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Priya Life Science Compound trial record
Compound · clinical trials

SI-B001 clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 10 trials in our China register that name SI-B001 as an intervention. Synced 9 Nov 2026
10Current trials
0Recruiting now
1Lead sponsor
1Country register
At a glance

SI-B001 is named as an intervention in 10 current clinical trials in our China register. None are recruiting at the moment. The most common phase is Phase 2. The lead sponsor is Sichuan Baili Pharmaceutical Co., Ltd. The most-studied condition is Head and Neck Squamous Cell Carcinoma.

How SI-B001 works

All drug targets →
Diseases it has been tested for in clinical trials, by furthest phase
  • Non-small cell lung adenocarcinomaPhase 3
  • Squamous cell lung carcinomaPhase 3
  • Non-small cell lung carcinomaPhase 2/3
  • Colorectal cancerPhase 2
  • Esophageal squamous cell carcinomaPhase 2
  • Gastric cancerPhase 2
  • Head and neck squamous cell carcinomaPhase 2

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL5095384, CC BY-SA 3.0. The Guide to Pharmacology has no record of this medicine, so its targets rest on ChEMBL alone. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for SI-B001

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Active, closed10100%

Trials by phase

  • Phase 2550%
  • Phase 1/2220%
  • Phase 3110%
  • Phase 2/3110%
  • Phase 1110%
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Clinical trials of SI-B001

10 trials
StudyPhaseStatusLead sponsorRegisters
A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma
NCT05943795 · ClinicalTrials.gov ↗ · Non-small Cell Lung Adenocarcinoma, Squamous Cell Carcinoma of Lung
Phase 3 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
SI-B001 Combined With Osimertinib Mesylate Tablets in the Treatment of Recurrent Metastatic Non-small Cell Lung Cancer.
NCT05020769 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2/3 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC.
NCT05020457 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Phase 2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma.
NCT05022654 · ClinicalTrials.gov ↗ · Esophageal Squamous Cell Carcinomas
Phase 2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
A Clinical Study to Evaluate the Efficacy and Safety of SI-B001 in the Treatment of Recurrent and Metastatic HNSCC
NCT05044897 · ClinicalTrials.gov ↗ · Head and Neck Squamous Cell Carcinoma
Phase 2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
A Clinical Study of SI-B001 in Combination With Paclitaxel/Docetaxel in the Treatment of Recurrent and Metastatic HNSCC
NCT05054439 · ClinicalTrials.gov ↗ · Head and Neck Squamous Cell Carcinoma
Phase 2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
A Study of SI-B001+SI-B003 Combined With Platinum-based Chemotherapy as First-line Treatment in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
NCT06668961 · ClinicalTrials.gov ↗ · Head and Neck Squamous Cell Carcinoma
Phase 2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma
NCT05668858 · ClinicalTrials.gov ↗ · Squamous Cell Carcinoma of Head and Neck
Phase 1/2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
A Study of SI-B001+SI-B003± Chemotherapy in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer
NCT05949606 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 1/2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China
A Study of SI-B001, an EGFR/HER3 Bispecific Antibody, in Locally Advanced or Metastatic Epithelial Tumors
NCT04603287 · ClinicalTrials.gov ↗ · Locally Advanced or Metastatic Epithelial Tumor
Phase 1 Active, closed Sichuan Baili Pharmaceutical Co., Ltd China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with SI-B001

8 conditions
Head and Neck Squamous Cell Carcinoma3Non-small Cell Lung Cancer2Non-small Cell Lung Adenocarcinoma1Squamous Cell Carcinoma of Lung1Locally Advanced or Metastatic Epithelial Tumor1Squamous Cell Carcinoma of Head and Neck1Esophageal Squamous Cell Carcinomas1Non Small Cell Lung Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Sichuan Baili Pharmaceutical Co., Ltd10
04

By country register

RegisterTrialsRecruiting
Clinical trials in China100

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about SI-B001 trials

How many clinical trials are testing SI-B001?

10 current trials in our China register name SI-B001 as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are SI-B001 trials recruiting patients?

Not at the moment. None of the 10 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.

Who sponsors SI-B001 clinical trials?

The lead sponsor is Sichuan Baili Pharmaceutical Co., Ltd. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how SI-B001 works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how SI-B001 works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists SI-B001 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.