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Compound · clinical trials

Anlotinib hydrochloride clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 15 trials in our China register that name Anlotinib hydrochloride as an intervention. Synced 25 Sep 2026
15Current trials
10Recruiting now
10Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Anlotinib hydrochloride is named as an intervention in 15 current clinical trials in our China register. 10 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Chia Tai Tianqing Pharmaceutical Group Co., Ltd (6). The most-studied condition is DTC - Differentiated Thyroid Cancer.

Trials by status

  • Recruiting1067%
  • Not yet open213%
  • Active, closed320%

Trials by phase

  • Phase 2853%
  • Phase 3320%
  • Observational17%
  • Phase 417%
  • Phase EARLY_PHASE117%
  • Not applicable17%
01

Clinical trials of Anlotinib hydrochloride

15 trials
StudyPhaseStatusLead sponsorRegisters
Exploratory Study on the Safety and Efficacy of Disitamab Vedotin in Combination with Anlotinib Hydrochloride for the Treatment of HER-2-expressing Recurrent Platinum-resistant Ovarian Cancer.
NCT06660511 · ClinicalTrials.gov ↗ · Ovarian Cancer Recurrent
Phase EARLY_PHASE1 Recruiting Second Xiangya Hospital of Central South University China
Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma
NCT05830500 · ClinicalTrials.gov ↗ · Medullary Thyroid Cancer
Phase 4 Recruiting Chia Tai Tianqing Pharmaceutical Group Co., Ltd. China
Clinical Trial Comparing TQB2868 Injection Combined With Anlotinib Hydrochloride Capsules With Placebo Combined With Chemotherapy as First-line Treatment for Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)
NCT07165951 · ClinicalTrials.gov ↗ · Metastatic Pancreatic Ductal Adenocarcinoma
Phase 3 Recruiting Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. China
Preoperative IMRT With Anlotinib and Penpulimab for Localized Sarcoma ๏ผˆSPARE-01๏ผ‰
NCT05167994 · ClinicalTrials.gov ↗ · Sarcoma,Soft Tissue, Extremity, Trunk
Phase 2 Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients
NCT05252078 · ClinicalTrials.gov ↗ · Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Esophageal Diseases
Phase 2 Recruiting Jiangxi Provincial Cancer Hospital China
XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma
NCT05494060 · ClinicalTrials.gov ↗ · Carcinoma, Gastrointestinal Diseases, Stomach Cancer
Phase 2 Recruiting The First Affiliated Hospital with Nanjing Medical University China
A Clinical Study of TQB2450 Injection Combined With Chemotherapy or Anlotinib Hydrochloride Capsule in the Treatment of Non Small Cell Lung Cancer
NCT05913089 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Phase 2 Recruiting Chia Tai Tianqing Pharmaceutical Group Co., Ltd. China
Clinical Trials of Benmelstobart Injection Combined With Anlotinib Hydrochloride Capsules in the Treatment of Advanced or Unresectable Alveolar Soft Part Sarcoma
NCT07548177 · ClinicalTrials.gov ↗ · Alveolar Soft Part Sarcoma
Phase 2 Recruiting Chia Tai Tianqing Pharmaceutical Group Co., Ltd. China
Study of Anlotinib Hydrochloride Capsules in the Treatment of Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Carcinoma
NCT05994365 · ClinicalTrials.gov ↗ · Thyroid Neoplasms
Observational Recruiting Chia Tai Tianqing Pharmaceutical Group Co., Ltd. China
SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer
NCT06476093 · ClinicalTrials.gov ↗ · Non-Small-Cell Lung Cancer, Brain Metastases
Not applicable Recruiting The First People's Hospital of Lianyungang China
Anlotinib Hydrochloride Capsules Combined With TQB2450 in the Treatment of Endometrial Cancer
NCT06475599 · ClinicalTrials.gov ↗ · Endometrial Cancer
Phase 3 Not yet open Chia Tai Tianqing Pharmaceutical Group Co., Ltd. China
Anlotinib + Benmelstobart vs Surgery for Patients With Localized Renal Cell Carcinoma Scheduled to Undergo Partial Nephrectomy
NCT07627464 · ClinicalTrials.gov ↗ · Renal Cell Carcinoma (RCC)
Phase 2 Not yet open Tianjin Medical University Cancer Institute and Hospital China
A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)
NCT04344158 · ClinicalTrials.gov ↗ · Advanced Hepatocellular Carcinoma (HCC)
Phase 3 Active, closed Chia Tai Tianqing Pharmaceutical Group Co., Ltd. China
Newly Diagnosed Glioblastoma
NCT04959500 · ClinicalTrials.gov ↗ · Glioblastoma
Phase 2 Active, closed Sun Yat-sen University China
Study on the Treatment of Differentiated Thyroid Carcinoma with Anlotinib
NCT05007093 · ClinicalTrials.gov ↗ · DTC - Differentiated Thyroid Cancer
Phase 2 Active, closed Yansong Lin China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Anlotinib hydrochloride

25 conditions
DTC - Differentiated Thyroid Cancer1Renal Cell Carcinoma (RCC)1Esophageal Squamous Cell Carcinoma1Esophageal Neoplasms1Esophageal Diseases1Gastrointestinal Neoplasms1Sarcoma,Soft Tissue1Extremity1Trunk1Anlotinib1Thyroid Neoplasms1Non Small Cell Lung Cancer1
All 25 conditions
Condition (as registered)Trials
DTC - Differentiated Thyroid Cancer1
Renal Cell Carcinoma (RCC)1
Esophageal Squamous Cell Carcinoma1
Esophageal Neoplasms1
Esophageal Diseases1
Gastrointestinal Neoplasms1
Sarcoma,Soft Tissue1
Extremity1
Trunk1
Anlotinib1
Thyroid Neoplasms1
Non Small Cell Lung Cancer1
Carcinoma1
Gastrointestinal Diseases1
Stomach Cancer1
Gastroesophageal-junction Cancer1
Alveolar Soft Part Sarcoma1
Medullary Thyroid Cancer1
Ovarian Cancer Recurrent1
Advanced Hepatocellular Carcinoma (HCC)1
Non-Small-Cell Lung Cancer1
Brain Metastases1
Metastatic Pancreatic Ductal Adenocarcinoma1
Endometrial Cancer1
Glioblastoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.6
Yansong Lin1
Tianjin Medical University Cancer Institute and Hospital1
Jiangxi Provincial Cancer Hospital1
Cancer Institute and Hospital, Chinese Academy of Medical Sciences1
The First Affiliated Hospital with Nanjing Medical University1
Second Xiangya Hospital of Central South University1
The First People's Hospital of Lianyungang1
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.1
Sun Yat-sen University1
04

By country register

RegisterTrialsRecruiting
Clinical trials in China1510

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Anlotinib hydrochloride trials

How many clinical trials are testing Anlotinib hydrochloride?

15 current trials in our China register name Anlotinib hydrochloride as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Anlotinib hydrochloride trials recruiting patients?

Yes. 10 of the 15 trials are recruiting: 10 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Anlotinib hydrochloride clinical trials?

Chia Tai Tianqing Pharmaceutical Group Co., Ltd (6), Yansong Lin (1), Tianjin Medical University Cancer Institute and Hospital (1) and Jiangxi Provincial Cancer Hospital (1), among 10 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Anlotinib hydrochloride works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Anlotinib hydrochloride works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Anlotinib hydrochloride (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.