Clinical trial register · China

Clinical Trials in China

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 19187 matching records held by the registry are in this view. Synced 07 Nov 2026, 03:17 UTC

19187

Studies in scope

all four open statuses

11790

Recruiting now

open to new participants

2028

Lead sponsors

across recruiting studies

Top sites

Beijing 5576 Shanghai 3879 Guangzhou 3345 Hangzhou 1819 Wuhan 1343

Trials in this register

Status

Study

Lead sponsor

Phase

Enrol

Chinese sites

Start

Recruiting

A Study on Combined Low-pass Whole-genome and Methylome Testing of Bloody Nipple Discharge Specimens for Benign-Malignant Differentiation.

NCT07250204Breast Cancer, Nipple Discharge

Hubei Cancer Hospital

Observational

Wuhan

2025-12-21

Recruiting

Exploratory Study on mRNA Therapeutic Drug Targeting CD19 for the Treatment of Hematologic Malignancies

NCT07349849B-cell Malignancies

Xinqiao Hospital of Chongqing

Early Phase 1

Chongqing

2025-12-20

Recruiting

Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer

NCT07478731CRC (Colorectal Cancer)

Hong Qiu

Phase 2

Wuhan

2025-12-20

Not yet open

Spatiotemporal Single-cell Atlas of Peri-implant Soft Tissue Healing

NCT07279090Peri-implant Soft Tissue Healing

Stomatological Hospital Affiliated with Fujian Medical University

Not applicable

Fuzhou

2025-12-20

Recruiting

The Value of GRPR PET Imaging for Diagnosis and Staging in Prostate Cancer

NCT07363382Prostate Cancer (Adenocarcinoma)

First Affiliated Hospital of Fujian Medical University

Phase 1/2

Fuzhou

2025-12-20

Not yet open

Video Intervention to Reduce Depression-related Stigma Among Adolescents

NCT07282366Depression - Major Depressive Disorder

Jian-Jun Ou

Not applicable

500

Changsha

2025-12-20

Recruiting

Impact of Emotional Disorders on Response to Immune Checkpoint Inhibitor Therapy in Liver Cancer

NCT07325565Liver Cancer, Emotional Disorder

Tongji Hospital

Observational

651

Wuhan

2025-12-20

Recruiting

Obinutuzumab, Zanubrutinib, and Lenalidomide in First-line Treatment of Mantle Cell Lymphoma

NCT07261163Mantle Cell Lymphoma

DrugsZanubrutinib·Obinutuzumab·Lenalidomide

Institute of Hematology & Blood Diseases Hospital, China

Phase 2

Tianjin

2025-12-20

By invitation

Based on ctDNA-MRD Guided Adjuvant Treatment Escalation After Definitive Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Study on Safety and Efficacy

NCT07371247Esophageal Cancer, MRD, ctDNA

The First Affiliated Hospital with Nanjing Medical University

Early Phase 1

Nanjing

2025-12-20

Recruiting

DIEP Flap Breast Reconstruction: Perioperative Biomarkers and Outcomes

NCT07263347Breast Neoplasms, Ischemia-Reperfusion Injury, Postoperative Complications, Wound Healing

Hubei Cancer Hospital

Observational

Wuhan

2025-12-20

Recruiting

GenSci143 in Participants With Advanced Solid Tumors

NCT07252414Advanced Solid Tumors

Changchun GeneScience Pharmaceutical Co., Ltd.

Phase 1

180

Zhengzhou, Wuhan, Changsha, Nanjing, Jinan, Shanghai, Taiyuan, Hangzhou

2025-12-20

Recruiting

A Multicenter, RAndomlzed, coNtrolled, umBrella Trial fOr Minimally Invasive Neurosurgery With Al-assisted Robotic guidanCe for Hemorrhagic Stroke: Large Basal Ganglia Hemorrhage

NCT06484374Hematoma Brain, Large Basal Ganglia Hemorrhage

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Not applicable

198

Nanjing

2025-12-20

Not yet open

Study on the Correlation Between Metabolomics and Anxiety and Depression in Bronchiectasis

NCT07291167Bronchiectasis

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

300

Wuhan

2025-12-20

Not yet open

SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer

NCT07297030Rectal Cancer

DrugFolfox

Sun Yat-sen University

Phase 2

Guangzhou

2025-12-20

Not yet open

Universal CAR-T Cell Injection Targeting CD19/BCMA in Patients With Inflammatory Bowel Disease

NCT07309744Moderate-to-severe Ulcerative Colitis, Crohn's Disease (CD)

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Early Phase 1

Wuhan

2025-12-20

By invitation

To Explore the Value of Magnetic Resonance Imaging in Noninvasive Quantitative Evaluation of Graft Function After Simultaneous Pancreas-kidney Transplantation

NCT07001917Simultaneous Pancreas-Kidney Transplantation

Zhen Li

Observational

500

Wuhan

2025-12-20

Recruiting

Research on a Machine Learning-Based Predictive Model for Difficult Intubation Using Specific Vocal Characteristics

NCT07278232Difficult Airway Intubation

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Observational

300

Shanghai

2025-12-20

Recruiting

Bioresorbable Sirolimus-eluting scaﬀold in de Novo Coronary Artery Lesions

NCT07022587De Novo Stenosis, Coronary Artery Disease

Xijing Hospital

Not applicable

2,000

Xi'an

2025-12-20

Active, closed

Immunogenicity and Safety of Sequential 2vHPV-9vHPV Vaccination in Girls Aged 9-14 Years

NCT07281677HPV Infection

Drugs9-valent HPV vaccine·Bivalent HPV vaccine

Zhejiang Provincial Center for Disease Control and Prevention

Phase 4

400

Lishui

2025-12-20

Active, closed

FANS-Assisted Mini-PCNL for Complex Renal Stones

NCT07332286Kidney Stones

The First Affiliated Hospital of Guangzhou Medical University

Not applicable

Guangzhou

2025-12-19

Recruiting

A Study to Evaluate the Efficacy and Safety of TTYP01 Tablets in Early Symptomatic Alzheimer's Disease

NCT07252440AD, Early Alzheimer's Disease

Shanghai Auzone Biological Technology Co., Ltd.

Phase 2

180

Chongqing

2025-12-19

Recruiting

Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine

NCT07203755Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis, Haemophilus Influenzae Type B Infection

DrugMCV4

CanSino Biologics Inc.

Phase 1

260

Shangqiu

2025-12-19

Recruiting

Allogeneic Anti-CD19/BCMA CAR-T for Refractory Graves' Disease

NCT07261345Graves' Disease

Shanghai Zhongshan Hospital

Early Phase 1

Shanghai

2025-12-19

Recruiting

Perioperative Cadonilimab Combined With Neoadjuvant Chemotherapy in Resectable Esophageal Squamous Cell Carcinoma (ESCC)

NCT07263919Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma

DrugsCadonilimab·Paclitaxel·Cisplatin

Akeso

Phase 2

Xi'an

2025-12-19

Recruiting

A Clinical Study Using FAPI-PET Imaging to Assess the Postoperative Effects of TAVI in Patients With Aortic Stenosis

NCT07335900Severe Aortic Valve Stenosis

RenJi Hospital

Not applicable

Shanghai

2025-12-19

Recruiting

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT07225946Prostatic Neoplasms, Castration-Resistant

DrugsPasritamig·Prednisone/Prednisolone·Docetaxel

Janssen Research & Development, LLC

Phase 3

800

Beijing, Chengdu, Chongqing, Guangzhou, Hangzhou, Nanjing, Shanghai, Tianjin

2025-12-19

Recruiting

KXV01 Injection in Patients With Advanced Solid Tumor (Including Osteosarcoma and Sarcoma)

NCT07596693Advanced Solid Tumors

DrugKXV01 TCR Lentinvivo

TCRx Therapeutics Co.Ltd

Phase 1

Shanghai

2025-12-19

Not yet open

A Multicenter Randomized Controlled Trial of Echocardiography-Guided Atrial Septal Defect Closure Performed in a Mobile Surgical Unit

NCT07273227ASD - Atrial Septal Defect

China National Center for Cardiovascular Diseases

Phase 4

300

Beijing

2025-12-19

Not yet open

Comparing the Therapeutic Efficacy of Extended Isthmusectomy Versus Total Thyroidectomy for Isthmus Tumors of the Thyroid

NCT07274605Thymectomy, Thyroid Cancer

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

520

Hangzhou

2025-12-19

Recruiting

KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

NCT07252739Malignant Neoplasm

DrugsCalderasib·Sacituzumab tirumotecan·Cetuximab·Keytruda

Merck Sharp & Dohme LLC

Phase 2

140

Nanjing, Nanchang, Shanghai, Chengdu

2025-12-19

Recruiting

Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies

NCT07309770Urachal Cancer, Advanced Solid Tumor Cancer, Antibody-drug Conjugates

DrugTrastuzumab Rezetecan

Sheng Zhang

Phase 2

Shanghai

2025-12-18

Active, closed

Twelve-lead Wearable Holter,MRI,CT,X-ray,Echocardiography

NCT07714109Cardiac Arrhythmia

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

500

Hangzhou

2025-12-18

Not yet open

Prospective Geometric Analysis of Ultra-Widefield OCTA Characteristics in Central Serous Chorioretinopathy Patients

NCT07347119Central Serous Chorioretinopathy (CSC)

Sun Yat-sen University

Observational

120

Guangzhou

2025-12-18

Active, closed

Efficacy and Safety of Home-based Structured Physical Exercise in Patients With Acute Ischemic Stroke

NCT07271082Acute Ischemic Stroke

Capital Medical University

Not applicable

208

Fuyang, Suzhou, Beijing, Zhoukou, Shihezi

2025-12-18

Recruiting

A Cohort Study on the Association Between the ANS Function and Acute GvHD

NCT07374874Transplant-Related Disorder

Institute of Hematology & Blood Diseases Hospital, China

Observational

Tianjin

2025-12-18

Recruiting

TC-G203 for Patients With GPC3-Positive Advanced Solid Tumors

NCT07242417Solid Cancer, GPC3 Positive Hepatocellular Carcinoma

DrugsFludarabine·Cyclophosphamide

Beijing GoBroad Hospital

Early Phase 1

Beijing

2025-12-18

Recruiting

An Exploratory Clinical Study Evaluating the Safety and Efficacy of Allogeneic CAR-NK Cell Therapy for Metastatic Castration-resistant Prostate Cancer (mCRPC)

NCT07298239Prostate Cancer Castration-resistant Prostate Cancer

DrugAnti-PSMA CAR-NK

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Early Phase 1

Beijing

2025-12-18

Recruiting

A Study of Picankibart in Patients With Active Psoriatic Arthritis

NCT07295509Psoriatic Arthritis

DrugPicankibart

Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.

Phase 2/3

222

Hangzhou

2025-12-18

Active, closed

The Role of Trop2 in Radioactive Iodine-131 Therapy Sensitivity in Papillary Thyroid Carcinoma

NCT07314255PTC, I-131, Trop2

Jiangxi Provincial Cancer Hospital

Observational

Nanchang

2025-12-18

By invitation

Safety and Efficacy of Intravenous IDOV-Immune in Patients With Advanced Solid Tumors

NCT07656090Cancer

DrugIDOV-Immune

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Early Phase 1

Beijing

2025-12-18

Not yet open

Stereotactic Body Radiotherapy With Sequential Iparomlimab and Tuvonralimab (QL1706) + Chemotherapy as Neoadjuvant Therapy in Patients With Resectable Non-small-cell Lung Cancer in China (LUNG-Nanjing01): a Single-arm, Single-centre, Phase 2 Trial

NCT07286942NSCLC, NSCLC (Non-small Cell Lung Cancer)

DrugLenvatinib

Jiangsu Cancer Institute & Hospital

Phase 2

Nanjing

2025-12-18

Recruiting

Safety and Pharmacokinetics of NM6603 in Chinese Patients With Advanced Solid Tumors

NCT07292038Cancers

NucMito Pharmaceuticals Co. Ltd.

Phase 1

Xiamen, Guangzhou, Zhengzhou

2025-12-18

Recruiting

A Clinical Trial Evaluating TQF3250 Capsules in Healthy Adult Subjects

NCT07327281Hyperglycemia

DrugTQF3250

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 1

Nanjing

2025-12-18

Recruiting

Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2

NCT07263308Acute Ischemic Stroke

DrugAlbumin

Capital Medical University

Phase 3

1,192

Anqing, Bozhou, Fuyang, Ma’anshan, Suzhou, Wuhu, Beijing, Fuzhou

2025-12-18

Recruiting

A Phase II Study of CM326 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease

NCT07418736Chronic Obstructive Pulmonary Disease

CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Phase 2

318

Beijing

2025-12-18

Recruiting

PET Myocardial Fatty-acid Metabolic Imaging With XTR003 Injection and 18F-FDG to Assess Myocardial Viability in Ischemic Cardiomyopathy

NCT07443696Ischemic Cardiomyopathy, Heart Failure

Sinotau Pharmaceutical Group

Phase 2

Beijing, Tianjin

2025-12-18

Recruiting

Phase II Study of EMB-01 in Recurrent/Metastatic Colorectal Cancer Patients

NCT07314294Metastatic Colorectal Cancer

Shanghai EpimAb Biotherapeutics Co., Ltd.

Phase 2

Beijing, Guangzhou

2025-12-18

Recruiting

Differences in N-CAD Concentration and Brain Function Between Children With ASD and TD

NCT07400484ASD

Chen Li

Observational

Chongqing

2025-12-18

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of GT729 Universal Cell Injection in the Treatment of Refractory or Relapsed Chronic Graft-versus-host Disease (cGVHD)

NCT07253259cGVHD

Grit Biotechnology

Early Phase 1

Tianjin

2025-12-18

Recruiting

A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B

NCT07285460Hemophilia

DrugsAntithrombin·Clotting factor concentrates·Fitusiran

Sanofi

Phase 3

Beijing, Wuhan

2025-12-18

Recruiting

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

NCT07185997Non-Small-Cell Lung Cancer, Metastatic Non-Small-Cell Lung Cancer, Advanced Non-Small-Cell Lung Cancer, EGFR P-Loop and Alpha C-Helix Compressing

DrugFurmonertinib

ArriVent BioPharma, Inc.

Phase 3

480

Hefei, Beijing, Chongqing, Fuzhou, Xiamen, Foshan, Guangzhou, Shantou

2025-12-17

Recruiting

The Safety and Efficacy of Daratumumab in Patients With Refractory Aplastic Anemia

NCT07287228Aplastic Anemia, Refractory, Relapse

DrugDaratumumab

Institute of Hematology & Blood Diseases Hospital, China

Phase 1/2

Tianjin

2025-12-17

By invitation

Safety, Tolerability, and Preliminary Efficacy of Hepatocyte-like Cell Injection for the Prevention and Treatment of Small-for-Size Syndrome

NCT07276568Small-for-size Syndrome

Zhi-Jun Zhu

Early Phase 1

Beijing

2025-12-17

Recruiting

Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases

NCT07464132Tumor, Cardiovascular Diseases, Pulmonary Fibrosis, Rheumatic Immune Diseases Involving Large Blood Vessels

Drug68Ga-NI-FAPI

Peking Union Medical College Hospital

Phase 1/2

Beijing

2025-12-17

Not yet open

Circulating Immune Markers for Prognostic Evaluation in Postoperative Lung Cancer Patients

NCT07242482Lung Cancer (Diagnosis), Biomarkers / Blood

Zhao Jun

Observational

200

Suzhou

2025-12-17

Recruiting

Irreversible Electroporation for Recurrent or Metastatic Cervical Lymph Node Metastases From Thyroid Cancer: A Prospective Multicenter Single-Arm Study

NCT07328243Thyroid Cancer Patients, Lymph Node Metastasis

Tian'an Jiang

Not applicable

Guangzhou, Hangzhou

2025-12-17

Active, closed

Ipromlimab and Tuvonralimab Combined With Albumin-Bound Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

NCT07374003Locally Advanced, Resectable

Sun Yat-sen University

Phase 2

Guangdong

2025-12-17

Recruiting

Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma and Urinary Tract Tumors

NCT07280832Unresectable Locally Advanced or Metastatic Melanoma, Unresectable Locally Advanced or Metastatic Urinary Tract Tumors

DrugJMT108

Shanghai JMT-Bio Inc.

Phase 1/2

500

Beijing

2025-12-17

Recruiting

Comparison of Etamsylate Versus Placebo to Prevent Bleeding in HSCT

NCT07442513Hematopoietic Stem Cell Transplantation, Thrombocytopenia

First Affiliated Hospital of Zhejiang University

Phase 3

404

Hangzhou

2025-12-16

Recruiting

Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid

NCT07311772Nasopharyngeal Cancinoma (NPC), Radiation-induced Oral Mucositis

Sun Yat-sen University

Phase 3

386

Beijing, Fuzhou, Guangzhou, Shantou, Zhuhai, Nanning, Wuzhou, Changsha

2025-12-16

Recruiting

A Clinical Trial of Influenza Virus Split Vaccine for Individuals Aged 60 Years and Above

NCT07302256Influenza

DrugInfluenza virus split vaccine

Shanghai Institute Of Biological Products

Phase 1

120

Wuhan

2025-12-16

Recruiting

Phase II Trial of Neoadjuvant Thymalfasin, PD-1 Inhibitor, and Chemoradiotherapy for cStage III GEJ Adenocarcinoma

NCT07277439Gastric Cancer

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2025-12-16

Not yet open

CT-Based Deep Learning for Differentiating Acute and Chronic Osteoporotic Vertebral Compression Fractures

NCT07306858Osteoporotic Vertebral Compression Fractures

Xin Fan

Observational

276

Chongqing

2025-12-16

By invitation

Handheld MPI Imaging to Track Stem Cells in Osteoarthritis

NCT07313020Knee Arthritis Osteoarthritis

Soochow University

Early Phase 1

Haikou

2025-12-16

Recruiting

A Phase II Trial of LM103 in Advanced Melanoma

NCT07310784Advanced Melanoma

DrugLM103 TILs

Suzhou BlueHorse Therapeutics Co., Ltd.

Phase 2

Beijing, Fuzhou, Guangzhou, Nanning, Zhengzhou, Wuhan, Nanjing, Changchun

2025-12-16

Recruiting

Clinical Trial of TQB2922 Injection (Subcutaneous Injection) in Patients With Advanced Cancers

NCT07260708Advanced Cancers

Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.

Phase 1

Beijing, Guangzhou, Zhengzhou, Changsha, Nanjing, Nanchang, Dalian, Jinan

2025-12-16

Recruiting

A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors

NCT07228247Solid Tumors, Adult

Hutchmed

Phase 1/2

147

Beijing, Changsha, Guangzhou, Hefei, Shanghai, Shenyang, Zhengzhou

2025-12-16

Recruiting

P-CABs-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication

NCT07285096Helicobacter Pylori Infection

Yueyue Li

Observational

1,730

Jinan

2025-12-16

Recruiting

Wearable Device-Based Early Warning of Postoperative Complications in Thoracic Surgery

NCT07646730Postoperative Complications, Thoracic Surgery, Perioperative Monitoring

Tongji Hospital

Observational

650

Wuhan

2025-12-16

Recruiting

DCSZ11 in Combination With Standard Therapy in Advanced or Metastatic Solid Tumors

NCT07035249DCSZ11, Solid Tumors, HNSCC

DrugDCSZ11

West China Hospital

Phase 1/2

Chengdu

2025-12-16

Recruiting

A Study to Assess the Safety and PK/PD of LBL-047 in Healthy Adults and Patients With Systemic Lupus Erythematosus

NCT07323173Systemic Lupus Erythematosus

Nanjing Leads Biolabs Co.,Ltd

Phase 1

117

Bengbu, Beijing, Guangzhou, Changsha, Nanjing, Pingxiang, Shanghai, Taiyuan

2025-12-16

By invitation

Observational Study on Dose Optimization of Olverembatinib in Patients With Chronic Myeloid Leukemia in Chronic or Accelerated Phase

NCT07383298Chronic Myeloid Leukemia

DrugOlverembatinib

Qian Jiang

Observational

100

Beijing

2025-12-16

Recruiting

Station 4L Lymph Node Dissection Versus No Dissection in Clinical Stage I Solid Nodule-Type Invasive NSCLC

NCT07801430Non-Small Cell Lung Cancer

Fudan University

Not applicable

384

Shanghai

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Flurbiprofen Patch in Patients With Herpes Zoster

NCT07370402Herpes Zoster, Pain

DrugFlurbiprofen

Beijing Tiantan Hospital

Not applicable

750

Beijing

2025-12-15

Active, closed

T Cell Receptor Gene-Engineered and Dominant Negative TGF-β Receptor T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

NCT07474168Tumor

Zhejiang University

Phase 1

Hangzhou

2025-12-15

Recruiting

Safety and Efficacy of Lactobacillus Plantarum for Psoriasis: A Randomized Double-Blind Placebo-Controlled Trial

NCT07194200Psoriasis, Lactobacillus Plantarum

Shenzhen People's Hospital

Phase 2

184

Shenzhen

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Baclofen in Patients With Herpes Zoster

NCT07378046Herpes Zoster, Pain

Beijing Tiantan Hospital

Not applicable

750

Beijing

2025-12-15

Recruiting

A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

NCT07276581Rheumatoid Arthritis

AstraZeneca

Phase 2

320

Beijing, Changchun, Changsha, Guangzhou, Jiujiang, Kunming, Linyi, Nanchong

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Crisugabalin in Patients With Herpes Zoster

NCT07307976Herpes Zoster, Pain

Beijing Tiantan Hospital

Not applicable

750

Beijing

2025-12-15

Not yet open

BEBT-908 Plus Chemotherapy Treatment for CR MRD-Positive MEF2D-Rearranged and Pre-B Acute Lymphoblastic Leukemia Patients

NCT07301138Acute Lymphoblastic Leukemia

DrugsIfupinostat Hydrochloride·Cytarabine·Methotrexate·Vincristine

Ruijin Hospital

Phase 2

Shanghai

2025-12-15

Recruiting

Low-Dose Radiotherapy and Anti-PD-1 Immunotherapy as Neoadjuvant Treatment for Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT07371234Locally Advanced Head and Neck Squamous Cell Carcinoma

DrugAdjuvant Cisplatin

Rui You

Phase 2

Guangdong

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Loxoprofen Sodium Patch in Patients With Herpes Zoster

NCT07378059Herpes Zoster, Pain

Beijing Tiantan Hospital

Not applicable

750

Beijing

2025-12-15

Not yet open

Host-Microbe Interactions in Biliary Dilatation

NCT07152496Choledochal Cyst

Beijing Tsinghua Chang Gung Hospital

Observational

400

Beijing

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Desvenlafaxine in Patients With Herpes Zoster

NCT07361809Herpes Zoster, Pain

Beijing Tiantan Hospital

Not applicable

750

Beijing

2025-12-15

Recruiting

A Phase Ia Study of KMY Tablets in Healthy Subjects

NCT07314541Healthy Volunteers

Lei Yunshang Group

Phase 1

120

Suzhou

2025-12-15

Recruiting

Lidocaine for LESS Postoperative Shoulder Pain Alleviation

NCT07537127Cystectomy, Myomectomy

Peking Union Medical College Hospital

Not applicable

100

Beijing

2025-12-15

Recruiting

Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

NCT07306286Pancreatic Adenocarcinoma Locally Advanced

Ruijin Hospital

Phase 2

Shanghai

2025-12-15

Not yet open

Multicenter Study on Early Arterial Changes in Prediabetic Patients Evaluated by Ultra-High-Frequency Ultrasound

NCT07271745Prediabetes

Chunyan Ma

Observational

1,740

Guangzhou, Nanning, Harbin, Jiamusi, Zhengzhou, Nanjing, Nanchang, Changchun

2025-12-15

Recruiting

IRE Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

NCT07306273Pancreatic Adenocarcinoma Locally Advanced

Ruijin Hospital

Phase 2

Shanghai

2025-12-15

Recruiting

Phase II Study of LM-24C5

NCT07387081Advanced Solid Tumor Cancer

DrugLM-24C5

LaNova Medicines Limited

Phase 2

130

Fuzhou, Shanghai

2025-12-15

Recruiting

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

NCT07282600Overweight, Obesity

DrugEloralintide

Eli Lilly and Company

Phase 3

1,035

Beijing, Chengdu, Chongqing, Guangzhou, Hefei, Jinan, Luoyang Shi, Nanchang

2025-12-15

Not yet open

A Prospective, Single-center, Randomized Controlled Clinical Study Evaluating the Efficacy and Safety of Hyperbaric Oxygen Therapy as an Adjunctive Treatment for Chronic Heart Failure

NCT07311109Chronic Heart Failure With Reduced Ejection Fraction

Fujian Medical University

Not applicable

150

Fuzhou

2025-12-15

Recruiting

The Effects of Low-Intensity Music in Adolescents With Anxiety

NCT07492472Anxiety

Jiangsu Province Nanjing Brain Hospital

Not applicable

Haikou

2025-12-15

By invitation

Extension Study of the PUMCH-E101 Clinical Trial：Safety and Efficacy Study of PUMCH-E101 Injection in the Contralateral Eye

NCT07878572Inherited Retinal Diseases

Peking Union Medical College Hospital

Early Phase 1

Beijing

2025-12-15

Recruiting

A ctDNA-guided Phase II Trial of Osimertinib in Combination With Sacituzumab Tirumotecan in EGFR-mutated Advanced NSCLC Patients With Positive ctDNA After lead-in Osimertinib Monotherapy

NCT07375316Non Small Cell Lung Cancer

DrugsSacituzumab tirumotecan·Osimertinib

Guangdong Association of Clinical Trials

Phase 2

120

Guangzhou, Meizhou, Shantou, Shenzhen

2025-12-15

Recruiting

Effectiveness of an Edge AI-based Augmented Reality System for Hand Hygiene Training: a Multi-centre, Mixed-methods Cluster Randomised Controlled Trial

NCT07280026Hand Hygiene Training, Infection Prevention and Control, Healthcare-Associated Infections (HAIs), Health Education

The Hong Kong Polytechnic University

Not applicable

1,000

Wuhan

2025-12-15

Recruiting

Superior HypogastrIc plExus bLock During Laparoscopic Colorectal Cancer Surgery

NCT07579780Colorectal Cancer (Diagnosis), Laparoscopic Surgery, Superior Hypogastric Plexus Block

Sixth Affiliated Hospital, Sun Yat-sen University

Not applicable

170

Guangzhou

2025-12-15

By invitation

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral F-02-2-Na Tablets in Adult Subjects

NCT07324434Hyperuricemia With or Without Gout

Guangdong Hengqin Novagains Biopharmaceutical Co., Ltd.

Phase 1

Guangzhou

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster

NCT07361796Herpes Zoster, Pain, Postherpetic Neuralgia

Beijing Tiantan Hospital

Not applicable

832

Beijing

2025-12-15

Not yet open

Evaluation of Neoadjuvant Therapy With Trastuzumab, Pertuzumab, Docetaxel, and QL1706 in Early or Locally Advanced HER2+ Breast Cancer

NCT07246317Breast Cancer

DrugsPertuzumab·Trastuzumab·Lenvatinib·Docetaxel

Tianjin Medical University Cancer Institute and Hospital

Phase 2

188

Guangzhou, Shijiazhuang, Luoyang, Nanyang, Chengdu, Tianjin, Jiaxing

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Mirogabalin in Patients With Herpes Zoster

NCT07307170Herpes Zoster, Mirogabalin, Pain

Beijing Tiantan Hospital

Not applicable

750

Beijing

2025-12-15

Recruiting

Non-Invasive Neuromodulation for Essential Tremor: Long-Term Safety and Effectiveness Study

NCT07774598Essential Tremor

Ruijin Hospital

Not applicable

Shanghai

2025-12-15

Not yet open

Site Preservation Was Performed Through an Open Healing Oral Restorative Membrane

NCT07334067Site Preservation, Soft Tissue Healing, Anterior Dental Aesthetic Area

The Dental Hospital of Zhejiang University School of Medicine

Not applicable

Hangzhou

2025-12-15

Recruiting

FIREFLY Trial: Fenofibrate Intervention---Randomized Evaluation in First-Line PBC Therapy

NCT07296458Primary Biliary Cholangitis (PBC)

DrugsFenofibrate·UDCA

Xijing Hospital of Digestive Diseases

Phase 3

132

Guangzhou, Xi'an

2025-12-15

Not yet open

CAR-T for Claudin18.2 Positive Solid Tumors

NCT07266311Claudin18.2 Positive Advanced Solid Tumors

Chengdu Ucello Biotechnology Co., Ltd.

Early Phase 1

Chengdu

2025-12-15

Recruiting

Humanistic Continuing Care Via WeChat for Patients Undergoing Thermal Ablation of Papillary Thyroid Carcinoma

NCT07302672Papillary Thyroid Carcinoma

Ming-an Yu

Not applicable

108

Beijing

2025-12-15

Recruiting

The Analgesic Efficacy and Safety of Tulodesvenlafaxine in Patients With Herpes Zoster

NCT07370389Herpes Zoster, Pain

Beijing Tiantan Hospital

Not applicable

750

Beijing

2025-12-15

Recruiting

Assessing Iparomlimab and Tuvonralimab in Recurrent or Metastatic MSI-H/dMMR Gastric Cancer

NCT07127822Gastric / Gastroesophageal Junction Adenocarcinoma, MSI-H Cancer

DrugIparomlimab and Tuvonralimab

Peking University

Phase 2

106

Shijiazhuang, Harbin, Zhengzhou, Nanjing, Xi'an, Qingdao, Taiyuan, Chengdu

2025-12-15

Not yet open

CLEAR Trial: CA330 Cytokine Adsorption Column for Anticoagulant/Antiplatelet Patients in Non-Elective CPB Surgery.

NCT07284199CABG, Aortic Dissection, Valvular Heart Diseases

Beijing Anzhen Hospital

Not applicable

120

Beijing

2025-12-15

Recruiting

A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus

NCT07444307Systemic Lupus Erythematosus (SLE)

Hangzhou Qihan Biotech Co., Ltd.

Phase 1

Hefei, Wuhan, Beijing

2025-12-15

Not yet open

Evaluating the Clinical Value of Transparent Cap-Assisted Second Examination of the Sigmoid Colon for Improving Colorectal Adenoma Detection Rates

NCT07261319Colorectal Adenoma

Fudan University

Not applicable

614

Shanghai

2025-12-15

Active, closed

the Exploration of MTAP Deletion in Osteosarcoma by Immunohistochemistry

NCT07593573Osteosarcoma, MTAP Deletion, Immunohistochemistry

Peking University People's Hospital

Observational

100

Beijing

2025-12-15

Active, closed

A Phase III Clinical Trial to Evaluate Long-Term Protective Efficacy of Recombinant Zoster Vaccine (CHO Cell)

NCT07293065Herpes Zoster

DrugRecombinant Zoster Vaccine

MAXVAX Biotechnology Limited Liability Company

Phase 3

12,000

Shijiazhuang, Zhengzhou, Wuhan, Kunming

2025-12-15

Recruiting

A Clinical Study on Minimal Residual Disease in Patients With Systemic Light Chain Amyloidosis

NCT07215494Light Chain (AL) Amyloidosis, MRD

Peking University First Hospital

Not applicable

Beijing

2025-12-15

Recruiting

Adjuvant Oxaliplatin Plus S-1 Versus Docetaxel Plus S-1 for Stage III Gastric Cancer

NCT07366528Gastric Cancer (GC), Adjuvant Chemotherapy, Stage 3 Cancer, Docetaxel

DrugsTeysuno·Docetaxel·Oxaliplatin

Ruijin Hospital

Phase 3

387

Shaoguan, Shanghai

2025-12-15

Not yet open

DPP4 Inhibitor Intervention on Post-stroke Cognitive Impairment in Ischemic Stroke Patients With Type 2 Diabetes

NCT07241897Ischemic Stroke, Diabete Mellitus

Second Affiliated Hospital of Soochow University

Phase 3

312

Suzhou

2025-12-15

Not yet open

PSMA-PET/MRI-Ultrasound Multimodal Fusion Navigation for Da Vinci Robot-Assisted Radical Prostatectomy: A Randomized Controlled Trial

NCT07272317Prostate Cancer

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Not applicable

Shanghai

2025-12-15

Recruiting

Proton vs Photon IMRT in Locally Advanced Nasopharyngeal Carcinoma: A Phase III Trial

NCT07340515Nasopharyngeal Carcinoma (NPC)

DrugsToripalimab·Cisplatin

Man Hu

Phase 3

300

Jinan

2025-12-15

Recruiting

Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China Population With Uncontrolled Type 2 Diabetes on Oral Agents

NCT07307235Type 2 Diabetes

DrugIGlarLixi

Shanghai Zhongshan Hospital

Phase 4

1,316

Hefei, Huizhou, Shenzhen, Harbin, Xinxiang, Wuhan, Changsha, Hengyang

2025-12-13

Recruiting

Correlation Between Perioperative EEG Variability and Postoperative Delirium Incidence.

NCT07323940Delirium - Postoperative

Xin Chen

Observational

Haikou

2025-12-12

Recruiting

A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

NCT07221474Squamous Non-small Cell Lung Cancer

DrugsIntismeran autogene·Nab-paclitaxel·Keytruda·Paclitaxel

Merck Sharp & Dohme LLC

Phase 2

180

2025-12-12

Recruiting

Non-invasive Ultrasound and Hematoma Clearance After Intracerebral Hemorrhage

NCT07246473Intracerebral Hemorrhage

Beijing Tiantan Hospital

Not applicable

Wuhu, Beijing

2025-12-12

Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

NCT07218380Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis

DrugsVepugratinib·Pembrolizumab

Eli Lilly and Company

Phase 3

450

Beijing, Changchun, Changsha, Chengdu, Chongqing, Guangzhou, Hangzhou, Harbin

2025-12-12

Not yet open

A Prospective, Phase II Clinical Study of HIPEC Combined With NIPS and Tislelizumab Conversion Therapy for Gastric Cancer With Peritoneal Metastasis With Positive Cytology Alone or PCI Score ≤10

NCT07304258Gastric Cancer Peritoneal Metastases

Hebei Medical University

Phase 2

Shijiazhuang

2025-12-12

Recruiting

Study Comparing ZG006 With Investigator-Selected Chemotherapy in Participants With Relapsed Small Cell Lung Cancer

NCT07189455Small-cell Lung Cancer

DrugsZG006·Topotecan

Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Phase 3

420

Shanghai

2025-12-12

Recruiting

Epidural Spinal Cord Stimulation for Restoring Walking in Spinal Cord Injury

NCT07306052Spinal Cord Injuries (SCI)

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

Hangzhou

2025-12-12

Recruiting

Clinical Study of UTAA07 Injection in the Treatment of Hematologic and Lymphatic Systemic Malignancies

NCT07338604Hematolymphoid Malignancies

PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Early Phase 1

Suzhou

2025-12-12

Active, closed

A Study to Evaluate the Safety and Tolerability of RAG-18 in Pediatric Patients With Duchenne Muscular Dystrophy

NCT07282652Duchenne Muscular Dystrophy (DMD)

Peking Union Medical College Hospital

Early Phase 1

Beijing

2025-12-12

Recruiting

SYS6010 Combined With Enlonstobart In Recurrent Or Metastatic Head And Neck Squamous Cell Carcinoma

NCT07254585Head and Neck Squamous Cell Carcinoma

DrugsEnlonstobart·SYS6010·Pembrolizumab

CSPC Megalith Biopharmaceutical Co.,Ltd.

Phase 2

110

Shanghai

2025-12-12

Recruiting

Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Gemcitabine Combined With Paclitaxel Protein-bound

NCT07716228Nausea and Vomiting Caused by Chemotherapy

DrugsAuricular point stimulation·Standard pharmacologic antiemetic·Dexamethasone

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 3

Hangzhou

2025-12-12

Recruiting

Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Trastuzumab Deruxtecan

NCT07716189Nausea and Vomiting Caused by Trastuzumab Deruxtecan

DrugsAuricular point stimulation·Standard pharmacologic antiemetic·Dexamethasone

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 3

Hangzhou

2025-12-12

Recruiting

AI System for Anatomic Recognition & Lesion Detection in Nasopharyngolaryngoscopy: A Prospective Study

NCT07326358Nasopharyngeal Neoplasms, Laryngeal Disease

Ruijin Hospital

Observational

500

Shanghai

2025-12-12

Recruiting

Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Docetaxel Plus Cyclophosphamide

NCT07716176Nausea and Vomiting Caused by Chemotherapy

DrugsAuricular point stimulation·Standard pharmacologic antiemetic·Dexamethasone

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 3

Hangzhou

2025-12-12

Recruiting

CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases

NCT07337785Relapsing or Refractory Multiple Sclerosis (MS), Myasthenia Gravis (MG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Autoimmune Encephalitis (AE)

Tongji Hospital

Early Phase 1

Wuhan

2025-12-12

Recruiting

KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer

NCT07481058Esophageal Squamous Cell Carcinoma (ESCC)

DrugsKC1036·Toripalimab·Paclitaxel·Cisplatin

Beijing Konruns Pharmaceutical Co., Ltd.

Phase 2

Beijing

2025-12-12

Active, closed

Cervical Cytology DNA Methylation for Endometrial Cancer Screening

NCT07874529Endometrial Cancer, DNA Methylation, Cytology, Cancer Screening

Lei Li

Observational

30,000

Beijing

2025-12-12

Active, closed

Efficacy and Safety of ZT006 in Overweight and Obese Participants

NCT07230132Overweight , Obesity

Beijing QL Biopharmaceutical Co.,Ltd

Phase 2

184

Handan, Langfang, Harbin, Luoyang, Chenzhou, Yueyang, Nanjing, Jinan

2025-12-12

Recruiting

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

NCT07222800Intestinal Neoplasms, Gastrointestinal Neoplasms, Digestive System Neoplasms, Neoplasms by Site

DrugsPF-08634404·Avastin·Bevacizumab

Pfizer

Phase 3

800

Hefei, Beijing, Chongqing, Fuzhou, Xiamen, Guangzhou, Meizhou, Nanning

2025-12-11

Recruiting

Efficacy and Safety of Recombinant Botulinum Toxin Type A (Eveotox) for Injection in the Treatment of Adult Upper Limb Spasticity .

NCT07242300Upper Limb Spasticity (ULS)

DrugRecombinant Botulinum Toxin Type A

JHM BioPharma (Tonghua) Co. , Ltd.

Phase 3

207

Bengbu, Hefei, Beijing, Chongqing, Guangzhou, Nanning, Cangzhou, Shijiazhuang

2025-12-11

Active, closed

A Study to Evaluate the PK Similarity of AK112 in Healthy Chinese Male Subjects

NCT07340476Healthy Male Subjects

DrugIvonescimab

Akeso

Phase 1

108

Zhejiang

2025-12-11

Active, closed

A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS)

NCT07223723Amyotrophic Lateral Sclerosis

DrugTofersen

Biogen

Phase 4

Beijing

2025-12-11

Recruiting

A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+

NCT07326215Acute Respiratory Distress Syndrome, Acute Kidney Injury

Vantive Health LLC

Not applicable

Beijing, Guangzhou, Shenzhen, Harbin, Nanjing, Nanchang, Shanghai, Chengdu

2025-12-11

Recruiting

AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population

NCT07277686Coronary Artery Disease (CAD), Artificial Intelligence Algorithms, Face, Screening

China National Center for Cardiovascular Diseases

Observational

1,392

Zhoukou, Beijing

2025-12-11

Not yet open

Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course Radiotherapy

NCT07302126Acute Radiation Enteritis

Sixth Affiliated Hospital, Sun Yat-sen University

Phase 2

Guangzhou

2025-12-11

Recruiting

Effect of Remote Ischemic Preconditioning on Early Neurological Deterioration in Acute Perforating Artery Infarction

NCT07237542Ischemic Stroke, Remote Ischaemic Preconditioning

Jinling Hospital, China

Not applicable

910

Nanjing

2025-12-11

Recruiting

Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases

NCT07301164System Lupus Erythematosus, Systemic Sclerosis (SSc), Inflammatory Myositis, Antiphospholipid Syndrome

Peking University Third Hospital

Early Phase 1

Beijing

2025-12-11

Recruiting

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

NCT07222267Breast Cancer, Advanced Solid Tumor

DrugBG-75202

BeOne Medicines

Phase 1

Beijing, Chongqing, Xiamen, Guangzhou, Harbin, Changsha, Nanjing, Shanghai

2025-12-11

Recruiting

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

NCT07226349Advanced Solid Tumor

DrugsBGB-43395·Fulvestrant

BeOne Medicines

Phase 1

105

Beijing, Guangzhou, Harbin, Wuhan, Nanjing, Jinan, Weifang

2025-12-11

Recruiting

Safety and Feasibility of IRE for Early-stage Breast Cancer: a Prospective, Open-Label, Single-Arm, Exploratory Study

NCT07263451Breast Cancer

Tian'an Jiang

Not applicable

Hangzhou

2025-12-11

Recruiting

A Real-World Study of Guselkumab in Chinese Participants With Ulcerative Colitis

NCT07302360Colitis, Ulcerative

Xian-Janssen Pharmaceutical Ltd.

Observational

200

Beijing, Changzhou, Guangzhou, Hangzhou, Nanjing, Shenzhen, Shijiazhuang, Tianjin

2025-12-11

Not yet open

CD19/BCMA CAR-T for SLE

NCT07266337SLE - Systemic Lupus Erythematosus

DrugAZD0120

Chengdu Ucello Biotechnology Co., Ltd.

Early Phase 1

Chengdu

2025-12-10

Recruiting

A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

NCT07232524Head and Neck Squamous Cell Carcinoma, Solid Tumor

DrugBL-M24D1

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Chengdu

2025-12-10

Recruiting

A Clinical Study to Evaluate LVIVO-TaVec200 for the Treatment of Relapsed/Refractory Multiple Myeloma

NCT07294625Multiple Myeloma

The First Affiliated Hospital with Nanjing Medical University

Early Phase 1

Zhengzhou, Nanjing, Xuzhou, Shanghai, Xi’an

2025-12-10

Recruiting

Alternating HAIC and Systemic Chemotherapy With or Without Adebrelimab and Apatinib for Unresectable Biliary Tract Cancer

NCT07569679Biliary Tract Cancer

DrugsApatinib·Adebrelimab·Gemcitabine·Cisplatin

Air Force Military Medical University, China

Phase 2

124

Xi'an

2025-12-10

Recruiting

Direct Visualization ERAT Versus Laparoscopic Appendectomy in Adults With Acute Uncomplicated Appendicitis

NCT07230379Acute Uncomplicated Appendicitis

Changhai Hospital

Not applicable

376

Chongqing, Guangzhou, Shenzhen, Kaifeng, Zhengzhou, Changsha, Suzhou, Nanchang

2025-12-10

Recruiting

Study Evaluating ISM5411 Administered Orally to Subjects With Active Ulcerative Colitis (BETHESDA)

NCT07265570Ulcerative Colitis

InSilico Medicine Hong Kong Limited

Phase 2

Beijing, Chongqing, Guangzhou, Huizhou, Nanning, Shijiazhuang, Luoyang, Xinxiang

2025-12-10

Recruiting

The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant Recipients

NCT07275632Delayed Graft Function, Kidney Transplantation

First Affiliated Hospital of Chongqing Medical University

Phase 1/2

Chongqing, Guangzhou

2025-12-10

Not yet open

Short-term Observation on the Clinical Application Effect of Astra Tech Implant EV Short Implants for Maxillary Sinus Elevation

NCT07271134Missing Teeth

Linhu Wang

Not applicable

Wuhan

2025-12-10

Not yet open

Female Autologous Platelet-Rich Plasma (PRP) Co-incubation With Husband's Sperm

NCT07282327Reproductive Issues

Chinese University of Hong Kong

Not applicable

288

Hong Kong

2025-12-10

Recruiting

Near-infrared Light Therapy Device for Mild-Moderate Alzheimer's Disease (NirsCure-03A)

NCT07262645Alzheimer s Disease

Danyang Huichuang Medical Equipment Co., Ltd.

Phase 3

320

Beijing, Shijiazhuang, Baotou, Suzhou, Xi'an, Shanghai, Taiyuan, Tianjin

2025-12-10

Not yet open

Osteomyelitis Multi-center Prospective Cohort Study

NCT07251374Osteomyelitis of Lower Extremities

Southwest Hospital, China

Observational

2,000

Chongqing

2025-12-10

Recruiting

Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis

NCT07289737Lumbar Degenerative Spondylolisthesis

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Observational

100

Yiwu

2025-12-10

By invitation

Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Ventilation

NCT07239557Major Abdominal Surgery, Atelectasis, Lung-protective Ventilation, Lung Ultrasound Score

Sixth Affiliated Hospital, Sun Yat-sen University

Not applicable

Guangzhou

2025-12-10

Recruiting

Effects of BLa80 and LRa05 on the Gut Microbiota Metabolite Profile of Healthy Individuals

NCT07287306Healthy Individuals

Wecare Probiotics Co., Ltd.

Not applicable

375

Guangzhou

2025-12-10

Not yet open

Songling Xuemaikang Capsules for Cerebral Small Vessel Disease

NCT07271732Hypertension, Cerebral Small Vessel Diseases

DrugSongling Xuemaikang

Dongzhimen Hospital, Beijing

Not applicable

Beijing

2025-12-10

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of GenSci140 in Participants With Advanced Solid Tumors

NCT07251166Advanced Solid Tumors

Changchun GeneScience Pharmaceutical Co., Ltd.

Phase 1

170

Shenyang

2025-12-10

Not yet open

Orlistat and Weight Management for Uric Acid Control in Obese Gout: A RCT

NCT07326839Gout, Obesity

DrugOrlistat

XueMei Guo

Not applicable

120

Shenyang

2025-12-10

Recruiting

A Study Evaluating the Vascular Healing and Neointimal Transformation at 1 Month After Implantation of BioFreedom™ Drug-coated Stents and the Xience Drug-eluting Stent System in Patients With Acute Coronary Syndrome and High Bleeding Risk Using Optical Coherence Tomography

NCT07230847Coronary Heart Disease, Acute Coronary Syndrome

China National Center for Cardiovascular Diseases

Not applicable

Beijing

2025-12-10

Recruiting

A Single-Center Phase 1 Study of ceAF for Knee Osteoarthritis (KOA)

NCT07902128Knee Arthritis, Osteoarthritis

Anhui HygeianCells BioMedical Co., Ltd.

Phase 1

Huangshan City

2025-12-10

Not yet open

Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric Retention

NCT07276763Gastric Retention

Fudan University

Observational

16,509

Shanghai

2025-12-10

Not yet open

The Percutaneous Interventional Surgery Control System for Pulmonary Nodule Biopsy

NCT07277088Pulmonary Nodules, Lung Cancer (Diagnosis), Percutaneous Needle Biopsy, Transthoracic Needle Biopsy

Jiayuan Sun

Not applicable

158

Shanghai

2025-12-10

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

NCT07155187Non-Small Cell Lung Cancer, c-MET

DrugsTelisotuzumab Adizutecan·Osimertinib

AbbVie

Phase 2/3

490

Guangzhou, Nanchang, Shanghai, Ürümqi

2025-12-10

Not yet open

A Study of ABSK061 to Assess Safety, Tolerability, Pharmacokinetics, and Efficacy in Children With Achondroplasia

NCT07297875Achondroplasia

DrugABSK061

Abbisko Therapeutics Co, Ltd

Phase 1/2

110

Beijing, Zhengzhou, Wuhan, Shanghai, Chengde, Chengdu, Hangzhou

2025-12-10

Recruiting

A Study of Lutetium [177Lu]-BL-ARC001 in Patients With Locally Advanced or Metastatic Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

NCT07274852Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma, Solid Tumors

DrugLutetium [177Lu] BL-ARC001

Sichuan Baili Pharmaceutical Co., Ltd.

Phase 1

Chengdu

2025-12-10

Recruiting

A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation

NCT07342205Acute Respiratory Distress Syndrome (ARDS), Acute Lung Injury(ALI), Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome

Shanghai University of Traditional Chinese Medicine

Phase 2/3

Shanghai

2025-12-10

Not yet open

Gait and Paraspinal sEMG in Degenerative Spinal Diseases

NCT07309926Adult Spinal Deformity, Degenerative Scoliosis, Sagittal Deformity, Sagittal Imbalance

Xuanwu Hospital, Beijing

Observational

120

Beijing

2025-12-10

Recruiting

Evaluation of the Effect of Using Ultrasound Robots for Breast Cancer Screening

NCT07331363Breast Cancer, Ultrasound

Huazhong University of Science and Technology

Not applicable

70,000

Xiantao

2025-12-10

Not yet open

Nimotuzumab Combined With Nab-paclitaxel/Gemcitabine in the Perioperative Treatment of High-risk Resectable/Borderline Resectable Pancreatic Cancer

NCT07277452Pancreatic Cancer, Adult

DrugNimotuzumab

The First Affiliated Hospital with Nanjing Medical University

Phase 2

156

Nanjing, Beijing

2025-12-10

Not yet open

The Effects of Neuromuscular Training on Knee Biomechanics During Jump-Landing Among College Basketball Players Post ACL Reconstruction and Rehabilitation

NCT07314931Anterior Cruciate Ligament Reconstruction Rehabilitation, Knee Injuries, Biomechanical Data, Athletic Performance

Universiti Sains Malaysia

Not applicable

Chengde

2025-12-10

Recruiting

Intermittent Fasting on the Blood Microbiome

NCT06678516Healthy

Erasmus Medical Center

Not applicable

Lanzhou

2025-12-10

Recruiting

Intermittent Theta Burst Stimulation of the Prefrontal Cortex in Social Anxiety Disorder

NCT07466277Social Anxiety Disorder (SAD)

Second Affiliated Hospital, Zhejiang University, School of Medicine

Not applicable

100

Hangzhou

2025-12-09

Recruiting

The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality

NCT07541924Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort

DONG WU

Not applicable

200

Beijing

2025-12-09

Recruiting

HC010 in First-line PD-L1 Positive Advanced NSCLC Patients

NCT07169552NSCLC

DrugHC010

HC Biopharma Inc.

Phase 2

Shanghai

2025-12-09

Recruiting

A Clinical Study Assessing the Subcutaneous Formulation of TQB2934 for Injection in Subjects With Malignant Plasma Cell Tumors

NCT07179679Multiple Myeloma

DrugTQB2934

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Phase 1

Chongqing, Guangzhou, Chengde, Tangshan, Nanjing, Suzhou, Nanchang, Xi'an

2025-12-09

By invitation

Nimotuzumab Combined With Chemoradiotherapy in the Treatment of Unresectable Locally Advanced or Oligometastatic Pancreatic Cancer

NCT07386704Pancreatic Cancer Non-resectable

DrugNimotuzumab

Peking University First Hospital

Phase 2

Beijing

2025-12-09

Recruiting

TITAN-HCC: Neoadjuvant and Adjuvant QL1706 With TACE in Resectable Hepatocellular Carcinoma Beyond Milan Criteria

NCT07268131Hepatocellular Carcinoma (HCC)

Fudan University

Not applicable

Shanghai

2025-12-09

Recruiting

A Study on a Predictive Model for Efficacy and Prognosis of Pancreatic Carcinoma Based on Multimodal Data

NCT07561814Pancreatic Cancer

Shanghai Zhongshan Hospital

Observational

1,030

Shanghai

2025-12-09

Recruiting

Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

NCT07226999Small Cell Lung Cancer (SCLC)

DrugsPF-08634404·Atezolizumab

Pfizer

Phase 2/3

550

Guangzhou, Shanghai

2025-12-09

Active, closed

Prognostic Model of Elderly Hodgkin Lymphoma in China

NCT07374068Hodgkin Lymphoma

Tianjin Medical University Cancer Institute and Hospital

Observational

400

Tianjin

2025-12-09

Recruiting

A Phase II Clinical Trial of Efficacy and Safety of SAL0140 at Different Doses in Patients With Uncontrolled Hypertension

NCT07654140Uncontrolled Hypertension

DrugSAL0140

Shenzhen Salubris Pharmaceuticals Co., Ltd.

Phase 2

252

Beijing

2025-12-09

Recruiting

A Clinical Study of Glycerol Phenylbutyrate in Chinese Patients With Urea Cycle Disorders

NCT06904027Urea Cycle Disorders

DrugRavicti

Tongji Hospital

Observational

Beijing, Guangzhou, Wuhan, Shanghai, Hangzhou

2025-12-09

Recruiting

A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

NCT07269210Severe Hypertriglyceridemia

Eli Lilly and Company

Phase 2

Beijing, Chengdu, Guangzhou, Luoyang, Shanghai, Xuzhou

2025-12-08

Not yet open

A First-in-Man Clinical Trial to Evaluate the Safety and Feasibility of ICS-Elpis in Patients With Iliac Artery Stenosis or Occlusion Lesions

NCT07290101Iliac Artery Stenosis, Iliac Artery Occlusion

Biotyx Medical (Shenzhen) Co., Ltd.

Not applicable

Shanghai

2025-12-08

Recruiting

Trilaciclib in Patients Receiving Sacituzumab Tirumotecan for EGFR-mutated, Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT06992739NSCLC (Advanced Non-small Cell Lung Cancer), EGFR, Myelosuppression

The First Affiliated Hospital of Xiamen University

Phase 2

Xiamen

2025-12-08

Active, closed

Construction of a Predictive Model for the Efficacy of Chemoprevention Combined With Targeted Therapy in Pancreatic Cancer

NCT07326150Pancreatic Cancer Resectable, Pancreatic Cancer Non-resectable

Zhejiang Cancer Hospital

Observational

Zhejiang

2025-12-08

Active, closed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetic of IBI3011

NCT07295496Acute Gout Flare

Innovent Biologics (Suzhou) Co. Ltd.

Phase 1

Suzhou

2025-12-08

Recruiting

NWRD06 DNA Plasmid for HCC After Curative Resection.

NCT07324304Hepatocellular Carcinoma (HCC)

Newish Technology (Beijing) Co., Ltd.

Phase 2

Beijing, Harbin, Hangzhou

2025-12-08

Recruiting

A Real-world Study on the Influencing Factors of Efficacy of Ruxolitinib Cream in Vitiligo

NCT07153666Vitiligo

DrugRuxolitinib

Peking University Third Hospital

Observational

170

Beijing

2025-12-08

Recruiting

Analysis of Factors Influencing the Quality of Bowel Preparation Before Colonoscopy in IBD Patients

NCT07335705IBD (Inflammatory Bowel Disease), Colonoscopy, Colonoscopy: Bowel Preparation

Changhai Hospital

Observational

1,000

Shanghai

2025-12-08

Not yet open

Characterising the Network-Specific Effects of Piriform Cortex Stimulation Via SEEG

NCT07305311Refractory Epilepsy, Neuromodulation

Xuanwu Hospital, Beijing

Not applicable

Beijing

2025-12-08

Not yet open

Improving Chemotherapy Induced Peripheral Neuropathy in Children With Leukemia: A Study of Transcutaneous Acupoints Electrical Stimulation and Auricular Acupressure Interventions

NCT07279818Chemotherapy Induced Peripheral Neuropathy (CIPN)

The Hong Kong Polytechnic University

Not applicable

132

Shanghai

2025-12-08

Recruiting

Phase III Clinical Trial of SHPL-49 Injection in the Treatment of Acute Ischemic Stroke

NCT07241520Acute Ischemic Stroke

Shanghai Hutchison Pharmaceuticals Limited

Phase 3

1,096

Linfen

2025-12-08

Recruiting

The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephritis Patients for 6 Months Compared With Mycophenolate Mofetil Treatment

NCT07340463Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN)

DrugsBelimumab·Mycophenolate Mofetil·Telitacicept

Nanjing University School of Medicine

Phase 2

Nanjing

2025-12-08

Active, closed

CMTS0515-auWMT for Radiation Enteritis

NCT07331688Radiation Enteritis

The Second Hospital of Nanjing Medical University

Phase 1/2

Nanjing

2025-12-08

Recruiting

Safety and Efficacy of CD19 Chimeric Antigen Receptor T-Cell (CAR-T) in the Treatment of Refractory Membranous Nephropathy

NCT07266181Refractory Membranous Nephropathy

The First Affiliated Hospital of Air Force Medical University

Phase 1

Xi'an

2025-12-08

Recruiting

Efficacy and Safety of Transcranial Temporal Interference Stimulation (tTIS) for Neuropathic Pain in Neuromyelitis Optica Spectrum Disorder (NMOSD)

NCT07377305NMO Spectrum Disorder

Tang-Du Hospital

Not applicable

Xi'an

2025-12-08

Recruiting

A Study of SHR3680, HS-20093 and SHR2554 in Subjects With Prostate Cancer

NCT07230106Prostate Cancer

DrugsRezvilutamide·Ris-Rez·Zeprumetostat·Abiraterone

Jiangsu HengRui Medicine Co., Ltd.

Phase 2

218

Nanjing, Tianjin

2025-12-08

Recruiting

SCAN Targeted Epidural Modulation for Parkinson's Disease

NCT06919822Parkinson Disease

Changping Laboratory

Not applicable

Fuzhou

2025-12-08

Recruiting

Toripalimab Combined With BCG Perfusion for the Treatment of HR-NMIBC After TURBT Surgery Exploration

NCT07307456Bladder Cancer

Changhai Hospital

Phase 2

Shanghai

2025-12-08

Recruiting

Effects of taVNS Combined With Dexmedetomidine on POVN

NCT07271147Postoperative Nausea and Vomiting

DrugDexmedetomidine

Affiliated Hospital of Nantong University

Not applicable

176

Nantong

2025-12-07

Recruiting

Atosiban in Women With Previous Implantation Failure and Abnormal Uterine Contractions

NCT07185230Infertility

DrugAtosiban

Northwest Women's and Children's Hospital, Xi'an, Shaanxi

Not applicable

792

Xi'an

2025-12-06

Recruiting

Phase II Clinical Study of Probiotic LR607 in Patients With Non-Small Cell Lung Cancer

NCT07534033NSCLC Diagnosed by Histology or Cytology, A Multidisciplinary Team Assessment Determined That the Patient Was a Suitable Candidate for Radical Surgical Resection, Overall Lung Function is Adequate for the Planned Lung Resection, AJCC is Classified as IIA-IIIB

Zhujiang Hospital

Phase 2

Guangzhou

2025-12-06

Recruiting

Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Advanced Solid Cancers

NCT07475182Advanced Solid Cancers

Hainan Cancer Hospital

Early Phase 1

Haikou

2025-12-06

Recruiting

Cilostazol for Preventing Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage

NCT07249853Aneurysmal Subarachnoid Hemorrhage

DrugCilostazol

Beijing Tiantan Hospital

Phase 3

380

Beijing

2025-12-06

Active, closed

The Effectiveness and Safety of Hypertonic Citrate Adenine-New (HCA-N) Solution for the Preservation of Kidney Grafts During Kidney Transplantation

NCT07825025Kidney Transplant

Zhongnan Hospital

Phase 2/3

250

Wuhan

2025-12-05

Recruiting

Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management

NCT07346976Neonatal Hyperbilirubinemia

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Not applicable

100

Yiwu

2025-12-05

Recruiting

A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD

NCT07275840Neovascular Age-related Macular Degeneration

DrugIBI302

Innovent Biologics Technology Limited (Shanghai R&D Center)

Phase 2

800

Shanghai

2025-12-05

Recruiting

Endoscopic Skin-Sparing vs. Conventional Mastectomy for Wound Complications in BC

NCT07548762Breast Cancer

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not applicable

258

Guangzhou

2025-12-05

Recruiting

A Phase III Clinical Study of Rezvilutamide in Patients With Metastatic Hormone-Sensitive Prostate Cancer

NCT07241416Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

DrugsEnzalutamide Soft·Rezvilutamide

Jiangsu HengRui Medicine Co., Ltd.

Phase 3

206

Beijing

2025-12-05

Active, closed

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

NCT07211776Thyroid Eye Disease (TED)

DrugVRDN-003

Zai Lab (Shanghai) Co., Ltd.

Phase 3

108

Beijing, Bengbu, Changsha, Chengdu, Chongqing, Dalian, Foshan, Fuzhou

2025-12-05

Active, closed

Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2

NCT07263776Acute Ischemic Stroke

DrugTocilizumab

Capital Medical University

Phase 3

692

Suzhou, Zhangzhou, Qinzhou, Langfang, Qinhuangdao, Tangshan, Harbin, Anyang

2025-12-05

Not yet open

Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

NCT07266155Paroxysmal Nocturnal Hemoglobinuria

DrugLP-005

Longbio Pharma

Phase 2

Nanjing

2025-12-05

Recruiting

A Phase I Study of QLS2309 Injection in Patients With CD70+ Relapsed/Refractory Hematologic Malignancies

NCT07173595Relapsed or Refractory Hematologic Malignancies

Qilu Pharmaceutical Co., Ltd.

Phase 1

186

Beijing

2025-12-05

Recruiting

Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma

NCT07339488Borderline Resectable Carcinoma, Unresectable Cancer, Esophageal Squamous Cell Carcinoma (ESCC), Immune Checkpoint Inhibitor

Chuangzhen Chen

Phase 2

Shantou

2025-12-05

Recruiting

Evaluation of Diaphragmatic Function After Interscalene Block With Liposomal Bupivacaine

NCT07263295Diaphragmatic Function, Metacarpal Fracture, Radius Fracture, Peripheral Nerve Neurolysis

DrugLiposomal bupivacaine

Zhejiang University

Not applicable

120

Hangzhou

2025-12-05

Recruiting

A Trial of SHR0302 Tablets and SHR0302 Base Gel in Patients With Non-segmental Vitiligo

NCT07251595Non-segmental Vitiligo

Jiangsu HengRui Medicine Co., Ltd.

Phase 2

176

Jinan

2025-12-05

Not yet open

Scalp Acupuncture Combined With rTMS for Upper Limb Motor Dysfunction in Stroke: A Brain Network Study

NCT07210944Upper Extremity, Acupuncture Therapy, Stroke, Transcranial Magnetic Stimulation Repetitive

Debiao Kong

Not applicable

Hangzhou

2025-12-05

Recruiting

Clinical Trial of VBC103 in Patients With Advanced Malignant Solid Tumors

NCT07299747Participants With Advanced Solid Tumor Malignancies

VelaVigo Bio Inc

Phase 1/2

255

Shanghai

2025-12-04

Recruiting

A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

NCT07221253Biliary Tract Cancer

DrugsGemcitabine/Cisplatin·Rilvegostomig·Durvalumab

AstraZeneca

Phase 3

1,100

Beijing, Changchun, Changde, Changsha, Chengdu, Fuzhou, Guangzhou, Hangzhou

2025-12-04

Recruiting

Association Between Clinical Classification and Prognosis in Chronic Radiation Enteropathy

NCT07378631Radiotherapy, Radiation Proctitis, Radiation Enteritis

Sixth Affiliated Hospital, Sun Yat-sen University

Observational

150

Guangzhou

2025-12-04

Recruiting

A Mixed Cohort, Multicentre Exploratory Study of Non-invasive Quantitative Assessment of Renal Graft Function With Non-contrast Functional Magnetic Resonance Imaging

NCT07333495Kidney Transplant, Renal Allograft Recipients, Renal Allograft

Tongji Hospital

Observational

1,000

Shiyan, Wuhan, Taiyuan

2025-12-04

Recruiting

A Trial of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer

NCT07232849Lung Cancer

DrugHRS-4508

Jiangsu HengRui Medicine Co., Ltd.

Phase 2

100

Shanghai, Hangzhou

2025-12-04

Recruiting

Phase III Study to Compare GFH375 and Chemotherapy in Patients With KRAS G12D-Mutant Metastatic Pancreatic Cancer

NCT07262567Metastatic Pancreatic Cancer

DrugCetuximab

Genfleet Therapeutics (Shanghai) Inc.

Phase 3

320

Beijing

2025-12-04

Recruiting

A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)

NCT07209111Neoplasm Malignant

DrugsCalderasib·Cetuximab

Merck Sharp & Dohme LLC

Phase 2

150

Beijing, Xiamen, Guangzhou, Harbin, Wuhan, Changsha, Nanjing, Nanchang

2025-12-04

Active, closed

A Clinical Study to Evaluate GK01 Cell Injection in Combination With PD-1 Monoclonal Antibody for Advanced Solid Tumors

NCT07407985Solid Tumors

Tianjin Medical University Cancer Institute and Hospital

Phase 1

Tianjin

2025-12-04

Recruiting

A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

NCT07250802Plaque Psoriasis

DrugZasocitinib

Takeda

Phase 3

110

Beijing, Guangzhou, Changsha, Hangzhou, Shanghai

2025-12-04

Recruiting

Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin

NCT07283835Non Muscle Invasive Bladder Cancer, High-grade Ta/ T1 Papillary Disease Bladder Cancer

DrugCretostimogene Grenadenorepvec

Lepu Biopharma Co., Ltd.

Phase 2

Beijing, Chongqing, Fuzhou, Wuhan, Changsha, Nanjing, Shenyang, Jinan

2025-12-04

Recruiting

A Clinical Trial Testing the Safety of Pumitamig (an Investigational Drug) and How Well it Works When Combined With Chemotherapy for People Who Have Not Been Treated Yet for Pancreatic Cancer

NCT07255404Pancreatic Ductal Adenocarcinoma (PDAC)

DrugsMFOLFIRINOX·Pumitamig·Nab-paclitaxel·Gemcitabine

BioNTech SE

Phase 2

105

Beijing, Changchun, Chengdu, Dalian, Guangzhou, Hangzhou, Jinan, Kunming

2025-12-04

Recruiting

First-Line Jaktinib for Acute Graft-Versus-Host Disease (aGVHD)

NCT07285889Acute Graft Versus Host Disease

First Affiliated Hospital of Zhejiang University

Phase 1/2

Hangzhou

2025-12-03

Recruiting

Exploratory Clinical Study of Second-generation CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in Treating Paediatric B Cell-related Autoimmune Diseases

NCT07283315Paediatric B Cell-related Autoimmune Diseases, Autoimmune Diseases, CAR

The Children's Hospital of Zhejiang University School of Medicine

Early Phase 1

Hangzhou

2025-12-03

Recruiting

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

NCT07276399Squamous Cell Carcinoma of Head and Neck

DrugsAmivantamab·Cisplatin·Carboplatin·Pembrolizumab

Janssen Research & Development, LLC

Phase 3

600

Beijing, Bengbu, Changsha, Chengdu, Chongqing, Dongguan, Guangzhou, Hangzhou

2025-12-03

Recruiting

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

NCT07371663Solid Cancers, NSCLC (Advanced Non-small Cell Lung Cancer), Gastric (Stomach) Cancer, Endometrial Cancer

Beijing Tide Pharmaceutical Co., Ltd

Phase 1/2

266

Beijing, Zhengzhou, Hangzhou

2025-12-03

Recruiting

A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)

NCT07244341Metastatic Castration-resistant Prostate Cancer

DrugsValemetostat·Darolutamide

Daiichi Sankyo

Phase 1

Guangzhou, Shanghai, Wenzhou

2025-12-03

Recruiting

A Study of AND017 to Evaluate Efficacy and Safety in Patients With Anemia Due to Non-Dialysis-Dependent Chronic Kidney Disease (NDD-CKD)

NCT07487727Anemia Due to Chronic Kidney Disease

DrugAND017

Kind Pharmaceuticals LLC

Phase 3

240

Beijing

2025-12-03

Recruiting

Efficacy and Safety of PCSK9 Inhibitors in Patients With Large-Artery Atherosclerosis (LAA) Ischemic Stroke

NCT07540741Acute Ischemic Stroke

First Affiliated Hospital of Harbin Medical University

Observational

1,000

Heilongjiang

2025-12-03

Recruiting

A Clinical Study Evaluating the Preliminary Anti-tumor Efficacy and Safety of Hemay181

NCT07446816Advanced Solid Tumors

DrugHemay181

Ganzhou Hemay Pharmaceutical Co., Ltd

Phase 1

Xinxiang

2025-12-03

Recruiting

Clinical Study of LV009 Injection for the Treatment of Hematologic and Lymphoid Malignancies

NCT07284927Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia

DrugLV009

PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Phase 1

Suzhou

2025-12-03

Recruiting

A Phase I/II Clinical Study of SHR-4298 Injection in Patients With Malignant Solid Tumors

NCT07229612Malignant Solid Tumors

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Phase 1/2

200

Guangzhou

2025-12-03

Recruiting

Balloon Guide Catheter Combined With Filter Protection for Carotid Artery Stenting

NCT07247864Carotid Artery Stenosis

Beijing Anzhen Hospital

Not applicable

296

Beijing

2025-12-03

Recruiting

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

NCT06979453Plaque Psoriasis

DrugDeucravacitinib

Bristol-Myers Squibb

Phase 3

366

Beijing, Guangzhou, Shenzhen, Handan, Zhengzhou, Changsha, Jinan, Shanghai

2025-12-03

Recruiting

Serplulimab for Locally Advanced Cervical Cancer

NCT07340489Cervical Cancer

DrugSerplulimab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

216

Tianjin

2025-12-03

Recruiting

A Study to Evaluate Efficacy and Safety of IBI112 in Adolescent Participants With Moderate to Severe Plaque Psoriasis

NCT07265284Psoriasis

Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.

Phase 3

104

Beijing

2025-12-03

Recruiting

Influenza Vaccination After Acute Coronary Syndrome

NCT07259252Acute Coronary Syndromes (ACS)

DrugInfluenza vaccine

Tongji Hospital

Not applicable

6,620

Wuhan

2025-12-03

Recruiting

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

NCT07218926Gastrointestinal Neoplasms

DrugsIDRX-42·Sunitinib

GlaxoSmithKline

Phase 3

450

Shijiazhuang, Shanghai, Beijing, Chengdu, Chongqing, Guangzhou, Hangzhou, Jinan

2025-12-03

Recruiting

Irinotecan Hydrochloride Liposome Injection (II)in Combination With Oxaliplatin, 5-FU/LV Versus AG for First-line Treatment of Metastatic Pancreatic Cancer

NCT07238283First-line Treatment of Metastatic Pancreatic Cancer

Drugs5Fluorouracil·Irinotecan Hydrochloride Liposome·Calcium folinate·Nab-paclitaxel

Jiangsu HengRui Medicine Co., Ltd.

Phase 3

662

Beijing

2025-12-02

Recruiting

A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

NCT06807281Atopic Dermatitis

DrugAbrocitinib

Pfizer

Phase 3

450

Beijing, Shenzhen, Changsha, Nanchang, Hangzhou, Shanghai

2025-12-02

Recruiting

PTC-Guided Therapy for Peritoneal Mesothelioma

NCT07330271Peritoneal Mesothelioma

Beijing Tsinghua Chang Gung Hospital

Not applicable

347

Beijing

2025-12-02

Not yet open

Auricular Acupressure Reduces Rebound Effects After Discontinuation of Atropine

NCT07129889Myopia

Ningbo Eye Hospital

Not applicable

180

Ningbo

2025-12-02

Recruiting

A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)

NCT07116031Chronic Graft Versus Host Disease

DrugBelumosudil

Sanofi

Phase 2

Beijing, Shanghai, Shenzhen, Suzhou

2025-12-02

Recruiting

Clinical Trial Comparing TQB2868 Injection Combined With Anlotinib Hydrochloride Capsules With Placebo Combined With Chemotherapy as First-line Treatment for Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)

NCT07165951Metastatic Pancreatic Ductal Adenocarcinoma

DrugsTQB2868·Anlotinib hydrochloride·Gemcitabine·Paclitaxel

Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.

Phase 3

566

Hefei, Beijing, Chongqing, Fuzhou, Xiamen, Lanzhou, Guangzhou, Shenzhen

2025-12-02

Recruiting

A Study of SHR-7367 With Anti-tumor Agents in Patients With Solid Tumors

NCT07229586Solid Tumor

DrugsAdebrelimab·Gemcitabine·Paclitaxel

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 1/2

100

Tianjin

2025-12-02

Recruiting

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

NCT07201558Rheumatoid Arthritis, Systemic Lupus Erythematosus

DrugSurovatamig

AstraZeneca

Phase 1

Beijing, Chengdu, Nanjing

2025-12-02

Recruiting

FAPI PET Imaging in Nonischemic Cardiomyopathy

NCT07878338Nonischemic Cardiomyopathy

Peking Union Medical College Hospital

Phase 2

400

Beijing

2025-12-02

Recruiting

Treponemal Shedding, Load, and Viability, in Women and Men-who-have-sex-with-women-only With Early Infectious Syphilis: Implications for Transmission

NCT07300254Syphilis

Monash University

Observational

480

Shanghai

2025-12-02

Recruiting

A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis

NCT07578220Ankylosing Spondylitis

China-Japan Friendship Hospital

Not applicable

Henan

2025-12-02

Recruiting

Study of ZG005 in Combination With Platinum-Based Chemotherapy in Participants With Advanced Biliary Tract Carcinoma

NCT07099547Biliary Tract Carcinoma

DrugsZG005·Tislelizumab·Gemcitabine·Cisplatin

Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Phase 2

Hefei

2025-12-02

Active, closed

A Study of DII235 in Adults With Elevated Lipoprotein(a)

NCT07235046Lipoprotein Disorder

Novartis Pharmaceuticals

Phase 2

234

Luoyang, Shenyang, Wenzhou, Beijing

2025-12-02

Recruiting

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

NCT06937229Alzheimer Disease, Agitation

DrugsKarX-EC·KarXT

Bristol-Myers Squibb

Phase 3

650

Beijing, Haidian District, Guangzhou, Shenzhen, Changsha, Nanjing, Tianjin, Hangzhou

2025-12-02

Not yet open

For Patients With Myocardial Infarction and Multiple Vessel: Testing if Ultrasound (UFR) Can Guide All Needed Treatment in One Procedure, Avoiding a Return Hospital Visit for a Second Operation.

NCT07264881Microvascular Obstruction (MVO), Multivessel Coronary Artery Disease, ACS (Acute Coronary Syndrome), ST Elevation Myocardial Infarction (STEMI)

Beijing Anzhen Hospital

Observational

200

Beijing

2025-12-02

Recruiting

A Study of LBL-024 in Combination With Paclitaxel ± Bevacizumab for the Treatment of Platinum-resistant Ovarian Cancer

NCT07042802Ovarian Cancer

DrugsLBL-024·Paclitaxel·Bevacizumab

Nanjing Leads Biolabs Co.,Ltd

Phase 1/2

180

Beijing, Fuzhou, Guangzhou, Harbin, Anyang, Zhengzhou, Xuzhou, Shenyang

2025-12-02

Recruiting

A Phase I Clinical Trial to Evaluate HECN30227 Injection in Healthy Subjects and Subjects With Chronic Hepatitis B

NCT07771140HBV Infection

Sunshine Lake Pharma Co., Ltd.

Phase 1

Hefei

2025-12-02

Not yet open

Mecobalamin in Promoting Recurrent Laryngeal Nerve Function Recovery After Thyroid Surgery

NCT07274696Patients Undergoing Open Thyroid Surgery

DrugMecobalamin

West China Hospital

Phase 3

528

Chengdu

2025-12-01

Not yet open

Safety and Quality of Life of Three Treatment Strategies for Low-Risk Papillary Thyroid Microcarcinoma

NCT07249125Papillary Thyroid Microcarcinoma

Xijing Hospital

Observational

1,630

Xi'an

2025-12-01

Recruiting

TALENT Study: Phase II Trial of Adjuvant L-TIL Plus Tislelizumab in Resectable NSCLC Without pCR After Neoadjuvant Chemoimmunotherapy

NCT07330037NSCLC

DrugTislelizumab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2025-12-01

Not yet open

Intravenous Tirofiban After Delayed Thrombolysis in Stroke

NCT07111806Acute Ischemic Stroke

DrugTirofiban

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase 3

852

Guangzhou

2025-12-01

Not yet open

The Effect of Immersive Virtual Reality Treatment With Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder

NCT04534907Obsessive-Compulsive Disorder, Virtual Reality

Shanghai Mental Health Center

Not applicable

Shanghai

2025-12-01

Recruiting

Eye-Brain-Kidney in CKD

NCT07358572Chronic Kidney Diseases

Beijing Friendship Hospital

Observational

1,500

Beijing

2025-12-01

Recruiting

Active Locomotion of Magnetically Controlled Capsule Endoscopy in the Small Bowel: A Feasibility Study

NCT07325344Capsule Endoscopy

Shandong University

Not applicable

Jinan

2025-12-01

Recruiting

Mobilization of Stem Cells With Motixafortide (BL-8040) in Combination With G-CSF in Multiple Myeloma Patients

NCT06514508Multiple Myeloma

DrugsMotixafortide·G-Csf

Guangzhou Gloria Biosciences Co., Ltd.

Phase 3

Beijing, Harbin

2025-12-01

Active, closed

A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of SHR-1139 in Patients With Moderate-to-severe Active Ulcerative Colitis

NCT07232576Adult Patients With Moderately to Severely Active Ulcerative Colitis

DrugSHR-1139

Guangdong Hengrui Pharmaceutical Co., Ltd

Phase 2

Guangzhou

2025-12-01

Recruiting

Prevention of Atrial Fibrillation After Cardiac Surgery by Pericardiotomy

NCT06728826Atrial Fibrillation (AF), Cardiac Events, Pericardial Effusion

Changhai Hospital

Not applicable

650

Shanghai

2025-12-01

Recruiting

Evaluation of the Effect of Cordycepin on CD8+ Lymphocytopenia in Patients With Solid Tumors

NCT07258160Solid Cancer, Lymphopenia

Second Affiliated Hospital of Soochow University

Phase 2

127

Suzhou

2025-12-01

Active, closed

AI Multimodal Model for Liver Cancer Diagnosis and Prognosis

NCT07658586Liver Cancer, Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma (Icc)

Guangxi Medical University

Observational

600

Nanning

2025-12-01

Recruiting

SCRT(Short Course Radiotherapy) Combined With CAPOX Plus QL1706 for Rectal Cancer Liver Metastases

NCT06787183Locally Advanced Rectal Cancer With Liver Metastases

DrugsLenvatinib·Capecitabine·Oxaliplatin

Fujian Cancer Hospital

Phase 2

Fuzhou

2025-12-01

Recruiting

MPR for Stroke Risk Assessment of ICAS

NCT07309718ICAS - Intracranial Atherosclerosis, Stroke Ischemic, Hemodynamic

Xuanwu Hospital, Beijing

Observational

400

Beijing

2025-12-01

Recruiting

A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County)

NCT07755384Reflux Esophagitis

Jilin University

Observational

Yushu

2025-12-01

Active, closed

Digital Angiography-Derived Fractional Flow Assessment for Intracranial Stenosis

NCT07309705Intracranial Atherosclerosis ICAS, Hemodynamic, Stroke

Xuanwu Hospital, Beijing

Observational

400

Beijing

2025-12-01

Not yet open

Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of Secukinumab in HS

NCT07261072Hidradenitis Suppurativa (HS), Hidradenitis Suppurativa (Acne Inversa), Secukinumab

DrugSecukinumab

Peking Union Medical College

Phase 4

Nanjing

2025-12-01

Not yet open

EFG vs IVIG in TAMG

NCT07231523Efgartigimod, Intravenous Immunoglobulin, Myasthenia Gravis Associated With Thymoma

Shanghai Zhongshan Hospital

Phase 3

Shanghai

2025-12-01

Recruiting

DV+BCG in HER2-Expressing, BCG-Naïve High-Risk NMIBC

NCT07207824Bladder (Urothelial, Transitional Cell) Cancer, NMIBC

Fudan University

Phase 3

182

Shanghai

2025-12-01

Recruiting

Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty

NCT07319546Knee Osteoarthristis, Arthroplasties, Knee Replacement

Mahidol University

Not applicable

Dali

2025-12-01

Recruiting

Prediction of Outcome to Neoadjuvant Therapy in Non-small Cell Lung Cancer（NSCLC）

NCT07388771NSCLC, Neoadjuvant Therapy

Qian Chu

Observational

500

Wuhan, Hangzhou

2025-12-01

Recruiting

Acute Treatment of Vestibular Migraine by Rimegepant

NCT07871097Vestibular Migraine

Wensheng Qu

Phase 4

Wuhan

2025-12-01

Recruiting

Safety and Efficacy of Fruquintinib Plus Nab-Paclitaxel and Iparomlimab and Tuvonralimab Injection in the Second-Line Treatment for Immunotherapy-experienced Advanced Gastric Cancer

NCT07392346Gastric Cancer Adenocarcinoma Metastatic

DrugsIparomlimab and Tuvonralimab·Fruquintinib·Paclitaxel

Dai, Guanghai

Phase 2

Beijing

2025-12-01

Recruiting

Treatment Outcomes and Complications of Three Therapeutic Approaches for Concomitant Choledocholithiasis and Cholecystolithiasis

NCT07413068Cholelithiasis Associated With Common Bile Duct Stones

Qilu Hospital of Shandong University

Observational

300

Jinan

2025-12-01

Recruiting

A Phase 3 Study of Sunvozertinib Versus Placebo as Adjuvant Therapy in Patients With Early-Stage Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations or PACC Mutations After Radical Surgery

NCT07182682Non-Small Cell Lung Cancer

DrugSunvozertinib

Dizal (Jiangsu) Pharmaceutical Co., Ltd.

Phase 3

360

Beijing, Changchun, Changsha, Chengdu, Fuzhou, Guangzhou, Hangzhou, Harbin

2025-12-01

Recruiting

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat Glomerulonephritis

NCT05517980Glomerulonephritis

Kira Pharmacenticals (US), LLC.

Phase 2

Beijing

2025-12-01

Recruiting

Personalized KXV01 Lentinvivo (TCR) Injection as the Therapy for Advanced Solid Tumors

NCT07275853Advanced Solid Tumors

DrugKXV01 TCR Lentinvivo

TCRx Therapeutics Co.Ltd

Phase 1

Beijing

2025-12-01

Recruiting

Intelligent Management Platform for Guiding Exercise Rehabilitation in Coronary Heart Disease Patients

NCT07259278Secondary Prevention of Coronary Heart Disease

China National Center for Cardiovascular Diseases

Not applicable

200

Beijing

2025-12-01

Recruiting

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Cervicogenic Headache

NCT07347730Myofascial Trigger Points, Cervicogenic Headache, Dorsal Root Ganglion

Beijing Tiantan Hospital

Not applicable

1,036

Beijing

2025-12-01

Not yet open

Effect of Roxadustat on Heart Failure Patients With Anaemia and Moderate-to-Severe Chronic Kidney Disease

NCT07268807Heart Failure, CKD, Anemia

DrugRoxadustat

Zhongda Hospital

Observational

200

Nanjing

2025-12-01

Recruiting

Niaoduqing Granules in Older Adults With Impaired Kidney Function

NCT07741292Chronic Kidney Disease

Huashan Hospital

Phase 4

300

Shanghai

2025-12-01

Not yet open

A Randomized Trial of Surgical Decision-Making Guided by TDTP-RECIST

NCT07208526Intrahepatic Cholangiocarcinoma (Icc), Conversion Therapy, TDTP-RECIST, GOLP Regimen

Shanghai Zhongshan Hospital

Not applicable

270

Shanghai

2025-12-01

Not yet open

A Phase II Study of QL1706 and Platinum-Based Chemotherapy in Patients With SMARCA4-Deficient, Locally Advanced or Metastatic Non-Small Cell Lung Cancer.

NCT07200947SMARCA4-Deficient Tumor, Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Zhijie Wang

Phase 2

Beijing

2025-12-01

Recruiting

Interleukin-23 Monoclonal Antibody for Inflammatory Bowel Disease: Efficacy and Safety

NCT07216014Crohn's Disease and Ulcerative Colitis

DrugInterleukin 23

Sixth Affiliated Hospital, Sun Yat-sen University

Phase 4

200

Guangzhou

2025-12-01

Not yet open

Efficacy and Safety Evaluation of Non-invasive Temporal Interference Stimulation for Blood Pressure Regulation

NCT07239492Hypertension, Hypotension

Xuanwu Hospital, Beijing

Not applicable

Beijing

2025-12-01

By invitation

Effects of tDCS on Fear Reversal in Patients With Anxiety Disorders

NCT07405463Anxiety Disorders

Jingchu Hu

Not applicable

140

Guangzhou

2025-12-01

Recruiting

WAST Cell-Docetaxel Combination Therapy in PD-1 Inhibitor-Resistant Advanced NSCLC

NCT07330050NSCLC (Non-small Cell Lung Cancer)

DrugDocetaxel

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2025-12-01

Recruiting

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Shoulder Osteoarthritis(OA)

NCT07347054Myofascial Trigger Points, Chronic Musculoskeletal Pain, Shoulder Osteoarthritis

Beijing Tiantan Hospital

Not applicable

1,036

Beijing

2025-12-01

Not yet open

Enhanced Prediction Model for Major Adverse Events Following Acute Myocardial Infarction

NCT07250152Myocardial Infarction (MI)

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

1,544

Hangzhou

2025-12-01

Recruiting

Clinical Study of LILRA6 CAR-T for the Treatment of R/R Acute Myeloid Leukemia

NCT07263906Refractory Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 1

Hangzhou

2025-12-01

Recruiting

Association Between Preoperative Metformin Exposure and Postoperative Nausea and Vomiting in Patients Undergoing General Anesthesia

NCT07244575Postoperative Nausea and Vomiting

Sixth Affiliated Hospital, Sun Yat-sen University

Observational

909

Guangzhou

2025-12-01

Not yet open

Exploratory Study of Intranasal Administration of Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles for the Treatment of Ischemic Stroke

NCT07232563Ischemic Stroke

Zhujiang Hospital

Phase 1

Guangzhou

2025-12-01

Recruiting

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Hip Osteoarthritis(OA)

NCT07347041Myofascial Trigger Points, Chronic Musculoskeletal Pain, Hip Osteoarthritis

Beijing Tiantan Hospital

Not applicable

1,036

Beijing

2025-12-01

Recruiting

A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

NCT07241390Atherosclerosis Cardiovascular Disease, Chronic Kidney Disease

DrugOrforglipron

Eli Lilly and Company

Phase 3

7,140

Beijing, Changchun, Changde, Changzhou, Chengdu, Chongqing, Dalian, Guangzhou

2025-12-01

By invitation

Intervention of Ovarian Cancer With Antigen-specific Engineered Immune Effectors

NCT03393962Ovarian Cancer

Shenzhen Geno-Immune Medical Institute

Phase 1/2

Shenzhen

2025-12-01

Recruiting

STROKE 120 ACTION Trial

NCT07135310Ischemic Stroke

Shanghai Minhang Central Hospital

Not applicable

1,696,000

Shanghai

2025-12-01

Recruiting

Short-Course Definitive Chemoradiotherapy Combined With Adjuvant or Concurrent Plus Adjuvant Camrelizumab for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

NCT07530094Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

DrugCamrelizumab

Ning Jiang, M.D./Ph.D.

Phase 2

Nanjing

2025-12-01

Recruiting

Asiaticoside for Treating Overweight/Obesity

NCT07241533Overweight , Obesity

Shanghai Zhongshan Hospital

Not applicable

Shanghai

2025-12-01

Recruiting

Valsalva SBP Drop and LVOT Obstruction

NCT07483125HCM, oHCM, nHCM

Shanghai Zhongshan Hospital

Observational

800

Shanghai

2025-12-01

Recruiting

DEB-TACE vs cTACE in HCC After TIPS

NCT07322848Hepatocellular Carcinoma (HCC), TACE, TIPS, DEB-TACE

First Affiliated Hospital, Sun Yat-Sen University

Phase 3

206

Guangzhou

2025-12-01

Active, closed

Safety and Efficacy of Combining a Vitamin B6-Limited Diet With Immunotherapy in Solid Tumor Patients: A Clinical Study Protocol

NCT07257497Solid Tumor Cancer

West China Hospital

Phase 1

Chengdu

2025-12-01

Not yet open

A Nationwide Multicenter, Single-arm, Retrospective Study of Delayed Endoscopic DTI-BR After Simple Mastectomy

NCT07257003Breast Cancer

Du Zhenggui

Not applicable

150

Chengdu

2025-12-01

Recruiting

Individualized Application of Anti-Thymocyte Globulin(ATG)in Unrelated Donor Hematopoietic Stem Cell Transplantation

NCT07648992Hematopoietic Stem Cell Transplantation

DrugAnti-Thymocyte Globulin

Daihong Liu

Phase 4

324

Beijing

2025-12-01

Active, closed

Research on the Application of Decision Tree in Child Life

NCT07325890Psychosocial Intervention, Non-Randomized Controlled Trials

Children's Hospital of Fudan University

Not applicable

Shanghai

2025-12-01

Recruiting

Diagnostic Value of 68Ga-Pentixafor PET/CT in Adrenal Tumors With Aldosterone and Cortisol Cosecretion

NCT07605156Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion

Peking University First Hospital

Observational

130

Beijing

2025-12-01

Not yet open

Allogeneic UCB-derived CAR-T for B-ALL

NCT07256353B-Cell Acute Lymphoblastic Leukemia, Adult

The General Hospital of Western Theater Command

Early Phase 1

Chengdu

2025-12-01

Not yet open

A RCT of Moist Ag Dressing in Chronic Wound

NCT07235254Chronic Wound, Hard to Heal Wounds, Dressing, Wound he'a'Ling

Peking University Third Hospital

Not applicable

Beijing

2025-12-01

Recruiting

Using Mobile Technology-assisted Outpatient Maintenance Therapy Pediatric ALL

NCT07278882Pediatric Acute Leukemia

Institute of Hematology & Blood Diseases Hospital, China

Not applicable

100

Tianjin

2025-12-01

Recruiting

Construction and Application of an IDH Mutation-Targeted PET/MRI Imaging Framework for Precision Diagnosis of Gliomas

NCT07405372Glioma

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Observational

Chongqing

2025-12-01

Recruiting

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Migraine

NCT07347067Myofascial Trigger Points, Chronic Migraine Headache, Greater Occipital Nerve Block

Beijing Tiantan Hospital

Not applicable

1,036

Beijing

2025-12-01

Not yet open

Sequential rhTPO and Eltrombopag Following Glucocorticoids for Severe Adult ITP

NCT07189910Primary Immune Thrombocytopenia (ITP)

DrugEltrombopag

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 4

150

Wuhan

2025-12-01

Recruiting

Study on the Therapeutic Effect of Different Infusion Times of Tislelizumab on Postoperative High-risk Hepatocellular Carcinoma

NCT07243691Hepatocellular Carcinoma

DrugTislelizumab

Sir Run Run Shaw Hospital

Not applicable

Hangzhou

2025-12-01

Recruiting

Clinical Treatments in Specialized Diseases of Laryngeal Carcinoma (LC) and Hypopharyngeal Carcinoma (HPC)

NCT04908696Glottic Carcinoma, Supraglottic Carcinoma, Subglottic Carcinoma, Pyriform Sinus Carcinoma

Eye & ENT Hospital of Fudan University

Observational

1,000

Shanghai

2025-12-01

Recruiting

The Power of Belief: Expectation-driven and Placebo Modulation of Empathic Pain

NCT07367672Healthy Participants

University of Electronic Science and Technology of China

Not applicable

120

Chengdu

2025-12-01

By invitation

Application of an AI-Based Health Management System in Long-Term Epilepsy Management in Rural Areas

NCT07448233Epilepsies, Remote Management of Epilepsy in Rural Areas

Xijing Hospital

Not applicable

Xi'an

2025-12-01

Recruiting

PRaG-1 Plus PRaG Therapy in in Elderly Patients With Advanced Solid Tumors: A Prospective Clinical Trial (PRaG 10.0)

NCT07267234Solid Cancer, Lymphopenia, Radiotherapy, Immune Checkpoint Inhibitor

Second Affiliated Hospital of Soochow University

Phase 2

Suzhou

2025-12-01

Not yet open

Trifluridine/Tipiracil Plus Fruquintinib vs. Trifluridine/Tipiracil Plus Bevacizumab in Refractory Metastatic Colorectal Cancer: A Randomized, Controlled, Open-Label, Non-Inferiority Trial

NCT07261709Refractory Metastatic Colorectal Cancer

DrugsTrifluridine/Tipiracil·Fruquintinib·Bevacizumab

Sun Yat-sen University

Phase 2

236

Guangzhou

2025-12-01

Recruiting

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease

NCT07305116Autoimmune Diseases, Systemic Lupus Erthematosus (SLE), Multi-Drug Resistant Nephrotic Syndrome, IgA Nephropathy (IgAN)

The Children's Hospital of Zhejiang University School of Medicine

Phase 1

Hangzhou

2025-12-01

Recruiting

Impact of Emotional Status on Prognosis of Patients With BCLC Stage B/C Hepatocellular Carcinoma Undergoing Hepatic Arterial Infusion Chemotherapy Combined With Targeted and Immunotherapy

NCT07436845Hepatocellular Carcinoma (HCC), Emotional Distress, HAIC(Hepatic Artery Infusion Chemotherapy), Immunotherapy

Nanfang Hospital, Southern Medical University

Observational

Guangzhou

2025-12-01

Recruiting

Evaluating the Efficacy and Safety of AI Localization Models in Multidisciplinary Team Care for NSCLC

NCT07626736Nonsmall Cell Lung Cancer

Wen-zhao ZHONG

Not applicable

300

Guangzhou

2025-12-01

Not yet open

Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BLMZ Chinese Cohort

NCT07268664Rifampicin Resistant Tuberculosis, Pulmonary Tuberculosis, Tuberculosis, Drug-resistant Tuberculosis

Beijing Chest Hospital

Phase 3

120

Aksu, Hetian, Kashgar

2025-12-01

Not yet open

Autologous Bedside CD19 CAR T-cell Therapy for B-ALL

NCT07277504B-Cell Acute Lymphoblastic Leukemia, Adult

The General Hospital of Western Theater Command

Early Phase 1

Chengdu

2025-12-01

By invitation

Evaluation of the Efficacy and Safety of Palmitoleic Acid Oil Composition in Preventing Pressure Injuries

NCT07547254Pressure Ulcer Prevention

Ruijin Hospital

Not applicable

Shanghai

2025-12-01

Recruiting

A Phase 1/1b Study to Evaluate Safety, Tolerability and Pharmacokinetics of ZL-1503 in Healthy Volunteers and Participants With Moderate to Severe Atopic Dermatitis

NCT07235384Atopic Dermatitis (AD)

Zai Lab (Shanghai) Co., Ltd.

Phase 1

Beijing, Fuzhou, Nanchang, Jinan, Shanghai, Hangzhou

2025-12-01

Not yet open

Evaluating the Safety and Effectiveness of a Vascular Interventional Robotic System in Assisting With Percutaneous Coronary Intervention Procedures: A Prospective, Multicenter, Randomized Controlled Clinical Trial

NCT07233317Coronary Artery Disease

China National Center for Cardiovascular Diseases

Not applicable

170

Beijing

2025-12-01

Recruiting

Venetoclax as Consolidation in CLL Patients Treated With BTK Inhibitor Monotherapy

NCT06958705Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL)

DrugsIbrutinib·Acalabrutinib·Orelabrutinib·Zanubrutinib

The First Affiliated Hospital with Nanjing Medical University

Phase 2

Nanjing

2025-12-01

Recruiting

Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

NCT07435454Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

Jiangsu Cancer Institute & Hospital

Phase 2

Nanjing

2025-12-01

Recruiting

Safety and Tolerability Study of a Novel Bioartificial Liver in Liver Failure and Small-for-Size Syndrome

NCT07312864Liver Failure, Small-for-Size Syndrome

Beijing Friendship Hospital

Phase 1/2

Beijing

2025-12-01

By invitation

Survival Analysis of Surgical Resection Versus Observation in Patients With Initially uHCC Achieving CR After Systemic Therapy

NCT07290764Hepatocellular Carcinoma

Fujian Provincial Hospital

Observational

729

Fuzhou

2025-12-01

Recruiting

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

NCT07227012Carcinoma, Hepatocellular, Hepatocellular Cancer, Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma

DrugsPF-08634404·Yervoy·Ipilimumab

Pfizer

Phase 1/2

138

Shanghai

2025-12-01

Not yet open

A Phase Ⅰ/Ⅱa Study of SNUG01 in Adult Subjects With ALS

NCT07169175Amyotrophic Lateral Sclerosis (ALS)

DrugSNUG01

SineuGene Therapeutics Co., Ltd.

Phase 1/2

Beijing, Fuzhou, Hangzhou

2025-12-01

Not yet open

Drain Removal on Postoperative Safety and Patient Satisfaction in R-E-NSM With Prepectoral DIBR

NCT07237828Breast Cancer

Du Zhenggui

Not applicable

379

Chengdu

2025-12-01

Recruiting

Multicenter Randomized Controlled Trial (RCT) and Efficacy Evaluation System Study on Surgical Innovation Strategies for Neonatal Complex Congenital Heart Disease

NCT07363538Complex Congenital Heart Disease

Central China Fuwai Hospital of Zhengzhou University

Not applicable

738

Beijing, Chongqing, Guangzhou, Zhengzhou, Wuhan, Changsha, Nanjing, Qingdao

2025-12-01

Not yet open

Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder Cancer

NCT07261592Bladder Cancer, Histone Deacetylase Inhibitor, Entinostat, Chemotherapy

DrugEntinostat

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 1/2

Nanjing

2025-12-01

Recruiting

Biomarkers in Bone Marrow Supernatant for Predicting AML Chemosensitivity

NCT07587944AML, Adult

Fujian Medical University Union Hospital

Observational

405

Fuzhou

2025-12-01

Recruiting

Clinical Efficacy and Mechanism Exploration of MR-61 in Delaying the Progression of Myopia

NCT07298824Myopia Progressing

Second Affiliated Hospital of Nanchang University

Phase 2

164

Nanchang

2025-12-01

Not yet open

RaSOLVE: 125I Radioactive Seed Marking Effects on Pathological Complete Response Rate and Prognosis Post-Neoadjuvant Therapy in Early/Advanced Breast Cancer

NCT07269691Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer

Pengfei Qiu

Phase 3

194

Jinan

2025-12-01

Not yet open

Neoadjuvant Ivonescimab Plus Chemotherapy Followed by Concurrent Chemoradiotherapy in High-Risk Locally Advanced Cervical Cancer

NCT07244965LOCALLY ADVANCED CERVICAL CANCERS

DrugIvonescimab

Women's Hospital School Of Medicine Zhejiang University

Phase 2

Hangzhou

2025-12-01

Recruiting

Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound

NCT07357571Thyroid Papillary Carcinoma, Contrast Enhanced Ultrasound

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Observational

600

Guangdong, Guangzhou

2025-12-01

Recruiting

Phase 1 Study of Chemotherapy Plus HLA-mismatched GPBMC Infusion Bridging to Allo-HSCT for R/R Leukemia

NCT07297173Relapsed Leukemia, Refractory Leukemia

Beijing 302 Hospital

Phase 1

Beijing

2025-12-01

Recruiting

Synthetic PET From CT Improves Precision Diagnosis and Treatment of Lung Cancer: a Prospective, Observational, Multicenter Study

NCT07243873Lung Cancer, PET-CT

Shanghai Pulmonary Hospital, Shanghai, China

Observational

10,000

Zunyi, Jiangxi, Shanghai, Ningbo

2025-12-01

Recruiting

A Phase II Study of Pirfenidone Plus PD-1 Inhibitor With or Without Hypofractionated Radiotherapy for Refractory pMMR/MSS Colorectal Cancer

NCT07644286Colorectal Cancer (CRC)

DrugPirfenidone

Tao Zhang

Phase 2

Wuhan

2025-12-01

Recruiting

A Trial of Shengmai Liquid for Long COVID Fatigue.

NCT06980636Long COVID Fatigue

Beijing University of Chinese Medicine

Phase 4

100

Beijing

2025-12-01

Active, closed

Desvenlafaxine for Preventive Treatment of Frequent Episodic Tension-type Headache

NCT07359248Tension Type Headache

DrugDesvenlafaxine

Tongji Hospital

Not applicable

432

Wuhan

2025-12-01

Not yet open

Dose-escalation of Rectal Indomethacin for Preventing PEP

NCT07247682Post-ERCP Pancreatitis

The First Affiliated Hospital of Anhui Medical University

Phase 4

1,036

Hefei

2025-12-01

Recruiting

A Study on Integrated Chinese and Western Medicine for Severe Pneumonia Caused by Multidrug-Resistant Gram-Negative Bacterial Infections

NCT07206745Severe Pneumonia Caused by Multidrug-resistant Gram-negative Bacterial Infection

Henan University of Traditional Chinese Medicine

Not applicable

152

Zhengzhou

2025-12-01

Recruiting

Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term Progression

NCT07670026Glioblastoma

DrugsTemozolomide·Sintilimab·Bevacizumab

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

Hangzhou

2025-12-01

Recruiting

Clinical Study on the Safety and Efficacy of Temporal Interference Stimulation in the Treatment of Post-Stroke Aphasia

NCT07346378Post-stroke Aphasia

The First Affiliated Hospital of Anhui Medical University

Not applicable

Hefei

2025-12-01

Active, closed

Neuromuscular Rehab for ACL Reconstruction: Knee Function & Brain Plasticity

NCT07243860Anterior Cruciate Ligament Injuries

Peking University Third Hospital

Not applicable

Beijing

2025-12-01

Recruiting

Prophylactic PS Placement to Prevent Pancreatitis After Endoscopic Transpapillary GPC for Cholelithiasis With Concomitant Choledocholithiasis

NCT07495111Cholelithiasis Associated With Common Bile Duct Stones

Qilu Hospital of Shandong University

Not applicable

Jinan

2025-12-01

Recruiting

A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma

NCT07306299Glioma, High Grade

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 1

Hangzhou

2025-12-01

Recruiting

Human Sinonasal Mucosa Heterogeneity Study

NCT07692243Human Sinonasal Mucosal Spatial Atlas

First Affiliated Hospital, Sun Yat-Sen University

Observational

100

Guangzhou

2025-12-01

Recruiting

A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer

NCT07347951Locally Advanced Rectal Cancer (LARC)

First Affiliated Hospital of Wenzhou Medical University

Phase 2

Wenzhou

2025-12-01

Recruiting

Clinical Translation Research on a Multi-omics Breast Cancer Distant Metastasis Prediction Model Empowered by Artificial Intelligence

NCT07252986Breast, Breast Cancer, Pathology

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

2,000

Hangzhou

2025-12-01

Active, closed

Phase 4 Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Chinese Participants With Generalized Myasthenia Gravis

NCT07246564Myasthenia Gravis

DrugRozanolixizumab

UCB Biopharma SRL

Phase 4

Beijing, Changchun, Changsha, Fuzhou, Guangzhou, Jinan, Shanghai, Shenzhen

2025-12-01

Recruiting

A Study of CS0159 in Patients With PBC With Inadequate Response or Intolerance to UDCA

NCT07282353Primary Biliary Cholangitis

DrugPleacbo

Cascade Pharmaceuticals, Inc

Phase 3

135

Hefei, Beijing, Chongqing, Fuzhou, Xiamen, Shenzhen, Zhanjiang, Nanning

2025-12-01

Active, closed

AI Chatbots for Anxiety Mental Health Literacy

NCT07316374Anxiety Literacy, Anxiety Disorders, Mental Health Literacy

Peking University

Not applicable

200

Beijing

2025-12-01

Recruiting

Phase II Study of Weekly Paclitaxel/Nab-Paclitaxel, Pembrolizumab, and Mirabegron for Recurrent Ovarian Cancer

NCT07261683Ovarian Cancer, Immunotherapy, Pembrolizumab

Obstetrics & Gynecology Hospital of Fudan University

Phase 2

Shanghai

2025-12

Not yet open

Sac-TMT Plus Bevacizumab as Second-Line Treatment for Advanced Non-Squamous Non-Small Cell Lung Cancer

NCT07244926Lung Cancer

DrugsSacituzumab tirumotecan·Bevacizumab

Tianjin Medical University Cancer Institute and Hospital

Phase 2

Tianjin

2025-12

Not yet open

Application of Quantum Detection-Driven Artificial Intelligence Algorithms for Single-Molecule cfDNA Characterization in the Early Diagnosis of Prostate Cancer

NCT07238959Benign Prostate Hypertrophy(BPH), Prostate Cancer (Diagnosis), Prostate Neoplasm

Shanghai Changzheng Hospital

Observational

1,100

Beijing, Guangzhou, Nanjing, Suzhou, Shanghai, Chengdu, Ningbo

2025-12

Recruiting

TCR-engineered T Cells (NW-101C) in Patients With Solid Malignant Tumors

NCT07266298Solid Metastatic Tumor

Neowise Biotechnology

Phase 1

Beijing

2025-12

Not yet open

A Clinical Trial of AK152 in Healthy Volunteers and Patients With Alzheimer' s Disease

NCT07301502Alzheimer' s Disease

Akeso

Phase 1

108

Hefei

2025-12

Recruiting

Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Pain Management in Abdominal Surgery

NCT07311369Moderate to Severe Acute Postoperative Pain

DrugHL-1186

Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.

Phase 2

Changsha

2025-12

Not yet open

Prospective Cohort Study of Neuromyelitis Optica Spectrum Disorders (NMOSD)

NCT07266051NMOSD

Xiamen Hospital of Traditional Chinese Medicine

Observational

4,000

Xiamen

2025-12

Not yet open

Effects of Compound Ejiao Syrup on Exercise Tolerance and Quality of Life in Critically Ill Patients After ICU Discharge: A Double-Blind, Multicenter,Randomized Controlled Clinical Study

NCT07157748Critically Ill Patients

Third Military Medical University

Not applicable

178

Chongqing

2025-12

Not yet open

Sedation of Remazolam Combined With Afentanil in Non-intubated Thoracoscopic Pulmonary Surgery

NCT06810843Pulmonary Nodule Cm

DrugPropofol

Qianfoshan Hospital

Not applicable

390

Jinan

2025-12

Not yet open

A First-in-Human Safety and Pharmacokinetic Trial of GenSci142 Administered as Single Ascending Doses in Healthy Chinese Women

NCT07302035Bacterial Vaginosis

DrugGenSci142

Changchun GeneScience Pharmaceutical Co., Ltd.

Phase 1

Shanghai

2025-12

Recruiting

A Long-term Safety and Efficacy Study Evaluating CM512 in Atopic Dermatitis.

NCT07230483Atopic Dermatitis (AD)

DrugCM512

Keymed Biosciences Co.Ltd

Phase 2

246

Beijing

2025-12

Not yet open

A Multicenter Study on the Normal Reference Range and Clinical Significance of the Right Atrioventricular Coupling Index Assessed by Artificial Intelligence-Based Three-Dimensional Echocardiography

NCT07292896Healthy Adults, Pulmonary Hypertension, Tricuspid Regurgitation, Heart Failure

First Hospital of China Medical University

Observational

2,640

Chongqing, Shenzhen, Shijiazhuang, Harbin, Zhengzhou, Wuhan, Xiangyang, Changchun

2025-12

Not yet open

A Phase 2 Study of BB102 in Patients With Hepatocellular Carcinoma

NCT07239986Hepatocellular Carcinoma (HCC)

DrugBB102

Broadenbio Ltd., Co.

Phase 2

Hefei, Shanghai

2025-12

Not yet open

Proprioceptive Training for Gait and Knee Function After Anterior Cruciate Ligament Reconstruction

NCT07268651Anterior Cruciate Ligament Reconstruction

Universiti Sains Malaysia

Not applicable

Leshan

2025-12

Not yet open

Combined Chemo-immunotherapy Plus SBRT in Neoadjuvant Treatment for Luminal Subtype Breast Cancer

NCT07254858HR+/HER2- Breast Cancer

First Affiliated Hospital of Wenzhou Medical University

Phase 2

302

Wenzhou

2025-12

By invitation

Efficacy of Three Gingival Displacement Methods

NCT07282977Tooth Defect, Teeth Restoration

Henan Provincial People's Hospital

Not applicable

Zhengzhou

2025-12

Not yet open

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TQB3217 Tablets in Subjects With Advanced Malignant Tumors

NCT07291050Advanced Cancer

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 1

Beijing

2025-12

Recruiting

A Multicenter Study of CAR-T Cells in Primary Ph+All

NCT07252336ALL

Zhejiang University

Phase 2

Hangzhou

2025-11-30

Recruiting

CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT

NCT07441291B ALL, Allogenetic Hematopoietic Stem Cell Transplantation, MRD-positive

DrugCar-T

Peking University People's Hospital

Phase 3

Beijing

2025-11-30

Recruiting

Efficacy of an AI System in Training Endoscopists to Assess Gastric Intestinal Metaplasia Via the EGGIM Score

NCT07208864Gastric Intestinal Metaplasia

Qilu Hospital of Shandong University

Not applicable

Jinan

2025-11-30

Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

NCT07218146Small-cell Lung Cancer

DrugZL-1310

Zai Lab (Shanghai) Co., Ltd.

Phase 3

480

Hefei, Fuzhou, Xiamen, Guangzhou, Naning, Heilongjiang, Shijiazhuang, Zhengzhou

2025-11-30

Not yet open

Rehabilitation Exercise Intervention for Rheumatoid Arthritis Patients Using Artificial Intelligence-Based Exercise Prescription System

NCT07246811Rheumatoid Arthritis (RA)

Peking University Third Hospital

Not applicable

147

Beijing

2025-11-30

Recruiting

SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC

NCT07474103Rectal Cancer, Adenocarcinoma

DrugsNal-IRI·Liposomal Irinotecan·Xeloda·Sintilimab

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Not applicable

Wuhan

2025-11-30

Recruiting

Pirtobrutinib, Lisaftoclax, and Rituximab in the Treatment of R/R DLBCL

NCT07255963DLBCL - Diffuse Large B Cell Lymphoma

DrugsPirtobrutinib·Lisaftoclax·Rituximab

The First Affiliated Hospital of Soochow University

Phase 2

Suzhou

2025-11-30

Recruiting

The Safety and Efficacy of NouvSoma001 in Ischemic Stroke

NCT06612710Ischemic Stroke

Wei Wang

Phase 1

Wuhan

2025-11-30

Recruiting

Phase III Clinical Trial of rhTNK-tPA in Treating Acute Ischemic Stroke With Extended Time Window.

NCT07201688Acute Ischemic Stroke

DrugRhTNK-tPA

CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd.

Phase 3

890

Puyang

2025-11-30

By invitation

Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation for Peripheral Facial PalsyStimulation in the Treatment of Peripheral Facial Palsy

NCT07327710Peripheral Facial Palsy, Pulsed Radiofrequency, Brain-Computer Interface, Transcranial Direct Current Stimulation

Nanjing Medical University

Not applicable

Changzhou

2025-11-30

Active, closed

A Comparative Study of the Efficacy and Safety of Telitacicept and Belimumab in the Treatment of Systemic Lupus Erythematosus Involving Multiple Units, Based on Previous Data.

NCT07053137Systemic Lupus Erythematosus, Telitacicept, Belimumab, Efficacy and Safety

Yipeng Liu

Observational

180

Jinan

2025-11-30

Recruiting

The Physiological Effect of RCexp on Ventilation/Perfusion Distribution

NCT06919484Acute Respiratory Distress Syndrome, Mechanical Ventilation

Southeast University, China

Observational

Nanjing

2025-11-30

Not yet open

Transcranial Alternating Current Stimulation for Patients With Mild Alzheimer's Disease II (TRANSFORM-AD II)

NCT07230158Alzheimer Disease

Xuanwu Hospital, Beijing

Not applicable

160

Beijing

2025-11-30

Not yet open

Ganagliflozin on the Progression of Kidney Disease in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

NCT07116928T2DM (Type 2 Diabetes Mellitus), CKD - Chronic Kidney Disease

DrugGanagliflozin

Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.

Phase 4

1,244

Shanghai

2025-11-30

Recruiting

IL-5 CAR-T Cell Therapy for Refractory/Relapsed Eosinophilic Leukemia

NCT07257640Hematologic Diseases, Neoplasms

Zhejiang University

Phase 1

Hangzhou

2025-11-30

Recruiting

Robot-Assisted vs Manual Transradial Cerebral Angiography

NCT07696936Angiography, Digital Subtraction, Robot-assisted Therapy

The First Hospital of Hebei Medical University

Not applicable

156

Shijiazhuang

2025-11-30

Not yet open

CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer

NCT07268794Metastatic Prostate Cancer, Prostate Cancer (Adenocarcinoma), Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

DrugDocetaxel

Fudan University

Phase 2

112

Shanghai

2025-11-30

Recruiting

Observational RegIstry of Effectiveness and Safety of teNecTeplase in reAl worLd Settings in China

NCT07271342Stroke

DrugTenecteplase

Beijing Tiantan Hospital

Observational

10,000

Beijing

2025-11-30

Recruiting

Effect of Perioperative High-dose Transdermal Nicotine Patch on Pain Sensitivity Among Male Abstinent Tobacco Smokers Undergoing Thoracic Surgery: A Randomized Controlled Pilot Study

NCT07250230Nicotine Dependence, Thoracic Diseases, Analgesia

DrugNicotine

Henan Provincial People's Hospital

Not applicable

Zhengzhou

2025-11-30

Not yet open

Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer

NCT06177522Pancreatic Cancer, Neoadjuvant Therapy

DrugsAlbumin-Bound Paclitaxel·Adebrelimab·Gemcitabine

Jinling Hospital, China

Phase 2

Nanjing

2025-11-30

Not yet open

A Clinical Study to Explore CT1195E in Patients With Relapsed/Refractory B-Cell Neoplasms

NCT07234045Relapsed/Refractory B-cell Non-Hodgkin Lymphoma, Relapsed/Refractory B-cell ALL

Institute of Hematology & Blood Diseases Hospital, China

Phase 1

Tianjin

2025-11-30

Recruiting

Electroacupuncture Combined With PD-1 Inhibitor for ECOG2 Advanced NSCLC

NCT07239661Non-Small Cell Lung Cancer, Electroacupuncture, PD-1 Inhibitors, ECOG PS 2 Points

Kong Fanming

Not applicable

120

Tianjin

2025-11-30

Recruiting

Safety Trial of 68Ga/177Lu-NRT6020 in FAP-Positive Advanced Solid Tumor Patients

NCT06911489Solid Tumor Malignancy

DrugPCV20

Chengdu New Radiomedicine Technology Co. LTD.

Phase 1

132

Shanghai, Tianjin

2025-11-29

Recruiting

A Phase Ⅱa Clinical Study of CL-197 Capsules

NCT07308782HIV-1 Infection

Henan Genuine Biotech Co., Ltd.

Phase 2

Beijing

2025-11-29

Recruiting

Multicenter, Single-Arm Exploratory Phase I Clinical Study (Assessment of Safety and Efficacy) of Fully Human BAFF-R Chimeric Antigen Receptor T-Cell Injection in Relapsed/Refractory BAFF-R-Positive B-Cell Lymphoma

NCT07259070DLBCL, CLL, FL, MCL

Institute of Hematology & Blood Diseases Hospital, China

Phase 1/2

Tianjin

2025-11-29

Recruiting

Spectral Precise Image Study for Brain Tumors

NCT07620470Brain Tumors

Philips Clinical & Medical Affairs Global

Observational

120

Wuhan

2025-11-28

Recruiting

Feasibility Study of Diaphragm Synchronized Pacing (DSP) Via the Left Inferior Phrenic Vein (LIPV) Approach

NCT07392749Heart Failure

RenJi Hospital

Not applicable

Shanghai

2025-11-28

Recruiting

Study of GI001 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic Leukemia

NCT07862010B-Cell Non-Hodgkin Lymphoma, B-Cell Acute Lymphoblastic Leukemia

Hematology department of the 920th hospital

Early Phase 1

Yunnan

2025-11-28

Recruiting

Intraperitoneal Injection of Liposomal Irinotecan as Monotherapy or in Combination With Recombinant Mutant Human Tumor Necrosis Factor or Bevacizumab for the Treatment of Malignant Ascites Following Failure of Prior Standard Therapy

NCT07397819Malignant Ascites

DrugsRmhTNF-NC·Liposomal Irinotecan·Bevacizumab

Dong sheng Zhang

Phase 1/2

Guangzhou

2025-11-28

Recruiting

The Prevalence of COPD in Patients With Cardiovascular Disease and the Benefit of Cardiopulmonary Co-management

NCT06909773Cardiovascular Diseases

AstraZeneca

Not applicable

3,000

Anqing, Beijing, Changsha, Chaohu, Chengdu, Chifeng, Chongqing, Dalian

2025-11-28

Active, closed

A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment

NCT07220538Ischemic Stroke Hospitalized, Impairment, Cognitive

Dr. Willmar Schwabe GmbH & Co. KG

Phase 4

400

Anyang, Baotou, Beijing, Benxi, Chenzhou, Chifeng, Dalian, Harbin

2025-11-28

Recruiting

Suraxavir Marboxil And Oseltamivir for Influenza Prophylaxis Under a Hospital-based Setting

NCT07236814Influenza

DrugOseltamivir

Capital Medical University

Phase 3

384

Beijing

2025-11-28

Recruiting

Study of Food Effects of VV119 Capsules in Chinese Healthy Volunteers

NCT07240636Healthy Volunteers

DrugVV119

Vigonvita Life Sciences

Phase 1

Hefei

2025-11-28

Recruiting

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

NCT07169851Nausea, Vomiting, Drug-Related Side Effects and Adverse Reactions, Neoplasms

Eli Lilly and Company

Phase 2

204

Changde, Guangzhou, Hangzhou, Jiangmen, Luoyang

2025-11-28

Recruiting

Study of CM512 Injection in Subjects With Chronic Spontaneous Urticaria(CSU)

NCT07166211Chronic Spontaneous Urticaria (CSU)

DrugCM512

Keymed Biosciences Co.Ltd

Phase 2

Tianjin

2025-11-27

Recruiting

A Study of Rocbrutinib in Participants With Relapse or Refractory Non-GCB Diffuse Large B-Cell Lymphoma

NCT07189065Diffuse Large B-Cell Lymphoma (DLBCL)

DrugsRocbrutinib·Bendamustine·Lenalidomide·Rituximab

Guangzhou Lupeng Pharmaceutical Company LTD.

Phase 2

150

Hefei, Beijing, Chongqing, Fuzhou, Guangzhou, Meizhou, Nanning, Shijiazhuang

2025-11-27

Recruiting

A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC)

NCT07108270Neoplasms, Endometrial

DrugsDostarlimab·Paclitaxel·Carboplatin

GlaxoSmithKline

Phase 2

Jinan

2025-11-27

Recruiting

Study of the Efficacy and Safety of ICP-332 in Participants With Prurigo Nodularis

NCT07236099Prurigo Nodularis (PN)

Beijing InnoCare Pharma Tech Co., Ltd.

Phase 2

135

Wuhu, Beijing, Chongqing, Fuzhou, Guangzhou, Shijiazhuang, Jingzhou, Changsha

2025-11-27

Active, closed

Parent-administered Pediatric Tuina Versus Routine Care for Pediatric Functional Dyspepsia

NCT07369687Pediatric Functional Dyspepsia

The Hong Kong Polytechnic University

Not applicable

Hong Kong

2025-11-27

Recruiting

A Prediction Model in Pregnant Women With Aplastic Anemia

NCT07101770Aplastic Anemia, Pregnancy, Prediction Model

Peking University People's Hospital

Observational

300

Beijing

2025-11-27

Recruiting

YSCH-01 Via Nebulization in Pulmonary Metastasis of Advanced Solid Tumors and Non-small Cell Lung Cancer (NSCLC)

NCT07793500NSCLC, Advanced Solid Tumor

DrugYSCH-01

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Early Phase 1

Beijing

2025-11-27

Recruiting

A Phase Ⅰ/Ⅱa Clinical Study of GEN-725 in Combination With Dositinib

NCT07362940Non-Small Cell Lung Cancer

DrugsDositinib mesylate·GEN-725

Henan Genuine Biotech Co., Ltd.

Phase 1/2

110

Beijing, Changsha, Jinan, Xiamen, Zhengzhou

2025-11-27

Recruiting

A Study of MHB042C in Patients With Advanced Solid Tumors

NCT07192107Advanced Malignant Solid Tumor

Minghui Pharmaceutical (Hangzhou) Ltd

Phase 1/2

200

Guangzhou

2025-11-27

Recruiting

Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN

NCT06994845Primary Immunoglobulin A Nephropathy (IgAN)

DrugIptacopan

Novartis Pharmaceuticals

Phase 3

Hangzhou, Beijing

2025-11-27

Recruiting

FL-261 Imaging for Cancer Diagnosis and Staging

NCT07510321Non-Small Cell Lung Cancer, Colorectal Cancer, Head & Neck Cancer, Advanced Solid Tumors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Observational

Wuhan

2025-11-27

Recruiting

Single-dose,First-in-human of KLA478

NCT07240675Healthy Volunteers

Hunan Kelun Pharmaceutical Co., Ltd.

Phase 1

Shanghai

2025-11-26

Active, closed

Safety and Efficacy of Tarperprumig in Adult Participants With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis

NCT07160608Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Alexion Pharmaceuticals, Inc.

Phase 2

Beijing, Guangzhou, Hangzhou, Nanchang

2025-11-26

Recruiting

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

NCT07227402Renal Cell Carcinoma

DrugsZanzalintinib·Belzutifan·Cabozantinib

Merck Sharp & Dohme LLC

Phase 3

904

2025-11-26

Recruiting

Establishment of a Multimodal Standard Database for Inflammation-related Ophthalmopathy

NCT07628946Ocular Surface Disease, Inflammatory Disease, Retinal Disease, Choroid Diseases

Dan Chen

Observational

3,000

Beijing

2025-11-26

Recruiting

A Phase II Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of SR604 Injection in Patients With Von Willebrand Disease

NCT07640893Von Willebrand Disease (VWD)

DrugSR604

Shanghai RAAS Blood Products Co., Ltd.

Phase 2

Changsha, Hefei, Jinan, Nanning, Suzhou, Taiyuan, Tangshan, Tianjin

2025-11-26

Recruiting

A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

NCT07217301IO Resistant Squamous and Nonsquamous NSCLC

Takeda

Phase 3

1,200

Hefei, Beijing, Chongqing, Fuzhou, Guangzhou, Shijiazhuang, Harbin, Xinxiang

2025-11-26

Recruiting

Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial

NCT07279077Colon Cancer, Neoadjuvant Therapies, Immune Checkpoint Therapy, Radiation Therapy

Sixth Affiliated Hospital, Sun Yat-sen University

Phase 2

Guangzhou

2025-11-26

Recruiting

Application of Orelabrutinib With or Without CD20 Monoclonal Antibody in Previously Untreated Marginal Zone Lymphoma

NCT07355699Marginal Zone Lymphoma(MZL)

DrugsOrelabrutinib·Obinutuzumab·Rituximab

Beijing Tongren Hospital

Phase 4

Beijing

2025-11-25

Recruiting

Clinical Trial of PCV24 in Infants and Children Aged 2 Months to 5 Years

NCT07300644Pneumococcal Infectious Disease

DrugsSinovac PCV24·Prevnar

Sinovac Life Sciences Co., Ltd.

Phase 2

420

Huanggang, Xiangyang, Xianning

2025-11-25

By invitation

Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT07256392Chronic Spontaneous Urticaria

DrugBarzolvolimab

Celldex Therapeutics

Phase 3

1,370

2025-11-25

Recruiting

Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Docetaxel Plus Cyclophosphamide

NCT07537699Nausea and Vomiting Caused by Chemotherapy

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

Hangzhou

2025-11-25

Recruiting

Targeted Induction Therapy for Stage III Unresectable EGFR Mutant Positive NSCLC

NCT07742332EGFR, NSCLC (Non-small Cell Lung Cancer), Locally Advanced Non-Small Cell Lung Cancer, Radiotherapy

Peng Zhang

Phase 2

160

Shanghai

2025-11-25

Recruiting

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

NCT07155174Small Cell Lung Cancer

DrugsABBV-706·Lurbinectedin·Etoposide·Atezolizumab

AbbVie

Phase 2

180

Beijing, Zhengzhou, Wuhan, Nanchang, Shanghai, Chengdu

2025-11-25

Active, closed

A Phase 3 Study of VVN461 Ophthalmic Solution for Noninfectious Anterior Uveitis

NCT07136805Non-infectious Anterior Uveitis

DrugPrednisolone acetate

VivaVision Biotech, Inc

Phase 3

154

Chongqing, Beijing

2025-11-25

Active, closed

Effect of Perception-based Interventions on Public Acceptance of Using Large Language Models in Medicine

NCT07304908Large Language Models, Acceptability of Health Care, Perception, Self

Peking University

Not applicable

3,000

Beijing

2025-11-25

Recruiting

A Phase II Study To Evaluate the Efficacy And Safety Of HRS-1301 In Participants With Dyslipidemia

NCT07229937Hyperlipidemia

Shandong Suncadia Medicine Co., Ltd.

Phase 2

189

Harbin

2025-11-25

Recruiting

Phase I Clinical Study To Evaluate Pharmacokinetic Profile, Safety, Efficacy and Immunogenicity Of Ipilimumab Biosimilar HLX13 Vs. YERVOY® (US-Sourced YERVOY®) As A First-Line Treatment For Patients With Unresectable Hepatocellular Carcinoma

NCT07176650Hepatocellular Carcinoma (HCC)

DrugsYervoy·Opdivo

Shanghai Henlius Biotech

Phase 1

246

Beijing, Bengbu, Changchun, Changsha, Chengdu, Dongguan, Fuzhou, Ganzhou

2025-11-25

Recruiting

Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study

NCT07247968Esketamine, ECT, Depression, Adolescent

Min Su

Early Phase 1

220

Chongqing

2025-11-25

Recruiting

A Phase I Study of WTX212A Monotherapy or in Combination With Radiotherapy in Patients With Advanced Solid Tumors

NCT07269899Solid Tumor Cancer, Cancer

Sun Yat-sen University

Phase 1

Guangzhou

2025-11-25

Not yet open

Efficacy and Safety of Stapokibart in Non-Allergic Rhinitis With Eosinophilia Syndrome

NCT07240376Non-Allergic Rhinitis With Eosinophilia Syndrome

DrugStapokibart

Huazhong University of Science and Technology

Not applicable

Guangzhou, Wuhan, Xiangyang, Nanchang, Chengdu, Beijing, Shanghai

2025-11-25

Recruiting

Safety and Efficacy of Anricfen for Postoperative Analgesia and Rehabilitation Promotion After Pancreaticoduodenectomy.Intervention Measures: For Normal Adults, Administer Ariceptin Injection Intravenously Post-operation at a Dose of 1 μg/Kgevery 8 Hours for Three Consecutive Days After Surgery.

NCT07514637Patients Who Undergo Pancreaticoduodenectomy

DrugAnrikefon

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 2

Nanjing

2025-11-25

Recruiting

Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Trastuzumab Deruxtecan

NCT07537673Nausea and Vomiting Caused by Trastuzumab Deruxtecan

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

Hangzhou

2025-11-25

Recruiting

Nephron-sparing Treatment of Tislelizumab + Nab-Paclitaxel for Renal Pelvic Cancer

NCT07233252Renal Pelvic Carcinoma, Tislelizumab, PD-1 Inhibitor, Kidney-sparing

DrugsNab-paclitaxel·Tislelizumab

Tianjin Medical University Second Hospital

Phase 2

Tianjin

2025-11-25

Recruiting

Local Methylene Blue Injection for Prevention of Anastomotic Leakage and Permanent Stoma After Low Anterior Resection for Rectal Cancer

NCT07833319Rectal Cancers

DrugMethylene Blue

Peking University Cancer Hospital & Institute

Phase 2

Beijing

2025-11-25

Recruiting

SA1211 Injection Phase 1 Study

NCT07275918Chronic Hepatitis B

Suzhou Siran Biotechnology Co.,Ltd.

Phase 1

Changchun

2025-11-25

Recruiting

Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Gemcitabine Plus Paclitaxel

NCT07537660Nausea and Vomiting Caused by Chemotherapy

Second Affiliated Hospital, Zhejiang University, School of Medicine

Phase 2

Hangzhou

2025-11-25

By invitation

Concept-verification Clinical Trial on the Inhibition of Breast Cancer Lung Metastasis Progression by Hyperbaric Oxygen

NCT07514728Breast Cancer, Lung Metastasis, Hyperbaric Oxygen Therapy

Jinan Central Hospital

Not applicable

Jinan

2025-11-24

Recruiting

JN002 for the Treatment of Dry Eye Disease

NCT07245017Dry Eye

Eye & ENT Hospital of Fudan University

Early Phase 1

Shanghai

2025-11-24

Recruiting

A Phase Ia Clinical Trial of HW241045

NCT07448194Healthy Volunteers, IPF

Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.

Phase 1

Beijing

2025-11-24

Recruiting

A Phase II Clinical Study Evaluating Entinostat With or Without Anlotinib + Fulvestrant for the Treatment of Hormone Receptor (HR) -Positive, Human Epidermal Growth Factor Receptor-2 (HER-2) -Negative Advanced Breast Cancer That Relapsed or Progressed After Endocrine Therapy

NCT07330544Breast Cancer

DrugsEntinostat·Anlotinib·Fulvestrant

Zhejiang Cancer Hospital

Phase 2

118

Zhejiang

2025-11-24

Recruiting

Comparison of the Efficacy and Safety of Ciprofol Versus Propofol for Sedation in ICU Patients Undergoing Non-Invasive Ventilation

NCT07536750Respiratory Failure, Critical Illness

Nanfang Hospital, Southern Medical University

Observational

1,680

Guangzhou

2025-11-24

Recruiting

Specialist Nurse-Led Nursing Management for Patients Undergoing Head and Neck Cancer Surgery

NCT07622381Head & Neck Cancer

Tianjin Medical University Cancer Institute and Hospital

Not applicable

Tianjin

2025-11-24

Not yet open

A Study of Tumor-Agnostic MRD Detection in Stage III Colorectal Cancer

NCT07254156Colorectal Cancer, MRD, ctDNA

Sun Yat-sen University

Observational

229

Guangzhou

2025-11-24

Not yet open

Subthalamic Nucleus Versus Globus Pallidal Internus Deep Brain Stimulation for Parkinson Disease

NCT07250685PD - Parkinson's Disease

Zhang Jianguo

Not applicable

Beijing, Wuhan, Nanjing, Dalian, Jinan, Shanghai, Tianjin, Hangzhou

2025-11-24

Recruiting

Taurine's Therapeutic Effect on Acute Radiation-induced Oral Mucositis and Dermatitis

NCT07029178Radiation Induced Oral Mucositis, Radiodermatitis

DrugTaurine

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Phase 2

160

Shanghai

2025-11-24

Recruiting

Multi-center Randomized Controlled Clinical Study of Shenling Baishu Granule to Prevent the Recurrence of Low-risk Colorectal Adenoma

NCT06930157Low-risk Colorectal Adenoma

Shanghai Jiao Tong University School of Medicine

Phase 4

624

Shanghai

2025-11-24

Recruiting

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

NCT07286175Bipolar Disorder

DrugBrenipatide

Eli Lilly and Company

Phase 2

400

Changsha, Hangzhou, Huzhou, Jinan, Shanghai, Shijiazhuang, Tianjin, Xiamen

2025-11-24

Recruiting

Longitudinal Follow-up and Health-Related Outcomes in Liver Transplant Recipients and Living Donors

NCT07301853Living Donor Liver Transplantation Recipients, Deceased Donor Liver Transplantation Recipients, Living Liver Donor

Second Affiliated Hospital, Zhejiang University, School of Medicine

Observational

9,999

Hangzhou

2025-11-24

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Efficacy of BC2027 in Patients With Advanced Solid Malignancies

NCT07368478Advanced Solid Malignancies

Biocity Biopharmaceutics Co., Ltd.

Phase 1

180

Shanghai

2025-11-24

Recruiting

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

NCT07174310Parkinson's Disease

DrugPrasinezumab

Hoffmann-La Roche

Phase 3

900

Beijing, Changchun, Chengdu, Chongqing, Fuzhou, Guangzhou, Hangzhou, Nanjing

2025-11-24

Recruiting

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

NCT06996782Advanced or Metastatic Non-small Cell Lung Cancer

DrugsRamucirumab·Rilvegostomig·Nab-paclitaxel·Pemetrexed

AstraZeneca

Phase 1/2

152

Chengdu, Chongqing, Deyang, Fuzhou, Guangzhou, Jinan, Shanghai, Shenyang

2025-11-24

Recruiting

An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases

NCT07236762Systemic Lupus Erythematosus, Lupus Nephritis (LN), Sjogren's Syndrome, Inflammatory Myopathy

DrugYTS109 cell

China Immunotech (Beijing) Biotechnology Co., Ltd.

Phase 1

Bengbu

2025-11-24

Recruiting

A Study of SHR-A2102 in Combination With Other Anti-tumor Therapies for Resectable Non-small Cell Lung Cancer

NCT07229729Non-small Cell Lung Cancer

DrugsSHR-A2102·Osimertinib·Adebrelimab·Paclitaxel

Shanghai Hengrui Pharmaceutical Co., Ltd.

Phase 2

300

Guangzhou

2025-11-24

By invitation

RCT on Traditional Exercise Interventions for Physical and Mental Health in Hearing-Impaired Individuals

NCT07259694Hearing-Impaired

Northeast Normal University

Not applicable

Changchun

2025-11-24

Recruiting

A Study of Silkworm Pupa Powder Intervention in the Nutritional Status of Patients With Alzheimer's Disease.

NCT07059871AD - Alzheimer's Disease, Sarcopenia, Asthenia

Zhejiang Hospital

Not applicable

200

Hangzhou

2025-11-23

Recruiting

Closed-Loop Neurofeedback Targeting the Left Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety

NCT07244484Coronary Heart Disease (CHD), Anxiety Disorders

Shenyang Medical College

Not applicable

Shenyang

2025-11-23

Recruiting

FMS-CrossFit Training Program (FCTP) to Improve School Readiness in Preschool Children With Autism Spectrum Disorder

NCT07532395Autism Spectrum Disorder

Peking University

Not applicable

184

Beijing, Fuzhou

2025-11-22

Recruiting

A Phase II Clinical Study on the Efficacy and Safety of SHR-2173 Injection in the Treatment of Patients With Active Lupus Nephritis

NCT07229742Active Lupus Nephritis

DrugSHR-2173

Guangdong Hengrui Pharmaceutical Co., Ltd

Phase 2

Nanjing

2025-11-22

Recruiting

Intraosseous Infusion in Hematologic Critical Patients

NCT07239375Intraosseous Infusions

Shanxi Bethune Hospital

Observational

Taiyuan

2025-11-22

Recruiting

Effect of Visual-Guided Balance Training on Knee Motor Function and Biomechanical Characteristics After ACL Reconstruction

NCT07306221Anterior Cruciate Ligament Injuries

Peking University Third Hospital

Not applicable

Beijing

2025-11-22

Recruiting

Efficacy and Safety of the KPCXM18 Injection in Patients With Acute Ischemic Stroke

NCT07279493Acute Ischemic Stroke

Kunming Pharmaceuticals, Inc.

Phase 2

300

Beijing, Shenzhen, Cangzhou, Hengshui, Daqing, Anyang, Nanyang, Xuzhou

2025-11-22

Recruiting

Exploratory Clinical Study of Camrelizumab Combined With Concurrent Chemoradiotherapy as an Organ-preserving Strategy for Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

NCT07622797Late-stage Resectable Esophageal Squamous Carcinoma

DrugsAlbumin-Bound Paclitaxel /nab-Paclitaxel·Camrelizumab·Capecitabine·Carboplatin

The First Affiliated Hospital of Henan University of Science and Technology

Phase 2

164

Luoyang

2025-11-21

Recruiting

Exploratory Trial of Navigational Bronchoscopy-Guided Cryoablation in Lung Cancer Treatment

NCT07301411Lung Malignancies

Tianjin Puli Ark Medical Technology Co., Ltd.

Not applicable

Shanghai

2025-11-21

Recruiting

Iparomlimab and Tuvonralimab (QL1706) Combination With Lenvatinib as Neoadjuvant Therapy for ccRCC

NCT07389629Iparomlimab and Tuvonralimab, Clear Cell Renal Cell Carcinoma, Neoadjuvant Therapy

DrugLenvatinib

Sun Yat-sen University

Phase 2

Guangzhou

2025-11-21

Recruiting

A Platform Study of In Vivo CAR-T for Treating Advanced Malignant Tumors Based on Target Screening

NCT07395479Advanced Malignant Tumours

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Early Phase 1

Beijing

2025-11-21

Active, closed

Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)

NCT07162883Carcinoma, Non-Small-Cell Lung

DrugsKeytruda·Pembrolizumab

Qilu Pharmaceutical Co., Ltd.

Phase 3

146

Bengbu, Beijing, Chongqing, Lanzhou, Haikou, Zhengzhou, Changsha, Nanjing

2025-11-21

Recruiting

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough - China Extension

NCT07650084Refractory Chronic Cough

DrugCamlipixant

GlaxoSmithKline

Phase 3

Leshan, Beijing, Changsha, Chengdu, Chongqing, Dongguan, Ganzhou, Guangzhou

2025-11-21

By invitation

Dynamic Effects of Different Anesthetic Agents on the Immune Function of Healthy Volunteers

NCT07268872Immune System

Henan Provincial People's Hospital

Not applicable

Henan

2025-11-21

Recruiting

IASO208 Injection in the Treatment of Relapsed/Refractory B-cell Malignancies

NCT07309900Relapsed/Refractory B-cell Malignancies

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 1

Wuhan

2025-11-21

Recruiting

Asymptomatic TB With Innovative Modified Short-course Regimens

NCT06153069Tuberculosis

Huashan Hospital

Phase 4

426

Beijing, Liupanshui, Nayong, Shanghai, Hangzhou

2025-11-21

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site. Derived from ClinicalTrials.gov. Retrieved 7 November 2026. https://priyalifescience.com/clinical-trials-china?page=12

Query this register directly

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,187 studies in total at the last sync on 07 Nov 2026, 03:17 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in China?

11,790 of the 19,187 studies in this register are recruiting new participants as of the 07 Nov 2026, 03:17 UTC sync. A further 3,998 have not yet opened recruitment, 2,715 are active but closed to new participants, and 684 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (423) Advanced Solid Tumors (187) Colorectal Cancer (179) Gastric Cancer (175) Hepatocellular Carcinoma (154) Advanced Solid Tumor (153) Non-Small Cell Lung Cancer (145) Solid Tumor (142) Acute Ischemic Stroke (140) Lung Cancer (135) Non-small Cell Lung Cancer (132) Pancreatic Cancer (131) Multiple Myeloma (128) Coronary Artery Disease (122) Prostate Cancer (110)

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Browse trials by site location

Beijing (5576) Shanghai (3879) Guangzhou (3345) Hangzhou (1819) Wuhan (1343) Chengdu (1307) Nanjing (1211) Changsha (1154) Chongqing (1078) Fuzhou (1040) Tianjin (934) Zhengzhou (931) Hefei (896) Jinan (783) Changchun (639)

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.