Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact
Priya Life Science Compound trial record
Compound · clinical trials

Trilaciclib clinical trials

Also listed in trial records as Cosela, G1T28
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 14 trials in our China, USA and Spain registers that name Trilaciclib as an intervention. Synced 9 Nov 2026
14Current trials
9Recruiting now
11Lead sponsors
3Country registers
At a glance

Trilaciclib is named as an intervention in 14 current clinical trials in our China, USA and Spain registers. 9 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Sun Yat-sen University (3). The most-studied condition is Myelosuppression.

How Trilaciclib works

All drug targets →
  • Cyclin-dependent kinase 4 inhibitor Inhibitor
    Target: CDK4 cyclin dependent kinase 4
    ✓ In ChEMBL and the Guide to Pharmacology
  • Cyclin-dependent kinase 6 inhibitor Inhibitor
    Target: CDK6 cyclin dependent kinase 6
    ✓ In ChEMBL and the Guide to Pharmacology
Other medicines acting on CDK4
Other medicines acting on CDK6
Diseases it has been tested for in clinical trials, by furthest phase
  • Triple-negative breast carcinomaPhase 3
  • Urothelial carcinomaPhase 3
  • HER2 positive breast carcinomaPhase 2
  • Breast cancerPhase 2
  • Diffuse large B-cell lymphomaPhase 2
  • Esophageal squamous cell carcinomaPhase 2
  • Exocrine pancreatic carcinomaPhase 2
  • Leptomeningeal metastasisPhase 2
  • Non-small cell lung carcinomaPhase 2
  • OsteosarcomaPhase 2

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL3894860, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 9626, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Trilaciclib

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Reference identifiers for Trilaciclib

ChEMBL
CHEMBL3894860
DrugBank
DB15442
PubChem CID
68029831
CAS number
1374743-00-6
FDA UNII
U6072DO9XG
Wikidata
Q105592965
Wikipedia
Trilaciclib

Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.

Trials by status

  • Recruiting964%
  • Not yet open214%
  • Active, closed214%
  • By invitation17%

Trials by phase

  • Phase 21071%
  • Phase 3214%
  • Observational17%
  • Phase 417%
01

Clinical trials of Trilaciclib

14 trials
StudyPhaseStatusLead sponsorRegisters
Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer
NCT07473128 · Limited Stage Small Cell Lung Cancer
Phase 3 Recruiting Pharmacosmos A/S USA
Trilaciclib in Patients With Early-Stage HR-negative Breast Cancer Receiving Adjuvant Chemotherapy
NCT05978648 · ClinicalTrials.gov ↗ · Breast Neoplasms
Phase 2 Recruiting wang shusen China
A Study of Trilaciclib Combined With Chemotherapy in the Treatment of Diffuse Large B-Cell Lymphoma Patients
NCT06569485 · ClinicalTrials.gov ↗ · DLBCL
Phase 2 Recruiting Sun Yat-sen University China
Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin
NCT06698965 · ClinicalTrials.gov ↗ · Lung Cancer, Small Cell
Phase 2 Recruiting Shanghai Chest Hospital China
A Prospective, Randomized, Controlled Clinical Study on the Prevention of Chemotherapy Related Myelosuppression in Patients with Ewing's Sarcoma Using Trilaciclib
NCT06699472 · ClinicalTrials.gov ↗ · Ewing Sarcoma, Myelosuppression
Phase 2 Recruiting Fudan University China
Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma
NCT06714383 · ClinicalTrials.gov ↗ · Osteosarcoma
Phase 2 Recruiting Peking University People's Hospital China
Bone Marrow Protective Effect of Trilaciclib in Postoperative CCRT for LA-HNSCC
NCT06752798 · ClinicalTrials.gov ↗ · Head and Neck Cancer Squamous Cell Carcinoma
Phase 2 Recruiting Hunan Cancer Hospital China
Trilaciclib in Combination With Docetaxel for Second-Line and Beyond Treatment of Locally Advanced or Metastatic NSCLC
NCT06929936 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer, Myelosuppression
Phase 2 Recruiting The First Affiliated Hospital of Xiamen University China
Trilaciclib for the Prevention of Chemoradiotherapy-Induced Myelosuppression in Esophageal Squamous Cell Carcinoma
NCT06698692 · ClinicalTrials.gov ↗ · ESCC
Observational Recruiting The First Affiliated Hospital with Nanjing Medical University China
Myeloprotection With Trilaciclib in Pan-cancer Population
NCT06297811 · Non-Small Cell Lung Cancer, Breast Cancer, Endometrial Cancer
Phase 2 Not yet open Sun Yat-sen University China
Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer)
NCT07255612 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 2 Not yet open Sun Yat-sen University China
the Prevention of Bone Marrow Suppression Caused by Chemotherapy in Advanced NSCLC With Trilaciclib
NCT06370416 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2 By invitation Henan Cancer Hospital China
Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan
NCT05874401 · ClinicalTrials.gov ↗ · Extensive-stage Small-cell Lung Cancer
Phase 4 Active, closed Pharmacosmos A/S Spain
A Phase III, Randomized, Double-blind, Multi-center Trial Comparing Efficacy and Safety of Trilaciclib Versus Placebo in Participants With Limited-stage Small Cell Lung Cancer
NCT07881705 · ClinicalTrials.gov ↗ · Myelosuppression
Phase 3 Active, closed Jiangsu Simcere Pharmaceutical Co., Ltd China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Trilaciclib

15 conditions
All 15 conditions
Condition (as registered)Trials
Myelosuppression3
Breast Cancer2
Non-Small Cell Lung Cancer2
Limited Stage Small Cell Lung Cancer1
Osteosarcoma1
Lung Cancer, Small Cell1
Endometrial Cancer1
Cervical Cancer1
Breast Neoplasms1
Ewing Sarcoma1
ESCC1
Head and Neck Cancer Squamous Cell Carcinoma1
Non-small Cell Lung Cancer1
DLBCL1
Extensive-stage Small-cell Lung Cancer1
05

Related compounds

06

Questions about Trilaciclib trials

How many clinical trials are testing Trilaciclib?

14 current trials in our China, USA and Spain registers name Trilaciclib (also registered as G1T28) as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Trilaciclib trials recruiting patients?

Yes. 9 of the 14 trials are recruiting: 8 with sites in China and 1 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Trilaciclib clinical trials?

Sun Yat-sen University (3), Pharmacosmos A/S (2), Peking University People's Hospital (1) and Shanghai Chest Hospital (1), among 11 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Trilaciclib works or whether it is effective, and it is not medical advice.

Approvals, shortages and trials, every Friday

One email a week with new EMA and FDA approvals, EU and US medicine shortages, how many trials are recruiting in Ireland, and the week's Irish pharma news.

Free. Unsubscribe from any email with one click. See our privacy policy.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Trilaciclib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Trilaciclib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.