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Compound · clinical trials

Ropivacaine clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 8 trials in our China and USA registers that name Ropivacaine as an intervention. Synced 25 Sep 2026
8Current trials
5Recruiting now
7Lead sponsors
2Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Ropivacaine is named as an intervention in 8 current clinical trials in our China and USA registers. 5 are recruiting patients now. The most common phase is Not applicable. The sponsor with the most trials is Huazhong University of Science and Technology (2). The most-studied condition is Postsurgical Pain Management.

Trials by status

  • Recruiting563%
  • Not yet open113%
  • Active, closed113%
  • By invitation113%

Trials by phase

  • Not applicable450%
  • Phase 4338%
  • Phase 2113%
01

Clinical trials of Ropivacaine

8 trials
StudyPhaseStatusLead sponsorRegisters
Effect of Dexmedetomidine Combined With FNB/ACB on Sleep Quality After Knee Surgery
NCT07767383 · ClinicalTrials.gov ↗ · Knee Arthroscopic Surgery
Phase 4 Recruiting Affiliated Hospital of Nantong University China
A Study on TLC590 for Managing Postsurgical Pain
NCT06574269 · ClinicalTrials.gov ↗ · Postsurgical Pain Management
Phase 2 Recruiting TLC Biopharmaceuticals, Inc. USA
Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
NCT06819748 · ClinicalTrials.gov ↗ · Cholecystectomy, Laparoscopic, Ambulatory Surgical Procedures, Multimodal Analgesia
Not applicable Recruiting Sichuan Provincial People's Hospital China
Pre-emptive Scalp Infiltration With Low-dose Flurbiprofen and Ropivacaine for Postoperative Analgesia After Craniotomy
NCT07209345 · ClinicalTrials.gov ↗ · Post-craniotomy, Pain
Not applicable Recruiting Beijing Tiantan Hospital China
QLESP Block Versus PENG+LFCN Block for Total Hip Arthroplasty
NCT07771829 · ClinicalTrials.gov ↗ · Pain Management, Arthroplasty Total Hip Replacement
Not applicable Recruiting Huazhong University of Science and Technology China
QLESP Block for Pain Control in Robotic Partial Nephrectomy
NCT07704970 · Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain, Nerve Block
Not applicable Not yet open Huazhong University of Science and Technology China
Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia
NCT06711679 · ClinicalTrials.gov ↗ · Pediatric ALL
Phase 4 By invitation Yilin Zhao China
Anesthetic Effect of Ropivacaine on Local Infiltration Anesthesia in Arteriovenous Fistula Surgery
NCT07259772 · ClinicalTrials.gov ↗ · End Stage Renal Disease (ESRD), Arteriovenous Fistula Patency, Chronic Kidney Disease 5D
Phase 4 Active, closed The First People's Hospital of Lianyungang China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Ropivacaine across our data

Ireland · EU · US

The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.

Licensed in Ireland (HPRA)

4 single-substance products containing Ropivacaine on the HPRA medicines list.

  • Naropin 7.5 mg/ml solution for injectionRowex Limited, · PA0711/358/001 · Marketed
  • Ropivacaine 2 mg/ml solution for injectionFresenius Kabi Deutschland GmbH · PA2059/021/001 · Not marketed
  • Ropivacaine 7.5 mg/ml solution for injectionFresenius Kabi Deutschland GmbH · PA2059/021/002 · Not marketed
  • Ropivacaine Readyfusor 10 mg/h solution for infusion in administration systemBioQ Pharma B.V. · PA2284/001/001
All 4 Irish products →

Supply shortages

  • Ropivacaine Hydrochloride InjectionUS (FDA) · Current · updated 17 Sep 2026
  • Ropivacainhydrochlorid Kabi 2 mg/ml InjektionslรถsungGermany (BfArM) · Production problem · 3 Aug 2026 to 16 Nov 2026
  • Ropivacain HCl B. Braun 2 mg/ml Injektions-/InfusionslรถsungGermany (BfArM) · Other reason · 31 Aug 2026 to 30 Oct 2026
  • Ropivacainhydrochlorid Kabi 10 mg/ml InjektionslรถsungGermany (BfArM) · Production problem · 17 Aug 2026 to 9 Nov 2026
03

Conditions studied with Ropivacaine

16 conditions
Postsurgical Pain Management1Renal Cell Carcinoma (Kidney Cancer)1Postoperative Pain1Nerve Block1Knee Arthroscopic Surgery1Post-craniotomy1Pain1Pain Management1Arthroplasty Total Hip Replacement1End Stage Renal Disease (ESRD)1Arteriovenous Fistula Patency1Chronic Kidney Disease 5D1
All 16 conditions
Condition (as registered)Trials
Postsurgical Pain Management1
Renal Cell Carcinoma (Kidney Cancer)1
Postoperative Pain1
Nerve Block1
Knee Arthroscopic Surgery1
Post-craniotomy1
Pain1
Pain Management1
Arthroplasty Total Hip Replacement1
End Stage Renal Disease (ESRD)1
Arteriovenous Fistula Patency1
Chronic Kidney Disease 5D1
Pediatric ALL1
Cholecystectomy, Laparoscopic1
Ambulatory Surgical Procedures1
Multimodal Analgesia1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
Huazhong University of Science and Technology2
TLC Biopharmaceuticals, Inc.1
Affiliated Hospital of Nantong University1
Beijing Tiantan Hospital1
The First People's Hospital of Lianyungang1
Yilin Zhao1
Sichuan Provincial People's Hospital1
05

By country register

RegisterTrialsRecruiting
Clinical trials in China74
Clinical trials in USA11

A trial with sites in more than one country appears in each of those registers.

06

Related compounds

07

Questions about Ropivacaine trials

How many clinical trials are testing Ropivacaine?

8 current trials in our China and USA registers name Ropivacaine as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Ropivacaine trials recruiting patients?

Yes. 5 of the 8 trials are recruiting: 4 with sites in China and 1 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Ropivacaine clinical trials?

Huazhong University of Science and Technology (2), TLC Biopharmaceuticals, Inc (1), Affiliated Hospital of Nantong University (1) and Beijing Tiantan Hospital (1), among 7 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Is Ropivacaine licensed in Ireland?

Yes. The HPRA medicines list includes 4 single-substance products containing Ropivacaine, for example Naropin 7.5 mg/ml solution for injection (Rowex Limited,). A licence does not mean a product is currently marketed or reimbursed; see each product's record.

Is there a Ropivacaine shortage?

The registers we track list 4 entries for Ropivacaine: US FDA: current; 3 German notices. Shortages are product- and country-specific; check with a pharmacist.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Ropivacaine works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Ropivacaine works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Ropivacaine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.