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Priya Life Science Compound trial record
Compound · clinical trials

Homoharringtonine clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 17 trials in our China register that name Homoharringtonine as an intervention. Synced 8 Nov 2026
17Current trials
10Recruiting now
8Lead sponsors
1Country register
At a glance

Homoharringtonine is named as an intervention in 17 current clinical trials in our China register. 10 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Institute of Hematology & Blood Diseases Hospital, China (5). The most-studied condition is Acute Myeloid Leukemia (AML).

Where Homoharringtonine is approved

All regulators →
USUnited States (FDA)
No FDA approval of a single-substance product in Drugs@FDA
First original NDA/BLA approval
EUEuropean Union (EMA)
No centralised EU authorisation (it may be authorised nationally)
First centralised authorisation
CACanada (Health Canada)
No new-drug Notice of Compliance since 1994
First new-drug NOC

From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.

How Homoharringtonine works

All drug targets →
Diseases it has been tested for in clinical trials, by furthest phase
  • T-cell acute lymphoblastic leukemiaPhase 3
  • T-cell adult acute lymphocytic leukemiaPhase 3
  • Acute lymphoblastic leukemiaPhase 3
  • Acute myeloid leukemiaPhase 3
  • Chronic myeloid leukemiaPhase 3
  • Myelodysplastic syndromePhase 3
  • LeukemiaPhase 2
  • LymphomaPhase 2
  • Mixed phenotype acute leukemiaPhase 2
  • Myeloid leukemiaPhase 2
16 diseases in all

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL46286, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 7454, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Homoharringtonine

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Reference identifiers for Homoharringtonine

ATC code
L01XX40
ChEMBL
CHEMBL46286
DrugBank
DB04865
PubChem CID
285033
CAS number
26833-87-4
FDA UNII
6FG8041S5B
Wikidata
Q7089373
Wikipedia
Omacetaxine mepesuccinate

Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.

Trials by status

  • Recruiting1059%
  • Not yet open318%
  • Active, closed16%
  • By invitation318%

Trials by phase

  • Phase 2741%
  • Phase 2/3424%
  • Not applicable318%
  • Phase 3212%
  • Phase 1/216%
01

Clinical trials of Homoharringtonine

17 trials
StudyPhaseStatusLead sponsorRegisters
Comparing the Efficacy of VHAG and Traditional Chemotherapy Regimens in Newly Diagnosed ETP-ALL
NCT06361329 · ClinicalTrials.gov ↗ · ETP-ALL
Phase 3 Recruiting First Affiliated Hospital of Zhejiang University China
Venetoclax Combined With Homoharringtonine and Cytarabine in Induction for AML
NCT05805098 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
Phase 2/3 Recruiting The First Affiliated Hospital of Soochow University China
Newly-diagnosed Pediatric T-cell ALL Protocol
NCT06855810 · ClinicalTrials.gov ↗ · Acute Lymphoblastic Leukemia, Childhood Leukemia, Acute Lymphoblastic, T Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Phase 2/3 Recruiting Institute of Hematology & Blood Diseases Hospital, China China
Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML
NCT06221683 · ClinicalTrials.gov ↗ · AML, Childhood, Acute Myeloid Leukemia
Phase 2 Recruiting Children's Hospital of Soochow University China
VHAG in Treating R/R T-ALL/LBL
NCT06742463 · ClinicalTrials.gov ↗ · Acute T Lymphpblastic Leukemia/Lymphoma
Phase 2 Recruiting First Affiliated Hospital of Zhejiang University China
Clinical Study on Neoadjuvant Therapy of Homoharringtonine Combined With Androgen Deprivation for Prostate Cancer
NCT06834321 · ClinicalTrials.gov ↗ · Prostate CA
Phase 2 Recruiting baotai Liang China
Homoharringtonine Plus Androgen Deprivation Therapy in the Neoadjuvant Treatment of Prostate Cancer: A Single-Arm Clinical Study
NCT07163910 · ClinicalTrials.gov ↗ · Prostate Cancer
Phase 2 Recruiting baotai Liang China
Multicenter, Platform-type Clinical Study of Refractory/Recurrent Acute Myeloid Leukemia
NCT06265545 · ClinicalTrials.gov ↗ · AML, Refractory, Relapsed
Not applicable Recruiting Institute of Hematology & Blood Diseases Hospital, China China
Intermediate-dose HAD Regimen for CEBPA Double-mutated AML
NCT06529250 · ClinicalTrials.gov ↗ · AML
Not applicable Recruiting Institute of Hematology & Blood Diseases Hospital, China China
MRD-positive AML Clinical Study
NCT07131059 · ClinicalTrials.gov ↗ · AML, Adult
Not applicable Recruiting Institute of Hematology & Blood Diseases Hospital, China China
VAH vs VA in Newly Diagnosed Elderly AML
NCT07469046 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia (AML), Elderly Patients (60-75 Years)
Phase 3 Not yet open Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine China
Efficacy and Safety of Lisafotoclax Plus Decitabine and Homoharringtonine in Venetoclax/Azacitidine Pretreated AML Patients
NCT07505160 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia (AML)
Phase 2 Not yet open Second Affiliated Hospital, Zhejiang University, School of Medicine China
Homoharringtonine, BCL-2 Inhibitor, Rituximab, and Prednisone in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
NCT07159906 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma
Phase 1/2 Not yet open First Affiliated Hospital of Zhejiang University China
Comparing the Efficacy of LDA, LHAA, and LA Regimens in Young Adults With Intermediate- and High-Risk Acute Myeloid Leukemia Eligible for Intensive Chemotherapy
NCT07651163 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia (AML), Lisaftoclax
Phase 2/3 By invitation First Affiliated Hospital of Zhejiang University China
Comparing the Efficacy of the LDA, LHAA, and DA Regimens in Young Adults With Low-Risk Acute Myeloid Leukemia Eligible for Intensive Chemotherapy
NCT07651176 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia, Lisaftoclax
Phase 2/3 By invitation First Affiliated Hospital of Zhejiang University China
Homoharringtonine, Lisaftoclax, and Azacitidine for AML After Venetoclax-Based Therapy Failure
NCT07813390 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia (AML)
Phase 2 By invitation Guangdong Second Provincial General Hospital China
HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML
NCT06744556 · ClinicalTrials.gov ↗ · AML
Phase 2 Active, closed Institute of Hematology & Blood Diseases Hospital, China China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Homoharringtonine

19 conditions
Acute Myeloid Leukemia (AML)4AML3Acute Myeloid Leukemia3Lisaftoclax2AML, Adult1Acute T Lymphpblastic Leukemia/Lymphoma1ETP-ALL1Diffuse Large B-Cell Lymphoma1Relapsed Non-Hodgkin Lymphoma1Refractory Non-Hodgkin Lymphoma1Elderly Patients (60-75 Years)1Prostate CA1
All 19 conditions
Condition (as registered)Trials
Acute Myeloid Leukemia (AML)4
AML3
Acute Myeloid Leukemia3
Lisaftoclax2
AML, Adult1
Acute T Lymphpblastic Leukemia/Lymphoma1
ETP-ALL1
Diffuse Large B-Cell Lymphoma1
Relapsed Non-Hodgkin Lymphoma1
Refractory Non-Hodgkin Lymphoma1
Elderly Patients (60-75 Years)1
Prostate CA1
Acute Lymphoblastic Leukemia1
Childhood Leukemia, Acute Lymphoblastic1
T Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma1
AML, Childhood1
Prostate Cancer1
Refractory1
Relapsed1
05

Related compounds

06

Questions about Homoharringtonine trials

How many clinical trials are testing Homoharringtonine?

17 current trials in our China register name Homoharringtonine as a drug or biological intervention, as of the registry sync on 8 November 2026. Completed and withdrawn studies are not counted.

Are Homoharringtonine trials recruiting patients?

Yes. 10 of the 17 trials are recruiting: 10 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Homoharringtonine clinical trials?

Institute of Hematology & Blood Diseases Hospital, China (5), First Affiliated Hospital of Zhejiang University (5), baotai Liang (2) and Guangdong Second Provincial General Hospital (1), among 8 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Homoharringtonine works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Homoharringtonine works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Homoharringtonine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 8 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.