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Compound · clinical trials

Third-generation EGFR-TKI clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 3 trials in our China register that name Third-generation EGFR-TKI as an intervention. Synced 25 Sep 2026
3Current trials
1Recruiting now
2Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Third-generation EGFR-TKI is named as an intervention in 3 current clinical trials in our China register. 1 is recruiting patients now. The most common phase is Observational. The sponsor with the most trials is Hunan Province Tumor Hospital (2). The most-studied condition is Non-small Cell Lung Cancer.

Trials by status

  • Recruiting133%
  • Not yet open267%

Trials by phase

  • Observational267%
  • Phase 2133%
01

Clinical trials of Third-generation EGFR-TKI

3 trials
StudyPhaseStatusLead sponsorRegisters
Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced NSCLC
NCT04324164 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Observational Recruiting Hunan Province Tumor Hospital China
Third-generation EGFR-TKI Plus Anlotinib as Maintenance for NSCLC With Small Cell Transformation After EGFR-TKI Resistance
NCT06634667 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2 Not yet open Hunan Province Tumor Hospital China
A Non-interventional, Real-world Study on the Adjuvant Treatment of Chinese EGFR-positive Stage IA NSCLC Patients With High-risk Factors Using Third-generation EGFR-TKIs.
NCT07686185 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer, Adjuvant Therapy
Observational Not yet open First Affiliated Hospital of Guangxi Medical University China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Third-generation EGFR-TKI

3 conditions
Non-small Cell Lung Cancer2Non-Small Cell Lung Cancer1Adjuvant Therapy1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Hunan Province Tumor Hospital2
First Affiliated Hospital of Guangxi Medical University1
04

By country register

RegisterTrialsRecruiting
Clinical trials in China31

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Third-generation EGFR-TKI trials

How many clinical trials are testing Third-generation EGFR-TKI?

3 current trials in our China register name Third-generation EGFR-TKI as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Third-generation EGFR-TKI trials recruiting patients?

Yes. 1 of the 3 trials is recruiting: 1 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Third-generation EGFR-TKI clinical trials?

Hunan Province Tumor Hospital (2) and First Affiliated Hospital of Guangxi Medical University (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Third-generation EGFR-TKI works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Third-generation EGFR-TKI works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Third-generation EGFR-TKI (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.