Tranexamic Acid clinical trials
Tranexamic Acid is named as an intervention in 43 current clinical trials in our Canada, China, Egypt, Israel, USA, India, Belgium, Denmark, Turkey, Mexico, Italy, Netherlands, Norway, Taiwan and Australia registers. 29 are recruiting patients now. The most common phase is Phase 4. The sponsor with the most trials is Assiut University (4). The most-studied condition is Bleeding. The EU clinical trials register (CTIS) separately lists 1 authorised or ongoing trial.
Where Tranexamic Acid is approved
All regulators →Of the three regulators tracked here, the first to approve Tranexamic Acid was the US, on 30 Dec 1986. It is approved in 2 of the 3 regulators tracked here.
- 1 EU safety letter (DHPC), latest: adverse event for Tranexamic acid, 11 Dec 2025
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
What health systems spend on Tranexamic Acid
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
How Tranexamic Acid works
All drug targets →- Plasminogen inhibitor InhibitorTarget: PLG plasminogen✓ In ChEMBL and the Guide to Pharmacology
- Gastrointestinal hemorrhagePhase 3
- HemoptysisPhase 3
- Pulmonary hemorrhagePhase 3
- SeizurePhase 3
- SepsisPhase 3
- ShockPhase 3
- ThrombocytopeniaPhase 3
- ThromboembolismPhase 3
- Von Willebrand diseasePhase 3
- AnemiaPhase 3
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL877, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 6573, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Tranexamic Acid
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 3 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Reference identifiers for Tranexamic Acid
- ATC code
- B02AA02
- ChEMBL
- CHEMBL877
- DrugBank
- DB00302
- PubChem CID
- 5526
- CAS number
- 1197-18-8
- FDA UNII
- 6T84R30KC1
- Wikidata
- Q418666
- Wikipedia
- Tranexamic acid
Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.
Trials by status
Trials by phase
Clinical trials of Tranexamic Acid
43 trialsRegisters list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Tranexamic Acid in the EU trials register (CTIS)
1 trialAuthorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Tranexamic Acid. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.
| Study | Phase | Status | Sponsor | Countries |
|---|---|---|---|---|
|
Oral versus Intravenous Tranexamic Acid for Blood Loss Prevention in Off-Pump Coronary Artery Bypass Surgery: A
Randomised Non-Inferiority Trial (TRANSCAB Study)
2026-526581-24-01 · Cardiovascular Diseases
|
Phase 4 | Authorised | Sante et Prevoyance | Belgium |
Tranexamic Acid across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
3 single-substance products containing Tranexamic Acid on the HPRA medicines list.
- Cyklokapron 100 mg/mL solution for injection/infusionPfizer Healthcare Ireland Unlimited Company · PA0822/117/001 · Marketed
- Tranexamic Acid 100 mg/ml solution for injection/infusionIbigen Srl · PA1862/002/001 · Marketed
- Tranexamic acid 100 mg/ml Solution for InjectionAccord Healthcare Ireland Ltd. · PA2315/178/001 · Not marketed
Supply shortages
No entry for Tranexamic Acid in the EMA, FDA or German BfArM shortage lists we track.
Conditions studied with Tranexamic Acid
72 conditionsAll 72 conditions
| Condition (as registered) | Trials |
|---|---|
| Bleeding | 3 |
| Cesarean Delivery | 2 |
| Blood Loss, Surgical | 2 |
| Intraoperative Blood Loss | 2 |
| Melasma | 2 |
| Postoperative Blood Loss | 1 |
| Hemorrhage Lung | 1 |
| Endobronchial Mass | 1 |
| Intracerebral Hemorrhagic Stroke | 1 |
| Chronic Subdural Hematoma | 1 |
| Total Knee Arthroplasty | 1 |
| Postpartum Hemorrhage | 1 |
| Systemic Autoimmune Diseases | 1 |
| Trauma Coagulopathy | 1 |
| Hemorrhage | 1 |
| Liver Transplantation | 1 |
| Tranexamic Acid | 1 |
| End-stage Liver Disease (ESLD) | 1 |
| Metastasis Spinal Tumor | 1 |
| Knee Osteoarthritis | 1 |
| Rotator Cuff Tear Repair | 1 |
| Osteoarthritis | 1 |
| Bariatric Surgery | 1 |
| Bariatric Patients | 1 |
| Bariatric Surgery Complications | 1 |
| Hematoma, Subdural, Chronic | 1 |
| Coronary Artery Disease | 1 |
| Perioperative Bleeding | 1 |
| ACL Reconstruction | 1 |
| Hemarthrosis | 1 |
| Melanoma | 1 |
| Surgical Complication | 1 |
| Tooth Extraction | 1 |
| Distal Radius Fractures | 1 |
| Epistaxis Nosebleed | 1 |
| Brain Tumor | 1 |
| Lactating Women on Select DOI | 1 |
| Breastfed Infants of Mothers on Select DOI | 1 |
| Hematologic Neoplasms | 1 |
| Cancer | 1 |
| Tumour | 1 |
| Surgery | 1 |
| Subdural Hematoma | 1 |
| Myelodysplastic Syndromes | 1 |
| Acute Myeloid Leukemia | 1 |
| Myelodysplastic/Myeloproliferative Neoplasm | 1 |
| Postoperative Bleeding | 1 |
| Hemorrhagic Shock | 1 |
| Trauma Injury | 1 |
| Surgery, Cardiac | 1 |
| Tranxemic Acid | 1 |
| Activated Clotting Time | 1 |
| Heparin | 1 |
| Cerebral Palsy | 1 |
| Hip Surgery Corrective | 1 |
| Tranexamic Acid Use | 1 |
| Postpartum Hemorrhage (PPH) | 1 |
| Hemostasis | 1 |
| Colon Neoplasm | 1 |
| Sepsis | 1 |
| Von Willebrand Disease (VWD) | 1 |
| Inherited Bleeding Disorders in Children | 1 |
| Pediatric Hemostatic Disorders | 1 |
| Pediatric | 1 |
| Orthopedic Disorder | 1 |
| Melasma (Facial Melasma) | 1 |
| Facial Melasma | 1 |
| Striae Rubra | 1 |
| Female | 1 |
| With | 1 |
| Facial | 1 |
| Blood Loss | 1 |
Sponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Assiut University | 4 |
| St. Olavs Hospital | 2 |
| RenJi Hospital | 2 |
| Second Affiliated Hospital, Zhejiang University, School of Medicine | 2 |
| Hua Luo | 2 |
| Sohag University | 2 |
| Ascension Health | 1 |
| Youssef Yammine | 1 |
| Christian Medical College and Hospital, Ludhiana, India | 1 |
| ScinnoHub Pharmaceutical Co., Ltd | 1 |
| The Second Affiliated Hospital of Kunming Medical University | 1 |
| Santa Maria Hospital - GVM Care & Research | 1 |
| Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 1 |
| Clinique Saint-Luc | 1 |
| Chirec | 1 |
+ 20 more sponsors in the trial list above.
By country register
A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.
Related compounds
Questions about Tranexamic Acid trials
How many clinical trials are testing Tranexamic Acid?
43 current trials in our Canada, China, Egypt, Israel, USA, India, Belgium, Denmark, Turkey, Mexico, Italy, Netherlands, Norway, Taiwan and Australia registers name Tranexamic Acid as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.
Are Tranexamic Acid trials recruiting patients?
Yes. 29 of the 43 trials are recruiting: 8 with sites in Canada, 5 with sites in China, 4 with sites in Egypt, 3 with sites in Israel, 1 with sites in USA, 2 with sites in India, 2 with sites in Denmark, 1 with sites in Turkey, 2 with sites in Mexico, 1 with sites in Netherlands, 1 with sites in Norway and 1 with sites in Taiwan. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Tranexamic Acid clinical trials?
Assiut University (4), St. Olavs Hospital (2), RenJi Hospital (2) and Second Affiliated Hospital, Zhejiang University, School of Medicine (2), among 35 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Is Tranexamic Acid licensed in Ireland?
Yes. The HPRA medicines list includes 3 single-substance products containing Tranexamic Acid, for example Cyklokapron 100 mg/mL solution for injection/infusion (Pfizer Healthcare Ireland Unlimited Company). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Tranexamic Acid shortage?
Not in the lists we track: Tranexamic Acid has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Tranexamic Acid works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Tranexamic Acid works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Tranexamic Acid (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.