Clinical trial register · China

Clinical Trials in China

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 19187 matching records held by the registry are in this view. Synced 07 Nov 2026, 03:17 UTC

19187

Studies in scope

all four open statuses

11790

Recruiting now

open to new participants

2028

Lead sponsors

across recruiting studies

Top sites

Beijing 5576 Shanghai 3879 Guangzhou 3345 Hangzhou 1819 Wuhan 1343

Trials in this register

Status

Study

Lead sponsor

Phase

Enrol

Chinese sites

Start

Recruiting

A Study to Explore the Reasonable Dosage and Evaluate the Efficacy, Safety and Tolerability of HLX10 and HLX04 with or Without HLX53 in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients.

NCT06349980Carcinoma, Hepatocellular

DrugsHLX04·Serplulimab·Bevacizumab

Shanghai Henlius Biotech

Phase 2

117

Shanghai

2024-08-05

Active, closed

Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension

NCT06492291Hypercholesterolemia

DrugsEnlicitide Decanoate·Enlicitide

Merck Sharp & Dohme LLC

Phase 3

3,000

Beijing, Chongqing, Guangzhou, Huizhou, Shenzhen, Jingzhou, Wuhan, Changsha

2024-08-05

Recruiting

Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia

NCT06386302AML, Acute Myeloid Leukemia

DrugsChidamide·Azacitidine·Venetoclax

Institute of Hematology & Blood Diseases Hospital, China

Not applicable

184

Tianjin

2024-08-05

By invitation

2D Video Gait Analysis Platform Applying to AI Model for Adjustment of the Shoes' Sole

NCT07003087Gait Disorders

China Medical University Hospital

Observational

2024-08-05

Active, closed

Iptacopan in Patients With ANCA Associated Vasculitis

NCT06388941Anti-Neutrophil Cytoplasm Antibodies (ANCA) Associated Vasculitis

DrugsIptacopan·Rituximab

Novartis Pharmaceuticals

Phase 2

Shijiazhuang, Zhengzhou, Beijing

2024-08-05

Recruiting

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

NCT06428019Chronic Lymphocytic Leukemia

DrugsAcalabrutinib·Obinutuzumab·Venetoclax

AbbVie

Phase 3

170

2024-08-05

Recruiting

Trial of JYB1904 in Chronic Spontaneous Urticaria.

NCT06509334Chronic Spontaneous Urticaria

DrugsOzureprubart·Omalizumab

Jemincare

Phase 2

135

Beijing

2024-08-04

Recruiting

Identifying Local Field Potential Biomarkers for Obsessive-compulsive Disorder Treatment With Deep Brain Stimulation

NCT06542224Obsessive-Compulsive Disorder

West China Hospital

Not applicable

Chengdu, Zigong

2024-08-03

Recruiting

AI-powered Early Detection for Pancreatic Cancer Via Non-contrast CT in Opportunistic Screening Cohort

NCT06638866Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Pancreatic Intraepithelial Neoplasias, Intraductal Papillary Mucinous Neoplasm

Changhai Hospital

Observational

5,000

Shanghai, Jiaxing, Ningbo

2024-08-03

Recruiting

Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation

NCT06542094Major Depressive Disorder, Treatment Resistant Depression

West China Hospital

Not applicable

Chengdu

2024-08-03

Recruiting

A Phase Ib/II Study of Adebrelimab in Combination with Capecitabine and Oxaliplatin in Cancer

NCT06776770Gastric Cancer

DrugAdebrelimab

Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center

Phase 1/2

Shenzhen

2024-08-03

Recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Unresectable Locally Advanced or Recurrent Metastatic Triple-negative Breast Cancer

NCT06471205Triple-negative Breast Cancer

DrugIza-bren

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 2

Shanghai

2024-08-02

Recruiting

FAPI and FDG PET/MRI in Diagnosis and Therapy Prediction of Bladder Cancer

NCT06421142Urinary Bladder Neoplasms

First Affiliated Hospital of Fujian Medical University

Not applicable

Fuzhou

2024-08-02

Recruiting

A Study of BL-M14D1 in Patients With Locally Advanced or Metastatic Small Cell Lung Cancer, Neuroendocrine Tumors and Other Solid Tumors

NCT06505824Small Cell Lung Cancer, Neuroendocrine Tumors

DrugAtezolizumab

Biokin (Shanghai) Biopharmaceutical Co., Ltd.

Phase 1

115

Shanghai

2024-08-02

Active, closed

Study of CM310 in Adolescent Subjects With Atopic Dermatis

NCT06495229Atopic Dermatitis

DrugStapokibart

Keymed Biosciences Co.Ltd

Phase 3

180

Beijing

2024-08-02

Recruiting

A Study to Evaluate Features of KN069 in Participants With Obesity or Overweight

NCT06547775Overweight or Obesity

Suzhou Alphamab Co., Ltd.

Phase 1

Changsha

2024-08-02

Recruiting

POASAC Study (Preoperative Anemia Severity and Classification Study)

NCT06499974Anemia

Peking Union Medical College Hospital

Observational

1,000

Wuhu, Beijing, Zhangzhou, Zunyi, Chifeng, Hohhot

2024-08-02

Recruiting

A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma

NCT06371157Hepatocellular Carcinoma

DrugsCadonilimab·Lenvatinib

Akeso

Phase 3

469

Zhengzhou, Changsha, Nanjing, Hangzhou

2024-08-02

Recruiting

Concurrent Nab-paclitaxel with Intensity-modulated Radiation Therapy in Patients with Stage III-IVa Nasopharyngeal Carcinoma

NCT06611150Nasopharyngeal Carcinoma (NPC)

DrugNab-paclitaxel

Sun Yat-sen University

Phase 1

Guangzhou

2024-08-02

Recruiting

Clinical Study on the Effectiveness of Diverse Segments Defocus Optimization in Spectacle Lenses for Slowing Myopia Progression

NCT07323251Children With Myopia, Treatment, Multizone Lens Design for Myopic Defocus, Visual Quality

Beijing Tongren Hospital

Not applicable

120

Beijing

2024-08-02

Recruiting

Registry Study of Chinese Patients with Marginal Zone Lymphoma (MOTIVE)

NCT06534463Marginal Zone Lymphoma

Ruijin Hospital

Observational

500

Shanghai

2024-08-02

Recruiting

The Influence of Climate and Air Pollution on Physical Activity of Chinese People in Shenyang and Shenzhen

NCT07523659Physical Activity, Climate, Air Pollution

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Observational

124

Shenzhen, Shenyang

2024-08-01

Recruiting

Environmental Determinants of Type 1 Diabetes Risk

NCT07835724Type 1 Diabetes Mellitus (T1DM), Healthy Control, Relatives to/Carers of Patients

Second Xiangya Hospital of Central South University

Observational

11,240

Changsha

2024-08-01

Active, closed

An Observational Study of Subcutaneous Implantable Cardioverter Defibrillator in Patients with Hypertrophic Cardiomyopathy At High Risk of Sudden Cardiac Death

NCT06604169HCM - Hypertrophic Cardiomyopathy, S-ICD System (implantable Defibrillator)

China National Center for Cardiovascular Diseases

Observational

589

Beijing

2024-08-01

Recruiting

The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for the Trigeminal Neuralgia

NCT06472323Trigeminal Neuralgia, Idiopathic, PRP

Beijing Tiantan Hospital

Observational

270

Beijing

2024-08-01

Recruiting

Ablation of Oligometastasis Combined With Lenvatinib and PD-1 Inhibitor for Advanced Hepatocellular Carcinoma

NCT06550921Advanced Hepatocellular Carcinoma, Oligometastasis, Ablation, Anti-PD1 Antibody

Sun Yat-sen University

Not applicable

Beijing

2024-08-01

Recruiting

Efficacy and Safety Study of Ultra-early Mobile Stroke Unit Neuroprotection Combined With Revascularization for Acute Ischemic Stroke (EXCELLENT)

NCT07119021Ischemic Stroke

DrugEdaravone

Ruijun Ji

Phase 4

300

Beijing

2024-08-01

Recruiting

Primary Aldosteronism: Superselective Embolization vs. Laparoscopic Endocrine Curative Therapy

NCT06513585Primary Aldosteronism, Suprarenalectomy, Super Selective Adrenal Artery Embolization

Xinjiang Medical University

Not applicable

570

Ürümqi

2024-08-01

Active, closed

Dachengqi Decoction for Enhancing Early Gastrointestinal Recovery After Whipple Surgery

NCT06948474Whipple Operation

China-Japan Friendship Hospital

Not applicable

Beijing

2024-08-01

By invitation

The Impact of 3D Patch One-Suture Fixation vs No Fixation on Chronic Pain and Recurrence in Ⅲ Inguinal Hernia

NCT06879860Inguinal Hernia

Nanchong Central Hospital

Not applicable

150

Nanchong

2024-08-01

Recruiting

Clinical Study of a New Treatment Model for Elderly Lung Cancer Patients

NCT07632664Lung Neoplasm, Thoracic Surgical Procedures, Perioperative Care, Postoperative Rehabilitation

Peking University People's Hospital

Not applicable

1,000

Beijing

2024-08-01

Recruiting

A New Strategy for Preoperative Drainage of Resectable Pancreatic Head Cancer Combined Severe Obstructive Jaundice

NCT06541340Pancreatic Cancer, Obstructive Jaundice

Ruijin Hospital

Not applicable

360

Shanghai

2024-08-01

Recruiting

68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Diagnosing Unilateral Subtype of Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion (PREDICT)

NCT06833437Primary Aldosteronism, Autonomous Cortisol Secretion

Qifu Li

Not applicable

178

Chongqing

2024-08-01

Recruiting

A Prospective Cohort Study of Proton and Photon Therapy for Left-sided Breast Cancer.

NCT06677879Breast Cancer

Shanghai Proton and Heavy Ion Center

Phase 2

780

Shanghai

2024-08-01

Recruiting

Pucotenlimab Plus Radiotherapy and Chemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cance(PUCRT)

NCT06770270Rectal Cancer

DrugPucotenlimab

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

Hangzhou

2024-08-01

Recruiting

A Hierarchical Multi-modal AI Framework for Pathological and Genetic Subtyping of Lung Cancer Based on PET/CT Imaging

NCT07463300Lung Cancer

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

5,500

Guangzhou, Wuhan, Yangzhou, Shenyang, Chengdu, Hangzhou

2024-08-01

Recruiting

An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Characterization of Tumor Heterogeneity for Precision Diagnosis and Treatment Optimization in Liver Cancer.

NCT07101237Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (ICC), Primary Liver Cancer

Peking Union Medical College Hospital

Observational

308

Beijing

2024-08-01

Not yet open

Effect of Low Molecular Heparin on Pregnancy Outcome With Protein S Deficiency

NCT06531525Pregnancy Related, Protein S Deficiency

DrugsEnoxaparin·Aspirin

Peking University People's Hospital

Phase 2

Beijing

2024-08-01

Recruiting

Superselective Adrenal Arterial Embolization for Refractory Hypertension: A Proof-of-Concept Study

NCT06568640Essential Hypertension

Second Affiliated Hospital of Nanchang University

Not applicable

Nanchang

2024-08-01

Recruiting

Efficacy of Ustekinumab Therapy in Patients With Symptomatic Stricturing Crohn's Disease

NCT05387031Crohn Disease, Stricture; Bowel, Intestinal Stricture

DrugUstekinumab

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

239

Beijing, Chongqing, Guangzhou, Huai'an, Suzhou, Yangzhou, Hangzhou

2024-08-01

Recruiting

IMmune Proteomics to Predict neoAdjuvant Chemotherapy and immunoTherapy Response in Gastric Cancer

NCT06662110Gastric Cancer, Gastroesophageal Junction Cancer

Shanghai Zhongshan Hospital

Observational

206

Xuhui District

2024-08-01

Recruiting

Study on the Feelings of Euphoria Caused by Remimazolam During Gastroscopy and Colonoscopy and Their Related Factors

NCT06721195Euphoria, Remimazolam Besylate, Gastrointestinal Endoscopy

Zhangjie Yu

Observational

305

Shanghai

2024-08-01

Recruiting

Sonrotoclax, Zanubrutinib and CD20mab in Untreated MCL Patients

NCT06463691MCL

DrugsSonrotoclax·Zanubrutinib

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-08-01

Not yet open

Neoadjuvant Therapy With Weekly Utidelone Combined With Cisplatin for Patients With Breast Cancer (NeoURANIA)

NCT06510465Breast Cancer

DrugsUtidelone·Pertuzumab·Trastuzumab·Cisplatin

RenJi Hospital

Phase 2

143

Shanghai

2024-08-01

Recruiting

PARPi or Capecitabine Combined With PD-1 Inhibitors as Adjuvant Therapy in High-risk TNBC

NCT06533384Triple-negative Breast Cancer

DrugCapecitabine

Guangdong Provincial People's Hospital

Phase 3

310

Guangzhou

2024-08-01

Recruiting

Radiotherapy or Surgery Combined With Intense Androgen Deprivation Therapy for mCRPC

NCT06992232Prostate Cancer Metastatic Disease

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 2

144

Nanjing

2024-08-01

Recruiting

Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression

NCT06524505Bipolar Depression

Tianjin Anding Hospital

Not applicable

100

Tianjin

2024-08-01

Recruiting

Long-Term Outcomes of Endoscopic-assisted vs Conventional Breast-conserving Surgery in Breast Cancer Patients After Neoadjuvant Therapy: a Randomized, Multicenter, Open Label, Non-inferiority Trial

NCT06716073Breast Cancer Invasive

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not applicable

804

Guangzhou, Shantou

2024-08-01

Recruiting

Tranexamic Acid in Patients With Traumatic Bleeding Based on Dynamic Monitoring of Thromboelastography

NCT06736860Trauma Coagulopathy

DrugTranexamic acid (TXA)

Nanfang Hospital, Southern Medical University

Phase 4

580

Guangzhou

2024-08-01

Active, closed

To Evaluate the Effect and Safety of Telitacicept and Standard Treatment for 6months in IgA Nephropathy

NCT07098897IgA Nephropathy (IgAN)

DrugsTelitacicept·Prednisolone·Methylprednisolone

The Affiliated Hospital of Xuzhou Medical University

Phase 3

150

Xuzhou

2024-08-01

Recruiting

68Ga-NI-FAPI PET/CT: First-in-human Study

NCT06688305Malignant Neoplasm

Drug68Ga-NI-FAPI

First Affiliated Hospital of Fujian Medical University

Early Phase 1

Fuzhou

2024-08-01

Recruiting

Monitoring of Antimicrobial Resistance Based on Metagenomics Analyses in Pneumonia Patients

NCT06566898Pneumonia, Next-generation Sequencing, Microbiome, Antimicrobial Resistance

Shanghai General Hospital, China

Observational

800

Shanghai

2024-08-01

Recruiting

Construction and Application of Database of Hebei Provincial Gastric Cancer Collaborative Network Driven by Artificial Intelligence Technology

NCT06506825The Study Focuses on Gastric Cancer

Qun Zhao

Observational

30,000

Shijiazhuang

2024-08-01

Recruiting

The Impact of Intraperitoneal Spray Combined With Intravenous Lidocaine on Postoperative Pain After Myomectomy

NCT07268495Postoperative Pain

General Hospital of Ningxia Medical University

Not applicable

100

Yinchuan

2024-08-01

Recruiting

Anti-PD-1/PD-L1 Antibodies Plus Anti-VEGF Antibody Treatment in Patients With Advanced-Stage HCC

NCT06537908Hepatocellular Carcinoma

DrugAnti-VEGF

Shanghai Zhongshan Hospital

Observational

Shanghai

2024-08-01

Recruiting

Efficacy and Safety of Local Glucocorticoids for the Treatment of Acute Radiation-Induced Intestinal Injury

NCT06410443Radiation-Induced Intestinal Injury

DrugDexamethasone

General Hospital of Shenyang Military Region

Not applicable

Shenyang

2024-08-01

Recruiting

Adaptive Hypofractionated Radiotherapy for Locally Advanced NSCLC Based on Dynamic Enhanced MRI

NCT06545747Non-small Cell Lung Cancer

Sun Yat-sen University

Phase 3

490

Guangzhou

2024-08-01

Recruiting

Analyse of Diagnosis Value of Keloid on 68Ga-RGD PET-CT

NCT07660406Keloid

Drug68Ga-RGD

Peking Union Medical College Hospital

Phase 1/2

Beijing

2024-08-01

Recruiting

Combination of Inaticabtagene Autoleucel With Autologous Hematopoietic Stem Cell Transplantation for Adolescents or Adults With MRD-Positive B-Cell Acute Lymphoblastic Leukemia in Initial Complete Remission.

NCT06608732B-cell Acute Lymphoblastic Leukemia

DrugInaticabtagene autoleucel

Institute of Hematology & Blood Diseases Hospital, China

Phase 2

Tianjin

2024-08-01

Not yet open

Implementation Research on the Intervention Mode of " Comorbidity-Co-causes-Joint-prevention" Comprehensive Demonstration District of Depression and Obesity Among Children and Adolescents in Beijing

NCT06489990Depression, Obesity, High Risk of Depression, Overweight

Capital Medical University

Not applicable

440

Beijing

2024-08-01

Not yet open

Stem Cell Derived Exome for Treatment of Diabetic Foot

NCT06480123Diabetic Foot, Stem Cell

Second Affiliated Hospital of Guangzhou Medical University

Phase 1/2

Guangzhou

2024-08-01

Recruiting

Association of Lifestyle With Complications in the Diabetic Population

NCT06903364Diabetes Mellitus

Nanfang Hospital, Southern Medical University

Observational

800

Guangzhou

2024-08-01

Recruiting

Lenvatinib Plus DEB-TACE and HAIC vs. Lenvatinib Plus DEB-TACE for Large HCC With PVTT

NCT06492395Hepatocellular Carcinoma Non-resectable

Second Affiliated Hospital of Guangzhou Medical University

Phase 3

178

Guangzhou

2024-08-01

By invitation

Immunochemotherapy ± Salvage Chemoradiation for Local Recurrence of Esophageal Squamous Cell Carcinoma After Definitive Chemoradiotherapy

NCT07016737Esophageal Squamous Cell Carcinoma (ESCC)

DrugsSintilimab·Docetaxel

Ye jinjun

Phase 3

Nanjing

2024-08-01

Active, closed

Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

NCT06282874Carcinoma, Non-Small-Cell Lung, Brain Metastases, Leptomeningeal Metastasis

DrugLorlatinib

Guangdong Association of Clinical Trials

Phase 4

Dongguan, Foshan, Guangzhou

2024-08-01

Recruiting

Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes

NCT06273631Type 1 Diabetes, Diet Intervention, Glucose Control

Yang Tao

Not applicable

Nanjing

2024-08-01

Recruiting

Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage

NCT06906432Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome, Mass Spectrometry, Heart Failure

Beijing Tiantan Hospital

Observational

1,000

Beijing

2024-08-01

Recruiting

Neoadjuvant ChemoRadiotherapy Followed by Immunotherapy and Surgery for Resectable Esophageal Squamous Cell Carcinoma（CRIS-2 Trial）

NCT06509568Esophageal Squamous Cell Carcinoma

Zhejiang Cancer Hospital

Phase 2

Hangzhou

2024-08-01

Recruiting

Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC

NCT06536868Extensive-stage Small-cell Lung Cancer

DrugsEtoposide·Tislelizumab·Cisplatin·Carboplatin

Second Hospital of Shanxi Medical University

Phase 2

Jincheng, Jinzhong, Taiyuan

2024-08-01

By invitation

The Construction and Application of a Mobile Health Management Program for Elderly Depression Based on the Patterns of Cognitive Function Changes

NCT06709027Patients With Depression in the Elderly

Fujian Medical University

Not applicable

Fuzhou

2024-08-01

Recruiting

Selinexor in Combination With R-CHOP as the First-line Therapy for TP53-mutated DLBCL Patients (Smart Trial)

NCT06517511Diffuse Large B Cell Lymphoma

DrugsR-CHOP Protocol·R-Chop·Selinexor

Sun Yat-sen University

Phase 2

Guangzhou, Shanghai

2024-08-01

Recruiting

Hypofractionated Radiotherapy +Chemotherapy+ Camrelizumab as Neoadjuvant Therapy for Pancreatic Cancer

NCT06435260Pancreatic Cancer

DrugCamrelizumab

Hebei Medical University Fourth Hospital

Phase 2

Shijiazhuang

2024-08-01

Active, closed

Predicting HIF-2α Levels in Clear Cell Kidney Cancer Using Machine Learning

NCT07332923Renal Clear Cell Carcinoma, HIF-2α, Radiomics, Nomogram

First Affiliated Hospital of Fujian Medical University

Observational

500

Fuzhou

2024-08-01

Recruiting

Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

NCT06320041Postoperative Pain

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Phase 4

162

Yiwu

2024-08-01

Recruiting

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

NCT06380751Advanced Breast Cancer

DrugsSaruparib·Camizestrant·Exemestane·Anastrozole

AstraZeneca

Phase 3

788

Beijing, Bengbu, Changchun, Changsha, Chengdu, Chongqing, Foshan, Fuzhou

2024-08-01

Recruiting

Effectiveness of MST Versus ECT for Major Depressive Episode

NCT06409325Major Depressive Disorder (MDD)

Shanghai Mental Health Center

Not applicable

210

Shanghai

2024-08-01

Recruiting

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease

NCT06399107Sickle Cell Disease, Sickle-Cell Disease With Crisis

Essen Biotech

Phase 1/2

Beijing

2024-08-01

Recruiting

Ustekinumab With Semi-EN vs Exclusive EN for Preoperative Crohn's Disease Optimization.

NCT06912815Crohn Disease (CD)

Xiang Gao

Not applicable

184

Guangzhou

2024-08-01

Recruiting

Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea

NCT06757491Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain, Functional Magnetic Resonance Imaging, IBS (Irritable Bowel Syndrome)

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-08-01

Active, closed

Efficacy and Safety of LP-003 Injection in Patients With Moderate to Severe Seasonal Allergic Rhinitis

NCT07291284Seasonal Allergic Rhinitis

DrugLP-003

Longbio Pharma

Phase 3

546

Beijing

2024-08-01

Recruiting

Establishment of Precise Histological Evaluation Criteria for NASH Fibrosis Reversal

NCT06707129Non-alcoholic Fatty Liver Disease

Beijing Municipal Administration of Hospitals

Observational

Beijing

2024-08-01

Recruiting

Prospective Real-World Study of HAIC With Raltitrexed or 5-Fluorouracil for the Treatment of Hepatocellular Carcinoma

NCT06519578Hepatocellular Carcinoma

RenJi Hospital

Not applicable

1,115

Shanghai

2024-08-01

By invitation

Evaluation of Clinical Efficacy and Prognosis in Patients With Hypertrophic Obstructive Cardiomyopathy Through Hemodynamic Modeling Reconstructed by CT

NCT06683872Hypertrophic Cardiomyopathy (HCM)

Zhejiang Provincial People's Hospital

Observational

200

Hangzhou

2024-08-01

Recruiting

Neoadjuvant/Adjuvant Cadonilimab Plus Chemotherapy in Patients With Resectable PD-L1 Negative NSCLC

NCT06532591NSCLC

DrugsCadonilimab·Carboplatin

Sichuan Cancer Hospital and Research Institute

Phase 2

Chengdu

2024-08-01

Recruiting

Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC Patients

NCT06389201Nasopharyngeal Carcinoma

DrugHydroxychloroquine

Affiliated Hospital of Nantong University

Not applicable

Nantong

2024-08-01

Recruiting

A Clinical Study on the Efficacy and Safety of Zonisamide as a First Add-On Treatment in Epileptic Seizures

NCT06967012Epilepsies, Partial, Epilepsy, Tonic-Clonic

Affiliated Hospital of Nantong University

Phase 4

Nantong

2024-08-01

Recruiting

Opioid Free Anesthesia on the Quality of Early Recovery

NCT05577962Opioid-free Anesthesia

Beijing Friendship Hospital

Phase 4

160

Beijing

2024-08-01

Active, closed

Methylprednisolone Adjunctive to Endovascular Thrombectomy for Stroke

NCT06360458Acute Ischemic Stroke, Large Infarct Core

DrugMethylprednisolone sodium succinate

Wan-Jin Chen

Phase 3

928

Hefei, Taihe Chengguanzhen, Wuhu, Anxi, Fuqing, Fuzhou, Longyan, Nanping

2024-08-01

Recruiting

Exploring the Genome-wide Association Study of the Population With Clinical Cure Advantage in the Treatment of Chronic Hepatitis B With Long-acting Interferon

NCT06696664Chronic Hepatitis B

DrugPeg-IFNα

Minghui Li

Observational

120

Beijing

2024-08-01

Active, closed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Inhaled XQ-001 in Healthy Subjects

NCT06918366Healthy

Brilliant Inspiration Biotherapeutics

Phase 1

Chendu

2024-08-01

Not yet open

RE001 T Cell Injection for the Treatment of KRAS G12V Mutated Solid Tumors

NCT06545201KRAS G12V, T Cell Therapy

Henan Cancer Hospital

Phase 1

Zhengzhou

2024-08-01

Recruiting

Anti-CD38 Antibody Treating Children With Primary Immune Thrombocytopenia (ITP)

NCT06838962Immune Thrombocytopenia, Treatment

DrugDaratumumab

Institute of Hematology & Blood Diseases Hospital, China

Phase 2

Tianjin

2024-08-01

Recruiting

Biomarkers Related to PSCI: An fNIRS Study

NCT06703307Stroke, Cognitive Decline

Dingqun Bai

Observational

Chongqing

2024-08-01

Recruiting

Comparative Effectiveness of Intervention in Multi-level Hospitals for Acute Traumatic Brain Injury(Metric-TBI)

NCT06429774Traumatic Brain Injury

Beijing Tiantan Hospital

Observational

2,000

Beijing, Baoding, Cangzhou, Chengde, Handan, Langfang, Qinhuangdao, Shijiazhuang

2024-08-01

Recruiting

Clinical Study of Lewis Antigen Assay Combined With CA19-9 Assay to Assess Prognosis in Patients With Pancreatic Cancer

NCT06515587PDAC

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Not applicable

Shanghai

2024-08-01

Active, closed

S365: A Multicenter Longitudinal Cohort of Sleep Health

NCT06760000Sleep Disorder, Sleep

Peking University

Observational

5,000

Beijing

2024-08-01

Not yet open

A Real-world Research on the Prevention and Treatment of Peritoneal Metastasis and Malignant Ascites by Intraperitoneal Infusion of rmhTNF in Gastric and Colorectal Malignant Tumors

NCT06496919Gastric Cancer

Wuhan University

Observational

300

Wuhan

2024-08-01

Recruiting

Idiopathic Scoliosis New Onset and Melatonin Phase Delay in Children

NCT06502613Scoliosis Idiopathic, Circadian Rhythm, Melatonin

Second Affiliated Hospital of Wenzhou Medical University

Observational

956

Wenzhou

2024-08-01

Active, closed

A Clinical Study for the Treatment of Pediatric and Adolescent Patients With Type 1 Gaucher Disease

NCT06528080Gaucher Disease

Shanghai Jiao Tong University School of Medicine

Early Phase 1

Shanghai

2024-08-01

Recruiting

Evaluation of Trop-2 ADC in Breast Cancer Patients With Brain Metastases: A Real-World Study

NCT07251868Breast Cancer, Brain Metastases From Breast Cancer, Trop2

DrugSacituzumab Govitecan

Peking University Cancer Hospital & Institute

Observational

100

Beijing

2024-08-01

Recruiting

Effect of the Postbiotics on Complications Treatment in Elderly Hemodialysis Patients

NCT06975995Hemodialysis Complication

Peking University First Hospital

Not applicable

Beijing

2024-08-01

Recruiting

THBC/CGF for Alveolar Bone Regeneration: A Real-World Study

NCT07779421Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted

Stomatological Hospital Affiliated with Fujian Medical University

Not applicable

136

Fuzhou

2024-08-01

Recruiting

A Multicenter, Randomized, Crossover Clinical Trial Study of Digital Intelligence Software in Patients With MAFLD

NCT07233486MAFLD

The Affiliated Hospital of Hangzhou Normal University

Not applicable

2,000

Hangzhou

2024-08-01

Active, closed

Multi-omics Profiling of Patients With Aplastic Anemia Before and After CD7-CAR-T Therapy

NCT07139600Aplastic Anaemia, CAR-T, CD7 Positive

Xuzhou Medical University

Observational

Xuzhou

2024-08-01

Not yet open

Early Diagnosis of Pancreatic Cancer Via Deciphering Multi-modal Immunological Signatures

NCT06495749Pancreatic Cancer Resectable

Zhejiang University

Observational

3,000

Hangzhou

2024-08-01

Recruiting

Comparison Study of EAP and Disease-Specific Chemotherapy Regimens in Hematopoietic Stem Cell Mobilization for Lymphoma

NCT06520163Non-Hodgkin's Lymphoma, Hematopoietic Stem Cell Mobilization

DrugsPEG-rhG-CSF·G-Csf·Ara-C·Cytarabine

The Affiliated People's Hospital of Ningbo University

Phase 3

Dongyang, Hangzhou, Huzhou, Jiaxing, Jinhua, Lishui, Ningbo, Shaoxing

2024-08-01

Recruiting

Predictive Algorithms for Critical Rehabilitation Outcomes

NCT06532994Intensive Care, Mechanical Ventilation, Rehabilitation, Algorithms

Wuhan University

Observational

250

Wuhan

2024-08-01

By invitation

Clinical Efficacy and Mechanism of rTMS Based on dlPFC in the Intervention of Generalized Anxiety Disorder With Insomnia

NCT06931236Generalized Anxiety Disorder (GAD), Insomnia, Repetitive Transcranial Magnetic Stimulation (rTMS)

Yanghua Tian

Not applicable

Hefei

2024-08-01

Recruiting

Dalpiciclib Plus Toremifene for First-line Advanced HR Positive and HER2 Negative Breast Cancer

NCT06495515CANCER, BRAEST CANCER, Late Frontline

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-08-01

Active, closed

A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy

NCT06553495Pain

Jie Chen

Not applicable

Chongqing

2024-08-01

Recruiting

Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease

NCT06874803Parkinson's Disease (PD)

Jiani Wu

Not applicable

Beijing

2024-08-01

Not yet open

Antiviral Therapy in Infants With HBV Infection

NCT06503796HBV

DrugsInterferon·Lamivudine

Beijing 302 Hospital

Phase 4

Beijing

2024-08

Recruiting

Exploring the Association of Imaging and Tumor Microenvironment in Liver Cancer Using Radiogenomic Approach（Radiogenomics-Liver）

NCT06536998Liver Cancer

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

150

Wuhan

2024-08

Recruiting

Comparison Study of EAP and CG Regimens for Mobilizing Hematopoietic Stem Cells in Multiple Myeloma Patients

NCT06520176Multiple Myeloma, Hematopoietic Stem Cell Mobilization

DrugsPEG-rhG-CSF·Pegfilgrastim·G-Csf·Ara-C

The Affiliated People's Hospital of Ningbo University

Phase 3

Dongyang, Hangzhou, Huzhou, Jiaxing, Jinhua, Lishui, Ningbo, Shaoxing

2024-08

Not yet open

A Multicenter Randomized Controlled Study of Interventional Treatment for Operable Stage Ⅱ-Ⅲ Non-small Cell Lung Cancer With Potential Recurrence as Minimal Residual Disease(MRD) Positive

NCT06524518DFS

DrugImmunization

Xuanwu Hospital, Beijing

Phase 2

213

Beijing

2024-08

Not yet open

A Prospective Cohort Study Comparing AI Prediction Model With Imaging Assessment to Diagnose Lymph Node Metastasis in Cervical Cancer

NCT06541288Uterine Cervical Neoplasms

Obstetrics & Gynecology Hospital of Fudan University

Not applicable

230

Shanghai

2024-08

Not yet open

Clinical Study of 18F-Alfatide Injection PET/CT

NCT06416852Non-Small Cell Lung Cancer NSCLC

DrugFluorodeoxyglucose

Yantai LNC Biotechnology Singapore PTE. LTD.

Phase 3

428

Wuhan

2024-08

Not yet open

Tislelizumab and Induction Chemotherapy for Larynx Preservation in Resectable Advanced Laryngeal/Hypopharyngeal Cancer

NCT06554028Laryngeal Cancer, Hypopharynx Cancer, Laryngeal Neoplasms

DrugTislelizumab

Henan Cancer Hospital

Phase 2

Zhengzhou

2024-08

Recruiting

Exploring the Association of Imaging and Tumor Microenvironment in Urologic Cancer Using Radiogenomic Approach（Radiogenomics-Urinary）

NCT06537037Urologic Cancer

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

150

Wuhan

2024-08

Recruiting

The Efficacy and Safety of LM-302 in Combination With Candonilimab and Capecitabine for First-Line Treatment in Patients With Unresectable Advanced, Recurrent, or Metastatic CLDN18.2-Positive Gastric or Gastroesophageal Junction Adenocarcinoma

NCT06587425Gastric or Gastroesophageal Junction Adenocarcinoma

DrugsCandonilimab·LM-302·Capecitabine

Shanghai Zhongshan Hospital

Phase 2

Shanghai

2024-07-31

Recruiting

Clinical Trial of Pegylated Interferon α-2b Via Nebulization for Treatment of Hand, Foot, and Mouth Disease .

NCT07008755HFMD

DrugPeginterferon α-2b

Zhengzhou Children's Hospital, China

Not applicable

Chengdu, Liangshan, Zhengzhou, Ziyang

2024-07-31

Active, closed

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.

NCT06517758Generalized Myasthenia Gravis

DrugIptacopan

Novartis Pharmaceuticals

Phase 3

146

Hefei, Guangzhou, Shenzhen, Shijiazhuang, Changsha, Suzhou, Xi'an, Xianyang

2024-07-31

Recruiting

Anlotinib With Trastuzumab Deruxtecan for Previously Treated HER2-Low Advanced Breast Cancer

NCT06331169Breast Cancer

DrugsAnlotinib·Trastuzumab deruxtecan

Fudan University

Phase 1

Shanghai

2024-07-31

Recruiting

Phase 2 Study of WGI-0301 for Advanced HCC

NCT06309485Advanced Hepatocellular Carcinoma (HCC)

Zhejiang Haichang Biotech Co., Ltd.

Phase 2

Shanghai, Changsha, Chengdu, Hangzhou, Harbin, Nanchang, Wuhan

2024-07-31

Recruiting

CPVI With Modified Linear Ablation Versus CPVI in Patients With Long-standing Persistent Atrial Fibrillation (SINUS)

NCT06516822Long-standing Persistent Atrial Fibrillation, Ablation

The First Affiliated Hospital with Nanjing Medical University

Not applicable

320

Beijing, Guangzhou, Shenzhen, Zhengzhou, Nanjing, Dalian, Jinan, Xi’an

2024-07-31

Active, closed

The Intervention Effect and Potential Neural Mechanisms of Music Therapy in Children and Adolescents With Mood Disorders

NCT06756698Mood Disorders in Children and Adolescents

Shanghai Mental Health Center

Not applicable

Shanghai

2024-07-31

Recruiting

Biomarkers in Autoimmune Disease of Nervous System

NCT06502015Autoimmune Diseases of the Nervous System, Neuromyelitis Optica Spectrum Disorder, Multiple Sclerosis, Guillain-Barre Syndrome

Tongji Hospital

Observational

50,000

Wuhan

2024-07-31

Not yet open

Darxicilib Combined With Abiraterone Acetate Tablets (II) for the Treatment of Advanced Metastatic Castration-resistant Prostate Cancer.

NCT06500247The Efficacy of Abiraterone Acetate Combined With Dalpicilib in the Treatment of Patients With Metastatic Castration-resistant Prostate Cancer

DrugsDalpicilib·Abiraterone acetate·Prednisone

Qilu Hospital of Shandong University

Phase 2

Jinan

2024-07-31

Recruiting

Phase IV Study of rhGH Injection in Adult Short Bowel Syndrome

NCT07691125Short Bowel Syndrome (SBS) in Adults

DrugRhGH

Changchun GeneScience Pharmaceutical Co., Ltd.

Phase 4

100

Xiamen, Nanjing

2024-07-31

Active, closed

A Real-world Study to Evaluate the Effectiveness of Intravascular Lithotripsy in Moderate to Severe Calcification Lesion of Lower Extremity Femoropopliteal Artery

NCT06636968Peripheral Arterial Disease

Shanghai Zhongshan Hospital

Observational

200

Shanghai

2024-07-31

Recruiting

Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease

NCT06527768Chronic Kidney Diseases, Metabolic Syndrome

Chinese University of Hong Kong

Not applicable

Chengdu

2024-07-31

Active, closed

SAVE-PCI: NyokAssist™ Small-Bore VAD vs. IABP in Elective High-Risk PCI

NCT07010965High-Risk PCI

magAssist, Inc.

Not applicable

236

Beijing, Changsha, Guangzhou, Hangzhou, Harbin, Lanzhou, Shanghai, Taiyuan

2024-07-31

Active, closed

A Study of BL-B01D1 in Combination With Osimertinib Mesylate Tablets in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

NCT06498986Non-small Cell Lung Cancer

DrugsIza-bren·Osimertinib

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 2

Shanghai

2024-07-31

Recruiting

Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules

NCT06423235Thyroid Nodule

Xintian Pharmaceutical

Phase 4

234

Chongqing, Xiamen, Guangzhou, Shenzhen, Shunde, Wuhan, Nanjing, Xuzhou

2024-07-30

Recruiting

A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.

NCT06470191Primary Membranous Nephropathy

DrugsCyclosporin·B007

Shanghai Jiaolian Drug Research and Development Co., Ltd

Phase 2/3

216

Beijing, Changchun, Guangzhou, Hangzhou, Jinan, Nanning, Nantong, Qingdao

2024-07-30

By invitation

Clinical Trial to Evaluate the Effectiveness and Safety of a Remote Automated Ultrasound Diagnostic System for Automated Ultrasound Examinations: a Prospective, Multicenter Study

NCT06487312Ultrasound, Thyroid, Carotid Artery, Liver

Tongji Hospital

Observational

1,000

Wuhan

2024-07-30

Recruiting

IM19 CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus (SLE)

NCT06513429Refractory Systemic Lupus Erythematosus

Peking University Third Hospital

Not applicable

Beijing

2024-07-30

Recruiting

68Ga-C1 PET/ CT Imaging in Clear Cell Renal Cell Carcinoma

NCT06519760Carbonic Anhydrase IX, PET-CT, Clear Cell Renal Cell Carcinoma

Peking University First Hospital

Not applicable

200

Beijing

2024-07-30

Recruiting

A Trial to Assess Efficacy, Safety, Pharmacokinetics of Octreotide Subcutaneous Injection in Patients With Gastroentero-pancreatic Neuroendocrine Tumor (GEP-NET)

NCT06505395Gastrointestinal Neuroendocrine Pancreatic Tumor

CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Phase 2

Beijing

2024-07-30

Not yet open

Electroacupuncture Treatment of Behavioral and Psycological Symptoms in Patients With Alzheimer's Disease

NCT06523309BPSD (Behavioral and Psycological Symptoms of Dementia), Alzheimer's Dementia

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Observational

1,000

Beijing, Fuzhou, Harbin

2024-07-30

Recruiting

Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation

NCT06308952Cerebrovascular Event, Stent Stenosis, Ischemic Stroke, Hemorrhagic Stroke

DrugsLipitor·Atorvastatin

Duan Chuanzhi

Phase 4

354

Guangzhou

2024-07-30

Recruiting

A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer

NCT06512051Advanced or Metastatic Non-small Cell Lung Cancer

DrugsSHR-A2102·Adebrelimab·Bevacizumab·Cisplatin

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 1/2

248

Beijing

2024-07-30

Recruiting

Risk Warning Model of Postoperative Delirium and Long-term Cognitive Dysfunction in Elderly Patients

NCT06423547Postoperative Delirium, Postoperative Neurocognitive Disorder, Surgery

Xuanwu Hospital, Beijing

Observational

10,000

Beijing

2024-07-30

Active, closed

Early Combined Use of Dexamethasone Intravitreal Implant and Anti-VEGF in the Treatment of DME.

NCT06846073Diabetic Macular Edema (DME)

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

Hangzhou

2024-07-30

Recruiting

Under Whole-course of Immunotherapy, Gradient Fractionated RT with CCT Versus CFRT with CCT for LANPC Who Achieved PR Post Induction Chemotherapy.

NCT06675214Nasopharyngeal Carcinoma, De-escalation Therapy

Sun Yat-sen University

Phase 3

586

Zhuhai

2024-07-30

Recruiting

Comparison of VA (Venetoclax, Azacitidine), VACl (VA, Cladribine), VACh (VA, Chidamide), and Alternating VACl/VACh in Newly Diagnosed Acute Myeloid Leukemia

NCT06532552Acute Myeloid Leukemia, Adult, Newly Diagnosed

DrugVenetoclax/Azacitidine

The First Affiliated Hospital of Soochow University

Phase 2

172

Suzhou

2024-07-29

Recruiting

Efficacy of Two HMOs in Chinese Infants

NCT06361719Healthy Infants

Société des Produits Nestlé (SPN)

Not applicable

262

Shanghai

2024-07-29

Recruiting

A Study of IBI3003 in Subjects With Relapsed or Refractory Multiple Myeloma

NCT06083207Multiple Myeloma

DrugIBI3003

Innovent Biologics (Suzhou) Co. Ltd.

Phase 1/2

116

Beijing, Nanning, Wuhan, Nanjing, Suzhou, Xuzhou, Nanchang, Shanghai

2024-07-29

Recruiting

Trial for Surgical Treatment of Reducible Atlantoaxial Dislocation

NCT06003491Atlantoaxial Dislocation

Xuanwu Hospital, Beijing

Not applicable

164

Beijing

2024-07-29

Recruiting

A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations

NCT06430437Non-Small Cell Lung Cancer With HER2- Mutations

DrugTrastuzumab Rezetecan

Jiangsu HengRui Medicine Co., Ltd.

Phase 3

300

Shanghai

2024-07-29

Recruiting

Efficacy and Safety of JAK Inhibitors in Patients With AA: RWE Study

NCT06573593Alopecia Areata, Janus Kinase Inhibitors

DrugsRitlecitinib·Abrocitinib·Tofacitinib·Baricitinib

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

150

Hangzhou

2024-07-29

Recruiting

The Efficacy and Safety of Pola-ZR2 Versus ZR2 in the Treatment of Old Patients With de Novo Diffuse Large B-cell Lymphoma

NCT06522555Diffuse Large B-Cell Lymphoma

Ruijin Hospital

Phase 3

100

Shanghai

2024-07-29

Recruiting

Clinical Trial Evaluating the Safety and Efficacy of Tumor Thermosensitive Embolic Agent in Transcatheter Arterial Chemoembolization for Primary Liver Cancer

NCT07356531Liver Cancer

JIANGSU SHENMING Medical Technology CO., Ltd

Not applicable

216

Hefei, Beijing, Nanning, Guiyang, Shijiazhuang, Anyang, Luoyang, Zhengzhou

2024-07-29

Active, closed

Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer

NCT06507371Rectal Cancer

DrugsCapecitabine·Oxaliplatin

Sir Run Run Shaw Hospital

Phase 3

170

Hanzhou

2024-07-29

Active, closed

Clinical Trial of Protective Efficacy of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)

NCT06524947Acute Gastroenteropathy Due to Norovirus

Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Phase 3

6,600

Nanning, Changsha, Chengdu

2024-07-27

Recruiting

A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer

NCT06492005Triple-Negative Breast Cancer

DrugsPD-1 inhibitior·9MW2821

Mabwell (Shanghai) Bioscience Co., Ltd.

Phase 2

160

Shanghai

2024-07-26

Recruiting

Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD

NCT06692114Obsessive-Compulsive Disorder

Zhen Wang

Not applicable

Shanghai

2024-07-26

Recruiting

Development and Prospective Validation of a Digital Pathology-based Artificial Intelligence Diagnostic Model for Pan-cancer Lymphatic Metastasis

NCT06517979Cancer, Lymphatic Metastasis

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Observational

10,000

Guangzhou

2024-07-26

Recruiting

Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne Muscular Dystrophy

NCT06641895Duchenne Muscular Dystrophy (DMD)

Shanghai Jiao Tong University School of Medicine

Early Phase 1

Shanghai

2024-07-25

Recruiting

Intravascular Ultrasound-Guided PCI in Patients With Chronic Kidney Disease

NCT06567938Coronary Artery Disease, Chronic Kidney Diseases

First Affiliated Hospital Xi'an Jiaotong University

Not applicable

1,528

Xi'an

2024-07-25

Recruiting

Eliminating Breast Surgery for Breast Cancer Patients With Clinical Complete Response to Neoadjuvant Systemic Therapy

NCT06498154Breast Cancer

Tianjin Medical University Cancer Institute and Hospital

Phase 2

200

Tianjin

2024-07-25

Recruiting

Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer

NCT06407518Preoperative, Sleep Disturbance, Anxiety, Midazolam

DrugMidazolam

Sixth Affiliated Hospital, Sun Yat-sen University

Not applicable

280

Guangzhou

2024-07-24

Recruiting

A Study on the Infusion Regimen of Piperacillin-Tazobactam in Patients Aged 65 and Older With Pneumonia

NCT06972537Pneumonia

Shandong University

Not applicable

Jinan

2024-07-24

Recruiting

Efficacy and Safety of Organoid-Based Drug Sensitivity Screening to Guide the Treatment of mCRPC Patients Progressed After First-line Treatment

NCT06529549Metastatic Castration-resistant Prostate Cancer

Sun Yat-sen University

Observational

Guangzhou

2024-07-24

Recruiting

Adebrelimab Combined With Famitinib and Irinotecan in Advanced Gastric Cancer After Failure of First-Line Therapy

NCT07309185Stomach Neoplasms

DrugsAdebrelimab·Irinotecan

Shandong Tumor Hospital

Phase 2

Jinan

2024-07-24

Recruiting

A Study of MRG006A in the Treatment of Patients With Advanced Solid Tumors

NCT07093970Advanced Solid Tumors

DrugMRG006A

Lepu Biopharma Co., Ltd.

Phase 1/2

343

Beijing, Shanghai

2024-07-24

Recruiting

Donafenib Combined With Anti-PD-1 Antibody for Neoadjuvant Therapy in Locally Advanced Thyroid Cancer

NCT06787911Thyroid Cancer

Yu Wang

Phase 2

Shanghai

2024-07-24

Recruiting

Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors

NCT06821048Colorectal Cancer, Stomach Cancer, Pancreatic Cancer, Metastatic Cancer

Weijia Fang, MD

Phase 1

Hangzhou

2024-07-24

Active, closed

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

NCT06459180Cervical Cancer

DrugsTisotumab Vedotin·Vinorelbine·Topotecan·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

686

Hefei, Beijing, Chongqing, Fuzhou, Xiamen, Guangzhou, Zhanjiang, Nanning

2024-07-24

Recruiting

Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection

NCT06454578Carcinoma, Hepatocellular

DrugsApatinib·Adebrelimab

Qilu Hospital of Shandong University

Phase 2

Jinan

2024-07-24

Recruiting

A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Lower Expression Gastrointestinal Cancer and Other Solid Tumors

NCT06500052Esophageal Cancer, Gastric Cancer, Pancreatic Cancer, Colorectal Cancer

DrugBL-M17D1

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Guangzhou

2024-07-24

Not yet open

A Study to Evaluate the Safety and Efficacy of ATHENA CAR-T in Subjects With Systemic Lupus Erythematosus

NCT06373991Lupus Erythematosus, Systemic

DrugsFludarabine·Cyclophosphamide

EdiGene Inc.

Phase 1

Luoyang

2024-07-24

Recruiting

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

NCT06386146Solid Tumors

Jacobio Pharmaceuticals Co., Ltd.

Phase 1/2

144

Beijing, Guangzhou, Zhengzhou, Shenyang, Jinan, Shanghai

2024-07-24

Recruiting

Adebrelimab Combined With Chemotherapy and Concurrent SBRT for Neoadjuvant Treatment of Limited-stage Small Cell Lung Cancer

NCT06562920Efficacy and Safety of Neoadjuvant Immunotherapy for Small Cell Lung Cancer

Zhejiang Cancer Hospital

Phase 2

Hangzhou

2024-07-24

Active, closed

Accuracy, Stability and Safety of Orthodontic Mini-implant Template in the Infrazygomatic Crest Zone

NCT06786221Dental Implants, Dental Implantation

Universiti Sains Malaysia

Not applicable

Beijing

2024-07-24

Recruiting

A Clinical Trial of SIBP-A17 Injection in the Treatment of Advanced Solid Tumor Patients.

NCT06512116Advanced Solid Tumor

Shanghai Institute Of Biological Products

Phase 1

196

Beijing

2024-07-23

Recruiting

PulseSelect™ PFA Global Registry

NCT06393920Atrial Fibrillation

Medtronic Cardiac Ablation Solutions

Observational

1,950

Beijing, Fuzhou, Harbin, Kunming, Nanjing, Shanghai, Shenzhen, Ürümqi

2024-07-23

Recruiting

PET Imaging Targeting Granzyme B Predicts Immunotherapy Efficacy in Diffuse Large B-cell Lymphoma

NCT06755775Diffuse Large B-Cell Lymphoma

Ruijin Hospital

Observational

150

Shanghai

2024-07-23

Active, closed

Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLC

NCT06376084Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Respiratory Tract Neoplasms, Thoracic Neoplasms

AstraZeneca

Observational

532

Shanghai

2024-07-23

Recruiting

A Study of IMM2510 + IMM27M Combination Therapy in Patients With Advanced Solid Tumors

NCT06764836Advanced Solid Tumors, HCC

DrugIMM2510

ImmuneOnco Biopharmaceuticals (Shanghai) Inc.

Phase 1

108

Shanghai

2024-07-23

Active, closed

Neoadjuvant SBRT Combined With Lenvatinib and Pucotenlimab for Resectable Hepatocellular Carcinoma

NCT06524466Resectable Hepatocellular Carcinoma, Macrovascular Invasion, CNLC IIIA Stage

Sun Yat-sen University

Phase 2

Guangzhou

2024-07-23

Recruiting

Application of Autologous Adipose Stromal Vascular Fraction in the Treatment of Premature Ovarian Insufficiency

NCT06481969Premature Ovarian Insufficiency

Rui Yang

Not applicable

260

Beijing

2024-07-23

Active, closed

Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL)

NCT06054113B Precursor Acute Lymphoblastic Leukemia, Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia

DrugBlinatumomab

Amgen

Phase 2

Hefei, Chongqing, Guangzhou, Wuhan, Suzhou, Shanghai, Tianjin

2024-07-23

Recruiting

Adebrelimab and Chemoradiotherapy in High-risk LANPC

NCT06349889Nasopharyngeal Carcinoma, Nasopharyngeal Cancer

DrugAdebrelimab

Sun Yat-sen University

Phase 2

Xiamen, Guangzhou, Chengdu

2024-07-23

Recruiting

Efficacy and Safety of Angiotensin II Injection Versus Placebo in Patients With Refractory Distributed Shock

NCT06351150Vasodilatory Shock

DrugAngiotensin II

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 3

214

Hefei, Wuhu, Beijing, Chongqing, Fuzhou, Lanzhou, Guangzhou, Qingyuan

2024-07-23

Recruiting

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

NCT06427941Metastatic Hepatocellular Carcinoma, Local Advanced Hepatocellular Carcinoma, Alpha-fetoprotein (AFP)-Producing Gastric Cancer, Extragonadal Yolk Sac Tumors

DrugsTislelizumab·Bevacizumab

BeOne Medicines

Phase 1/2

630

Hefei, Chongqing, Fuzhou, Guangzhou, Nanning, Shijiazhuang, Harbin, Wuhan

2024-07-23

Recruiting

A Clinical Study Evaluating the Safety, Tolerability, and Initial Efficacy of JWK008 in Patients With Mucopolysaccharidosis Type I

NCT06519552Mucopolysaccharidosis Type I

West China Hospital

Phase 1

Chengdu

2024-07-22

Recruiting

Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

NCT06484153To Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal Carcinoma, To Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal Cancer, Combination of Fruquintinib and Anti-PD-1 Antibody Was Reported to Improve Patient Prognosis in Colorectal Cancer

DrugsPirfenidone·Fruquintinib·Pembrolizumab

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 2

Wuhan

2024-07-22

Recruiting

Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction

NCT06368544Anterior Cruciate Ligament Injuries, Cartilage Degeneration

Peking University Third Hospital

Not applicable

Beijing

2024-07-22

Recruiting

A Study of TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract Cancer

NCT06431490Biliary Tract Cancer

DrugTQB2102

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 1/2

102

Fuyang, Hefei, Beijing, Chongqing, Fuzhou, Lanzhou, Guangzhou, Jiangmen

2024-07-22

Recruiting

Born In Guangzhou Intervention Study

NCT05503849Pregnancy Outcomes, Child Development, Pregnancy Complications

Guangzhou Women and Children's Medical Center

Not applicable

1,160

Guangzhou

2024-07-22

Recruiting

Electroacupuncture for Dysmenorrhea Secondary to Adenomyosis

NCT06364592Dysmenorrhea, Adenomyosis, Electroacupuncture

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Not applicable

Beijing

2024-07-21

Recruiting

Prediction of Significant Liver Fibrosis

NCT06509230Liver Fibrosis

Huang Haijun

Observational

700

Hangzhou

2024-07-20

Recruiting

The Impact of Airway Allergic Diseases on Children's and Parents' Quality of Life

NCT06535087Pediatric Asthma, Rhinitis, Allergic, Quality of Life

Wenjing Zhou

Observational

600

Shanghai

2024-07-20

Recruiting

Clinical Study of Mitoxantrone Hydrochloride Liposome Combined with PD-1 Blockade in Recurrent or Metastatic NPC

NCT06472713Recurrent or Metastatic Nasopharyngeal Carcinoma

DrugsMitoxantrone Hydrochloride Liposome·Venetocalx

Ming-Yuan Chen

Phase 2

Zhuhai

2024-07-20

Recruiting

Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease

NCT06499233Pneumonia, Pneumocystis, Autoimmune Inflammatory Rheumatic Disease, Autoimmune Diseases, Connective Tissue Disease

DrugsTMP/SMX·Trimethoprim-sulfamethoxazole

Tongji Hospital

Phase 4

800

Wuhan

2024-07-20

Recruiting

Adjuvant Treatment of Patients With High Risk of Recurrent Hepatocellular Carcinoma With Donafenib in Combination With Envafolimab

NCT06498622Hepatocellular Carcinoma

DrugsDonafenib·Envafolimab

Anhui Provincial Hospital

Phase 2

Fuyang, Hefei

2024-07-20

Recruiting

Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus

NCT06400537Systemic Lupus Erythematosus

DrugA-319

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 1

Wuhan, Taiyuan

2024-07-20

Not yet open

Plasmodium Immunotherapy for Advanced Ovarian Cancer

NCT05924776Advanced Ovarian Cancer

CAS Lamvac (Guangzhou) Biomedical Technology Co., Ltd.

Phase 2/3

Guangzhou

2024-07-20

Not yet open

Electroacupuncture for the Treatment of Agitated Symptoms of Alzheimer's Disease

NCT06495957Agitation Associated With Alzheimer's Dementia, Alzheimer's Dementia

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Not applicable

224

Beijing, Fuzhou, Harbin

2024-07-20

Recruiting

An In-situ Detection for MicroRNA

NCT06529614Breast Cancer

Tongji Hospital

Observational

100

Wuhan

2024-07-20

Recruiting

Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC

NCT06542588Rectal Cancer

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 2

Wuhan, Hubei

2024-07-19

Recruiting

Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA

NCT07291063Cholangiocarcinoma

Shanghai Zhongshan Hospital

Observational

Shanghai

2024-07-19

By invitation

Cross Validation of Body Composition Measurement

NCT06453564Body Composition

John R. Speakman

Observational

Shenzhen

2024-07-19

Recruiting

A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients

NCT06441812Eosinophilic Asthma Patients

DrugSHR-1703

Guangdong Hengrui Pharmaceutical Co., Ltd

Phase 2

200

Chengdu

2024-07-19

Recruiting

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

NCT06282575Biliary Tract Cancer

DrugsZanidatamab·Durvalumab·Gemcitabine·Cisplatin

Jazz Pharmaceuticals

Phase 3

286

Hefei, Beijing, Lanzhou, Harbin, Changsha, Changchun, Jinan, Chengdu

2024-07-19

Recruiting

IB/IIa Study of MG-K10 in Adolescent Moderately Severe Patients

NCT06765005Atopic Dermatitis

DrugMG-K10

Shanghai Mabgeek Biotech.Co.Ltd

Phase 1/2

Hangzhou

2024-07-19

Recruiting

The Application Value of 68Ga-grazytracer PET in Immunotherapy for Stage III Non-small-cell Lung Cancer

NCT06623487Carcinoma, Non-Small-Cell Lung, PET / CT, Neoadjuvant Immunotherapy

Ruijin Hospital

Observational

Shanghai

2024-07-19

Recruiting

A Study of HS-10516 in Patients With VHL Syndrome Associated Tumors

NCT06553339Von Hippel Lindau-Deficient Clear Cell Renal Cell Carcinoma

DrugHS-10516

Jiangsu Hansoh Pharmaceutical Co., Ltd.

Phase 1

Beijing

2024-07-19

Recruiting

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

NCT06979323Asthma

DrugDepemokimab

GlaxoSmithKline

Phase 3

150

Guangzhou, Shanghai, Tianjin

2024-07-19

Active, closed

aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial

NCT06288659Aneurysmal Subarachnoid Hemorrhage, Intacranial Hypertension

Huashan Hospital

Not applicable

372

Shanghai

2024-07-19

Active, closed

Obinutuzumab, Zanubrutinib, and Lenalidomide Followed Short-Cycle of Obinutuzumab and Cytarabine in Newly Diagnosed Mantle Cell Lymphoma

NCT06504199Mantle Cell Lymphoma

DrugsCar-T·Zanubrutinib·Obinutuzumab·Cytarabine

Institute of Hematology & Blood Diseases Hospital, China

Phase 2

Tianjin

2024-07-18

Recruiting

VA Combined With PD-1 Inhibitor for the Treatment of Relapsed and Refractory AML and High-risk MDS

NCT06536959Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Myelodysplastic Syndromes, Minimal Residual Disease

DrugVenetoclax

Beijing 302 Hospital

Phase 2

Beijing

2024-07-18

Recruiting

Cilostazol vs. Aspirin in Acute Non-cardioembolic Stroke With Cerebral mIcrobleeds

NCT06530537Cerebral Microbleeds, Stroke

DrugsCilostazol·Aspirin

Zhejiang Provincial People's Hospital

Phase 3

848

Hangzhou

2024-07-18

Recruiting

Digital Therapy in Self-management of COPD Patients

NCT06776601Chronic Obstructive Pulmonary Disease

China-Japan Friendship Hospital

Not applicable

600

Beijing

2024-07-18

Recruiting

A Study of BL-B16D1 in Patients With Locally Advanced or Metastatic Solid Tumors

NCT06475131Solid Tumor

DrugBL-B16D1

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Guangzhou

2024-07-18

Recruiting

RET Inhibitor for Neoadjuvant Therapy in Locally Advanced RET-altered Thyroid Cancer

NCT06530316Thyroid Cancer

Fudan University

Observational

Shanghai

2024-07-18

Recruiting

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

NCT06226883Inflammatory Bowel Diseases, Crohn's Disease

DrugZotemtegrast

Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Phase 2

385

2024-07-18

Recruiting

Cetuximab, Irinotecan, Toripalimab in RAS/BRAF Wild-type Ultraselected Right-sided Colorectal Cancer Study

NCT06547203Colorectal Cancer Metastatic

DrugsErbitux·Irinotecan·Cetuximab·Toripalimab

Sun Yat-sen University

Phase 2

Guangzhou

2024-07-18

Recruiting

An Open-label, Single-arm Study of JWCAR201 in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma

NCT06517004Diffuse Large B Cell Lymphoma

DrugJWCAR201

Fudan University

Phase 1

Shanghai

2024-07-18

Recruiting

Peginterferon α-2b Injection for Aerosol Therapy in Pediatric Respiratory Syncytial Virus Pneumonia

NCT06881056Respiratory Syncytial Virus (RSV)

DrugPeginterferon α-2b

West China Second University Hospital

Not applicable

Chengdu

2024-07-17

Recruiting

A Clinical Study of SPH5030 Tablets in the Treatment of Her2-positive/Mutated Biliary Tract OR Colorectal Cancer Patients.

NCT06434597Biliary Tract or Colorectal Cancer With Her2-positive/Mutated

DrugSPH5030

Shanghai Pharmaceuticals Holding Co., Ltd

Phase 2

Beijing, Changsha, Changzhi, Fuzhou, Guangzhou, Hangzhou, Harbin, Hefei

2024-07-17

Recruiting

IVI-guided Versus Angiography-guided PCI in Patients With Diabetes Mellitus

NCT06380868Diabetes

Nanjing First Hospital, Nanjing Medical University

Not applicable

1,332

Nanjing

2024-07-17

Recruiting

RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CR

NCT06571825Acute Myeloid Leukemia

DrugVenetoclax

He Huang

Phase 4

118

Hangzhou

2024-07-17

Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT06252649Metastatic Colorectal Cancer

DrugsSotorasib·Panitumumab·Bevacizumab-awwb·Mvasi

Amgen

Phase 3

450

2024-07-17

Active, closed

A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

NCT06456580Generalized Myasthenia Gravis

DrugTelitacicept

Vor Biopharma

Phase 3

191

Hefei, Beijing, Chongqing, Fuzhou, Lanzhou, Guangzhou, Zunyi, Wuhan

2024-07-17

Recruiting

A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD)

NCT06413654Neuromyelitis Optica Spectrum Disorders

DrugB001

Shanghai Jiaolian Drug Research and Development Co., Ltd

Phase 2/3

132

Beijing, Cangzhou, Changsha, Chengdu, Fuzhou, Guangzhou, Guiyang, Hangzhou

2024-07-17

Active, closed

Open, Randomized Crossover Study on PK, PD, Biopotency, and Bioavailability of Insulin Capsules in Healthy Chinese Males

NCT06519604Diabete Mellitus

DrugHuman Insulin

Shanghai Jiao Tong University School of Medicine

Phase 1

Shanghai

2024-07-17

Recruiting

Befotertinib and Icotinib for NSCLC With Uncommon EGFR Mutations

NCT06517953Non-small Cell Lung Cancer Metastatic, EGFR G719X, EGFR L861Q, EGFR S768I

DrugsIcotinib·Befotertinib

Sun Yat-sen University

Phase 2

Guangzhou

2024-07-17

Active, closed

A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin

NCT06257966Type2 Diabetes Mellitus

DrugsExendin-4 Fc fusion protein·Dulaglutide·Metformin

Beijing Dongfang Biotech Co., Ltd.

Phase 3

600

Beijing

2024-07-17

Recruiting

Evaluating Safety, Tolerability and Pharmacokinetic of Multiple Ascending Doses of VV119

NCT06504290Schizophrenia

DrugVV119

Vigonvita Life Sciences

Phase 1

Beijing, Xi’an

2024-07-16

Recruiting

Clinical Study of mRNA Vaccine Combined With PD-1 Inhibitor as Adjuvant Therapy for Postoperative Pancreatic Cancer

NCT06496373Pancreatic Cancer Resectable, Chemotherapy-intolerant

DrugPersonalized neoantigen tumor vaccine

Ruijin Hospital

Early Phase 1

Shanghai

2024-07-16

Recruiting

Adebelimab Combined With Irinotecan Liposomal Injection, Oxaliplatin, Fluorouracil and Calcium Folinate Are Used in the First-line Treatment of Pancreatic Cancer Liver Metastasis Efficacy and Safety

NCT06531278Pancreatic Cancer Metastatic to Liver

DrugsIrinotecan liposome·Calcium folinate·Fluorouracil·Adebrelimab

Jiang Long

Phase 2

Shanghai

2024-07-16

Active, closed

Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)

NCT06456346Essential Thrombocythemia

DrugsBomedemstat·Hydroxyurea

Merck Sharp & Dohme LLC

Phase 3

300

Bengbu, Hefei, Beijing, Chongqing, Quanzhou, Xiamen, Guangzhou, Shijiazhuang

2024-07-16

Recruiting

Inhaled Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Post-Infectious Cough: A Single-Center Randomized Controlled Clinical Trial

NCT07103980Post-Infectious Cough

DrugCompound methoxyphenamine

Shanghai Changzheng Hospital

Phase 1/2

Shanghai

2024-07-16

Recruiting

Safety and Efficacy Study of NGGT002 in Adult Patients With Phenylketonuria

NCT06687733Phenylketonurias

NGGT (Suzhou) Biotechnology Co., Ltd.

Phase 1/2

Bengbu, Shanghai

2024-07-16

Recruiting

Evaluating the Usefulness of 18F-AlF-FAPI PET/ CT in Orbital Neoplasms

NCT06791226Orbital Neoplasms

Peking University Third Hospital

Not applicable

Beijing

2024-07-16

Recruiting

Choroidal and Retinal Features in PACD and POAG on OCT and OCTA

NCT07580014Glaucoma, OCTA, Choroid

Zhongshan Ophthalmic Center, Sun Yat-sen University

Observational

132

Guangzhou

2024-07-16

Recruiting

Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study

NCT06534762NSCLC, SCLC, Colorectal Cancer, Pancreas Cancer

DrugMirabegron

Zhejiang Provincial People's Hospital

Phase 2

260

Hangzhou

2024-07-15

Recruiting

Modified Aortic Root Enlargement Procedure

NCT06517537Small Aortic Annulus, Aortic Root Enlargement Procedure

China National Center for Cardiovascular Diseases

Observational

Beijing

2024-07-15

By invitation

Constructing a Risk Prediction Model for Intraoperative Hypothermia in Children Under General Anesthesia

NCT06892795Hypothermia, Accidental, Hypothermia; Anesthesia

Harbin Medical University

Observational

562

Harbin

2024-07-15

Recruiting

Ivonescimab(AK112/SMT112) in Combination With Stereotactic Body Radiation Therapy and Chemotherapy in Patients With Pancreatic Cancer

NCT06491472Pancreatic Cancer

DrugsIvonescimab·Nab-paclitaxel·Gemcitabine

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 2

Wuhan

2024-07-15

Active, closed

Clinicopathological Features and Genetic Susceptibility Screening of Recurrent Drug-induced Liver Injury

NCT06547229Recurrent Drug-induced Liver Injury

Beijing Friendship Hospital

Observational

Beijing

2024-07-15

Recruiting

Internal Mammary Lymph Nodes Irradiation in High-risk Breast Cancer After Neoadjuvant Chemotherapy

NCT06559696Breast Cancer

Fujian Medical University Union Hospital

Phase 3

722

Fuzhou

2024-07-15

Recruiting

Efficacy and Safety of Dual-targeted Therapy With Upadacitinib and Ustekinumab Versus Intensified Ustekinumab Therapy in Crohn's Disease

NCT06520397Crohn Disease

DrugUstekinumab

Sixth Affiliated Hospital, Sun Yat-sen University

Phase 4

214

Guangzhou

2024-07-15

Recruiting

Real-world Study on the Management of Hematological Toxicities Associated With Targeted Therapies for Breast Cancer

NCT06503380Hematological Toxicity, Targeted Therapy, Breast Cancer

Fudan University

Observational

1,000

Shanghai

2024-07-15

Not yet open

Prospective Observational Cohort Study

NCT06493448Gastric Cancer, Liver Metastases

Lin Chen

Observational

1,326

Beijing

2024-07-15

Not yet open

Remimazolam Besylate and Propofol Sedation on Hemodynamic for Coronary Artery Bypass Graft Patients

NCT06496165Coronary Artery Disease

DrugsRemimazolam·Propofol

Shanghai Zhongshan Hospital

Not applicable

338

Shanghai

2024-07-15

Recruiting

Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for r/m NPC

NCT06197776Multi-omics Technique, Nasopharyngeal Carcinoma, Recurrent and Metastatic Nasopharyngeal Carcinoma, Efficacy of Chemoradiotherapy and Immunotherapy

Sun Yat-sen University

Observational

Guangzhou

2024-07-15

Recruiting

Furmonertinib 160mg as First-line Treatment in Locally Advanced or Metastatic NSCLC With EGFR Classical Mutations

NCT06674343Advanced or Metastatic Non-small Cell Lung Cancer

DrugFurmonertinib

Peking Union Medical College Hospital

Phase 3

144

Beijing

2024-07-15

Not yet open

Clinical Study of Irinotecan Liposome Combination Therapy for Advanced Gastric Cancer

NCT06499610Gastric Cancer

DrugsIrinotecan Hydrochloride Liposome·Sintilimab

First Affiliated Hospital Xi'an Jiaotong University

Phase 4

Xi'an

2024-07-15

Recruiting

TGRX-678 Chinese Phase II in Chronic Myelogenous Leukemia (CML) Patients

NCT06453902Chronic Myeloid Leukemia, Accelerated Phase CML

DrugTGRX-678

Shenzhen TargetRx Co., Ltd.

Phase 2

Beijing

2024-07-15

Recruiting

SBRT and LDRT Combined With PD-1 Antibody and Chemotherapy in r/m Nasopharyngeal Carcinoma

NCT06323239Nasopharyngeal Carcinoma

DrugsToripalimab·Gemcitabine·Cisplatin

Sun Yat-sen University

Phase 2

148

Guangzhou

2024-07-15

Recruiting

Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)

NCT06511349Type 1 Primary Hyperoxaluria

DrugYOLT-203

RenJi Hospital

Early Phase 1

Shanghai

2024-07-15

Recruiting

PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer

NCT06429696Small Cell Lung Cancer Extensive Stage

DrugApatinib

Nanfang Hospital, Southern Medical University

Phase 2

Guangzhou

2024-07-14

Recruiting

The Study is an Observational Post-market Follow-up Program to Evaluate Long Term (5 Years) Safety of Mentor Breast Implants in Chinese Population

NCT06510205Breast Augmentation, Mammaplasty

Johnson & Johnson Medical (Shanghai) Ltd.

Observational

6,111

Chengdu, Kunming, Shenzhen

2024-07-14

Active, closed

Efficacy, Safety and Immunogenicity Study of Recombinant Zoster Vaccine(CHO Cell) in Adults Aged 40 Years and Older

NCT06447779Herpes Zoster

DrugRecombinant Zoster Vaccine

MAXVAX Biotechnology Limited Liability Company

Phase 3

25,000

Shijiazhuang, Zhengzhou, Wuhan, Kunming

2024-07-13

Recruiting

High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children

NCT06416488Cardiovascular Syndrome, Metabolic

Children's Hospital of Fudan University

Not applicable

336

Shanghai

2024-07-13

Recruiting

Effects of Intermittent Dietary Restriction on Cardiometabolic Risk in School-aged Children

NCT06500078Cardiovascular Syndrome, Metabolic

Children's Hospital of Fudan University

Not applicable

324

Shanghai

2024-07-13

By invitation

Study on Optimization and Evaluation of Integrated Chinese and Western Medicine for pSS Glandular Damage

NCT06519617Primary Sjögren Syndrome

DrugHydroxychloroquine Sulfate

Qingwen Tao

Phase 2

136

Beijing

2024-07-13

Recruiting

A Clinical Study of B007 in the Treatment of Pemphigus.

NCT06454357Pemphigus

DrugB007

Shanghai Jiaolian Drug Research and Development Co., Ltd

Phase 2/3

132

Beijing, Changsha, Chengdu, Chongqing, Fuzhou, Guangzhou, Jinan, Shanghai

2024-07-12

Recruiting

Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis

NCT06371040Myasthenia Gravis

Ting Chang, MD

Phase 1

Xi'an

2024-07-12

Active, closed

A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

NCT06290128Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic

DrugRiliprubart

Sanofi

Phase 3

109

Beijing, Changsha, Chengdu, Fuzhou, Guangzhou, Hangzhou, Jinan, Nanchang

2024-07-12

Active, closed

Efficacy of PD-1 Monoclonal Antibody in the Treatment of Phaeohyphomycosis

NCT06796231Phaeohyphomycosis

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Observational

Guangdong

2024-07-12

Recruiting

Predictive Value of Tumor Microenvironment PET/CT for Response and Prognosis in Aggressive Lymphoma

NCT07657494Aggressive Lymphoma

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Not applicable

Beijing

2024-07-11

Recruiting

Tirofiban for Patients With intraCranial Artery Stenosis and High-risk Acute Non-disabling Cerebrovascular Events(CHANCE-4）

NCT06319846Ischemic Stroke, Acute, TIA, Symptomatic Intracranial Artery Stenosis

DrugTirofiban

Beijing Tiantan Hospital

Phase 3

4,674

Harbin, Dezhou, Liaocheng, Yantai

2024-07-11

Active, closed

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT06445023Chronic Spontaneous Urticaria

DrugBarzolvolimab

Celldex Therapeutics

Phase 3

963

2024-07-11

Active, closed

Combination of Orelabrutinib and Obinutuzumab in Untreated Marginal Zone Lymphomas

NCT06513234Marginal Zone Lymphoma

Institute of Hematology & Blood Diseases Hospital, China

Phase 2

Tianjin

2024-07-11

Active, closed

JS001sc or JS001 Plus Chemotherapy is Indicated for Relapsed or Metastatic First-Line Non-Squamous Non Small Cell Lung Cancer（NSCLC）

NCT06505837Recurrent Metastatic Non-Squamous Non Small Cell Lung Cancer

Shanghai Junshi Bioscience Co., Ltd.

Phase 3

395

Changshang

2024-07-11

Recruiting

Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC

NCT06601309Esophageal Squamous Cell Carcinoma

DrugsSerplulimab·Paclitaxel·Cisplatin

Fujian Medical University Union Hospital

Phase 2

Fuzhou

2024-07-11

Recruiting

A Phase III Study of ESG401 for Locally Advanced or Metastatic HR+/HER2- Breast Cancer

NCT06383767Metastatic Breast Cancer

DrugsESG401·Vinorelbine

Qilu Pharmaceutical Co., Ltd.

Phase 3

378

Beijing

2024-07-11

Active, closed

Exploring the Efficacy of a Breathing Training Intervention in Patients With Emotionally Regulated Sleep Disorders

NCT07495423Sleep Disorder (Disorder), Mood Disorders

Qilu Hospital of Shandong University

Not applicable

188

Jinan

2024-07-11

Active, closed

A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males

NCT06465914Genital Wart, Penile Cancer, Anal Cancer, PIN-1

Shanghai Bovax Biotechnology Co., Ltd.

Phase 3

9,000

Nanning, Changsha, Taiyuan, Chengdu, Kunming

2024-07-11

Recruiting

Adjuvant Radiotherapy in High Risk Locally Advanced DTC

NCT06558981Thyroid Cancer

Fudan University

Phase 3

124

Shanghai

2024-07-11

Recruiting

Phase I/II Study of IPG1094 in Advanced Solid Tumors Patients

NCT06212076Solid Tumor

DrugIPG1094

Nanjing Immunophage Biotech Co., Ltd

Phase 1/2

Shanghai

2024-07-11

Recruiting

A Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer.

NCT06434610Platinum-resistant Recurrent Ovarian Cancer

DrugPaclitaxel

Shanghai Jiaolian Drug Research and Development Co., Ltd

Phase 2

Beijing, Bengbu, Changsha, Fuzhou, Guangzhou, Jinan, Kunming, Nanning

2024-07-11

Recruiting

Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis

NCT06462417Allergic Rhinitis

Zheng Liu

Not applicable

Wuhan

2024-07-11

Recruiting

Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells

NCT06420076T Cell Lymphoma, T Cell Leukemia, T-cell Acute Lymphoblastic Leukemia, T-Cell Lymphoma of CNS

Essen Biotech

Phase 1/2

Beijing

2024-07-10

Recruiting

Bendamustine and Rituximab With or Without Orelabrutinib in MCL Treatment

NCT06496308Mantle Cell Lymphoma (MCL)

DrugsOrelabrutinib·Bendamustine·Venetoclax·Rituximab

Ruijin Hospital

Phase 3

Shanghai

2024-07-10

Recruiting

Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer

NCT06791148Gastric Cancer

DrugsAlbumin-Bound Paclitaxel·Ivonescimab

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 2

Nanjing

2024-07-10

Recruiting

A Study to Evaluate Comparative Efficacy and Safety of Guselkumab in High-dose and Extended-interval Versus Standard-dose in Chinese Participants of Moderate-to-severe Plaque Psoriasis

NCT07532486Psoriasis

DrugsTremfya·Guselkumab

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

400

Hangzhou

2024-07-10

Recruiting

Multicenter Real-World Study of Hyperthermia in Warts of Special Population

NCT06827938Warts

First Hospital of China Medical University

Not applicable

400

Shenyang

2024-07-10

Recruiting

LM-108 in Combination With PD-1 Based Treatment for Patients With Recurrent or Metastatic Triple - Negative Breast Cancer

NCT06387628TNBC - Triple-Negative Breast Cancer

DrugsLM-108·Eribulin·Toripalimab·Nab-paclitaxel

Fudan University

Phase 2

Shanghai

2024-07-10

Active, closed

Brolucizumab Efficacy and Safety Single-Arm Descriptive Trial in Patients With Persistent Diabetic Macular Edema

NCT06498050Diabetic Macular Edema

Guangdong Provincial People's Hospital

Phase 4

Guangzhou

2024-07-10

Not yet open

A Phase lb/lI Clinical Study in Advanced or Metastatic Esophageal Squamous Cell Carcinoma

NCT06487702Esophageal Squamous Cell Carcinoma

DrugsCandonilimab·Tegafur, Gimeracil and Oteracil Potassium·Fruquintinib

Rui-hua Xu, MD, PhD

Phase 2

Guangzhou

2024-07-10

Recruiting

A Single-Arm, Prospective Study of TBI+BUMEL as Conditioning for SCT2 in Patients With Malignant Hematologic Diseases

NCT06548958Malignant Hematological Diseases

The First Affiliated Hospital of Soochow University

Not applicable

Suzhou

2024-07-10

Active, closed

FIH of PFBalloon for PVI

NCT07320976Paroxysmal Atrial Fibrillation

The Third People's Hospital of Chengdu

Not applicable

Chengdu

2024-07-10

Recruiting

Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML

NCT06420063AML, Acute Myeloid Leukemia, AML, Adult Recurrent, AML, Adult

Essen Biotech

Phase 1/2

Beijing

2024-07-10

Active, closed

A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM Patients

NCT06254014Type 2 Diabetes Mellitus

DrugExendin-4 Fc fusion protein

Beijing Dongfang Biotech Co., Ltd.

Phase 3

270

Beijing

2024-07-10

Recruiting

Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients

NCT06650332Metastatic HER2 Positive Gastroesophageal Junction Cancer

DrugsXelox·MFOLFOX6·Disitamab Vedotin·Cadonilimab

Zhejiang Cancer Hospital

Phase 1/2

Hangzhou

2024-07-10

Recruiting

Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma

NCT06471738Ann Arbor Stage II Follicular Lymphoma, Grade 1 Follicular Lymphoma, Ann Arbor Stage III Follicular Lymphoma, Ann Arbor Stage IV Follicular Lymphoma

DrugsZanubrutinib·Venetoclax·Rituximab

Chinese PLA General Hospital

Phase 2

Beijing

2024-07-10

Recruiting

Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL).

NCT06213636Acute Lymphoblastic Leukemia, Adult B-Cell, Acute Lymphoblastic Leukemia, in Relapse, Non-Hodgkin Lymphoma, B-cell, Diffuse Large B Cell Lymphoma

Essen Biotech

Phase 1/2

Beijing

2024-07-10

Recruiting

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

NCT06024746Heart Failure

DrugsFinerenone·Dapagliflozin

Colorado Prevention Center

Phase 3

1,500

Guangzhou, Changsha, Jinan, Shanghai, Taiyuan, Xian City, Chengdu, Tianjin

2024-07-09

Active, closed

Efficacy and Safety of Colchicine After PCI

NCT06472908Coronary Heart Disease, Percutaneous Coronary Intervention, Colchicine

DrugColchicine

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 3

8,862

Hefei, Beijing, Chongqing, Xiamen, Lanzhou, Harbin, Zhengzhou, Enshi

2024-07-09

Recruiting

A Study of GFH375 in Patients With Advanced Solid Tumors With KRAS G12D Mutations

NCT06500676KRAS G12D Mutations, Advanced Solid Tumors

DrugCetuximab

Genfleet Therapeutics (Shanghai) Inc.

Phase 1/2

407

Hefei, Beijing, Guangzhou, Nanning, Haerbin, Zhengzhou, Wuhan, Changsha

2024-07-09

Active, closed

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction

NCT06372925Plaque, Atherosclerotic

DrugsInclisiran·Atorvastatin

Novartis Pharmaceuticals

Phase 4

318

Hefei, Fuzhou, Guangzhou, Shenzhen, Zunyi, Harbin, Zhengzhou, Wuhan

2024-07-09

Recruiting

Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC

NCT06235203Recurrent Nasopharyngeal Carcinoma

Eye & ENT Hospital of Fudan University

Phase 3

154

Shanghai, Fuzhou, Nanning, Shenzhen

2024-07-09

Active, closed

Safety and Efficacy of Tocilizumab in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

NCT06452537Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

DrugsTocilizumab·Prednisone

Tianjin Medical University General Hospital

Phase 2/3

102

Hefei, Lanzhou, Shijiazhuang, Harbin, Zhenzhou, Ordos, Changzhou, Suzhou

2024-07-09

Recruiting

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 or 2 Systemic Treatment Regimens

NCT06127407Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen

DrugIvosidenib

Servier Bio-Innovation LLC

Phase 3

156

Guangzhou, Zhengzhou, Wuhan, Changsha, Shang'ai, Shanghai, Chengdu, Hangzhou

2024-07-09

Recruiting

Association Between Local Cerebral Oxygenation Monitoring and Postoperative Stroke in Carotid Endarterectomy

NCT06406842Carotid Endarterectomy, Cerebral Autoregulation

Beijing Tiantan Hospital

Not applicable

560

Beijing

2024-07-08

Recruiting

Effectiveness of Integrative Medical Treatment in Sudden Hearing Loss

NCT07235488Sudden Hearing Loss

China Medical University Hospital

Not applicable

2024-07-08

Recruiting

CMOP±R in the Treatment of Untreated Non-Hodgkin's Lymphoma

NCT06486337NHL

The First Affiliated Hospital of Soochow University

Phase 2

197

Suzhou

2024-07-08

Recruiting

Mitoxantrone Hydrochloride Liposome in Combination With Cytarabine and Venetoclax Regimen in Newly Diagnosed Elderly AML

NCT06621199Acute Myeloid Leukemia

DrugsMitoxantrone Hydrochloride Liposome·Cytarabine·Venetoclax

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-07-08

Recruiting

TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies

NCT06484816Non Small Cell Lung Cancer, Advanced Solid Tumor, Hematologic Malignancy

Shenzhen TargetRx Co., Ltd.

Phase 1

Hangzhou

2024-07-08

Recruiting

Investigating the Functional Characteristics During Wakefulness and Sleep Based on SEEG

NCT06524479Refractory Epilepsy, Sleep

Xuanwu Hospital, Beijing

Not applicable

Beijing

2024-07-08

Recruiting

Single-cell Multi-omics Analyses of OCT-diagnosed Plaque Subtypes in Coronary Artery Disease (MOOP-CAD)

NCT06489119Coronary Artery Disease

Harbin Medical University

Observational

350

Harbin, Changchun

2024-07-07

Recruiting

Natural History of Coronary Atherosclerosis

NCT06040073Coronary Artery Disease Progression, Radial Wall Strain, Atherosclerotic Lesion, Optical Coherence Tomography

China National Center for Cardiovascular Diseases

Observational

125

Beijing

2024-07-07

Not yet open

RC48 Plus AK104 as First-line Treatment for HER2-overexpressing Advanced Gastric Cancer

NCT06492317HER2-positive Gastric Cancer

DrugsDisitamab Vedotin·Cadonilimab

The First Affiliated Hospital of Zhengzhou University

Phase 2

Zhengzhou

2024-07-06

Active, closed

Paired Emotion Reading Improves Emotion Regulation in Rural Children With ACE

NCT06505629Emotion Regulation, Adverse Childhood Experience

Peking University

Not applicable

150

Beijing

2024-07-06

Recruiting

Effect of Different Cold Therapy Programs in Patients Received Total Knee Arthroplasty Operation

NCT07021287Total Knee Arthroplasty

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Not applicable

260

Yiwu

2024-07-06

By invitation

The Effects of Kefir on Pediatric Obesity

NCT06500104Obesity

China Medical University Hospital

Not applicable

2024-07-06

Recruiting

Mitoxantrone Hydrochloride Liposome, Standard-dose of Cytarabine and Venetoclax in the Treatment of R/R AML

NCT06621212Relapsed/Refractory Acute Myeloid Leukaemia, Myeloid Malignancy

DrugsMitoxantrone Hydrochloride Liposome·Cytarabine·Venetoclax

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-07-05

Recruiting

A Clinical Study Evaluating LY-M001 Injection in the Treatment of Adult Patients With Type I Gaucher Disease

NCT06818838Gaucher Disease Type 1

Lingyi Biotech Co., Ltd.

Phase 1/2

Guangzhou, Taiyuan, Tianjin

2024-07-05

Active, closed

A Study to Evaluate the Safety and Tolerability of GEN6050X in Duchenne Muscular Dystrophy.

NCT06392724Duchenne Muscular Dystrophy (DMD)

Peking Union Medical College Hospital

Early Phase 1

Beijing

2024-07-05

Active, closed

A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

NCT06385678Advanced KRAS G12D Mutant Solid Tumors

DrugsSHR-9839·HRS-4642·Adebrelimab·Cetuximab

Jiangsu HengRui Medicine Co., Ltd.

Phase 1/2

Shanghai

2024-07-05

By invitation

Safety, Tolerability, and Pharmacokinetics of FHND1002 Granules in Healthy Adults

NCT06782958Amyotrophic Lateral Sclerosis (ALS)

Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd.

Phase 1

Lanzhou

2024-07-05

Recruiting

To Explore the Efficacy of Sintilimab Combined With Bevacizumab in Rectal Cancer

NCT06808412Rcctal Cancer

DrugSintilimab

xiaohua li

Phase 2

118

Xi'an

2024-07-05

Recruiting

A Clinical Study on the Efficacy and Safety of Fasudil Hydrochloride Combined With Immunotherapy in the Treatment of Metastatic Castration-resistant Prostate Cancer

NCT07250542Prostate Cancer

DrugFasudil Hydrochloride

baotai Liang

Phase 2

Nanjing

2024-07-05

Recruiting

A Study of SKB518 in Patients With Advanced Solid Tumors

NCT06428331Advanced Solid Tumors

DrugSKB518

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Phase 1

150

Shanghai

2024-07-04

Active, closed

Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV Steroid-refractory Acute Graft vs. Host Disease

NCT06462469Steroid-refractory Acute Graft Versus Host Disease

DrugRuxolitinib

Novartis Pharmaceuticals

Phase 4

Guangzhou, Zhengzhou, Wuhan, Xian, Hangzhou, Beijing, Taian, Tianjin

2024-07-04

Recruiting

The Effect of Serum Ferritin in irAE

NCT06702566Immune-related Adverse Event, Malignant Solid Tumors, Acute Leukemia, Serum Ferritin

Tianjin Medical University Cancer Institute and Hospital

Not applicable

1,500

Tianjin

2024-07-04

Recruiting

Construction of Clinical Model of Primary Sjogren's Syndrome Combined Traditional Chinese and Western Medicine

NCT06528197Primary Sjögren Syndrome

China-Japan Friendship Hospital

Observational

1,000

Beijing

2024-07-04

Recruiting

Autologous Tumor-Infiltrating Lymphocyte (GT307) for Treatment of Patients With Solid Tumours

NCT06453057Adult

DrugGT307

Grit Biotechnology

Not applicable

Shanghai

2024-07-04

Recruiting

AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy

NCT06494995Head and Neck Squamous Cell Carcinoma

DrugsCadonilimab·Capecitabine

Fudan University

Phase 2

Shanghai

2024-07-03

Recruiting

ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study

NCT06609551Colon Cancer, Colon Cancer (Stage II &Amp;Amp;Amp; III)

Zhejiang Cancer Hospital

Phase 3

312

Hangzhou

2024-07-03

Recruiting

A Study of FZ-AD005 in Patients With Advanced Solid Tumors

NCT06424665Advanced Solid Tumor, SCLC(Small Cell Lung Cancer) or LCNEC (Large Cell Neuroendocrine Carcinoma)

DrugFZ-AD005

Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.

Phase 1

162

Changsha, Shanghai, Hangzhou

2024-07-03

Not yet open

Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage

NCT06272565Diabetic Retinopathy, Diabetic Macular Edema, Anti-vascular Endothelial Growth Factor

Zhongshan Ophthalmic Center, Sun Yat-sen University

Observational

240

Guangzhou

2024-07-03

Recruiting

Clinical Trial of VIM With VIT in Children With Relapsed and Refractory Soft Tissue Sarcoma.

NCT06514313Soft Tissue Sarcoma

DrugsMitoxantrone Hydrochloride Liposome·Temozolomide·Vincristine·Irinotecan

Yizhuo Zhang

Phase 2

110

Guangzhou

2024-07-03

Active, closed

A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R09b in Severe AADC Deficiency

NCT06432140Aromatic L-amino Acid Decarboxylase Deficiency

Shanghai Vitalgen BioPharma Co., Ltd.

Phase 2/3

Shanghai

2024-07-02

Recruiting

Olanzapine Impact on First-line Immunotherapy for Advanced EGFR-negative NSCLC

NCT06554613Non-Small Cell Lung Cancer

DrugsOlanzapine·Opdivo·Nivolumab

Second Affiliated Hospital of Nanchang University

Phase 2

156

Nanchang

2024-07-02

Recruiting

OPT-CAD Score GUIded Dual ANtiplatelet De-esCalation Time

NCT06216821Acute Coronary Syndrome

DrugStandard DAPT

Shenyang Northern Hospital

Not applicable

3,490

Shenyang

2024-07-02

Recruiting

Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML.

NCT06483906Acute Myeloid Leukemia

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Phase 2

Shanghai

2024-07-02

Recruiting

A Phase IB/II Clinical Study of SHR-9839 for Injection Combined With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors

NCT06474455Advanced Solid Tumors

DrugsAlmonertinib Mesilate·SHR-A1921·SHR-9839·SHR-A2009

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 1/2

156

Zhengzhou, Hangzhou

2024-07-02

Recruiting

Transcranial Magnetic Stimulation Synchronized with Motor Task Training for Post-Stroke Rehabilitation

NCT06849505Stroke, Upper Extremity Parasis

First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University

Not applicable

Shanghai

2024-07-02

Recruiting

Change in Serum Biomarkers After Endovascular Treatment for Acute Anterior Circulation Large Vessel Occlusion

NCT06383182Ischemic Stroke

General Hospital of Shenyang Military Region

Observational

800

Shenyang

2024-07-02

Recruiting

Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery

NCT06869096Colorectal Cancer, Surgical Site Infection, Chlorhexidine, Complications

Nanchong Central Hospital

Not applicable

532

Nanchong

2024-07-02

By invitation

Real-world Study of Acalabrutinib

NCT06767891Mantle Cell Lymphoma (MCL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Ruijin Hospital

Observational

160

Shanghai

2024-07-02

Recruiting

RW Study of Adjuvant Radiotherapy in Locally Advanced Thyroid Cancer

NCT06524167Thyroid Cancer

Fudan University

Observational

Shanghai

2024-07-02

Recruiting

Clinical Trial of CD19-targeted CAR-T Therapy for Refractory Juvenile Dermatomyositis

NCT06569472Juvenile Dermatomyositis

Chongqing Precision Biotech Co., Ltd

Phase 1

Hangzhou

2024-07-02

Recruiting

A Phase I Study of CG-7321 Monotherapy or Combination Therapy in Advanced Solid Tumors

NCT07923214Advanced Solid Tumors, Breast Cancer, Ovarian Cancer, Gastric Cancer

Chengdu Cynogen Bio-pharmaceutical Tech. Co., Ltd.

Phase 1

Fuzhou, Dalian, Shanghai, Chengdu

2024-07-02

Recruiting

Decoding the Association of Imaging and Tumor Microenvironment in Lung Cancer Using Radiogenomic Approach（Radiogenomics-Lung）

NCT06500312Lung Cancer

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

150

Wuhan

2024-07-02

Recruiting

Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia

NCT06359106Oxygenation Index

China Medical University, China

Phase 4

1,176

Shenyang, Beijing, Chendu, Chifeng, Dalian, Harbin, Jinan, Kunming

2024-07-02

Not yet open

Clinical Effectiveness of CEM in Diagnosis of Additional Findings at Preoperative Breast Magnetic Resonance Imaging

NCT06475066Breast Cancer

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Not applicable

320

Wuhan

2024-07-01

Recruiting

Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC

NCT06348927Non-Small Cell Lung Cancer

DrugsSunvozertinib·Anlotinib

Hunan Province Tumor Hospital

Phase 2

Changsha

2024-07-01

Not yet open

Catheter Ablation of Haemodynamically Not-tolerated Electrical Storm in Structural Heart Disease

NCT06455020Ventricular Tachycardia

Beijing Anzhen Hospital

Not applicable

Beijing, Changsha, Kunming, Nanjing

2024-07-01

Recruiting

Recurrent Liver Cancer: Reconceptualization and Reevaluation

NCT06430983Recurrent Liver Cancer, Primary Liver Cancer

Nanjing Medical University

Observational

300

Nanjing

2024-07-01

Recruiting

Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis

NCT06501391NSCLC Stage IV, Brain Metastases

Fudan University

Phase 2

Shanghai

2024-07-01

Recruiting

DRug-coAted Balloon Compared With cuttinG balloON in Treatment of Arteriovenous Fistula Stenosis

NCT06527963Arteriovenous Fistula, Angioplasty, Balloon, Hemodialysis Access Failure

RenJi Hospital

Observational

180

Zhengzhou, Nanjing, Shanghai

2024-07-01

Recruiting

Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.

NCT06492421Lung Cancer, Surgery, Non-small Cell Lung Cancer

Second Affiliated Hospital of Guangzhou Medical University

Phase 2

Guanzhou

2024-07-01

Recruiting

Effect of PCSK9 Inhibitors on Coronary Atherosclerotic Plaques Derived From Optical Coherence Tomography

NCT06520904Coronary Artery Disease, Optical Coherence Tomography

DrugBiweekly

First Affiliated Hospital of Xinjiang Medical University

Phase 4

396

Ürümqi

2024-07-01

Active, closed

Cadonilimab(AK104) Plus Concurrent Chemoradiotherapy in Patients With Locally Advanced, Unresectable, Stage III NSCLC

NCT06448910NSCLC, Locally Advanced Lung Carcinoma

DrugCadonilimab

Fudan University

Phase 2

Shanghai

2024-07-01

Not yet open

Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases

NCT06480630Acute Graft Versus Host Disease, Malignant Hematologic Neoplasm

DrugBasiliximab

Anhui Provincial Hospital

Phase 2

Hefei

2024-07-01

Recruiting

A Phase II Trial of Perioperative Adebrelimab Combined With XELOX in Resectable Locally Advanced Gastric/Gastroesophageal Junction Cancer (GC/GEJC)

NCT06506292Adebrelimab (SHR-1316), XELOX, GC/GEJC

DrugsXelox·Adebrelimab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-07-01

Recruiting

Neoadjuvant Adebrelimab in Resectable SCLC: A Randomized Trial

NCT06485544Small Cell Lung Cancer (SCLC)

DrugsAdebrelimab·Etoposide

Tang-Du Hospital

Phase 2

104

Xi'an

2024-07-01

Recruiting

Development and Application of an Artificial Intelligence-driven Accurate Identification Model for Gastric Cancer Lymph Node Metastasis

NCT06534814The Primary Focus of This Study is on Gastric Cancer

Hebei Medical University

Observational

300

Shijiazhuang

2024-07-01

Recruiting

Exploratory Study With Parallel Controls on the Safety and Efficacy of Neoadjuvant Low Branched-Chain Amino Acid Diet in Combination With Anti-PD-1 Monoclonal Antibody for Stage III Melanoma

NCT07586891Melanoma (Skin Cancer)

Xijing Hospital

Not applicable

Xi'an

2024-07-01

Recruiting

Mechanism and Application of DBS in the Treatment of PD

NCT06400017Parkinson's Disease and Parkinsonism

Beijing Tiantan Hospital

Not applicable

Beijing

2024-07-01

Recruiting

The Efficacy and Safety of FRD001 in Ultrasound Contrast Imaging for Malignant Ovarian Masses in Women

NCT06556342Ovary Cancer

Tongji Hospital

Not applicable

198

Wuhan

2024-07-01

Recruiting

Second Haplo-transplantation for Graft Failure

NCT06512519Graft Failure, Stem Cell Transplant Complications

Peking University People's Hospital

Not applicable

Beijing

2024-07-01

Not yet open

Efficacy, Metabolism and BMD of the 3-month TP Compared to the 1-month TP in ICPP

NCT06487143Central Precocious Puberty

DrugTriptorelin pamoate（）

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase 4

134

Guangzhou

2024-07-01

Recruiting

A Pan-cancer Screening and Diagnosis Model Based on Abdominal CT Was Established

NCT06614179Abdominal Neoplasm

Xiangdong Cheng

Observational

100,000

Hangzhou

2024-07-01

Recruiting

A Clinical Study of B007 in the Treatment of Generalized Myasthenia Gravis.

NCT06447597Generalized Myasthenia Gravis

DrugB007

Shanghai Jiaolian Drug Research and Development Co., Ltd

Phase 2/3

104

Beijing, Changchun, Changsha, Chengdu, Guangzhou, Hangzhou, Jinan, Kunming

2024-07-01

Recruiting

Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients

NCT06537557Heat Stroke

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

188

Guli, Dongyang, Hanzhou, Jinhua, Lanxi, Yiwu

2024-07-01

Recruiting

SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer

NCT06476093Non-Small-Cell Lung Cancer, Brain Metastases

DrugAnlotinib hydrochloride

The First People's Hospital of Lianyungang

Not applicable

Lianyungang

2024-07-01

Recruiting

Clinical Trial of Autologous GPC3 CAR-T Cells (CBG166) Therapy for Advanced Hepatocellular Carcinoma

NCT06461624Advanced Hepatocellular Carcinoma

Zhejiang University

Phase 1

Hangzhou

2024-07-01

Recruiting

Application of PET/MRI in the Evaluation of the Efficacy of Neoadjuvant Therapy for Locally Advanced Rectal Cancer

NCT06653452Locally Advanced Rectal Cancer (LARC)

Peking Union Medical College Hospital

Not applicable

Beijing

2024-07-01

Recruiting

Radiotherapy Followed by Chemotherapy Combined With Toripalimab in Local Advanced HR-positive,HER2-negative BC.

NCT06705127HR-positive,HER2-negative Breast Cancer

DrugsJS001·Epirubicin·Toripalimab·Nab-paclitaxel

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-07-01

Recruiting

Study of Clostridioides Difficile in Infants

NCT06788769Clostridioides Difficile Infection

Westlake University

Observational

300

Hangzhou

2024-07-01

Recruiting

TSPO-PET/MRI in Surveillance of Neuroinflammation in the Central Nervous System

NCT06467773Central Nervous System Diseases

Tongji Hospital

Observational

100

Wuhan

2024-07-01

Recruiting

Safety and Efficacy of Anti-BCMA-GPRC5D CAR-T Cells Therapy in the Treatment of r/r MM

NCT06515262Relapsed/Refractory Multiple Myeloma

920th Hospital of Joint Logistics Support Force of People's Liberation Army of China

Not applicable

Kunming

2024-07-01

Recruiting

Risk Evaluation by COronary Imaging and Artificial intelliGence Based fuNctIonal analyZing tEchniques - IV

NCT06793787Coronary Artery Disease, Coronary Atheroscleroses, Acute Coronary Syndromes (ACS), Chronic Coronary Syndrome

Ruijin Hospital

Observational

200

Shanghai

2024-07-01

Recruiting

A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT06444009Head and Neck Squamous Cell Carcinoma

DrugsPenpulimab·Cadonilimab·Ivonescimab

Lei Liu

Phase 2

Chengdu

2024-07-01

Active, closed

Preserving the Pre-cardial Fat Pad During Sleeve Gastrectomy on Postoperative Gastroesophageal Reflux

NCT06732661Sleeve Gastrectomy, Pre-cardial Fat Pad, Excessive Weight Loss, Total Weight Loss

Beijing Chao Yang Hospital

Not applicable

Beijing

2024-07-01

Active, closed

CMV-specific T Cell Immunity Test Indicated Prophylaxis of Letermovir After All-HSCT

NCT06449586Hematologic Malignancy

DrugLetermovir

Ruijin Hospital

Phase 3

250

Wuhan, Shanghai, Hangzhou

2024-07-01

Recruiting

PyroEVs/PLIN3 Mediate Lipid Droplet-Mitochondrial Coupling in Sepsis Endothelial Injury

NCT07727265Sepsis

Zhongda Hospital

Observational

180

Nanjing

2024-07-01

Recruiting

Evaluation of Perilesional Biopsy in Diagnosis of Prostate Cancer

NCT06482645Prostate Cancer

Peking University First Hospital

Not applicable

640

Beijing

2024-07-01

Recruiting

Effects of Myoelectric Biofeedback on Upper Limb Function in Post-stroke Patients

NCT06443008Biofeedback, Rehabilitation, Cerebral Infarction

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Not applicable

Yiwu

2024-07-01

Recruiting

Predictive Role of sTREM in Endovascular Thrombectomy Outcomes

NCT06545591Acute Ischemic Stroke

The Affiliated Hospital of Xuzhou Medical University

Observational

300

Xuzhou

2024-07-01

Active, closed

Effect of Glycosuria on Urinary Protein in Patients With Chronic Kidney Disease Treated With SGLT2 Inhibitors

NCT07084038Chronic Kidney Disease

Yuanjun Yang

Observational

300

Beijing

2024-07-01

Recruiting

An Observational Study on Lecanemab Treatment for Early Alzheimer's Disease

NCT07153848Alzheimer Disease

First Affiliated Hospital of Zhejiang University

Observational

400

Hangzhou

2024-07-01

Recruiting

Evaluation of Vulnerability of Carotid Plaques and Prediction of Cardio-Cerebrovascular Event Using Ultrasonic Imaging

NCT06473272Carotid Plaque, Ischemic Stroke, Cardiovascular Events

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Observational

600

Shanghai

2024-07-01

By invitation

A Multicenter, Prospective, Randomized, Controlled Study of Decitabine in Combination With R-CHOP for Initial Treatment of EBV+ Diffuse Large B-cell Lymphoma

NCT07348575Lymphoma, Large-Cell, Diffuse

DrugsR-Chop·Decitabine

Second Affiliated Hospital of Nanchang University

Phase 3

Nanchang

2024-07-01

Not yet open

LCAR-M61S and LCAR-M61D in Treatment of Relapsed/Refractory Multiple Myeloma

NCT06472479Relapsed/Refractory Multiple Myeloma

DrugsFludarabine·Cyclophosphamide

The First Affiliated Hospital with Nanjing Medical University

Not applicable

Hefei, Zhengzhou, Nanjing, Beijing

2024-07-01

Recruiting

The Safety and Performence of ShockPulse-10 in Patients with Coronary Artery Calcification

NCT06711822Coronary Arterial Disease (CAD), Calcification; Heart

Keya Medical

Not applicable

205

Beijing

2024-07-01

Recruiting

Correlation Study of Lipid Metabolites as Markers of Hepatocellular Carcinoma

NCT06623474Hepatocellular Carcinoma

Nanfang Hospital, Southern Medical University

Observational

900

Guangzhou

2024-07-01

Recruiting

Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation

NCT07777744Ventricular Tachycardia (VT), Premature Ventricular Complexes

University Hospital, Basel, Switzerland

Observational

15,000

Nanjing

2024-07-01

Recruiting

The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP

NCT06390306Chronic Myeloid Leukemia

DrugsPonatinib·Olverembatinib·Azacitidine·Venetoclax

Peking University People's Hospital

Observational

Beijing, Chengdu, Guangdong, Kunming, Nanjing, Nanning, Nanyang, Ningbo

2024-07-01

Recruiting

To Evaluate the Efficacy and Safety of Anlotinib Hydrochloride Capsule in Postoperative Non-pCR Patients With Non-small Cell Lung Cancer

NCT06352008Non-Small Cell Lung Cancer

DrugAnlotinib

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2024-07-01

Recruiting

Risk Evaluation by COronary Imaging and Artificial intelliGence Based fuNctIonal analyZing tEchniques - III

NCT06793774Coronary Artery Disease, Coronary Atheroscleroses, Acute Coronary Syndromes (ACS)

Ruijin Hospital

Observational

300

Shanghai

2024-07-01

Recruiting

Deep Cervical Lymphatlc-Venous Anastomosis Surgery for the Treatment of Alzheimer's Disease: A Pilot Study (DIVA Study)

NCT06530732Alzheimer's Disease

DrugLecanemab

Zhejiang Provincial People's Hospital

Phase 3

Hangzhou

2024-07-01

Not yet open

Accuracy Assessment of a Novel Gas Detection Approach in Dyslipidemia Diagnosis

NCT06486857Dyslipidemias, Gas Detection Method

Beijing Anzhen Hospital

Observational

1,000

Beijing

2024-07-01

By invitation

A Metabolomics-based Study to Explore the Mechanism of Remission of Metabolic Syndrome Radical Resection of Colorectal Cancer

NCT06710314Metabolomics

Dong Peng

Observational

150

Chongqing

2024-07-01

Recruiting

Use of Nafamostat Mesilate for Anticoagulation in Patients With ECMO

NCT06276010Extracorporeal Membrane Oxygenation Complication

Xiaotong Hou

Not applicable

Beijing

2024-07-01

Recruiting

Analyse of Inflammatory Activity of Sjögren's Syndrome on 68Ga-FAPI PET-CT

NCT07062523Sjogren's Syndrome

Drug68Ga-FAPI

Peking Union Medical College Hospital

Phase 1/2

Beijing

2024-07-01

By invitation

EGPSS for Weight Management in an in Vivo Human Model

NCT07186959Obesity, Mild

Liu Yan

Not applicable

Beijing

2024-07-01

Recruiting

Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR Mutant Advanced NSCLC-RW

NCT06355609Non-small Cell Lung Cancer

DrugsSunvozertinib·Anlotinib

Hunan Province Tumor Hospital

Phase 2

100

Changsha

2024-07-01

Not yet open

Effect and Safety of Huaier Granule Versus SOX Regimen in Gastric Cancer Patients

NCT05498766Gastric Cancer

DrugsTegafur, Gimeracil and Oteracil Potassium·Huaier·Oxaliplatin

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 4

702

Wuhan, Qingdao

2024-07-01

Recruiting

Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI)

NCT06195267Aortic Dissection, Systemic Inflammatory Response Syndrome, Cardiovascular Diseases (CVD)

DrugSivelestat

Nanjing Medical University

Not applicable

500

Beijing, Nanjing

2024-07-01

Recruiting

The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for Infraorbital Neuralgia

NCT06492213Infraorbital Neuralgia, Platelet-rich Plasma

Beijing Tiantan Hospital

Observational

240

Beijing

2024-07-01

Not yet open

Irinotecan Hydrochloride Liposome Combined With Capecitabine and Lenvatinib in Patients With Biliary Tract Carcinoma

NCT06463548Biliary Tract Carcinoma

DrugsIrinotecan Hydrochloride Liposome·Lenvatinib·Capecitabine

Yunpeng Liu

Not applicable

Shenyang

2024-07-01

Recruiting

Modified Second Haplo-transplantation for Graft Failure

NCT06512545Graft Failure, Stem Cell Transplant Complications

Peking University People's Hospital

Not applicable

Beijing

2024-07-01

Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT06465069Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm

DrugPembrolizumab

Eli Lilly and Company

Phase 1

460

Beijing, Guangzhou, Shanghai

2024-07-01

Recruiting

The Impact of AI Assistance on Radiologist Performance and Healthcare Costs in LDCT-Based Lung Cancer Screening

NCT06988579Lung Cancer, Artificial Intelligence (AI), Randomized Controlled Trial

The First Affiliated Hospital of Guangzhou Medical University

Not applicable

7,294

Guangzhou

2024-07-01

Not yet open

Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria

NCT06469229Hematuria, Urothelial Carcinoma, Bladder Cancer, Ureter Cancer

Changhai Hospital

Observational

1,200

Shanghai

2024-07-01

Recruiting

Segmentectomy for Solid-dominant Lung Cancer

NCT06634966Segmentectomy, Lung Adenocarcinoma

Fudan University

Phase 3

277

Shanghai

2024-07-01

Recruiting

The Clinical Application of Artificial Intelligence Assisted Renal Biopsy Diagnosis System.

NCT07330362Chronic Glomerulonephritis, Chronic Kidney Disease

Zhujiang Hospital

Observational

2,900

Guangzhou

2024-07-01

Recruiting

Outcome and Improvement of Different Treatment in Arteriosclerosis Obliterans

NCT06485622Arteriosclerosis Obliterans

First Affiliated Hospital, Sun Yat-Sen University

Observational

400

Guangzhou

2024-07-01

Recruiting

Evidence-based Evaluation and Mechanism of Shenhuang Granules in the Treatment of Sepsis

NCT06514339Sepsis

The First Affiliated Hospital of Zhejiang Chinese Medical University

Early Phase 1

410

Hangzhou

2024-07-01

Recruiting

Neoadjuvant Intra-tumor Double Immunotherapy for Hepatocellular Carcinoma.

NCT06492408Hepatic Cancer, Surgery

Second Affiliated Hospital of Guangzhou Medical University

Phase 2

Guanzhou

2024-07-01

Recruiting

FeNO Observation Study in ICU Patients With ARS

NCT06680895Compare the Concentration of Exhaled Nitric Oxide in Patients With Different Severity of RF

Shanghai Zhongshan Hospital

Observational

1,000

Shanghai

2024-07-01

Recruiting

Comprehensive Clinical Evaluation Study of GLP-1RA

NCT06686134T2DM

LI YAN

Observational

492

Jinan

2024-07-01

Not yet open

CLIF Correction VS. Conventional Correction Strategy for ASD

NCT05982808Spinal Deformity

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

420

Hangzhou

2024-07-01

Active, closed

CapeOx Combined With Anti-PD1 Antibody Plus Dihydroartemisinin as Neoadjuvant or Conversion Therapy for Microsatellite Stable Locally Advanced and Metastatic Colorectal Cancer

NCT07801352Locally Advanced Colorectal Cancer, Metastatic Colorectal Cancer

DrugsDihydroartemisinin·Tislelizumab·Capecitabine·Oxaliplatin

Shanghai Changzheng Hospital

Phase 2

Shanghai

2024-07-01

Not yet open

Predicting Adverse Kidney Events of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers

NCT06351813Acute Kidney Injury, Critical Illness, Kidney Failure

Shanghai Zhongshan Hospital

Observational

358

Shanghai

2024-07-01

Recruiting

Calcium Folinate Treatment of Spastic Paraplegia 56

NCT06478238Hereditary Spastic Paraplegia

DrugCalcium folinate

Shanghai 6th People's Hospital

Early Phase 1

Shanghai

2024-07-01

Recruiting

Deep Learning-based sbORN Diagnostic Model

NCT06463392Nasopharyngeal Carcinoma, Herpesvirus 4, Human

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Observational

312

Guangzhou

2024-07-01

Recruiting

Hypofractionated Radiotherapy Combined with Immunotherapy for Limited-stage Small-cell Lung Cancer

NCT06527898Small-cell Lung Cancer

Anhui Provincial Hospital

Phase 1/2

Hefei

2024-07-01

Active, closed

SHR-8068 in Combination With Adebrelimab, Bevacizumab, and Platinum-Based Chemotherapy as First-line Treatment in Patients With Advanced Biliary Tract Cancer

NCT06465563Biliary Tract Cancer

DrugsSHR-8068·Adebrelimab·Gemcitabine·Bevacizumab

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 2

Nanjing, Hangzhou

2024-07-01

Recruiting

Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets

NCT06959628Carotid Artery Stenosis, Carotid Artery Diseases

Shenzhen Wecan Medical Technology Co.,Ltd

Not applicable

Beijing

2024-07-01

Recruiting

Study on Clostridium Difficile Infection in Infants

NCT06703918Clostridium Difficile Infection

First People's Hospital of Hangzhou

Observational

150

Hangzhou

2024-07-01

By invitation

MRD-positive Colorectal Cancer Patients Combined With Personalized Immune Regulation Diagnosis

NCT06434376Colorectal Cancer

Second Affiliated Hospital of Wenzhou Medical University

Early Phase 1

Wenzhou

2024-07-01

Not yet open

Trametinib Plus Anlotinib Combined With Tislelizumab in KRAS-mutant NSCLC

NCT06456138KRAS Mutation-Related Tumors, Advanced Lung Cancer, Refractory Tumor

DrugsTrametinib·Anlotinib·Tislelizumab

Shanghai Chest Hospital

Phase 1/2

Shanghai

2024-07-01

Active, closed

Borderline of CME/D3 Dissection for Local Advanced Right-sided Colon Cancer

NCT06709144Colon Cancer

Haixing Ju, MD

Phase 3

896

Hangzhou

2024-07-01

Recruiting

D-TACE-HAIC Combined With Envafolimab and Lenvatinib for Unresectable ICC

NCT06643208Intrahepatic Cholangiocarcinoma

Fujian Provincial Hospital

Observational

Fuzhou

2024-07-01

Not yet open

Combining Chemoradiotherapy With Sintilimab in First-Line ICC

NCT06447454ICC

DrugsSerplulimab·Gemcitabine·Cisplatin

Shanghai Zhongshan Hospital

Observational

Shanghai

2024-07-01

Recruiting

The Efficacy and Safety of HCQ Plus TPO-RA in ANA Positive ITP

NCT06479291Immune Thrombocytopenia With Positive ANA Antibodies

DrugsEltrombopag·Hydroxychloroquine

Yunfeng Cheng

Not applicable

126

Shanghai

2024-07

Not yet open

Anlotinib Hydrochloride Capsules Combined With TQB2450 in the Treatment of Endometrial Cancer

NCT06475599Endometrial Cancer

DrugsAnlotinib hydrochloride·Benmelstobart

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 3

420

Hefei, Fuzhou, Lanzhou, Guangzhou, Huizhou, Jiangmen, Meizhou, Guigang

2024-07

Not yet open

Consolidative Radiotherapy (CSRT) in Patients With Oligometastatic/Locally Advanced Unresectable Bilary Tract Cancer (BTC)

NCT06502080Biliary Tract Cancer

Shanghai Zhongshan Hospital

Phase 2

128

Shanghai

2024-07

Recruiting

Safety and Efficacy of PRG-1801 for Refractory Lupus Nephritis and IgG4-Related Disease

NCT06497387Lupus Nephritis, IgG4-related Disease

DrugPRG-1801

Tongji Hospital

Early Phase 1

Wuhan

2024-07

Not yet open

Efficacy and Safety of Probiotics Combined With Enteric-coated Budesonide Capsules in Patients With Primary IgA Nephropathy

NCT06528015Glomerulonephritis, IGA, Probiotics, Budesonide

Gang Xu

Phase 4

206

Wuhan

2024-07

Recruiting

A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma

NCT06494371Hodgkin's Lymphoma, Anaplastic Large Cell Lymphoma

Ruijin Hospital

Phase 1

Shanghai

2024-07

Recruiting

Accuracy of LAA Occluder Size Selection: CT vs. DSA During Combined AF Ablation and LAA Occlusion

NCT06455644Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases

First Affiliated Hospital of Shantou University Medical College

Not applicable

238

Foshan, Meizhou, Shantou, Zhongshan

2024-07

Recruiting

Safety and Efficacy of PRG-2311 for Refractory Lupus Nephritis and IgG4-Related Disease

NCT06497361Lupus Nephritis, IgG4-related Disease

Tongji Hospital

Early Phase 1

Wuhan

2024-07

Not yet open

Aromatherapy in the Treatment of Early Breast Cancer

NCT06435104Early Breast Cancer

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase 2

Guangzhou

2024-07

Recruiting

Local Liver Treatment for Multi-organ Colorectal Cancer Metastases

NCT06449937Metastatic Colorectal Carcinoma, Multi-organ Metastatic Colorectal Cancer, Metastatic Malignant Neoplasm in the Liver

Anhui Provincial Hospital

Not applicable

130

Chuzhou, Fuyang, Hefei, Ma’anshan, Wuhu

2024-07

Not yet open

TQB2916 Injection Combined With Chemotherapy or Penpulimab Injection in the Treatment of Solid Tumors

NCT06500091Soft Tissue Sarcoma, Melanoma

DrugsTQB2916·Penpulimab·Doxorubicin Hydrochloride

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 2

Beijing, Zhengzhou, Changsha, Changchun, Jinan, Shanghai, Taiyuan, Tianjin

2024-07

Recruiting

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

NCT06446726Esophageal Squamous Cell Carcinoma

DrugsNab-paclitaxel·Tislelizumab·Cisplatin

Sichuan University

Phase 2

Chengdu

2024-06-30

Active, closed

A Multicenter, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, HER2-negative, Gastric or Gastroesophageal Junction Adenocarcinoma (G-HOPE-001)

NCT06238843Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

DrugsIBI343·Irinotecan·Paclitaxel

Innovent Biologics (Suzhou) Co. Ltd.

Phase 3

464

Bengbu, Hefei, Lu'an, Wuhu, Beijing, Fuzhou, Lanzhou, Dongguan

2024-06-30

Active, closed

Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors

NCT06462222Leptomeningeal Metastasis

Guangzhou Medical University

Phase 1/2

Huizhou, Beijing, Shanghai

2024-06-30

Recruiting

Guo's Aortic Arch Reconstruction: A Multicenter, Prospective Study of the Novel WeFlow-Tribranch System (GENIUS Study)

NCT06385379Aortic Arch Aneurysm

Hangzhou Endonom Medtech Co., Ltd.

Not applicable

Beijing, Changchun, Changsha, Chengdu, Guangzhou, Harbin, Jinan, Kunming

2024-06-30

By invitation

Effects of Repetitive Transcrannial Magnetic Stimulation on Non-Suicidal Self-Injury

NCT06540300NSSI

Nanjing Medical University

Not applicable

Nanjing

2024-06-30

Recruiting

Safety and Efficacy of Recombinant Human Thyroid Stimulating Hormone for Adjuvant Diagnosis in Patients With Locally Advanced/Metastatic Differentiated Thyroid Cancer

NCT06431620Recombinant Human Thyroid Stimulating Hormone

DrugRecombinant Human Thyroid Stimulating Hormone

Nanjing First Hospital, Nanjing Medical University

Not applicable

Nanjing

2024-06-30

Recruiting

A Trial on the Remission Rates of Type I Autoimmune Pancreatits With High-risk of Recurrence

NCT06468709Type 1 AIP

DrugPrednisone

Ruijin Hospital

Phase 4

Shanghai

2024-06-30

Recruiting

Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath

NCT06528418Lung Cancer, Lung Infection, COPD, Bronchitis

ChromX Health

Observational

10,000

Guangzhou

2024-06-30

Not yet open

Neoadjuvant/Adjuvant Tislelizumab Combined With Anlotinib and Platinum Doublet Chemotherapy With Resectable NSCLC

NCT06475755Non-Small Cell Lung Cancer, Anti Angiogenesis

DrugsAntiangiogenic·Pemetrexed·Tislelizumab·Paclitaxel

Tang-Du Hospital

Phase 2

178

Xi'an

2024-06-30

Recruiting

Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath

NCT06518655Pulmonary Nodules, Multiple, Pulmonary Nodules, Solitary, Lung Cancer

ChromX Health

Observational

3,000

Beijing, Foshan, Guangzhou, Wuhan, Shanghai, Chengdu

2024-06-30

Not yet open

Neoadjuvant Radiotherapy for High-risk UTUC

NCT06472752Urothelial Carcinoma of the Renal Pelvis and Ureter

Peking University First Hospital

Observational

Beijing

2024-06-30

Recruiting

Hetrombopag in Promoting Platelet Engraftment After Auto-HSCT in Children With Neuroblastoma

NCT06818916Delayed Platelet Engraftment, Neuroblastoma, Autologous Hematopoietic Stem Cell Transplantation

DrugHetrombopag

Beijing Children's Hospital

Not applicable

Beijing

2024-06-30

Active, closed

A Clinical Study Assessing the Efficacy of Chidamide for CD30-positive Peripheral T-cell Lymphoma (PTCL).

NCT06550336Peripheral T Cell Lymphoma

DrugChidamide

The First Hospital of Jilin University

Phase 2

Changchun

2024-06-30

Recruiting

Pilot Study on Evaluating the Geroprotective Effect of Metformin

NCT06459310Metformin, Aging

DrugsMetformin Hydrochloride·Metformin

Xuanwu Hospital, Beijing

Phase 2

130

Beijing

2024-06-30

Recruiting

Lymphocyte-sparing Thoracic Radiotherapy for Esophageal Squamous Cell Carcinoma

NCT06596954Esophageal Squamous Cell Cancer

Ruijin Hospital

Not applicable

212

Shanghai

2024-06-30

Active, closed

Cohort Profile：The Shandong Adenomyosis Cohort of Population Undergoing Reproductive Technology (SAart)

NCT06604091Adenomyosis, in Vitro Fertilization

The Second Hospital of Shandong University

Observational

2,241

Jinan

2024-06-30

Not yet open

Study of QLS31905 and/or QL1706 Combination With Chemotherapy in the Advanced Malignant Solid Tumors

NCT06446388Advanced Solid Tumor

DrugsQLS31905·Lenvatinib·Capecitabine·Oxaliplatin

Qilu Pharmaceutical Co., Ltd.

Phase 2

360

Beijing

2024-06-30

Recruiting

Phase II Study of Irinotecan Liposomes in First-line Treatment of Metastatic Colorectal Cancer

NCT06341296Metastatic Colorectal Cancer

DrugsIrinotecan liposome·Adrucil·Bevacizumab

West China Hospital

Phase 2

Sichuan

2024-06-30

Active, closed

A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

NCT06015737Cutaneous Lupus Erythematosus

AstraZeneca

Phase 3

339

Changchun, Changsha, Chengdu, Chongqing, Dongguan, Guangzhou, Heilongjiang, Jinan

2024-06-29

Active, closed

Umbilical Cord-derived Mesenchymal Stem Cell Exosomes on Hair Growth in Patients With Androgenetic Alopecia

NCT06697080Androgenic Alopecia

Nanfang Hospital, Southern Medical University

Not applicable

Guangzhou

2024-06-28

Recruiting

Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

NCT06458595Age-related Macular Degeneration

DrugKH658

Chengdu Origen Biotechnology Co., Ltd.

Phase 1/2

Tianjin

2024-06-28

Recruiting

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

NCT06324357Metastatic Breast Cancer, Metastatic Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Esophageal Adenocarcinoma

DrugsZongertinib·Zanidatamab·Trastuzumab emtansine·MFOLFOX6

Boehringer Ingelheim

Phase 1/2

910

Changchun, Hangzhou, Harbin, Nanjing, Shanghai, Tianjin, Zhengzhou

2024-06-28

Recruiting

Autologous Tumor-Infiltrating Lymphocyte (GT307) for Treatment of Patients With Advanced Colorectal Cancer

NCT06819280Adult

DrugGT307

Grit Biotechnology

Not applicable

Shanghai

2024-06-28

Recruiting

Optimize Study - Orelabrutinib Combined With BR/G in Untreated Marginal Zone Lymphoma (MZL)

NCT06504940Marginal Zone Lymphoma

DrugsOrelabrutinib·Obinutuzumab

First Affiliated Hospital of Zhejiang University

Phase 2

Hangzhou

2024-06-28

Recruiting

A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's Arteritis

NCT06498089Takayasu Arteritis

DrugsTofacitinib·Adalimumab·Tocilizumab·Methotrexate

Shanghai Zhongshan Hospital

Phase 4

124

Shanghai

2024-06-28

Recruiting

Prospective Cohort Study of Patients With Early Alzheimer's Disease Treated With Lecanemab

NCT06741553Alzheimer Disease, Mild Cognitive Impairment (MCI)

DrugLecanemab

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

120

Hangzhou

2024-06-28

Recruiting

Efficacy and Safety of Telitacicept for Prevention of Flares in SLE Patients

NCT06394063Systemic Lupus Erythematosus

DrugTelitacicept

RenJi Hospital

Not applicable

176

Shanghai

2024-06-28

Recruiting

A Study of BL-B16D1 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

NCT06469008Head and Neck Squamous Cell Carcinomas, Solid Tumor

DrugBL-B16D1

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Shanghai

2024-06-27

Recruiting

An Exploratory Clinical Study of CD19 CAR NK Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

NCT06464679Autoimmune Diseases

Changhai Hospital

Phase 1

Shanghai

2024-06-27

Recruiting

Effects of Remote Ischemic Preconditioning on Peripheral Blood Biomarkers in Healthy Adults (EMINENT)

NCT05957523Ischemic Preconditioning

First Affiliated Hospital Xi'an Jiaotong University

Not applicable

Xi'an

2024-06-27

Recruiting

Efficacy of Hi-tACS for Schizophrenia Negative Symptoms

NCT06888726Schizophrenia; Negative Type, Transcranial Alternating Current Stimulation

Shanghai Mental Health Center

Not applicable

Shanghai

2024-06-27

Recruiting

A Clinical Study of TQB3107 Tablets in Patients With Malignant Tumors

NCT06413953Advanced Cancers

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 1

140

Guangzhou, Zhuhai, Chengde, Harbin, Changsha, Changzhou, Binzhou, Shanghai

2024-06-27

Recruiting

Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-2)

NCT05224960Decompensated Cirrhosis

DrugUC-MSCs

Beijing 302 Hospital

Phase 2

140

Lanzhou, Guangzhou, Sanya, Wuhan, Shanghai, Kashgar, Beijing

2024-06-27

Recruiting

A Study of HS-10504 in Patients With Advanced or Metastatic Non-Small-Cell Lung Cancer(NSCLC)

NCT06461156Locally Advanced or Metastatic NSCLC

DrugHS-10504

Jiangsu Hansoh Pharmaceutical Co., Ltd.

Phase 1

230

Guangzhou

2024-06-26

Recruiting

A Trial of SHR-4849 in Advanced Solid Tumors

NCT06443489Advanced Solid Tumors

DrugSHR-4849

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 1

Jilin City

2024-06-26

Recruiting

Induction IBI110 and Sintilimab with Chemotherapy in LA HNSCC

NCT06494943Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma

DrugsCis-platinum·Sintilimab·Paclitaxel

Fudan University

Phase 1/2

Shanghai

2024-06-26

Recruiting

Effectiveness of Risk-based Sequential Screening for Esophageal and Gastric Cancer

NCT06306755Esophageal Cancer, Gastric Cancer, Precision Screening, Sequential Screening

Peking University Cancer Hospital & Institute

Not applicable

21,000

Beijing

2024-06-25

Recruiting

Adjuvant vs Surgery Only in Early-stage Recurrent NPC

NCT06228079Recurrent Nasopharyngeal Carcinoma

Eye & ENT Hospital of Fudan University

Phase 3

176

Shanghai, Fuzhou, Nanning, Shenzhen

2024-06-25

Recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors

NCT06475300Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma, Solid Tumor

DrugsIza-bren·Pemetrexed

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 2

570

Guangzhou

2024-06-25

Recruiting

Personalized Interventions Via Health Portraits in Mild Behavioral Impairment

NCT06416514Neurocognitive Disorders

Fujian Provincial Hospital

Not applicable

Fuzhou

2024-06-25

Recruiting

Phase I Study of HSK42360 in Solid Tumors With BRAF V600 Mutation

NCT06536400Solid Tumors

DrugHSK42360

Haisco Pharmaceutical Group Co., Ltd.

Phase 1

316

Beijing, Fuzhou, Guangzhou, Nanning, Zhengzhou, Changsha, Nanjing, Shanghai

2024-06-25

Recruiting

Intraventricular Administration of Intracranial Infections Caused by （Carbapenem-resistant Gram-negative Bacilli）CRGNB

NCT06595979Intracranial Infections

DrugPolymyxin B

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

222

Hangzhou, Ningbo, Wenzhou

2024-06-25

Recruiting

18F-FAPIBiotin PET/CT: Dosimetry and Biodistribution Study

NCT06734572Malignant Neoplasm

First Affiliated Hospital of Fujian Medical University

Early Phase 1

Fuzhou

2024-06-25

Recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

NCT06463587Generalized Myasthenia Gravis

DrugCladribine

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Phase 3

264

Anhui Sheng, Beijing, Guangzhou, Zunyi, Shijiazhuang, Zhengzhou, Changsha, Wuhan

2024-06-25

Recruiting

Autologous Hematopoietic Stem Cell Transplantation Combined With CD19-CART Treatment of Adult High-risk Acute Lymphoblastic Leukemia

NCT06608342Acute Lymphoblastic Leukemia ALL

Institute of Hematology & Blood Diseases Hospital, China

Phase 2

Tianjin

2024-06-25

Recruiting

Early Intervention Strategies for Lung Cancer

NCT06988943Respiratory Tract Neoplasms, Thoracic Neoplasms, Neoplasms by Site, Neoplasms

The First Affiliated Hospital of Guangzhou Medical University

Not applicable

16,000

Guangzhou

2024-06-25

Recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

NCT06465810Transthyretin Amyloidosis, ATTR-CM, ATTRv-PN, ATTR

AstraZeneca

Observational

1,850

Hefei, Beijing, Chongqing, Fuzhou, Xiamen, Guangzhou, Guiyang, Shijiazhuang

2024-06-25

Recruiting

Evaluate LAE102 in Healthy and Overweight/Obese Subjects

NCT06493084Overweight and Obese Volunteers

DrugLAE102

Laekna Limited

Phase 1

160

Shanghai

2024-06-25

Active, closed

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

NCT06118281Cardiovascular Risk, Acute Myocardial Infarction (AMI)

DrugZiltivekimab

Novo Nordisk A/S

Phase 3

10,000

Beijing, Chongqing, Fuzhou, Guangzhou, Nanning, Cangzhou, Shijiazhuang, Harbin

2024-06-25

Recruiting

A Trial to Evaluate the Effect of Applying Leukapheresis to Enrich CTCs in mPCa Patients

NCT06469710Prostate Cancer, Circulating Tumor Cell, Leukapheresis

RenJi Hospital

Observational

Shanghai

2024-06-25

Recruiting

Thrombectomy Versus Best Medical Management in Large Vessel Occlusion Stroke Patients Presenting Beyond 24 Hours and With Presence of Collateral Flow on CT Angiography

NCT06654375Stroke Acute, Thrombectomy, Medical Treatment, Large Vessel Occlusion

Tianjin Huanhu Hospital

Not applicable

350

Tianjin

2024-06-25

Recruiting

Efficacy and Safety Study of 610 in Patients With Severe Asthma

NCT06323213Asthma

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

Phase 3

480

Shanghai

2024-06-24

Recruiting

Delayed Systemic Therapy Following Destructive Local Treatment of Pulmonary Oligometastases After No Evidence of Disease (NED) in Colorectal Cancer.

NCT06778382Colorectal Neoplasms Malignant

Shandong Cancer Hospital and Institute

Phase 2

Jinan

2024-06-24

Recruiting

A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors

NCT06307795Locally Advanced or Metastatic Solid Tumors

DrugANS014004

Avistone Biotechnology Co., Ltd.

Phase 1

Beijing, Harbin, Zhengzhou, Jinan, Shanghai

2024-06-24

Active, closed

LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma.

NCT06351020Locally Advanced or Metastatic GC and GCJ Adenocarcinoma

DrugsLM-302·Apatinib·Irinotecan

LaNova Medicines Zhejiang Co., Ltd.

Phase 3

387

Beijing, Shanghai

2024-06-24

Recruiting

Prospective Clinical Study of Orelabrutinib in Combination With Rituximab (OR) for Primary Marginal Zone Lymphoma (MZL) That Failed or Not Suitable for Local Therapy

NCT06478472Marginal Zone Lymphoma

DrugsOrelabrutinib·Rituximab

The First Affiliated Hospital of Xiamen University

Not applicable

Xiamen

2024-06-23

Active, closed

SIM0718 Treatment of Asthma Clinical Study

NCT06488755Asthma; Eosinophilic

Simcere Pharmaceutical Co., Ltd

Phase 3

418

Beijing

2024-06-23

Recruiting

Liposomal Irinotecan + Oxaliplatin + Bevacizumab Versus Liposomal Irinotecan + 5-FU/LV

NCT06782685Advanced Pancreatic Cancer (Part 1)

DrugsIrinotecan Liposomal·Adrucil·Oxaliplatin·Bevacizumab

Dai, Guanghai

Phase 1/2

138

Beijing

2024-06-23

Recruiting

Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock

NCT06481410Septic Shock, Methylene Blue, Sepsis

First Affiliated Hospital of Zhejiang University

Not applicable

488

Hangzhou

2024-06-22

Recruiting

Neoadjuvant Envafolimab Plus Disitamab Vedotin and Carboplatin in Resectable HER2-Mutant Non-Small-Cell Lung Cancer

NCT06734182Non-small Cell Lung Cancer

DrugsEnvafolimab·Disitamab Vedotin·Carboplatin

Guangdong Provincial People's Hospital

Phase 2

Guangzhou

2024-06-22

Active, closed

A Study of LVGN6051 Combination Therapy in Patient With Head and Neck Squamous Cell Carcinoma (HNSCC)

NCT06378177Head and Neck Squamous Cell Carcinoma

DrugsToripalimab·Paclitaxel

Lyvgen Biopharma Holdings Limited

Phase 2

Hefei, Beijing, Fuzhou, Guangzhou, Nanning, Zhengzhou, Wuhan, Changsha

2024-06-21

Recruiting

An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy

NCT06469190Nephropathy

Changhai Hospital

Early Phase 1

Shanghai

2024-06-21

By invitation

A Clinical Study to Evaluate CUD005 Injection in Patients with Liver Cirrhosis

NCT06671275Cirrhosis Liver

Anhui Provincial Hospital

Phase 1

Hefei

2024-06-21

Recruiting

Risk Factors of Anxiety and Depression in Patients With Herpes Zoster Neuralgia

NCT06449547Herpes Zoster

Huazhong University of Science and Technology

Observational

600

Wuhan

2024-06-21

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site. Derived from ClinicalTrials.gov. Retrieved 7 November 2026. https://priyalifescience.com/clinical-trials-china?page=26

Query this register directly

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,187 studies in total at the last sync on 07 Nov 2026, 03:17 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in China?

11,790 of the 19,187 studies in this register are recruiting new participants as of the 07 Nov 2026, 03:17 UTC sync. A further 3,998 have not yet opened recruitment, 2,715 are active but closed to new participants, and 684 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (423) Advanced Solid Tumors (187) Colorectal Cancer (179) Gastric Cancer (175) Hepatocellular Carcinoma (154) Advanced Solid Tumor (153) Non-Small Cell Lung Cancer (145) Solid Tumor (142) Acute Ischemic Stroke (140) Lung Cancer (135) Non-small Cell Lung Cancer (132) Pancreatic Cancer (131) Multiple Myeloma (128) Coronary Artery Disease (122) Prostate Cancer (110)

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Browse trials by site location

Beijing (5576) Shanghai (3879) Guangzhou (3345) Hangzhou (1819) Wuhan (1343) Chengdu (1307) Nanjing (1211) Changsha (1154) Chongqing (1078) Fuzhou (1040) Tianjin (934) Zhengzhou (931) Hefei (896) Jinan (783) Changchun (639)

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.