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Compound · clinical trials

Liposomal bupivacaine

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 15 trials in our China and USA registers that name Liposomal bupivacaine as an intervention. Synced 24 Sep 2026
15Trials tracked
10Recruiting now
10Lead sponsors
2Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Liposomal bupivacaine is named as a drug or biological intervention in 15 clinical trials in our China and USA trial registers, 10 of which are recruiting. Lead sponsors include Beijing Tiantan Hospital (6), TLC Biopharmaceuticals, Inc. (1) and The Second Affiliated Hospital of Chongqing Medical University (1). Registered phases: Not applicable, Phase 4 and Phase 3. Conditions studied include Liposomal Bupivacaine; Postoperative Pain; Pain Management.

01

Clinical trials of Liposomal bupivacaine

15 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT06569953 Efficacy and Safety of Liposomal Bupivacaine Injection for Paravertebral Nerve Block in the Treatment of Acute and Chronic Pain After Thoracoscopic Pneumonectomy: A Multicenter, Randomized, Double-blind, Controlled Clinical Trial (ClinicalTrials.gov ↗)
Acute Pain, Chronic Pain, Postoperative Pain
Phase 4 Recruiting The Second Affiliated Hospital of Chongqing Medical University China
NCT06704698 Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery (ClinicalTrials.gov ↗)
Pain Syndrome, Dizziness, Vomiting
Not applicable Recruiting Zhejiang Cancer Hospital China
NCT07432711 The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery
Video-assisted Thoracoscopic Surgery (VATS), Pain Management, Liposomal Bupivacaine
Not applicable Recruiting Beijing Tiantan Hospital China
NCT07441902 The Efficacy and Safety of Liposomal Bupivacaine for Rhomboid Intercostal Nerve Block in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery (ClinicalTrials.gov ↗)
Video-assisted Thoracoscopic Surgery (VATS), Pain Management, Liposomal Bupivacaine
Not applicable Recruiting Beijing Tiantan Hospital China
NCT07442539 The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery (ClinicalTrials.gov ↗)
Hemorrhoid Surgery, Liposome Bupivacaine, Pain Management
Not applicable Recruiting Beijing Tiantan Hospital China
NCT07458256 The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Laparoscopic Surgery (ClinicalTrials.gov ↗)
Laparoscopic Surgery, Liposomal Bupivacaine, Local Infiltration
Not applicable Recruiting Beijing Tiantan Hospital China
NCT07458282 The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery (ClinicalTrials.gov ↗)
Laparoscopic Surgery, Liposomal Bupivacaine, Transversus Abdominis Plane Block
Not applicable Recruiting Beijing Tiantan Hospital China
NCT07458295 The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology (ClinicalTrials.gov ↗)
Laparoscopic Surgery, Gynecologic Oncology Patient, Liposomal Bupivacaine
Not applicable Recruiting Beijing Tiantan Hospital China
NCT07509866 Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty (ClinicalTrials.gov ↗)
Total Knee Anthroplasty, Nerve Block, Ropivacaine
Not applicable Recruiting Huazhong University of Science and Technology China
NCT07651722 Effect of Liposomal Bupivacaine TAPB Combined With Oxycodone PCIA on Postoperative Gastrointestinal Recovery in Patients Undergoing Major Abdominal Surgery (ClinicalTrials.gov ↗)
Postoperative Pain, Postoperative Ileus
Not applicable Recruiting Tianjin First Central Hospital China
NCT07606911 Effect of Liposomal Bupivacaine on Rebound Pain After Peripheral Nerve Block in Orthopedic Surgery. (ClinicalTrials.gov ↗)
Acute Pain, Orthopaedic Surgery
Phase 4 Not yet open Shanghai Jiao Tong University Affiliated Sixth People's Hospital China
NCT07643792 Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Surgery (ClinicalTrials.gov ↗)
Fascia Iliaca Block, Liposomal Bupivacaine, Postoperative Pain
Phase 4 Not yet open Peking University First Hospital China
NCT07667439 The Effect of Liposomal Bupivacaine Erector Spinae Plane Block (ClinicalTrials.gov ↗)
Liposome Bupivacaine, Erector Spinae Plane Block, Postoperative Analgesia
Not applicable Not yet open Second Affiliated Hospital, Zhejiang University, School of Medicine China
NCT07587203 Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia (ClinicalTrials.gov ↗)
Proximal Humerus Surgery, Rotator Cuff Surgery, Shoulder Arthroplasty
Not applicable By invitation Nanjing First Hospital, Nanjing Medical University China
NCT07222748 A Study of TLC590 for Postsurgical Pain Following Bunionectomy (ClinicalTrials.gov ↗)
Postoperative Pain
Phase 3 Active, closed TLC Biopharmaceuticals, Inc. USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

32 conditions
Condition (as registered)Trials
Liposomal Bupivacaine7
Postoperative Pain4
Pain Management3
Laparoscopic Surgery3
Video-assisted Thoracoscopic Surgery (VATS)2
Acute Pain2
Liposome Bupivacaine2
Local Infiltration2
Transversus Abdominis Plane Block2
Local Injection1
Chronic Pain1
Total Knee Anthroplasty1
Nerve Block1
Ropivacaine1
Orthopaedic Surgery1
Postoperative Ileus1
Pain Syndrome1
Dizziness1
Vomiting1
Itching1
Hemorrhoid Surgery1
Proximal Humerus Surgery1
Rotator Cuff Surgery1
Shoulder Arthroplasty1
Shoulder Arthroscopy1
Erector Spinae Plane Block1
Postoperative Analgesia1
Randomized Controlled Trial1
Rhomboid Intercostal Block1
Gynecologic Oncology Patient1
Fascia Iliaca Block1
Hip Surgery1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Beijing Tiantan Hospital6
TLC Biopharmaceuticals, Inc.1
The Second Affiliated Hospital of Chongqing Medical University1
Huazhong University of Science and Technology1
Shanghai Jiao Tong University Affiliated Sixth People's Hospital1
Tianjin First Central Hospital1
Zhejiang Cancer Hospital1
Nanjing First Hospital, Nanjing Medical University1
Second Affiliated Hospital, Zhejiang University, School of Medicine1
Peking University First Hospital1
04

Trials by country register

RegisterLiposomal bupivacaine trials
Clinical trials in China14
Clinical trials in USA1

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Liposomal bupivacaine works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Liposomal bupivacaine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.