Clinical trial register · China

Clinical Trials in China

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

Download CSV

Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 19187 matching records held by the registry are in this view. Synced 07 Nov 2026, 03:17 UTC

19187

Studies in scope

all four open statuses

11790

Recruiting now

open to new participants

2028

Lead sponsors

across recruiting studies

Top sites

Beijing 5576 Shanghai 3879 Guangzhou 3345 Hangzhou 1819 Wuhan 1343

Trials in this register

Status

Study

Lead sponsor

Phase

Enrol

Chinese sites

Start

Recruiting

A Study of AK104 in Subjects With Unresectable Locally Advanced NSCLC

NCT06617416NSCLC (Non-small Cell Lung Cancer)

DrugsSugemalimab·Cadonilimab

Akeso

Phase 3

560

Jinan

2024-11-12

Recruiting

Family-Based Moyamoya Susceptibility and Early Detection

NCT07517354Moyamoya Disease

Beijing Tiantan Hospital

Observational

700

Beijing

2024-11-12

Recruiting

Improved Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation Protocol for the Treatment of Epstein Barr Virus T/NK Lymphoproliferative Disease (EBV-T/NK LPD) and Prevention of Post Transplant Graft-versus-host Disease

NCT07029958EBV-T/NK LPD

Beijing Children's Hospital

Phase 4

Beijing

2024-11-12

Recruiting

HER2-PET: Predicting T-DXd Efficacy and HER2 Heterogeneity

NCT07586215Breast Cancer Metastatic

Fudan University

Observational

100

Shanghai

2024-11-11

Active, closed

A Study to Describe the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine IN006 in Healthy Adult Aged 18 Years and Above

NCT06645665Respiratory Syncytial Virus Infections

Shenzhen Shenxin Biotechnology Co., Ltd

Phase 1

240

Shanghai, Kunming

2024-11-11

Active, closed

A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)

NCT06537414Chronic Hepatitis B Virus Infection, Hepatitis B

DrugBepirovirsen

GlaxoSmithKline

Phase 2

283

Beijing, Chengdu, Guangzhou, Shanghai

2024-11-11

Recruiting

IMM01+Azacitidine VS Placebo +Azacitidine in Patients With Newly Diagnosed Chronic Myelomonocytic Leukemia (CMML1-2)

NCT06647862Chronic Myelomonocytic Leukemia

DrugsTimdarpacept·Azacitidine

ImmuneOnco Biopharmaceuticals (Shanghai) Inc.

Phase 3

170

Hefei, Beijing, Chongqing, Lanzhou, Nanning, Guangzhou, Shenzhen, Zhujiang

2024-11-11

Recruiting

Predicting Tumor Origin Based on Deep Learning of Lymph Node Puncture Cytology

NCT06810349Lymph Nodes With Tumor Metastasis

West China Hospital

Observational

10,000

Chengdu

2024-11-11

Recruiting

A Study of Olverembatinib in SDH-deficient GIST.

NCT06640361GIST

DrugOlverembatinib

Ascentage Pharma Group Inc.

Phase 3

Guangzhou

2024-11-11

Active, closed

Study of CM313 (SC) Injection in Subjects With Primary Immune Thrombocytopenia (ITP)

NCT06594146Primary Immune Thrombocytopenia

DrugCM313

Keymed Biosciences Co.Ltd

Phase 2

Tianjin

2024-11-11

Recruiting

Clinical Study of CD19 Targeted Universal Chimeric Antigen Receptor T Lymphocytes (UCAR-T) for the Treatment of Refractory Juvenile Dermatomyositis (RJDM)

NCT06686524Dermatomyositis, Juvenile, Dermatomyositis

Chongqing Precision Biotech Co., Ltd

Phase 1

Hangzhou

2024-11-11

Recruiting

Study of GP681 Tablets Compared With Placebo in Patients With Influenza at High Risk of Influenza Complications

NCT06573008Influenza, Human

DrugsGP681·GP681 Simulant

Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Phase 3

328

Chizhou

2024-11-11

Recruiting

Electroacupuncture Regulation of Immune Cells in Herpes Zoster

NCT06643247Herpes Zoster, Electroacupuncture, Immune

First People's Hospital of Hangzhou

Not applicable

Hangzhou

2024-11-11

Recruiting

A Real World Study About PMN

NCT06893328Primary Membranous Nephropathy

Wei Chen

Observational

200

Guangzhou

2024-11-11

Recruiting

Application of DCE-MRI Based on 4D FreeBreathing in Predicting the Efficacy of Immune and Targeted Therapy in Lung Cancer

NCT06742021Lung Cancer

Yunnan Cancer Hospital

Not applicable

195

Kunming

2024-11-11

Active, closed

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

NCT06719141Developmental and Epileptic Encephalopathy

DrugBexicaserin

Longboard Pharmaceuticals

Phase 3

367

Beijing, Guangzhou, Shenzhen Shi, Wuhan, Shanghai Shi

2024-11-11

Recruiting

An Observational Study of Coronary Microvascular Disease of China

NCT06676137Coronary Microvascular Disease

Henan Institute of Cardiovascular Epidemiology

Observational

500

Zhengzhou

2024-11-11

Recruiting

Comparison of Electrolyte Beverages and Water as Solvents for Bowel Preparation

NCT06675227Bowel Preparation Before Colonoscopy

Third Military Medical University

Not applicable

2,766

Chongqing

2024-11-11

Recruiting

Development and Application of Precision Treatment Strategies for Common Mental Disorders

NCT06729541Depression - Major Depressive Disorder, Schizophrenia Disorders, Bipolar Disorder (BD)

Peking University

Not applicable

600

Beijing

2024-11-11

Active, closed

Efficacy and Safety of Tegoprazan and Minocycline Dual Therapy for Helicobacter Pylori Initial Treatment

NCT06523764Helicobacter Pylori Infection Chronic Gastrit

DrugsBismuth Potassium Citrate·Minocycline·Tegoprazan·Clarithromycin

Xijing Hospital of Digestive Diseases

Phase 4

208

Xi'an

2024-11-11

By invitation

GCB-002 in Treatment of Patients With Rett Syndrome

NCT06739434RETT Syndrome With Proven MECP2 Mutation

Genecombio Ltd.

Not applicable

Shanghai

2024-11-11

Active, closed

Effect of Perioperative Roxadustat in Elective Lumbar Interbody Fusion Surgery.

NCT06772272Perioperative Anemia

DrugRoxadustat

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 3

158

Hangzhou

2024-11-10

Recruiting

Evaluating the Short-term Efficacy of Two Oscillation Techniques in Hypersecretive Mechanically Ventilated Patients

NCT06675942Hypersecretive Mechanically Ventilated Patients

Capital Medical University

Not applicable

Beijing

2024-11-10

Recruiting

Glofitamab Bridging ASCT for Patients With Relapsed or Refractory DLBCL

NCT06682130Diffuse Large B-cell Lymphoma(DLBCL)

The First Affiliated Hospital of Soochow University

Phase 2

Suzhou

2024-11-10

Recruiting

Model-Driven Individualized Transcranial Direct Current Stimulation for the Treatment of Insomnia Disorders

NCT06671457Insomnia

Zhen Wang

Not applicable

Shanghai

2024-11-10

Not yet open

Placebo Response of Different Types of Sham Acupuncture for Knee Osteoarthritis

NCT06675981Knee Osteoarthritis

West China Hospital

Not applicable

150

Nanchang, Chengdu

2024-11-10

Recruiting

Lusutrombopag Combined With Recombinant Human Thrombopoietin for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Destined to Undergo Elective Invasive Surgery

NCT06673498Thrombocytopenia

DrugsLusutrombopag·Recombinant Human Thrombopoietin

Anhui Provincial Hospital

Phase 2

Fuyang, Hefei

2024-11-10

Recruiting

A Randomized Controlled Trial of a Web-based Platform for Cancer Pain Management

NCT06663956Cancer Pain

West China Hospital

Phase 3

100

Chengdu

2024-11-10

Recruiting

The Value of 68Ga-grazytracer PET in Monitoring Responses to Immunotherapy of Advanced Hepatobiliary Malignancy

NCT06597539Hepatobiliary Malignancy

Ruijin Hospital

Observational

Shanghai

2024-11-09

Recruiting

The Application of CAR-T Cell Therapy in Relapsed and Refractory Malignant Hematologic Tumors

NCT06911710Lymphoma, B-cell, Aggressive Non-Hodgkin (B-NHL), AML (Acute Myelogenous Leukemia), Myeloma Multiple, B-ALL

Tianjin Medical University General Hospital

Phase 1/2

Tianjin

2024-11-09

Recruiting

Study on the Molecular Mechanism of Berberine to Improve Type 2 Diabetes Mellitus Complicated With Depression

NCT06979440Diabetes-Related Complications

Affiliated Hospital of Nantong University

Observational

Nantong

2024-11-09

Recruiting

Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast Cancer

NCT06658080Breast Cancer Metastatic, Hydrothorax, Ascites, Organoids

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

Hangzhou

2024-11-09

Recruiting

Study on Hibernation-like Therapy Based on Mechanical Thrombectomy

NCT06663631Acute Ischemic Stroke

DrugRt-PA

Capital Medical University

Phase 1

Linyi

2024-11-09

By invitation

Camrelizumab and Chemotherapy With or Without Anlotinib as First-line Treatment for Advanced Gallbladder Cancer and Extrahepatic Cholangiocarcinoma

NCT06901622Gallbladder Cancer and Extrahepatic Cholangiocarcinoma

The First Affiliated Hospital of Zhengzhou University

Phase 2

Zhengzhou

2024-11-08

Recruiting

Safety and Efficacy of Combined B Cell Depleting theRapy And Daratumumab In Autoimmune Encephalitis

NCT06867991Anti-N-Methyl-D-Aspartate Receptor Encephalitis

DrugsOfatumumab·Daratumumab

The First People's Hospital of Changzhou

Phase 3

200

Zhengzhou, Changzhou

2024-11-08

Recruiting

Baricitinib in the Treatment of Intestinal Behçet's Syndrome

NCT06849908Behcet Syndrome, Intestinal Type

DrugsHumira·Baricitinib·Adalimumab

Peking Union Medical College Hospital

Phase 2

Beijing

2024-11-08

Recruiting

A Study of CM383 in Patients With Alzheimer's Disease Related Mild Cognitive Impairment and Mild Alzheimer's Disease

NCT06619613Alzheimer Disease

Keymed Biosciences Co.Ltd

Phase 1

Hefei

2024-11-08

Recruiting

A Study of RNK08954 in Subjects With Advanced Solid Tumors With KRAS ((Kirsten Rat Sarcoma) G12D Mutation

NCT06667544KRAS G12D Mutation

Ranok Therapeutics (Hangzhou) Co., Ltd.

Phase 1/2

152

Nanning, Zhengzhou, Wuhan, Hangzhou, Shanghai

2024-11-08

Recruiting

Safety Study of CC312 in Autoimmune Disease Patients

NCT06888960Systemic Lupus Erythematosus (SLE), Idiopathic Inflammatory Myopathy (IIM), Systemic Sclerosis (SSc), Rheumatoid Arthritis (RA)

DrugCC312

CytoCares Inc

Early Phase 1

Tianjin

2024-11-08

Recruiting

Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer

NCT06468280Gastric Cancer, GastroEsophageal Cancer

DrugsZolbetuximab·Trastuzumab

Shanghai Zhongshan Hospital

Phase 2

Shanghai

2024-11-08

Recruiting

Safety and Effectiveness of the Peripheral Balloon-Expandable Covered Stent System for Iliac Artery Stenosis/Occlusion. (SELECT)

NCT06605209Peripheral Artery Disease (PAD)

Zhejiang Zylox Medical Device Co., Ltd.

Not applicable

130

Beijing

2024-11-08

Active, closed

A Study Assessing Adverse Events and Disease Activity of Intravenously (IV) Infused Telisotuzumab Adizutecan in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

NCT06614192Metastatic Colorectal Cancer

DrugTelisotuzumab Adizutecan

AbbVie

Phase 2

2024-11-08

Active, closed

A Study of the RNA Tumor Vaccine Targeting MICA/B in Patients With Advanced Solid Tumors

NCT06610227Advanced Solid Tumors

NING LI

Early Phase 1

Beijing

2024-11-08

Active, closed

A Study of SI-B001+SI-B003 Combined With Platinum-based Chemotherapy as First-line Treatment in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT06668961Head and Neck Squamous Cell Carcinoma

DrugsSI-B001·SI-B003

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 2

Shanghai

2024-11-07

Recruiting

Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT)

NCT06548971Acute Ischemic Stroke, Cerebral Infarction

DrugAspirin

Capital Medical University

Phase 3

1,184

Bengbu, Bozhou, Huaibei, Suzhou, Beijing, Haidian, Pinggu, Tongzhou

2024-11-07

Recruiting

Current Status of Islet Alpha Cell Function in Patients with Type 2 Diabetes

NCT06825182Type 2 Diabetes Mellitus

Nanjing First Hospital, Nanjing Medical University

Phase 3

1,000

Nanjing

2024-11-07

Active, closed

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

NCT06676319Asthma

DrugsBudesonide/Formoterol·Lunsekimig

Sanofi

Phase 2

556

Beijing, Changchun, Chengde, Chengdu, Foshan, Guangzhou, Guiyang, Hangzhou

2024-11-07

Recruiting

Prospective Observational Study on Comprehensive Effects of PEEK Cranioplasty and Titanium Cranioplasty After DC（RECEPT-DC）

NCT05416684Skull Defect

RenJi Hospital

Observational

358

Shanghai

2024-11-07

Recruiting

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α srRNA in Treating Advanced ICC Patients

NCT06583993Intrahepatic Cholangiocarcinoma

DrugHNF4α srRNA

Shanghai Changzheng Hospital

Early Phase 1

Shanghai

2024-11-07

Recruiting

Neoadjuvant Befotertinib Combined Bevacizumab or Platinum-based Double Chemotherapy for Resectable Locally-advanced EGFR Mutation-positive Non-Small Cell Lung Cancer

NCT06755684EGFR, Non-Small Cell Lung Cancer, Locally Advanced Non-Small Cell Lung Cancer, Pemetrexed

Peng Zhang

Phase 2

Shanghai

2024-11-07

Active, closed

Precise Design of Cell Therapy for Relapsed and Refractory Hematological Tumors

NCT06849921Precise Design of Cell Therapy for Relapsed and Refractory Hematological Tumors, Hematologic Disease

Ruijin Hospital

Not applicable

200

Shanghai

2024-11-07

Not yet open

The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM).

NCT06606509Type1 Diabetes Mellitus

Nanjing First Hospital, Nanjing Medical University

Observational

1,000

Anqing, Bengbu, Hefei, Wuhu, Beijing, Chongqing, Fuzhou, Quanzhou

2024-11-07

Recruiting

89Zr-TLX250 for PET/CT Imaging of ccRCC - ZIRCON-CP Study

NCT06750419Clear Cell Renal Cell Carcinoma

Telix Pharmaceuticals (Innovations) Pty Limited

Phase 3

Beijing, Hangzhou, Hubei, Shanghai, Suzhou, Tianjin, Wuxi, Zhejiang

2024-11-06

Recruiting

Evaluation of Long-term Isokinetic Training of Knee Joint

NCT06674473Knee Injuries and Disorders

Peking University Third Hospital

Not applicable

Beijing

2024-11-06

Recruiting

Seniors Integrated Longitudinal cardioVascular Evaluation of Coronary Heart Disease: a Multicenter, Prospective Registry in China (SILVER-China)

NCT06880575Coronary Arterial Disease (CAD), ELDERLY PEOPLE

Beijing Hospital

Observational

10,139

Beijing

2024-11-06

Recruiting

Nab-P+Cb+PD1 Inhibitors as Neoadjuvant Therapy for Early TNBC

NCT06817525Triple-negative Breast Cancer

Henan Cancer Hospital

Phase 2

Zhengzhou

2024-11-06

Active, closed

An Open-label, Multidose Dose-escalation Study to Understand the Safety of CRISPR Gene-editing Therapy and Its Long-Lasting Effects in DMD Patients (MUSCLE)

NCT06594094Duchenne Muscular Dystrophin (DMD)

HuidaGene Therapeutics Co., Ltd.

Early Phase 1

Shanghai

2024-11-06

Recruiting

RLC Followed by CR-CHOP in Elderly Patients with Newly-diagnosed DEL

NCT06674096Double-expressor Lymphoma

Zhejiang Cancer Hospital

Phase 2

Hangzhou

2024-11-06

Recruiting

A Clinical Study to Evaluate the Efficacy and Safety of TQB3702 Tablets Combined With Immunochemotherapy for the Treatment of B-cell Lymphoma

NCT06566586B-cell Lymphoma

DrugTQB3702

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 2

Beijing, Lanzhou, Guangzhou, Guigang, Nanning, Harbin, Anyang, Puyang

2024-11-06

Active, closed

Using a Novel Balloon-shaped Large-Focal Pulsed Field Ablation Catheter in Persistent Atrial Fibrillation

NCT07294742Persistent Atrial Fibrillation

The Third People's Hospital of Chengdu

Not applicable

Chengdu

2024-11-06

Recruiting

Non-Helium Magnetoencephalography in Pediatric Refractory Epilepsy

NCT07064421Refractory Epilepsy in Children

Guangzhou Women and Children's Medical Center

Observational

100

Guangzhou

2024-11-05

Recruiting

Non-Helium Magnetoencephalography in Autism Spectrum Disorder

NCT07064967Autism Spectrum Disorder (ASD)

Guangzhou Women and Children's Medical Center

Observational

Guangzhou

2024-11-05

Recruiting

A Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Initial Efficacy of HRS-4508 Monotherapy in Patients With Advanced or Metastatic Solid Tumors

NCT06598735Advanced Solid Tumors

DrugHRS-4508

Jiangsu HengRui Medicine Co., Ltd.

Phase 1

290

Beijing

2024-11-05

Recruiting

Non-Helium Magnetoencephalography in Pediatric Brain Tumors

NCT06943742Pediatric Brain Tumor

Guangzhou Women and Children's Medical Center

Observational

100

Guangzhou

2024-11-05

Recruiting

SBRT Combined With Nimotuzumab and Tislelizumab for Oligoprogressive Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of Immunotherapy

NCT06676722Nasopharyngeal Cancinoma (NPC), SBRT, Immunotherapy

DrugSBRT

The First Affiliated Hospital of Xiamen University

Phase 2

Xiamen

2024-11-05

Not yet open

Minimally Invasive Atlantoaxial Lateral Mass Joint Fusion (MIS-PALF) As a Surgical Treatment of Atlantoaxial Dislocation

NCT06678711Atlantoaxial Dislocation

Peking University Third Hospital

Not applicable

Beijing

2024-11-04

Recruiting

Comparison of Endoscopy and Esophagram for the Routine Evaluation of Anastomosis After McKeown Esophagectomy

NCT07043491Esophageal Cancer, Surgery-Complications

Sun Yat-sen University

Observational

Guangzhou

2024-11-04

Active, closed

A Study of the Efficacy and Safety of SHR-1314 for Adult Active Psoriatic Arthritis

NCT06640257Psoriatic Arthritis

DrugSHR-1314

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 3

208

Shanghai

2024-11-04

Recruiting

A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma

NCT06639347Advanced Urothelial Carcinoma

DrugsSHR-8068·SHR-A2102·Adebrelimab

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 1/2

Guangzhou

2024-11-04

Recruiting

Safety, Tolerability, and Preliminary Efficacy of KD01 Via Intravesical Instillation in Bladder Cancer (BC)

NCT07359235Bladder Cancer (BC)

DrugKD01

Tongji Hospital

Phase 1

Wuhan

2024-11-04

Recruiting

Fufang Congrong Yizhi Capsules (FCYC) of Cognitive Impairment After Intracerebral Hemorrhage

NCT06673602Cognitive Impairment, Intracerebral Hemorrhage

Qinhuangdao Hospital of Traditional Chinese Medicine

Phase 4

200

Beijing, Qinhuangdao, Kaifeng, Jinan, Weifang, Kunming

2024-11-04

Recruiting

A Phase I Study of CFT8919 in Patients With Advanced NSCLC

NCT06641609Non-Small Cell Lung Cancer With EGFR Mutation

Betta Pharmaceuticals Co., Ltd.

Phase 1

166

Hangzhou

2024-11-04

Recruiting

Clinical Specialty Queue For Gestational Trophoblastic Neoplasia

NCT06681259Gestational Trophoblastic Neoplasia

Women's Hospital School Of Medicine Zhejiang University

Observational

1,000

Zhengjiang

2024-11-04

Recruiting

Evaluation of Irinotecan Liposome (II) Combined With 5-FU, LV, and Bevacizumab for mCRC

NCT06643793Colorectal Neoplasms Malignant

DrugsIrinotecan liposome·Capecitabine·Bevacizumab

Affiliated Hospital of Nantong University

Phase 2

Nanjing

2024-11-04

Recruiting

All Trans Retinoic Acid Combined with Toripalimab+Chemotherapy for Locally Advanced Inoperable or Metastatic Triple Negative Breast Cancer：a Multi-center, Multi-cohort Phase II Trial

NCT06636981Triple Negative Breast Cancer (TNBC)

DrugToripalimab

Fudan University

Phase 2

129

Shanghai

2024-11-04

Recruiting

CD19 & CD22 Bispecific CAR T Cells in the Treatment of Relapsed/Refractory B Cell Hematologic Tumors

NCT06735495B-Cell Lymphoblastic Leukemia/Lymphoma

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 1/2

Wuhan

2024-11-04

Recruiting

Evaluating Modulation Effects of Temporal Interference Using SEEG

NCT06663969Deep Brain Stimulation, Drug Resistant Epilepsy

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-04

Recruiting

Clinical Trial of WBC100 Capsule in Relapsed/Refractory Acute Myeloid Leukemia

NCT07014449AML (Acute Myelogenous Leukemia, Relapsed Acute Myelogenous Leukemia, Refractory Acute Myeloid Leukemia, Hematologic Malignancy

Hangzhou Weben Pharma Co., Ltd

Phase 1

Hangzhou

2024-11-03

Active, closed

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

NCT06596694Gastrointestinal Cancer

DrugPatritumab deruxtecan

Merck Sharp & Dohme LLC

Phase 1/2

180

Hefei, Fuzhou, Xiamen, Guangzhou, Nanning, Zhengzhou, Shanghai, Taiyuan

2024-11-03

By invitation

Local Hyperthermia for the Treatment of Cervical Persistent High-risk Infection

NCT07059819Cervical Intraepithelial Neoplasia (CIN), Human Papillovirus

First Hospital of China Medical University

Not applicable

400

Shenyang

2024-11-02

Not yet open

A Multicenter, Single-arm, Open-label Study Evaluating the Safety and Efficacy of AK112 Combined With Chemotherapy as First-line Treatment for Non-squamous NSCLC Patients With BRAIN Metastases and Negative Driver Genes (IVO BRAIN)

NCT06684873NSCLC, Brain Metastasases

DrugIvonescimab

Sun Yat-sen University

Phase 2

Guangzhou

2024-11-02

Recruiting

68Ga-JH12 PET/CT: Dosimetry and Biodistribution Study

NCT06688188Malignant Neoplasm

First Affiliated Hospital of Fujian Medical University

Early Phase 1

Fuzhou

2024-11-01

Recruiting

Longitudinal Cohort of Thrombosis and Hemostasis Diseases

NCT06727669Immune Thrombocytopenia, Thrombotic Thrombocytopenic Purpura, Hemophilia A, Acquired, Disseminated Intravascular Coagulation

Peking University People's Hospital

Observational

3,000

Beijing, Zhengzhou, Chongqing

2024-11-01

By invitation

Evaluation of Endoscopic Treatment Effect Based on HVPG

NCT06863519Esophageal and Gastric Varices

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

Hangzhou

2024-11-01

Recruiting

Effect of WBT for CI With Depression

NCT06968013Chronic Insomnia, Depression Disorders

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

Recruiting

Study of Dalpiciclib Isethionate Plus Pyrotinib Maleate in the Treatment of Advanced Esophageal Squamous Cell Carcinoma

NCT06684600Esophageal Squamous Cell Carcinoma

DrugsDalpiciclib·Pyrotinib

Peking University

Phase 2

Beijing

2024-11-01

By invitation

Minimal Vitrectomy and ILM Flap with Sodium Hyaluronate Gel for MH

NCT06685328Macular Hole, Macular Hole Surgery, Idiopathic Macular Hole, Macular Hole of Left Eye (Disorder)

Jie Zhong

Not applicable

Chengdu

2024-11-01

Recruiting

Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations.

NCT06563999Lung Cancer Stage III, Mutation

DrugsPralsetinib·Glecirasib·Ensartinib·Larotrectinib

Sun Yat-sen University

Phase 2

120

Guangzhou

2024-11-01

Recruiting

Effects of Tai Chi on Chronic Insomnia Disorder Combined With Hyperarousal/Anxiety

NCT06967974Chronic Insomnia

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

Recruiting

Pomalidomide, Rituximab and Orelabrutinib Combined With Polatuzumab Vedotin in the Treatment of Newly Diagnosed Elderly Patients With DLBCL

NCT07072208Diffuse Large B-Cell Lymphoma

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-11-01

Recruiting

Ba Duan Jin for CI With Hyperarousal/Anxiety

NCT06969079Mind-Body Therapies, Insomnia Chronic

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

Active, closed

the Effect of Environmental Factors on Colorectal Cancer Based on Macrogenomes

NCT06852495Colon Cancer, Rectal Cancer

Dong Peng

Observational

200

Chongqing

2024-11-01

Recruiting

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

NCT06709417Esophageal Squamous Cell Carcinoma (ESCC)

DrugSintilimab

Shanghai Chest Hospital

Phase 2

Shanghai

2024-11-01

Active, closed

The Effect of Environmental Factors on Gastric Cancer Based on Macrogenome

NCT06854146Gastric Cancers, Air Pollution

Dong Peng

Observational

200

Chongqing

2024-11-01

Recruiting

TDLN-sparing RT Plus Immunotherapy and Chemotherapy in Locally Advanced ESCC

NCT06676449Esophageal Carcinoma, Radiotherapy, Immunotherapy

Fudan University

Phase 3

432

Shanghai

2024-11-01

Recruiting

Photoacoustic Tomography in Assessment of Lower Extremity Artery Disease

NCT06579326Lower Extremity, Photoacoustic

Sun Yat-sen University

Observational

200

Guangzhou

2024-11-01

Recruiting

Phase I Study of Umbilical Cord Blood Natural Killer (NK) Cell Therapy for Children With High-risk, R/R Neuroblastoma.

NCT06631391Neuroblastoma

Sun Yat-sen University

Phase 1

Guangzhou

2024-11-01

Recruiting

The Effect of Standard Cognitive-behavioral Therapy+Transcranial Alternating Current on Refractory Insomnia Disorder

NCT06969040Insomnia

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

By invitation

Adjuvant Adebrelimab Plus Apatinib After Chemoradiation in Limited-Stage Small Cell Lung Cancer

NCT06773156Limited-stage Small Cell Lung Cancer (LS-SCLC)

DrugsApatinib·Adebrelimab

Second Affiliated Hospital of Nanchang University

Phase 2

Nanchang

2024-11-01

Not yet open

Noninvasive Assessment of Pulmonary Fluid Levels by Remote Dielectric Sensing Technology to Improve Cardiac InsUfficieney During Ischemia-Reperfusion and Clinical Outcomes in MyocArdiaL Infarction

NCT06671067Acute Myocardial Infarction, Acute Decompensated Heart Failure (ADHF)

Shanghai 10th People's Hospital

Not applicable

2,000

Kaifeng, Zhengzhou, Shanghai

2024-11-01

Recruiting

Clinical Study of SMILE 4.0-VISULYZE in Correcting Refractive Errors

NCT06982807Refractive Surgery, Myopia; Refractive Error

Affiliated Hospital of Nantong University

Not applicable

600

Nantong

2024-11-01

Recruiting

Planed Organ Preservation for Low Rectal Cancer After Neoadjuvant Chemotherapy (OPLAR)

NCT07070622Rectal Cancer

West China Hospital

Phase 3

186

Chengdu

2024-11-01

Recruiting

Venous Congestion And Cognitive Dysfunction After Cardiac Surgery

NCT07483151Intraoperative Venous Congestion And Cognitive Dysfunction After Cardiac Surgery

Zhuan Zhang

Observational

110

Yangzhou

2024-11-01

Recruiting

Digital Early Warning System for Acute Lung Injury in Liver Surgery

NCT07070362Acute Lung Injury(ALI), Liver Cirrhosis, ARDS, Human, MASLD

Beijing Tsinghua Chang Gung Hospital

Observational

3,000

Beijing, Chongqing, Qingdao

2024-11-01

Recruiting

Memory Training in Insomnia With Cognitive Impairment

NCT06969066Cognitive Therapy/Methods, Insomnia Chronic, Cognitive Dysfunction

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

Active, closed

Efficacy of High-flow Nasal Oxygen in Preventing Hypoxia During Gastrointestinal Endoscopy: a Retrospective Cohort Study

NCT06710613Hypoxia

Fengli Liu

Observational

900

Nanchang

2024-11-01

Recruiting

Effect of Different Surgical Approaches of Granulomatous Mastitis

NCT06712524Breast-conserving Plastic Surgery, Granulomatous Mastitis

Hubei Cancer Hospital

Not applicable

240

Wuhan

2024-11-01

Not yet open

A Novel Serological Risk Model for Early Non-invasive Diagnosis of Cholangiocarcinoma

NCT06658587Cholangiocarcinoma

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Observational

Guangzhou

2024-11-01

Not yet open

Smart Technology Facilitated Patient-centered Venous Thromboembolism Management

NCT06350344Venous Thromboembolism, Digital Health, Health Education

Navy General Hospital, Beijing

Not applicable

2,353

Beijing

2024-11-01

Recruiting

CtDNA-guided Maintenance Therapy in Pancreatic Cancer

NCT07054879Pancreatic Cancer

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Observational

Nanjing

2024-11-01

Recruiting

Safety and Efficacy Study of Sorbitol With Neoadjuvant Chemotherapy Combined With Tirellizumab (PD-1 Inhibitor) in Patients With Locally Advanced Gastric Cancer

NCT06826079Gastric Junction Adenocarcinoma, Gastric Cancer, Immunotherapy, Neoadjuvant Therapies

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 2

Wuhan

2024-11-01

Active, closed

Cola Ingestion for Esophageal Bolus Impaction

NCT06652620Esophageal Cancer

Fudan University

Not applicable

Xiamen, Anyang, Yangzhou, Jingdezhen, Shanghai

2024-11-01

Recruiting

The Effects of Tai Chi on Metabolic Dysfunction-associated Fatty Liver Disease in Middle-Aged and Older Adults

NCT06717828Non-Alcoholic Fatty Liver Disease

Fujian Provincial Hospital

Not applicable

250

Fuzhou

2024-11-01

Recruiting

Effects of Relaxation Training and Stimulus Control in Chronic Insomnia Patients

NCT06658171Chronic Insomnia

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

Recruiting

Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus Regions

NCT06705036Pituitary Tumor

Shanghai Zhongshan Hospital

Observational

Shanghai

2024-11-01

Not yet open

A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway

NCT06614751Solid Cancers, BRCA Mutation, HRD Cancer, Breast Cancer

DrugDAT-2645

Danatlas Pharmaceuticals Co., Ltd

Phase 1

112

Beijing, Beijjing

2024-11-01

Active, closed

Neuroimage-guided Dual-target Continuous Theta Burst Stimulation for Generalized Anxiety Disorder

NCT06699706Anxiety, Transcranial Magnetic Stimulation Repetitive

Anhui Medical University

Not applicable

Hefei

2024-11-01

Recruiting

Research on Clinical Recovery and Maintenance Strategies for CHB

NCT06803368Chronic Hepatitis b, Hepatitis B Vaccine

Beijing Municipal Administration of Hospitals

Not applicable

285

Beijing

2024-11-01

Recruiting

Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment Exhaustion

NCT06739395Solid Tumor, Precision Medicine

DrugsVebreltinib Enteric·Dabrafenib·Trametinib·Chidamide

Tianjin Medical University Second Hospital

Phase 2

300

Tianjin

2024-11-01

Recruiting

Effect of Transcranial Direct Current Stimulation on Postoperative Delirium in Elderly Patients

NCT06678529Delirium - Postoperative, Hip Fractures (ICD-10 72.01-72.2)

Huazhong University of Science and Technology

Not applicable

160

Taiyuan

2024-11-01

Recruiting

Postoperative Pain of Robotic, Endoscopic and Open Lateral Neck Dissection

NCT06803732Pain, Postoperative, Thyroid Diseases, Surgery

Shanghai 6th People's Hospital

Observational

600

Shanghai

2024-11-01

Active, closed

Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia Control

NCT06647160Myopia, Progressive

Zhongshan Ophthalmic Center, Sun Yat-sen University

Not applicable

200

Guangzhou

2024-11-01

Recruiting

Study of Risk Factors and Prediction of Blood Clots After Lung Cancer Surgery

NCT07439991Lung Cancer (Diagnosis), Deep Vein Thrombosis (DVT), Venous Thromboembolism (VTE)

The First Hospital of Jilin University

Observational

900

Changchun

2024-11-01

Recruiting

Irinotecan Liposome Combined with S-1 in PD-1/L1 Inhibitor Refractory Recurrent or Metastatic NPC

NCT06657690Recurrent or Metastatic Nasopharyngeal Carcinoma

DrugsIrinotecan liposome·Teysuno

Sun Yat-sen University

Phase 2

Zhuhai

2024-11-01

Recruiting

Randomized Study of Plasma ctDNA Methylation to Guide Adjuvant Chemotherapy Decisions in High-Risk T3N0 Colorectal Cancer

NCT07562711ctDNA, Chemotherapy, Colorectal Cancer

DrugsFolfox·Capecitabine

Fudan University

Phase 2

340

Shanghai

2024-11-01

Recruiting

Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension

NCT07064434Postoperative Pain

General Hospital of Ningxia Medical University

Not applicable

Yinchuan

2024-11-01

Recruiting

Orelabrutinib in Combination with R-CHOP for CD5-positive DLBCL Patients（Rocket Trial）

NCT06647940Diffuse Large B Cell Lymphoma (DLBCL)

DrugsR-CHOP Protocol·R-Chop·Orelabrutinib

Sun Yat-sen University

Phase 2

Guangzhou, Lanzhou, Dongguan, Shantou, Shenzhen, Zhaoqing, Zhuhai

2024-11-01

Recruiting

PET/CT for Trop2 ADC Response Evaluation Cancers

NCT07046689Breast Cancer, Trop2, PET/CT

The First Affiliated Hospital of Xiamen University

Observational

Xiamen

2024-11-01

Recruiting

Randomized Controlled Study of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy in Stage I/Low-Risk Stage II Colorectal Cancer

NCT07562659ctDNA, Colorectal Cancer (CRC), Adjuvant Chemotherapy

DrugCapecitabine

Fudan University

Phase 2

Shanghai

2024-11-01

Recruiting

Impact of Analytic-integrative Cognitive Behavioural Therapy on Acute Insomnia Disorder (Stress)

NCT06967922Acute Insomnia Disorder

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

Recruiting

GzmB-PET/CT to Evaluate Neoadjuvant Therapy Efficacy in Breast Cancer

NCT06725940Breast Cancer Invasive

Shanghai Jiao Tong University School of Medicine

Observational

Shanghai

2024-11-01

Not yet open

Clinical Research of CD19 Targeted CAR-T Cell in Relapsed/ Refractory B-ALL

NCT06641024Acute Lymphoblastic Leukemia, in Relapse, Refractory Acute Lymphoblastic Leukemia

DrugMC-1-50

Chongqing Precision Biotech Co., Ltd

Phase 1

Shanghai

2024-11-01

Recruiting

Bendamustine Combined With Chidamide and Lenalidomide for Relapsed and Refractory PTCL Patients

NCT07072221Peripheral T-cell Lymphoma

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-11-01

Recruiting

SBRT Combined With PD-1 Inhibitor and Chemotherapy in Early-stage TNBC

NCT06627712TNBC - Triple-Negative Breast Cancer

DrugSBRT

West China Hospital

Phase 3

318

Sichuan

2024-11-01

Active, closed

Efficacy and Safety Evaluation of Microfocused Ultrasound Combined With 1550 nm Non-Ablative Fractional Laser for Facial Rejuvenation

NCT07107308Photo-aged Skin

Second Affiliated Hospital of Xi'an Jiaotong University

Not applicable

Xi’an

2024-11-01

Recruiting

Fibrosis Assessment in Myocardial Infarction-associated Ventricular Aneurysm

NCT06994221Acute Myocardial Infarction, Ventricular Aneurysm Following Acute Myocardial Infarction, Myocardial Fibrosis

RenJi Hospital

Observational

Shanghai

2024-11-01

Recruiting

Effect of MIT for CI With Anxiety

NCT06969053Chronic Insomnia, Anxiety Disorders

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-11-01

Active, closed

Microbial Community Characteristics in Intestinal Mucosal Tissue of Patients With CD

NCT06895772Crohn's Disease (CD)

Shandong University

Observational

Jinan

2024-11-01

Recruiting

Cadonilimab Combined With Stereotactic Radiotherapy as Second-line Treatment for Brain Metastases

NCT06702826Non Small Cell Lung Cancer, Brain Metastases, Stereotactic Radiation, Immunotherapy

DrugCadonilimab

Rongrong Zhou

Phase 2

Changsha

2024-11-01

By invitation

Perioperative Treatment Outcomes of Early NSCLC

NCT06610240NSCLC

Shanghai Chest Hospital

Observational

500

Shanghai

2024-11-01

Recruiting

Transcranial Direct Current Stimulation Enhances Dual-task Performance in Stroke

NCT06818240Chronic Stroke

The Hong Kong Polytechnic University

Not applicable

2024-11-01

Recruiting

The Dosing Regimen of Pyrotinib in HER2-positive Advanced First-line Breast Cancer: a Phase I Clinical Study

NCT06770296Breast Cancer

The First Affiliated Hospital with Nanjing Medical University

Phase 1

200

Nanjing

2024-11-01

Active, closed

A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer

NCT06688786Locally Advanced Rectal Cancer (LARC)

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Not applicable

Shanghai

2024-11-01

Recruiting

Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer

NCT06520683Colorectal Cancer, Microsatellite Instability High

DrugTislelizumab

Sun Yat-sen University

Phase 3

180

Guangzhou

2024-11-01

Recruiting

Validating a Medical AI Fine-Tuning Platform for Major Diseases

NCT07795645Chronic Gastritis, Gastric Cancer (GC), Coronary Artery Disease, Stroke

Beijing Friendship Hospital

Observational

96,000

Beijing

2024-11-01

Recruiting

Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC

NCT06500208Breast Cancer

DrugAdebrelimab

Shanghai Jiao Tong University School of Medicine

Phase 2

Shanghai

2024-11-01

Recruiting

Umbilical Cord Blood NK Cell Therapy for High-Risk Pediatric Soft Tissue Sarcoma: Efficacy and Safety Study

NCT06848582Soft Tissue Sarcoma (STS)

Sun Yat-sen University

Not applicable

Guangzhou, Dongguan

2024-11-01

Recruiting

Evaluation of the Efficacy of MACitentan in the Treatment of CoronaryMICrovascular Angina (MACMIC)

NCT06811831Coronary Microvascular Angina, Macitentan

DrugMacitentan

China-Japan Friendship Hospital

Early Phase 1

Beijing

2024-11-01

Recruiting

Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing

NCT06023472Infertility, Genetic Disease, Chromosomal Rearrangement, Aneuploidy

Professor Ernest Hung-Yu Ng

Not applicable

318

Hong Kong

2024-11-01

Recruiting

The Associations of Sleep Disturbance With Therapy Efficacy and Prognosis of Lung Cancer

NCT06975384Lung Cancer, Sleep Disturbance, Immune Checkpoint Inhibitors, Cancer, Treatment-Related

Second Xiangya Hospital of Central South University

Observational

1,270

Changsha

2024-11-01

Recruiting

Chidamide Combined With Brentuximab Vedotin Regimen for CD30+ PTCL Patients

NCT07074457CD30+ Peripheral T-cell Lymphoma

DrugChidamide

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-11-01

Recruiting

Venous Congestion And Delirium After Cardiac Surgery

NCT07285187Intraoperative, Venous Congestion, Postoperative Delirium (POD), Cardiac Surgery

Zhuan Zhang

Observational

120

Yangzhou

2024-11-01

Recruiting

Effects of Cognitive Behavioral Therapy Through a Mobile App on Patients With Refractory Functional Dyspepsia

NCT06756139Functional Dyspepsia, Self-help Mobile Cognitive Behavioral Therapy, Antipsychotic Drug

Air Force Military Medical University, China

Not applicable

Haikou, Xi'an, Mianyang

2024-11-01

Recruiting

Personalized Ultrasound-Guided External Diaphragm Pacing to Improve Outcomes in Invasive Mechanically Ventilated Patients

NCT06609577Respiratory Failure, Mechanical Ventilation

Daishan Jiang

Not applicable

150

Nantong

2024-11-01

Recruiting

Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML

NCT06452732Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia

Peking University People's Hospital

Observational

283

Beijing

2024-11-01

Active, closed

Correlation of Preoperative Indices (serum Vit D, Calcium, Phosphorus, FAR, PLR, SII) on Intraoperative Bleeding in CRS

NCT06737198Chronic Rhinosinusitis (CRS) with and Without Nasal Polyps

Nanjing First Hospital, Nanjing Medical University

Observational

100

Nanjing

2024-11-01

By invitation

Sleep Improvement Therapy Affects Pregnancy Outcomes in Chinese Singletons and Twins by Improving Sleep Quality

NCT06687044Gestational Diabetes, Hypertension in Pregnancy, Preterm Labor, NICU Infants

Jun Wei

Not applicable

300

Shenyang

2024-11-01

Not yet open

Cadonilimab Combined With Anlotinib Followed by Radiotherapy in Recurrent or Metastatic Esophageal Squamous Cell Carcinoma (CAR-RMEC)

NCT06681285Esophageal Carcinoma

DrugsAnlotinib·Cadonilimab

Hebei Medical University Fourth Hospital

Phase 2

Shijiazhuang

2024-11-01

Recruiting

Microfluidic Chip Method Versus Density-gradient Centrifugation Method in IVF

NCT06005311Infertility

Professor Ernest Hung-Yu Ng

Not applicable

1,136

Hong Kong

2024-11-01

Active, closed

Evaluating the Effectiveness of Intervention Based on the Model of Occupational Harmony in Patients With Sleep Disorders

NCT06558929Circadian Rhythm Sleep-Wake Disorder

Peking University First Hospital

Not applicable

Beijing

2024-11-01

By invitation

The Effectiveness of Interventions Targeting Self-Perception of Aging in Older Adults with Subjective Cognitive Decline

NCT06622889Subjective Cognitive Decline (SCD)

Zheng Li

Not applicable

Beijing

2024-11-01

Recruiting

Randomized Trial of Plasma ctDNA Methylation-Guided Adjuvant Therapy in T4N0 and Low-Risk Stage III Colorectal Cancer

NCT07562503ctDNA, Colorectal Cancer, Chemotherapy

DrugCapeox

Fudan University

Phase 2

340

Shanghai

2024-11-01

Not yet open

Intelligent Analysis and Clinical Validation of Cerebral Small Vessel Disease on Magnetic Resonance Imaging：A Multi-center Study

NCT06667635Cerebral Small Vessel Disease

Chinese PLA General Hospital

Observational

1,000

Beijing

2024-11-01

Not yet open

Abnormal Glucose Tolerance in Allogeneic Hematopoietic Stem Cell Transplantation

NCT06704542ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Diabetes Mellitus, Impaired Fasting Glucose

Ruijin Hospital

Observational

1,000

Zhengzhou, Wuhan, Shanghai, Hangzhou, Tianjin

2024-11

Not yet open

Drug Eluting Stenting and Short Dual Antiplatelet Therapy for Preventing Recurrent Stroke in Vertebral Stenosis Registry Study

NCT06683300Vertebral Artery Stenosis

Beijing Tiantan Hospital

Observational

520

Beijing

2024-11

Not yet open

A Clinical Trial to Evaluate the Safety and Tolerability of TQB3911 Tablets in Patients With BCR::ABL Fusion Gene Positive Leukemia

NCT06672263Chronic Myelogenous Leukemia

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 1

120

Beijing, Nanning, Zhengzhou, Shanghai, Hangzhou

2024-11

Not yet open

Neoadjuvant and Adjuvant Sintilimab Combined with Chemoradiotherapy Versus Chemoradiotherapy Alone in Stage TanyN3M0 Nasopharyngeal Carcinoma

NCT06680115Nasopharyngeal Carcinoma (NPC)

DrugSintilimab

First Affiliated Hospital of Guangxi Medical University

Phase 2

150

Nanning

2024-11

Not yet open

Minimal Residual Disease Guiding Adjuvant Therapy in Stage I NSCLC

NCT06709274Non-Small Cell Lung Cancer

DrugsAlectinib·Osimertinib

Guangdong Association of Clinical Trials

Not applicable

342

Dongguan, Foshan, Guangzhou, Shenzhen, Nanning, Guiyang, Wuhan, Changsha

2024-11

Not yet open

A Multicenter, Open Label Phase I Clinical Trial Evaluating the Safety and Pharmacokinetics of TQB2252 Injection in Subjects With Advanced Malignant Tumors

NCT06649656Advanced Cancers

Chia Tai Tianqing Pharmaceutical (Guangzhou) Co., Ltd.

Phase 1

100

Guangzhou

2024-11

Not yet open

Assessing Diabetic Foot Ulcer Microcirculation With High-frequency Contrast Enhanced Ultrasound

NCT06309082Diabetes Mellitus

First Affiliated Hospital of Wenzhou Medical University

Observational

100

Wenzhou

2024-11

Not yet open

Identification Of High-risk Coronary Plaques By Multimodal Intravascular Imaging

NCT06681155Coronary Arterial Disease (CAD), Acute Coronary Syndromes

Chinese PLA General Hospital

Observational

500

Shenzhen, Wuhan, Changchun, Xi'an, Ürümqi, Hangzhou, Beijing

2024-11

Recruiting

Acute Effects of Meteorological Factors and Air Pollution on Cardiovascular Health

NCT06663267Cardiovascular System, Health

The Affiliated Hospital of Hangzhou Normal University

Observational

350,000

Hanzhou

2024-11

By invitation

Association of Nutritional Status With Immune Checkpoint Inhibitor Efficacy in Metastatic Metastatic Esophagogastric Cancer.

NCT06923020Gastric Neoplasm, Esophageal Adenosquamous Carcinoma

Yongxu Jia

Observational

200

Zhengzhou

2024-10-31

Recruiting

A Prospective, Randomized, Controlled Clinical Study on the Prevention of Chemotherapy Related Myelosuppression in Patients with Ewing's Sarcoma Using Trilaciclib

NCT06699472Ewing Sarcoma, Myelosuppression

DrugTrilaciclib

Fudan University

Phase 2

Shanghai

2024-10-31

Not yet open

A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Participants with KRAS G12C Mutation Advanced Solid Tumors

NCT06594874Non-Small Cell Lung Cancer, Advanced Solid Tumors

DrugsHS-10370·Adebrelimab·Pemetrexed·Cisplatin

Jiangsu Hansoh Pharmaceutical Co., Ltd.

Phase 1

350

Wuhan

2024-10-31

Recruiting

RD13-02 Cell Injection in Patients with Relapsed or Refractory CD7-Positive Natural Killer/T Cell Malignancies

NCT06732492NK T-Cell Lymphoma, CART Therapy, CD7-positive Relapsed/Refractory Lymphoid Hematologic Malignancies

DrugRD13

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 1

Wuhan

2024-10-31

Recruiting

Venetoclax Combined with Intensive Therapy for Acute Myeloid Leukemia Patients with Lower Early Peripheral Blast Clearance Rate After Standard Induction Therapy

NCT06643962Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

DrugsAra-C·Cytarabine·Venetoclax

Affiliated Hospital of Nantong University

Not applicable

Nantong

2024-10-31

Not yet open

Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAI

NCT06633718Intra-abdominal Infections

DrugsMeropenem and Pralurbactam·Ceftazidime-avibactam·Metronidazole

Qilu Pharmaceutical Co., Ltd.

Phase 3

786

Hangzhou

2024-10-31

Recruiting

Prone Position Assessed by 3D EIT

NCT07083973ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure

Peking Union Medical College Hospital

Observational

Beijing

2024-10-31

Recruiting

Safety and Efficacy of Mitoxantrone Hydrochloride Liposome Based DCMG Regimen for R/R AML

NCT06741722AML, Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia

Beijing 302 Hospital

Phase 2

Beijing

2024-10-31

Recruiting

A Study to Evaluate the Efficacy and Safety of Combination Therapy of BRII-179, BRII-835 and PEG-IFNα in Participants With Chronic Hepatitis B Virus (HBV) Infection (ENHANCE)

NCT06650852Chronic Hepatitis B Virus (HBV) Infection

DrugsElebsiran·Peg-IFNα

Brii Biosciences Limited

Phase 2

250

Beijing, Guangzhou, Shenzhen, Shanghai, Chengdu, Hangzhou

2024-10-31

Recruiting

Analysis of Influencing Factors of High-Order Aberrations of SMILE With Lenticule Retained

NCT06806085Small-incision Lenticule Extraction (SMILE) Surgery, Corneal Higher-order Wavefront Aberrations, Residual Lenticule

Second Affiliated Hospital of Nanchang University

Observational

Nanchang

2024-10-31

Recruiting

A Stuty on the Treatment and Nursing Care of CIPN Patients With Traditional Chinese Medicine Hot Package

NCT06492083Chemotherapy

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Not applicable

Yiwu

2024-10-30

Not yet open

Risk Stratification and Early Prevention Strategies for Non-compaction of Ventricular Myocardium (CAPTAIN)

NCT06504056Isolated Noncompaction of the Ventricular Myocardium

First Affiliated Hospital Xi'an Jiaotong University

Observational

2,000

Xi'an

2024-10-30

Recruiting

A Study of the ILB-3101 in Patients with Advanced Solid Tumors

NCT06426680Advanced Solid Tumor

Innolake Biopharm

Phase 1

240

Shanghai

2024-10-30

Recruiting

A Study of HS-20124 in Patients with Advanced Solid Tumors

NCT06763159Solid Cancer

Hansoh BioMedical R&D Company

Phase 1

450

Shanghai

2024-10-30

Recruiting

A Prospective Multicenter Clinical Study： IntracOronary neaR-Infrared Spectroscopy and OptIcal Coherence Tomography for Evaluating Coronary vulNerable Plaque in Patients With diabeTes

NCT06649305Coronary Heart Disease (CHD), Diabetes (DM)

Shanghai Zhongshan Hospital

Observational

1,516

Shanghai

2024-10-30

Recruiting

A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

NCT06601335Head and Neck Squamous Cell Carcinoma

DrugsLigufalimab·Ivonescimab

Akeso

Phase 3

510

Wuhan, Chengdu

2024-10-30

Recruiting

Efficacy and Safety of CD19 UCAR T Cells in Refractory Systemic Lupus Erythematosus

NCT06691152Systemic Lupus Erythematosus

The Children's Hospital of Zhejiang University School of Medicine

Phase 1

Hangzhou

2024-10-30

Active, closed

Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia

NCT06497062Acute Myeloid Leukemia

DrugsSonrotoclax·Ara-C·Cytarabine·Azacitidine

Shanghai Jiao Tong University School of Medicine

Phase 2

Shanghai

2024-10-30

By invitation

Intelligent Accelerated MRI for Pediatric Abdominal Pain

NCT07164651Pediatric Abdominal Pain

Yaqi Shen，MD，PhD

Observational

150

Wuhan

2024-10-30

Recruiting

A Study of GNC-077 in Patients With Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors

NCT06609187Breast Cancer, Solid Tumor

DrugGNC-077

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Beijing

2024-10-30

Recruiting

A First-in-Human Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of a Novel CRISPR RNA-editing Therapy in Patients with Mecp2 Duplication Syndrome, a Rare Orphan Disease (HERO)

NCT06615206MECP2 Duplication Syndrome

HuidaGene Therapeutics Co., Ltd.

Not applicable

Beijing

2024-10-30

Recruiting

Demethylating Agents Combined With Venetoclax for High-risk T-cell Lymphoblastic Lymphoma/Leukemia Post-Transplant Relapse Prevention

NCT06686108T-cell Acute Lymphoblastic Leukemia, ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Relapse

DrugsAzacitidine (AZA) Days 1 - 5·Decitabine·Venetoclax

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Phase 2

Shanghai

2024-10-30

Active, closed

NCRT Combined With Sequential Perioperative PD-1 Inhibitor for LAESCC

NCT06762158Esophageal Squamous Cell Carcinoma (ESCC)

RenJi Hospital

Not applicable

Shanghai

2024-10-30

Recruiting

Multicenter iTBS Neuromodulation for PTSD Treatment

NCT06434766Posttraumatic Stress Disorder

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

140

Shanghai, Hangzhou, Ningbo

2024-10-30

Not yet open

Anlotinib Plus Benmelstobart and AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer (ALTER-PA-001)

NCT06621095Pancreatic Cancer, First-line, Metastatic Pancreatic Cancer

DrugsBenmelstobart·Anlotinib·Nab-paclitaxel·Gemcitabine

RenJi Hospital

Phase 2

104

Shanghai

2024-10-30

Not yet open

The Effectiveness and Safety of Glofitamab in Real-World Clinical Practice Among Chinese Adult Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Prospective, Observational, Multicenter Study

NCT06656234Diffuse Large B Cell Lymphoma (DLBCL)

DrugsGlofitamab·Obinutuzumab

Ruijin Hospital

Observational

200

Shanghai

2024-10-30

By invitation

A Multicenter, Randomized, Controlled Trial of Prednisone Combined With Ursodeoxycholic Acid in the Treatment of Primary Biliary Cholangitis With Moderate to Severe Interface Hepatitis Characteristics

NCT06591468Primary Biliary Cholangitis (PBC)

DrugsUDCA·Prednisone

Han Ying

Phase 2/3

244

Guangzhou, Xi'an

2024-10-30

Not yet open

Safety and Efficacy of Edaravone Dexborneol for Acute Ischemic Stroke

NCT06645522Acute Ischemic Stroke

DrugEdaravone dexborneol

Yi Yang

Phase 4

1,200

Changchun

2024-10-30

Recruiting

Evaluation of the Effectiveness and Safety of Laparoscopic Assisted Mastectomy With Preservation of Nipple and Areola, Immediate One-step Breast Reconstruction With Pectoral Muscle Prosthesis and Patch, and Simultaneous Autologous Fat Transplantation

NCT07037537Breast Cancer Patients

Henan Cancer Hospital

Not applicable

Zhengzhou

2024-10-30

Not yet open

Molecular Subtype Combined with Early Minimal Residual Disease to Optimize the Treatment of Newly Diagnosed Acute Myeloid Leukemia

NCT06652685Acute Myeloid Leukemia (AML)

Ruijin Hospital

Phase 2

218

Shanghai

2024-10-30

Recruiting

Evaluation of Safety, Efficacy, and Pharmacokinetics of BT-114143 Injection in Patients With Abnormal Uterine Bleeding

NCT07169214Abnormal Uterine Bleeding

DrugBT-114143

ScinnoHub Pharmaceutical Co., Ltd.

Phase 1

Beijing

2024-10-30

Recruiting

Spironolactone Improved Children With Gene Mutations Related to NCOR

NCT06678685NCOR Gene Mutations, Spironolactone, ASD

DrugSpironolactone

Qilu Hospital of Shandong University

Phase 2/3

Jinan

2024-10-30

Active, closed

Recovery and Safety After Epidural Spinal Cord Stimulation in People With Spinal Cord Injury

NCT07900490Spinal Cord Injury

Hainan University

Observational

Haikou

2024-10-30

Not yet open

A Prospective Cohort of Patients With Cervical/Intracranial Arteries Stenosis in China

NCT06595342Cervical Artery Stenosis, Intracranial Artery Stenosis

The First Hospital of Jilin University

Observational

60,000

Changchun

2024-10-30

Recruiting

A Multi-center Open Label Prospective Study on Early Initiation of Targeted-release Formulation of Budesonide in Patients With Primary IgA Nephropathy

NCT06676007IgA Nephropathy (IgAN), Early Initial Therapy

Sichuan Provincial People's Hospital

Observational

200

Chengdu

2024-10-30

Recruiting

Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors

NCT06819215Cancer, Neoplasms, Neoplasms, Breast, Tumor

Zhejiang Yangli Pharmaceutical Technology Co., Ltd.

Phase 1/2

188

Jinan

2024-10-30

Active, closed

A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination With Pembrolizumab as First-Line Treatment for PD-L1 Negative Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

NCT06711900Non-Small Cell Lung Cancer

DrugsSacituzumab tirumotecan·Pemetrexed·Cisplatin·Carboplatin

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Phase 3

432

Beijing, Changchun, Changcun, Changsha, Chengdu, Chongqing, Dalian, Fuzhou

2024-10-30

Active, closed

A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

NCT06644768Non-small Cell Lung Cancer, Lung Cancer

DrugsValemetostat·Valemetostat Tosylate·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 1/2

137

Changchun, Hangzhou, Harbin, Jiamusi, Shanghai, Tiyuan, Zhengzhou

2024-10-30

Active, closed

Zanubrutinib Plus Rituximab as Front-line Treatment for Mucosa-associated Lymphoid Tissue Lymphoma (MALT)

NCT06647732Mucosa-associated Lymphoid Tissue Lymphoma (MALT)

DrugsZanubrutinib·Rituximab

Sun Yat-sen University

Phase 2

Guangzhou

2024-10-30

Recruiting

Neoadjuvant Radiotherapy for Locally Advanced Unresectable Thymoma

NCT06924619Locally Advanced Thymoma

DrugCisplatin

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

178

Hangzhou

2024-10-30

Recruiting

Effect of Goal-Oriented Albumin Infusion on Postoperative Complication Management in Gastric Cancer Surgery

NCT07119463Postoperative Hypoalbuminemia, Postoperative Complications, Gastric Cancer

The First Hospital of Jilin University

Phase 2

112

Changchun

2024-10-29

Recruiting

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

NCT06663332Crohns Disease, Colitis, Ulcerative, Arthritis, Psoriatic, Arthritis, Juvenile

DrugGuselkumab

Janssen Research & Development, LLC

Phase 3

196

Beijing, Changzhou, Hangzhou, Shanghai, Shenyang

2024-10-29

By invitation

Adaptive Cognitive Training on Cognitive Function in Elderly Diabetes Patients in the Community

NCT06524388Cognition, Diabetes Mellitus, Type 2, Aging

Fanfan Zheng

Not applicable

120

Beijing

2024-10-29

Recruiting

An Open-label, Multi-center, Dose-escalation and Cohort Expansion Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile and Efficacy of ACR246 in Patients With Advanced Solid Tumors

NCT06238401Advanced Solid Tumors

Hangzhou Adcoris Biopharmacy Co., Ltd

Phase 1

Beijing, Zhejiang, Shandong, Shanghai

2024-10-29

Recruiting

Treating Loneliness In The Older Adult With Depression With tDCS

NCT06658795Major Depressive Disorder, Loneliness

Guangzhou Psychiatric Hospital

Not applicable

180

Guangzhou

2024-10-29

By invitation

Evaluation of [68Ga]DOTA-IR-780-C-4 in PET Imaging Studies for PSMA-Positive Prostate Cancer Patients

NCT07162779PET CT

Affiliated Hospital of Jiangnan University

Not applicable

Wuxi

2024-10-29

By invitation

Adaptive Cognitive Training on Cognitive Function in Elderly Hypertension Patients in the Community

NCT06512922Hypertension, Condition, Aging

Peking University

Not applicable

120

Beijing

2024-10-29

Active, closed

An Exploratory Study to Evaluate the Tolerability and Safety of MWAV201 in Subjects With Wilson Disease

NCT06663878Wilson Disease

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Not applicable

Shanghai

2024-10-28

Recruiting

Home- vs Hospital-based Care of Anti-VEGF Treatment for Diabetic Macular Edema: Non-inferiority RCT

NCT06610747Diabetic Macular Edema

Zhongshan Ophthalmic Center, Sun Yat-sen University

Not applicable

308

Dongguan, Foshan, Guangzhou

2024-10-28

Active, closed

Clinical Safety and Efficacy of Umbilical Cord Mesenchymal Stromal Cells-derived Exosomes in Patients With Parkinson's Disease

NCT07923838Parkinson Disease (PD)

Shanghai Jiao Tong University School of Medicine

Phase 1/2

Shanghai

2024-10-28

Recruiting

A Clinical Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma (KYLIN-02)

NCT06618664Advanced Hepatocellular Carcinoma

DrugsSHR-8068·Adebrelimab·Sintilimab·Bevacizumab

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 3

590

Hefei

2024-10-28

Active, closed

Clinical Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of HSK31858 in Healthy Subjects

NCT07134478Healthy Subjects

Haisco Pharmaceutical Group Co., Ltd.

Phase 1

Shanghai

2024-10-28

Active, closed

Neoadjuvant Camrelizumab With Palbociclib for Resectable Esophageal Squamous Cell Carcinomas

NCT06654297Esophageal Squamous Cell Carcinoma

DrugsPalbociclib·Camrelizumab

West China Hospital

Phase 1

Chengdu

2024-10-27

Recruiting

Rapid dFLC Response Predict CHR in AL Amyloidosis

NCT06627309Systemic AL Amyloidosis

DrugsDara·Bortezomib·Dexamethasone·Cyclophosphamide

Peking University People's Hospital

Observational

Beijing, Harbin, Nanjing, Shenyang, Xi'an

2024-10-26

Recruiting

A Fast, Quiet, Artificial Intelligence-based PET/MR Solution for Paediatric Diseases

NCT06709690Paediatric Patients

Ruijin Hospital

Observational

Shanghai

2024-10-25

Not yet open

Levothyroxine Intervention in Pregnant Women with TSH （2.5 MIU/L-upper Limit of Reference Range） and Negative Thyroid Peroxidase Antibody

NCT06653907Thyroid Abnormalities, Pregnant Woman, Pregnancy Outcomes

DrugLevothyroxine Sodium (LT4)

Yang ZHANG

Phase 4

400

Shijiazhuang

2024-10-25

Recruiting

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Qifangfeixian Granules in the Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)

NCT06674148Interstitial Lung Disease, Qifangfeixian Granules

Huilan Zhang

Phase 2/3

124

Wuhan

2024-10-25

Recruiting

Clinical Application of FL-091 Radionuclide Imaging in Diagnosis and Staging of Malignant Tumors

NCT06977945Malignant Tumors With Positive NTSR1 Expression

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

100

Wuhan

2024-10-25

Recruiting

Effects of Real-time Continuous Glucose Monitoring System on Hospital-to-home Transitional Blood Glucose Control

NCT06591286Diabetes Mellitus, Type 2

Shanghai 6th People's Hospital

Not applicable

150

Shanghai

2024-10-25

Not yet open

Comparing the Safety and Cosmetic Outcomes Between Laparoscopic Versus Traditional Open Breast-conserving Surgery

NCT06671249Breast Cancer

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

184

Hangzhou

2024-10-25

Recruiting

Evaluation of the Safety, Tolerability, and Efficacy of LE051 in Patients With Duchenne Muscular Dystrophy

NCT06900049Duchenne Muscular Dystrophy (DMD)

Shanghai Jiao Tong University School of Medicine

Early Phase 1

Shanghai

2024-10-24

Recruiting

Phase 1/2 Clinical Study of HY07121 Powder for Solution for Infusion in Patients With Advanced Solid Tumors

NCT06639256Safety, Tolerability, Efficacy

Sichuan Huiyu Pharmaceutical Co., Ltd

Phase 1/2

258

Jinan

2024-10-24

Not yet open

A Study on the Safety and Efficacy of BST08 in Treating Advanced Non-Small Cell Lung Cancer

NCT06643910Non-small Cell Lung Cancer

BioSyngen Pte Ltd

Not applicable

Shenzhen

2024-10-24

Recruiting

Comparing the Efficacy of Domestic Versus Imported Hearing Aids in ARHL

NCT06882889Age-related Hearing Loss, Hearing Loss, Sensorineural

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not applicable

Guangzhou

2024-10-24

Recruiting

Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC

NCT06637163Esophageal Squamous Cell Carcinoma

DrugsBenmelstobart·Paclitaxel·Carboplatin

Shanghai Zhongshan Hospital

Phase 2

100

Shantou, Shenyang, Shanghai, Tianjin, Hangzhou

2024-10-24

Recruiting

Mecapegfilgrastim for Prevention of Chemotherapy-Induced Neutropenia in Advanced Breast Cancer

NCT07899099Breast Cancer, Chemotherapy-induced Neutropenia

Zheng Yabing

Observational

200

Hangzhou

2024-10-24

Recruiting

Gemcitabine Hydrochloride, Cisplatin, Nab-Paclitaxel, and Durvalumab in Treating Patients With Locally Advanced or Metastatic Gallbladder Cancer

NCT06591650Gallbladder Cancer Unresectable

DrugsDurvalumab·Nab-paclitaxel·Gemcitabine·Cisplatin

Fudan University

Phase 2

Shanghai

2024-10-24

Active, closed

Standard Immunosuppressive Therapy Combined With Romiplostim N01 as First-line Treatment for Severe Aplastic Anemia

NCT06613880Aplastic Anemia, TPO Receptor Agonists

DrugIpilimumab

Institute of Hematology & Blood Diseases Hospital, China

Phase 2

Tianjin

2024-10-24

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Antitumor Activity of ALK201 in Participants With Advanced Solid Tumors

NCT06656390Advanced Cancer, Advanced Solid Tumors

Shanghai Allink Biotherapeutics Co., Ltd.

Phase 1/2

202

Hefei, Fuzhou, Xiamen, Guangzhou, Shantou, Nanning, Chengde, Harbin

2024-10-24

Recruiting

An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease

NCT06379646Systemic Lupus Erythematosus, Systemic Sclerosis, Inflammatory Myopathy, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

China Immunotech (Beijing) Biotechnology Co., Ltd.

Not applicable

Shanghai

2024-10-24

Active, closed

A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

NCT06653153Alzheimer's Disease

DrugRemternetug

Eli Lilly and Company

Phase 3

1,400

Beijing, Changchun, Changsha, Chengdu, Guangzhou, Hefei, Jinan, Luoyang

2024-10-24

Recruiting

Changes in Regional Ventilation-Perfusion Match Following Percutaneous Transluminal Angioplasty for Arteriovenous Graft Thrombosis

NCT07613632Arteriovenous Graft Thrombosis, End Stage Renal Disease on Dialysis

First Affiliated Hospital of Wannan Medical College

Observational

Wuhu

2024-10-24

Recruiting

A Study of OL-101 Injection in Patients with Relapsed or Refractory Multiple Myeloma (RRMM)

NCT06644118Multiple Myeloma

Zhejiang University

Phase 1

Beijing, Xi’an, Hangzhou

2024-10-23

Active, closed

Phase I Study of WJ47156 Monotherarpy and in Combination With Other Therapy in Advanced Solid Tumors

NCT06571422Advanced Malignant Solid Tumors

DrugsJS207·JS001·Bevacizumab

Shanghai Junshi Bioscience Co., Ltd.

Phase 1

Guangzhou

2024-10-23

Recruiting

Value of Super-resolution Ultrasonography in Differentiating Benign and Malignant Lymph Nodes

NCT07155954Lymphadenopathy, Lymphnode Metastasis, Lymphoma, Lymphatic Tuberculosis

Peking University Third Hospital

Observational

779

Beijing

2024-10-23

Recruiting

A Clinical Study of JMT101 in Combination With Osimertinib Versus Osimertinib Alone as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Sensitive Mutations

NCT06735391Locally Advanced or Metastatic Non-squamous NSCLC, Harboring EGFR Sensitive Mutations NSCLC, Previously Untreated Systematically NSCLC

DrugsJMT101·Osimertinib

Shanghai JMT-Bio Inc.

Phase 3

516

Guangzhou

2024-10-23

Active, closed

A Study of Single Dose of LP-003 in Healthy Adult Subjects

NCT06604949Chronic Spontaneous Urticaria

DrugLP-003

Longbio Pharma

Phase 1

Shanghai

2024-10-23

Recruiting

Clinical Trial of 13-Valent Pneumococcal Conjugate Vaccine

NCT06617715Pneumococcal Infectious Disease

DrugPrevnar

Sinovac Life Sciences Co., Ltd.

Phase 3

3,080

Zhengzhou

2024-10-23

Recruiting

The Effect of Coffee on Energy Expenditure and Caffeine Metabolism

NCT06712511Healthy

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Not applicable

Shenzhen

2024-10-23

Recruiting

Arsenous Acid for Refractory Triple-Negative Breast Cancer

NCT06678048Breast Cancer

Sun Yat-sen University

Phase 2

Guangzhou

2024-10-23

Recruiting

Sintilimab Plus AVD in Pediatric Low/Moderate Risk Hodgkin Lymphoma: A Phase II Study

NCT06848569Classical Hodgkin Lymphoma

DrugSintilimab

Sun Yat-sen University

Phase 2

Guangzhou

2024-10-23

Recruiting

A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMV

NCT06862089Retained Products of Conception, Miscarriage, Conservative Management

Fu Xing Hospital, Capital Medical University

Observational

120

Beijing

2024-10-23

Recruiting

The Effects of the Control Strategies of Wearable Lower Limb Rehabilitation Robots

NCT07037849Stroke, Gait Training, Gait Disorders

Eighth Affiliated Hospital, Sun Yat-sen University

Not applicable

Shenzhen

2024-10-23

Recruiting

OBINOTUZUMAB Versus Cyclophosphamide + Glucocorticoids in Primary Membranous Nephropathy(Blossom Study)

NCT06781944Primary Membranous Nephropathy

DrugObinutuzumab

Huashan Hospital

Phase 3

144

Shanghai

2024-10-23

Recruiting

The Effect of Coffee on People with High Intensity Exercise and the Characteristics of Caffeine Metabolism

NCT06712667Healthy

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Not applicable

Shenzhen

2024-10-23

Recruiting

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

NCT06629779Metastatic Castration-Resistant Prostate Cancer

DrugsMevrometostat·Xtandi·Enzalutamide

Pfizer

Phase 3

900

Wuhu, Beijing, Fuzhou, Guangzhou, Shantou, Guilin, Xinxiang, Zhengzhou

2024-10-22

Recruiting

Effectiveness of Enhanced External Counterpulsation for Post-acute Stroke Patients

NCT06711003Cerebrovascular Accident (CVA)

China Medical University Hospital

Not applicable

110

2024-10-22

Recruiting

QL0911 for the Treatment of Cancer Treatment-Induced Thrombocytopenia

NCT06456528Cancer Treatment-Induced Thrombocytopenia

Qilu Pharmaceutical Co., Ltd.

Phase 2/3

235

Harbin, Nanjing

2024-10-22

Recruiting

INTERSTELLAR - International Study Evaluating Lupus Outcomes After Anifrolumab Real World Use

NCT06314282Systemic Lupus Erythematosus (SLE)

AstraZeneca

Observational

200

Guangzhou, Hong Kong, Shenzhen, Zhongshan, Zhuhai

2024-10-22

Recruiting

Application of Amide Proton Transfer-Weighted Imaging in Predicting Pathological Complete Response After Neoadjuvant Therapy of Rectal Cancer

NCT06719414Rectal Cancer

Sixth Affiliated Hospital, Sun Yat-sen University

Observational

320

Guangzhou, Maoming

2024-10-22

Recruiting

Sintilimab With P-GEMOX Versus the P-GEMOX in the Teatment of Advanced-stage Extranodal Natural Killer/T Cell Lymphoma

NCT06583083Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

DrugsP-GemOx·Pegaspargase·Sintilimab·Oxaliplatin

Sun Yat-sen University

Phase 2

Guangzhou

2024-10-22

Active, closed

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

NCT06660563Lymphoma, Non-Hodgkin

DrugsJNJ-75348780·JNJ-80948543

Janssen Research & Development, LLC

Phase 1

2024-10-22

Not yet open

Levofloxacin Plus Metronidazole Suppositories Versus Levofloxacin Co-administered with Metronidazole Tablets in Chronic Endometritis

NCT06650540IVF

DrugLevofloxacin

Peking University Third Hospital

Not applicable

800

Beijing

2024-10-22

Recruiting

A Study in Chinese Patients With Acquired Blepharoptosis

NCT06683651Blepharoptosis

Santen Pharmaceutical Co., Ltd.

Phase 3

180

Hefei, Beijing, Shantou, Guiyang, Zhengzhou, Ha’erbin, Wuhan, Xiangyang

2024-10-22

Active, closed

A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).

NCT06551324Metastatic Castrate Resistant Prostate Cancer (mCRPC)

DrugsMevrometostat·Xtandi·Taxotere·Enzalutamide

Pfizer

Phase 3

609

Wuhu, Beijing, Chongqing, Fuzhou, Lanzhou, Guangzhou, Guilin, Wuhan

2024-10-21

Recruiting

Large Fraction Radiation Therapy Combined With Lenalidomide, and Glofitamab in Refractory Relapsed DLBCL

NCT06651853Diffuse Large B-cell Lymphoma, Relapsed and Refractory

The First Affiliated Hospital of Xiamen University

Phase 2

Xiamen

2024-10-21

Active, closed

A Clinical Trial With KJ103 in Anti-GBM Disease

NCT06607016Anti-Glomerular Basement Membrane Disease

DrugCyclophosphamide

Shanghai Bao Pharmaceuticals Co., Ltd.

Phase 2

Beijing

2024-10-21

Recruiting

A Study of Tumor-Treating Fields in Combination With Durvalumab and Gemcitabine/Cisplatin in Biliary Tract Cancers

NCT06611345Biliary Tract Cancers (BTC)

DrugsDurvalumab·Gemcitabine·Cisplatin

Jiangsu Healthy Life Innovation Medical Technology Co., Ltd

Not applicable

Hefei

2024-10-21

Recruiting

Opioid-free Anesthesia Protocol for Neurosurgical Supratentorial Tumor Resection

NCT06607029Supratentorial Tumors

Beijing Tiantan Hospital

Not applicable

170

Beijing

2024-10-21

Recruiting

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

NCT06623422Carcinoma, Non-Small-Cell Lung

DrugsIntismeran autogene·Paraplatin·Taxol·Pemetrexed

Merck Sharp & Dohme LLC

Phase 3

680

2024-10-21

Recruiting

Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer

NCT06649331Advanced Breast Cancer, Metastatic Breast Cancer, Triple Negative Breast Cancer (TNBC), HER2-negative Breast Cancer

DrugsSHR-A1921·SHR-A2009·Famitinib·9MW2821

Fudan University

Phase 2

160

Shanghai

2024-10-21

Recruiting

A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial Hypertension

NCT06554301Pulmonary Arterial Hypertension

China National Center for Cardiovascular Diseases

Phase 1

Beijing

2024-10-20

Not yet open

The Efficacy and Safety of Treatment With Telitacicept in Primary Membranous Nephropathy

NCT06614985Primary Membranous Nephropathy

DrugsTelitacicept·Prednisone·Cyclophosphamide

Renmin Hospital of Wuhan University

Phase 2

172

Wuhan

2024-10-20

Recruiting

The Value of 68Ga-grazytracer PET in Monitoring Responses to Immunotherapy of Gastrointestinal Malignancies

NCT06644274Gastrointestinal Malignancies

Ruijin Hospital

Observational

Shanghai

2024-10-20

Not yet open

Clinical Study of Radiotherapy Combined With Camrelizumab and Apatinib in the Treatment of Liver Cancer Patients .

NCT06632522Liver Cancer

DrugCamrelizumab and apatinib

Beijing Tsinghua Chang Gung Hospital

Phase 2

Beijing

2024-10-20

By invitation

Clinical Classification and Imaging Markers in Patients of Obesity

NCT06649071Obesity, fMRI, Clinical Classification

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Observational

100

Nanjing

2024-10-20

Recruiting

Neoadjuvant Therapy in Cervical Cancer

NCT06558682Uterine Cervical Neoplasms

Qilu Hospital of Shandong University

Not applicable

Jinan

2024-10-20

By invitation

Health Behavior Management Program for Patients With Coronary Heart Disease

NCT07330882Coronary Disease

The First Affiliated Hospital of Bengbu Medical University

Not applicable

200

Bengbu

2024-10-20

Recruiting

TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas

NCT06640582Brain Tumor, Brain Metastases, Brain Cancer, Glioma

DrugsTumor Infiltrating Lymphocytes·Aldesleukin·Fludarabine·Cyclophosphamide

Essen Biotech

Phase 1/2

Beijing

2024-10-20

Active, closed

AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced Biliary Tract Cancer

NCT06591520Biliary Tract Cancer

Akeso

Phase 3

682

Harbin, Shanghai

2024-10-20

Recruiting

Ultrasound-Enhanced Delivery of Compound TXA Solution in Melasma

NCT07202156Melasma (Facial Melasma)

The First Affiliated Hospital with Nanjing Medical University

Not applicable

Nanjing

2024-10-20

Recruiting

Targeting CD5 CAR-T Cells in the Treatment of r/r CD5+ T-ALL

NCT06633354T-Acute Lymphoblastic Leukemia

Zhejiang University

Early Phase 1

Hangzhou

2024-10-20

Recruiting

Targeting CD5 CAR-T Cells in the Treatment of r/r CD5+ T-lymphoma

NCT06633341T-lymphoblastic Lymphoma

Zhejiang University

Early Phase 1

Hangzhou

2024-10-20

Active, closed

An Open Label Study of Gene Therapy Product (Vesemnogene Lantuparvovec) in Spinal Muscular Atrophy

NCT06288230Spinal Muscular Atrophy

Lantu Biopharma

Phase 1/2

Kunming

2024-10-20

Recruiting

CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia

NCT06633328Aplastic Anemia

Zhejiang University

Early Phase 1

Hanzhou

2024-10-20

Recruiting

Study on the Impact of Electroacupuncture Combined With Self-Acupressure on the Quality of Life of Patients With Early-Stage Breast Cancer Undergoing Chemotherapy

NCT06601621Electroacupuncture, Quality of Life (QOL), Acupressure, Breast Cancer

Jiuda Zhao

Not applicable

192

Xining

2024-10-19

Recruiting

The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia

NCT06458257Acute Myeloid Leukemia

Ruijin Hospital

Observational

Shanghai

2024-10-19

Recruiting

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

NCT06598800Advanced Solid Tumor

BeOne Medicines

Phase 1

153

Beijing, Chongqing, Fuzhou, Guangzhou, Nanning, Shijiazhuang, Harbin, Wuhan

2024-10-18

Active, closed

Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation

NCT06780930Residual or Recurrent Grade 2 IDH Mutant Glioma

DrugVorasidenib

Servier

Phase 3

Shenzhen, Chengdu, Beijing, Shanghai, Xi'an

2024-10-18

Recruiting

Correlation Analysis of POD and pNCD in Elderly Patients With Gastrointestinal Neoplasms

NCT06466096Postoperative Delirium, Postoperative Neurocognitive Disorder, Gastrointestinal Surgery

Xuanwu Hospital, Beijing

Observational

165

Beijing

2024-10-18

Recruiting

PRospective Observation on CErebral microvaScular Structure and Function

NCT06579677Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases, Cognitive Dysfunction, Cerebrovascular Disorders

Beijing Tiantan Hospital

Observational

3,500

Beijing

2024-10-18

Recruiting

A Study to Evaluate the Diagnostic Efficacy of 68Ga- MY6349 PET/CT in Patients With Tumours

NCT06770478Tumour of Epithelial Origin, 68Ga-MY6349

Xijing Hospital

Not applicable

Xi'an

2024-10-18

Recruiting

Efficacy and Safety Study of Endovascular Treatment of Asymptomatic Carotid Artery Stenosis

NCT06899399Asymptomatic Carotid Artery Stenosis

Beijing Tiantan Hospital

Not applicable

982

Beijing

2024-10-18

Recruiting

Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment

NCT06698718Periodontitis

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

Hangzhou

2024-10-18

Recruiting

A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

NCT06544499Primary Immune Thrombocytopenia (ITP)

DrugEfgartigimod

argenx

Phase 3

Beijing, Bengbu, Chengde, Hohhot, Huai'an, Huizhou, Tianjin, Wuhan

2024-10-18

Recruiting

Prevention of Recurrence and Metastasis of Colorectal Cancer by Comparing Huaier With Capecitabine Monotherapy

NCT06090994Colorectal Cancer

DrugsHuaier·Capecitabine

Fudan University

Phase 4

756

Harbin, Changzhou, Nanjing, Yangzhou, Shanghai, Hangzhou, Ningbo

2024-10-18

Recruiting

Study on Topping-off Technique for Treating LDD

NCT06650046Lumbar Degenerative Disease

Qianfoshan Hospital

Not applicable

100

Jinan

2024-10-18

Recruiting

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

NCT06662786Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Irinotecan

Janssen Research & Development, LLC

Phase 3

1,000

Beijing, Changchun, Changsha, Guangzhou, Hangzhou, Harbin, Huizhou, Nanchang

2024-10-18

Recruiting

Efficacy of Probucol Combined with Statins Treatment for Ischemic Stroke

NCT06604117Ischemic Stroke, Atherosclerosis of Artery, Lipid Disorder, Statin

DrugProbucol

Xuanwu Hospital, Beijing

Observational

200

Xicheng District

2024-10-17

Active, closed

A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)

NCT06643481Amyotrophic Lateral Sclerosis (ALS)

DrugVHB937

Novartis Pharmaceuticals

Phase 2

251

Beijing

2024-10-17

Recruiting

First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2)

NCT06730373HER2-positive Gastric Cancer, Metastatic Gastric Cancer, Unresectable Gastric Carcinoma

DrugsTeysuno·Disitamab Vedotin·Trastuzumab·Adrucil

Qilu Hospital of Shandong University

Phase 2

110

Zhengzhou, Binzhou, Dongying, Jinan, Jining, Liaocheng, Linyi, Qingdao

2024-10-17

Active, closed

Neoadjuvant Sunvozertinib in Stage II-IIIB Non-small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutation.

NCT07274761Potentially Resectable EGFR Exon 20 Insertion Non-Small Cell Lung Cancer, Non Small Cell Lung Cancer

DrugSunvozertinib

Shanghai Pulmonary Hospital, Shanghai, China

Phase 2

Shanghai

2024-10-17

Recruiting

Application of Platelet-rich Plasma (PRP) in Reproductive Medicine

NCT06645379Premature Ovarian Insufficiency, Intrauterine Adhesion, Poor Ovarian Response, Repeated Implantation Failure

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Not applicable

300

Yiwu

2024-10-17

Recruiting

Blinatumomab Plus Reduced-dose Chemotherapy in Treating B-ALL

NCT06742515Precursor B-Cell Acute Lymphoblastic Leukemia

DrugBlinatumomab

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-10-17

Recruiting

An Investigator-initiated Clinical Study of LM303 Injection for the Treatment of Advanced Solid Tumours

NCT06695689Solid Tumor

Suzhou BlueHorse Therapeutics Co., Ltd.

Early Phase 1

Tianjin

2024-10-17

Recruiting

HRYZ-T102 TCR-T Cell for AFP Positive Advanced HCC and Other Solid Tumors

NCT06515314Hepatic Cell Carcinoma

Shanghai Ruiliyuan Biotechnology Co., Ltd.

Phase 1

Shanghai

2024-10-17

Active, closed

A Study of Dostarlimab in Participants With Untreated Locally Advanced Rectal Cancer in China

NCT06640049Neoplasms, Rectal

DrugDostarlimab

GlaxoSmithKline

Phase 2

Chengdu, Chongqing, Guangzhou, Hangzhou, Jinan, Kunming, Shanghai

2024-10-17

Active, closed

Mass Balance Clinical Trial of SIM0270

NCT06654791Healthy Participants

Jiangsu Simcere Pharmaceutical Co., Ltd.

Phase 1

Jinan

2024-10-17

Recruiting

A Study of BL-B01D1 in Patients With Recurrent Glioblastoma

NCT06598787Recurrent Glioblastoma

DrugIza-bren

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 2

Beijing

2024-10-17

Recruiting

The Efficacy and Safety of Different Combination Regimens of Inetetamab in First-line Treatment of HER2 Positive Metastatic Breast Cancer

NCT06641544Metastatic Breast Cancer

DrugInetetamab

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase 4

200

Shanwei

2024-10-17

Recruiting

Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus

NCT06585514Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN)

Beijing GoBroad Hospital

Phase 1/2

Beijing

2024-10-17

Recruiting

Long-term Impact of Inhaled Tobramycin for Pseudomonas Aeruginosa Eradication in Bronchiectasis (ERASE II)

NCT06760273Bronchiectasis Adult

Shanghai Pulmonary Hospital, Shanghai, China

Observational

364

Hefei, Beijing, Chongqing, Fuzhou, Guangzhou, Shenzhen, Zhanjiang, Nanning

2024-10-16

Active, closed

Acute Effects of Low Temperature Exposure on Respiratory System

NCT06652932Lung Function

Fudan University

Not applicable

Shanghai

2024-10-16

Recruiting

Evaluate the Safety and Preliminary Efficacy of EXG110 in Subjects With Fabry Disease

NCT06539624Fabry Disease

The Children's Hospital of Zhejiang University School of Medicine

Not applicable

Shanghai, Hangzhou

2024-10-16

Recruiting

Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

NCT06802666Locally Advanced Rectal Cancer, Neoadjuvant Therapy

DrugsIvonescimab·Capecitabine·Oxaliplatin

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 2

Hubei

2024-10-16

Recruiting

Safety and Efficacy of Meplazumab in Patients With Coronary Artery Disease

NCT06572267Coronary Artery Disease

Xijing Hospital

Phase 2

Xi'an

2024-10-16

Recruiting

A Study of GNC-077 in Patients With Locally Advanced or Metastatic Non-small-cell Lung Cancer and Other Solid Tumors

NCT06612840Non-small Cell Lung Cancer, Solid Tumor

DrugGNC-077

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Shanghai

2024-10-16

Active, closed

Acute Effects of Cold Exposure on Cognitive Function

NCT06654167Cognitive Function

Fudan University

Not applicable

Shanghai

2024-10-16

Recruiting

Acute Effects of Cold Exposure on Cardiovascular System

NCT06652425Cardiovascular System

Fudan University

Not applicable

Shanghai

2024-10-16

Recruiting

DEB-TACE Prior to Liver Transplantation in the Treatment of HCC

NCT06353126Liver Cancer

RenJi Hospital

Phase 4

Shanghai

2024-10-16

Recruiting

Effects of High-Intensity Interval Training on Bone Health in Hong Kong Older Women

NCT06888544Osteopenia

Hong Kong Baptist University

Not applicable

China

2024-10-16

Active, closed

Adebrelimab Combined With Irinotecan Liposomal (II), Oxaliplatin, and 5-FU/LV Conversion Therapy for Locally Advanced Pancreatic Cancer

NCT06766019Pancreatic Cancer

DrugAdebrelimab

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2024-10-16

Not yet open

An IIT Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of a Single Intrathecal Injection of SNUG01 in Patients with Amyotrophic Lateral Sclerosis

NCT06645197Amyotrophic Lateral Sclerosis (ALS)

DrugSNUG01

Peking University Third Hospital

Early Phase 1

Beijing, Fujian, Nanjing, Chengdu, Hangzhou

2024-10-16

Recruiting

Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency

NCT07115082Premature Ovarian Insufficiency

Yan Hongli

Phase 1/2

Shanghai

2024-10-15

Recruiting

The Value of 68Ga-grazytracer PET in Monitoring Responses to Immunotherapy of Advanced Soft Tissue Sarcomas

NCT06644287Advanced Soft Tissue Sarcomas

Ruijin Hospital

Observational

Shanghai

2024-10-15

Active, closed

MRD in PAAD Adjuvant Therapy

NCT06867146The Role of Molecular Residual Disease in the Treatment Strategy and Prognosis Prediction of Pancreatic Cancer Patients Undergoing Adjuvant Therapy, Molecular Residual Disease, Pancreatic Cancer, Adjuvant Therapy

Peking Union Medical College Hospital

Not applicable

Beijing

2024-10-15

Recruiting

Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

NCT06241482Neurocritical Care, Traumatic Brain Injury, Cerebrovascular Disease, Moderate or Severe Coma

Shanghai 6th People's Hospital

Not applicable

Shanghai

2024-10-15

Not yet open

To Evaluate Efficacy and Safety of TopicalKX-826 Solution in Chinese Male Patients With Androgenetic Alopecia

NCT06622824Androgenetic Alopecia (AGA)

Suzhou Kintor Pharmaceutical Inc,

Phase 2/3

756

Beijing

2024-10-15

Recruiting

Stereotactic Body Radiotherapy Followed by Tislelizumab Plus Platinum-based Chemotherapy Versus Tislelizumab Plus Platinum-based Chemotherapy as Neoadjuvant Therapy in Patients With Resectable Stage Ⅱ-Ⅲ Non-small Cell Lung Cancer: A Phase Ⅲ, Randomized, Multicenter, Prospective Study

NCT06598527Lung Cancer (NSCLC)

DrugTislelizumab

Yang Hong

Phase 3

360

Guangzhou

2024-10-15

Recruiting

Efficacy of Self-expandable and Balloon-expandable Valves in Patients With Ascending Aortic Dilation

NCT06743568Aortic Stenosis, Ascending Aortic Dilatation

China National Center for Cardiovascular Diseases

Not applicable

100

Beijing, Shenzhen, Kunming

2024-10-15

Recruiting

Anti-Mesothelin CAR-T Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

NCT07010523Mesothelin-positive Advanced Malignant Solid Tumors

DrugsFludarabine·Cyclophosphamide

First Affiliated Hospital of Zhejiang University

Not applicable

Hangzhou

2024-10-15

By invitation

A Phase I/II Clinical Study to Evaluate the Safety and Efficacy of Oral Teslanbaicin in Patients With Radiation Proctitis

NCT06974123Safety

The First Affiliated Hospital of Xinxiang Medical College

Phase 1/2

Xinxiang

2024-10-15

By invitation

LORLATINIB-related HYPERLIPIDEMIA in ALK+ Non-Small Cell Lung Cancer

NCT06876675Non-Small Cell Lung Cancer, Hyperlipidemia

DrugLorlatinib

Peking University Third Hospital

Observational

167

Beijing

2024-10-15

By invitation

Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Colorectal Cancer Surgery

NCT06636864Laparoscopic Colorectal Cancer Surgery

Sun Yat-sen University

Not applicable

252

Guangzhou

2024-10-15

Recruiting

HDAC Inhibitor Combination With Chemoimmunotherapy in the Neoadjuvant Treatment of pMMR Locally Advanced Colon Cancer

NCT06709885Colon Adenocarcinoma

DrugsCapeox·Chidamide·Tislelizumab

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Phase 2

100

Chongqing

2024-10-15

Not yet open

Preoperative Risk Evaluation and Per ERAS Intervention in the Chinese Elderly Patients Underwent Spinal Fusion Surgery

NCT06607081Degenerative Spinal Disease, Elderly Patients, Spinal Fusion Acquired

Xijing Hospital

Not applicable

5,000

Xi'an

2024-10-15

Active, closed

Daratumumab Combined With Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis With Translocation (11;14)

NCT06629818Light Chain (AL) Amyloidosis

DrugsDaratumumab·Venetoclax·Dexamethasone

Peking Union Medical College Hospital

Phase 2

Beijing

2024-10-15

Recruiting

Venous Congestion and Cardiac Surgery-Associated Acute Kidney Injury

NCT07232277Intraoperative, Venous Congestion, Cardiac Surgery-associated Acute Kidney Injury

Zhuan Zhang

Observational

114

Yangzhou

2024-10-15

Recruiting

A Cohort Study of Disease Prediction Model for High-risk Population With Bipolar Disorder

NCT07031661High-risk, Bipolar Disorder, Atypical Depression

Shanghai Mental Health Center

Observational

1,200

Shanghai

2024-10-15

Recruiting

Study of IBI363 in Patients with Advanced First-line Gastric Cancer

NCT06610799IBI363 + Chemotherapy

DrugLenvatinib

Xiangdong Cheng

Phase 1

Hangzhou

2024-10-15

Recruiting

Acupuncture for ADHD: Acupoint Data Mining, Clinical Effectiveness, and Interviews to Explore Treatment Outcomes.

NCT06860763Acupuncture, ADHD - Attention Deficit Disorder With Hyperactivity, Children, Interview

The Third Affiliated Hospital of Beijing University of Chinese Medicine

Not applicable

120

Beijing

2024-10-15

Recruiting

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT06632444Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver Fibrosis

Boehringer Ingelheim

Phase 3

1,800

Beijing, Changchun, Changsha, Changzhou Shi, Chengdu, Chongqing, Foshan, Fuzhou

2024-10-14

Active, closed

Combination of Vebreltinib and Osimertinib in Patients with EGFR 21 L858R Mutation Advanced NSCLC

NCT06827145Non-Small-Cell Lung Cancer

DrugsBozitinib·Vebreltinib·Osimertinib

National Cancer Center, China

Phase 2

Beijing

2024-10-14

Recruiting

A Clinical Study of [225Ac]Ac-FAPI-XT(XT117) Injection in Patients With Advanced Solid Tumors

NCT07135128Advanced Solid Tumor

Xiaorong Sun

Phase 1

Jinan

2024-10-14

Recruiting

A Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of [225Ac]Ac-PSMA-XT Injection in Patients With Metastatic Castration-resistant Prostate Cancer

NCT07135102Metastatic Castration-Resistant Prostate Cancer Patients

Xiaorong Sun

Phase 1

Jinan

2024-10-14

Recruiting

A Phase Ib Study of GC101 in NSCLC

NCT06473961Non Small Cell Lung Cancer Metastatic, Non Small Cell Lung Cancer

DrugAutologous Tumor Infiltrating Lymphocytes

Shanghai Juncell Therapeutics

Phase 1

Shanghai

2024-10-14

Recruiting

Exploratory Platform Research on Precision Therapy of Advanced Pancreatic Cancer

NCT06547736Pancreatic Cancer

DrugsSHR-A1904·HRS-4642·SHR-A2102·Trastuzumab Rezetecan

Fudan University

Phase 2

160

Shanghai

2024-10-14

Recruiting

Intelligent Segmentation Algorithm of Ultrasonic Image

NCT06646679Segmentation

Tongji Hospital

Observational

5,000

Wuhan

2024-10-14

Recruiting

Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin

NCT06698965Lung Cancer, Small Cell

DrugsTrilaciclib·Envafolimab

Shanghai Chest Hospital

Phase 2

Shanghai

2024-10-13

Active, closed

Phase I Clinical Trial of Quadrivalent Influenza Virus Split Vaccine

NCT06622590Influenza, Human, Influenza a, Influenza Type B, Influenza Viral Infections

Institute of Medical Biology, Chinese Academy of Medical Sciences

Phase 1

180

Nanning

2024-10-13

Recruiting

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients

NCT06418659Advanced Hepatocellular Carcinoma

Shanghai Changzheng Hospital

Early Phase 1

Shanghai

2024-10-12

Recruiting

Fecal Microbiota Transplantation (FMT) in Patients With Moderate to Severe Acute Pancreatitis

NCT07153809Acute Pancreatitis, Severe Acute Pancreatitis

Changhai Hospital

Not applicable

Shanghai

2024-10-12

Recruiting

Profile and Regulatory Network of Exercise in Improving Metabolic Phenotypes of Patients With Prediabetes

NCT06633575Prediabetes

Shanghai Zhongshan Hospital

Not applicable

Shanghai

2024-10-12

Active, closed

A Clinical Trial of TQB2102 for Injection in the Treatment of HER2 Low-Expressing Recurrent/Metastatic Breast Cancer

NCT06561607Breast Cancer

DrugTQB2102

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 3

542

Bengbu, Hefei, Beijing, Quanzhou, Zhangzhou, Lanzhou, Wuwei, Guangzhou

2024-10-11

Recruiting

MRI Performance and Risk Factors in Bilateral Vestibular Hypofunction

NCT07709143Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy, Presbyvestibulopathy

Shanghai 6th People's Hospital

Observational

120

Shanghai

2024-10-11

Recruiting

Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

NCT06581432Solid Tumours

DrugZongertinib

Boehringer Ingelheim

Phase 2

588

Beijing, Changsha, Hangzhou, Hefei, Nanchang, Nanjing, Shanghai, Wuhan

2024-10-11

Active, closed

Immune Cell Subsets in SLE Patients Treated with Telitacicept

NCT06677801Systemic Lupus Erythematosus (SLE)

DrugTelitacicept

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 4

Hangzhou

2024-10-11

Recruiting

Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery

NCT06778811Sleep Wake Disorders, Esketamine and the Quality of Recovery, Dexmedetomidine

Nanjing First Hospital, Nanjing Medical University

Phase 4

180

Nanjing

2024-10-11

Active, closed

3-Dimensional Mapping System: The PULSTAR II Study

NCT07586176Atrial Fibrillation (Paroxysmal), Paroxysmal AF, Pulsed Field Ablation

Shanghai Shangyang Medical Technology Co., Ltd.

Not applicable

152

Chengdu

2024-10-10

Recruiting

Coronary CT-Derived FFR-Guided Strategy Versus Medical Therapy

NCT05824520Coronary Artery Disease, Myocardial Ischaemia

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

1,066

Hangzhou

2024-10-10

Active, closed

Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis

NCT06615726Ischemic Stroke, Transient Ischemic Attack

Capital Medical University

Phase 3

1,300

Fuyang, Huainan, Suzhou, Wuhu, Beijing, Chongqing, Zhangzhou, Foshan

2024-10-10

Active, closed

CAPOX Plus Sintilimab and Bevacizumab Biosimilar (IBI305) for Neoadjuvant Treatment of Locally Advanced Gastric Cancer

NCT06667050Gastric Adenocarcinoma

DrugSintilimab and bevacizumab

West China Hospital

Phase 2

Chengdu

2024-10-10

Recruiting

ZR-MTX for PIOL Phase II Trial

NCT06973811Primary Intraocular Lymphoma

DrugsZanubrutinib·Methotrexate·Rituximab

Peking Union Medical College Hospital

Phase 2

Beijing

2024-10-10

Recruiting

Hypofractionated Postoperative Regional Nodal Irradiation for Patients With Intermediate-risk Breast Cancer

NCT06757621Breast Carcinoma

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 3

3,142

Beijing

2024-10-10

Recruiting

Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma

NCT06348264Salivary Gland Neoplasm Duct

DrugsLeuprolide Acetate·Rezvilutamide

Peking University First Hospital

Phase 2

Beijing

2024-10-10

Recruiting

A Prospective, Single-arm Clinical Study on the Safety and Efficacy of Ivoximab Combined With Temozolomide in the Treatment of Relapsed/Refractory Glioma

NCT07599371Relapsed/Refractory Glioma

DrugTemozolomide

The First Affiliated Hospital of Zhengzhou University

Phase 1/2

Zhengzhou

2024-10-10

By invitation

Clinical Study on the Combination of Xiaoyu Zhitong Formula and Lymphatic Drainage Technique to Improve the Symptoms of Knee Pain and Swelling in Cold Dampness Obstruction Type

NCT06911437Knee Osteoarthritis (OA)

tang jie

Observational

100

Beijing

2024-10-10

Recruiting

Virtual Ileostomy Versus Diverting Ileostomy in Patients Undergoing Total Mesorectal Excision

NCT06633133Rectal Cancer

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Not applicable

620

Chongqing

2024-10-10

Active, closed

The Impact of Low-Dose Esketamine Combined With Ciprofol on the Quality of Early Postoperative Recovery Among Elderly Patients Undergoing Painless Gastroscopy

NCT06617039Quality of Postoperative Recovery

DrugCiprofol

Northern Jiangsu People's Hospital

Not applicable

376

Yangzhou

2024-10-10

Recruiting

Short-Term Nutritional Enhancement Combined With Health Education in Postoperative Colorectal Cancer Patients: A Randomized Controlled Trial

NCT07087561Colorectal Cancer (Diagnosis), Malnutrition or Risk of Malnutrition

Xiaoqin Luo

Not applicable

360

Xi'an

2024-10-10

Recruiting

Ultra-Hypofractionated vs. Moderately Hypofractionated Proton Therapy for Early Breast Cancer After Lumpectomy

NCT07135661Breast Cancer, Proton Therapy

Shanghai Proton and Heavy Ion Center

Not applicable

312

Shanghai

2024-10-10

Recruiting

A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC.

NCT06371274Triple-negative Breast Cancer

DrugsATRA·Toripalimab

First Affiliated Hospital of Zhejiang University

Not applicable

Hangzhou

2024-10-10

Recruiting

Investigation of Cardiac Function Following Low-Intensity Ultrasound Intervention

NCT06567106Cardiac Function

ShanghaiTech University

Not applicable

Shanghai

2024-10-10

Recruiting

A Randomized Crossover Study on Diverse Training Methods to Enhance University Athletes' Performance and Health

NCT06546605Athletic Performance, Plyometric Exercise, Healthy

University of Macau

Not applicable

120

2024-10-10

Recruiting

A Study of IMC-002 for the Treatment of Active Systemic Lupus Erythematosus

NCT06535412Systemic Lupus Erythematosus

DrugIMC-002

ImmuneCare Biopharmaceuticals (Shanghai) Co., Ltd.

Phase 1/2

218

Beijing

2024-10-10

Recruiting

Adebrelimab Plus Apatinib and Etoposide for the Treatment of HER2-Negative Breast Cancer Brain Metastasis

NCT06418594HER2-negative Breast Cancer Brain Metastases

DrugsApatinib·Adebrelimab·Etoposide

Beijing 302 Hospital

Phase 2

Beijing

2024-10-10

Recruiting

Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB41 in Adult Patients with Advanced Malignant Solid Tumours.

NCT06600022Advanced Malignant Solid Tumours

DrugSCTB41

Sinocelltech Ltd.

Phase 1/2

441

Guangzhou

2024-10-10

Recruiting

Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Diabetic Macular Edema

NCT07515079Diabetic Macular Edema (DME)

DrugLucentis

Bio-Thera Solutions

Phase 3

406

Beijing, Chongqing, Lanzhou, Guangzhou, Shantou, Shenzhen, Nanning, Zunyi

2024-10-09

Recruiting

Smoking Cessation Program With CBT and Mindfulness Audio Support: A Randomized Controlled Trial

NCT06901713Smoking Cessation; Tobacco Dependence

Sir Run Run Shaw Hospital

Not applicable

2,000

Hangzhou

2024-10-09

Active, closed

Neoadjuvant Short-Course Radiotherapy Followed by CAPOX Plus PD-1 Antibody and IL-2 in Locally Advanced Rectal Cancer (PRIDE01)

NCT06577194Rectal Cancer, Advanced Solid Tumor

DrugsAldesleukin·Folfox·Sintilimab

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2024-10-09

By invitation

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SSS39 Injection in Healthy Chinese Subjects

NCT07057726Safety and Tolerability in Healthy Volunteers

Shenyang Sunshine Pharmaceutical Co., LTD.

Phase 1

Beijing

2024-10-09

Active, closed

LuX-Valve Plus System for Severe or Greater Tricuspid Regurgitation

NCT07705594Tricuspid Regurgitation (TR)

Jenscare Scientific

Not applicable

126

Shanghai

2024-10-09

Not yet open

Allogeneic Anti-BCMA/GPRC5D Bispecific CAR-NK Cells (ACT-001) in Patients With Relapsed or Refractorymultiple Myeloma

NCT06594211Multiple Myeloma

RenJi Hospital

Not applicable

Shanghai

2024-10-09

Recruiting

A Bioequivalence Study of PP3M in Patients With Schizophrenia

NCT07493551Schizophrenia

DrugPaliperidone Palmitate

CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Not applicable

260

Beijing

2024-10-09

Active, closed

Identify Effective Doses of LY01021 in Controlled Ovarian Hyperstimulation (COH) for Female Subjects Undergoing Assisted Reproductive Technology (ART)

NCT07236476Assisted Reproduction

Luye Pharma Group Ltd.

Phase 2

Beijing

2024-10-09

Recruiting

Establishment of Multiparametric Prediction Models for Moderate to SevereThyroid Associated Ophthalmopathy

NCT06590220Thyroid Associated Ophthalmopathy

Shanghai Changzheng Hospital

Observational

150

Shanghai

2024-10-09

Recruiting

Neoadjuvant Chemotherapy Combined With Toripalimab for TNBC (NEOTORCH-BREAST02)

NCT06682195TNBC, Triple Negative Breast Cancer

DrugToripalimab

First Affiliated Hospital of Zhejiang University

Phase 2

Nanchang, Hangzhou, Harbin, Hefei, Jinhua, Nantong, Shanghai, Shanxi

2024-10-09

Recruiting

QL1706 Plus Chemotherapy +/- Bevacizumab in 1L Treatment of R/mTNBC

NCT06786026TNBC, Triple Negative Breast Cancer

DrugsNab-paclitaxel·Lenvatinib·Bevacizumab

Fudan University

Phase 2

Shanghai

2024-10-09

By invitation

Application of Generative Artificial Intelligence in Perioperative Personalized Rehabilitation for Older Adults With Lung Cancer

NCT07915193Lung Neoplasms

Peking University Cancer Hospital & Institute

Not applicable

150

Beijing

2024-10-09

Active, closed

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

NCT06470048Diffuse Cutaneous Systemic Sclerosis

DrugIanalumab

Novartis Pharmaceuticals

Phase 2

201

Nanning, Zhengzhou, Chengdu, Ningbo, Beijing, Tianjin

2024-10-09

Recruiting

Study of LM-299 in Subjects Advanced Malignant Tumors

NCT06650566Malignant Tumors

DrugMK-2010

LaNova Medicines Limited

Phase 1/2

108

Xinxiang, Liaocheng, Zibo, Shanghai

2024-10-09

Recruiting

JY231 Injection for the Treatment of Active Systemic Lupus Erythematosus (SLE)

NCT06675422Systemic Lupus Erythematosus (SLE)

DrugJY231

920th Hospital of Joint Logistics Support Force of People's Liberation Army of China

Phase 1/2

Kunming

2024-10-09

Recruiting

A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma

NCT06367075Advanced Soft-tissue Sarcoma

DrugsAdriamycin·Cadonilimab·Doxorubicin

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 2

Wuhan

2024-10-09

Recruiting

Effects of Different Pressure Garments on Upper Extremity Sensorimotor Functions and Quality of Life After Stroke

NCT06587308Cerebral Vascular Accident (CVA)/Stroke

National University of Malaysia

Not applicable

165

Weifang

2024-10-08

Recruiting

Two Types of Single-use Flexible Ureteroscopies for the Treatment of Upper Urinary Tract Stones in Children

NCT06628765Urinary Stone

The Children's Hospital of Zhejiang University School of Medicine

Not applicable

Hangzhou

2024-10-08

Recruiting

The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation

NCT06561880FLT3 Gene Mutation, AML

DrugsAzacitadine·Gilteritinib·Cytarabine·Venetoclax

Institute of Hematology & Blood Diseases Hospital, China

Phase 1/2

Tianjin

2024-10-08

Active, closed

Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR + / HER2- Breast Cancer

NCT06599216Breast Cancer, HR+/HER2- Breast Cancer

DrugAdebrelimab

Harbin Medical University

Phase 2

Harbin

2024-10-08

Active, closed

An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE).

NCT06335979Systemic Lupus Erythematosus, SLE

DrugPIT565

Novartis Pharmaceuticals

Phase 1

Beijing

2024-10-08

Recruiting

Comparison of 5.0T and 3.0T Biparametric Magnetic Resonance Imaging in the Diagnosis of Prostate Cancer

NCT06612047Prostate Cancer

Anhui Provincial Hospital

Observational

150

Hefei

2024-10-08

Recruiting

TIPS Plus Half-dose Donafenib in AHCC with PVTT-associated Portal Hypertension

NCT06646198Hepatocellular Carcinoma with PVTT

DrugDonafenib

Fei Gao

Phase 2

Guangzhou

2024-10-08

Recruiting

Electroacupuncture Combined With Self-administered Acupressure for the Prevention of Capecitabine-Associated Hand-Foot Syndrome

NCT06602167Capecitabine, Hand-foot Syndrome, Electroacupuncture, Self-administered Acupressure

Affiliated Hospital of Qinghai University

Not applicable

220

Xining

2024-10-08

Active, closed

To Evaluate the Phase III Clinical Trial of TQH2722 Injection in the Treatment of Moderate to Severe Atopic Dermatitis

NCT06552520Atopic Dermatitis

DrugTQH2722

Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.

Phase 3

500

Bengbu, Tongling, Wuhu, Beijing, Chongqing, Xiamen, Guangzhou, Shenzhen

2024-10-08

By invitation

CNCMT：a Multi-center, Prospective, Single-arm Study

NCT06714084Locally Advanced Cervical Cancer, PD1, CTLA4

Hubei Cancer Hospital

Not applicable

Wuhan

2024-10-08

Active, closed

Endocrine and Exocrine Secretory Function Alterations After Moderately Severe and Severe Acute Pancreatitis

NCT06590935Acute Pancreatitis (AP), Diabetes Mellitus

Shanghai Changzheng Hospital

Observational

120

Shanghai

2024-10-08

By invitation

The Effects and Mechanism of Parent Intervention for Autism Sprectrum Disorder

NCT07393893Autism Spectrum Disorder

University of Electronic Science and Technology of China

Not applicable

Chengdu

2024-10-08

Recruiting

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

NCT06561386Non-small Cell Lung Cancer

DrugsRelatlimab·Pemetrexed·Nivolumab·Cisplatin

Bristol-Myers Squibb

Phase 3

1,000

Hefei, Beijing, Chongqing, Wanzhou, Fuzhou, Guangzhou, Huizhou, Liuzhou

2024-10-07

Recruiting

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

NCT06598306Extensive Stage Small Cell Lung Cancer

DrugTarlatamab

Amgen

Phase 1

220

Changchun, Shanghai

2024-10-07

Recruiting

AI-Assisted Non-Contrast CT for Multi-Cancer Screening

NCT06632886Lung Cancers, Liver Cancer, Gastric Cancers, Colorectal, Cancer

Guo ShiWei

Not applicable

1,000,000

Shanghai

2024-10-07

Recruiting

TEAS for Gastrectomy Recovery

NCT07898293Gastric Cancer (GC), Stomach Neoplasms

The Affiliated Hospital of Qingdao University

Not applicable

104

Qingdao, Rizhao, Weifang, Yantai

2024-10-07

Recruiting

Correlation Studies on Human Body Composition Based on Bioequivalence or Pharmacokinetic Trials

NCT07611929Healhty

Second Affiliated Hospital of Wenzhou Medical University

Observational

3,000

Wenzhou

2024-10-05

Recruiting

A Trial of SHR-7787 Injection in Patients With Advanced Solid Tumors

NCT06605222Advanced Solid Tumors

DrugSHR-7787

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 1/2

201

Shanghai

2024-10-04

Recruiting

Ablation of Pulmonary Oligometastasis Combined With System for Advanced Hepatocellular Carcinoma

NCT06644430Advanced Hepatocellular Carcinoma, Lung Cancer, Oligometastasis, Ablation

Sun Yat-sen University

Observational

470

Beijing

2024-10-04

Active, closed

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT06417814Metastatic Non-small Cell Lung Cancer

DrugsTagrisso·Dato-DXd·Osimertinib·Pemetrexed

AstraZeneca

Phase 3

768

Baoding, Beijing, Bengbu, Changchun, Changsha, Chengdu, Deyang, Ganzhou

2024-10-04

Recruiting

ARTEMIS-102: HS-20093 Combinations in Patients with Advanced Metastatic Colorectal Cancer

NCT06825624Metastatic Colorectal Cancer (CRC)

DrugsRis-Rez·Leucovorin·Adrucil·Capecitabine

Hansoh BioMedical R&D Company

Phase 1

560

Hangzhou

2024-10-03

Recruiting

A Study of BG-C477 in Participants With Advanced Solid Tumors

NCT06596473Advanced Solid Tumors

DrugTislelizumab

BeOne Medicines

Phase 1

310

Beijing, Chongqing, Fuzhou, Guangzhou, Nanning, Harbin, Jiamusi, Zhengzhou

2024-10-03

Recruiting

Allogeneic UCB-derived, Dual-targeting BCMA/CD19 CAR-T for Relapsed/Refractory Multiple Myeloma

NCT07139509Relapsed/Refractory Multiple Myeloma(MM)

Xi'an No.3 Hospital

Phase 1

Xi’an

2024-10-03

Recruiting

Extending the Time Window for Intravenous Tenecteplase in Patients With Distal Medium Vessel Occlusions Stroke

NCT06559436Acute Ischemic Stroke

The First Affiliated Hospital of University of Science and Technology of China

Not applicable

560

Hefei

2024-10-02

Active, closed

Clinical Safety and Efficacy of Fecal Microbiota Transplantation (FMT) in the Treatment of Alzheimer's Disease

NCT06920212Fecal Microbiota Transplantation

Shanghai 10th People's Hospital

Not applicable

Shanghai

2024-10-01

Active, closed

Clinical and Mechanistic Research on Autogenous Arteriovenous Fistula in Hemodialysis Patients

NCT07058441Arteriovenous Fistula Maturation Failure in End-stage Renal Disease

Ai Peng

Observational

100

Shanghai

2024-10-01

Recruiting

VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS

NCT06471946Higher-risk Myelodysplastic Syndromes

DrugVenetoclax

Navy General Hospital, Beijing

Phase 1/2

Beijing

2024-10-01

Recruiting

Bridging Allogeneic Hematopoietic Stem Cell Transplantation or Not After CD19 CAR - T (S1904) Cell Therapy for r/r B-cell Acute Lymphoblastic Leukemia

NCT06581081Relapsed Adult ALL, B-cell Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic Leukemia, Relapsed Pediatric ALL

Peking University People's Hospital

Not applicable

130

Beijing

2024-10-01

Recruiting

HAIC Compared With TACE in Huge Hepatocellular Carcinoma

NCT06641713Hepatocellular Carcinoma, Hepatic Chemotherapy, Liver Cancer

Sun Yat-sen University

Observational

664

Beijing

2024-10-01

Recruiting

dTACE-HAIC Combined With Bevacizumab and Atezolizumab for Huge Hepatocellular Carcinoma

NCT06609863Advanced Hepatocellular Carcinoma, Atezolizumab, Bevacizumab, Chemotherapy

Sun Yat-sen University

Not applicable

Beijing

2024-10-01

Recruiting

CD19/CD22 CAR-T Cell Therapy in MRD-Positive B-lineage Acute Lymphoblastic Leukemia in Children.

NCT06752785Acute Lymphoblastic Leukemia

Guangzhou Women and Children's Medical Center

Phase 1

Guangzhou

2024-10-01

Recruiting

Thumbtack Needle in the Treatment of NVP

NCT06566274Nausea and Vomiting in Pregnancy (NVP)

Dongmei Huang

Not applicable

320

Jingzhou, Nanzhang Chengguanzhen, Qianjiang, Shiyan, Suizhou, Wuhan, Xiangyang, Xiaogan

2024-10-01

Recruiting

High-dose Furmonertinib or Combined With Chemotherapy in EGFR-mutant Advanced NSCLC After Disease Progression on Third-generation EGFR-TKI

NCT06652048Non-Small Cell Lung Cancer

DrugFurmonertinib

Jialei Wang

Phase 2

Shanghai

2024-10-01

Recruiting

Effect of Hypophosphatemia on Neuro-excursion Efficiency During Mechanical Ventilator Weaning

NCT06754670Mechanical Ventilation, Weaning Failure, Hypophosphatemia

Peking Union Medical College

Observational

Beijing

2024-10-01

Recruiting

The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis

NCT06898723Septic Cardiomyopathy, Septic Shock

DrugShenfu

First Affiliated Hospital of Wannan Medical College

Phase 4

440

Wuhu

2024-10-01

Recruiting

Assessment and Management of Multiple Drug Use in Elderly Chronic Disease Patients

NCT07180368Coronary Artery Disease, Diabete Mellitus, Chronic Kidney Disease, Hypertension

Xijing Hospital

Observational

2,000

Xi'an

2024-10-01

Recruiting

Evaluation of Recombinant Humanized Anti-CD25 Monoclonal Antibody for Preventing Graft-versus-host Disease After Haploidentical/matched Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients with Transfusion-dependent Thalassemia

NCT06657391Transfusion Dependent Thalassemia

Rongrong Liu

Phase 2

396

Maoming, Liuzhou, Nanning, Yulin, Haikou

2024-10-01

Recruiting

Wearable Device-Based Analysis of the Relationship Between Sleep Patterns and Clinical Prognosis in Patients With Traumatic Brain Injury

NCT06790979Traumatic Brain Injury (TBI); Concussion, Initial Encounter

General Hospital of Ningxia Medical University

Observational

Yinchuan

2024-10-01

Active, closed

TS Triage of HR-HPV Positive Population and Its Accuracy Study

NCT07777094Cervical Precancerous Lesions, Cervical Cancer

Affiliated Hospital of Nantong University

Observational

300

Nantong

2024-10-01

Recruiting

AI-Empowered Fundus Platform

NCT07424755High Myopia

Shanghai 10th People's Hospital

Observational

1,000

Shanghai

2024-10-01

Active, closed

Metabolomics Predictors for Metabolic Disease Remission After Metabolic Syndrome Surgery.

NCT06645730Metabolic Syndrome

First Affiliated Hospital of Chongqing Medical University

Observational

150

Chongqing

2024-10-01

Recruiting

Organoid-based Functional Precision Therapy for Advanced Breast Cancer

NCT06102824HER2-negative Breast Cancer, Advanced Breast Cancer

DrugsAnthracycline·Utidelone·Pegylated liposomal doxorubicin·Eribulin

Guangdong Provincial People's Hospital

Phase 2

252

Guangzhou

2024-10-01

Recruiting

Multimodalomics-based Construction of Spatiotemporal Characteristics of Dynamic Liver Cancer Microenvironment to Characterize the Clinical Application of Immune Mechanisms in Liver Cancer

NCT07838415Hepatocellular Carcinoma (HCC), Treatment Response

Tongji Hospital

Observational

400

Wuhan

2024-10-01

Recruiting

Multitarget Stereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome

NCT06889480Tourette Syndrome, Deep Brain Stimulation

Beijing Tiantan Hospital

Not applicable

Beijing

2024-10-01

Active, closed

Effects of an Individual and Family Self-Management of Fall Prevention Program on Balance Ability and Fall-related Self-efficacy Among Chinese Post-Stroke Individuals

NCT06577662Stroke, Ischemic, Self Efficacy, Fall

Chiang Mai University

Not applicable

Guiyang

2024-10-01

Recruiting

Application of Phototherapeutic Keratectomy Mode to Mark the Axis of Astigmatism

NCT06694051Astigmatism

Tianjin Eye Hospital

Not applicable

100

Tianjin

2024-10-01

By invitation

Influencing Factors and Outcomes of DCB Angioplasty

NCT06620458Coronary Artery Disease

Henan Institute of Cardiovascular Epidemiology

Observational

5,000

Zhengzhou

2024-10-01

By invitation

Application of PDCA Cycle in Tracheal Intubation Training for Emergency Medicine Residents

NCT07146984Tracheal Intubation, Medical Education

Guangzhou Panyu Central Hospital

Observational

100

Guangzhou

2024-10-01

Active, closed

Impact of Environmental Factors and Metabolomics on Colorectal Cancer.

NCT06643429Colorectal Cancer, Metabolic Disease

Dong Peng

Observational

700

Chongqing

2024-10-01

Active, closed

Predictive Value of Air Pollution and Metabolomics for Gastric Cancer.

NCT06641700Gastric Cancers

Dong Peng

Observational

200

Chongqing

2024-10-01

Recruiting

Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Disease

NCT07022522Parkinson Disease, Deep Brain Stimulation

Beijing Tiantan Hospital

Not applicable

Beijing

2024-10-01

Recruiting

Treatment Strategy of Human Gamma Globulin on the Therapy for Intensively Ill Children With Inflammatory Storm

NCT04850456Critical Illness, Sepsis, Severe

Children's Hospital of Fudan University

Observational

200

Shanghai

2024-10-01

Recruiting

Application of Non-inductive Intelligent Physical Sign Monitoring Equipment Based on Flexible Electronic Devices in the Diagnosis and Treatment of Cardiovascular Diseases

NCT07466056Cardiovascular Disease

Beijing Anzhen Hospital

Observational

1,100

Beijing

2024-10-01

Not yet open

All-cause and Diseases-specific Mortality of High-risk HPV Infection

NCT06631495HPV Infection

Peking Union Medical College Hospital

Observational

100,000

Beijing

2024-10-01

Recruiting

Hypofractionated Radiotherapy for Thymic Epithelial Tumors

NCT06692062Thymoma and Thymic Carcinoma, Thymoma, Thymic Cancer, Thymic Epithelial Tumor

Rongrong Zhou

Not applicable

100

Changsha

2024-10-01

By invitation

Next-generation Sequencing Technology in the Clinical Application of Respiratory Specimens

NCT07191080Lung Infection

Bin Zhang

Observational

Nantong

2024-10-01

Active, closed

Study on the Relationship Between Indoor Environment, Use of Personal Disinfection Products, and Human Health

NCT06637826Healthy

National Natural Science Foundation of China

Early Phase 1

Shenzhen

2024-10-01

Recruiting

A Multicenter Study Evaluating the Diagnostic Value of 68Ga-MY6349 PET/CT for Prostate Cancer

NCT06696326Positron-Emission Tomography(PET), Prostate Cancer, Trophoblast Cell Surface Antigen 2

The First Affiliated Hospital of Xiamen University

Not applicable

100

Xiamen

2024-10-01

Recruiting

Clinical Application of PET Imaging Targeting MSLN in Malignant Tumors

NCT06843629Ovarian Cancer, Lung Adenocarcinoma, Pancreatic Cancer

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

100

Wuhan

2024-10-01

By invitation

Sonodynamic-Chemoradiotherapy Integration in Glioblastoma

NCT07130149Glioblastoma (GBM)

Yingjuan Zheng

Phase 2

230

Zhengzhou

2024-10-01

By invitation

The Effect of Physical Activity Level Evaluated by Wrist-wearable Devices on Cardiovascular Disease Risk and Other Outcomes in Peritoneal Dialysis Patients

NCT06697418Peritoneal Dialysis, Cardiovascular Diseases, Myocardial Infarct, Heart Failure

Ruijin Hospital

Observational

266

Shanghai

2024-10-01

Recruiting

Interventional Treatment of Chronic Tinnitus With Acoustic Stimulation

NCT07185061Chronic Tinnitus

The First Affiliated Hospital with Nanjing Medical University

Not applicable

200

Nanjing

2024-10-01

Recruiting

Azacytidine Plus CAOLD Regimen in Relapsed/Refractory Peripheral T-Cell Lymphomas

NCT06176027Relapsed Peripheral T-Cell Lymphomas, Refractory Peripheral T-Cell Lymphomas

DrugAzacytidine

Navy General Hospital, Beijing

Phase 1/2

Beijing

2024-10-01

Recruiting

Brain Activation Pattern Caused by Immersive Virtual Reality Pathfinding Task in Stroke Patients: an FNIRS Study

NCT06703320Stroke, Cognitive Decline

Dingqun Bai

Observational

Chongqing

2024-10-01

Recruiting

Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia

NCT06734520Thalassemia Majors (Beta-Thalassemia Major), Haplo-identical Donors

Guangzhou Women and Children's Medical Center

Not applicable

Guangzhou

2024-10-01

By invitation

Retrospective Study on Leptomeningeal Metastasis of Solid Tumors

NCT06705049Leptomeningeal Metastasis

Shanghai Zhongshan Hospital

Observational

107

Shanghai

2024-10-01

Not yet open

SHR-1501 Combined With SHR-2005 for High-Risk Non-Muscle Invasive Bladder Cancer Which is Not Completely Resectable by TURBt

NCT06588179NMIBC

DrugsSHR-2005·SHR-1501

Fudan University

Phase 1/2

Shanghai

2024-10-01

Not yet open

Double Dose of Third-generation EGFR-TKI Plus Intrathecal Pemetrexed Versus Double Dose of Third-generation EGFR-TKI in Patients With LM Progression Following the Treatment of Routine Dose of Third-generation EGFR-TKI

NCT06441045Leptomeningeal Metastasis

DrugPemetrexed

Fujian Cancer Hospital

Phase 2

112

Fuzhou

2024-10-01

Recruiting

Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS

NCT06367218Video-assisted Thoracoscopic Lung Surgery；Anesthesia

Tongji Hospital

Not applicable

480

Wuhan

2024-10-01

By invitation

A Randomized Double-Blind Active-Controlled Crossover Trial of Respiratory-Gated Versus Non-Gated Transcutaneous Auricular Vagus Nerve Stimulation for the Treatment of Motor and Non-Motor Symptoms in Parkinson's Disease

NCT06642454Parkinson Disease, Apathy, Sleep Disorder, Motor Disorders

Anhui Medical University

Not applicable

Hefei

2024-10-01

Recruiting

PD-L1 Antibody + Bevacizumab With Hepatic Arterial Infusion Chemotherapy for Advanced HCC

NCT06742424Hepato Cellular Carcinoma (HCC)

DrugBevacizumab

West China Hospital

Phase 2

Chengdu

2024-10-01

Not yet open

Adebrelimab Combined with Non-platinum Chemotherapy and Fuzuloparib in Recurrent Platinum-resistant Ovarian Cancer

NCT06600841Platinum-resistant Ovarian Cancer (PROC), Immunotherapy

DrugImmunotherapy: Adebrelimab

Fujian Cancer Hospital

Phase 2

Fuzhou

2024-10-01

Recruiting

Phase II Clinical Study of Befotertinib in EGFR Non-classical Mutant NSCLC

NCT06863506NSCLC (Non-small Cell Lung Cancer)

DrugBefotertinib

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

Hangzhou

2024-10-01

Recruiting

Spatial Fragmentation Combined With Low-dose Radiotherapy for Immunotherapy Combined With Chemotherapy-resistant Locally Advanced or Advanced Non-small Cell Lung Cancer

NCT06775678Lung Cancers, Radiation Treatment for Tumors

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-10-01

By invitation

A Prospective Single-center Randomized Controlled Trial of Robotic Surgery With Transrectal Resection Specimens (NOSES-IV) and Traditional Assisted Robotic Surgery for the Treatment of High Rectal and Sigmoid Colon Cancer

NCT06906952Natural Orifice Specimen Extraction Surgery, Robotic Surgery, Short-term Outcomes

Nanchang University

Not applicable

100

Nanchang

2024-10-01

Not yet open

A Clinical Trial of Furmonertinib Combination Therapy As Neoadjuvant Treatment in Resectable EGFR-Mutated NSCLC

NCT06585644Lung Cancer (NSCLC)

DrugFurmonertinib

Shanghai Pulmonary Hospital, Shanghai, China

Phase 2

Shanghai

2024-10-01

Recruiting

Older People's Preventive Care Utilization

NCT05691790Health Communication

The University of Hong Kong

Not applicable

270

2024-10-01

Recruiting

Transaxillary TAVR With Solely Echocardiography Guidance

NCT07035847Aortic Stenosis

Chinese Academy of Medical Sciences, Fuwai Hospital

Not applicable

Beijing

2024-10-01

By invitation

Efficacy and Safety of Tofacitinib in Refractory Blau Syndrome

NCT06660329Blau Syndrome

Peking Union Medical College Hospital

Phase 4

Beijing

2024-10-01

Active, closed

Comparison of the Effect of Capsular Bend on the Rotational Stability Between Two Toric Intraocular Lenses

NCT06707740Cataract

Wenzhou Medical University

Observational

Wenzhou

2024-10-01

Recruiting

Risk Factors for Developing Peak Plantar Pressure During Walking in the Diabetic Patients

NCT07164495Diabete Type 2

China Medical University Hospital

Observational

120

2024-10-01

Not yet open

Exosome-based OCS Scores for Predicting Ovarian Cancer Recurrence

NCT06558019Ovarian Cancer

Lei Li

Observational

509

Beijing

2024-10-01

By invitation

A Study of the Mechanisms by Which Mood and Sleep Disorders Interact

NCT07495189Sleep Disorder Insomnia Chronic

Qilu Hospital of Shandong University

Observational

200

Jinan

2024-10-01

Recruiting

TIPS Combined With Lenvatinib and PD-1 Inhibitor for Advanced HCC With Main Trunk PVTT

NCT06622031Hepatocellular Carcinoma, Portal Vein Tumor Thrombus, Systemic Therapy

DrugLenvatinib

Sun Yat-sen University

Not applicable

Beijing

2024-10-01

By invitation

Study on The Sensitizing Effect of Sonodynamic Therapy on The Treatment of Brainstem Glioma With Radiotherapy and Chemotherapy and Survival Analysis

NCT06999148Glioma (Any Grade) in the Brain

DrugTemozolomide

Yingjuan Zheng

Phase 2

216

Zhengzhou

2024-10-01

Recruiting

A Research Protocol for Evaluating the Efficacy of Perfused Chemotherapeutic Agents for Bladder Cancer Based on Organoid Technology

NCT06662071Bladder Cancer

Qilu Hospital of Shandong University

Observational

293

Binzhou, Dezhou, Jinan, Jining, Liaocheng, Linyi, Qingdao, Taian

2024-10-01

Not yet open

Respiratory Disease Cohort Studies of Chinese Medicine for COPD(RESEARCH-COPD)

NCT06577701Chronic Obstructive Pulmoriary Disease (COPD), Preserved Ratio Impaired Spirometry (PRISM)

Henan University of Traditional Chinese Medicine

Observational

10,000

Zhengzhou

2024-10-01

Recruiting

The Comparison of TACE-Lenvatinib With TACE-Lenvatinib-ablation for Intermediate Recurrent Hepatocellular Carcinoma

NCT06609850Recurrent Hepatocellular Carcinoma, Lenvatinib, Local Therapy, Ablation

DrugLenvatinb

Sun Yat-sen University

Not applicable

116

Beijing

2024-10-01

Recruiting

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

NCT06675201Esophageal Squamous Cell Carcinoma (ESCC), Neoantigen-loaded Dendritic Cell Vaccine, Immune Checkpoint Inhibitors (ICIs)

Sichuan University

Phase 2

165

Chengdu

2024-10-01

Active, closed

ATTR-CM: A Multi-country, Non-interventional Disease Registry

NCT06651073Transthyretin Amyloid Cardiopathy

Pfizer

Observational

350

2024-10-01

Active, closed

Precision Regional Node Irradiation for Sentinel Node-positive Breast Cancer

NCT06583655Breast Cancer Invasive

Ruijin Hospital

Not applicable

205

Shanghai

2024-10-01

Recruiting

Donafenib as Adjuvant Therapy Following Ablation for Recurrent HCC

NCT06609876Hepatocellular Carcinoma, Microwave Ablation, Donafenib, Recurrent Tumor

DrugDonafenib

Sun Yat-sen University

Not applicable

108

Beijing

2024-10-01

Recruiting

Validation of High-Throughput Large-Format Tissue Preprocessing for Lung and Colorectal Cancer

NCT07239063CRC (Colorectal Cancer), Lung Cancer (Diagnosis)

Nanfang Hospital, Southern Medical University

Observational

1,000

Guangzhou

2024-10-01

Recruiting

Adebrelimab Neoadjuvant Treatment for Resectable ESCC: 2 vs 4 Cycles Study

NCT06663059Esophageal Cancer

DrugAdebrelimab

Tang-Du Hospital

Phase 2

Xi'an

2024-10-01

Recruiting

Efficacy and Safety of Hetrombopag in Preventing Chemotherapy-induced Thrombocytopenia in Gastrointestinal Tumors

NCT07492693Chemotherapy-induced Thrombocytopenia (CIT) in Patients With Gastrointestinal Tumors

DrugHetrombopag

Changhai Hospital

Phase 2

Shanghai

2024-10-01

By invitation

Facial Aesthetic Analysis Model Based on Clinical Cohort Phenotype to Explore 45° Facial Profile.

NCT06984666Malocclusion, Angle Class II, Malocclusion, Angle Class III

Linyu Xu

Not applicable

Fuzhou

2024-10-01

Not yet open

Clinical Study of Therapeutic Immunological Agent for EBV Lymphoproliferative Diseases

NCT06666153CAEBV (Chronic Active Epstein-Barr Virus Infection) Syndrome, PTLDs

West China Hospital

Phase 1

Chengdu

2024-10

Not yet open

Molecular Subtype-Guided R-CHOP-MTX±Zanubrutinib Treatment in Newly Diagnosed DLBCL Patients with Central Nervous System Involvement

NCT06594432Diffuse Large B Cell Lymphoma (DLBCL)

DrugR-Chop

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2024-10

Not yet open

Evaluating the Benefits of Personalized Traditional Chinese Medicine in Postoperative Treatment for Locally Advanced Colorectal Cancer

NCT06596343Locally Advanced Colorectal Cancer, Postoperative Adjuvant Therapy

Sir Run Run Shaw Hospital

Phase 2

Hangzhou

2024-10

Not yet open

A Clinical Trial Evaluating the Efficacy and Safety of Disitamab Vedotin Plus Tislelizumab Combined with Re-TURBT in the Treatment of HER-2-high Expression(2+-3+) Non-muscle Invasive Bladder Cancer At High-risk and Very High-risk.

NCT06630871NMIBC

DrugTislelizumab

Fujian Medical University Union Hospital

Phase 2

Fuzhou

2024-10

Not yet open

Adebrelimab Combined with Irinotecan Liposomes, 5-FU, CF ± Lenvatinib As First-line Treatment for Advanced ICC

NCT06648525Intrahepatic Cholangiocarcinoma (Icc)

DrugsIrinotecan liposomes·Calcium folinate·Adebrelimab·Adrucil

Harbin Medical University

Phase 2

Harbin

2024-10

Active, closed

A Study to Evaluate C-CAR031 in Glypican-3 (GPC3)+ Advanced/Recurrent Hepatocellular Carcinoma (HCC)

NCT06590246Hepatocellular Carcinoma

Shanghai AbelZeta Ltd.

Phase 1/2

121

Shanghai, Hanzhou

2024-09-30

Not yet open

CES and EGChatbot in Reducing Anxiety, Depression, Insomnia, and Mental Risk

NCT06493695Depression, Anxiety

China Medical University Hospital

Not applicable

180

2024-09-30

Not yet open

Efficacy of PD-1 Inhibitor Combination Therapy in Non-small Cell Lung Cancer Patients Who Have Not Achieved Major Pathologic Response After Neoadjuvant Immunotherapy: a Multicenter, Phase II Clinical Trial

NCT06620822Non Small Cell Lung Cancer

DrugsLM-108·Ipilimumab N01·Sintilimab·Lenvatinib

Shanghai Pulmonary Hospital, Shanghai, China

Phase 2

296

Shanghai

2024-09-30

Recruiting

Efficacy and Safety of Calculus Bovis Sativus (CBS) for Adult Encephalitis (CBSinEncephalitis)

NCT06584045Encephalitis, Encephalitis, Viral, Autoimmune Encephalitis Caused by N-Methyl D-Aspartate Receptor Antibody, Autoimmune Encephalitis

DrugCalculus bovis sativus

Tongji Hospital

Not applicable

250

Wuhan

2024-09-30

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site. Derived from ClinicalTrials.gov. Retrieved 7 November 2026. https://priyalifescience.com/clinical-trials-china?page=24

Query this register directly

GET /api/trials?country=cn&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,187 studies in total at the last sync on 07 Nov 2026, 03:17 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in China?

11,790 of the 19,187 studies in this register are recruiting new participants as of the 07 Nov 2026, 03:17 UTC sync. A further 3,998 have not yet opened recruitment, 2,715 are active but closed to new participants, and 684 are enrolling by invitation only. Eligibility for any study is decided by its study team.

→

Browse trials by condition

Breast Cancer (423) Advanced Solid Tumors (187) Colorectal Cancer (179) Gastric Cancer (175) Hepatocellular Carcinoma (154) Advanced Solid Tumor (153) Non-Small Cell Lung Cancer (145) Solid Tumor (142) Acute Ischemic Stroke (140) Lung Cancer (135) Non-small Cell Lung Cancer (132) Pancreatic Cancer (131) Multiple Myeloma (128) Coronary Artery Disease (122) Prostate Cancer (110)

→

Browse trials by site location

Beijing (5576) Shanghai (3879) Guangzhou (3345) Hangzhou (1819) Wuhan (1343) Chengdu (1307) Nanjing (1211) Changsha (1154) Chongqing (1078) Fuzhou (1040) Tianjin (934) Zhengzhou (931) Hefei (896) Jinan (783) Changchun (639)

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.