Clinical trial register · China

Clinical Trials in China

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 19187 matching records held by the registry are in this view. Synced 07 Nov 2026, 03:17 UTC

19187

Studies in scope

all four open statuses

11790

Recruiting now

open to new participants

2028

Lead sponsors

across recruiting studies

Top sites

Beijing 5576 Shanghai 3879 Guangzhou 3345 Hangzhou 1819 Wuhan 1343

Trials in this register

Status

Study

Lead sponsor

Phase

Enrol

Chinese sites

Start

Recruiting

HRS 4642 Injection Combined With AG Versus Placebo Combined With AG Therapy in First-Line Advanced or Metastatic Pancreatic Cancer

NCT07232875KRAS G12D-Mutant Advanced or Metastatic Pancreatic Cancer in the First-line Setting

DrugHRS-4642

Jiangsu HengRui Medicine Co., Ltd.

Phase 3

588

Shanghai

2025-11-21

Recruiting

A Study of GensSci098 in Subjects With Graves' Disease

NCT07286656Safety, Tolerability, GenSci098, Graves Disease

DrugGenSci098

Changchun GeneScience Pharmaceutical Co., Ltd.

Phase 1

Shenyang

2025-11-21

Recruiting

Enteral Supplementation With Sodium Dihydrogen Phosphate and Disodium Hydrogen Phosphate Granules for the Treatment of Hypophosphatemia.

NCT07233889Hypophosphatemia

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Not applicable

Wuhan

2025-11-21

Recruiting

A Phase III Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of Plonmarlimab in Subjects With Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic Lymphohistiocytosis (Also Known as Macrophage Activation Syndrome [MAS])

NCT07208058Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic Lymphohistiocytosis

DrugPlonmarlimab

TJ Biopharma Co., Ltd.

Phase 3

Beijing, Guangzhou, Nanning, Shijiazhuang, Zhengzhou, Wuhan, Nanchang, Shenyang

2025-11-21

Recruiting

Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules

NCT07232433Lung Cancer

Ruijin Hospital

Not applicable

Shanghai

2025-11-21

Active, closed

Phase IIIb Clinical Trial of Quadrivalent Recombinant Human Papillomavirus Vaccine (Hansenulapolymorpha) for Age/Immunization Schedule Bridging

NCT06632912Human Papillomavirus (HPV) Infection, HPV (Human Papillomavirus)-Associated Carcinoma

National Vaccine and Serum Institute, China

Phase 3

1,800

Heze, Liaocheng, Tai’an

2025-11-21

Recruiting

Application of Zanubrutinib-based Combination Regimens in the Treatment of Newly-diagnosed Diffuse Large B-cell Lymphoma

NCT07371923Diffuse Large B Cell Lymphoma (DLBCL)

DrugsPola-R-Chp·Zanubrutinib

Beijing Tongren Hospital

Phase 2

Beijing

2025-11-20

Not yet open

Effectiveness of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitor Initiation Before Percutaneous Coronary Intervention on Acute Myocardial Infarction Patients

NCT06683131Acute Myocardial Infarction (AMI)

DrugTafolecimab

The Affiliated Hospital of Xuzhou Medical University

Phase 4

1,160

Fuyang, Huai'an, Lianyungang, Nanjing, Suqian, Xuzhou, Beijing, Shanghai

2025-11-20

Recruiting

A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema

NCT07216027Atopic Dermatitis, Eczema, Atopic

Pfizer

Phase 2

165

Fuzhou, Guangzhou, Shanghai, Beijing

2025-11-20

Recruiting

Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients

NCT07252102Liver Cirrhosis, Polyps of Colon, Gastrointestinal Dysfunction

Zhejiang University

Not applicable

450

Shenzhen, Hangzhou

2025-11-20

Recruiting

AI-assisted Endoscopic Ultrasound Grading of Early Esophageal Cancer Invasion Depth: A Multicenter, Prospective, Randomized Cohort Study

NCT07251114Esophageal Cancer Stage, Early Esophageal Cancer

Fujian Provincial Hospital

Not applicable

200

Fuzhou, Putian

2025-11-20

By invitation

Traditional Exercise RCT in Visually Impaired Adults

NCT07265024Visual Impairments

Northeast Normal University

Not applicable

Changchun

2025-11-20

Recruiting

40.2Gy Versus 49.2Gy Radiotherapy in Low-Risk Target Volume for Chemosensitive Stage II Nasopharyngeal Carcinoma

NCT07328854Nasopharyngeal Carcinoma

Ming-Yuan Chen

Phase 3

346

Hefei, Fuzhou, Guangzhou, Shantou, Zhongshan, Zhuhai, Nanning, Wuzhou

2025-11-20

Not yet open

Tegoprazan Plus Amoxicillin BID vs TID Regimens for H. Pylori Eradication（Frequency Adjusted Same-dose Therapy for H. Pylori）

NCT07242443HELICOBACTER PYLORI INFECTIONS

DrugsTegoprazan·Amoxicillin

First People's Hospital of Hangzhou

Phase 4

240

Hangzhou

2025-11-20

Recruiting

A Phase I/II Clinical Study of WJ22096 Tablets in Patients With Advanced Tumors

NCT07253116Advanced Solid Tumors

Nanjing Jingao biomidical technology Co. Ltd.

Phase 1/2

Beijing

2025-11-20

Not yet open

Perirenal Adipose Tissue Modification Therapy for Resistant Hypertension

NCT07232966Resistant Hypertension

Yan Li

Phase 3

220

Shanghai

2025-11-20

Recruiting

Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC)

NCT07241793Urothelial Carcinoma, Advanced Urothelial Carcinoma, Urothelial Carcinoma Recurrent

DrugsTrastuzumab Rezetecan·Adebrelimab

Sun Yat-sen University

Phase 2

Guangzhou, Wuhan, Nanchang, Kunming

2025-11-20

Recruiting

A Study of SHR-4610 Injection in Patients With Advanced Solid Tumors

NCT07231211Solid Tumors

DrugsSHR-4610·Trastuzumab Rezetecan

Shanghai Shengdi Pharmaceutical Co., Ltd

Phase 1/2

258

Hangzhou

2025-11-20

Recruiting

The Feasibility Study of Polymer Artificial Heart Valve for the Treatment the Mitral Valve Disease.

NCT07243184Severe Mitral Valve Regurgitation, Severe Mitral Valve Stenosis

Shanghai HeartEpoch Medical Technology Co., Ltd

Not applicable

Beijing

2025-11-19

Recruiting

Neuroendoscopy-assisted Drainage Versus Burr Hole Drainage for Chronic Subdural Hematoma

NCT07144423Chronic Subdural Hematoma

Beijing Tiantan Hospital

Not applicable

770

Beijing, Xiamen, Jiangmen, Shantou, Shenzhen, Liuzhou, Nanning, Wuzhou

2025-11-19

Active, closed

Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) China Study

NCT07216976Parkinson's Disease

MedtronicNeuro

Not applicable

Beijing, Guangzhou, Shanghai, Chengdu

2025-11-19

Recruiting

Prospective Cohort Control Study on Changes in Gut Microbiota in Ischemic Stroke

NCT07247838Ischemic Stroke

Affiliated Hospital of Nantong University

Observational

200

Nantong

2025-11-19

Recruiting

CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS

NCT07612774Coronary, Coronary Artery Disease

DrugEvolocumab

West China Hospital

Phase 4

232

Xi’an, Chengdu

2025-11-19

Recruiting

Closed-Loop Neurofeedback Targeting the Right Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety

NCT07238920Coronary Heart Disease (CHD), Anxiety Disorders

Shenyang Medical College

Not applicable

Shenyang

2025-11-19

Recruiting

GVB-2001 Gene Therapy Via Intracameral Injection for the Treatment of Primary Open Angle Glaucoma

NCT06921317Primary Open-Angle Glaucoma (POAG)

IVIEW Therapeutics Inc.

Phase 1/2

Suzhou

2025-11-19

Recruiting

High-Intensity, Low-Frequency Periodic rTMS Over the Right Dorsolateral Prefrontal Cortex on Cardiac Autonomic Regulation in Women With Recurrent Pregnancy Loss and Anxiety

NCT07233278Recurrent Pregnancy Loss(RPL), Anxiety

Shenyang Medical College

Not applicable

Shenyang

2025-11-19

Recruiting

Efficacy and Safety Study of DC-CIK Cell Therapy Combined With Epaloliposide, Vortexil, and Regorafenib as Third-line Treatment for Advanced Colorectal Cancer.

NCT07343791DC-CIK Treatment, Regorafenib, Colorectal Cancer, Immune Combination Therapy

JIANG LONGWEI

Early Phase 1

Nanjing

2025-11-19

Recruiting

The Long-term Effect of Remote Ischemic Conditioning on Main Organs in ASVCD Patients With Very High Risks

NCT07270887ASCVD

General Hospital of Shenyang Military Region

Observational

2,800

Shenyang

2025-11-19

Not yet open

A Study of BPR-6023021 in Advanced Solid Tumors With Bone Metastases

NCT07249892Metastatic Solid Tumors

Chengdu Syncor Pharmaceutical Co., Ltd.

Phase 1/2

195

Guangzhou

2025-11-19

Active, closed

A Study to Learn About How Well BAY 3401016 Works in Adults With Alport Syndrome

NCT07211685Alport Syndrome

Bayer

Phase 2

Beijing, Guangzhou, Wuhan, Hangzhou

2025-11-19

Recruiting

GenSci139 in Patients With Advanced Solid Tumors

NCT07230977Advanced Solid Tumors

Changchun GeneScience Pharmaceutical Co., Ltd.

Phase 1

280

Jinan

2025-11-19

Recruiting

Reduced-dose Versus Conventional-dose Intensity-modulated Radiation Therapy for Locally Advanced Nasopharyngeal Carcinoma With Remission After Induction Chemotherapy and Immunotherapy

NCT07328841Nasopharyngeal Carcinoma (NPC)

Ming-Yuan Chen

Phase 3

456

Guangzhou, Shantou, Zhongshan, Nanning, Wuzhou, Wuhan, Changsha, Guangdong

2025-11-18

Recruiting

Hypofractionated Radiotherapy Plus Immunochemotherapy for Neoadjuvant Treatment of Gastroesophageal Junction Adenocarcinoma

NCT07182565Gastroesophageal Junction Adenocarcinoma, Hypofractionated Radiotherapy

DrugTS-1

West China Hospital

Phase 1/2

Xiamen, Chengdu

2025-11-18

Recruiting

A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia

NCT07175493Autoimmune Cytopenia, Immune Thrombocytopenia (ITP), Autoimmune Hemolytic Anemia, Evans Syndrome

DrugCM336

Keymed Biosciences Co.Ltd

Phase 1/2

158

Zhengzhou, Changzhi, Tianjin

2025-11-18

Recruiting

Transcutaneous Electrical Acupoint Stimulation for Postoperative Urinary Retention After Radical Surgery for Cervical Cancer

NCT07235371Postoperative Urinary Retention (POUR)

Lu Chao

Not applicable

Hangzhou

2025-11-18

Recruiting

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

NCT07228832Metastatic Colorectal Cancer (CRC)

DrugsIvonescimab·Leucovorin·Adrucil·Oxaliplatin

Summit Therapeutics

Phase 3

900

Beijing, Fuzhou, Guangzhou, Foshan, Shenzhen, Zhuhai, Haikou, Shijiazhuang

2025-11-18

Recruiting

A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity

NCT07243171Overweight and/or Obesity, Weight Management

DrugEcnoglutide

Hangzhou Sciwind Biosciences Co., Ltd.

Phase 1/2

126

Beijing

2025-11-18

Recruiting

Zanubrutinib Combined With Rituximab in the Treatment for Patients With Marginal Zone Lymphoma

NCT07233720Marginal Zone Lymphoma

DrugsZanubrutinib·Rituximab

Henan Cancer Hospital

Observational

Zhengzhou

2025-11-18

Recruiting

A Phase 1 Study of HDM2017 in Advanced Solid Tumors

NCT07274085Solid Tumors

DrugHDM2017

Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.

Phase 1

Beijing

2025-11-18

Recruiting

Study to Assess Efficacy and Safety of HSK39297 Tablets in Patients With LN

NCT07363460Lupus Nephritis (LN)

DrugsHSK39297 200mgQD·HSK39297 300mgQD

Haisco Pharmaceutical Group Co., Ltd.

Phase 2

105

Nanjing

2025-11-18

Not yet open

A Clinical Study to Explore the Safety and Efficacy of CT0991 in Relapsed/ Refractory Acute Myeloid Leukemia

NCT07233018Relapsed/Refractory Acute Myeloid Leukemia(AML)

MEI HENG

Phase 1

Wuhan

2025-11-18

Recruiting

Feasibility of Wearables in Dementia Care in Rural Taiwan

NCT07249918Alzheimer's Dementia, Neuropsychiatric Symptoms Related to Neurodegenerative Disease, Wearable Devices, Caregiver Burden of People With Dementia

China Medical University Hospital

Not applicable

2025-11-18

Active, closed

Reduced-dose vs Standard-dose Irradiation for Low-risk Clinical Target Volume in Nasopharyngeal Carcinoma.

NCT07201337Nasopharyngeal Cancinoma (NPC)

Sun Yat-sen University

Phase 3

700

Dongguan, Guangzhou, Shantou, Shenzhen, Zhanjiang

2025-11-17

Recruiting

A Prospective, Interventional, Exploratory Study Evaluating the Efficacy of Small-Molecule Compound XJH05 Ointment in the Treatment of Plaque Psoriasis

NCT07780929Psoriasis, Psoriasis (PsO)

DrugCalcipotriol

Xijing Hospital

Not applicable

Xi'an

2025-11-17

By invitation

Clinical Evaluation of [68Ga]Ga-NOTA-RF PET Imaging Targeting RFVT3 in Patients With Pituitary Tumors

NCT07254104Pituitary Neoplasms

Peking Union Medical College Hospital

Early Phase 1

Beijing

2025-11-17

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of SXRN Injection in Patients With Cancer Cachexia

NCT07231120Cachexia-Anorexia Syndrome, Solid Tumor Malignancies

DrugSXRN

Jiangsu Nutai Biologics Co., Ltd

Phase 1

Beijing

2025-11-17

Recruiting

Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection

NCT07605611Rectal Cancer, Anastomotic Leakage

DrugSomatostatin

Tongji Hospital

Not applicable

Ezhou, Wuhan

2025-11-17

Recruiting

Evaluate the Safety, Tolerability, and Preliminary Efficacy of EVM14 Alone and in Combination in Patients With Selected Solid Tumors

NCT07095868Selected Types of Solid Tumor

Everest Medicines (Beijing) Co., Ltd.

Phase 1/2

Changsha, Nanjing, Shanghai

2025-11-17

Recruiting

Evaluating Presbyopia-Correcting IOLs in Complex Cataract Cases With Anterior Segment Abnormalities

NCT07321756Lens Diseases

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

320

Hangzhou

2025-11-17

Recruiting

Study Evaluating Safety of BT01001 Ophthalmic Solution

NCT07313722Healthy

Beyang Therapeutics Co., Ltd.

Phase 1

Shanghai

2025-11-17

Recruiting

This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

NCT07290803Atopic Dermatitis

Sanofi

Observational

1,000

Beijing, Shenzhen, Changsha, Xi’an, Chengdu, Hangzhou, Ningbo, Chongqing

2025-11-17

Recruiting

Study on Gastric Emptying Effect and Drug-Drug Interactions of GZR18 Injection

NCT07128888Obesity or Overweight

Gan & Lee Pharmaceuticals.

Phase 1

Beijing

2025-11-17

Recruiting

Sintilimab Combined With Bevacizumab Biosimilar as Adjuvant Treatment After Resection of Ruptured Hepatocellular Carcinoma (CLEAR-2)

NCT07331883Hepatocellular Carcinoma (HCC)

DrugsBevacizumab biosimilar·Sintilimab

Ruijin Hospital

Phase 2

Sanming, Changchun, Shanghai

2025-11-17

Recruiting

Durvalumab Consolidation After Chemoradiation Therapy for Limited Stage SCLC in China

NCT07161388Limited Stage Small-Cell Lung Cancer

AstraZeneca

Observational

200

Beijing, Cangzhou, Dongguan, Fuzhou, Guangzhou, Huzhou, Jinan, Nanjing

2025-11-17

Recruiting

Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress

NCT07280481Depression, Anxiety, Emotional Disorders

Peking University

Not applicable

500

Beijing

2025-11-16

Recruiting

A Study on Predicting the Risk of Distant Metastasis in Breast Cancer Using AI-Generated Spatial Pathological Maps

NCT07244094Breast Cancer

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

400

Changchun, Tianjin, Hangzhou

2025-11-15

Recruiting

Firstline Sequential AG and mFOLFOX Combined With Serplulimab and Bevacizumab Versus AG Chemotherapy Alone in Advanced Pancreatic Cancer

NCT07235930Non-Resectable Pancreas Carcinoma

DrugSerplulimab and Bevacizumab

Zhejiang Cancer Hospital

Phase 3

292

Hangzhou

2025-11-15

Recruiting

Dalpiciclib Combined With Endocrine Therapy and Metronomic Capecitabine vs Dalpiciclib Combined With Endocrine Therapy for First-line Treatment

NCT07467330Breast Cancer

DrugsDalpiciclib·Capecitabine

Fujian Cancer Hospital

Phase 3

258

Fuzhou

2025-11-15

Recruiting

Neural Mechanisms of Temporal Interference Stimulation on Improving Social Reward Function in Depression

NCT07287878Depression

Shanghai Mental Health Center

Not applicable

120

Shanghai

2025-11-15

Recruiting

Jockey Club Support Project

NCT07136064Family Relations, Resilience, Emotion Regulation

City University of Hong Kong

Not applicable

450

Shenzhen

2025-11-15

Recruiting

Sepsis-associated Thrombocytopenia and Platelet Transfusion （STAPT）

NCT07230067Sepsis, Sepsis and Coagulopathy

Nanfang Hospital, Southern Medical University

Observational

1,500

Guangzhou

2025-11-15

Recruiting

Yiyuancong for the Treatment of Sudden Sensorineural Hearing Loss

NCT07505667Sudden Hearing Loss, Sensorineural Hearing Loss

Guangdong Provincial People's Hospital

Not applicable

128

Guangzhou, Shenzhen, Zhongshan, Liuzhou, Ganzhou

2025-11-15

Recruiting

INVIGORATE: A Study of QL1706 and Bevacizumab in Advanced First-Line Ovarian Clear Cell Carcinoma

NCT07002346Ovarian Clear Cell Carcinoma

DrugsLenvatinib·Paclitaxel·Bevacizumab·Carboplatin

Tongji Hospital

Phase 3

226

Wuhan

2025-11-15

Recruiting

TIPS With or Without BCAA

NCT07281846BCAA, Cirrhosis, Portal Hypertension Related to Cirrhosis, Sarcopenia

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Not applicable

164

Wuhan

2025-11-15

Recruiting

QL1706 Combined With Chemotherapy and Anlotinib for the Treatment of Recurrent Ovarian Cancer

NCT07286240Treatment of Recurrent Ovarian Cancer

DrugLenvatinib

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Phase 2

Guangzhou

2025-11-15

Active, closed

Phase II Clinical Trial of Lyophilized Herpes Zoster mRNA Vaccine in Adults Aged 40 Years or Above

NCT07285278Varicella-zoster Virus

DrugABO1108

Suzhou Abogen Biosciences Co., Ltd.

Phase 2

300

Liuzhou

2025-11-15

Recruiting

Nimotuzumab Combined With Toripalimab and Chemotherapy for Locally Advanced Tonsillar Cancer

NCT07353723Head & Neck Cancer

DrugsCarboplatin (AUC 5)·Carboplatin (AUC 6)·Nimotuzumab·Toripalimab

Tang-Du Hospital

Phase 2

Shanxi

2025-11-15

Recruiting

Real-world Outcomes of Peripheral T-cell Lymphoma: A Multicenter Retrospective and Prospective Cohort Study

NCT07270861Peripheral T-Cell Lymphoma

Fudan University

Observational

3,000

Shanghai

2025-11-15

Not yet open

Safety and Preliminary Efficacy of a Metabolically Armed Chimeric Antigen Receptor T Cell Therapy Targeting EGFRvIII for Recurrent Glioblastoma

NCT07244666Glioblastoma (GBM)

Second Affiliated Hospital, Zhejiang University, School of Medicine

Early Phase 1

Hangzhou

2025-11-15

Active, closed

Multicenter, Double-blind, and Randomized Controlled Trial of Ultra-Distal TENS Device for Migraine Treatment

NCT07451158Migraine

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

206

Hangzhou

2025-11-15

Recruiting

A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SYH2070 Injection

NCT07241923Healthy Subjects (HS)

DrugSYH2070

CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Phase 1

Shijiazhuang

2025-11-15

Recruiting

An Exploratory Clinical Study on the Safety and Efficacy of Anti-CD19/BCMA U CAR-T Cells in the Treatment of Relapsed/Refractory Immune-mediated Kidney Disease

NCT07241468Relapsed/Refractory Immune Nephropathy, Relapsed/Refractory Immune-mediated Kidney Disease

Changhai Hospital

Early Phase 1

Shanghai

2025-11-15

Recruiting

A Clinical Study of PA5 in Patients With Advanced Solid Tumors

NCT07702162Advanced Solid Tumors, Cancer

Chongqing Peg-Bio Biopharm Co., Ltd.

Phase 1

Fuzhou, Shanghai

2025-11-14

Recruiting

GKL-006 Injection Plus TACE Versus TACE Alone in Patients With Unresectable Hepatocellular Carcinoma

NCT07209813Hepatocellular Carcinoma (HCC), Unresectable Hepatocellular Cancer

DrugGKL-006

Beijing Gene Key Life Technology Co., Ltd

Phase 2

Beijing, Zhengzhou, Changsha, Nanjing, Nanchang, Hangzhou

2025-11-14

Recruiting

Comparison of Diagnostic Accuracy Between XTR004 PET MPI and the Composite Index of Quantitative Coronary Angiography (QCA) and Fractional Flow Reserve (FFR)

NCT07439133Coronary Artery Disease(CAD)

Sinotau Pharmaceutical Group

Phase 3

395

Beijing, Foshan, Tianjin

2025-11-14

Recruiting

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis

NCT07219420Palmoplantar Pustulosis

DrugBimekizumab

UCB Biopharma SRL

Phase 3

320

Beijing, Chengdu, Chongqing, Guangzhou, Hangzhou, Jinan, Shanghai, Shenzhen

2025-11-14

Recruiting

Comparative Evaluation of 68Ga-FAPI and 68Ga-DOTATATE PET/CT and PET/MRI in Thyroid Eye Disease

NCT07835607Thyroid Eye Disease

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Observational

Chongqing

2025-11-14

Recruiting

Artificial Intelligence-Assisted vs Surgeon-Planned Trajectories in Freehand Femoral Neck Screw Fixation

NCT06937138Femoral Neck Fractures

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Not applicable

334

Wuhan

2025-11-14

Recruiting

A Study of Lutetium [177Lu] BL-ARC001 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors

NCT07232407Gastrointestinal Tumors, Solid Tumors

DrugLutetium [177Lu] BL-ARC001

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Chengdu

2025-11-14

Recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Safety and Efficacy of Onradivir Tablets in Participants Aged 12 to 17 Years With Uncomplicated Influenza A.

NCT07229547Influenza

Ruijin Hospital

Phase 3

150

Shanghai

2025-11-14

Active, closed

Clinical Trial of Quadrivalent Subunit Influenza Vaccine (Adjuvant) in Chinese Population Aged 65 Years and Older

NCT07421037Influenza, Influenza Vaccine

DrugMF59

Ab&B Bio-tech Co., Ltd.JS

Phase 1

Shiyan

2025-11-13

Recruiting

A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors

NCT07241936Advanced Solid Tumors

DrugsDP303c·SYS6043·SYS6010·Sirolimus

CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Phase 1/2

444

Shanghai

2025-11-13

Recruiting

A Study of DEG6498 in Participants With Solid Tumors

NCT07244835Malignant Neoplasms

Degron Therapeutics Co.

Phase 1

100

Beijing, Guangzhou

2025-11-13

Recruiting

Adaptive Immunotherapy for Nasopharyngeal Carcinoma

NCT07154069Nasopharyngeal Cancinoma (NPC)

DrugsConcurrent chemoradiotherapy·CCRT·Toripalimab·Capecitabine

Sun Yat-sen University

Phase 3

802

Guangzhou

2025-11-13

Recruiting

Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases

NCT07236801Systemic Lupus Erythematosus (SLE), Systemic Sclerosis, Sjogren's Syndrome (SS), Inflammatory Myopathy

DrugYTS109 cell

China Immunotech (Beijing) Biotechnology Co., Ltd.

Phase 1

Xuzhou

2025-11-13

Not yet open

Diagnostic Accuracy of Oral Images, OPGs, and Questionnaires vs. Clinical Assessment for Periodontal Disease

NCT07164573Periodontal Diseases, Gingivitis, Periodontitis

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Observational

2,000

Shanghai

2025-11-13

Recruiting

Sac-TMT Plus KL-A167 in PD-L1+, HR+/HER2- Metastatic Breast Cancer After CDK4/6 Inhibitors

NCT07258108Breast Cancer

Sun Yat-sen University

Phase 2

Guangzhou

2025-11-13

Active, closed

Clinical Trial of Subunit Influenza Vaccine (Adjuvant) in Chinese Population Aged 65 Years and Older

NCT07421050Influenza, Influenza Vaccine

DrugMF59

Ab&B Bio-tech Co., Ltd.JS

Phase 1

Xiangyang

2025-11-13

Recruiting

Improving Neuroprotective Strategy for Ischemic Stroke Before Endovascular Thrombectomy by Intravenous Tirofiban

NCT07135089Stroke, Ischemic

General Hospital of Shenyang Military Region

Phase 3

870

Shenyang

2025-11-13

Recruiting

Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit Constipation

NCT07277907Slow Transit Constipation, Pharmacotherapy

DrugLubiprostone

Third Military Medical University

Phase 3

346

Bishan, Hechuan, Shapingba, Yuzhong, Lanzhou, Shijiazhuang, Harbin, Wuhan

2025-11-13

Recruiting

HS-20117-2 Injection in Patients With Advanced Solid Tumors

NCT07775703Advanced Solid Tumors

Hansoh BioMedical R&D Company

Phase 1

Guangzhou

2025-11-13

Recruiting

Rifampin-combined Antibiotic Therapy for Staphylococcal PJI

NCT07313215Periprosthetic Joint Infection

DrugRifampicin

First Affiliated Hospital of Fujian Medical University

Not applicable

428

Fuzhou

2025-11-13

Recruiting

Registry Study of Cerebral Small Vessel Disease

NCT07342075Cerebral Small Vessel Diseases, Cognitive Impairment, Diffusion Tensor Imaging

Dongzhimen Hospital, Beijing

Observational

Beijing

2025-11-13

Recruiting

Phase I Study of SHR-2173 Injection in Patients With Primary Immune Thrombocytopenia

NCT07206758Immune Thrombocytopenia

DrugSHR-2173

Guangdong Hengrui Pharmaceutical Co., Ltd

Phase 1

Wuhan

2025-11-12

Recruiting

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

NCT07109219B-cell Acute Lymphoblastic Leukemia (B-ALL)

AstraZeneca

Phase 1/2

Guangzhou, Tianjin

2025-11-12

Recruiting

A Phase Ib/III Study of Suvemcitug Plus FTD/TPI in Participants With Refractory Metastatic Colorectal Cancer

NCT07361003Refractory Metastatic Colorectal Cancer

Jiangsu Simcere Pharmaceutical Co., Ltd.

Phase 3

464

Fuzhou, Harbin, Nanjing, Jinan, Tianjin, Hangzhou

2025-11-12

Recruiting

AT1019 Plus SBRT and PD-1 Inhibitor for Advanced Solid Tumors: An IIT Study

NCT07285395Advanced Solid Tumors

DrugSBRT

The Affiliated Hospital of Xuzhou Medical University

Phase 1

Xuzhou

2025-11-12

Recruiting

Study to Evaluate the Efficacy and Safety of Neo-Adjuvant TACE and Atezolizumab Plus Bevacizumab Therapy for High-Risk Recurrent Hepatocellular Carcinamo

NCT07239245Resectable Hepatocellular Carcinoma With High Risk of Recurrence

DrugsAtezolizumab·Bevacizumab

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 2

Beijing, Zhengzhou, Shenyang, Taiyuan

2025-11-12

Recruiting

First-in-human Study of 7MW4911 in Patients With Advanced Solid Tumors

NCT07265622Solid Tumors

Drug7MW4911

Mabwell (Shanghai) Bioscience Co., Ltd.

Phase 1/2

200

Shanghai

2025-11-12

Recruiting

A Randomised, Open-label, Multicentre Phase III Clinical Study to Evaluate the Efficacy and Safety of JS105 Combined With Dalpiciclib and Fulvestrant Compared With Dalpiciclib and Fulvestrant in Patients With PIK3CA-mutated, HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer.

NCT07207070Breast Cancer

DrugsJS105·Dalpiciclib·Fulvestrant

Risen (Suzhou) Pharma Tech Co., Ltd.

Phase 3

312

Beijing, Zhengzhou

2025-11-12

Recruiting

A Phase II Clinical Study of FH-006 for Injection Combined With Other Anticancer Therapies in Subjects With Lung Cancer

NCT07241767Lung Cancer

DrugsFH-006·SHR-8068·BP102·Adebrelimab

Jiangsu HengRui Medicine Co., Ltd.

Phase 2

200

Guangzhou

2025-11-12

Recruiting

Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH)

NCT07805967Multiple System Atrophy, Dementia With Lewy Bodies (DLB), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD)

Second Affiliated Hospital of Soochow University

Observational

500

Changshu, Huai'an, Kunshan, Nanjing, Nantong, Suqian, Suzhou, Xuzhou

2025-11-12

Recruiting

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

NCT07225504Secondary Progressive Multiple Sclerosis (SPMS)

DrugRemibrutinib

Novartis Pharmaceuticals

Phase 3

1,275

Guangzhou, Zunyi, Zhengzhou, Wuhan, Hohhot, Suzhou, Changchun, Shenyang

2025-11-11

Recruiting

Evaluation of NWRD08 for HPV-16 and/or HPV-18 Related Cervical HSIL

NCT07175662High-grade Squamous Intraepithelial Lesion (HSIL)

Newish Biotech (Wuxi) Co., Ltd.

Phase 2

150

Beijing, Taiyuan

2025-11-11

Recruiting

Treatment of Pediatric Bronchiolitis Obliterans by Airway Basal Stem Cells

NCT07239895Pediatric Bronchiolitis Obliterans

Regend Therapeutics

Early Phase 1

Shanghai

2025-11-11

Recruiting

Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC

NCT06998758Neoadjuvant Chemotherapy, Weight Loss

DrugMegestrol Acetate

Sixth Affiliated Hospital, Sun Yat-sen University

Phase 3

Guangzhou

2025-11-11

Recruiting

Study of TI-0093 Injection With Recurrent/Metastatic HPV-16 Positive Solid Tumors

NCT07081984HPV 16+ Recurrent or Metastatic Cancer, HNSCC, Cervical Cancer

Therorna

Phase 1

Shanghai

2025-11-11

Recruiting

Sulbactam-Durlobactam in CRAB Infection: A Real-World Cohort Study

NCT07601711Carbapenem-Resistant Acinetobacter Baumannii Infection, Bloodstream Infection, Pneumonia, Sepsis

DrugSulbactam -Durlobactam

Sichuan Provincial People's Hospital

Observational

200

Chengdu

2025-11-11

Recruiting

Evaluating the Efficacy and Safety of Teprotumumab N01 in Patients With Thyroid Eye Disease.

NCT07423013Thyroid Eye Disease

Peking University Third Hospital

Not applicable

Beijing

2025-11-11

Recruiting

AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL

NCT07215585Large B-cell Lymphoma

DrugsR-mini-CHOP·Surovatamig

AstraZeneca

Phase 3

420

Beijing, Changchun, Chengdu, Chongqing, Fuzhou, Guangzhou, Guiyang, Haikou

2025-11-11

Recruiting

Real-world Study of Aflibercept 8 mg in nAMD

NCT07640997Neovascular Age-Related Macular Degeneration (nAMD)

DrugAflibercept

Peking University People's Hospital

Observational

300

Beijing, Fuzhou, Shenzhen, Zunyi, Harbin, Nanyang, Wuhan, Hohhot

2025-11-11

Recruiting

Vitamin D Status and Multi-Omics Profiles in Primary Osteoporosis

NCT07296471Primary Osteoporosis

Dr. Li Chen

Observational

120

Yichang

2025-11-11

Recruiting

Prospective Multicenter Real-world Study of Surufatinib in Patients With Advanced Neuroendocrine Neoplasms

NCT07272512Neuroendocrine Tumors, Neuroendocrine Neoplasms

DrugSurufatinib

Shanghai Zhongshan Hospital

Phase 4

350

Shanghai

2025-11-11

Recruiting

Symplicity China Study

NCT07081243Resistant Hypertension

Medtronic Vascular

Observational

500

Shanghai

2025-11-11

Not yet open

Study of Stapokibart Injection in Subjects With Moderate to Severe Bullous Pemphigoid

NCT07210554Bullous Pemphigoid (BP)

DrugStapokibart

Chengdu Kangnuoxing Biopharma,Inc.

Phase 3

200

Beijing

2025-11-11

Recruiting

Study of LW231 in Participants With Chronic Hepatitis B

NCT07179575Chronic HBV Infection

Shanghai Longwood Biopharmaceuticals Co., Ltd.

Phase 1/2

270

Hangzhou

2025-11-11

Recruiting

Pharmacokinetics of Olverembatinib in Participants With Hepatic Impairment

NCT07282093Pharmacokinetic, Olverembatinib

DrugOlverembatinib

Ascentage Pharma Group Inc.

Phase 1

Suzhou

2025-11-11

Recruiting

A Phase II Study of PEG-rhGH Injection for Short Children Born Small for Gestational Age: Efficacy, Safety, and Pharmacokinetics

NCT07260500Short Stature Children Born Small for Gestational Age (SGA)

DrugPEG-rhGH

Changchun GeneScience Pharmaceutical Co., Ltd.

Phase 2

Wuhan

2025-11-11

Recruiting

Intravenous Thrombolysis Combined With Tirofiban in Acute Ischemic Stroke

NCT07290751Acute Ischemic Stroke

DrugTirofiban

Beijing Anzhen Hospital

Phase 4

976

Beijing

2025-11-11

Recruiting

A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer and Other Solid Tumors

NCT07232420Non Small Cell Lung Cancer, Solid Tumor

DrugBL-M24D1

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Guangzhou

2025-11-11

Recruiting

Iparomlimab/Tuvonralimab Injection Plus CCRT in LACC

NCT07232654LOCALLY ADVANCED CERVICAL CANCERS

DrugsLenvatinib·Cisplatin

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 2

Beijing

2025-11-11

Recruiting

Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults

NCT06836440Cognition Disorders

Yuju Wu

Not applicable

964

Ya'an

2025-11-10

Recruiting

BDB-001 Phase III Trial in ANCA-Associated Vasculitis

NCT07168161ANCA Associated Vasculitis (AAV)

DrugsAzathioprine·Prednisone·Rituximab·Cyclophosphamide

Staidson (Beijing) Biopharmaceuticals Co., Ltd

Phase 3

300

Beijing, Chongqing, Xiamen, Lanzhou, Guangzhou, Meizhou, Shaoguan, Shenzhen

2025-11-10

Recruiting

Exploratory Study of UX-GIP001 Cell Therapy in Adult Patients With Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)

NCT07244328Epilepsy, MTLE

DrugUX-GIP001

Second Affiliated Hospital, Zhejiang University, School of Medicine

Early Phase 1

Hangzhou

2025-11-10

Recruiting

The Treatment of Liver Injury After Liver Resection With Polyene Phosphatidylcholine

NCT07150624Hepatocellular Carcinoma (HCC), Liver Diseases

Anhui Provincial Hospital

Phase 4

Hefei

2025-11-10

Active, closed

Effectiveness and Cost-effectiveness of VTE Prevention Strategies in Gynecological Surgery

NCT07455253Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Gynecological Surgery

Affiliated Hospital of Nantong University

Observational

234

Nantong

2025-11-10

Recruiting

Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease

NCT07228364Autosomal Dominant Polycystic Kidney Disease

DrugAZD1613

AstraZeneca

Phase 1

Chengdu, Hangzhou, Nanjing, Shanghai, Wuhan, Xiamen

2025-11-10

Recruiting

A Randomized Controlled Trial Evaluating the Feasibility and Preliminary Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Advanced Epithelial Ovarian Cancer

NCT07544030Ovarian Cancer

tongweihua

Phase 3

Changchun

2025-11-10

Recruiting

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

NCT07186101Ulcerative Colitis

DrugsZotemtegrast·Mirikizumab

Eli Lilly and Company

Phase 2

252

Changzhou, Chongqing, Fuzhou, Hangzhou, Kunming, Nanjing, Qingdao, Shenyang

2025-11-10

Recruiting

GP350 CAR-T for Relapse/Refractory and Epstein-Barr Virus Infection Associated Lymphoid Neoplasms

NCT07306156EBV Associated Lymphoid Neoplasms

Zhimin Zhai

Phase 1/2

Hefei

2025-11-10

Recruiting

Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on on Perioperative Sedation Related Adverse Events in Elderly ERCP Patients

NCT07017283Biliary and Pancreatic Diseases, Endoscopic Retrograde Cholangiopancreatography (ERCP)

Gang Chen

Not applicable

170

Hangzhou

2025-11-10

Recruiting

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

NCT07181681Solid Tumors, Advanced Solid Tumor

BeOne Medicines

Phase 1

Beijing, Chongqing, Xiamen, Harbin, Zhengzhou, Shanghai, Chengdu, Hangzhou

2025-11-10

Recruiting

Health Behavior Change in High-Risk Colorectal Cancer Individuals

NCT07262840Health Behavior, Colorectal Neoplasms, Primary Prevention/Methods

China Medical University, China

Not applicable

Shenyang

2025-11-10

Active, closed

Efficacy and Safety of ZSP1273 in Children 12-17 Years Old With Influenza A

NCT07229820Influenza A

Guangdong Raynovent Biotech Co., Ltd

Phase 3

157

Shanghai

2025-11-08

Not yet open

Analgesic Effect of TENS-WAA Combined With Tramadol Hydrochloride During Oocyte Retrieval Surgery

NCT07212127Oocyte Retrieval for IVF, Pain

First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University

Not applicable

Shanghai

2025-11-08

Recruiting

A Phase I Study of SIM0609 in Adult Participants With Locally Advanced/Metastatic Solid Tumors

NCT07265921Advanced Solid Cancer

Jiangsu Simcere Pharmaceutical Co., Ltd.

Phase 1

232

Beijing, Nanjing, Shanghai, Tianjin, Wuhan

2025-11-07

Active, closed

A Real-world Study on the Treatment of Adult B-cell Acute Lymphoblastic Leukemia With CNCT-19

NCT07269587ALL (Acute B-Lymphoblastic Leukemia), CAR-T Cell Therapy

DrugSingle of Inaticabtagene autoleucel

Ruijin Hospital

Observational

275

Shanghai

2025-11-07

Recruiting

A Study to Evaluate the Efficacy and Safety of 608 in Adult Subjects With Active Ankylosing Spondylitis(AS)

NCT07261644Ankylosing Spondylitis

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

Phase 3

500

Beijing

2025-11-07

Recruiting

Phase III Clinical Study Evaluating the Safety, Pharmacokinetics, and Efficacy of JKN2301 Dry Suspension in Pediatric Patients Aged 2 to Under 12 Years With Influenza

NCT07357051Respiratory Viral Infection

DrugOseltamivir

Joincare Pharmaceutical Group Industry Co., Ltd

Phase 3

177

Guangzhou

2025-11-07

Recruiting

Efficacy and Safety of ACC017 Tablets Compared With Dolutegravir Sodium Tablets in Treatment-Naïve Adults With Human Immunodeficiency Virus Type 1 (HIV-1)

NCT07711223Infection, Human Immunodeficiency Virus

DrugACC017

Jiangsu Aidea Pharmaceutical Group Co., Ltd.

Phase 1/2

660

Beijing

2025-11-07

Recruiting

A Study Comparing QLS32015 Monotherapy Versus Pomalidomide, Dexamethasone (Pd) or Selinexor, Dexamethasone (Sd) in Participants With Relapsed or Refractory Multiple Myeloma

NCT07138209Relapsed or Refractory Multiple Myeloma

DrugsQLS32015·Selinexor·Pomalidomide·Dexamethasone

Qilu Pharmaceutical Co., Ltd.

Phase 3

228

Tianjin

2025-11-07

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of GT801 Injection in the Treatment of Moderate-to-Severe Refractory Autoimmune Diseases

NCT07333118Moderate to Severe Refractory Autoimmune Disease

DrugGT801

Grit Biotechnology

Early Phase 1

Shanghai

2025-11-07

Recruiting

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

NCT06902740Intracranial Atherosclerosis, Intracranial Artery Stenosis, Atherosclerotic Plaque

Peking Union Medical College Hospital

Phase 4

300

Beijing, Meizhou, Cangzhou, Qinhuangdao, Shijiazhuang, Tangshan, Harbin, Zhengzhou

2025-11-07

Recruiting

A Study to Investigate the Efficacy and Safety of SHR-1905 in Patients With Moderate-to-severe Atopic Dermatitis

NCT07211542Moderate-to-severe Atopic Dermatitis

DrugGSK5784283

Guangdong Hengrui Pharmaceutical Co., Ltd

Phase 2

Guangzhou

2025-11-07

Not yet open

Evaluation of the Efficacy and Safety of Magnetically-controlled Capsule Gastroscopy for Postoperative Assessment in Elderly Patients and Patients With Underlying Diseases

NCT06029608Evaluation,Efficacy,Safety

Shanghai Jiao Tong University School of Medicine

Observational

120

Shanghai

2025-11-06

Active, closed

A Parental Support Intervention for Children's Nature-Based Physical Activity: A Randomized Controlled Trial

NCT07674641Health Behavior, Physical Activity Promotion

South China Normal University

Not applicable

Guangzhou

2025-11-06

Recruiting

A Study of QL1706 Combined With Short-Cycle Anthracyclines or Taxanes for the Treatment of Early-Stage TNBC

NCT07178171TNBC, Triple Negative Breast Cancer

DrugsPirarubicin·Nab-paclitaxel·Lenvatinib·Cyclophosphamide

Xijing Hospital

Phase 1

Xi'an

2025-11-06

Recruiting

A Phase IIa, Randomized, Double-Blind, Placebo-Controlled Trial of JKN2403 in COPD

NCT07351734COPD (Chronic Obstructive Pulmonary Disease)

Joincare Pharmaceutical Group Industry Co., Ltd

Phase 2

120

Guangzhou

2025-11-06

Recruiting

Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

NCT07170917Hidradenitis Suppurativa

DrugBrivekimig

Sanofi

Phase 2

208

Chengdu, Guangzhou, Shanghai, Ürümqi

2025-11-06

Recruiting

Efficacy and Safety Trials of Yangxinshi Tablets in the Treatment of Patients With Coronary Heart Disease Complicated by Cardiac Dysfunction

NCT07110415Coronary Heart Disease, Cardiac Dysfunction

DrugYangxinshi

SPH Qingdao Growful Pharmacetical Co.,Ltd

Phase 4

2,708

Haozhou, Beijing, Chongqing, Lanzhou, Guangzhou, Shantou, Zhuhai, Guilin

2025-11-06

Recruiting

A Phase I Study Evaluating the Safety, Tolerability, and Pharmacokinetics of VVN432 Nasal Spray

NCT07259538Chronic Rhinosinusitis (CRS)

VivaVision Biotech, Inc

Phase 1

Beijing

2025-11-06

Recruiting

Effect of Delayed Remote Ischemic Preconditioning on Postoperative Pulmonary Complications in Elderly Patients Having Non-Cardiac Thoracic Surgery

NCT07208500Pulmonary Complications in Surgical Patients

Shanghai Geriatric Medical Center

Not applicable

390

Shanghai

2025-11-06

Recruiting

A Clinical Study of QLC5508 and/or QLH12016 in Combination With Other Anti-tumor Therapies in Subjects With Advanced Prostate Cancer

NCT07198633Advanced Prostate Cancer

DrugsQLC5508·Abiraterone acetate·Enzalutamide

Qilu Pharmaceutical Co., Ltd.

Phase 1/2

212

Tianjin

2025-11-05

Recruiting

A Multicenter, Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of QY201 Tablets in Subjects With Non-Segmental Vitiligo

NCT07712523Adult Subjects With Non-Segmental Vitiligo

DrugQY201 （）

E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd.

Phase 2

200

Shenyang

2025-11-05

Recruiting

Adaptive Adjuvant Sintilimab Therapy Guided by MRD (ADAPT Lung)

NCT07120698NSCLC (Non-small Cell Lung Cancer), MRD, II-IIIB Stages, Adjuvant Immunotherapy

DrugSintilimab

Guangdong Association of Clinical Trials

Phase 2

115

Guangzhou, Chengdu

2025-11-05

Recruiting

Single-port Versus Conventional Laparoscopic Surgery for Radical Proximal Gastric Cancer: A Randomized Controlled Trial

NCT07586384Stomach Neoplasms, Robotic Surgical Procedures

First Affiliated Hospital of Wenzhou Medical University

Not applicable

Wenzhou

2025-11-05

Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

NCT07100080Non-Small Cell Lung Cancer

DrugsIza-bren·Pemetrexed·Cisplatin·Carboplatin

Bristol-Myers Squibb

Phase 2/3

500

Beijing, Chongqing, Fuzhou, Jiangmen, Anyang, Luoyang, Jingzhou, Wuhan

2025-11-05

Recruiting

A Study of YL201 in Combination With Toripalimab and With or Without Cisplatin in Nasopharyngeal Carcinoma.

NCT07258979Recurrent or Metastatic Nasopharyngeal Carcinoma

DrugsTam-Peli·Toripalimab·Cisplatin

MediLink Therapeutics (Suzhou) Co., Ltd.

Phase 1/2

202

Chongqing, Fuzhou, Xiamen, Zhangzhou, Dongguan, Guangzhou, Jiangmen, Shaoguan

2025-11-05

Recruiting

Dalpiciclib Plus Camrelizumab for HCC Patients Who Have Previously Received ICI Treatment

NCT07238881Hepatocellulcar Carcinoma

DrugsDalpiciclib Isetionate·Camrelizumab

Sun Yat-sen University

Phase 2

Guangzhou

2025-11-05

Recruiting

Suture-Mediated Closure System Following Percutaneous Common Femoral Vein Procedures

NCT07554976Percutaneous Intervention Via Common Femoral Vein

Suzhou Hengruihongyuan Medical Technology Co. LTD

Not applicable

136

Shanghai

2025-11-05

Active, closed

A Clinical Study of HT-101 and HT-102 in Patients With Chronic Hepatitis B Virus Infection

NCT07245953Chronic Hepatitis B

DrugsHT-101·HT-102

Suzhou HepaThera Biotech Co., Ltd.

Phase 2

Beijing, Fuzhou, Guangzhou, Qingyuan, Nanning, Zhengzhou, Nanjing, Zhenjiang

2025-11-05

Recruiting

Efficacy and Safety of Tenecteplase Intravenous Thrombolysis in Acute Posterior Circulation Ischemic Stroke Within 4.5-24 Hours After Onset

NCT07094763Acute Ischemic Stroke

The First Affiliated Hospital of University of Science and Technology of China

Not applicable

406

Hefei

2025-11-05

Active, closed

the Safety and Efficacy of Targeted BCMA In Vivo LV Injection for Recurrent or Refractory Autoimmune Diseases

NCT07339540Recurrent or Refractory Systemic Lupus Erythematosus, Recurrent or Refractory IgG4 Related Diseases, Recurrent or Refractory Systemic Sclerosis, Recurrent or Refractory Idiopathic Inflammatory Myopathy

Tongji Hospital

Early Phase 1

Wuhan

2025-11-04

Recruiting

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of SV001 in Patients With Idiopathic Pulmonary Fibrosis

NCT07121413Idiopathic Pulmonary Fibrosis(IPF)

DrugSV001

Shanghai Synvida Biotechnology Co.,Ltd.

Phase 2

Chengdu, Guangzhou, Hangzhou, Nanchang, Nanjing, Neimeng, Shanghai, Tianjin

2025-11-04

Recruiting

PULSAR Combined With Immunotherapy and Chemotherapy

NCT07291947Cholangiocarcinoma

DrugsIparomlimab and Tuvonralimab·Lenvatinib

Wang Xin

Phase 1/2

Chengdu

2025-11-04

By invitation

Application Study of Individualized Mechanical Power Titration Strategy Based on PiCCO (Pulse Index Continuous Cardiac Output) Monitoring Parameters in ARDS Patients

NCT07839234Acute Respiratory Distress Syndrome

Xiamen Hospital of Traditional Chinese Medicine

Observational

130

Xiamen

2025-11-04

Recruiting

Iparomlimab and Tuvonralimab (QL1706) Combined With Chemotherapy for Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer

NCT07315854Gastric Cancer (GC), Gastroesophageal Junction Cancer, Advanced Gastric Cancer, Metastatic Gastric Cancer

DrugsIparomlimab and Tuvonralimab·Lenvatinib

Beijing Friendship Hospital

Phase 2

Beijing

2025-11-04

Recruiting

AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC)

NCT07544784Colorectal Cancer Liver Metastases (CRLM)

Fudan University

Phase 2

Shanghai

2025-11-04

Recruiting

A Phase II Study of Tislelizumab Plus Anlotinib Consolidation After Chemoradiotherapy in LS-SCLC

NCT07815223SCLC, Limited Stage

DrugsAnlotinib·Tislelizumab

Yantai Yuhuangding Hospital

Phase 2

Yantai

2025-11-04

Recruiting

CEA CAR-T Therapy After Cytoreduction in Colorectal Cancer Patients With Peritoneal Metastases

NCT07247396Peritoneal Metastases From Colorectal Cancer

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 1

Hangzhou

2025-11-03

Active, closed

A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

NCT07108283Nonsegmental Vitiligo

DrugZasocitinib

Takeda

Phase 2

207

Wuhan, Xi'an, Shanghai, Kunming, Hangzhou

2025-11-03

Recruiting

Perioprative Study of IBI363 in Patients With MHC-II-Negative Locally Advanced Gastric Cancer

NCT07325630IBI363 + Chemotherapy

DrugLenvatinib

Zhejiang Cancer Hospital

Phase 2

Hangzhou

2025-11-03

Recruiting

A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

NCT07223840Smoking

DrugBrenipatide

Eli Lilly and Company

Phase 2

222

Beijing, Chengdu, Chongqing, Hangzhou, Linhai, Ningbo, Shenzhen

2025-11-03

Recruiting

CHinese ischEmic Stroke Beyond 4.5 Hours With TeNecteplase Under Optimized Non-Contrast CT Selection

NCT06994975Acute Ischemic Stroke

Huashan Hospital

Phase 3

890

Shanghai

2025-11-03

Recruiting

IBI351 Plus Cetuximab β in Untreated Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation

NCT07198841Lung Cancer (Non-Small Cell)

DrugsIBI351·Cetuximab

Guangdong Association of Clinical Trials

Phase 2

Guangzhou, Beijing, Foshan, Nanchang, Nanning, Shijiazhuang

2025-11-03

Recruiting

Effect of the Intelligent Lipid Management Decision-support System on 1-year LDL-C Target Achievement in Ischemic Stroke or TIA Patients Under Evolocumab Treatment in China

NCT07143149Ischemic Stroke, Transient Ischemic Attack (TIA)

Beijing Tiantan Hospital

Not applicable

4,000

Beijing

2025-11-03

Recruiting

The Impact of 12 Week Retention of Nutrients on Skin and the Perception of Physical Health Status

NCT07383974Healthy Volunteers, Dietary Supplementation, Skin Health, Health Status

ChinaNorm

Not applicable

120

Shanghai

2025-11-03

Recruiting

Effectiveness of Interventional Therapy for Non-Flow-Limiting Vulnerable Plaques

NCT06855537Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques, Thin-cap fIbroatheroma, Acute Coronary Syndromes (ACS)

Beijing Anzhen Hospital

Phase 4

2,190

Beijing

2025-11-03

Recruiting

dCRT vs. Surgery in Resectable ESCC Patients Achieving cCR/PR After Induction Chemoimmunotherapy

NCT07162506Esophageal Cancer

Tianjin Medical University Cancer Institute and Hospital

Phase 2

120

Tianjin

2025-11-03

Recruiting

Triple Branched Stent Graft System for Aortic Arch Lesions

NCT07067840Aortic Arch Aneurysm, Aortic Arch Pseudoaneurysm, Aortic Arch Ulcer

Changhai Hospital

Not applicable

Shanghai

2025-11-03

Recruiting

Effects of Continuous Monitoring and Progressive Regulation of Inflatable Laryngeal Mask Airway Cuff Pressure on Postoperative Pharyngolaryngeal Complications in Elderly Patients

NCT07461467Elderly (People Aged 65 or More), LMA, Randomized Controlled Trial, Laryngeal Mask Airways

First Affiliated Hospital of Chongqing Medical University

Not applicable

146

Chongqing

2025-11-02

By invitation

Consistency of Fluid Tolerance Evaluation Methods and Their Correlation With Clinical Outcomes in Patients With Shock

NCT07373717Shock

Southeast University, China

Observational

Nanjing

2025-11-02

Recruiting

A IIT Study of 177Lu-DOTA-SNA040

NCT07595237Advanced Solid Tumors (Such as Gastric Cancer), Advanced Solid Tumors (Such as Adenocarcinoma at the Gastroesophageal Junction), Advanced Solid Tumors (Such as Pancreatic Cancer), Advanced Solid Tumors (Such as Cholangiocarcinoma)

SmartNuclide Biopharma

Early Phase 1

Shanghai

2025-11-01

Recruiting

Deep Learning-Based Multidimensional Body Composition Mapping for Outcome Prediction in HCC Patients Undergoing TACE

NCT07235410Hepatocellular Carcinoma

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

300

Wuhan

2025-11-01

Recruiting

A Prospective, Multicenter, Randomized Controlled Study on the Efficacy and Safety of Low-dose Carboplatin Combined With Nab-Paclitaxel and Delayed Administration of Serplulimab as First-line Treatment for Advanced Squamous Non-small Cell Lung Cancer

NCT07647094NSCLC

People's Hospital of Quzhou

Phase 2

112

Quzhou

2025-11-01

By invitation

Safety and Efficacy of Yiwoxidan Anti (AK112) Monotherapy in Patients With Metastatic Renal Clear Cell Carcinoma Who Are Intolerant to TKI Treatment: a Prospective, Single Arm, Phase II Clinical Study

NCT07488572Renal Cell Carcinoma (RCC), Metastatic Clear Cell Renal Cell Carcinoma

Sun Yat-sen University

Phase 2

Guangzhou

2025-11-01

Recruiting

Biomarkers for Left Ventricular Reverse Remodeling in Heart Failure (REVERT-HF)

NCT07701876Heart Failure, Heart Failure and Reduced Ejection Fraction

Ruijin Hospital Luwan Branch

Observational

1,740

Shanghai

2025-11-01

Active, closed

Mechanism Study of G Protein-coupled Receptor 81 in Multiple Organ Dysfunction of Heat Stroke

NCT07346443Heat Stroke

Second Affiliated Hospital of Wenzhou Medical University

Observational

100

Wenzhou

2025-11-01

Recruiting

A Real-world Study on the Efficacy and Safety of Menin Inhibitors as Maintenance After Allo-HSCT

NCT07559695Menin Inhibitors, Acute Leukemia, Post Hematopoietic Stem Cell Transplantation, Maintenance Therapy

The First Affiliated Hospital of Soochow University

Observational

Suzhou

2025-11-01

Recruiting

Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke

NCT07294274Post-stroke Depression

Min Su

Observational

488

Chongqing

2025-11-01

Recruiting

RCT of Tocilizumab for Anti-MDA5+DM

NCT07377058Dermatomyositis

DrugsCiclosporin·Tacrolimus·Tocilizumab

Peking Union Medical College Hospital

Not applicable

110

Beijing

2025-11-01

Not yet open

Pulsed Field Ablation of SVC and PV in Paroxysmal Atrial Fibrillation (PASPA Study)

NCT07191626Paroxysmal Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF)

Changhai Hospital

Not applicable

650

Shanghai

2025-11-01

Recruiting

A Phase I Single-arm Clinical Study of Donor NK Cells Infusion Combined With Low-dose Interleukin-2 in the Treatment of Acute Myeloid Leukemia Relapse After Allogeneic Hematopoietic Stem Cell Transplantation.

NCT06641648Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia (AML) Relapse, NK Cell

Peking University First Hospital

Phase 1

Beijing

2025-11-01

Recruiting

Construction and Clinical Validation of a Predictive Model for Postoperative Adjuvant Therapy in Hepatocellular Carcinoma Based on Whole-Slide Digital Pathological Images and Deep Learning

NCT07417800Hepatocellular Carcinoma (HCC), Artificial Intelligent, Adjuvant Chemoradiotherapy, TACE

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

11,000

Hangzhou

2025-11-01

Recruiting

Single-arm, Prospective Clinical Trial of Efficacy and Safety of Daphnetin Capsules Combined With TC Regimen for Targeted Maintenance Therapy After Initial Treatment of Stage III-IV Epithelial Ovarian Cancer (RO/R1)

NCT07495397Epithelial Ovarian Cancer

The First Hospital of Jilin University

Not applicable

Changchun

2025-11-01

Recruiting

Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia

NCT07359586Gastric Cancer, Hepatic Carcinoma, Pulmonary Carcinoma, Pancreatic Carcinoma

Zhejiang University

Observational

1,200

Hangzhou

2025-11-01

Active, closed

Artificial Intelligence Model for Renal Allograft Rejection Identification, Lesion Quantification and Rejection Risk Prediction Based on Prospective Renal Transplant Pathology and Clinical Multidimensional Data

NCT07741552Graft Rejection, Kidney Transplantation, Glomerulonephritis, Polyomavirus Infections

Chen Dajin

Observational

1,000

Hangzhou

2025-11-01

Not yet open

Tenecteplase vs Medical Management in 4.5-24h LVO no Access to EVT

NCT07168278Acute Ischemic Stroke, Large Vessel Occlusion, Tenecteplase, Thrombolysis

DrugTenecteplase

The First Affiliated Hospital of University of Science and Technology of China

Phase 3

794

Hefei

2025-11-01

Recruiting

Integrated TCM - Western Medicine Strategy for Long - Distance Diabetes Management

NCT07265037Diabetes Mellitus, Type 2, Integrated Traditional Chinese Medicine and Western Medicine, Telemedicine, Chronic Disease Management

Shanxi Bethune Hospital

Not applicable

10,000

Taiyuan

2025-11-01

By invitation

AI-Assisted Pathologist Performance Improvement: A Multicenter, Prospective, Randomized Controlled Trial

NCT07291362Pathology Foundation Model

Nanfang Hospital, Southern Medical University

Not applicable

1,000

Guangzhou, Zhengzhou

2025-11-01

Recruiting

Novel CD19/BCMA Dual-Targeted CAR-T Cell Therapy for the Treatment of Relapsed/Refractory Multiple Myeloma

NCT07359014Relapse Multiple Myeloma

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

Hangzhou

2025-11-01

Not yet open

Dosimetric Differences and Clinical Significance Analysis Between Body Gamma Knife and VMAT Radiotherapy for Primary Liver Cance

NCT07211815Primary Liver Cancers

Chifeng Tumor Hospital

Observational

Chifeng

2025-11-01

Recruiting

Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell Lymphoma

NCT07270835Hemophagocytic Lymphohistiocytosis, B Cell Lymphoma

DrugsZanubrutinib·Rituximab

The First Affiliated Hospital of Soochow University

Phase 4

Suzhou

2025-11-01

Recruiting

Epunamin Combined With DECP for Relapsed/Refractory Multiple Myeloma

NCT07497165Relapsed/Refractory Multiple Myeloma (RRMM), Multiple Myeloma

Shanxi Bethune Hospital

Observational

Taiyuan

2025-11-01

By invitation

Retrospective Multicenter Study of Patient-level T1CE/FLAIR MRI Deep Learning to Predict EGFR/ALK Driver Status in NSCLC Brain Metastases With External Validation and Survival Analysis

NCT07373951Non-Small Cell Lung Cancer, Brain Metastases

Ming Yang

Observational

380

Beijing

2025-11-01

Not yet open

Postbiotics Ameliorate Cachexia in Patients With Non-small-cell Lung Cancer

NCT07185308Cachexia; Cancer

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Not applicable

150

Chongqing

2025-11-01

Recruiting

Multi-Omics-Based Prediction of Allograft Dysfunction After Lung Transplantation

NCT07243964Lung Diseases

Chang Chen

Observational

244

Shanghai

2025-11-01

Recruiting

The Efficacy of Specific Immunotherapy Guided by Component-Resolved Diagnosis for Dust Mite Allergens in Chinese Pediatric Patients With Rhinitis and/or Asthma

NCT07452380Allergic Rhinitis Due to House Dust Mite

The Children's Hospital of Zhejiang University School of Medicine

Observational

1,000

Hangzhou

2025-11-01

Recruiting

The Necessity of Surgery in Patients With mGC Achieving Radiological Response After Conversion Therapy

NCT07757165Advanced Metastatic Gastric Cancer

Fudan University

Phase 2

126

Shanghai

2025-11-01

Recruiting

The Efficacy and Safety of Fosrolapitant and Palonosetron Hydrochloride for Injection in Preventing Nausea and Vomiting Caused by Multi-cycle Immunotherapy and Chemotherapy in Patients With Esophageal Cancer and Lung Cancer

NCT07617246Esophagus Cancer, Lung Cancer

DrugFosrolapitant and Palonosetron Hydrochloride

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

120

Hangzhou

2025-11-01

Recruiting

A Study of Agalsidase Alfa Enyzme Replacement Therapy in Chinese Children and Adults With Fabry Disease

NCT07187440Fabry Disease

Takeda

Observational

200

Hefei, Beijing, Fuzhou, Hangzhou, Shantou, Shenzhen, Shijiazhuang, Harbin

2025-11-01

Recruiting

the Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Gastrointestinal Dysfunction After Urological Laparoscopic Surgery

NCT07133620Postoperative Gastrointestinal Dysfunction (POGD)

The First Affiliated Hospital of Xiamen University

Not applicable

112

Xiamen

2025-11-01

Recruiting

CONNEctome-guided Navigation for Eloquent-area Tumor Surgery Trial

NCT07657403Brain Neoplasms, Eloquent Area Brain Tumors

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Not applicable

200

Beijing

2025-11-01

Recruiting

Artificial Intelligence in Assessing Gastric Intestinal Metaplasia Via the EGGIM Score

NCT07257796Intestinal Metaplasia of Gastric Mucosa, Artificial Intelligence, Endoscopy

Qilu Hospital of Shandong University

Observational

3,000

Jinan

2025-11-01

Recruiting

New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer

NCT07559760Metastatic Colorectal Cancer

DrugsLevofolinic Acid·5 FU continuous

The First Hospital of Jilin University

Phase 2

Changchun

2025-11-01

Recruiting

Effect of OFA, OSA Versus Opioid-based Anesthesia on NETs and Cancer Cell Malignancy After Colorectal Cancer Surgery

NCT07264556Colorectal Cancer, Opioid-free Anesthesia, NETs

Fudan University

Not applicable

Shanghai

2025-11-01

Not yet open

RATME Vs LATME in Middle and Low Rectal Cancer

NCT06105203Total Mesorectal Excision, Rectal Neoplasms, Robotic Surgical Procedures, Laparoscopy

The First Hospital of Jilin University

Not applicable

1,026

Changchun

2025-11-01

Recruiting

Efficacy and Safety of Tranexamic Acid in Adult Liver Transplantation---ESTA Trial

NCT07157631Liver Transplantation, Tranexamic Acid, End-stage Liver Disease (ESLD)

DrugTranexamic Acid

RenJi Hospital

Not applicable

1,546

Shanghai

2025-11-01

Recruiting

One vs Three HIPEC Cycles After CRS for Pseudomyxoma Peritonei

NCT07328737Pseudomyxoma Peritonei

Beijing Tsinghua Chang Gung Hospital

Not applicable

132

Beijing

2025-11-01

Active, closed

Posterior Extra-fascial RARP in Intermediate or High Risk Prostate Cancer

NCT06434649Surgical Procedure, Unspecified, Prostate Cancer

Ning Xu

Not applicable

118

Fuzhou

2025-11-01

Recruiting

CAIX PET/ CT Guided Radiation Therapy in CcRCC.

NCT07540260Radiation Therapy, Metastatic Renal Cancer, Recurrent Renal Cell Cancer

Peking University First Hospital

Not applicable

Beijing

2025-11-01

Recruiting

Intensive Versus Conventional Blood Pressure Control Following Stroke Thrombectomy

NCT07350564Stroke

Hao Yonggang

Not applicable

910

Suzhou

2025-11-01

Recruiting

[18F]NIDF PET Imaging in Tau-related Diseases

NCT07306598Neurodegenerative Disease, Alzheimer s Disease, Tauopathies

Tianjin Medical University

Observational

Hefei, Qingdao, Tianjin

2025-11-01

Recruiting

Efficacy and Safety of Icaritin Combined With mFOLFOX in Postoperative HCC With High-risk Recurrence Factors

NCT07337460Hepatocellular Carcinoma (HCC)

Northern Jiangsu People's Hospital

Phase 2

Yangzhou

2025-11-01

By invitation

Efficacy and Safety of Temporal Interference Stimulation on Cognitive Function in Patients With Early-Stage Alzheimer's Disease

NCT07543094Alzheimer Disease

Ruijin Hospital

Not applicable

Shanghai

2025-11-01

Recruiting

Liposomal Irinotecan, Capecitabine and Enlonstobart With Short-Course Radiotherapy for Locally Advanced Rectal Cancer

NCT07281157Advanced Rectal Cancer

DrugShort-course radiotherapy

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2025-11-01

Not yet open

Effectiveness of Electrical Pudendal Nerve Stimulation for Neurogenic Lower Urinary Tract Dysfunction in Pediatric Tethered Cord Syndrome Post-Surgery

NCT07062133Postoperative Neurogenic Lower Urinary Tract Dysfunction Secondary to Tethered Cord Syndrome

Shanghai Institute of Acupuncture, Moxibustion and Meridian

Not applicable

Shanghai

2025-11-01

Active, closed

Clinical Outcomes and Immunotherapy in Lung Cancer With Pulmonary Fibrosis

NCT07396467Lung Cancer (Diagnosis), Pulmonary Fibrosis, Interstitial Lung Diseases

The First Affiliated Hospital with Nanjing Medical University

Observational

200

Nanjing

2025-11-01

Recruiting

Phase I/II Clinical Study of GT201 Injection as Monotherapy or in Combination With PD-1 Inhibitor for Advanced Solid Tumors

NCT06144671Advanced Solid Tumors

DrugsGT201·Aldesleukin

Grit Biotechnology

Phase 1/2

Shanghai, Chengdu

2025-11-01

Recruiting

An Exploratory Research on the Efficacy and Safety of Antibacterial Absorbable Dressing in Chronic Non-healing Wounds

NCT07261501Wound Heal, Wound Healing Delayed

Peking University Third Hospital

Not applicable

Beijing

2025-11-01

Recruiting

TAIC FOLFOX for Locally Advanced G/GEJA

NCT07655024Gastric Cancer (Diagnosis), Gastroesophageal Junction Adenocarcinoma

DrugFolfox

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Phase 2

Beijing

2025-11-01

Recruiting

Epidemiological Characteristics and Efficacy Evaluation of Difficult-To-Treat Crohn's Disease

NCT07364734Crohn Disease

Xiang Gao

Observational

1,400

Guangzhou

2025-11-01

By invitation

The Effect of Nurse-led Health Coaching on Blood Pressure Control and Disease Self-management Among Patients With Hypertension in Huayuan County, Western Hunan, China: a Randomized Controlled Trial

NCT07606768Hypertension (HTN)

The Third Xiangya Hospital of Central South University

Not applicable

Huayuan

2025-11-01

Recruiting

Nudge-Based Shared Decision Making and Self-Management in Type 2 Diabetes: A Randomized Trial

NCT07129915Diabetes Mellitus, Type 2, Physician-Patient Relations, Self-management

Yunxuan Li

Not applicable

250

Xiamen

2025-11-01

Recruiting

Radiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC

NCT07291401Rectal Cancer Patients

Zhongnan Hospital

Phase 2

108

Wuhan

2025-11-01

Recruiting

Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental Disorders

NCT07479758Major Depressive Disorder (MDD), Schizophrenia, Bipolar Disorder, Severe Mental Disorders

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

320

Hangzhou

2025-11-01

By invitation

Nimotuzumab,Camrelizumab, and Neoadjuvant Chemotherapy（nCT） in the Treatment of Esophageal Squamous Cell Carcinoma

NCT07312578Esophageal Squamous Cell Carcinoma

DrugsAlbumin paclitaxel·Nimotuzumab·Camrelizumab·Cisplatin

Peking University

Phase 2

Beijing

2025-11-01

Not yet open

A Phase II Clinical Study Evaluating SSGJ-706 in Combination Therapy for Advanced Gastrointestinal Cancers

NCT07233850Gastric/Gastroesophageal Junction Adenocarcinoma, Metastatic Colorectal Cancer (CRC), Pancreatic Ductal Adenocarcinoma (PDAC), Oesophageal Cancer

DrugsSSGJ-706·Xelox·Bevacizumab

Shenyang Sunshine Pharmaceutical Co., LTD.

Phase 2

300

Wuhan

2025-11

Not yet open

Open-Label, Biomarker-Integrated Umbrella Trial for First-Line Treatment of Extensive-stage Small Cell Lung Cancer

NCT07172412Extensive Stage Lung Small Cell Cancer

DrugsCisplatin/Carboplatin·Selinexor·Anlotinib·Etoposide

Tianjin Medical University Cancer Institute and Hospital

Phase 2

165

Tianjin

2025-11

Not yet open

Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

NCT06468436Aged, Intensive Care Units, Ventilators, Mechanical, Dexmedetomidine

DrugsDexmedetomidine-esketamine combination·Dexmedetomidine

Peking University First Hospital

Not applicable

1,508

Beijing, Tianjin

2025-11

Not yet open

Sacubitril/Allisartan for Hypertensive Patients With Overweight or Obesity

NCT07241338Hypertension

DrugAmlodipine

Jing Liu

Phase 4

104

Beijing

2025-11

Not yet open

A Phase III Study of NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients

NCT07177859Paroxysmal Nocturnal Hemoglobinuria

DrugsNTQ5082·Eculizumab

Nanjing Chia-tai Tianqing Pharmaceutical

Phase 3

Tianjin

2025-11

Not yet open

Fengliao Changweikang for Diarrhea-predominant Irritable Bowel Syndrome: N-of-1 Trial

NCT07061184Irritable Bowel Syndrome - Diarrhoea, Traditional Chinese Medicine (TCM), N of 1 Study Design, Efficacy and Safety

Peking Union Medical College Hospital

Phase 4

Beijing

2025-11

Recruiting

AD-SVF Therapy for Refractory Endometrial Infertility

NCT07230600Endometrium; Atrophy, Intrauterine Synechiae

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 1

Nanjing

2025-11

Recruiting

Non-Invasive Fundus Retinal Detection Technology for Early Diagnosis of Parkinson's Disease

NCT07244640Parkinson's Disease (PD)

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

200

Hangzhou

2025-11

Recruiting

Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE

NCT07233642Systemic Lupus Erythematosus

The Children's Hospital of Zhejiang University School of Medicine

Phase 1

Hangzhou

2025-11

Not yet open

A Clinical Study Evaluating the Safety, Tolerability, Preliminary Efficacy and Immunogenicity of a Tumor Vaccine Injection Targeting Stressinducible Proteins MICA/B in Combination With the AG Regimen in Patients With Metastatic Pancreatic Cancer

NCT07231094Pancreatic Cancer Metastatic

The Third Xiangya Hospital of Central South University

Early Phase 1

Hunan

2025-11

Not yet open

A Trial of SHR-4658 in Healthy Volunteers or Volunteers With Elevated Blood Pressure

NCT07230145Heart Failure

Beijing Suncadia Pharmaceuticals Co., Ltd

Phase 1

Beijing

2025-11

Not yet open

Evaluation of the Efficacy and Safety of TQB2825 Injection Compared to Immunotherapy in the Treatment of Recurrent/Refractory Follicular Lymphoma

NCT07187960Follicular Lymphoma

DrugsTQB2825·Rituximab

Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.

Phase 3

228

Beijing, Chongqing, Lanzhou, Guangzhou, Guiyang, Haikou, Harbin, Zhengzhou

2025-11

Recruiting

A Digitally-Enabled System for Precision Assessment and Intervention of Disability Risk in Older Adults

NCT07508813Disability

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

238

Hangzhou

2025-10-31

Recruiting

To Evaluate The Safety and Efficacy of STSA-1002 Injection in Patients With Acute Respiratory Distress Syndrome

NCT07208591Acute Respiratory Distress Syndrome (ARDS)

Staidson (Beijing) Biopharmaceuticals Co., Ltd

Phase 3

406

Beijing, Xiamen, Guangzhou, Zunyi, Luoyang, Zhengzhou, Wuhan, Xiangtan

2025-10-31

Recruiting

A Clinical Trial of SIBP-A10 Injection in the Treatment of Advanced Malignant Tumor Subjects.

NCT07205198Advanced Tumors

Shanghai Institute Of Biological Products

Phase 1

160

Dalian

2025-10-31

Recruiting

Postoperative Delirium in Patients Undergoing Cardiac Surgery

NCT07239648Postoperative Delirium

Xijing Hospital

Observational

1,500

Xi'an

2025-10-31

Recruiting

Prevention of Delayed CINV After Autologous Transplant: Olanzapine-Containing Regimen vs. Dexamethasone-Containing Regimen

NCT07413809Multiple Myeloma

DrugsFosaprepitant·Olanzapine·Dexamethasone

The Affiliated People's Hospital of Ningbo University

Phase 3

Ningbo

2025-10-31

Recruiting

Efficacy and Safety Phase II Study of VC005 Tablets in Subjects With Non-segmental Vitiligo

NCT07172347Non-segmental Vitiligo

DrugVC005

Jiangsu vcare pharmaceutical technology co., LTD

Phase 2

120

Beijing

2025-10-31

Recruiting

A Study of AND017 to Evaluate Efficacy and Safety in Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Patients With Anemia

NCT07494409Anemia Due to Chronic Kidney Disease

DrugAND017

Kind Pharmaceuticals LLC

Phase 3

300

Shanghai

2025-10-31

Recruiting

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

NCT07223593Peripheral Arterial Disease

DrugOrforglipron

Eli Lilly and Company

Phase 3

1,205

Beijing, Chengdu, Guangzhou, Harbin, Luoyang Shi, Nanjing, Shanghai, Tianjin

2025-10-31

Recruiting

Camrelizumab and Apatinib With or Without FOLFOX Chemotherapy for Advanced HCC

NCT07267806Hepato Cellular Carcinoma (HCC), Chemotherapy Effect

DrugCamrelizumab and apatinib

Linhui Peng

Phase 3

326

Guangzhou

2025-10-31

Recruiting

Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLC

NCT07110103SCLC, SCLC, Extensive Stage

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 2

Beijing, Chongqing

2025-10-31

Not yet open

The Effects of Clostridium Butyricum on Adverse Events During Adjuvant Chemotherapy for Colorectal Cancer

NCT07152886Colorectal Cancer, Chemotherapeutic Toxicity

DrugClostridium butyricum

The Affiliated Hospital of Qingdao University

Phase 4

238

Qingdao

2025-10-31

Recruiting

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

NCT07291037Non-small Cell Lung Cancer (NSCLC)

DrugsDato-DXd·Docetaxel

AstraZeneca

Phase 3

400

Beijing, Changchun, Changsha, Chengdu, Chongqing, Fuzhou, Guangzhou, Hangzhou

2025-10-31

Recruiting

Evaluation of the Safety and Effectiveness of CHORDS® Cerebral Protection System During TAVR: DUET Trial

NCT07648693Transcatheter Aortic Valve Replacement (TAVR), Cerebral Vascular Accident (CVA)/Stroke

Resonova (Shanghai) Medtech Limited

Not applicable

240

Bengbu, Hefei, Beijing, Chongqing, Fuzhou, Guangzhou, Nanchang, Qingdao

2025-10-31

Recruiting

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

NCT07205822Breast Cancer

DrugDato-DXd

AstraZeneca

Phase 3

100

Beijing, Changsha, Guangzhou, Linyi, Shandong, Wuhan, Zhengzhou

2025-10-30

Not yet open

An Exploratory Study of Golidocitinib in Adult Patients With ITP

NCT07196163Immune Thrombocytopenia (ITP)

DrugGolidocitinib

Peking University People's Hospital

Phase 1/2

138

Beijing

2025-10-30

Not yet open

A Clinical Study to Explore CT1194D in Patients With Relapsed/Refractory B-Cell Neoplasms

NCT07200479Relapsed/Refractory B-Cell Neoplasms

Institute of Hematology & Blood Diseases Hospital, China

Phase 1

Tianjin

2025-10-30

Not yet open

An Exploratory Study of Near-infrared Light Therapy for Mild to Moderate Alzheimer's Disease

NCT06836180Alzheimer Disease

Xuanwu Hospital, Beijing

Early Phase 1

Beijing

2025-10-30

Recruiting

Dynamic Airway Resistance & ML: Guide Sputum Suction in Ventilated Patients

NCT07375667Mechanical Ventilation Pressure High, Ventilator-Associated Pneumonia (VAP), Respiratory Depression Neonatal

Affiliated Hospital of Nantong University

Not applicable

258

Bengbu, Beijing, Hangzhou

2025-10-30

Recruiting

F182112 Phase Ib Clinical Study for the Treatment of Patients With Systemic Lupus Erythematosus

NCT07829614Systemic Lupus Erythematosus (SLE)

DrugPomalidomide

Shandong New Time Pharmaceutical Co., LTD

Phase 1

Shanghai

2025-10-30

Not yet open

A Prospective, Single-center, Phase II Study of Sacituzumab Tirumotecan in Combination With Pembrolizumab for Neoadjuvant Treatment of Triple-Negative Breast Cancer (TNBC)

NCT07054242Neoadjuvant Therapy, Stage II to III (T1cN1-2 or T2-4N0-2) TNBC Breast Cancer

DrugsSacituzumab tirumotecan·Pembrolizumab

Yantai Yuhuangding Hospital

Phase 2

Yantai

2025-10-30

Active, closed

Serplulimab, Chidamide, and Rituximab Followed by Sequential R-CHOP for Newly Diagnosed Elderly MYC/BCL2 Double-Expressor DLBCL

NCT07538180Newly Diagnosed MYC/BCL2 Double-expressor DLBCL

Sun Yat-sen University

Phase 2

Guangzhou

2025-10-30

Recruiting

A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

NCT07219615Chronic Spontaneous Urticaria

DrugsLitfulo·Ritlecitinib

Pfizer

Phase 2

200

Beijing, Guangzhou, Shijiazhuang, Shanghai, Tianjin, Hangzhou

2025-10-30

Recruiting

A Study to Evaluate the Efficacy and Safety of Different Doses of CB03-154 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT07082192ALS (Amyotrophic Lateral Sclerosis)

Shanghai Zhimeng Biopharma, Inc.

Phase 2/3

240

Beijing

2025-10-30

Recruiting

Auricular Stimulation for Functional Dyspepsia With Insomnia: Efficacy and Mechanisms

NCT07442734Functional Dyspepsia, Insomnia, Brain and Nervous System

The First Affiliated Hospital of Zhejiang Chinese Medical University

Not applicable

176

Hangzhou

2025-10-30

Not yet open

A Prospective，Single Arm, Multicenter Clinical Study of BTLA Monoclonal Antibody JS004 (B/T Lymphocyte Attenuator Factor Monoclonal Antibody) in Combination With Toripalimab in Patients With Unresectable or Advanced Renal Cell Carcinoma Who Had Failed Previous Immunotherapy

NCT06730932Unresectable or Advanced Clear Cell Renal Cell Carcinoma That Has Progressed After Previous Immunotherapy

RenJi Hospital

Phase 2

Shanghai

2025-10-30

Recruiting

QL1706 Combined With Chemotherapy in the Treatment of Immune-mediated NSCLC

NCT07330596NSCLC (Advanced Non-small Cell Lung Cancer)

DrugLenvatinib

Anhui Provincial Cancer Hospital

Phase 2

Hefei

2025-10-30

Recruiting

Letermovir Prophylaxis Duration Guided by CMV-Specific T-cell Monitoring After Allo-HSCT.

NCT07569653Cytomegalovirus Infections, Cytomegalovirus Disease, Hematopoietic Stem Cell Transplantation, Graft vs Host Disease

WeiShi

Phase 4

120

Beijing, Shijiazhuang, Zhengzhou, Jingzhou, Wuhan, Hohhot, Nanchang, Wenzhou

2025-10-30

Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

NCT07173751Breast Neoplasms

DrugsEribulin·Pumitamig·Gemcitabine·Carboplatin

BioNTech SE

Phase 3

558

Changde, Harbin, Hefei, Jinan, Lanzhou, Linyi, Nanchang, Nanjing

2025-10-30

Active, closed

A Study of SHR-A2009 Combined With Aumolertinib Versus Aumolertinib for First-line Treatment in EGFR-mutated, Advanced or Metastatic NSCLC

NCT07183189Non-small Cell Lung Cancer

DrugsSHR-A2009·Almonertinib

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 3

582

Guangzhou

2025-10-30

Recruiting

Adebrelimab With Famitinib and Chemotherapy as Neoadjuvant Therapy for ESCC

NCT07796113Esophageal Squamous Cell Carcinoma

DrugsFamitinib·Adebrelimab

First Affiliated Hospital Xi'an Jiaotong University

Phase 2

Xi'an

2025-10-30

By invitation

A Single-Arm Study on the Efficacy of Sequential Chemoradiotherapy Followed by Surgery in Adult Nasal and Paranasal Sinus Rhabdomyosarcoma

NCT07449949ORR, PFS, OS

Eye & ENT Hospital of Fudan University

Observational

Shanghai

2025-10-30

By invitation

Comparison of Accuracy of Full-arch Implant Digital and Conventional Impressions.

NCT07190820Edentulous Jaw

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Not applicable

Shanghai

2025-10-30

Recruiting

A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis

NCT07201051Bronchiectasis

DrugGSK3862995B

GlaxoSmithKline

Phase 2

363

Beijing, Chongqing, Dongguan, Guangzhou, Guilin, Hangzhou, Huizhou, Jiangmen

2025-10-30

Recruiting

Impact of Airway Mucus Plugs on Secondary Pulmonary Fibrosis in COPD Patients: A Single-Center Case-Control Study

NCT07236541Lung Fibrosis

Ming Zhong

Observational

Shanghai

2025-10-30

Recruiting

BPC2001 for the Prevention of Acute Graft-Versus-Host Disease Following Haploidentical Stem Cell Transplantation

NCT07246031Graft -Versus-host-disease, aGVHD, Haploidentical Stem Cell Transplantation, cGVHD

BioPhoenix Co., Ltd.

Phase 2

Beijing, Wuhan

2025-10-29

Active, closed

A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus Given to Chinese Adults 18 to 59 Years of Age at Increased Risk of Respiratory Syncytial Virus Disease

NCT07220109Respiratory Syncytial Virus Infections

DrugRSVPreF3 OA vaccine

GlaxoSmithKline

Phase 3

750

Beijing, Xiangtan, Nanjing, Chengdu, Chongqing, Guangzhou, Jiujiang, Kunming

2025-10-29

Recruiting

Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Trial to Evaluate the Efficacy and Safety of HRS-9813 in Subjects With Pulmonary Fibrosis

NCT07192939IPF and PPF

Guangdong Hengrui Pharmaceutical Co., Ltd

Phase 2

270

Beijing

2025-10-29

Recruiting

Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis

NCT07250269Relapsed/Refractory AL Amyloidosis

DrugAZD0120

Gracell Biotechnologies (Shanghai) Co., Ltd.

Phase 1

Beijing, Changchun, Guangzhou, Hangzhou, Suzhou, Wenzhou, Wuhan

2025-10-29

Recruiting

A Study of YL201 and Ivonescimab (AK112) in Advanced Solid Tumors

NCT07208773Advanced Solid Tumors, Non Small Cell Lung Cancer, Small Cell Lung Cancer

DrugsTam-Peli·Ivonescimab

MediLink Therapeutics (Suzhou) Co., Ltd.

Phase 1/2

260

Guangzhou

2025-10-29

Recruiting

A Study of Ivonescimab in First-Line ES-SCLC

NCT07245446Extensive-stage Small Cell Lung Cancer (ES-SCLC)

DrugsLigufalimab·Cadonilimab·Ivonescimab·Etoposide

Akeso

Phase 2

180

Beijing, Xi'an, Shanghai

2025-10-29

Active, closed

Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a)

NCT07327840Lipoprotein Disorder

Kylonova (Xiamen) Biopharma co., LTD.

Phase 2

204

Beijing, Baotou, Changde, Chongqing, Dali, Daqing, Guangzhou, Harbin

2025-10-29

Recruiting

GT719 Injection for Moderate to Severe Refractory Autoimmune Disease

NCT07132112Auto Immune Disease

DrugGT719

Grit Biotechnology

Early Phase 1

Nantong

2025-10-28

Recruiting

Safety and Efficacy of ZZSW-01 in Relapsed/Refractory B-cell Malignancies

NCT07240974Relapsed/Refractory B-cell Malignancies

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Early Phase 1

Wuhan

2025-10-28

Recruiting

Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment

NCT07139366Gastritis, Dyspepsia, Helicobacter Pylori Infection, Gastric Cancer

DrugsSaccharomyces boulardii·Bismuth·Tetracycline·Esomeprazole

Yongquan Shi

Phase 4

1,248

Xi'an

2025-10-28

By invitation

To Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Food Effects of LY03021 in Healthy Chinese Subjects

NCT07371065Major Depressive Disorder

Luye Pharma Group Ltd.

Phase 1

Shanghai

2025-10-28

Recruiting

Clinical Study of O&D-001 Injection in the Treatment of Relapsed or Refractory Multiple Myeloma

NCT07369895Relapsed or Refractory Multiple Myeloma

O&D BioTech Group CO., Limited

Phase 1

Guangzhou

2025-10-28

Recruiting

Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I NSCLC

NCT07120282Lung Cancer (NSCLC)

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 2

108

Beijing

2025-10-28

Recruiting

A Study of HRS-4508 in Combination With Other Anti-tumor Therapy for Solid Tumor

NCT07140393Solid Tumor

DrugsHRS-4508·Trastuzumab Rezetecan·Pertuzumab·Trastuzumab

Jiangsu HengRui Medicine Co., Ltd.

Phase 1/2

120

Beijing

2025-10-28

Recruiting

QL1706 Plus Chemotherapy as Neoadjuvant Therapy for Locally Advanced Cervical Cancer: A Phase II Trial

NCT07286253Neoadjuvant Treatment for Locally Advanced Cervical Cancer

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Phase 2

Guangzhou

2025-10-28

Recruiting

A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation

NCT07217067Atrial Fibrillation

DrugPKN605

Novartis Pharmaceuticals

Phase 2

165

Beijing, Xi'an

2025-10-28

Active, closed

Research on the Effectiveness of Remote Rehabilitation l for Shoulder and Neck Recovery in Oral Cancer Patients After Selective Neck Dissection

NCT07504809Oral Cancer Patients After Selective Neck Dissection

Pai Pang

Not applicable

Shenyang

2025-10-28

Recruiting

Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients

NCT07271849Postoperative Pain, Acute, Hemodynamics, Total Knee Arthroplasty (TKA)

Qianfoshan Hospital

Phase 4

162

Jinan

2025-10-28

Recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GB18 Injection in Healthy Participants

NCT07237464Cancer Cachexia (CC), Cancer Cachexia, Cancer Cachexia Syndrome

DrugGB18

Shenzhen Kexing Pharmaceutical Co., Ltd.

Phase 1

Beijing

2025-10-28

Recruiting

Population Pharmacokinetics and Pharmacodynamics of Ciprofol

NCT07301242Hip Fractures (ICD-10 72.01-72.2), Osteoarthritis, Knee and Hip, Femoral Neck Fractures

DrugCiprofol

Shanghai Geriatric Medical Center

Observational

Shanghai

2025-10-28

Recruiting

Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis

NCT07263425Leptomeningeal Metastasis of HER2-positive Breast Cancer

DrugAdministration of Thiotepa

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2025-10-27

Recruiting

Confirmatory Clinical Study of HEC585 Tablets in Patients With IPF

NCT07082842Idiopathic Pulmonary Fibrosis (IPF)

DrugsHEC585·Pirfenidone

Sunshine Lake Pharma Co., Ltd.

Phase 3

472

Beijing

2025-10-27

Recruiting

SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer

NCT07162714Rectal Cancer, Radiation, AK112

DrugIvonescimab

Zhejiang Cancer Hospital

Phase 2

Hangzhou

2025-10-27

Active, closed

A Phase Ⅰ b Clinical Study of ART101 Injection

NCT07614308Hypertension (HTN)

Arnatar Therapeutics, Inc.

Phase 1

Suzhou

2025-10-27

Active, closed

A Translational Study for Phenotyping and Endotyping Chinese Patients With NCFBE

NCT07245407Non-cystic Fibrosis Bronchiectasis

AstraZeneca

Observational

251

Beijing, Chongqing, Quanzhou, Lanzhou, Shenzhen, Zhanjiang, Nanning, Guiyang

2025-10-27

Recruiting

UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis

NCT07109986Systemic Lupus Erythematosus, Lupus Nephritis

Nanjing IASO Biotechnology Co., Ltd.

Phase 1

Nanjing

2025-10-27

Recruiting

A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combined With Chemotherapy in Lung Cancer

NCT07381829Advanced Solid Tumor Cancer

DrugsHC010·Ivonescimab·Etoposide·Pemetrexed

HC Biopharma Inc.

Phase 1

328

Guangzhou

2025-10-27

Not yet open

A Phase 2 Study to Evaluate the Efficacy, Safety of SIM0278 in Subjects With Moderate to Severe Atopic Dermatitis

NCT07175233Atopic Dermatitis (AD)

DrugSIM0278

Jiangsu Simcere Pharmaceutical Co., Ltd.

Phase 2

184

Hangzhou, Shenyang

2025-10-27

Active, closed

Organotypic Platform for Therapeutic Investigation (OPTin) for Guiding Cancer Patients Treatment

NCT07468422Cancer Patients With Solid Tumors, Cancer (Advanced Stage)

China Medical University Hospital

Observational

200

2025-10-27

Recruiting

Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection

NCT06968806Aortic Dissection, Inflammation

DrugKetorolac

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 3

1,346

Nanjing

2025-10-27

Recruiting

A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis.

NCT07641634Healthy Volunteers, Systemic Sclerosis (SSc), Scleroderma, Systemic, Scleroderma

Prolium Bioscience, Inc

Phase 1/2

Beijing, Guangzhou, Henan, Nanchang, Nanjing, Pingxiang

2025-10-27

Recruiting

Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study

NCT07621445Diabetes Mellitus, Diabetes Mellitus, Type 1

Second Xiangya Hospital of Central South University

Observational

2,950

Changsha

2025-10-27

Recruiting

A Clinical Study of BAT4406F Injection in Patients With Minimal Change Disease/Focal Segmental Glomerulosclerosis

NCT07499700Minimal Change Disease (MCD), Focal Segmental Glomerulosclerosis (FSGS)

DrugBAT4406F

Bio-Thera Solutions

Phase 2/3

192

Beijing

2025-10-26

Recruiting

Multimodal Deep Learning for Postoperative Liver Cancer Risk Stratification and Intervention

NCT07282184Hepotacellular Carcinoma

Tongji Hospital

Phase 1/2

144

Wuhan

2025-10-26

Recruiting

Stereotactic Thrombolysis With Tenecteplase for Supratentorial Intracerebral Hemorrhage

NCT07208097Intracerebral Haemorrhage, Minimally Invasive Treatment

Tongji Hospital

Not applicable

768

Anqing, Hefei, Suzhou, Guangzhou, Nanning, Bijie, Guiyang, Kaili

2025-10-25

Recruiting

Application Effects of Wrist-Ankle Acupuncture in Patients With Different Types of Pain Following Perianal Surgery

NCT07340307Wrist-Ankle Acupuncture

The Affiliated Hospital of Putian University

Not applicable

Putian

2025-10-25

Recruiting

RGL-270 + ICI in Advanced NSCLC

NCT07652125NSCLC

DrugRGL-270

Guangdong Association of Clinical Trials

Not applicable

Guangzhou

2025-10-25

Recruiting

Determination of the Effective Dose of a Single Intravenous Dose of Tegileridine Fumarate for Postoperative Analgesia After Orthopedic Surgery: A Up-and-Down Sequential Allocation Study

NCT07353996Postoperative Pain

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 4

180

Hanzhong

2025-10-25

Recruiting

Neoadjuvant Zanidatamab + Tislelizumab + Chemotherapy for Selective Bladder Preservation in HER2-Positive MIBC

NCT07296705Muscle Invasive Bladder Cancer (MIBC)

DrugsZanidatamab·Nab-paclitaxel·Tislelizumab·Gemcitabine

Fujian Medical University Union Hospital

Phase 2

Fuzhou, Putian, Quanzhou, Sanming, Xiamen, Zhangzhou, Nanchang, Jinan

2025-10-25

Recruiting

TrIal of Early Minimally Invasive Catheter Evacuation With Thrombolysis in IntraCerebral Hemorrhage

NCT07187687Intracerebral Hemorrhage

Xuanwu Hospital, Beijing

Not applicable

750

Guangdong, Baotou, Beijing, Bozhou, Changsha, Changzhi, Changzhou, Chifeng

2025-10-24

Recruiting

A Study of QLC5508 Combinations in Patients With Advanced Solid Tumors

NCT07256782Advanced Solid Tumor

DrugsQLC5508·Cisplatin/Carboplatin·Adrucil·Lenvatinib

Qilu Pharmaceutical Co., Ltd.

Phase 1/2

444

Shanghai

2025-10-24

Recruiting

A Phase II Study of SSGJ-706 Monotherapy and Combination Therapy in Advanced Non-Small Cell Lung Cancer（NSCLC） Patients

NCT07171606First-line Advanced NSCLC Patients

DrugsSSGJ-706·Pemetrexed/Carboplatin·Carboplatin/Paclitaxel

Shenyang Sunshine Pharmaceutical Co., LTD.

Phase 2

240

Shanghai

2025-10-24

Recruiting

Level I-II Axillary Irradiation in Breast Cancer With Sentinel-Node Macro-metastases

NCT07469267Breast Cancer, Radiotherapy

Fudan University

Not applicable

1,608

Guiyang, Shijiazhuang, Harbin, Wuhan, Changde, Changsha, Dalian, Jinan

2025-10-24

Recruiting

Functional Lung Avoidance Radiotherapy Guided by 4DCT Pulmonary Ventilation Function Imaging: A Prospective Single-arm Clinical Study

NCT07339644Lung Cancer (Including Metastatic Cancer), Radiation Pneumonitis, Radiation-induced Lung Injury

The Second Affiliated Hospital of Chongqing Medical University

Not applicable

100

Chongqing

2025-10-24

Recruiting

A Phase Ⅱ/Ⅲ Study of HRS-2129 for Postsurgical Pain Management in Abdominal Surgery

NCT07185594Postoperative Analgesia

DrugHRS-2129

Shandong Suncadia Medicine Co., Ltd.

Phase 2/3

360

Zhengzhou, Hangzhou

2025-10-24

Recruiting

Orelabrutinib as Consolidation and Maintenance Therapy in Treatment-Naïve MZL.

NCT07372365Marginal Zone Lymphoma (MZL)

The First Affiliated Hospital of Soochow University

Phase 2

Suzhou

2025-10-24

Active, closed

ClinicAL outComes of IntraVascular Lithotripsy Combined With Conventional Lesion Preparation in Patients With Moderate to Severe Coronary Artery Calcification

NCT07340294Coronary Artery Calcification, Calcific Coronary Arteriosclerosis

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

1,096

Nanchang, Shenyang, Hangzhou, Tianjin

2025-10-24

Recruiting

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

NCT06793215Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer

DrugsDivarasib·Pemetrexed·Cisplatin·Carboplatin

Hoffmann-La Roche

Phase 3

600

Hefei, Nanchang, Hangzhou, Beijing, Bengbu, Changsha, Chengdu, Guangzhou

2025-10-24

Recruiting

Combination of COMBO Endoscopy Oropharyngeal Airway and HFNC Oxygenation in Sedated Gastrointestinal Endoscopy for Morbidly Obese Patients

NCT07175155Hypoxemia, Esophageal Cancer, Morbidly Obese Patients, Gastric Cancer

Zhejiang University

Not applicable

410

Beijing, Jinjiang, Hangzhou, Lishui, Taizhou

2025-10-24

Recruiting

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

NCT06899126Non-small Cell Lung Cancer

DrugsTrastuzumab deruxtecan·Pemetrexed·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 3

686

Beijing, Changchun, Changsha, Chengdu, Chongqing, Guangzhou, Hangzhou, Harbin

2025-10-24

Active, closed

FARAPULSE™ Pulsed Field Ablation System

NCT06762717Paroxysmal AF

Boston Scientific Corporation

Observational

501

Beijing

2025-10-23

Recruiting

A Phase II, Multicenter, Randomized, Controlled Clinical Study Comparing the Efficacy and Safety of Sintilimab Plus SOX Versus SOX Alone as Adjuvant Therapy for PD-L1-Positive, Stage pN3 Gastric Cancer

NCT07263386Gastric Adenocarcinoma

DrugSintilimab

The First Affiliated Hospital with Nanjing Medical University

Phase 2

460

Nanjing

2025-10-23

Recruiting

JSKN022 in Subjects With Advanced Malignant Solid Tumors

NCT07292402Advanced Malignant Solid Tumors

Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Phase 1

225

Guangzhou

2025-10-23

Recruiting

A Study of QL1706 Combined With Chemotherapy Induction on Sequential Immunotherapy Consolidation in Patients With Limited-Stage Small Cell Lung Cancer After Chemoradiotherapy

NCT07091305Limited-stage Small Cell Lung Cancer (LS-SCLC), Chemoradiotherapy, Induction Therapy, Consolidation Immunotherapy

DrugLenvatinib

Shanghai Chest Hospital

Phase 2

Shanghai

2025-10-23

Active, closed

A Immunogenicity and Safety Trial of the Recombinant Zoster Vaccine （CHO Cell）, LYB004 in Adults Aged 40 Years and Older

NCT07311148Herpes Zoster (HZ), Shingles, VZV, Recombinant Zoster Vaccine

DrugAntigen and adjuvant of LYB004

Guangzhou Patronus Biotech Co., Ltd.

Phase 2

840

Hengyang

2025-10-23

Active, closed

A Trial of SHR-A1811 Compared to Other Antitumor Therapies as Neoadjuvant Treatments in Early-stage or Locally Advanced HER2-positive Breast Cancer

NCT07196774Early-stage or Locally Advanced HER2-positive Breast Cancer

DrugsTrastuzumab Rezetecan·Pertuzumab·Trastuzumab·Docetaxel

Jiangsu HengRui Medicine Co., Ltd.

Phase 3

740

Shenyang, Shanghai

2025-10-23

Active, closed

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

NCT07076121Pancreatic Ductal Adenocarcinoma

DrugsNavlimetostat·Abraxane·Nab-paclitaxel·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

470

Hefei, Beijing, Chongqing, Fuzhou, Guangzhou, Harbin, Luoyang, Zhengzhou

2025-10-23

Recruiting

PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma.

NCT07053072Liver Cancer

West China Hospital

Phase 1

Chengdu

2025-10-23

Recruiting

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

NCT07219173Asthma

DrugBrenipatide

Eli Lilly and Company

Phase 2

531

Baotou, Beijing, Chengdu, Chongqing, Hangzhou, Nanchang, Nanjing, Shanghai

2025-10-22

Recruiting

Safety and Feasibility of Sulforaphane to Promote Early Haematopoietic Recovery After Cord Blood Transplantation

NCT07297576ALL (Acute B-Lymphoblastic Leukemia), AML (Acute Myelogenous Leukemia, MDS (Myelodysplastic Syndrome)

Institute of Hematology & Blood Diseases Hospital, China

Not applicable

Tianjing

2025-10-22

Recruiting

68Ga-PFD3 PET Imaging for the Diagnosis and Evaluation of Small Cell Lung Cancer

NCT07508852SCLC, SCLC, Extensive Stage, SCLC, Limited Stage, Small Cell Lung Cancer

Peking University First Hospital

Phase 1/2

Beijing

2025-10-22

Recruiting

Phase III Clinical Trial of the Recombinant Respiratory Syncytial Virus Vaccine ( CHO Cell)

NCT07272434Respiratory Syncytial Virus (RSV)

DrugRecombinant Respiratory Syncytial Virus Vaccine

MAXVAX Biotechnology Limited Liability Company

Phase 3

25,000

Guangzhou, Shijiazhuang, Zhengzhou, Wuhan, Changsha, Xi'an, Jinan, Chengdu

2025-10-22

Recruiting

Neuroprotection Bundles For Comatose Survivors Following Cardiac Arrest

NCT06992843Cardiac Arrest, Post-cardiac Arrest Care

Xiangya Hospital of Central South University

Not applicable

1,008

Changsha

2025-10-22

Recruiting

Distribution Characteristics of Helicobacter Pylori

NCT07253948Helicobacter Pylori, Early Gastric Cancer

Jilin University

Observational

231

Changchun

2025-10-22

Recruiting

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

NCT07213804Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Neoplasm Metastasis

DrugsSofe-M·MIRV·Pegylated liposomal doxorubicin·Topotecan

Eli Lilly and Company

Phase 3

1,630

Beijing, Changchun, Changde, Changsha, Chengdu, Guangzhou, Hangzhou, Jinan

2025-10-22

Recruiting

The Research of Integrated Traditional Chinese and Western Medicine on Hypothalamic Amenorrhea

NCT07580950Functional Hypothalamic Amenorrhea

Peking Union Medical College Hospital

Phase 4

210

Beijing

2025-10-22

Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

NCT07213791Ovarian Neoplasms, Breast Neoplasms, Pancreatic Intraductal Neoplasms, Colorectal Neoplasms

Eli Lilly and Company

Phase 1

340

Shanghai

2025-10-22

Recruiting

A Study of AK138D1 in Advanced Malignant Tumors

NCT07281326Solid Cancer

DrugAK138D1

Akeso

Phase 1

200

Harbin

2025-10-22

Recruiting

A Study of JMKX005425 in Patients With MSI-H/dMMR Advanced Solid Tumors

NCT07208136Advanced Solid Tumors

Jemincare

Phase 1

102

Beijing

2025-10-22

Recruiting

To Evaluate the Efficacy of CT041 in Sequential Treatment After First-line Treatment of Advanced Gastric/Esophagogastric Junction Adenocarcinoma

NCT07179484Gastroesophageal Junction Adenocarcinoma

DrugCT041 autologous CAR T-cell

Beijing GoBroad Hospital

Observational

Beijing

2025-10-22

Active, closed

Development of a Pan-Cancer Screening Model Based on Blood Biomarkers

NCT07554157Neoplasms

Zhejiang Cancer Hospital

Observational

10,000,000

Hangzhou

2025-10-22

Recruiting

A Multicenter, Prospective, Randomized Controlled Study on EUS-Guided Precise Disconnection of Varices Versus Endoscopic Gastric Variceal Glue Injection for the Prevention of Gastric Variceal Bleeding.

NCT07532915Gastric Variceal

Nanfang Hospital, Southern Medical University

Not applicable

Guangzhou

2025-10-22

Recruiting

Phase III Study of SHR-8068 Combined With Adebrelimab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer

NCT07170995Advanced or Metastatic Non-small Cell Lung Cancer

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 3

460

Jinan

2025-10-22

Recruiting

The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line Treatment of RAS/BRAF Wild Type Unresectable Metastatic Colorectal Cancer

NCT07257653Colorectal Neoplasms, RAS, BRAF, Cetuximabβ

Zhejiang University

Phase 2

Hangzhou

2025-10-21

Recruiting

SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak

NCT07209787Rectal Cancer

Beijing Chao Yang Hospital

Phase 4

966

Beijing

2025-10-21

Recruiting

Phase I Study of CPD704 Inhalation Suspension in Healthy Subjects

NCT07301203Healthy, Healthy Participants

Beijing Tide Pharmaceutical Co., Ltd

Phase 1

Beijing

2025-10-21

Active, closed

A Study of HRS-5632 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

NCT07185776Lipoprotein Disorder

Fujian Shengdi Pharmaceutical Co., Ltd.

Phase 2

203

Xi’an

2025-10-21

Recruiting

A Study to Evaluate Effectiveness and Safety of a TYK2 Inhibitor in Subjects With Moderate to Severe Plaque Psoriasis

NCT07234591Plaque Psoriasis, Moderate to Severe Plaque Psoriasis

Usynova Pharmaceuticals Ltd.

Not applicable

140

Shanghai

2025-10-21

Active, closed

A Study to Evaluate the Immunogenicity and Safety of a Recombinant Respiratory Syncytial Virus Vaccine in Older Adults Aged 60 Years and Older

NCT07208461Respiratory Syncytial Virus Infection Prevention

Guangzhou Patronus Biotech Co., Ltd.

Phase 2

700

Dangyang

2025-10-21

Recruiting

Intravenous rhTNK-tPA Before Stroke Thrombectomy in the Extended Time Window

NCT06987305Stroke, Acute Ischemic

DrugsRhTNK-tPA·Tenecteplase

Xinqiao Hospital of Chongqing

Phase 3

820

Wuhan, Xiangtan, Jiujiang, Nanchang

2025-10-21

Recruiting

Complex Arrhythmia Registry

NCT07024927Atrial Fibrillation (AF), Ventricular Tachycardia (VT)

Beijing Anzhen Hospital

Observational

4,000

Beijing

2025-10-21

Not yet open

Development and Validation of a Risk Prediction Model for Ischemic Stroke in Acute Myocardial Infarction Without Comorbid Atrial Fibrillation

NCT07171892Myocardial Infarction

First Affiliated Hospital of Ningbo University

Observational

4,000

Ningbo

2025-10-21

Recruiting

Awareness, Knowledge and Behavioral Seeking of Gynaecological Problems

NCT07208383Gynecologic Disease

Chinese University of Hong Kong

Observational

800

Hong Kong

2025-10-21

Recruiting

A Study of GFH375 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors Harboring KRAS G12D Mutation

NCT07259590Advanced Solid Tumors Cancer, PDAC, CRC (Colorectal Cancer)

Genfleet Therapeutics (Shanghai) Inc.

Phase 1/2

126

Beijing, Guangzhou, Zhengzhou, Wuhan

2025-10-21

Recruiting

Comparison of Underdilated Versus Standard TIPS in Preventing Variceal Rebleeding in Patients With Cirrhosis

NCT07253389Liver Cirrhosis, Gastroesophageal Varices Bleeding

Air Force Military Medical University, China

Not applicable

648

Xi'an

2025-10-20

Active, closed

A Study on the Safety and Clinical Efficacy of Guominkang in the Treatment of Diabetic Kidney Disease

NCT07907965Diabetic Kidney Disease (DKD), Type 2 Diabetes, Albuminuria

Beijing University of Chinese Medicine

Phase 2

Changzhi

2025-10-20

Recruiting

KD Treatment for Super-refractory Status Epilepticus

NCT07496749Super-refractory Status Epilepticus

Xuanwu Hospital, Beijing

Not applicable

Hefei, Beijing, Fuzhou, Nanning, Guiyang, Haikou, Shijiazhuang, Harbin

2025-10-20

Recruiting

Personalized iTBS in Real-World Clinical Settings for Schizophrenia

NCT07176468Schizophrenia, Transcranial Magnetic Stimulation

Anhui Medical University

Not applicable

Hefei

2025-10-20

Recruiting

PD-L1 Inhibitor Rechallenge After Immunotherapy-Related Pneumonitis in Patients With Lung Cancer

NCT07775820Lung Cancer, Rechallenge, Checkpoint Inhibitor Pneumonitis

Nanfang Hospital, Southern Medical University

Observational

150

Guangzhou, Shenzhen, Nanchang, Wenzhou

2025-10-20

Active, closed

Pharmacokinetic and Safety Study of GZR4 Injection in Subjects With Hepatic Impairment

NCT07193147Diabetes

DrugDegludec

Gan & Lee Pharmaceuticals.

Phase 1

Linyi

2025-10-20

Recruiting

Risk Factors Affecting MSC Efficacy in ACLF Patients

NCT07198854Acute-On-Chronic Liver Failure

Sun Yat-sen University

Observational

446

Guangzhou

2025-10-20

Recruiting

Haplo-Cord HSCT for AML/MDS

NCT07588360MDS (Myelodysplastic Syndrome), AML (Acute Myeloid Leukemia)

Fujian Medical University Union Hospital

Not applicable

Fuzhou, Guangzhou, Chengdu, Beijing

2025-10-20

Active, closed

Multicenter Study to Develop a Model to Identify Uric Acid Urinary Tract Stones Using CT and Lab Tests

NCT07328932Urinary Tract Stones

Jian Zhuo

Observational

1,650

Shanghai

2025-10-20

Recruiting

Evaluation of the Clinical Outcomes of the Embolic Protection System in Preventing Distal Embolism During Femoropopliteal Debulking Procedures

NCT07282301Femoropopliteal Disease

RenJi Hospital

Observational

150

Shanghai

2025-10-20

Recruiting

Association of Biomarkers and Gastric Antral Motility Index With Feeding Intolerance in Critically Ill Patients

NCT07178626Critically Ill Patients Who Are Not Allowed to Eat Orally But Can Initiate Enteral Nutrition Within 48 Hours of ICU

The First Hospital of Jilin University

Observational

160

Changchun

2025-10-20

Recruiting

Testing if PDR-001 Can Safely and Effectively Remove Harmful Brain Protein in Parkinson's Disease

NCT07157345Parkinson Disease (PD)

DrugSpartalizumab

Ruijin Hospital

Phase 1

Shanghai

2025-10-20

Recruiting

The Efficacy and Safety of Pregabalin Combined With Toludesvenlafaxine in Patients With Fibromyalgia

NCT07208357Fibromyalgia, Pregabalin, Duloxetine, Pain

DrugPregabalin

Beijing Tiantan Hospital

Not applicable

384

Beijing

2025-10-20

Recruiting

Desflurane vs. Propofol for Cardiac Anesthesia

NCT07116733Cardiac Surgery, Coronary Artery Bypass Grafting

Xijing Hospital

Phase 3

3,560

Fuzhou, Cangzhou, Shijiazhuang, Zhengzhou, Wuhan, Nanjin, Xi'an, Chengdu

2025-10-20

Recruiting

T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis

NCT07150208Breast Cancer With Brain Metastasis, HER2-low Expressing Breast Cancer

DrugsHLX04·Trastuzumab deruxtecan·Bevacizumab

Fudan University

Phase 2

140

Shanghai

2025-10-20

Not yet open

Multi-omics Study of Peritoneal Dialysis Effluent to Explore Biomarkers of Peritoneal Fibrosis

NCT07208513Peritoneal Dialysis, Peritoneal Fibrosis

Shanghai Jiao Tong University School of Medicine

Observational

Shanghai

2025-10-20

Recruiting

eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

NCT07177339Pulmonary Disease, Chronic Obstructive

DrugDepemokimab

GlaxoSmithKline

Phase 3

1,196

Shapingba, Nanning, Chengdu, Suining, Beijing, Changchun, Changsha, Chongqing

2025-10-20

Recruiting

Surgical Total Clearance Versus Extrahepatic Bile Duct Preservation for Biliary Tract Malignancies: A Single-Center, Randomized, Two-Arm, Prospective Phase II Clinical Trial

NCT07609641BTC

Tianjin Medical University Cancer Institute and Hospital

Not applicable

Tianjin

2025-10-20

Recruiting

An Open-label, Single-arm, Multicenter Exploratory Study of Adebrelimab Combined With Gemcitabine and Albumin-bound Paclitaxel as First-line Treatment for Biliary Tract Malignancies

NCT07668453Biliary Tract Neoplasms

DrugsAlbumin-Bound Paclitaxel /nab-Paclitaxel·Adebrelimab·Gemcitabine

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2025-10-20

Recruiting

A Sitting Tai Chi Programme for Chronic Stroke Survivors With Post-stroke Cognitive Impairment

NCT07512739Stroke, Cognitive Impairment

Chinese University of Hong Kong

Not applicable

176

Kunming

2025-10-20

Recruiting

Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement

NCT07104604Rectal Cancer

DrugsLiposomal Irinotecan·Tislelizumab·Capecitabine

Affiliated Cancer Hospital of Shantou University Medical College

Phase 2

Shantou

2025-10-20

Recruiting

The Efficacy of Sequential Treatment With Bevacizumab Combined With Atezolizumab in Advanced Liver Cancer With MASLD

NCT07285850HCC - Hepatocellular Carcinoma

DrugAtezolizumab

Eastern Hepatobiliary Surgery Hospital

Phase 2/3

Shanghai

2025-10-20

Recruiting

A Prospective Study on the Diagnosis of Malignant Tumors With 18F-FGIn PET/CT

NCT07602569Cancer (With or Without Metastasis)

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Observational

110

Guangzhou

2025-10-20

Recruiting

Early Application of Budesonide Enteric-coated Capsules in the Treatment of Primary IgA Nephropathy.

NCT07585981IgA Glomerulonephritis

DrugNefecon

Chinese PLA General Hospital

Observational

Beijing

2025-10-20

Recruiting

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 02(BTC&HCC)]

NCT07111546Advanced Solid Tumour

DrugsLBL-024·Gemcitabine·Bevacizumab·Cisplatin

Nanjing Leads Biolabs Co.,Ltd

Phase 2

140

Hefei, Fuzhou, Guangzhou, Nanning, Harbin, Zhengzhou, Xiangyang, Changsha

2025-10-20

By invitation

A Phase II Clinical Study to Evaluate the Efficacy and Safety of NS-136 in the Treatment of Schizophrenia

NCT07521683Schizophrenia(Acute)

DrugNS-136

NeuShen Therapeutics

Phase 2

150

Shanghai

2025-10-20

By invitation

Compare the Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of SAL023 and Italy-Manufactured Evenity in Healthy Subjects

NCT07384104Osteoporosis

DrugRomosozumab

Shenzhen Salubris Pharmaceuticals Co., Ltd.

Phase 1

118

Hefei

2025-10-19

By invitation

An Exploratory Clinical Study Evaluating Allogeneic iPSC-derived Pancreatic Islet Cells (CRG-002) for the Treatment of Diabetic Patients With Hypoglycemia Unawareness or Severe Hypoglycemic Events

NCT07503028T1DM - Type 1 Diabetes Mellitus, Pancreatogenic Diabetes Mellitus

Celregen Therapeutics

Early Phase 1

Hefei

2025-10-17

Recruiting

Iparomlimab and Tuvonralimab Combined With Nimotuzumab in Recurrent or Metastatic NPC After First-line Treatment Failure: A Single-arm Phase IIa Clinical Trial

NCT07101744Nasopharyngeal Carcinoma (NPC), First-line Treatment Failure Nasopharyngeal Carcinoma

DrugIparomlimab and Tuvonralimab

Sun Yat-sen University

Phase 2

Guangdong

2025-10-17

Recruiting

A Phase IIIb Clinical Study to Assess the Efficacy and Safety of GZR4 in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin

NCT07165223Diabetes

DrugDegludec

Gan & Lee Pharmaceuticals.

Phase 3

300

Linyi

2025-10-17

Recruiting

Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression

NCT05465252Age-Related Macular Degeneration

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Not applicable

Shanghai

2025-10-17

Recruiting

A Phase III Clinical Study of Adebrelimab Combined With Concurrent Chemoradiotherapy Versus Placebo Combined With Concurrent Chemoradiotherapy for the Treatment of Locally Advanced Cervical Cancer

NCT07168200Advanced Cervical Cancer

DrugsAdebrelimab·Paclitaxel·Cisplatin·Carboplatin

Shanghai Shengdi Pharmaceutical Co., Ltd

Phase 3

720

Shanghai

2025-10-17

Recruiting

Venetoclax in Combination With Ivosidenib and Azacitidine for Newly Diagnosed IDH1-Mutated AML

NCT06611839AML, IDH1 Mutation, Treatment

Institute of Hematology & Blood Diseases Hospital, China

Phase 1/2

Tianjin

2025-10-17

Recruiting

A Phase 2 Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of HRS-7085 Tablets in Patients With Inflammatory Bowel Disease

NCT07229950Adult Patients With Moderately to Severely Active Ulcerative Colitis

Shandong Suncadia Medicine Co., Ltd.

Phase 2

Chengdu

2025-10-17

Recruiting

A Study to Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLC

NCT07206498Non Small Cell Lung Cancer (NSCLC)

DrugsWSD0922-FU·Tagrisso·Osimertinib

Wayshine Biopharm, Inc.

Phase 1/2

Shanghai

2025-10-17

Active, closed

A Study to Evaluate the Efficacy and Safety of Zanubrutinib in Chinese Adults With Treatment-Naive Waldenström Macroglobulinemia

NCT07169331Waldenström's Macroglobulinemia

DrugZanubrutinib

BeiGene

Phase 4

Beijing, Guangzhou, Baoding, Yichang, Changsha, Hangzhou

2025-10-17

Recruiting

Safety and Efficacy of NK510 to Treat Gastric Cancer and Colorectal Cancer

NCT07166263Gastric Cancer (GC), Colorectal Cancer

DrugNK510

Base Therapeutics (Shanghai) Co., Ltd.

Early Phase 1

Nanjing

2025-10-16

Recruiting

A Study of Brenipatide in Participants With Alcohol Use Disorder

NCT07219953Alcohol Use Disorder

DrugBrenipatide

Eli Lilly and Company

Phase 3

1,100

Beijing, Changsha, Cheng Du Shi, Chengdu, Guangzhou, Hangzhou, Harbin, Hefei

2025-10-16

Recruiting

Construction of a Portal Hypertension Biobank

NCT07419724Variceal Bleeding, Portal Hypertension

Shanghai Zhongshan Hospital

Observational

1,000

Shanghai

2025-10-16

Active, closed

Predictive Value of Exosomes in Pleural Effusion for Advanced Lung Cancer

NCT07262671NSCLC (Advanced Non-small Cell Lung Cancer)

Fudan University

Observational

100

Shanghai

2025-10-16

Recruiting

The Effect of Bifidobacterium Probiotics on Gut Microbiota Changes in Healthy Adults During Short-term Travel Along the Silk Road

NCT07182500Healthy Adult Volunteer

Universiti Sains Malaysia

Phase 2

Huangpu

2025-10-16

Recruiting

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

NCT07209761Rifampicin-Resistant Pulmonary Tuberculosis, Multidrug-Resistant Pulmonary Tuberculosis

DrugsPretomanid·Bedaquiline·Linezolid·Moxifloxacin

Otsuka Pharmaceutical Development & Commercialization, Inc.

Phase 3

532

Beijing, Fuzhou, Shenzhen, Wuhan, Nanjing, Jinan, Shanghai, Chengdu

2025-10-16

Recruiting

Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury

NCT07486804Non-suicidal Self-injury

Anhui Medical University

Not applicable

Hefei

2025-10-16

Recruiting

A Single-arm, Open-label Study of GK01 in Combination With or Without Chemotherapy for the Adjuvant Treatment of Solid Tumors

NCT07351903Solid Tumors

DrugGK01

Tianjin Medical University Cancer Institute and Hospital

Phase 1

Tianjin

2025-10-16

Recruiting

NeoCSR-Omics Trial: CAPOX + Serplulimab Before vs. After Short-course RT in LARC

NCT07898865Rectal Cancer Patients, Locally Advanced Rectal Cancer (LARC)

DrugsSerplulimab·Folfox

Chongqing University Cancer Hospital

Phase 2

100

Chongqing

2025-10-16

Recruiting

A Study of HRS-2329 in Participants With Advanced Solid Tumors Harboring RAS Mutations or Amplifications

NCT07189949Advanced Solid Tumors Harboring RAS Mutations or Amplifications

DrugHRS-2329

Jiangsu HengRui Medicine Co., Ltd.

Phase 1

120

Tianjin

2025-10-16

Recruiting

Study on the Safety and Efficacy of PA9159 Inhalation Aerosol for the Treatment of Adult Bronchial Asthma

NCT07324707Bronchial Asthma

DrugPA9159 Metered- , per day for 28 days

Anhui Palo Alto Pharmaceuticals, Inc.

Phase 2

Nanchang

2025-10-15

Recruiting

CS-121 APOC3 Base Editing in FCS

NCT07176923Familial Chylomicronemia Syndrome (FCS)

DrugCS-121

CorrectSequence Therapeutics Co., Ltd

Early Phase 1

Hefei

2025-10-15

Recruiting

The Impact of Probiotic Intervention on the Gut Microbiota and Bowel Function

NCT07369830Rectal Cancer

DrugClostridium butyricum (live)

Huashan Hospital

Not applicable

156

Shanghai

2025-10-15

Recruiting

Iparomlimab and Tuvonralimab Plus Hypofractionated Radiotherapy and Chemotherapy for HAHNSCC

NCT07447570Head and Neck Cancer, Radiotherapy, Anti-PD-1/CTLA-4 Antibody

DrugIparomlimab and Tuvonralimab

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

Hangzhou

2025-10-15

Recruiting

Aspirin Continuation or Discontinuation in Conservative Treatment for Chronic Subdural Hematoma

NCT07240454Chronic Subdural Hematoma

Tao Liu

Not applicable

143

Beijing, Tianjin

2025-10-15

Not yet open

Fruquintinib Combined With Standard Chemotherapy Versus Standard Chemotherapy as First-line Treatment for Advanced pMMR Endometrial Cancer

NCT07170982Endometrial Cancer

DrugFruquintinib

Sun Yat-sen University

Phase 2

128

Guangzhou

2025-10-15

Not yet open

Iparomlimab and Tuvonralimab Combined With GC in Advanced ICC

NCT07152769Advanced Intrahepatic Cholangiocarcinoma

DrugsIparomlimab and Tuvonralimab·Sintilimab

Fudan University

Phase 2

104

Shanghai

2025-10-15

Recruiting

The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors

NCT07159048Hepatocellular Carcinoma, Colorectal Cancer Liver Metastasis

Fudan University

Not applicable

120

Shanghai

2025-10-15

Recruiting

Pre-emptive Scalp Infiltration With Low-dose Flurbiprofen and Ropivacaine for Postoperative Analgesia After Craniotomy

NCT07209345Post-craniotomy, Pain

DrugRopivacaine

Beijing Tiantan Hospital

Not applicable

216

Beijing

2025-10-15

Recruiting

HD-tDCS for Adolescent Bipolar Depression Targeting S1

NCT07246044Adolescent, Bipolar Depression, tDCS, Primary Somatosensory Cortex

Jiangsu Province Nanjing Brain Hospital

Not applicable

100

Nanjing

2025-10-15

Recruiting

A Prospective, Single-Arm, Single-Center Phase II Study Evaluating the Efficacy and Safety of Chidamide Combined With PD-L1 Inhibitor, Carboplatin, and Etoposide as First-Line Treatment in Patients With Extensive-Stage Small-Cell Lung Cancer (ES-SCLC)

NCT07373964Small Cell Lung Cancer

China Medical University, China

Phase 2

Shenyang

2025-10-15

Recruiting

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

NCT07219966Alcohol Use Disorder

DrugBrenipatide

Eli Lilly and Company

Phase 3

1,100

Beijing, Changsha, Cheng Du Shi, Chengdu, Guangzhou, Hangzhou, Harbin, Huzhou

2025-10-15

Active, closed

Fertility Decision and Outcomes in Young Women With Breast Cancer

NCT07804745Breast Cancer - Female, Fertility

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

300

Changchun, Hangzhou

2025-10-15

Recruiting

Clinical Study of 177Lu-CTR-FAPI In the Treatment of Patients With Advanced, Metastatic Solid Tumors

NCT07229768Pancreatic Cancer

Yan Xing

Early Phase 1

Shanghai

2025-10-15

Recruiting

A Study to Assess Safety, Tolerability and Drug Levels of Navlimetostat (BMS-986504) in Participants With Advanced Solid Tumors

NCT07077434Advanced Solid Tumors

DrugNavlimetostat

Bristol-Myers Squibb

Phase 1

Beijing, Fuzhou, Guangzhou, Shenzhen, Harbin, Xinxiang, Jinan, Tianjin

2025-10-15

Not yet open

Personalized KXV01 TCR Lentinvivo Injection as the Therapy for Advanced Solid Tumors

NCT07207681Advanced Solid Tumors

DrugKXV01 TCR Lentinvivo

The First Hospital of Jilin University

Phase 1

Changchun

2025-10-15

Not yet open

A Study of IMM2510 + IMM01 Combination Therapy in Patients With Advanced Solid Tumors

NCT07170787Advanced Solid Tumors

DrugsIMM2510·Timdarpacept

ImmuneOnco Biopharmaceuticals (Shanghai) Inc.

Phase 1/2

104

Shanghai

2025-10-15

Recruiting

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

NCT07206056Progressive Metastatic Castrate Resistant Prostate Cancer

DrugLuxdegalutamide

Novartis Pharmaceuticals

Phase 1/2

188

Beijing

2025-10-15

Recruiting

Relative Bioavailability of First vs Second-Generation Formulations of HRS9531 Tablets in Obese or Overweight Subjects

NCT07150962Overweight or Obesity

Fujian Shengdi Pharmaceutical Co., Ltd.

Phase 1

168

Hefei

2025-10-15

Recruiting

Integrated Clinical Study of Traditional Chinese and Western Medicine for Refractory Rheumatoid Arthritis

NCT07721142Rheumatoid Arthritis (RA)

Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine

Phase 4

300

Shanghai

2025-10-15

Recruiting

A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors

NCT07160725Solid Tumours

DrugPumitamig

Bristol-Myers Squibb

Phase 1/2

540

Guangzhou

2025-10-15

Recruiting

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

NCT07165028Metabolic Dysfunction-Associated Steatotic Liver Disease

DrugsRetatrutide·Tirzepatide

Eli Lilly and Company

Phase 3

4,500

Beijing, Changsha, Chengdu, Chongqing, Foshan, Fuzhou, Guangzhou, Guiyang

2025-10-15

Active, closed

The Value of Novel Thrombus Markers in the Diagnosis and Treatment of Acute Pulmonary Embolism

NCT06907238Acute Pulmonary Embolism

Beijing Anzhen Hospital

Observational

400

Beijing

2025-10-14

Recruiting

SHR2554 Combined With Endocrine Therapy in Advanced Breast Cancer

NCT07125950Advanced Breast Cancer

DrugsHRS-8080·Zeprumetostat

Henan Cancer Hospital

Phase 2

Zhengzhou

2025-10-14

Recruiting

To Evaluate the Safety and Efficacy of RNK08954 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.

NCT07303465KRAS G12D Mutations, Pancreatic Ductal Adenocarcinoma (PDAC)

DrugRNK08954

Ranok Therapeutics (Hangzhou) Co., Ltd.

Phase 2

Nanjing, Shanghai

2025-10-14

Recruiting

A Study of LUCAR-DKS1 in Subjects With Relapsed/Refractory Autoimmune Diseases

NCT07095075Relapsed/Refractory Autoimmune Diseases

Nanjing Legend Biotech Co.

Early Phase 1

Bengbu, Hefei, Nanjing, Suzhou, Wenzhou

2025-10-14

Recruiting

Study in Human iPSCs-derived RPE Cells Transplantation for Advanced (Late-stage) AMD

NCT07418177AMD - Age-Related Macular Degeneration

DrugsErlotinib·Prednisone

The First Affiliated Hospital with Nanjing Medical University

Phase 1/2

Nanjing

2025-10-14

Recruiting

Ventricular Tachycardia：A Registry Study

NCT07149701Ventricular Tachycardia (VT), Structural Heart Disease

Beijing Anzhen Hospital

Observational

1,000

Beijing

2025-10-14

Recruiting

A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease

NCT07787182Healthy Volunteers, Alzheimer Disease, Amyloid, Plaque, Amyloid

DrugLY4405094

Eli Lilly and Company

Phase 1

Beijing, Minhang District, Shanghai

2025-10-14

Recruiting

Efficacy and Safety of QD202 in Participants With Acute Ischemic Stroke Undergoing Thrombolysis Excluding Endovascular Thrombectomy

NCT07581210Acute Ischemic Stroke

Shanghai QuietD Biotechnology Co., Ltd.

Phase 2

120

Meizhou, Luoyang, Nanyang, Changchun, Meihekou, Benxi, Fuxin, Shengyang

2025-10-14

Recruiting

HerResolve™ in Detecting the Presence of Endometriosis Among Symptomatic Women

NCT07006987Endometriosis

Chinese University of Hong Kong

Not applicable

100

Hong Kong

2025-10-14

Recruiting

Efficacy and Safety of HDM1005 in Chinese Obesity or Overweight Patients Without Diabetes

NCT07279194Obesity & Overweight

DrugsHDM1005 1·HDM1005 2

Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.

Phase 3

825

Shanghai

2025-10-14

Active, closed

A Study Evaluating BAT3306 Compared With Keytruda® in NSCLC Cancer Participants

NCT07180862Carcinoma, Non-Small-Cell Lung

DrugPembrolizumab

Bio-Thera Solutions

Phase 1

160

Wuhan

2025-10-14

Active, closed

SH-SDU Shandong Endometriosis Reproductive Cohort

NCT07558629Endometriosis, Omics, Assisted Reproductive Technology

The Second Hospital of Shandong University

Observational

5,000

Jinan

2025-10-14

Recruiting

Burst Stimulation for Paroxysmal Atrial Fibrillation

NCT07281898Paroxysmal Atrial Fibrillation

Zhibing Lu

Not applicable

240

Wuhan, Xiangyang, Yichang

2025-10-13

By invitation

A Phase I Study to Evaluate the Safety, Tolerability, and Immunogenicity of an mRNA Vaccine Against Herpes Simplex Virus Type 2 (HSV-2) Post-Vaccination

NCT07330440Genital Herpes

Changchun BCHT Biotechnology Co.

Phase 1

144

Beijing

2025-10-13

Active, closed

Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Barrier Repair

NCT07645339Impaired Barrier

L'Oreal

Not applicable

Shanghai

2025-10-13

Recruiting

A Study of Recombinant Von Willebrand Factor (rVWF) in Chinese Participants With Von Willebrand Disease (vWD)

NCT07129343Von Willebrand Disease (VWD)

DrugsAdvate·Vonicog Alfa

Takeda

Phase 3

Beijing, Guangzhou, Jihan, Shanghai, Suzhou, Tianjin, Wuhan

2025-10-13

Recruiting

Effectiveness of High-Energy Density Enteral Nutrition for Enhancing Physical Growth and Cognitive Brain Development in Infants With Congenital Heart Disease

NCT07115108Congenital Heart Disease, Enteral Nutrition, Pediatrics

Children's Hospital of Fudan University

Not applicable

160

Shanghai

2025-10-13

Recruiting

Exploratory Study of Personalized mRNA Vaccine in Patients With Refractory Rhabdomyosarcoma

NCT06932861Rhabdomyosarcoma

Xinxin Zhang

Early Phase 1

Beijing

2025-10-13

Recruiting

Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children

NCT06850220Pediatric Obstructive Sleep Apnea, Cognition, Empathy, EEG

Children's Hospital of Soochow University

Observational

150

Suzhou

2025-10-13

Recruiting

Indometacin With or Without Aggressive Intravenous Hydration to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy

NCT07202559Pancreatitis, Chronic, Pancreatitis, Acute, Pancreatic Duct Stones

Changhai Hospital

Not applicable

1,250

Baotou, Beijing, Hangzhou, Hunan, Lanzhou, Shandong, Shanghai, Yunnan

2025-10-13

Recruiting

Herombopag Treated T-DM1 Induced Platelet Reduction

NCT07257809Thrombocytopenia

DrugHerombopag olamine

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase 2

Guangzhou

2025-10-13

Recruiting

A Study of CEA-Targeted CAR-T Therapy in Patients With CEA-Positive Advanced Solid Tumors

NCT07250386NSCLC (Advanced Non-small Cell Lung Cancer), Breast Cancer

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 1

Hangzhou

2025-10-13

Recruiting

An in Vivo CT Imaging Study of GMA-Tulip, I-gel, and LMA Supreme (GLAM-II)

NCT07196696Supraglottic Airway Device

Zhejiang Cancer Hospital

Not applicable

Hangzhou

2025-10-12

Active, closed

Mucosal and Systemic Immune Responses Induced by an Intranasal Influenza Live Attenuated Vaccine

NCT07232745Influenza

DrugLAIV

Jiangsu Province Centers for Disease Control and Prevention

Phase 4

Lianyungang

2025-10-12

Recruiting

Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery

NCT07192029Stroke

Xuanwu Hospital, Beijing

Not applicable

364

Fuzhou, Zhangzhou, Beijing

2025-10-12

Recruiting

Study on the Effects of Probiotic on Infant Gut Microbiota and Immune Regulation

NCT07896083Healthy Infants

BYHEALTH Co., LTD

Not applicable

370

Dalian

2025-10-11

Recruiting

Brain Cognitive Network Abnormalities in Anemia Patients Using fNIRS

NCT07578675Aplastic Anemia, Myelodysplastic Syndromes, Autoimmune Hemolytic Anemia, Functional Near-Infrared Spectroscopy

Institute of Hematology & Blood Diseases Hospital, China

Observational

323

Tianjin

2025-10-11

Active, closed

Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Aging

NCT07780799Aging, Dry Skin

L'Oreal

Not applicable

Shanghai

2025-10-11

Recruiting

A Trial to Evaluate the Efficacy, Safety, PK, and PD of HP515 in Non - Alcoholic Fatty Liver Disease ( NASH/MASH )

NCT07308548NAFLD (Non-alcoholic Fatty Liver Disease)

Hinova Pharmaceuticals Inc.

Phase 2

Beijing, Chengdu

2025-10-11

Recruiting

Non-pharmacological Auditory and Somatosensory Stimulation in Anesthetic Emergence

NCT07339618General Anesthetic, Electroencephalographic

West China Hospital

Not applicable

205

Chengdu

2025-10-11

Recruiting

A Phase II Trial of SHR-A1811 in HER2-Expressing Recurrent/Metastatic Cervical Cancer

NCT07051486Recurrent or Metastatic Cervical Cancer

DrugTrastuzumab Rezetecan

Jiangsu HengRui Medicine Co., Ltd.

Phase 2

Fuzhou, Jinan

2025-10-11

Recruiting

Using ctDNA Methylation to Monitor Metastatic Colorectal Cancer Treatment (PROMET)

NCT07283575Metastatic Colorectal Cancer ctDNA Surveillance

Fudan University

Observational

497

Shanghai

2025-10-10

Recruiting

Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABG

NCT07883499Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease

Xin Lou

Observational

150

Beijing

2025-10-10

Recruiting

Prospective Clinical Trial of Crisugabalin Capsules in the Treatment of Generalized Anxiety Disorder

NCT07330648Generalized Anxiety Disorder

DrugsCrisugabalin·Venlafaxine

Anhui Medical University

Phase 2

216

Hefei

2025-10-10

Recruiting

The Fever Clinic Acute Respiratory Cohort

NCT07278700Acute Respiratory Infections, Febrile Illnesses, Community-acquired Pneumonia, Viral Respiratory Tract Infections

Fudan University

Observational

1,000

Shanghai

2025-10-10

Recruiting

A Phase 1 Study of ADI-001 in Rheumatoid Arthritis

NCT07100873Rheumatoid Arthritis (RA)

DrugsADI-001·Fludarabine·Cyclophosphamide

Adicet Therapeutics

Phase 1

Shanghai

2025-10-10

Not yet open

A Study of CAR-T Cells in Subjects With Systemic Lupus Erythematosus

NCT06900764Systemic Lupus Erythematosus (SLE)

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Not applicable

Wuhan

2025-10-10

Recruiting

Tislelizumab Combined With Chemotherapy Followed by Thoracic Consolidation Radiotherapy in the First-line Treatment of Extensive Stage Small Cell Lung Cancer

NCT07425795Extensive Stage Small Cell Lung Cancer (ES-SCLC)

DrugTislelizumab

Chongqing University Cancer Hospital

Phase 2

Chongqing

2025-10-10

Not yet open

Combination Therapy of Senaparib and Bevacizumab for First-line Maintenance Therapy in Newly Diagnosed Advanced Homologous Recombination Proficient Ovarian Cancer Based on Exosome Protein Marker

NCT07120451Advanced Ovarian Cancer

DrugsSenaparib·Bevacizumab

Fudan University

Phase 2

Shanghai

2025-10-10

Not yet open

Exploring Gut Microbiome Differences in Female Cancer Patients With Varied Ovarian Function and Fertility Outcomes Following Immune Checkpoint Inhibitor Therapy

NCT07201259Malignant Tumors

West China Second University Hospital

Observational

Chengdu

2025-10-10

Active, closed

Biomechanical Simulation Analysis of the Lower Extremity During Running in Males With Type A Lower Crossed Syndrome.

NCT07397143Lower Crossed Syndrome

Universiti Sains Malaysia

Not applicable

Shijiazhuang

2025-10-10

Not yet open

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial on the Treatment of Hypertensive Intracerebral Hemorrhage With Naoxuekang Dropping Pills

NCT07200921Hypertensive Intracerebral Hemorrhage, Cerebral Small Vessel Diseases

Beijing Tiantan Hospital

Phase 2

1,950

Beijing

2025-10-10

Recruiting

Induction High-Low Dose Radiotherapy Plus Anti-PD-1 Followed by Definitive Radiotherapy in Recurrent Nasopharyngeal Carcinoma (Single-Arm Phase II)

NCT07277764Nasopharyngeal Carcinoma (NPC), Recurrent Nasopharyngeal Neoplasms

Jiangxi Provincial Cancer Hospital

Phase 2

Nanchang

2025-10-10

Recruiting

The Effectiveness of Guided Written Exposure Therapy for Complex PTSD in Adolescents

NCT07325734CPTSD, Compelx Post-traumatic Stress Disorder

Peking University

Not applicable

130

Fuyang, Beijing, Ulanhot, Ürümqi

2025-10-10

Not yet open

A Study to Evaluate the Safety of GR2301 Injection in Healthy Volunteers.

NCT07190716Single Ascending Dose, Healthy Subjects

DrugGR2301

Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Phase 1

Beijing

2025-10-10

Not yet open

The Treatment of Unresectable Liver Cancer With E-TACE Combined With Donafenib：A Prospective, Single-arm, Multicenter, Observational Study

NCT07180459Carcinoma, Hepatocellular Carcinoma

DrugDonafenib

Xuhua Duan

Observational

118

Guiyang, Haikou, Kaifeng, Luohe, Luoyang, Nanyang, Shangqiu, Zhoukou

2025-10-10

Recruiting

Reconstruction Kinetics of γδ T Cells After Unrelated Cord Blood Transplantation

NCT07782684Hematologic Disease and Disorders

Anhui Provincial Hospital

Observational

100

Hefei

2025-10-09

Recruiting

Efficacy and Safety of Cold Atmospheric Plasma Combined With Endovascular Intervention for Diabetic Foot Ulcers With Lower Extremity Arterial Occlusion

NCT07198061Diabetic Foot Ulcers (DFU), Lower Extremity Arterial Occlusion

Shenyang Medical College

Not applicable

Anshan

2025-10-09

Recruiting

Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC

NCT07040072HNSCC

Beijing Tongren Hospital

Phase 1

Beijing

2025-10-09

By invitation

BMI Stratified Management Based on Meridian-Lymph Axis Theory for Lower Extremity Lymphedema After Gynecologic Cancer Surgery

NCT07374835Lower Extremity Lymphedema After Gynecologic Cancer Surgery

Hong Zhang

Not applicable

Wuhan

2025-10-09

Recruiting

An Empirical Study on the Mechanisms of Biopsychosocial Functional Improvement in Patients With Major Depressive Disorder Through Nature-Based Tourism Activities

NCT07180342Major Depressive Disorder

Shandong Provincial Hospital

Not applicable

Jinan

2025-10-09

Recruiting

A Clinical Study to Evaluate the Safety, Tolerability and Efficacy of BBM-A101 in the Treatment of Knee Osteoarthritis.

NCT07198555Knee Osteoarthritis

Belief BioMed (Beijing) Co., Ltd

Phase 1

Shenzhen, Shanghai

2025-10-09

By invitation

Stepwise Strategy for Treatment of Atrial Fibrillation Substrate Extended Study

NCT07380620Atrial Fibrillation

Yuehui Yin

Observational

5,000

Chongqing

2025-10-09

Recruiting

Node-Sparing Short-Course Radiation Combined With Capecitabine and PD-1/CTLA-4 for MSS Early Rectal Cancer

NCT07068763Rectal Cancer

DrugCapecitabine

Sir Run Run Shaw Hospital

Phase 2

Hangzhou

2025-10-09

Active, closed

Wearable NH₃ Sensor for Remote Non-invasive Monitoring and Diagnosis of Diabetic Kidney Disease

NCT07875010Diabetic Nephropathies MeSH:D003928, Diabetes Mellitus, Type 2, Kidney Diseases

Shanghai Pudong Hospital

Observational

380

Shanghai

2025-10-09

Recruiting

The Effects of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Anxiety Responses and Emotional Regulation

NCT07369908Healthy Male and Female Volunteers

University of Electronic Science and Technology of China

Not applicable

140

Chengdu

2025-10-09

Recruiting

Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients

NCT07116811Vestibular Schwannoma, Facial Nerve Paralysis

Beijing Tiantan Hospital

Phase 3

364

Beijing

2025-10-09

Recruiting

OPtimizing REperfusion by Primary Intra-Arterial ThRomboLysis for Medium Vessel Occlusion

NCT07137832Acute Ischemic Stroke

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase 3

530

Guangzhou

2025-10-09

Recruiting

Phase II Clinical Study of SHR2554 Tablets Combined With Other Anti-tumor Treatments in Non-small Cell Lung Cancer Subjects

NCT07175220Locally Advanced or Metastatic Non-small Cell Lung Cancer

DrugsSHR-A2102·Zeprumetostat·Retlirafusp alfa

Jiangsu HengRui Medicine Co., Ltd.

Phase 2

200

Guangzhou

2025-10-09

Recruiting

Sigh Ventilation in Cardiac Surgery

NCT07024420Postoperative Pulmonary Complications (PPCs), Cardiac Surgery in Adult Patient

Zhongda Hospital

Not applicable

686

Nanjing

2025-10-09

Not yet open

Evaluating Metabolic Health in People Aged 18 to 60 by Nutrilite Metabolic Health Index

NCT07161557Metabolic Abnormality, Metabolic Disorders

Amway (China) R&D Center

Observational

200

Shanghai

2025-10-09

Recruiting

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

NCT07140913Mania, Bipolar Disorder

DrugKarXT

Bristol-Myers Squibb

Phase 3

424

Beijing, Guangzhou, Baoding, Shijiazhuang, Changsha, Nanjing, Xi'an, Chengdu

2025-10-08

Active, closed

A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)

NCT07176390Arthritis, Rheumatoid

DrugsTulisokibart·Methotrexate

Merck Sharp & Dohme LLC

Phase 2

185

Beijing, Xiamen, Guangzhou, Xinxiang, Pingxiang, Linfen, Ürümqi, Linhai

2025-10-08

Recruiting

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

NCT07190248Non-small Cell Lung Cancer

Drugs) Berahyaluronidase alfa·Calderasib·Paraplatin·Pemetrexed

Merck Sharp & Dohme LLC

Phase 3

675

Hefei, Beijing, Fujian, Fuzhou, Guangzhou, Nanning, Jiamusi, Zhengzhou

2025-10-08

Recruiting

Prophylactic Dexamethasone Before Infliximab in Moderate-to-Severe IBD

NCT07385131Inflammatory Bowel Disease (IBD), CD - Crohn's Disease, UC - Ulcerative Colitis

DrugDexamethasone

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

300

Hangzhou

2025-10-08

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site. Derived from ClinicalTrials.gov. Retrieved 8 November 2026. https://priyalifescience.com/clinical-trials-china?page=13

Query this register directly

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,187 studies in total at the last sync on 07 Nov 2026, 03:17 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in China?

11,790 of the 19,187 studies in this register are recruiting new participants as of the 07 Nov 2026, 03:17 UTC sync. A further 3,998 have not yet opened recruitment, 2,715 are active but closed to new participants, and 684 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (423) Advanced Solid Tumors (187) Colorectal Cancer (179) Gastric Cancer (175) Hepatocellular Carcinoma (154) Advanced Solid Tumor (153) Non-Small Cell Lung Cancer (145) Solid Tumor (142) Acute Ischemic Stroke (140) Lung Cancer (135) Non-small Cell Lung Cancer (132) Pancreatic Cancer (131) Multiple Myeloma (128) Coronary Artery Disease (122) Prostate Cancer (110)

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Browse trials by site location

Beijing (5576) Shanghai (3879) Guangzhou (3345) Hangzhou (1819) Wuhan (1343) Chengdu (1307) Nanjing (1211) Changsha (1154) Chongqing (1078) Fuzhou (1040) Tianjin (934) Zhengzhou (931) Hefei (896) Jinan (783) Changchun (639)

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.