetate

Jiangsu HengRui Medicine Co., Ltd.

Phase 1/2

Hefei, Changsha

2024-12-11

Active, closed

Optimal Combination of Adjuvant Radiotherapy and Immunotherapy for Breast Cancer

NCT07046195Hypofractionated Radiotherapy, Triple Negative Breast Cancer (TNBC), Immunotherapy

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Observational

250

Guangzhou

2024-12-11

Recruiting

The Safety and Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy for Peritoneal Metastatic Adenocarcinoma

NCT06743867Peritoneal Carcinoma Metastatic

Guangdong Provincial People's Hospital

Phase 1

Guangzhou

2024-12-11

Recruiting

Impact of Severe Obstructive Sleep Apnea-Hypopnea Syndrome on Auditory-Cognitive Processing

NCT07039500Obstructive Sleep Apnea, Auditory Processing Disorder

Peking University First Hospital

Observational

100

Beijing

2024-12-11

Not yet open

Evaluating an Insulin Pump for Time in Range (TIR) in Patients with Type 1 Diabetes

NCT06741943Type 1 Diabetes Mellitus, Insulin Pump, Time in Range

Tao Yuan，MD

Not applicable

Beijing

2024-12-11

Not yet open

Botulinum Toxin Injection Versus Prism Treatment in Small-angle Acute Acquired Concomitant Esotropia

NCT06714877Esotropia

Eye & ENT Hospital of Fudan University

Not applicable

100

Shanghai

2024-12-10

Not yet open

Orthopedic Intelligent Navigation System in the Treatment of Fresh Femoral Neck Fractures

NCT06713018Fracture of Neck of Femur

Chinese PLA General Hospital

Not applicable

300

Beijing

2024-12-10

Recruiting

Inaticabtagene Autoleucel (Inati-cel; CNCT19) Treatment for MRD-Positive B-ALL Patients in CR1

NCT06718244Acute Lymphoblastic Leukemia

DrugSingle of Inaticabtagene autoleucel

Ruijin Hospital

Phase 2

Shanghai

2024-12-10

Recruiting

Clinical Study of a Novel Sliding Compression Locking Plate in the Treatment of Fresh Femoral Neck Fractures

NCT06713291Fracture of Femoral Neck

Chinese PLA General Hospital

Not applicable

1,150

Beijing

2024-12-10

Recruiting

Establishment and Clinical Transformation of ADC Drug Efficacy Evaluation System for Breast Cancer Based on Molecular Imaging

NCT06715020Breast Cancer

DrugFluorodeoxyglucose

Peking University Cancer Hospital & Institute

Not applicable

Beijing

2024-12-10

By invitation

Intervention Effects of High-intensity Tai Chi in Mild or Moderate Asthma

NCT06728904Asthma

Yufen Wu, MD

Not applicable

Shanghai

2024-12-10

Not yet open

Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures

NCT06713031Fracture of Neck of Femur

Chinese PLA General Hospital

Not applicable

400

Beijing

2024-12-10

Recruiting

CR-CHOP+X in Previously Untreated DEL

NCT06701357DLBCL

DrugsCr-Chop·Decitabine·Orelabrutinib

Ruijin Hospital

Phase 2

Shanghai

2024-12-10

Recruiting

Efficacy of Different Durations of Dual and Quadruple Regimens for Helicobacter Pylori Eradication

NCT06723197HELICOBACTER PYLORI INFECTIONS

DrugsBismuth·Tetracycline·Vonoprazan·Amoxicillin

Shandong University

Phase 4

330

Jinan

2024-12-10

Recruiting

Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Centrally Located Early-stage Non-small Cell Lung Cancer

NCT06730295Lung Cancer (NSCLC)

Sun Yat-sen University

Phase 2

Guangzhou

2024-12-10

Recruiting

Integrated Radiotherapy-optimized ASCT Sequential CAR-T Therapy for Patients With Relapsed and Refractory B-NHL

NCT07059741Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-12-10

Recruiting

Ultrasound-guided Thermal Ablation for Papillary Thyroid Carcinoma

NCT06733740Papillary Thyroid Cancer

Chinese PLA General Hospital

Observational

3,000

Beijing

2024-12-10

By invitation

A Study to Evaluate the Efficacy and Safety of HSK31858 Tablets in Patients with Airway Mucus Hypersecretion

NCT06820749Asthma Bronchiale, Bronchiectasis, Chronic Obstructive Pulmonary Disease (COPD)

DrugHSK31858

Haisco Pharmaceutical Group Co., Ltd.

Phase 2

309

Beijing

2024-12-10

Recruiting

iGlarLixi CGM Study in Chinese T2D Individuals After OADs

NCT06671587Type 2 Diabetes (T2D)

DrugsIGlarLixi·Insulin glargine

Sanofi

Phase 4

678

Beijing

2024-12-10

Recruiting

A Multicenter Prospective Study Evaluating Concurrent Chemoradiotherapy Following Induction Immunochemotherapy for Esophageal Cancer Based on Dynamic ctDNA Monitoring

NCT06792786Esophageal Cancer, ctDNA

The Central Hospital of Lishui City

Not applicable

Jinhua, Lishui

2024-12-10

Recruiting

Study on the Safety and Efficacy of Intravenous Administration of IDOV-SAFETM in the Treatment of Advanced Solid Tumors

NCT06718946Advanced Malignant Solid Tumor

Fudan University

Early Phase 1

Shanghai

2024-12-10

Recruiting

68Ga-MY6349 PET/CT in Solid Tumors

NCT07046702Solid Tumor, Trop2, PET/CT

The First Affiliated Hospital of Xiamen University

Observational

300

Xiamen

2024-12-10

Recruiting

A Clinical Study of SHR-3276 for Injection in Patients With Advanced Malignant Tumors

NCT06643754Advanced Solid Tumors

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 1/2

115

Chongqing

2024-12-10

Recruiting

Efficacy and Safety of Triple-targeted Drug Therapy in Treatment-naive Patients With Non-low-risk PAH: A Real-world, Multicenter Study

NCT06753981Arterial Pulmonary Hypertension (PAH)

Qianfoshan Hospital

Observational

Jinan

2024-12-10

By invitation

The Effects of High-definition Transcranial Direct Current Stimulation on Balance Control in Older Adults With Chronic Low Back Pain

NCT06706479Chronic Low Back Pain

The Hong Kong Polytechnic University

Not applicable

Hong Kong

2024-12-10

Recruiting

A Multi-mode Thermophysical Immunotherapy Study for Breast Cancer Liver Metastases

NCT06567353Breast Neoplasms, Liver Neoplasms, Metastasis

Ruijin Hospital

Not applicable

Shanghai

2024-12-09

Recruiting

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

NCT06625593Advanced Solid Tumor

BeOne Medicines

Phase 1

168

Bengbu, Hefei, Beijing, Fuzhou, Xiamen, Nanning, Shijiazhuang, Harbin

2024-12-09

Active, closed

Application of Targeted Axillary Lymph Node Resection in Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: an Open-label, Multicenter Study

NCT07032220Breast Cancer Surgery, Neoadjuvant Therapy, Sentinel Lymph Node Biopsy (SLNB)

Fujian Medical University Union Hospital

Not applicable

175

Fuzhou

2024-12-09

Recruiting

Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules

NCT06733753Thyroid Nodule

Chinese PLA General Hospital

Observational

600

Beijing

2024-12-09

Recruiting

Clinical Trial of TQB3002 in Patients With Advanced Cancers

NCT06662760Advanced Cancer

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 1

150

Guangzhou, Shenzhen, Zhengzhou, Nanjing, Nanchang, Shanghai, Xi’an, Chengdu

2024-12-09

Recruiting

Long-term Follow-up Study of AL-001 Ophthalmic Injection in Subjects with WAMD

NCT06718816Wet Age-related Macular Degeneration (wAMD)

Beijing Anlong Biopharmaceutical Co., Ltd.

Observational

Beijing

2024-12-09

Recruiting

Adebrelimab Combined With Chemotherapy for the Esophageal Squamous Cell Carcinoma

NCT07430579Pathological Complete Remission, Objective Response Rate, Immune-related Adverse Events, Quality of Life

The Second Hospital of Shandong University

Not applicable

Jinan

2024-12-09

Active, closed

Application of 4DCT-Based Pulmonary Ventilation Imaging in Lung Cancer Radiotherapy

NCT07312682Lung Neoplasms, Radiation Pneumonitis

The Second Affiliated Hospital of Chongqing Medical University

Observational

202

Chongqing

2024-12-09

By invitation

Evaluating App-Based Vision Testing (WHOeyes) Combined With the Questionnaire as a Substitute for One-Week Postoperative In-Clinic Follow-Up in Age-Related Cataract Patients: A Multi-center Randomized Controlled Trial

NCT06429527Cataract Senile

Zhongshan Ophthalmic Center, Sun Yat-sen University

Not applicable

334

Guangzhou

2024-12-09

Recruiting

Predictive Value of Myelodysplastic Syndrome Stem Cells Determined by Multiparameter Flow Cytometry

NCT06569095Myelodysplastic Syndromes

Peking University People's Hospital

Observational

163

Beijing, Wuhan, Zhengzhou

2024-12-09

Recruiting

Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC

NCT06663306Lung Cancer (NSCLC), Leptomeningeal Metastasis

DrugsPemetrexed·Bevacizumab

Shanghai Chest Hospital

Phase 1

Shanghai

2024-12-09

Active, closed

A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis.

NCT06588686Idiopathic Pulmonary Fibrosis (IPF)

Vicore Pharma AB

Phase 2

378

2024-12-09

Recruiting

Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules

NCT06729762Thyroid Nodule (Benign)

Chinese PLA General Hospital

Observational

1,500

Beijing

2024-12-09

Recruiting

Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression

NCT06717048Myopia, Refractive Error - Myopia, Choroidal Thickness, Retina

Shanghai Eye Disease Prevention and Treatment Center

Not applicable

108

Shanghai

2024-12-09

Recruiting

Ultrasound-guided Thermal Ablation for Recurrent Thyroid Cancer

NCT06733766Recurrent Thyroid Cancer

Chinese PLA General Hospital

Observational

300

Beijing

2024-12-09

Recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

NCT06597019Familial Hypercholesterolemia - Heterozygous

DrugInclisiran

Novartis Pharmaceuticals

Phase 3

Beijing, Shanghai

2024-12-09

Recruiting

Long-term Follow-up Study of BRL-101 for TDT

NCT06298630Thalassemia, Beta

Bioray Laboratories

Observational

Guangzhou, Shenzhen, Nanning, Changsha, Tianjin, Guangxi

2024-12-08

Recruiting

Comparision of Endoscopic Discectomy and Microdiscectomy for the Treatment of Lumbar Spinal Stenosis

NCT06719037Lumbar Spinal Stenosis

Qilu Hospital of Shandong University

Not applicable

324

Jinan

2024-12-08

Recruiting

Blinatumomab in Refractory Active Childhood Systemic Lupus Erythematosus

NCT06789107Systemic Lupus Erythematosus (SLE), Children, Blinatumomab

DrugBlinatumomab

Mao Jianhua

Phase 1

Hangzhou

2024-12-08

Recruiting

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

NCT06679140COVID-19 SARS-CoV-2 Infection

DrugIbuzatrelvir

Pfizer

Phase 3

2,330

Chizhou, Beijing, Xiamen, Guangzhou, Nanning, Changsha, Nanchang, Changchun

2024-12-08

Recruiting

A Multicenter, Prospective, Cohort Study of Trop-2 ADC Combination Therapy for Advanced Triple-negative Breast Cancer

NCT06878625Evaluating the Efficacy of Trop-2 ADC Combination Therapy in Advanced Triple-Negative Breast Cancer

Tianjin Medical University Cancer Institute and Hospital

Phase 2

138

Tianjin

2024-12-06

Recruiting

Breathomics in the Diagnosis and Prediction of Radiotherapy-Induced Oropharyngeal Mucositis in Head and Neck Tumors

NCT06767488Head and Neck Tumors, Breathomics, Volatile Organic Compounds, Radiotherapy-induced Oral Mucositis

Nanfang Hospital, Southern Medical University

Observational

375

Guangzhou

2024-12-06

Active, closed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 in Participants With Dyslipidaemia

NCT06834932Dyslipidaemia

DrugsRosuvastatin 1·Rosuvastatin 2·AZD0780

AstraZeneca

Phase 2/3

432

Baotou, Beijing, Bengbu, Changchun, Changde, Changsha, Changzhou, Chengdu

2024-12-06

Recruiting

Study of SIM0508 Alone and in Combination in Patients With Advanced Solid Tumors

NCT06686745Advanced Solid Tumors

DrugOlaparib

Jiangsu Simcere Pharmaceutical Co., Ltd.

Phase 1

130

Shanghai, Chongqing

2024-12-06

Recruiting

A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients

NCT06497985Colorectal Cancer

DrugsTucidinostat·Fruquintinib·Chidamide·Sintilimab

Chipscreen Biosciences, Ltd.

Phase 3

430

Guangzhou

2024-12-06

Recruiting

A Study to Evaluate HB0034 in Healthy Chinese Adult Participants

NCT06716151Healthy

DrugHB0034

Shanghai Huaota Biopharmaceutical Co., Ltd.

Phase 1

Jinan

2024-12-06

Recruiting

The Efficacy and Safety of Precision REpetitive Transcranial Magnetic Stimulation in Alleviating Motor Symptom in Parkinson's Disease

NCT06383247Parkinson Disease, Transcranial Magenetic Stimualtion, Supplementary Motor Area

Anhui Medical University

Not applicable

290

Hefei

2024-12-06

Recruiting

Efficacy and Safety of Telitacicept in IgAN

NCT06654596IgA Nephropathy (IgAN), Kidney Diseases, Telitacicept, Glucocorticoid

DrugTelitacicept

Ruijin Hospital

Not applicable

118

Shanghai

2024-12-06

Recruiting

IB-T101 Injection for Treatment of Patients With Advanced Clear Cell Renal Cell Carcinoma

NCT06819293Advanced Clear Renal Cell Carcinoma, Adult

Grit Biotechnology

Phase 1

Wuhan

2024-12-06

Recruiting

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

NCT06667908Carcinoma, Non-Small-Cell Lung

DrugsJNJ-90301900·Durvalumab

Johnson & Johnson Enterprise Innovation Inc.

Phase 2

130

Dongguan, Guangzhou, Jinan

2024-12-06

Recruiting

The Association Between Age-related Peripheral Blood Components and Treatment Efficacy in Breast Cancer

NCT06718010Breast Cancer, Age

Fudan University

Observational

120

Shanghai

2024-12-05

Recruiting

Study of SC-102 in Patients With Advanced Solid Tumors

NCT06710158Advanced Solid Cancers

Tianjin ConjuStar Biologics Co., Ltd.

Phase 1

120

Shanghai

2024-12-05

Recruiting

A Phase III Clinical Trial for Efficacy and Safety Evaluation of JP-1366 Tablets on Reflux Esophagitis

NCT06850480Reflux Esophagitis (RE)

Livzon Pharmaceutical Group Inc.

Phase 3

356

Beijing

2024-12-05

Active, closed

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With AIHA Who Have Failed ≥3 Lines of Therapy.

NCT06733610Autoimmune Hemolytic Anemia, CD19/BCMA CAR T-cells, Universal Allogeneic CAR T-cells

Institute of Hematology & Blood Diseases Hospital, China

Phase 1

Tianjin

2024-12-05

Recruiting

nVNS for the Prevention and Treatment of Primary Headache

NCT06277063Primary Headache, Migraine in Adolescence, Migraine in Children, Cluster Headache

Nanfang Hospital, Southern Medical University

Not applicable

Guangzhou

2024-12-05

Active, closed

Effects of DL-endopeptidase Producing Probiotics on Human Intestinal NOD2 Ligands and Related Functions

NCT06716047Microecological Therapy, Probiotic Intervention

Zhujiang Hospital

Early Phase 1

Guangzhou

2024-12-05

Recruiting

Anlotinib-based Combination Therapy in Patients with Hormone Receptor-positive（HR+） Metastatic Breast Cancer(MBC) .

NCT06734533HR+ Breast Cancer

Hunan Cancer Hospital

Observational

Changsha

2024-12-05

Recruiting

Pleural Strain by Speckle-Tracking Ultrasound: Feasibility and Driving Pressure Associations

NCT06911450Ventilation, Mechanical, ARDS (Acute Respiratory Distress Syndrome)

First Affiliated Hospital of Wannan Medical College

Observational

Wuhu

2024-12-05

Recruiting

Target-specific immunoPET Imaging of Digestive System Carcinoma

NCT06715839Malignancy, Digestive Cancer, Digestive System Neoplasm, Digestive System Carcinoma

Drugs[18F]F-RESCA-RB14·[18F]F-RESCA-T4·[68Ga]Ga-NOTA-T4

RenJi Hospital

Not applicable

400

Shanghai

2024-12-04

Active, closed

Nipocalimab in Moderate to Severe Sjogren's Disease

NCT06741969Sjogrens Syndrome

DrugNipocalimab

Janssen Research & Development, LLC

Phase 3

655

Beijing, Changsha, Changzhou, Chengdu, Dazhou, Ganzhou, Guangzhou, Guiyang

2024-12-04

Recruiting

Study on Human Bioequivalence of Triprerelin Acetate for Injection

NCT06683066Prostate Cancer (CRPC)

DrugDiphereline

The Affiliated Hospital of Qingdao University

Phase 1

120

Qingdao

2024-12-04

Active, closed

Evaluate TQ-A3334 Combined Nucleoside (Acid) Analogs in the First Treatment/Treatment of Chronic HBV Infection

NCT06706310Chronic Hepatitis B

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 2

116

Chongqing, Guangzhou, Shenzhen, Liuzhou, Wuhan, Changsha, Wuxi, Changchun

2024-12-04

Recruiting

Application of a New Surgical Technique in Proximal Gastrectomy: a Prospective, Multicenter Randomized Controlled Study

NCT06679244Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy

Huashan Hospital

Not applicable

Shanghai

2024-12-04

By invitation

Comparison of the Effects of Hydromorphone and Nalbuphine Patient Controlled Analgesia in Postoperative Pain After Cesarean Section

NCT06716359Postoperative Pain, Patiet Controlled Analgesia

Huazhong University of Science and Technology

Observational

240

Wuhan

2024-12-04

Recruiting

Hydrocortisone in Hormone Replacement Therapy for Large Pituitary Neuroendocrine Tumors

NCT06679816Pituitary Adenoma, Pituitary Neuroendocrine Tumor

Beijing Tiantan Hospital

Phase 4

882

Beijing

2024-12-04

Recruiting

Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)

NCT06565910Femoral Neck Fractures, Femur Head Necrosis, Hip Fractures

DrugsLiposomal bupivacaine·Ropivacaine·Bupivacaine

Huazhong University of Science and Technology

Phase 4

Wuhan

2024-12-04

Recruiting

Efficacy of Upadacitinib After NECS in Vitiligo

NCT06454461Vitiligo

DrugUpadacitinib

Jilin University

Not applicable

Changchun

2024-12-04

Recruiting

NabPE With or Without Serplulimab for Early-stage HR+/HER2- Breast Cancer.

NCT06781281Breast Cancer Invasive

DrugsNabPE·Serplulimab

Henan Cancer Hospital

Observational

709

Zhengzhou

2024-12-04

Recruiting

A Study of AK112, a PD-1/ VEGF Bispecific Antibody, for Resectable Hepatocellular Carcinoma With High Recurrence Risk

NCT06930573HCC

DrugIvonescimab

The First Affiliated Hospital of Zhengzhou University

Phase 4

Zhengzhou

2024-12-04

Recruiting

Trop2-targeting NIR-II Molecular Probe for Precision Diagnosis of Oral Cancer

NCT07794813Oral Squamous Cell Carcinoma (OSCC), Diagnosis

Yunnan Cancer Hospital

Observational

Kunming

2024-12-03

Recruiting

HRS-4642 in Combination With AG for Neoadjuvant and Adjuvant Treatment of Pancreatic Cancer

NCT06587061Pancreatic Cancer

DrugHRS-4642

Ruijin Hospital

Phase 2

Shanghai

2024-12-03

Recruiting

The Value of 68Ga-FAPI PET/CT in the Efficacy Evaluation of Advanced Unresectable Hepatocellular Carcinoma Patients Undergoing Systemic Antitumor Therapy

NCT06746194Hepatocellular Carcinoma (HCC)

Ruijin Hospital

Observational

Shanghai

2024-12-03

Recruiting

Neoadjuvant Chemotherapy Plus Pyrotinib and Trastuzumab for HER2-positive Breast Cancer (NEOTORCH-BREAST05)

NCT06832904HER2-positive Breast Cancer, Neoadjuvant Therapy, Pyrotinib

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-12-03

Recruiting

Fecal Microbiota Transplantation in Patients With Multiple Drug Resistant Klebsiella Pneumoniae Pneumonia

NCT06641778Klebsiella Pneumoniae Pneumonia

luxia Kong

Not applicable

100

Wuhan

2024-12-03

Not yet open

Neoadjuvant Therapy of Targeted Immunotherapy Combined With Chemotherapy for Locally Advanced HNSCC

NCT06699498Head and Neck Squamous Cell Carcinoma, Neoadjuvant Therapy, PD-L1, Anlotinib

DrugsPaclitaxel （Albumin Bound）·Benmelstobart·Anlotinib·Cisplatin

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2024-12-03

Recruiting

Oxycodone Versus Sufentanil in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy

NCT06690307Laparoscopic Hysterectomy

Affiliated Hospital of Nantong University

Phase 4

Nantong

2024-12-03

Recruiting

Efficacy and Safety of Vonorasan Versus Esomeprazole in the Treatment of Ulcers After Endoscopic Submucosal Dissection

NCT06526455Ulcers, Gastric

DrugsVonoprazan·Esomeprazole

Shicai Ye

Phase 4

196

Guangzhou, Maoming, Zhanjiang, Sanmenxia

2024-12-02

Recruiting

Exploration of the Dynamic Changes and Mechanisms of the Immune Microenvironment in Advanced Colorectal Cancer Treated With IBI363 Combination Therapy

NCT06946745Immunotherapy

jianming xu

Observational

Beijing

2024-12-02

Active, closed

Sintilimab in Combination with Chemotherapy ± Local Treatment for Om-G/GEJ

NCT06739161Gastroesophageal Junction Adenocarcinoma

Jiangsu Cancer Institute & Hospital

Phase 2

120

Nanjing

2024-12-02

Recruiting

The Influence of Systematic Psychological Intervention on Patients About VSD Drainage Surgery

NCT06424561Chronic Wounds

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Not applicable

Yiwu

2024-12-02

Recruiting

Clinical Study of Cord Blood-derived IL-10/IL-15 CD19-CAR NK in the Treatment of Refractory/Relapsed B-cell NHL

NCT06707259B-cell Non Hodgkin Lymphoma

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 1

Hangzhou

2024-12-01

Active, closed

Using ctDNA to Guide Treatment Decisions for Stage III Gastric Cancer

NCT06939439Gastric Cancer Stage III

DrugTislelizumab

The First Affiliated Hospital with Nanjing Medical University

Phase 3

416

Nanjing

2024-12-01

Active, closed

Microplastics in Paraneoplastic and Intratumoral for Colorectal Cancer

NCT07063550Colorectal Cancer (MSI-H), Microplastic Exposure

Dong Peng

Observational

100

Chongqing

2024-12-01

Not yet open

Tofacitinib in Patients With Amyotrophic Lateral Sclerosis

NCT06689982Amyotrophic Lateral Sclerosis

DrugTofacitinib

Beijing Tiantan Hospital

Early Phase 1

Beijing

2024-12-01

Recruiting

The Addictive Diagnostic Value of Apparent Diffusion Coefficients to bpMRI in the Diagnosis of Prostate Cancer

NCT06737588Prostate Cancer

Anhui Provincial Hospital

Observational

600

Hefei, Wuhu

2024-12-01

Recruiting

Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeutic Management of Non-Small Cell Lung Cancer

NCT06926179Lung Cancer (NSCLC), Neoadjuvant Immunotherapy, Radiotherapy, Lung Surgery

Peking University Cancer Hospital & Institute

Observational

500

Beijing, Hohhot, Kunming

2024-12-01

Not yet open

Research on the Application of Patient Navigation-based Management Model of Patients After LEEP

NCT06695871Cervical Intraepithelial Neoplasias

Peking University People's Hospital

Not applicable

128

Beijing

2024-12-01

Active, closed

Postural Decoding for Post-Stroke Shoulder Pain: A RCT.

NCT06763796Stroke; Sequelae

Shenzhen Baoan District Fuyong People's Hospital

Not applicable

Shenzhen

2024-12-01

Not yet open

Prognostic Study of Via Dynamic Change of dT-DNA in Drainage Fluid After Radical Prostatectomy

NCT06707974Prostatic Neoplasms, ctDNA

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Observational

100

Shanghai

2024-12-01

Not yet open

BuCy Vs. TBICy for Allo-HSCT in T-ALL Patients

NCT06673459T-Cell Lymphocytic Leukemia, ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Total Body Irradiation, Chemotherapy

The First Affiliated Hospital of Soochow University

Phase 3

430

Suzhou

2024-12-01

Not yet open

CAR-T Technology for Recurrent/Refractory Malignant Hematological and Lymphatic Tumors

NCT06647329CAR-T Cell Therapy, Lymphomas

Mingzhi Zhang

Phase 1

Zhengzhou

2024-12-01

Not yet open

Exploration of the Efficacy and Mechanisms of Lymphaticovenous Anastomosis in the Treatment of Alzheimer's Disease

NCT06706947Alzheimer&#39;s Disease (AD)

Luo Xinxin

Not applicable

Shenzhen

2024-12-01

Recruiting

ALI & Pulmonary HA Deposition After SAH

NCT06628531Subarachnoid Haemorrhage (SAH)

Tianjin Medical University

Observational

Tianjin

2024-12-01

By invitation

Correlation Analysis of Xpert Carba-R Detection of Non-colonized CRE in BALF and Rectal Swabs From Patients With LRTI

NCT06636890Carbapenem-Resistant Enterobacteriaceae, Lower Respiratory Tract Infections

The First Affiliated Hospital with Nanjing Medical University

Observational

200

Nanjing

2024-12-01

Not yet open

A Randomized Controlled, Open, Single-center Clinical Study Evaluating the Efficacy and Safety of Umbilical Cord Blood Mononuclear Cells in Patients with Refractory Immune Effector Cell-related Hemocytopenia

NCT06729320Refractory Immune Effector Cell-related Hemocytopenia

Beijing GoBroad Hospital

Not applicable

Beijing

2024-12-01

Recruiting

Impact of Recombinant Humanized Type III Collagen on the Immediate and Long-term Effects of Breast Tumor Surgery

NCT06725082Breast Cancer, Collagen Protein

Peking University People's Hospital

Phase 1

Beijing

2024-12-01

Recruiting

tSCS Combined With Rehabilitation Training in Treating Paraplegic Patients After SCI

NCT07907952Spinal Cord Injury, Paraplegia, Spinal

Beijing Tsinghua Chang Gung Hospital

Not applicable

Beijing

2024-12-01

Recruiting

Pre-Anesthesia Visit: Analysis of Coverage Rate of Visit Content and Surgical Patients' Understanding of Information

NCT06735183To Assess the Coverage of Anesthesiology Residents' Explanations of the Content of the Visit, Patients' Understanding of the Content of the Anesthesia Approach Through the Physician's Explanations

Anshi Wu

Observational

110

Beijing

2024-12-01

Recruiting

Orelabrutinib Combined With Rituximab Versus R-CVP in the Untreated MZL： A Randomized, Open Phase II Trial

NCT06700798Marginal Zone Lymphoma(MZL)

DrugsOrelabrutinib·Vincristine·Prednisone·Rituximab

Fei Li

Phase 2

Nanchang

2024-12-01

By invitation

Efficacy and Safety of Cadonilimab and Chemoradiotherapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

NCT06715501Locally Advanced Esophageal Squamous Cell Carcinoma, II-IIIB Stages

DrugsCarboplatin/Paclitaxel·Cadonilimab

First Affiliated Hospital of Ningbo University

Not applicable

Ningbo

2024-12-01

Recruiting

Evaluation of Targeted Biopsy Plus Sextant Biopsy in Diagnosis of Prostate Cancer

NCT06684652Prostate Cancer

Peking University First Hospital

Not applicable

300

Beijing

2024-12-01

Recruiting

Artificial Intelligence-based Model for the Prediction of Occult Lymph Node Metastasis and Improvement of Clinical Decision-making in Non-small Cell Lung Cancer

NCT06684418NSCLC (Non-small Cell Lung Cancer), Artificial Intelligence (AI), Lymphnode Metastasis

Fudan University

Observational

6,000

Shanghai

2024-12-01

Active, closed

Identification of Microplastics in Liver, Stomach, Blood, and Feces of Obese Patients and Their Association Analysis with Macrogenomics and Metabolomics.

NCT06826586Obesity and Overweight

First Affiliated Hospital of Chongqing Medical University

Observational

Chongqing

2024-12-01

Recruiting

The Use of Propranolol in the Perioperative Period of Resectable Gastrointestinal Tumors

NCT06775080Gastrointestinal Tumors

DrugPropranolol

Huashan Hospital

Phase 2

Shanghai

2024-12-01

By invitation

Feasibility Study on the Application of Bionic Healing Abutments in Implant Impressions

NCT07514585Dentition Defect, Healing Abutment

Fujian Medical University

Observational

Fuzhou

2024-12-01

Not yet open

Artificial Intelligence Models for Precision Prediction and Treatment of Prostate Cancer

NCT06662708Prostate Cancer, Prostate Intraductal Carcinoma, Prostate Cancer Aggressiveness, Prostate Cancer Stage

Shao Pengfei

Not applicable

200

Nanjing

2024-12-01

Not yet open

Zanubrutinib, Obinutuzumab and Lenalidomide (ZGR) in High-risk Treatment-naive Patients with Follicular Lymphoma (FL)

NCT06549335Follicular Lymphoma

Ruijin Hospital

Phase 2

Shanghai

2024-12-01

Recruiting

Adaptive Radiotherapy for Genitourinary Cancers

NCT07324798Prostate Cancer (Post Prostatectomy), Bladder Cancer

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Not applicable

Beijing

2024-12-01

Recruiting

Minimal Vitrectomy Surgery for Epiretinal Membrane

NCT07019896Epiretinal Membrane, Macular Edema (ME), Nuclear Cataract

Peking Union Medical College Hospital

Not applicable

140

Beijing

2024-12-01

Not yet open

A Novel Classification of Sagittal Spinal Alignment to Aid Surgical Planning for Adult Spinal Deformity

NCT06470152Adult Spinal Deformity, Sagittal Deformity, Sagittal Alignment, Sagittal Imbalance

Xuanwu Hospital, Beijing

Not applicable

200

Beijing

2024-12-01

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of r/r B-NHL Clinical Research

NCT06716164Non-hodgkin Lymphoma,B Cell

Zhejiang University

Early Phase 1

Hangzhou

2024-12-01

Not yet open

Observational Study of Sputum Inflammation Phenotypes and Clinical Outcomes in Non-Cystic Fibrosis Bronchiectasis

NCT06715956Non-cystic Fibrosis Bronchiectasis (NCFBE)

Guangzhou Institute of Respiratory Disease

Observational

400

Guangzhou

2024-12-01

Recruiting

Ophthalmic AI-Assisted Medical Decision-Making

NCT06755060Ocular Diseases

The Eye Hospital of Wenzhou Medical University

Not applicable

100,000

Zhuhai, Wenzhou

2024-12-01

Recruiting

A Single-arm, Prospective Study of TBI + BUMEL As a Conditioning Regimen for Salvage HSCT in Patients with R/R AML

NCT06879847Relapsed or Refractory Acute Myeloid Leukemia

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-12-01

Not yet open

Effects of Monitoring Blood Pressure During Pregnancy

NCT06217913Birth Weight, Weight Gain Trajectory

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Not applicable

400

Shanghai

2024-12-01

Not yet open

First-line Treatment of Advanced/unresectable DDLPS

NCT06694324Dedifferentiated Liposarcoma, Soft Tissue Sarcoma (STS)

DrugsLiposomal doxorubicin·Apatinib·Camrelizumab

Fudan University

Phase 2

Shanghai

2024-12-01

Recruiting

Observation of Pain During the Treatment of Great Saphenous Vein Using Microwave Ablation， and Analysis of Related Factors

NCT06693245Vascular Disease，Peripheral, Venous Insufficiency of Leg, Varicose Veins of Lower Limb

Chengdu University of Traditional Chinese Medicine

Observational

155

Chengdu

2024-12-01

Recruiting

COLORECTUM+ Digital System for Postoperative Quality Improvement in Colorectal Cancer

NCT06685497Colorectal Carcinoma

RenJi Hospital

Not applicable

236

Shanghai

2024-12-01

Active, closed

A Study on the Assessment of Difficult Weaning in Patients With Acute Respiratory Failure Undergoing Mechanical Ventilation Based on Machine Learning EIT-pendelluft: A Multicenter Retrospective Study.

NCT06756204Acute Respiratory Failure Requiring Intubation

Ruijin Hospital

Observational

216

Shanghai

2024-12-01

Recruiting

Effects of Sleep Restriction and Stimulus Control in Chronic Insomnia Patients

NCT06658184Chronic Insomnia

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-12-01

Recruiting

ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC

NCT06426511Lung Cancer, Nonsmall Cell

DrugToripalimab

Sun Yat-sen University

Phase 2

Guangzhou

2024-12-01

Active, closed

Real-world Study on Fenestrated Stent for Thoracic Aortic Dissection

NCT07268755Thoracic Aortic Dissection, Thoracic Aortic Disease

Qingyou Meng

Observational

320

Shanghai

2024-12-01

Recruiting

Angioplasty With Shockwave IVL Catheter System in Femoropopliteal Lesions

NCT06713850Peripheral Artery Disease (PAD), Chronic Limb Threatening Ischemia

Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology

Observational

130

Wuhan

2024-12-01

Recruiting

A Bladder-Sparing Treatment Strategies of Large-Volume Non-Muscle-Invasive Bladder Cancer

NCT06735287Bladder Cancer, NMIBC

The First Affiliated Hospital with Nanjing Medical University

Not applicable

Nanjing

2024-12-01

Recruiting

21-gene in Elder Breast Cancer Patients With Lymph Node Metastasis

NCT06891651Breast Cancer Metastatic, Breast Cancer Survival

Qilu Hospital of Shandong University

Observational

Jinan

2024-12-01

Not yet open

A Prospective, Non-interventional Cohort Study of Subsolid Pulmonary Nodules

NCT06458673Solitary Lung Nodule, Multiple Pulmonary Nodules

Guangdong Provincial People's Hospital

Observational

1,184

Guangzhou

2024-12-01

Recruiting

The Impact of Anxiety/Depression on the Efficacy of Asthma Control Drugs and the Construction of a Predictive Model for the Risk of Acute Asthma Attacks

NCT07679321Anxiety/Depression and Asthma

Xiangya Hospital of Central South University

Observational

256

Changsha

2024-12-01

Recruiting

Shanghai Prospective Registry Study of Ischemic Stroke

NCT07171242Ischemic Stroke

Qiang Dong

Observational

15,000

Shanghai

2024-12-01

Not yet open

Prognostic Study of Prostate Cancer Via Dynamic Change of PSA in Peritoneal Drainage Fluid After Radical Prostatectomy

NCT06608225Prostatic Neoplasms, Prostate-Specific Antigen

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Observational

100

Shanghai

2024-12-01

Recruiting

Clinical Research on 68Ga-FAPI PET/CMR in Cardiovascular Diseases

NCT07063043Cardiovascular Diseases (CVD)

Shanghai East Hospital

Observational

Shanghai

2024-12-01

Not yet open

Protective Effect of RIPC Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery (Panda VII)

NCT06707350Cardiopulmonary Bypass, Cardiovascular Diseases, Inflammatory Response During Cardiac Surgery

Nanjing Medical University

Not applicable

500

Nanjing

2024-12-01

Recruiting

Allogeneic CD19-targeted CAR-γδT Cell Infusion Therapy in Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia

NCT06696833B-Cell Acute Lymphoblastic Leukemia, Adult

DrugsFludarabine·Cyclophosphamide

The First Affiliated Hospital of Soochow University

Early Phase 1

Suzhou

2024-12-01

Recruiting

Blinatumomab Combined With Low-dose DLI as Maintenance Therapy After Transplantation for B-ALL

NCT07677878ALL (Acute B-Lymphoblastic Leukemia)

DrugBlinatumomab

Liping Dou

Phase 1

Beijing

2024-12-01

Recruiting

SCS Therapy for Patients With Bladder and Bowel Dysfunction After SCI

NCT07511244Bladder and Bowel Dysfunction, SCI - Spinal Cord Injury

Beijing Tsinghua Chang Gung Hospital

Not applicable

Beijing

2024-12-01

Active, closed

Cognitive Function and EEG Brain Network Remodeling Among Users of Hearing Aids With ARHL

NCT06893432Age-related Hearing Loss, Age-related Cognitive Decline, Depression, Sleep Disturbance

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Observational

Guangzhou

2024-12-01

Recruiting

Comparing the Incidence of Parastomal Hernia After Mesenteric Molding Suturing and Non-molding Suturing in Colostomy Surgery

NCT06674187Parastomal Hernia

The First Affiliated Hospital with Nanjing Medical University

Not applicable

234

Nanjing

2024-12-01

Not yet open

MCE Identifying Bleeding Lesions in Patients with Antiplatelet Drugs-Related Acute Non-Hematochezia Gastrointestinal Bleeding

NCT06698874Gastrointestinal Bleeding, Antiplatelet Therapy

Changhai Hospital

Not applicable

204

Qinghai, Shanghai, Xi'an

2024-12-01

Recruiting

The Role of AAT After Abdominal Surgery Based on RWS

NCT06580197Acupuncture, Ear, Gastroparesis

Peking Union Medical College Hospital

Observational

159

Beijing

2024-12-01

Recruiting

Diagnosis, Prognosis, and Mechanisms in Panvascular Disease

NCT07151183Panvascular Diseases, Cardiovascular Diseases

Jinwei Tian

Observational

1,000

Harbin

2024-12-01

Recruiting

A Clinical Observation Study of a Chinese Patent Medicine Combined With Tamsulosin in Improving Sleep and Nocturia Symptoms After Enucleation of the Prostate

NCT07357324Benign Prostatic Hyperplasia, Nocturia Associated With Nocturnal Polyuria

DrugsTamsulosin Hydrochloride·Tamsulosin

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Phase 4

136

Yiwu

2024-12-01

Recruiting

Efficacy and Safety of Taitacept in Treatment of Refractory or Recurrent Anti-NMDAR/anti-LGI1 Encephalitis

NCT06510283Anti-N-Methyl-D-Aspartate Receptor Encephalitis

Beijing Tongren Hospital

Phase 2

Beijing

2024-12-01

Recruiting

Intra-arterial Chemotherapy Combined with Radiotherapy and Immunotherapy for HNSCC

NCT06725498Head and Neck Squamous Cell Carcinoma

DrugsAlbumin-Bound Paclitaxel·Cisplatin

Beijing Tongren Hospital

Phase 2

Beijing

2024-12-01

Recruiting

Efficacy and Safety of Vorolanib Monotherapy As Third-line or Later Treatment for Advanced Non-small Cell Lung Cancer Patients: a Single-arm, Prospective, Open-label Phase II Clinical Study

NCT06728852Advanced Non-small Cell Lung Cancer (NSCLC), Recurrent or Metastatic Lung Cancer, Third-line and Beyond Therapy, Angiogenesis Inhibition in Oncology

Li-kun Chen

Phase 2

Guangzhou

2024-12-01

Recruiting

Romiplostim N01 for Platelet Recovery in Adult Hematologic Malignancies Patients Undergoing UCBT

NCT06693791Platelet Recovery After Umbilical Cord Blood Transplantation

DrugIpilimumab

Anhui Provincial Hospital

Phase 2

Hefei

2024-12-01

Not yet open

Study of EPI-003 in Select Nucleos(t)Ide Analogue-Treated, Chronic Hepatitis B Patients

NCT06661148Chronic Hepatitis B, HBV (Hepatitis B Virus)

DrugEPI-003

Epigenic Therapeutics, Inc

Phase 1

Hong Kong

2024-12-01

Active, closed

The Association Between Microplastics and Macrogenomics and Metabolomics in Gastric Cancer

NCT06856382Gastric Cancers

Dong Peng

Observational

Chongqing

2024-12-01

Active, closed

The Impact of Targeted Temperature Management Duration on Thrombin Function in Cardiac Arrest Patients

NCT06543849Targeted Temperature Management, Cardiac Arrest, Thrombin Function, Treatment Duration

Tang Ziren

Not applicable

Beijing

2024-12-01

Not yet open

Clinical Observation on the Safety and Efficacy of Cardonilmab in the Treatment of Second-line and Above Advanced Melanoma and Advanced Renal Cancer

NCT06670300Participants Who Had Received Second-line or Higher Advanced Melanoma and Advanced Renal Cancer

YongZhang

Phase 2

Zhengzhou

2024-12-01

Recruiting

Comparative Analysis of Radiofrequency Ablation and Microwave Ablation Procedures for the Treatment of Small Saphenous Varicose Veins

NCT06711120Varicose Veins of Lower Limb, Venous Insufficiency of Leg, Vascular Disease，Peripheral

Chengdu University of Traditional Chinese Medicine

Not applicable

150

Chengdu

2024-12-01

Active, closed

Evaluating the Efficacy of Structured Exercise Interventions in Alleviating Aromatase Inhibitor-Induced Arthralgia in Breast Cancer Survivors: a Pilot Study Protocol

NCT06754293Musculoskeletal Symptoms, Breast Cancer, Endocrine Therapy, Aromatase Inhibitors

Fudan University

Not applicable

Shanghai

2024-12-01

Recruiting

The Clinical Application of Ultramicro-flow Technique in the Treatment of Benign Uterine Tumors With High-intensity Focused Ultrasound

NCT06435663Patients With Uterine Fibroids Receiving HIFUA Treatment ,and Can Undergo Regular Follow-up

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Not applicable

Yiwu

2024-12-01

Recruiting

Risk Stratification and MRD-driven Maintenance for MM After ASCT

NCT06697483Multiple Myeloma

DrugsDaratumumab·Lenalidomide

Peking University People's Hospital

Not applicable

100

Beijing, Harbin

2024-12-01

Recruiting

Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery

NCT07601282Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Observational

382

Shanghai

2024-12-01

Recruiting

Effects of Cognitive Correction and Stimulus Control in Chronic Insomnia Patients

NCT06658158Chronic Insomnia

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-12-01

Recruiting

Environmental and Behavioral Factors in Infertility and ART Outcomes

NCT07384676Environmental Exposure, Assisted Reproductive Technology, Prospective Study

The Third Xiangya Hospital of Central South University

Observational

5,000

Changsha

2024-12-01

Recruiting

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

NCT06497530Extensive-Stage Small Cell Lung Cancer

DrugsLurbinectedin·Serplulimab·Etoposide·Carboplatin

Guangzhou Institute of Respiratory Disease

Phase 2

Guangzhou

2024-12-01

Recruiting

Repeated Transcranial Magnetic Stimulation for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized Clinical Trial

NCT07581756Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D), Repetitive Transcranial Magnetic Stimulation (rTMS), Chronic Diarrhea

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-12-01

Recruiting

Laser Acupuncture for Idiopathic Bell's Palsy

NCT06732622Bell Palsy

Beijing Tongren Hospital

Not applicable

360

Beijing

2024-12-01

Recruiting

Real-World Study of Niraparib in First-Line Maintenance Therapy for Advanced Epithelial Ovarian Cancer

NCT07783022Ovarian Cancer

DrugNiraparib

Fudan University

Observational

1,920

Shanghai

2024-12-01

By invitation

Risk Model for Metastasis Detection of Neuroblastoma

NCT06703944Neuroblastoma (NB), Prognosis, Bone Marrow Metastasis, Bone Metastases

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Observational

500

Shanghai, Hangzhou, Shenzhen

2024-12-01

Active, closed

Treatment Duration of IPA

NCT06583512Invasive Aspergillosis, Antifungal Therapy

Peking University People's Hospital

Observational

Beijing

2024-12-01

Recruiting

The Application of Eye-Tracking Technology in Perioperative Management and Education

NCT06766539Eye-tracking Technology, Medical Education, Perioperative Management, Attention Distribution

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

300

Hangzhou

2024-12-01

Active, closed

Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery

NCT06751342Cataract

Wenzhou Medical University

Observational

Wenzhou

2024-12-01

Not yet open

Efficacy of Organoid-Based Chemotherapy Drug Precision Screening to Guide Treatment for Thyroid Cancer

NCT06713057Locally Advanced Thyroid Gland Carcinoma, Thyroid Cancer

DrugsGemcitabine alone·Vindesine·Doxorubicin·Adrucil

West China Hospital

Phase 2

Chengdu

2024-12-01

Recruiting

Cohort Study on the Prognosis and Influencing Factors in Elderly Patients With Hip Fractures in Multicenter of China

NCT07847164Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)

Beijing Hospital

Observational

10,000

Beijing

2024-12-01

Recruiting

Y-90 SIRT for Unresectable HCC Larger Than 7cm

NCT06707233Hepatocellular Carcinoma Non-Resectable

Second Affiliated Hospital of Guangzhou Medical University

Phase 2

Guangzhou

2024-12-01

Recruiting

A Prospective Cohort Study on the Treatment of Locally Advanced Gastric Cancer

NCT06760858Gastric Cancer, Gastroesophageal Junction Cancer

DrugTislelizumab

Southwest Hospital, China

Observational

122

Chongqing

2024-12-01

Recruiting

Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial)

NCT03547232Acute Pancreatitis, Complication, Mortality Rate, Organ Failure, Multiple

DrugIndomethacin

Peking Union Medical College Hospital

Phase 4

1,504

Beijing, Guiyang, Baoding, Harbin, Dengzhou, Nanyang, Huaian, Nantong

2024-12-01

Recruiting

Effect of Premedication With Pronase on Mucosal Cleanliness During EGD

NCT06713421Esophageal Cancer, Gastric Cancer

DrugsDimethicone·Pronase

Changhai Hospital

Not applicable

3,000

Shanghai

2024-12-01

Active, closed

Efficacy of Liposomal Bupivacaine Scalp Nerve Block for Postoperative Pain Management After Supratentorial Craniotomy

NCT07344181Postoperative Care

Beijing Tiantan Hospital

Not applicable

118

Beijing

2024-12-01

Not yet open

ARTA-based Chemo-free Bridging/Maintenance Therapy in CAR-T Treatment for High-Risk R/R B-NHL Ineligible for HDCT and ASCT

NCT06646666B-cell Non Hodgkin Lymphoma

DrugsAll-trans retinoic acid·Car-T·Zanubrutinib

Ruijin Hospital

Phase 2

Shanghai

2024-12-01

Recruiting

Study to Assess the Efficacy and Safety of GP681 Versus Placebo for Postexposure Prophylaxis Against Influenza

NCT06574503Influenza

DrugsGP681·GP681 Simulant

Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Phase 3

748

Hanzhou

2024-12-01

Recruiting

Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)

NCT06960369Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D), Repetitive Transcranial Magnetic Stimulation (rTMS), Probiotic

The First Affiliated Hospital of Soochow University

Phase 1

400

Suzhou

2024-12-01

Not yet open

Foldable Capsular Scleral Buckling Versus Vitrectomy in Medium-complex Rhegmatogenous Retinal Detachment Treatment

NCT06610786Rhegmatogenous Retinal Detachment

Eye & ENT Hospital of Fudan University

Not applicable

100

Shanghai

2024-12-01

Recruiting

Induction Immunotherapy Combined With Chemotherapy Followed by Concurrent Chemoradiotherap and Immunotherapy for Cervical Cancer

NCT07092696Cervical Cancer

DrugToripalimab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-12-01

Active, closed

Balloon-Assisted Enteroscopic Treatment for Phytobezoar

NCT06877559Phytobezoar; Intestine

Shandong University

Observational

Jinan

2024-12-01

Recruiting

Clinical Study on the Safety, Efficacy and Pharmacokinetics of Telpegfilgrastim in Pediatric Cancer Patients with Chemotherapy

NCT06857292Chemotherapy-Induced Neutropenia

DrugTelpegfilgrastim

Sun Yat-sen University

Phase 2

Guangzhou

2024-12-01

Recruiting

Combined Recanalization Therapy for Acute Large Vessel Occlusion Stroke

NCT07115511Stroke

Tianjin Huanhu Hospital

Not applicable

Tianjin

2024-12-01

Active, closed

Growth Evaluation, Health Promotion, and Clinical Management in Children and Adolescents With Thalassemia

NCT06931912Thalassemia Intermedia, Thalassemia Major, Growth Delay, Puberty, Delayed

Institute of Hematology & Blood Diseases Hospital, China

Not applicable

385

Tianjin

2024-12-01

Recruiting

CD70-CAR-NK Cell Therapy for T Cell Lymphoma and Acute Myeloid Leukemia

NCT06696846Relapsed/Refractory T-cell Lymphoma, Relapsed/Refractory Acute Myeloid Leukemia

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 1

Hangzhou

2024-12-01

Recruiting

Diagnosis Value of Interoceptive EEG Indicators by Rectal Stimulation in DoC

NCT07208942Disorders of Consciousness

YiLin Zhao

Observational

Hefei, Hangzhou

2024-12-01

Recruiting

A Study on the Efficacy of GD2-CAR T Cells in the Treatment of Neuroblastoma

NCT06684639Neuroblastoma

The General Hospital of Western Theater Command

Early Phase 1

Chengdu

2024-12-01

Not yet open

The Exploration of Personalized ctDNA Based MRD in the Clinical Significance of Cervical Cancer

NCT06283875Ovarian Cancer

Geneplus-Beijing Co. Ltd.

Observational

Suzhou

2024-12-01

By invitation

Clinical Study of Rhythmic Auditory Stimulation for Gait Disorders

NCT06837038Hemiplegia Due to Stroke, Parkinson Disease, Parkinsonian Syndrome

YiCheng Zhu

Not applicable

Beijing

2024-12-01

Recruiting

Safety and Efficacy of IMPT or IMRT for Breast Cancer

NCT06826885Breast Cancer, Proton Therapy, Intensity Modulated Radiation Therapy, Efficacy and Safety

Ruijin Hospital

Observational

500

Shanghai

2024-12-01

Recruiting

Retroperitoneal Tumor Registry

NCT07915895Retroperitoneal Neoplasms

The First Hospital of Jilin University

Observational

200

Changchun

2024-12-01

Recruiting

Prospective Study on the Safety and Efficacy of Robot-Assisted Laparoscopic Partial Nephrectomy With Renal Artery Off-Clamp in the Treatment of cT1 Renal Tumors

NCT06908902RCC, Renal Cell Cancer, Partial Nephrectomy

The First Affiliated Hospital with Nanjing Medical University

Not applicable

Nanjing

2024-12-01

Recruiting

A Prospective Study of ¹⁸F-DFA PET Imaging for the Assessment of Liver Injury

NCT07050550Liver Injury

First Affiliated Hospital of Zhejiang University

Observational

Hangzhou

2024-12-01

Not yet open

A Phase II Study of SHR-4602 as Montherapy or in Combination With Other Anti-tumor Therapies in Advanced Solid Tumors

NCT06704828Advanced Solid Tumors

DrugSHR-4602

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 2

Beijing

2024-12

Recruiting

VHAG in Treating R/R T-ALL/LBL

NCT06742463Acute T Lymphpblastic Leukemia/Lymphoma

DrugsHomoharringtonine·G-Csf·Ara-C·Cytarabine

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-12

Not yet open

Predicting Treatment Failure in HSIL Patients with Positive Margins After Conization Via Detection of PAX1 Methylation

NCT06713655High-grade Squamous Intraepithelial Lesions (HSIL), Cervical Conization

Women's Hospital School Of Medicine Zhejiang University

Observational

800

Hangzhou

2024-12

Not yet open

Study of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist（Diphenhydramine）in Advanced and Metastatic Non-Small Cell Lung Cancer

NCT06704620Advanced and Metastatic NSCLC

DrugsDiphenhydramine·Albumin paclitaxel·Pemetrexed·Tislelizumab

Tianjin Medical University Cancer Institute and Hospital

Phase 3

430

Tianjin

2024-12

Recruiting

CD147 Targeting Nanobody Probe for PET Imaging in Solid Tumors

NCT06646952Solid Tumor

DrugFluorodeoxyglucose

Hua Zhu

Observational

Beijing

2024-12

Recruiting

Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial

NCT06699433Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock, Hand-foot-and-mouth Disease, Acute Appendicitis

Southern Medical University, China

Not applicable

459

Guiyang, Fuzhou, Yisa

2024-12

Recruiting

Toripalimab Plus Actinomycin-D As Fist-Line Treatment for GTN with FIGO Score 7

NCT06020755Gestational Trophoblastic Neoplasia

DrugsActinomycin-D·Toripalimab

Peking Union Medical College Hospital

Phase 2

Beijing

2024-12

Not yet open

Clinical Study on the Treatment of Chronic Airway Diseases (Asthma, Chronic Obstructive Pulmonary Disease) with Shu Fei Tie

NCT06691802Chronic Obstructive Pulmoriary Disease (COPD), Asthma

Henan University of Traditional Chinese Medicine

Not applicable

2,312

Zhengzhou

2024-12

Not yet open

AK137 (Bispecific Antibody Targeting CD73 and LAG-3) in Patients With Advanced Malignant Tumors

NCT06691360Advanced Malignant Tumors

Akeso

Phase 1

Shanghai

2024-12

Not yet open

The Effectiveness of Pharmaceutical Service for INPATDRP

NCT06674512Drug Related Problem

Zhejiang Provincial People's Hospital

Not applicable

220

Hangzhou

2024-12

Not yet open

Study of Transcatheter Aortic Valve Replacement With A² Flex and Commissural Alignment Technology in Severe Aortic Stenosis

NCT06721676Aortic Stenosis Symptomatic

Peijia Medical Technology (Suzhou) Co., Ltd.

Not applicable

Suzhou

2024-12

Not yet open

SHR-1701 Combined with SHR2554 and BP102 for MCRC

NCT06679673Colorectal Cancer Metastatic

DrugsZeprumetostat·BP102·Retlirafusp alfa

Fudan University

Phase 2

Shanghai

2024-12

Not yet open

Research on the Monitoring, Pathogen Screening, and Diagnostic System for Unexplained and Newly Emerging Acute Hepatitis

NCT06653140Hepatitis of Unknown Aetiology

Minghui Li

Observational

100

Beijing

2024-12

Not yet open

Microbial Study of Sublingual Immunotherapy Spray in Patients With Allergic Rhinitis

NCT06741787Rhinitis, Allergic

The First Affiliated Hospital with Nanjing Medical University

Observational

100

Nanjing

2024-12

Not yet open

A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors

NCT06724263Recurrent Platinum-resistant Epithelial Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Cervical Cancers, Small Cell Lung Cancer

DrugB1962

Tasly Biopharmaceuticals Co., Ltd.

Phase 2

120

Shanghai

2024-12

Recruiting

Effect of Specific Mode Electroacupuncture Stimulation Combined with NGF on Dysphagia After Ischaemic Stroke: a Pilot Randomized Controlled Trial

NCT06737549Ischemic Stroke, Dysphagia

The Third Affiliated hospital of Zhejiang Chinese Medical University

Phase 4

144

Hangzhou

2024-12

Not yet open

Preoperative Tislelizumab -Cetuximab - Chemotherapy Followed by Salvage Surgery and Adjuvant Tislelizumab -Cetuximab for Resectable, Locally Recurrent Oral and Oropharyngeal Squamous Cell Carcinoma

NCT06728618Oral Squamous Cell Carcinoma (OSCC), Oropharyngeal Squamous Cell Carcinoma (SCC), Resectable Oral and Oropharyngeal Squamous Cell Carcinoma, Recurrent Oral and Oropharyngeal Squamous Cell Carcinoma

Shanghai Zhongshan Hospital

Phase 2

Shanghai

2024-12

Not yet open

A Study for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Brain and/or Spinal Cord Conditions

NCT06731829For Contrast-enhanced Magnetic Resonance Imaging (MRI) of Central Nervous System (CNS) Lesions

DrugGadobutrol

Jiangsu HengRui Medicine Co., Ltd.

Phase 2

Beijing

2024-12

Recruiting

Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALL

NCT06754267Precursor B-Cell Acute Lymphoblastic Leukemia

DrugsOlverembatinib·Venetoclax

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-12

Not yet open

Combined Aerobic Exercise and Cognitive Training in Seniors at Increased Risk for Alzheimer's Disease

NCT05163626Alzheimer Disease

Xuanwu Hospital, Beijing

Not applicable

200

Beijing

2024-12

Not yet open

JAK1 Inhibitor Ivarmacitinib Reversing Immunotherapy Resistance in TNBC

NCT06731153Triple Negative Breast Cancer (TNBC), Metastatic Breast Cancer

DrugsIvarmacitinib·Eribulin·Camrelizumab

Fudan University

Phase 2

Shanghai

2024-12

Not yet open

SHR-A1811 Combined with Apatinib in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer

NCT06666166Advanced Gastric Carcinoma, Advanced Gastroesophageal Junction Adenocarcinoma, Advanced Colorectal Cancer

Yunpeng Liu

Phase 2

Shenyang

2024-12

Not yet open

Study on Lipid Profile Changes in Plasma and Intestinal Mucosa of Patients With Inflammatory Bowel Disease

NCT06680076Inflammatory Bowel Diseases

First Affiliated Hospital of Harbin Medical University

Observational

Harbin

2024-12

Recruiting

PSA Versus STN DBS for DT

NCT06752434Dystonic Tremor

Ruijin Hospital

Not applicable

Shanghai

2024-12

Not yet open

Study on the Effect and Mechanism of Aescine Sodium in the Treatment of Allergic Rhinitis

NCT06709079Allergic Rhinitis

Cheng Lei

Not applicable

Nanjing

2024-12

Not yet open

Combined Aerobic Exercise and Cognitive Training in Seniors With Genetic Susceptibility for Alzheimer's Disease

NCT05163067Alzheimer Disease

Xuanwu Hospital, Beijing

Not applicable

200

Beijing

2024-12

Not yet open

Pralatrexate Combined With Chidamide Bridging Allogeneic HSCT for Refractory/Relapsed Peripheral T-cell Lymphoma

NCT06671717Relapsed Peripheral T-Cell Lymphoma, Refractory Peripheral T-Cell Lymphoma

Peking University People's Hospital

Not applicable

Beijing

2024-12

Recruiting

Long-term Safety and Tolerability of MY008211A Tablets in Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT06933914Paroxysmal Nocturnal Hemoglobinuria (PNH)

DrugMY008211A

Wuhan Createrna Science and Technology Co., Ltd

Phase 2/3

120

Tianjin

2024-11-30

Recruiting

Multi-cohort, Single-arm Phase II Study of Albumin-paclitaxel, Ifosfamide, and Cisplatin in the Treatment of Rare Advanced Tumors

NCT06684327Paget Disease, Extramammary, Rhabdomyosarcoma, Testicular Cancer, Penile Cancer

DrugAlbumin paclitaxel

Fudan University

Phase 2

100

Shanghai

2024-11-30

Not yet open

Third-generation EGFR-TKI Plus Anlotinib as Maintenance for NSCLC With Small Cell Transformation After EGFR-TKI Resistance

NCT06634667Non-small Cell Lung Cancer

DrugsThird-generation EGFR-TKI·Anlotinib

Hunan Province Tumor Hospital

Phase 2

Changsha

2024-11-30

Not yet open

Oral Topotecan With Toripalimab for Patients With Endometrial Cancer

NCT06548763Endometrial Cancer

DrugsTopotecan·Toripalimab

Fudan University

Phase 2

Shanghai

2024-11-30

Recruiting

Temporal Interference for Drug Resistant Epilepsy

NCT06708143Drug Resistant Epilepsy

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-30

Recruiting

The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever

NCT06682416Epidural Related Maternal Fever, Analgesia, Epidural, Fever, Intrapartum Fever

The First Affiliated Hospital of Soochow University

Not applicable

424

Suzhou

2024-11-30

Recruiting

Targeted Resection of Axillary Metastatic Lymph Nodes After Breast Cancer Neoadjuvant Chemotherapy

NCT04744506Breast Cancer, Surgery, Lymph Node Metastases

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

126

Hangzhou

2024-11-30

Recruiting

Efficacy and Safety of Additive Manufacturing Personalized Titanium Mesh in Guided Bone Regeneration

NCT06692244Alveolar Bone Atrophy, Guided Bone Regeneration

Hospital of Stomatology, Sun Yat-Sen University

Not applicable

142

Guangzhou

2024-11-30

Recruiting

Neoadjuvant Immunotherapy Plus Chemotherapy Followed by Concurrent Chemoradiotherapy and Consolidative Immunotherapy for Locally Advanced Non-small Cell Lung Cancer

NCT06734702Neoadjuvant Therapy, Concurrent Chemoradiotherapy, Immunotherapy, Locally Advanced Non-Small Cell Lung Cancer

Sun Yat-sen University

Phase 3

497

Guangzhou

2024-11-30

Not yet open

Mecapegfilgrastim Combined With Adebrelimab and Chemotherapy as Neoadjuvant Therapy in Resectable GC/GEJC

NCT06684158GC/GEJC

DrugsMecapegfilgrastim·Leucovorin·Adebrelimab·Adrucil

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2024-11-30

Recruiting

Concurrent Chemoradiotherapy Combined With Toripalimab and Surufatinib in the Treatment of Limited-Stage Small Cell Lung Cancer

NCT06719700Toripalimab, Surufatinib, Chemoradiotherapy, Limited-stage Small Cell Lung Cancer (LS-SCLC)

Sun Yat-sen University

Phase 2

Guangzhou

2024-11-30

Recruiting

Different Doses of Sirolimus for the Treatment of Cystic Lymphatic Malformations

NCT06673290Lymphatic Malformation

DrugsRapamycin·Sirolimus

West China Hospital

Phase 2/3

150

Chengdu

2024-11-30

Recruiting

The Value of 68Ga-FAPI PET/CT in Preoperative Evaluation of Thyroid Cancer with Lymph Node Metastases

NCT06730529Thyroid Cancer

Ruijin Hospital

Observational

Shanghai

2024-11-29

Active, closed

Safety and Efficacy of the Surpass Evolve Flow Diverter in Treating Intracranial Aneurysms

NCT06731946Intracranial Arterial Aneurysm

Yibin Fang

Observational

150

Shanghai

2024-11-29

Active, closed

A Study of SHR-A2009 Versus Platinum-based Chemotherapy in EGFR-mutated, Advanced or Metastatic NSCLC

NCT06671379Non-small Cell Lung Cancer

DrugSHR-A2009

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 3

498

Guangzhou

2024-11-29

Recruiting

Single-arm Clinical Trial of TACE in Combination With Icaritin as Adjuvant Therapy After Surgery in Patients With Hepatocellular Carcinoma at High Risk of Recurrence

NCT06644937Hepatocellular Carcinoma (HCC)

DrugTACE

Zhujiang Hospital

Phase 2/3

Guangzhou

2024-11-29

Recruiting

Efficacy and Safety of Low-dose Conbercept for Retinopathy of Prematurity Therapy

NCT06717412Retinopathy of Prematurity (ROP)

DrugConbercept

Wang Yusheng

Not applicable

146

Xi'an, Xianyang

2024-11-29

Recruiting

Exploratory Study on Infection and Immunosenescence Based on an Elderly Clinical Cohort

NCT07672522Immunosenescence

Huashan Hospital

Observational

484

Shanghai

2024-11-29

Recruiting

The Safety and Efficacy of Coenzyme I for Injection in Promoting Hematopoietic Recovery of Patients After sUCBT

NCT06558253Hematopoietic Recovery

DrugCoenzyme I

Anhui Provincial Hospital

Phase 1

Hefei

2024-11-29

Recruiting

SBRT, Chemotherapy, and AK112 Neoadjuvant Therapy for Luminal-type Breast Cancer

NCT06402435Breast Cancer

DrugIvonescimab

Hubei Cancer Hospital

Phase 2

Wuhan

2024-11-28

Recruiting

Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer

NCT06459687Cervical Cancer

DrugsCisplatin/Carboplatin·Paclitaxel·Bevacizumab

Lee's Pharmaceutical Limited

Phase 3

440

Hefei, Beijing, Wuhan, Changsha, Hangzhou

2024-11-28

Active, closed

A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China

NCT06666855Open Angle Glaucoma, Ocular Hypertension

Santen Pharmaceutical Co., Ltd.

Phase 3

345

Beijing, Guangzhou, Guiyang, Hangzhou, Heilongjiang, Jinan, Lanzhou, Luoyang

2024-11-28

Active, closed

Oncological Safety of Spleen Preservation in Left Pancreatectomy for Pancreatic Ductal Adenocarcinoma (SPLENDID)

NCT07157605Pancreatic Cancer Resectable, Pancreatectomy

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Observational

Nanjing

2024-11-28

Recruiting

SBRT, Chemotherapy, and AK104 Neoadjuvant Therapy for Triple-negative Breast Cancer (TNBC)

NCT06401005Breast Cancer

DrugCadonilimab

Hubei Cancer Hospital

Phase 2

Wuhan

2024-11-28

Recruiting

A Clinical Study of TQB2029 for Injection in Subjects With Multiple Myeloma

NCT06700395Multiple Myeloma

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 1

136

Shanghai, Chengdu

2024-11-28

Active, closed

Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities

NCT04077086Refractive Errors

Queen's University, Belfast

Not applicable

10,000

Shenyang, Yinchuan

2024-11-28

Recruiting

CD70-targeted immunoPET Imaging of Kidney Cancer

NCT06680089Urologic Neoplasms, Urogenital Neoplasms, Kidney Neoplasms, Neoplasms

Drug[18F]RCCB6

RenJi Hospital

Phase 2

300

Shanghai

2024-11-27

Active, closed

A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients

NCT06712771Homozygous Familial Hypercholesterolemia (HoFH)

DrugZodasiran

Visirna Therapeutics HK Limited

Phase 3

Beijing

2024-11-27

Recruiting

A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

NCT06634589B-cell Malignancy, Relapsed Cancer, Refractory Cancer, B-cell Lymphoma

DrugsTacabrutideg·Mosunetuzumab·Sonrotoclax·Glofitamab

BeOne Medicines

Phase 1/2

Fuzhou, Guangzhou, Suzhou, Hangzhou, Wenzhou

2024-11-27

Recruiting

Fluzoparib With or Without Bevacizumab for Neoadjuvant Therapy in Advanced Ovarian Cancer

NCT06735326Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer

DrugsFluzoparib·Paclitaxel·Bevacizumab·Carboplatin

Qilu Hospital of Shandong University

Phase 2

105

Jinan

2024-11-27

Recruiting

A Phase I Study to Investigate the Safety and Tolerability of KGX101 Monotherapy and Combination Therapy With Envafolimab in Advanced or Metastatic Solid Tumor Patients

NCT07260305Advanced or Metastatic Solid Tumors

DrugsKGX101·Envafolimab

Kangabio AUSTRALIA LTD PTY

Phase 1

Beijing, Shanghai

2024-11-27

Recruiting

A Phase III Study Comparing Taletrectinib With Standard Therapy in ROS1 Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients

NCT06564324Non Small Cell Lung Cancer

DrugsTaletrectinib·Crizotinib

Nuvation Bio Inc.

Phase 3

194

Hefei, Beijing, Chongqing, Xiamen, Guangzhou, Nanning, Shijiazhuang, Zhengzhou

2024-11-27

Active, closed

A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

NCT06670196Non-Small Cell Lung Cancer

DrugsSacituzumab tirumotecan·Osimertinib

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Phase 3

420

Guangzhou

2024-11-27

Recruiting

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

NCT06526793B-cell Non-Hodgkin Lymphoma, Follicular Lymphoma (FL), Large B-Cell Lymphoma (LBCL)

DrugSurovatamig

AstraZeneca

Phase 2

270

Chengdu, Guangzhou, Nanchang, Nanjing, Nantong, Shandong, Shanghai, Tianjin

2024-11-27

Recruiting

The Changes Under Different Accommodation of Anterior Eye and 3D Crystal Reconstruction.

NCT06704503Accommodation

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

120

Hangzhou

2024-11-27

Recruiting

Radiotherapy Combined With Fluzopanib and Abiraterone Acetate Tablets (II) Treatment for mCRPC

NCT06971211Metastatic Castration-resistant Prostate Cancer

DrugIMRT

Jianbin Bi

Phase 2

Shenyang

2024-11-27

Recruiting

Nab-TPC vs GP Combined With Camrelizumab in the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma

NCT06669611Nasopharyngeal Cancinoma (NPC)

Sun Yat-sen University

Phase 3

242

Guangzhou

2024-11-27

Recruiting

A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes

NCT06712680Solid Tumor

DrugOsimertinib

Sichuan Huiyu Pharmaceutical Co., Ltd

Phase 1/2

115

Guangzhou

2024-11-27

Recruiting

Study on the Application of Intraoperative Optical Coherence Tomography Technique in the Diagnosis and Treatment of Lens Diseases

NCT06687356Lens Diseases

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

600

Hangzhou

2024-11-27

Recruiting

Study of Pazopanib Combined With Palbociclib for Refractory Solid Tumors With Co-amplified in the 11q13(FGF3/4/19/CCND1)

NCT06895733Solid Tumor, Adult, Next-generation Sequencing, Precision Medicine

DrugsPazopanib·Palbociclib

Tianjin Medical University Second Hospital

Phase 1/2

Tianjin

2024-11-27

Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

NCT06627647Non-squamous Non-small Cell Lung Cancer

DrugsRilvegostomig·Pemetrexed·Keytruda·Cisplatin

AstraZeneca

Phase 3

1,160

Beijing, Changchun, Changsha, Chengdu, Chongqing, Fuzhou, Guangzhou, Hangzhou

2024-11-27

Active, closed

Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BDLL Chinese Cohort

NCT06649721Drug-resistant Tuberculosis, Pulmonary Tuberculosis, Rifampin-resistant Tuberculosis

DrugsClofazimine·Delamanid·Bedaquiline·Levofloxacin

Huashan Hospital

Phase 3

120

Hefei, Beijing, Xiamen, Nanning, Liupanshui, Shijiazhuang, Harbin, Jiamusi

2024-11-27

Active, closed

A Randomized Controlled Trial to Improve the Therapeutic Effect of Robot-assisted Radical Prostatectomy (RARP) Using Indocyanine Green Fluorescence Imaging

NCT06748742Prostate CA

Liu Cheng

Observational

Shanghai

2024-11-26

By invitation

Evaluating the Safety and Efficacy of BioTTT001 in Patients With Recurrent/Progressive High-grade Glioma.

NCT06763965Recurrent High-grade Glioma

DrugBioTTT001

Beijing Bio-Targeting Therapeutics Technology Co., Ltd

Phase 1/2

Beijing

2024-11-26

Recruiting

Multicenter, Phase I/II Study to Evaluate the Safety, Tolerability, PK and Efficacy of SCT520FF in Patients With nAMD

NCT06672536nAMD

DrugEylea

Sinocelltech Ltd.

Phase 1/2

Tianjing

2024-11-26

Recruiting

DCE-MRI Based on 4D Free Breathing for Predicting Preoperative Neoadjuvant Chemoradiotherapy for Esophageal Cancer

NCT06755866Esophageal Cancer

Yunnan Cancer Hospital

Not applicable

135

Kunming

2024-11-26

Not yet open

Induced Pluripotent Stem Cells Derived Natural Killer Cells Therapy for Refractory and Relaps Acute Myelogenous Leukemia

NCT06702098Acute Myeloid Leukemia (AML)

Guangzhou Ruixin Biotechnological Co., LTD

Early Phase 1

Guangzhou

2024-11-25

Recruiting

Efficacy and Safety of Minimally Invasive D2+PAND Gastrectomy for Gastric Cancer With PAN Metastasis After Conversion Immunochemotherapy

NCT07056010Gastric Cancer

The First Affiliated Hospital with Nanjing Medical University

Not applicable

Nanjing

2024-11-25

Recruiting

Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose Tolerance

NCT06684106Hyperlipidemia, Ursodeoxycholic Acid, Statin Therapy, Glucose Intolerance

DrugUDCA

First Affiliated Hospital Xi'an Jiaotong University

Not applicable

128

Xi'an

2024-11-25

Recruiting

A Phase 2 Clinical Study of Combination Therapy With ABSK043 and Firmonertinib

NCT06668103Non-Small Cell Lung Cancer With EGFR Mutation

DrugsABSK043·Furmonertinib

Abbisko Therapeutics Co, Ltd

Phase 2

Hefei, Harbin, Wuhan, Changchun, Shanghai

2024-11-25

Recruiting

A Study of ES014 in Subjects With Advanced Solid Tumors

NCT06543056Advanced Solid Tumor

DrugES014

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 2

Beijing

2024-11-25

Recruiting

Atrial Shunt for the Treatment of Heart Failure With Reduced Ejection Fraction

NCT07820410Heart Failure With Reduced Ejection Fraction (HFrEF)

Beijing Anzhen Hospital

Phase 2/3

208

Beijing

2024-11-25

Recruiting

The Effect of Different Digestive Tract Reconstruction Methods on Postoperative Quality of Life After Proximal Gastrectomy

NCT06929949Gastroesophageal Junction (GEJ) Cancer, Gastric Cancer

The First Hospital of Jilin University

Observational

Changchun

2024-11-25

Not yet open

Anlotinib Plus Nab-Paclitaxels and S-1 for Patients with Advanced Biliary Tract Cancer As Second-Line Treatment

NCT06662877Biliary Tract Cancer, Second Line Treatment, Chemotherapy, Tyrosine Kinase Inhibitor

DrugsTegafur Gimeracil Oteracil·Albumin-Bound Paclitaxel·Teysuno·Anlotinib

Sun Yat-sen University

Phase 2/3

206

Guangzhou

2024-11-25

Recruiting

Safety, Tolerability, and Pharmacokinetics of Single Doses of HC022 in Healthy Subjects.

NCT06657703Systemic Lupus Erythematosus

DrugHC022

HC Biopharma Inc.

Phase 1

Beijing

2024-11-25

Recruiting

Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases

NCT06688799Autoimmune Diseases

Beijing GoBroad Hospital

Phase 1/2

Beijing

2024-11-23

Recruiting

Vitamin C Plus Cordyceps to Chemotherapy Related Anemia in Pancreatic Cancer

NCT06601283Pancreatic Cancer

Fudan University

Phase 2/3

Shanghai

2024-11-22

Recruiting

SHR-A1904 Compared With Investigator's Choice of Therapy in Claudin18.2 Positive Patitens With Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

NCT06649292Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

DrugsPaclitaxel, Docetaxel, Irinotecan·SHR-A1904

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 3

524

Guangzhou

2024-11-22

Active, closed

A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps

NCT06639295Sinusitis, Nasal Polyps

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

Phase 3

243

Beijing

2024-11-22

Recruiting

Clinical Prediction Model for In-Hospital Rebleeding in Acute Non-Variceal Upper Gastrointestinal Bleeding

NCT06697691Acute Non-variceal Upper Gastrointestinal Bleeding

Junwei Yan

Observational

1,000

Wuhan

2024-11-22

Recruiting

Vitamin C Plus Cordyceps to Quality of Life in Patients With Terminal Stage Pancreatic Cancer

NCT06598033Pancreatic Cancer

Fudan University

Phase 2/3

Shanghai

2024-11-22

Recruiting

The Trend of Copeptin Levels and Its Clinical Value for Postoperative CDI in Pediatric Patients After NSI in ICU

NCT06742060Diabetes Insipidus, Neurohypophyseal, Copeptin Blood Levels, Copeptin, Neurosurgical Intervention

Children's Hospital of Fudan University

Observational

100

Shanghai

2024-11-22

Recruiting

A Phase I/IIa Study of JAB-23E73 in Patients With Advanced Solid Tumors Harboring KRAS Gene Alteration

NCT06959615Advanced Solid Tumor

DrugJAB-23E73

Jacobio Pharmaceuticals Co., Ltd.

Phase 1/2

334

Hefei, Beijing, Fuzhou, Guangzhou, Nanning, Langfang, Haerbin, Zhengzhou

2024-11-22

Recruiting

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

NCT06532006Gastroesophageal-junction Cancer, Monoclonal Antibody, Gastric Cancer, HER2-positive Gastric Cancer

DrugsHLX22·Trastuzumab·Capecitabine·Oxaliplatin

Shanghai Henlius Biotech

Phase 3

550

Baise City, Beijing, Bengbu, Changchun, Changsha, Changzhi, Changzhou, Chengdu

2024-11-22

Active, closed

Small/Middle Tier Cities and County Lung Cancer Quality Improvement Project (QIP) Study

NCT06494241Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Respiratory Tract Neoplasms, Thoracic Neoplasms

AstraZeneca

Observational

1,000

Anning, Anqing, Changzhi, Daqing, Dazhou, Dazhu, Dingzhou, Ganzhou

2024-11-22

Recruiting

nTMS for Negative Symptom in Schizophrenia

NCT06642675Schizophrenia

Central South University

Not applicable

Changsha

2024-11-22

Recruiting

The EEG Study Under Remimazolam Anesthesia in Children

NCT06698705Electroencephalography, Remimazolam, Child Neglect

Second Affiliated Hospital of Wenzhou Medical University

Observational

Wenzhou

2024-11-22

Recruiting

A Study of EH002 Gene Therapy for Otoferlin Gene Mutation-mediated Hearing Loss

NCT06722170DFNB9, Congenital Hearing Loss, Hearing Loss, Sensorineural

Yilai Shu

Not applicable

Zhengzhou, Shanghai

2024-11-22

Recruiting

Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors

NCT06666270Advanced Solid Cancer, Metastatic Solid Tumor, Ovarian Cancer, Breast Cancer

Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd

Phase 1

Zhengzhou, Shanghai

2024-11-21

Recruiting

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

NCT06617325Systemic Lupus Erythematosus

UCB Biopharma SRL

Phase 3

450

Baotou, Beijing, Bengbu, Changchun, Changsha, Changzhou, Chengdu, Guangzhou

2024-11-21

Recruiting

A Study of HRS-4642 Monotherapy or in Combination With Adebrelimab in the Treatment of Advanced Biliary Tract Tumors.

NCT06620848Biliary Tract Cancer

DrugHRS-4642

Shanghai Zhongshan Hospital

Phase 2

Shanghai

2024-11-21

Active, closed

Camrelizumab Combined With or Without Apatinib and SOX of Neoadjuvant Treatment for Gastric Cancer

NCT06693128Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma

DrugsS-1, Oxaliplatin·Apatinib·Camrelizumab

Ruijin Hospital

Phase 2

Chengdu, Shanghai, Yantai

2024-11-21

Active, closed

A Clinical Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) to Treat Newly-diagnosed Metastatic Non-small Cell Lung Cancer (MK-3475A-F84)

NCT06698042Lung Cancer, Non-Small Cell Lung Cancer

Drugs) Berahyaluronidase alfa·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

Beijing, Chongqing, Fuzhou, Xiamen, Guangzhou, Huizhou, Jiangmen, Liuzhou

2024-11-21

Recruiting

Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases

NCT06671236Amyotrophic Lateral Sclerosis (ALS)

Novabio Therapeutics

Phase 1

Zhengzhou

2024-11-21

Recruiting

A Clinical Trial Evaluating TQB2102 for Injection in Combination With Behmosubaisumab/Payamprolizumab With or Without Chemotherapy in Unresectable Locally Advanced, Recurrent, or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastroesophageal Adenocarcinoma

NCT06767800Gastroesophageal Adenocarcinoma

DrugsTQB2102·Penpulimab·Benmelstobart

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 2

204

Fuyang, Lu'an, Maanshan, Beijing, Chongqing, Fuzhou, Lanzhou, Wuwei

2024-11-21

Recruiting

Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal Hypertension

NCT06669806Portal Hypertension Related to Cirrhosis, Ascites Hepatic, Variceal Bleeding

C. R. Bard

Not applicable

166

Changsha

2024-11-21

Active, closed

A Multi-centered，Randomized，Double-blind，Placebo-controlled Study to Evaluate the Efficacy and Safety of SHR-1703 in Eosinophilic Asthma

NCT06653322Asthma With Eosinophilic Phenotype

Guangdong Hengrui Pharmaceutical Co., Ltd

Phase 3

401

Chengdu

2024-11-21

Recruiting

Dolasetron for the Prevention of CINV in Children With Acute Lymphoblastic Leukemia

NCT06756022Chemotherapy Induced Nausea and Vomiting

Anhui Provincial Children's Hospital

Observational

500

Hefei

2024-11-21

Recruiting

Radiolabelled Nectin-4 Targeted LMW Probe PET/CT in Patients With Lung Lesions

NCT06648317Lung Cancer, Non-Small Cell, Lung Infection

Peking University Cancer Hospital & Institute

Observational

Beijing

2024-11-21

Recruiting

Evaluation of Rovadicitinib Compared to the Protocol Selected by Researchers in Third Line and Subsequent Studies of Moderate to Severe Chronic Graft-versus-host Disease

NCT06682169Graft-versus-host Disease

DrugsRovadicitinib·Mycophenolate Mofetil·Imatinib·Methotrexate

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 3

182

Hefei, Beijing, Chongqing, Fuzhou, Xiamen, Lanzhou, Guangzhou, Nanning

2024-11-20

Recruiting

Perioperative Tislelizumab for Resectable II-IIIB(N2) KRAS-mutated Nonsquamous Non-small Cell Lung Cancer

NCT06659042Lung Cancer, Non-Small Cell

DrugsPemetrexed·Tislelizumab·Cisplatin·Carboplatin

Shanghai Chest Hospital

Phase 2

Shanghai

2024-11-20

By invitation

Haemodialysis Alters Hypercoagulability of Blood in Dialysis Patients

NCT07098676Healthy Individuals (Controls), Vascular Surgery Patients With Acute Thrombosis, Dialysis Patients

Ai Peng

Observational

900

Shanghai

2024-11-20

Recruiting

A Prospective Clinical Study of the Combination Therapy of Obutinib or Decitabine with Rituximab, Cyclophosphamide, and Prednisone for the Primary Treatment of Elderly Patients with Newly Diagnosed Diffuse Large B-cell Lymphoma

NCT06683885Newly Diagnosed Diffuse Large B-cell Lymphoma

Mingzhi Zhang

Phase 1/2

Zhengzhou

2024-11-20

Recruiting

Study on Aging and Cognitive Impairment in China

NCT06679296Cognitive Dysfunction, Aging

First Affiliated Hospital of Wenzhou Medical University

Observational

20,000

Wenzhou

2024-11-20

Recruiting

Immunobridging/Maintenance Therapy Versus Non-bridging Therapy in CAR-T Therapy for Low-risk R/R B-NHL

NCT06695013B-NHL, CART Therapy

DrugsCar-T·Zanubrutinib·Tislelizumab

Ruijin Hospital

Phase 2

144

Shanghai

2024-11-20

Not yet open

Qishenyiqi for Ventricular Remodeling After Myocardial Infarction

NCT06699407Chronic Stable Heart Failure

Qilu Hospital of Shandong University

Phase 4

210

Jinan

2024-11-20

Recruiting

Cryoablation Plus Camrelizumab for Advanced Soft Tissue Sarcoma

NCT07602049Soft Tissue Sarcoma (STS), Osteosarcoma

Sun Yat-sen University

Phase 2

Guangzhou

2024-11-20

Recruiting

Analysis of 18F-XTR006 PET Imaging in Cognitively Normal Subjects, and Patients With MCI and AD

NCT07115238Alzheimer Disease, Neurofibrillary Tangle

Sinotau Pharmaceutical Group

Phase 3

354

Beijing

2024-11-20

Recruiting

The Treatment of Sepsis Induced Myocardial Dysfunction With Yiqilishui Formula

NCT06686355Sepsis Induced Myocardial Dysfunction

Dongzhimen Hospital, Beijing

Phase 2

Beijing

2024-11-20

Recruiting

The Safety and Efficacy of Robotic Assisted Surgery Using Vessel Sealer Extend in Locally Advanced Gastric Cancer

NCT06881043Locally Advanced Gastric Cancer, Gastric Adenocarcinoma

The First Hospital of Jilin University

Observational

300

Changchun

2024-11-20

Recruiting

Micturition Desire-Relaxation Training Device for Lower Urinary Tract Dysfunction in Children

NCT07000656Daytime Urinary Incontinence, Urinary Frequency, Lower Urinary Tract Dysfunction, Primary Nocturnal Enuresis

Shanghai Children's Medical Center

Not applicable

200

Shanghai

2024-11-20

Recruiting

Low Dose Radiotherapy Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Stage II-III NSCLC

NCT06714708NSCLC, Neoadjuvant Immunotherapy, Low Dose Radiotherapy, Sintilimab

Anhui Provincial Cancer Hospital

Phase 2

Hefei

2024-11-20

Not yet open

Washed Microbiota Transplantation in Solid Organ Transplantation

NCT06708676Solid Organ Transplant Complications

The Second Hospital of Nanjing Medical University

Not applicable

Nanjing

2024-11-20

Recruiting

A Survey on Growth Development in Children After Liver Transplantation

NCT07574398Growth, Development in Pediatric Liver Transplant Recipients

RenJi Hospital

Observational

275

Shanghai

2024-11-20

Recruiting

Glucocorticoids Combined With Concurrent Chemoradiotherapy for Unresectable Thymoma

NCT06730308Thymoma

DrugMethylprednisolone

Sun Yat-sen University

Phase 2

Guanzhou

2024-11-20

Recruiting

WHO Mental Health Gap Action Program (mhGAP) for Improving Child Mental and Behavioral Disorder Service Quality in China

NCT06702410Neurodevelopmental Disorders

Sun Yat-sen University

Not applicable

375

Zhongshan

2024-11-20

Recruiting

ImmunoPET Imaging of Pancreatic Cancer

NCT06602037Neoplasms Pancreatic

RenJi Hospital

Not applicable

Shanghai

2024-11-20

Recruiting

Ivonescimab in the Treatment of Multiple Advanced Tumors

NCT06683846Pheochromocytoma/Paraganglioma, Rhabdomyosarcoma, Paget Disease, Extramammary, Renal Angiomyolipoma

Fudan University

Phase 2

400

Shanghai

2024-11-20

Recruiting

Pharmacokinetic Study of Tranexamic Acid

NCT06728670Ovarian Neoplasm Epithelial

Zhejiang Cancer Hospital

Not applicable

Hangzhou

2024-11-20

Recruiting

Efficacy and Safety of Peginterferon in ET and PV.

NCT06734637Essential Thrombocythemia, Polycythemia Vera

DrugPeginterferon α-2b

Zhenya Hong

Not applicable

Wuhan

2024-11-20

Recruiting

Effects of Low Tidal Volume and Airway Pressure Release Ventilation on Lung Tissue Mechanics in ARDS Patients Under Mechanical Ventilation: A Prospective Randomized Crossover Study

NCT06790875ARDS (Acute Respiratory Distress Syndrome)

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Not applicable

Wuhan

2024-11-20

Recruiting

Firmonertinib Versus Platinum Based Chemotherapy as First-line Treatment for NSCLC With EGFR PACC or EGFR l861q Mutation

NCT06956001EGFR, NSCLC (Advanced Non-small Cell Lung Cancer)

DrugsFirmonertinib Mesilate·Pemetrexed·Cisplatin·Carboplatin

Allist Pharmaceuticals, Inc.

Phase 3

300

Beijing, Shandong

2024-11-19

Recruiting

Serplulimab With Chemoradiotherapy for Postoperative Cervical Cancer With Risk Factors

NCT06727617Cervical Cancers

DrugSerplulimab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

134

Tianjin

2024-11-19

Recruiting

Selective Neck Dissection Versus Modified Neck Dissection in PTC

NCT06554652Thyroid Cancer

Fudan University

Phase 3

250

Shanghai

2024-11-19

Recruiting

A Deep Learning Model for Diagnosing Lymph Node Metastasis in Nasopharyngeal Carcinoma(NPC)

NCT06829147Nasopharyngeal Cancinoma (NPC), Lymph Node Metastasis

Sun Yat-sen University

Observational

500

Guangzhou

2024-11-19

Recruiting

Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in ICU Patients

NCT06702813Atelectasis, Postoperative, Hypoxia, Critical Illness

Shanghai Zhongshan Hospital

Not applicable

Shanghai

2024-11-19

Recruiting

Underdilated-stent Technique Improves Post-TIPS Encephalopathy

NCT07349654Liver Cirrhosis, Variceal Bleeding, Cirrhosis, Ascites Hepatic, Hepatic Encephalopathy (HE)

The Second Affiliated Hospital of Chongqing Medical University

Not applicable

Chongqing, Qianjiang

2024-11-19

Active, closed

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

NCT06578247Leukemia

DrugQuizartinib

Daiichi Sankyo

Phase 3

700

Beijing, Changchun, Changsha, Chongqing, Guangzhou, Jinan, Nanchang, Nanjing

2024-11-19

Recruiting

Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study

NCT07020247Locally Advanced Rectal Cancer (LARC), Immunotherapy, Radiotherapy, Total Neoadjuvant Therapy

West China Hospital

Phase 3

184

Chengdu

2024-11-19

Recruiting

Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery

NCT06361238Delirium, Postoperative

DrugLiraglutide

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 3

260

Nanjing

2024-11-19

Recruiting

Moderated Hypofractionated Online Adaptive Radiotherapy in Cervical Cancer

NCT06641635Cervical Cancer, Adaptive Radiotherapy

Peking Union Medical College Hospital

Phase 3

440

Beijing

2024-11-19

Recruiting

An Exploratory Study of Tislelizumab in Combination with Chemotherapy in Immuno-experienced Patients with EGFR/ALK/ROS1-negative Advanced NSCLC in the Second-line Setting

NCT06749886Lung Cancer

DrugsDenosumab·Tislelizumab·Docetaxel

Shanghai Pulmonary Hospital, Shanghai, China

Phase 2

Shanghai

2024-11-19

Recruiting

Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma

NCT06652243Hepatocellular Carcinoma (HCC)

DrugsFludarabine·Cyclophosphamide

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Early Phase 1

Shanghai

2024-11-18

Recruiting

Evaluation of Two Cell-based Assays for Diagnosing MOG-IgG Associated Disorders

NCT06617962Myelin Oligodendrocyte Glycoprotein (MOG)-Antibody Related Disorders

Huashan Hospital

Observational

240

Shanghai

2024-11-18

Recruiting

Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Hepatocellular Carcinoma Recurrence Surveillance

NCT06653062Hepatocellular Carcinoma (HCC)

Tongji Hospital

Observational

Wuhan

2024-11-18

Recruiting

Venetoclax-Azacitidine in Combination With Chidamide and CAG in Fit Older Patients With Acute Myeloid Leukaemia

NCT07514936Newly Diagnosed Acute Myeloid Leukemia (AML), Elderly Patients

DrugsAclacinomycin·Azacytidine·Chidamide·Cytarabine

Chinese PLA General Hospital

Phase 3

120

Beijing

2024-11-18

Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

NCT06692738Non-small Cell Lung Cancer

DrugsRilvegostomig·Nab-paclitaxel·Keytruda·Paclitaxel

AstraZeneca

Phase 3

1,160

Beijing, Changchun, Changde, Changsha, Chengdu, Chongqing, Dalian, Guangzhou

2024-11-18

Recruiting

Neoadjuvant Chemoradiotherapy Compared to Neoadjuvant Chemotherapy for Luminal-Type Locally Advanced Breast Cancer: A Clinical Study

NCT06697938Breast Cancer

Sichuan Cancer Hospital and Research Institute

Not applicable

148

Chengdu

2024-11-18

Recruiting

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

NCT06672549Obesity, Overweight

DrugOrforglipron

Eli Lilly and Company

Phase 3

125

Tainan, Taipei, Taoyuan

2024-11-18

Recruiting

Mts105 for Advanced Hepatocellular Carcinoma

NCT06689540Liver Cancer, Adult, Metastatic Liver Cancers, HCC - Hepatocellular Carcinoma, Hepatocellular Carcinoma (HCC)

Shen Lin

Phase 1

Beijing

2024-11-18

Recruiting

NKG2D/CLDN18.21 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumor

NCT06134960Gastric Cancer, Pancreatic Cancer, Solid Tumor

Peking University

Phase 1

Beijing

2024-11-16

Recruiting

Exploring the Efficacy and Safety of Tislelizumab in Combination With S-1 in the Treatment of Patients With Postoperative Recurrent High-risk Intrahepatic Cholangiocarcinoma

NCT06664021Intrahepatic Cholangiocarcinoma

DrugsTeysuno·Tislelizumab

Anhui Provincial Hospital

Phase 2

Fuyang, Hefei

2024-11-16

Recruiting

Tissue-resident Immune Cell Subsets in aGVHD

NCT06708507Acute Graft-versus-Host Disease, Hematopoietic Stem Cell Transplantation

Nanfang Hospital, Southern Medical University

Observational

Guangzhou

2024-11-16

Recruiting

A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia

NCT06568471Hypercholesterolemia, Dyslipidemias, Primary Hypercholesterolemia, Heterozygous Familial Hypercholesterolemia

DrugLerodalcibep

Hasten Biopharmaceutical Co., Ltd.

Phase 3

210

Beijing, Guangzhou, Shijiazhuang, Daqing, Changsha, Nanchang, Binzhou, Heze

2024-11-16

Recruiting

AK112 Combined With Chemotherapy as the First-line Treatment in Advanced Esophageal Squamous Cell Carcinoma Patients

NCT06489197ESCC, Advanced Esophageal Squamous Cell Carcinoma

DrugIvonescimab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-11-16

Recruiting

Art Therapy and Its Effect on Motor Function Rehabilitation in the Subacute Phase of Stroke Recovery

NCT06709950Stroke

Chonbuk National University

Not applicable

Jiamusi

2024-11-15

Recruiting

Study of Adjuvant Nimotuzumab Combined with Nab-paclitaxel+ Gemcitabine in EGFR-positive Pancreatic Cancer

NCT06722911Pancreatic Cancer Resectable

DrugNimotuzumab

Zhejiang Provincial People's Hospital

Phase 2

Hangzhou

2024-11-15

Recruiting

Donafenib Combined With Capecitabine for Postoperative Adjuvant Therapy of Biliary Malignant Tumors With High-risk Recurrence Risk

NCT06685289Biliary Malignant Tumors

DrugsDonafenib·Capecitabine

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2024-11-15

Active, closed

Clinical Trial of Lyophilized Haemophilus Influenzae Type b Conjugate Vaccine

NCT06621654Haemophilus Influenzae Type B Infection

CanSino Biologics Inc.

Phase 1

160

Chongqing

2024-11-15

Not yet open

EGFR Mutation Targeting Molecular Probe for PET Imaging

NCT06641674Cancer

Peking University Cancer Hospital & Institute

Observational

Beijing

2024-11-15

Recruiting

The Association Between Plasma Metabolites and the Risk, Efficacy and Prognosis in Early Breast Cancer

NCT06698679Breast Cancer

Shengjing Hospital

Observational

1,000

Shenyang

2024-11-15

Active, closed

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

NCT06616194Migraine

DrugRimegepant

Pfizer

Phase 3

636

Beijing, Chongqing, Guangzhou, Jingzhou, Wuhan, Changsha, Suzhou, Wuxi

2024-11-15

Recruiting

The Association of Psychological Stress with the Efficacy of Neoadjuvant Therapy in Breast Cancer

NCT06690645Breast Cancer

Shengjing Hospital

Observational

840

Shenyang

2024-11-15

Active, closed

Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction

NCT06576921Stomach Neoplasms, Immune Checkpoint Inhibitors

DrugsTeysuno·Serplulimab·Oxaliplatin

Xijing Hospital

Phase 2

116

Shijiazhuang, Xi'an, Tianjin

2024-11-15

Active, closed

Ultrasound-based Artificial Intelligence for Classification of Carpal Tunnel Syndrome

NCT06697392Carpal Tunnel Syndrome (CTS), Ultrasound, Artificial Intelligence (AI)

Peking University People's Hospital

Observational

500

Beijing

2024-11-15

Recruiting

Art Therapy and Its Effect on Non-Motor Function Rehabilitation in the Subacute Phase of Stroke Recovery

NCT06713252Stroke

Chonbuk National University

Not applicable

Jiamusi

2024-11-15

Not yet open

Post-market Clinical Follow-up Study Plan for Disposable Endoscopic Linear Cutter Stapler

NCT06677008The Expeditious Transection/resection of Tissues and Creation of Anastomoses

Suzhou Care-Real Medical Technology Co., Ltd.

Observational

302

Wujin District

2024-11-15

Recruiting

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

NCT06698757Colorectal Cancer

DrugSintilimab

Yugui Lian

Phase 2

Zheng'zhou

2024-11-15

Not yet open

Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients

NCT06665880Drug Resistant Epilepsy, Traumatic Brain Injury Without Open Intracranial Wound

Xuanwu Hospital, Beijing

Observational

Beijing

2024-11-15

Recruiting

Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Multicenter, Observational Study (IAT-CLOSURE)

NCT06548269Acute Ischemic Stroke, Atrial Fibrillation

Jinan Central Hospital

Observational

1,000

Jinan

2024-11-15

Recruiting

Bortezomib Combined with PD-1 MAb and MFOLFIRINOX for Metastatic Pancreatic Cancer

NCT06572813Pancreas Cancer

DrugsMFOLFIRINOX·Bortezomib·Sintilimab

First Affiliated Hospital of Zhejiang University

Phase 1/2

Hangzhou

2024-11-15

Recruiting

Effect of HCQ Combined With LT4 on LBR in Euthyroid Women With URPL and TPO-Ab

NCT06652113Recurrent Pregnancy Loss, Euthyroid With Thyroid Antibodies

DrugLevothyroxine

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not applicable

796

Guangzhou

2024-11-15

Recruiting

A Clinical Study of Personalized Self-DC Vaccine Targeting Neoantigen in Treatment of Advanced Solid Tumor

NCT06682117Treatment, Neoantigen, Vaccine, Solid Tumor Cancer

DrugDC Vaccine

Fudan University

Not applicable

Shanghai

2024-11-15

Recruiting

CD19 CAR-T in the Treatment of Relapsed/Refractory Autoimmune Diseases

NCT06680388Autoimmune Diseases

Institute of Hematology & Blood Diseases Hospital, China

Early Phase 1

Tianjin

2024-11-15

Recruiting

Efficacy, Safety and Immunological Evaluation of Upadacitinib for Relapsing Polychondritis

NCT06873100Relapsing Polychondritis

DrugUpadacitinib

Peking University People's Hospital

Phase 1/2

Beijing

2024-11-15

Not yet open

CAR-T Cell Therapy Targeting GPC3 in Patients with Advanced GPC3-Positive Hepatocellular Carcinoma

NCT06641453Hepatocellular Carcinoma (HCC)

DrugsFludarabine Phosphate·Cyclophosphamide

Chinese PLA General Hospital

Phase 1/2

Beijing

2024-11-15

Recruiting

Safety and Effectiveness of Early Aspirin Administration After Mitral Valve Repair

NCT06738992Mitral Valve Repair Surgery

DrugsWarfarin·Aspirin

Guangdong Provincial People's Hospital

Phase 4

384

Guangzhou

2024-11-14

Recruiting

The Clinical Trial of TQB2102 for Injection Against Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer

NCT06452706Breast Cancer

DrugTQB2102

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 2

Bozhou, Chuzhou, Hefei, Ma’anshan, Wuhu, Harbin, Zhengzhou, Wuhan

2024-11-14

Recruiting

Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL

NCT06880913Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Peking University People's Hospital

Phase 1/2

Beijing

2024-11-14

Recruiting

ICP-332 in Subjects With Moderate to Severe Atopic Dermatitis

NCT06775860Atopic Dermatitis

DrugICP-332

Beijing InnoCare Pharma Tech Co., Ltd.

Phase 3

552

Hefei, Wuhu, Beijing, Chongqing, Fuzhou, Xiamen, Guangzhou, Shaoguan

2024-11-14

Active, closed

Monitoring JE Antibody Levels in Healthy Populations and Immunization Strategy in Low-Prevalence Areas

NCT06678373Japanese Encephalitis

Liaoning Chengda Biotechnology CO., LTD

Phase 4

250

Shenyang

2024-11-14

Active, closed

A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia

NCT06637501Chronic Lymphocytic Leukemia

DrugsSonrotoclax·Zanubrutinib

BeOne Medicines

Phase 2

Fuzhou, Zhengzhou, Changzhou, Nanjing, Shanghai, Hangzhou

2024-11-14

Recruiting

"Xijiang Project" Screening Cohort for NPC

NCT06787456Nasopharyngeal Carcinoma (NPC), Screening

Ming-Yuan Chen

Observational

1,000,000

Zhuhai

2024-11-14

Recruiting

Robotic Gastrectomy for Locally Advanced Gastric Cancer After Neoadjuvant Therapy

NCT06895447Gastric Cancers

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2024-11-14

Active, closed

EPOCH-Economics and Patient Outcomes in China in Haemophilia

NCT07454239Hemophilia

Institute of Hematology & Blood Diseases Hospital, China

Observational

500

Tianjin

2024-11-14

Active, closed

A Study of SIM0270 Combined With Everolimus vs. Treatment of Physician's Choice in Patients With ER+/HER2- Advanced Breast Cancer (SIMRISE)

NCT06680921Locally Advanced or Metastatic Breast Cancer

DrugsSIM0270·Exemestane·Everolimus·Fulvestrant

Jiangsu Simcere Pharmaceutical Co., Ltd.

Phase 3

482

Bengbu, Hefei, Maanshan, Beijing, Chongqing, Fuzhou, Lanzhou, Guangzhou

2024-11-14

Active, closed

Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in PNH Patients.

NCT07212426PNH - Paroxysmal Nocturnal Hemoglobinuria

DrugLP-005

Longbio Pharma

Phase 2

Nanjing

2024-11-14

Not yet open

Irinotecan Liposomes +5-FU/LV Versus Capecitabine in Patients of Recurrence After Resection of Resectable BTC

NCT06699459Biliary Tract Carcinoma

DrugsIrinotecan liposome·Capecitabine

Sir Run Run Shaw Hospital

Phase 2

Fuzhou, Guangzhou, Shanghai, Hangzhou

2024-11-14

Not yet open

A Phase I Clinical Trial Evaluating the Safety, Tolerability and Pharmacokinetics of AAPB for Injection

NCT06679998Acute Ischemic Stroke (AIS)

Jiangsu Kanion Pharmaceutical Co., Ltd

Phase 1

Beijing

2024-11-14

Recruiting

A Clinical Research About CD70-targeted CAR-NKT Cells Therapy in Subjects with Advanced Malignant Solid Tumors

NCT06728189Advanced Malignant Solid Tumors

Peking University Cancer Hospital & Institute

Phase 1

Beijing

2024-11-14

Recruiting

Trifluridine/tipiracil (TAS-102), Bevacizumab, and Camrelizumab As Third-line or Later-line Therapy of Gastric Cancer

NCT06711471Gastric Cancer Adenocarcinoma Metastatic

DrugCamrelizumab

LIN YANG

Phase 2

Beijing

2024-11-14

Recruiting

Impact of Pet Cats on Nasal and Gut Microbiota in Patients With Cat Allergen Allergy

NCT07110311Allergic Rhinitis

The First Affiliated Hospital with Nanjing Medical University

Observational

100

Nanjing

2024-11-14

Recruiting

Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma

NCT06714383Osteosarcoma

DrugsLobaplatin·Pirarubicin·Trilaciclib

Peking University People's Hospital

Phase 2

Beijing

2024-11-13

Recruiting

Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Biliary Tract Cancer Recurrence Surveillance

NCT06653127Biliary Tract Cancer

Tongji Hospital

Observational

Wuhan

2024-11-13

Recruiting

Propranolol Hydrochloride in Combination With Sintilimab and Platinum-based Chemotherapy for Treatment of Advanced Non-small Cell Lung Cancer

NCT05979818Non Small Cell Lung Cancer, Propranolol

DrugsPropranolol·Sintilimab

Second Xiangya Hospital of Central South University

Phase 1

Changsha

2024-11-13

Active, closed

Safety and Immunogenicity of Recombinant RSV Vaccine (CHO Cell) in Healthy Subjects Aged 18 Years and Above

NCT06642558Respiratory Syncytial Virus (RSV)

MAXVAX Biotechnology Limited Liability Company

Phase 1/2

522

Shangqiu

2024-11-13

Recruiting

A Study of SHR-3821 Injection in Subjects With Advanced Solid Tumors

NCT06618651Advanced Solid Tumors

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 1

162

Chengdu

2024-11-13

Recruiting

Evaluating the Safety and Effectiveness of 5G Cloud Follow-up for Cardiovascular Implantable Electronic Devices

NCT06652750Sick Sinus Syndrome, Atrioventricular Block, Second and Third Degree, Heart Failure

The Third People's Hospital of Chengdu

Not applicable

688

Guangzhou, Chengdu

2024-11-13

Recruiting

Orelabrutinib Combined With Zuberitamab in the Initial Treatment of MZL

NCT06985472Initial MZL, Untreated MZL, BTKi, CD20

Li Zhiming

Phase 2

Guangzhou

2024-11-13

By invitation

IMRT Combined With Lobaplatin-based CCRT in Nasopharyngeal Carcinoma

NCT06688175Nasopharyngeal Neoplasms, Elderly, Chemotherapy

DrugIMRT

The First Affiliated Hospital of Xiamen University

Phase 2

Xiamen

2024-11-13

Active, closed

PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer

NCT06616532SCLC

DrugsPumitamig·Topotecan·Paclitaxel

Biotheus Inc.

Phase 3

404

Binzhou, Changchun, Changsha, Chengdu, Chenzhou, Chongqing, Dalian, Foshan

2024-11-13

Recruiting

A Study of FC084CSA in Combination of Tislelizumab in Patients With Advanced Malignant Solid Tumors

NCT06499350Advanced Malignant Solid Tumors

DrugExpansion

FindCure Biosciences (ZhongShan) Co., Ltd.

Phase 1/2

Shanghai

2024-11-13

Active, closed

A Phase II Study of Zuberitamab Injection in Patients With Primary Membranous Nephropathy

NCT06642909Primary Membranous Nephropathy

DrugsCyclosporine·Lisaftoclax

BioRay Pharmaceutical Co., Ltd.

Phase 2

135

Shanghai

2024-11-13

By invitation

Multicenter Prospective Cohort Study of Hypertriglyceridemia Acute Pancreatitis

NCT06976099Acute Pancreatitis (AP), Hypertriglyceridemia Acute Pancreatitis

Peking Union Medical College Hospital

Observational

1,000

Beijing, Guangzhou, Zunyi, Harbin, Changsha, Nanjing, Yangzhou, Dalian

2024-11-13

Active, closed

A Real-world Study to Assess Safety of OZURDEX® (Dexamethasone Intravitreal Implant) in Adult Participants With Diabetic Macular Edema in China

NCT06548568Diabetic Macular Edema

AbbVie

Observational

110

Beijing, Xiamen, Guangzhou, Zhengzhou, Wuhan, Dalian, Xi'an, Qingdao

2024-11-13

Recruiting

A Phase 2 Clinical Study of ABSK061 and ABSK043

NCT06632262HER2-Gastric/Gastroesophageal Junction Cancer, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Solid Tumors

DrugsABSK061·ABSK043·Folfox

Abbisko Therapeutics Co, Ltd

Phase 2

202

Guiyang, Shijiazhuang, Harbin, Zhengzhou, Changsha, Nanchang, Shenyang, Jinan

2024-11-13

Recruiting

A Clinical Follow-up Study on the Efficacy of Thumbtack Needle for Postoperative Sleep and Recovery Treatment

NCT06757023Postoperative Complications, Postoperative Pain, Acupuncture

The First Affiliated Hospital of Xiamen University

Observational

110

Xiamen

2024-11-13

Active, closed

Efficacy of Home-based Treatment for Breast Cancer-related Lymphedema

NCT06783543Lymphedema Arm

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

Hangzhou

2024-11-13

Recruiting

Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study

NCT06831435Depression, Bipolar Affective Disorder, Schizophenia Disorder, Psychiatric &Amp;or Mood Disorder

Peking University

Not applicable

325

Beijing

2024-11-13

Recruiting

Sintilimab Plus Rituximab Followed by R-CHOP Regimen in Untreated PMBL

NCT06742502Primary Mediastinal Diffuse Large B-cell Lymphoma

Sun Yat-sen University

Phase 2

Fuzhou, Guangzhou

2024-11-12

Recruiting

Toripalimab Combined With Gemcitabine and Cisplatin (GemCis) as Preoperative Neoadjuvant Therapy for Resectable Intrahepatic Cholangiocarcinoma

NCT06721286Intrahepatic Cholangiocarcinoma (Icc)

DrugsGemcitabine·Cisplatin

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-11-12

Recruiting

Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor

NCT07433283Tumor, Solid, Lung Cancer, Pancreas Cancer, Thyroid Cancer

Sichuan Enray Pharmaceutical Sciences Company

Phase 1/2

Beijing, Hunan, Chongqing, Fuzhou, Haikou, Heilongjiang, Shanghai, Chengdu

2024-11-12

Recruiting

Efficacy and Safety of Ursodeoxycholic Acid in Reversing Gastric Intestinal Metaplasia

NCT06610760Gastric Intestinal Metaplasia

DrugUrsodeoxycholic Acid

Yongquan Shi

Phase 4

196

Pingdingshan, Ankang, Hanzhong, Shangluo, Xi'an

2024-11-12

Recruiting

Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab

NCT06540326Colorectal Cancer Metastatic

DrugsIrinotecan liposome·Fluorouracil·Cetuximab·Adrucil

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

100

Hangzhou

2024-11-12

Recruiting

Prophylactic Intervention for Relapse Prevention Post-Allogeneic Transplantation in Very High-Risk MDS Patients Based on IPSS-M Stratification

NCT06612944Myelodysplastic Syndromes, Adult

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Phase 2

Shanghai

2024-11-12

Recruiting

An Exploratory, Multi-cohort Phase II Study of Combination Therapy With AK104 and AK112 for Recurrent Ovarian Cancer

NCT06560112Recurrent Ovarian Cancer

DrugsCadonilimab·Ivonescimab

Akeso

Phase 2

172

Shanghai

2024-11-12

Recruiting

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

NCT06632457Metabolic Dysfunction Associated Steatohepatitis

Boehringer Ingelheim

Phase 3

1,590

Beijing, Changchun, Changsha, Changzhou Shi, Chengdu, Chongqing, Foshan, Fuzhou

2024-11-12

Not yet open

EOCRCPred: an AI Model to Predict Survival in EOCRC Patients After Surgery

NCT06690606Colorectal Cancer

Shanghai University of Traditional Chinese Medicine

Observational

250

Shanghai

2024-11-12

Active, closed

A Clinical Study of Recombinant Human Coagulation Factor VIII for Injection in Patients With Severe Hemophilia A

NCT06297655Hemophilia A

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 3

Fuyang, Hefei, Chongqing, Lanzhou, Guangzhou, Nanning, Zhengzhou, Changsha

2024-11-12

Recruiting

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Patients

NCT06621173Metastatic Colorectal Cancer (mCRC)

DrugHNF4α srRNA

Shanghai Changzheng Hospital

Early Phase 1

Shanghai

2024-11-12

Active, closed

Toripalimab Combined With Capecitabine as Postoperative Adjuvant Therapy for Patients With Resectable Advanced Extrahepatic Biliary Tract Cancer

NCT06717464Gallbladder Cancer, Hilar Cholangiocarcinoma, Distal Cholangiocarcinoma

DrugsToripalimab·Capecitabine

Tianjin Medical University Cancer Institute and Hospital

Phase 2

110

Tianjin

2024-11-12

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site. Derived from ClinicalTrials.gov. Retrieved 7 November 2026. https://priyalifescience.com/clinical-trials-china?page=23

Query this register directly

GET /api/trials?country=cn&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,187 studies in total at the last sync on 07 Nov 2026, 03:17 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in China?

11,790 of the 19,187 studies in this register are recruiting new participants as of the 07 Nov 2026, 03:17 UTC sync. A further 3,998 have not yet opened recruitment, 2,715 are active but closed to new participants, and 684 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (423) Advanced Solid Tumors (187) Colorectal Cancer (179) Gastric Cancer (175) Hepatocellular Carcinoma (154) Advanced Solid Tumor (153) Non-Small Cell Lung Cancer (145) Solid Tumor (142) Acute Ischemic Stroke (140) Lung Cancer (135) Non-small Cell Lung Cancer (132) Pancreatic Cancer (131) Multiple Myeloma (128) Coronary Artery Disease (122) Prostate Cancer (110)

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Browse trials by site location

Beijing (5576) Shanghai (3879) Guangzhou (3345) Hangzhou (1819) Wuhan (1343) Chengdu (1307) Nanjing (1211) Changsha (1154) Chongqing (1078) Fuzhou (1040) Tianjin (934) Zhengzhou (931) Hefei (896) Jinan (783) Changchun (639)

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.