Nicotine is named as an intervention in 3 current clinical trials in our China, Norway and Canada registers. 2 are recruiting patients now. The most common phase is Not applicable. The sponsor with the most trials is Henan Provincial People's Hospital (1). The most-studied condition is Nicotine Dependence.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Smoking Cessation and Menstrual Cycle Phase
NCT05515354 · ClinicalTrials.gov ↗ · Nicotine Dependence, Tobacco Smoking, Smoking Cessation
|
Phase 4 | Recruiting | Centre for Addiction and Mental Health | Canada |
|
Effect of Perioperative High-dose Transdermal Nicotine Patch on Pain Sensitivity Among Male Abstinent Tobacco Smokers Undergoing Thoracic Surgery: A Randomized Controlled Pilot Study
NCT07250230 · ClinicalTrials.gov ↗ · Nicotine Dependence, Thoracic Diseases, Analgesia
|
Not applicable | Recruiting | Henan Provincial People's Hospital | China |
|
Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco
NCT05290025 · ClinicalTrials.gov ↗ · Smoking Cessation, Substance-Related Disorders
|
Not applicable | Active, closed | Haukeland University Hospital | Norway |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
48 single-substance products containing Nicotine on the HPRA medicines list.
No entry for Nicotine in the EMA, FDA or German BfArM shortage lists we track.
| Lead sponsor | Trials |
|---|---|
| Henan Provincial People's Hospital | 1 |
| Haukeland University Hospital | 1 |
| Centre for Addiction and Mental Health | 1 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in China | 1 | 1 |
| Clinical trials in Norway | 1 | 0 |
| Clinical trials in Canada | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
3 current trials in our China, Norway and Canada registers name Nicotine as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 2 of the 3 trials are recruiting: 1 with sites in China and 1 with sites in Canada. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Henan Provincial People's Hospital (1), Haukeland University Hospital (1) and Centre for Addiction and Mental Health (1). The number in brackets is how many trials each organisation leads.
Yes. The HPRA medicines list includes 48 single-substance products containing Nicotine, for example NiQuitin 14 mg/24 hrs transdermal patches (Chefaro Ireland DAC,). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Not in the lists we track: Nicotine has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Nicotine works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Nicotine works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Nicotine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.