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Trackers› Clinical trials› Nevada
Clinical trial register · United States · industry-sponsored

Clinical Trials in Nevada, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9118 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 06 Oct 2026, 03:16 UTC
9118
Studies in scope
industry-sponsored, all four open statuses
4945
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 5290 Florida 4430 Illinois 2481 Georgia 2368 Arizona 2238
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AbbVie11 AstraZeneca11 Merck Sharp & Dohme LLC10 Hoffmann-La Roche8 Eli Lilly and Company7
State
California5290 Florida4430 Illinois2481 Georgia2368 Arizona2238
All 51 states
Target enrolment
to

Trials with a site in Nevada

295 of 9118 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Not yet open
Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial Cancer
NCT07578649Endometrial Neoplasms, Endometrial Cancer
DrugsPF-08634404·Keytruda·Pembrolizumab
Pfizer
Phase 3
600
Florida, Minnesota, Nevada, Ohio, Oregon, Tennessee, Texas, Virginia
2026-10-09
Recruiting
A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)
NCT07541170Non-small Cell Lung Cancer
DrugsDivarasib·Opdivo·Nivolumab·Keytruda
Hoffmann-La Roche
Phase 3
400
California, Georgia, Michigan, Nevada, New Mexico
2026-09-30
Recruiting
A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
NCT07029945Geographic Atrophy
Biojiva LLC
Phase 1/2
152
Arizona, Mississippi, Nevada, Ohio, Texas, Utah, Washington
2026-09-29
Recruiting
A Study to Test the Effects of Centanafadine in Adults With Attention-deficit/Hyperactivity Disorder and Emotional Dysregulation
NCT07759154Attention-deficit/Hyperactivity Disorder, Emotional Dysregulation
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
80
Florida, Louisiana, Massachusetts, Missouri, Nevada, New Jersey, New York, Ohio
2026-09-01
Recruiting
A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)
NCT07645248Asthma
GlaxoSmithKline
Phase 3
110
Florida, Kentucky, Missouri, Nevada, Oregon, South Carolina, Texas
2026-09-01
Recruiting
Brexanolone Lifting Outcomes Of Moms
NCT07822321Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression
Lipocine Inc.
Phase 3
120
Arizona, California, Colorado, Georgia, Idaho, Illinois, Louisiana, Nevada
2026-09
Recruiting
A Clinical Trial to Evaluate the Effects of an Omega-3-containing Supplement on DHA and EPA Levels in the Blood
NCT07753174Omega-3 Deficiency, DHA and EPA Blood Levels, Cardiovascular Health, Cognitive Health
Revive Active
Not applicable
49
Nevada
2026-09
Recruiting
A Clinical Trial to Evaluate the Effects of a Powder Supplement in Supporting Lean Muscle Development, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, and Overall Wellness
NCT07766395Lean Muscle Development, Muscular Endurance, Hormone-Related Wellness, Digestive Comfort
Clean Nutraceuticals
Not applicable
35
Nevada
2026-09
Recruiting
Efficacy, Safety, and Tolerability of Encaleret in Participants With Chronic Hypoparathyroidism
NCT07805356Hypoparathyroidism, Chronic Hypoparathyroidism
DrugEncaleret
Calcilytix Therapeutics, Inc., a BridgeBio company
Phase 3
160
Nevada, North Carolina, Texas
2026-08-31
Recruiting
A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism
NCT07699471Hypoparathyroidism
MBX Biosciences
Phase 3
160
Florida, Louisiana, Nevada, New York, North Carolina, South Carolina, Texas, Washington
2026-08-26
Recruiting
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
NCT07776509Obesity or Overweight, Weight-Related Comorbidity, With/Without Diabetes Mellitus, Type 2
DrugLenbelintide
AstraZeneca
Phase 3
500
California, Florida, Georgia, Illinois, Maryland, Missouri, Nevada, New Jersey
2026-08-24
Recruiting
RELIEVE Study: NT 201 Intravesical Administration Using Vibe System (ViXe Combination Product) for the Treatment of Idiopathic Overactive Bladder
NCT07553065Overactive Bladder (OAB)
Vensica Therapeutics Ltd.
Phase 2
210
Nevada
2026-08-14
Recruiting
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
NCT07770841Overweight, Obesity
DrugSemaglutide
Novo Nordisk A/S
Phase 3
450
Alabama, California, Florida, Hawaii, Kentucky, Missouri, Nevada, Oregon
2026-08-12
Recruiting
A Study to Assess the Skin Irritation and Sensitization of Estradiol/Levonorgestrel TDS in Healthy Postmenopausal Subjects
NCT07794150Menopause, Healthy Female Participants
Corium Innovations, Inc.
Phase 1
250
Nevada
2026-08-10
Recruiting
A Phase 1 Trial of AMG 691 in Healthy Chinese and Japanese Volunteers
NCT07745907Healthy Participants
DrugAMG 691
Amgen
Phase 1
28
Nevada
2026-08-07
Recruiting
A Phase 3 Study of Rezpegaldesleukin (NKTR-358) for Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis
NCT07711418Moderate-to-Severe Atopic Dermatitis
DrugRezpegaldesleukin
Nektar Therapeutics
Phase 3
510
Alabama, California, Florida, Georgia, Louisiana, Missouri, Nevada, New Jersey
2026-08-07
Recruiting
Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)
NCT07753603Thyroid Eye Disease, TED, Graves Orbitopathy
DrugLinsitinib
Sling Therapeutics, Inc.
Phase 3
130
Nevada
2026-08-04
Recruiting
A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder
NCT07759128Generalized Anxiety Disorder
DrugUlotaront
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
576
Arizona, Florida, Nevada, New York, Texas
2026-07-28
Recruiting
A Study to Evaluate Gepotidacin Exposure in Breast Milk of Healthy Lactating Women
NCT07645235Urinary Tract Infections
DrugGepotidacin
GlaxoSmithKline
Phase 1
8
Nevada
2026-07-23
Recruiting
Study of GS-0415 and How It Works in People With HIV
NCT07719491HIV -1 Infection
Gilead Sciences
Phase 1
112
California, District of Columbia, Florida, Georgia, Indiana, Massachusetts, Nevada, New Jersey
2026-07-22
Recruiting
A Study to Learn More About the Safety of a Single Dose of BIIB144 and How it is Processed in the Body of Healthy Adult Participants Ages 18 to 55 Years Old as Compared to a Placebo
NCT07662148Healthy Volunteer
Biogen
Phase 1
48
Nevada
2026-07-21
Active, closed
A Clinical Trial to Evaluate the Effects of Rejuvaskin Eczema Body Wash and Skin Recovery Cream in Adults With Eczema-Prone Skin
NCT07700745Eczema, Atopic Dermatitis, Eczema-Prone Skin
Rejuvaskin
Not applicable
35
Nevada
2026-07-06
Active, closed
A Clinical Trial to Evaluate the Effects of Super Lungs Liquid Drops on Respiratory Comfort, Airway Soothing, and Overall Well-Being
NCT07694284Coughing, Throat Irritation
SuperBonsai Inc.
Not applicable
35
Nevada
2026-07-02
Active, closed
A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum Comfort
NCT07692581Bad Breath, Tooth Sensitivity
Larine C Corporation
Not applicable
40
Nevada
2026-07-02
Recruiting
A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers
NCT07710820Smoking, Tobacco
RAI Services Company
Not applicable
1,060
Florida, Illinois, Nevada, Texas
2026-07
Recruiting
An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets.
NCT07747103Hypothyroidism
Neuvosyn Laboratories, LLC
Phase 3
466
California, Colorado, Florida, Idaho, Massachusetts, Nevada, North Carolina, South Carolina
2026-06-30
Recruiting
Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)
NCT07284602Idiopathic Pulmonary Fibrosis (IPF)
DrugsDeupirfenidone·Pirfenidone
PureTech
Phase 3
1,100
California, Massachusetts, Nevada, Pennsylvania, South Carolina, Tennessee, Texas
2026-06-26
Active, closed
A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy Levels
NCT07742657Gastrointestinal Symptoms, Bloating, Digestive Discomfort, Low Energy Levels
SuperBonsai Inc.
Not applicable
35
Nevada
2026-06-24
Recruiting
Phase 1 Study on the Safety, Tolerability, and Pharmacokinetics of JST-018 in Healthy Adults
NCT07595458Antiviral Drug
Just-Evotec Biologics
Phase 1
48
Nevada
2026-06-23
Recruiting
Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder
NCT07644052Cannabis Withdrawal
DrugNabilone
PleoPharma, Inc.
Phase 3
420
Arkansas, Connecticut, Florida, Georgia, Kentucky, Maryland, Nevada, New Jersey
2026-06-17
Recruiting
A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer
NCT07647328ER-Positive HER2-Negative Breast Cancer
DrugsCamizestrant·Ribociclib
AstraZeneca
Phase 3
150
California, Georgia, Illinois, Kentucky, Nevada, South Dakota, Tennessee, Texas
2026-06-15
Active, closed
A Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors
NCT07656727Obesity and Cardiovascular Risk
DrugBGE-102
BioAge Labs, Inc.
Phase 2
160
Arizona, Arkansas, Florida, Kentucky, Maryland, Missouri, Nevada, New York
2026-06-11
Recruiting
Evaluation of a Non-Invasive Device for Early Detection of Atopic Dermatitis Flares
NCT07645820Atopic Dermatitis
Castle Biosciences Incorporated
Observational
450
Arizona, Maryland, Michigan, Missouri, Nevada, New Hampshire, Texas, Virginia
2026-06-04
Not yet open
Evaluation of the Efficacy, Safety, and Tolerability of LevoCept
NCT04457076Contraception, Women at Risk for Pregnancy
Sebela Women's Health Inc.
Phase 3
1,525
California, Colorado, Georgia, Hawaii, Indiana, Minnesota, Missouri, Nevada
2026-06-01
Active, closed
A Clinical Trial to Evaluate the Effects of a Fibre Supplement on Microbiome and Gut Health
NCT07781488Gut Health, Microbiome, Bloating, Indigestion
Artah Nutrition Limited
Not applicable
50
Nevada
2026-06-01
Recruiting
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
NCT07613294Atherosclerosis, Cardiovascular Diseases, Lipoprotein(a)
DrugLepodisiran
Eli Lilly and Company
Phase 3
252
California, Florida, Idaho, Massachusetts, Michigan, Nevada, Pennsylvania, Utah
2026-06-01
Recruiting
A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine
NCT07609914Acute Treatment of Migraine
DrugRimegepant
Pfizer
Phase 4
400
California, Florida, Indiana, Massachusetts, Michigan, Minnesota, Mississippi, Nevada
2026-05-28
Recruiting
The Impact of Enhanced Music & Natural Visuals on Emotional Health
NCT07676110Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery
soundBrilliance LLC
Not applicable
200
Colorado, Nebraska, Nevada
2026-05-25
Recruiting
Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients
NCT07646613Migraine
Aspeya, Inc.
Phase 2
108
California, Florida, Nevada, Tennessee, Utah
2026-05-19
Recruiting
Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
NCT07527650Type 2 Diabetes Mellitus, T2DM
DrugHM15275
Hanmi Pharmaceutical Company Limited
Phase 2
180
Arizona, Florida, Georgia, Indiana, Missouri, Nebraska, Nevada, North Carolina
2026-05-18
Recruiting
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
NCT07392892Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma, Metastatic Gastric Cancer, Gastroesophageal Junction Cancer, Esophageal Adenocarcinoma
DrugsPF-08634404·Nivolumab
Pfizer
Phase 2/3
840
California, Colorado, Florida, Illinois, Maryland, Nevada, New Jersey, New York
2026-05-14
Recruiting
IS-001 Injection in Patients Undergoing Robotic-Assisted Colorectal Surgery
NCT07346066Ureter Injury
Intuitive Surgical
Phase 3
146
California, Connecticut, Florida, Nevada, Ohio, Texas, Washington
2026-05-14
Recruiting
A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis
NCT07501702Myasthenia Gravis, Generalized
DrugPovetacicept
Vertex Pharmaceuticals Incorporated
Phase 2
30
California, Florida, Hawaii, Illinois, Nevada, South Carolina, Tennessee, Texas
2026-05-13
Recruiting
A Study to Evaluate the Safety and Tolerability of Different Doses of CX11 Tablets
NCT07652047Obesity & Overweight
DrugCX11
Corxel Pharmaceuticals
Phase 1
90
Nevada, Texas
2026-05-11
Recruiting
A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer
NCT07265674Advanced Biliary Tract Cancer, Biliary Tract Cancer (BTC)
J-Pharma Co., Ltd.
Phase 3
480
California, Florida, Illinois, Kentucky, Louisiana, Michigan, Minnesota, Nevada
2026-05-11
Recruiting
A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism
NCT07081997Hypoparathyroidism, Endocrine System Diseases, Parathyroid Diseases
Ascendis Pharma Bone Diseases A/S
Phase 3
36
Colorado, Illinois, Minnesota, Nevada, New York, North Carolina, Texas, Washington
2026-05-07
Recruiting
Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis
NCT07610837Liver Fibrosis, Hepatic Cirrhosis
AstraZeneca
Phase 2
104
Arizona, Florida, Missouri, Nevada, North Carolina, Ohio, Oklahoma, Tennessee
2026-05-07
Recruiting
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
NCT07513376Non-small Cell Lung Cancer
DrugsPembrolizumab Formulated with Berahyaluronidase Alfa·Intismeran autogene
Merck Sharp & Dohme LLC
Phase 3
876
California, Colorado, Connecticut, Illinois, Missouri, Montana, Nebraska, Nevada
2026-05-04
Recruiting
A Study of VV-14305 for the Treatment of Thyroid Eye Disease
NCT07404111Thyroid Eye Disease (TED)
Kriya Therapeutics, Inc.
Phase 1/2
135
Michigan, Nevada, Pennsylvania
2026-05-01
Recruiting
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
NCT07573176Depressive Disorder, Major
DrugSeltorexant
Janssen Research & Development, LLC
Phase 3
600
Arkansas, California, Florida, Georgia, Illinois, Maryland, Massachusetts, Nevada
2026-04-30
Recruiting
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
NCT07502508Type 2 Diabetes
DrugIcovamenib
Biomea Fusion Inc.
Phase 2
60
Alabama, California, Florida, Georgia, Nevada, Ohio, Texas, Virginia
2026-04-30
Recruiting
ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL
NCT07342478CLL / SLL, CLL (Chronic Lymphocytic Leukemia), CLL, Refractory, CLL, Relapsed
DrugsRocbrutinib·Pirtobrutinib
Newave Pharmaceutical Inc
Phase 3
306
Illinois, Maryland, Nevada, Ohio, Pennsylvania, Washington
2026-04-23
Recruiting
PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis
NCT07611214Lupus Nephritis
DrugsLupkynis·Anifrolumab
Aurinia Pharmaceuticals Inc.
Phase 4
150
California, Colorado, Florida, Georgia, Louisiana, Maryland, Missouri, Nevada
2026-04-22
Recruiting
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
NCT07481630Obesity, Knee Osteoarthritis (OA)
DrugNNC0487-0111
Novo Nordisk A/S
Phase 3
400
Arizona, California, Connecticut, Florida, Georgia, Idaho, Massachusetts, Nevada
2026-04-13
Recruiting
Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)
NCT07428499Hereditary Angioedema (HAE), Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2, HAE
ADARx Pharmaceuticals, Inc.
Phase 3
90
Arizona, Arkansas, California, Florida, Maryland, Michigan, Missouri, Nevada
2026-04-02
Recruiting
Study to Assess Safety, Pharmacokinetics, and Treatment Effect of Cabtreo
NCT07524946Acne Vulgaris
Bausch Health Americas, Inc.
Phase 4
100
Arkansas, California, Florida, Kentucky, Michigan, Nevada, New York, North Carolina
2026-04-01
Recruiting
A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU)
NCT07552077Angiokeratomas
DrugPTX-022
Palvella Therapeutics, Inc.
Phase 2
15
California, Georgia, Nevada, Texas
2026-04
Active, closed
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets
NCT07502495Type 2 Diabetes
DrugIcovamenib
Biomea Fusion Inc.
Phase 2
64
Alabama, California, Florida, Georgia, Nevada, Ohio, Texas, Virginia
2026-03-27
Recruiting
A Study Evaluating MDX2301 in Healthy Adults and Adults at Higher Risk for Severe COVID-19.
NCT07445971COVID -19, COVID-19 (Prevention)
ModeX Therapeutics, An OPKO Health Company
Phase 1
80
Nevada, Texas
2026-03-24
Active, closed
A Clinical Trial to Evaluate the Effects of a Supplement on Children's Focus and Energy
NCT07766642Difficulty Focusing, Poor Concentration, Poor Memory, Low Energy
Auri Nutrition
Not applicable
35
Nevada
2026-03-13
Recruiting
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
NCT07491445Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma
DrugsCetuximab·Nab-paclitaxel·Gemcitabine
Revolution Medicines, Inc.
Phase 3
900
Arizona, California, Florida, Maryland, Massachusetts, Michigan, Minnesota, Nevada
2026-03-09
Recruiting
A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo
NCT07431177Non-segmental Vitiligo
DrugGIA632
Novartis Pharmaceuticals
Phase 2
210
Alabama, California, Florida, Indiana, Michigan, Nebraska, Nevada, New York
2026-03-09
Active, closed
A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight
NCT07441252Overweight or Obesity and Elevated Liver Fat
DrugMaridebart cafraglutide
Amgen
Phase 2
180
Arizona, California, Florida, Louisiana, Maryland, Missouri, Nevada, Texas
2026-03-05
Active, closed
Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief
NCT07300540Dentin Sensitivity
HALEON
Not applicable
500
Nevada
2026-03-04
Recruiting
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
NCT07484217Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
DrugSolriamfetol
Axsome Therapeutics, Inc.
Phase 3
508
Arizona, California, Florida, Georgia, Illinois, Maryland, Massachusetts, Nevada
2026-02-23
Recruiting
A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies
NCT07154823Acute Myeloid Leukaemia (AML), Follicular Lymphoma ( FL)
Tempus AI
Observational
550
Iowa, Maryland, Missouri, Nevada, North Carolina, Ohio, Pennsylvania, South Dakota
2026-01-27
Recruiting
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
NCT07494305Bipolar I Disorder
DrugLB-102
LB Pharmaceuticals Inc.
Phase 2
320
Arkansas, California, Florida, Georgia, Illinois, Michigan, Missouri, Nevada
2026-01-23
Recruiting
A Study to Evaluate the Effect of KarXT on Urological Safety
NCT07221877Schizophrenia
DrugKarXT
Bristol-Myers Squibb
Phase 4
60
Arkansas, California, Florida, Illinois, Nevada, New Jersey, Pennsylvania, Texas
2026-01-20
Recruiting
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)
NCT07216703Cervical Cancer
DrugsMvasi·Sacituzumab tirumotecan·Paraplatin·Avastin
Merck Sharp & Dohme LLC
Phase 3
1,023
Alabama, California, Florida, Georgia, Louisiana, Maryland, Minnesota, Nevada
2026-01-19
Recruiting
Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Users
NCT06594068Systemic Lupus Erythematosus
DrugAnifrolumab
AstraZeneca
Phase 4
16
Nevada
2026-01-16
Recruiting
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
NCT07195695Non-small Cell Lung Cancer
DrugsZongertinib·Atezolizumab·Durvalumab·Nivolumab
Boehringer Ingelheim
Phase 3
400
California, District of Columbia, Florida, Georgia, Idaho, Illinois, Massachusetts, Nevada
2026-01-16
Active, closed
A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)
NCT07298330Chronic Hepatitis D Infection
DrugBulevirtide
Mirum Pharmaceuticals, Inc.
Phase 3
80
California, Colorado, Nevada, Ohio, Texas, Utah
2026-01-14
Recruiting
An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)
NCT07392255Geographic Atrophy Secondary to Age-related Macular Degeneration
Complement Therapeutics
Phase 1/2
75
Indiana, Nevada, Texas, Wisconsin
2025-12-30
Recruiting
Renal Pelvic Denervation Pilot Trial
NCT07005050Uncontrolled Hypertension
Verve Medical, Inc
Not applicable
60
Alabama, Arizona, Minnesota, Nevada
2025-12-30
Recruiting
ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
NCT07294170Myasthenia Gravis, MG, gMG, Generalized Myasthenia Gravis
DrugsEmpasiprubart·Efgartigimod
argenx
Observational
70
California, Florida, Massachusetts, Michigan, Nevada, New York, North Carolina, Ohio
2025-12-19
Recruiting
ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod
NCT07284420AChR-Ab Seropositive Generalized Myasthenia Gravis, Myasthenia Gravis, MG, gMG
DrugsEmpasiprubart·Efgartigimod
argenx
Phase 2
70
California, Florida, Massachusetts, Michigan, Nevada, New York, North Carolina, Ohio
2025-12-19
Recruiting
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
NCT07276997Major Depressive Disorder
DrugIcalcaprant
AbbVie
Phase 2
195
Alabama, Arizona, Arkansas, California, Florida, Georgia, Illinois, Nevada
2025-12-18
Recruiting
A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B
NCT07285460Hemophilia
DrugsAntithrombin·Clotting factor concentrates·Fitusiran
Sanofi
Phase 3
85
California, Nevada, New Jersey, Texas
2025-12-18
Active, closed
HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Study
NCT07215468HIV -1 Infection
DrugVRC07-523LS
TaiMed Biologics Inc.
Phase 2
88
California, Florida, Nevada, New York, Texas
2025-12-16
Recruiting
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
NCT07337109Dentin Hypersensitivity
HALEON
Observational
375
Nevada
2025-12-16
Recruiting
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
NCT07300969Major Depressive Disorder (MDD)
DrugDT-101
Draig Therapeutics Ltd
Phase 2
300
Arkansas, California, Florida, Georgia, Maryland, Massachusetts, Mississippi, Nevada
2025-12-16
Recruiting
A Study of NTX-1472 in Social Anxiety Disorder
NCT07323784Social Anxiety Disorder (SAD)
Newleos Therapeutics, Inc.
Phase 2
100
California, Florida, Massachusetts, Nevada, New York, Tennessee, Texas
2025-12-09
Recruiting
A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)
NCT07209111Neoplasm Malignant
DrugsCalderasib·Cetuximab
Merck Sharp & Dohme LLC
Phase 2
150
Maryland, Michigan, Nevada, New Jersey, Utah, Virginia
2025-12-04
Active, closed
A 2-part, Phase 1b Clinical Study Designed to Evaluate the Safety, PK, and Efficacy of CRB-913 in Participants With Obesity
NCT07310901Obese But Otherwise Healthy Participants
Corbus Pharmaceuticals Inc.
Phase 1
252
Alabama, Arizona, California, Florida, Kentucky, Nevada, New York, North Carolina
2025-12-04
Recruiting
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
NCT07258849Rheumatoid Arthritis (RA)
Eli Lilly and Company
Phase 1
141
Alabama, Arizona, Florida, Nevada
2025-12-02
Recruiting
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
NCT07227012Carcinoma, Hepatocellular, Hepatocellular Cancer, Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma
DrugsPF-08634404·Yervoy·Ipilimumab
Pfizer
Phase 1/2
138
California, Florida, Illinois, Minnesota, Missouri, Nevada, North Carolina, Ohio
2025-12-01
Recruiting
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs
NCT06930625Acromegaly
Debiopharm International SA
Phase 3
119
California, Illinois, Massachusetts, Missouri, Nevada, New York, Ohio, Oregon
2025-11-26
Recruiting
Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women
NCT07209397Overactive Bladder, Overactive Bladder (OAB), Urge Urinary Incontinence, Mixed Urinary Incontinence (Urge-Predominant)
InMode MD Ltd.
Not applicable
202
California, District of Columbia, Idaho, Illinois, Kansas, Massachusetts, Nebraska, Nevada
2025-11-25
Recruiting
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
NCT06990269Geographic Atrophy Secondary to Age-related Macular Degeneration
ADARx Pharmaceuticals, Inc.
Phase 2
240
Arizona, California, Florida, Maryland, Nevada, Pennsylvania, Texas, Utah
2025-11-10
Recruiting
Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa
NCT07170917Hidradenitis Suppurativa
DrugBrivekimig
Sanofi
Phase 2
208
Arizona, California, Florida, Georgia, Iowa, Louisiana, Missouri, Nevada
2025-11-06
Active, closed
Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide
NCT07220759Overweight, Obesity, Type 2 Diabetes
DrugCagrilintide
Novo Nordisk A/S
Phase 3
330
Alabama, Arizona, California, Florida, Hawaii, Indiana, Nevada, New York
2025-11-05
Recruiting
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
NCT07100080Non-Small Cell Lung Cancer
DrugsIza-bren·Pemetrexed·Cisplatin·Carboplatin
Bristol-Myers Squibb
Phase 2/3
500
California, Colorado, Florida, Georgia, Illinois, Massachusetts, Missouri, Nevada
2025-11-05
Recruiting
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
NCT07223840Smoking
DrugBrenipatide
Eli Lilly and Company
Phase 2
222
Arkansas, Florida, Georgia, Michigan, Missouri, Nevada, New York, South Carolina
2025-11-03
Recruiting
A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec
NCT07332000Prostate Cancer Patients Treated by Radiotherapy, Prostate Cancer (Adenocarcinoma)
DrugsAglatimagene besadenovec·Valacyclovir
Candel Therapeutics, Inc.
Phase 2
45
Arizona, Colorado, Maryland, Nevada, New Jersey, South Carolina
2025-10-30
Recruiting
Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a)
NCT07327840Lipoprotein Disorder
Kylonova (Xiamen) Biopharma co., LTD.
Phase 2
204
California, Florida, Georgia, Louisiana, Nevada, North Carolina
2025-10-29
Recruiting
Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
NCT07211178Breast Cancer, TNBC - Triple-Negative Breast Cancer, HR Positive/HER-2 Negative Breast Cancer, HER2 + Breast Cancer
Tempus AI
Observational
900
Alabama, California, Florida, Illinois, Indiana, Michigan, Missouri, Nevada
2025-10-27
Recruiting
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
NCT07219173Asthma
DrugBrenipatide
Eli Lilly and Company
Phase 2
531
Arizona, California, Colorado, Florida, Illinois, Kentucky, Massachusetts, Nevada
2025-10-22
By invitation
Vivio At-Home Study
NCT07730268Heart Failure
Ventric Health, LLC
Not applicable
500
California, Nevada
2025-10-20
Recruiting
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
NCT07215559Obesity, Overweight, Diabetes Mellitus, Type 2
DrugsMacupatide·Eloralintide
Eli Lilly and Company
Phase 2
200
Arizona, Florida, Georgia, Nevada, New Jersey, Ohio, Texas, Utah
2025-10-16
Recruiting
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
NCT07215234Geographic Atrophy
Sanofi
Phase 1/2
104
Arizona, California, Florida, Georgia, Illinois, Maryland, Nevada, North Carolina
2025-10-09
By invitation
5-Year Postoperative Outcomes of Patients Who Completed the CREST Study
NCT07480343Open-angle Glaucoma (OAG)
Iantrek, Inc.
Observational
250
California, Florida, Georgia, Maryland, Nevada, Pennsylvania, Tennessee, Utah
2025-09-15
Active, closed
Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age
NCT07207408Prevention of Pneumonic Plague Resulting From Aerosol Exposure to Yersinia Pestis
Dynavax Technologies Corporation
Phase 2
148
Florida, Kansas, Nevada, Ohio
2025-09-11
Active, closed
A Phase I/II Study on Safety AND Immunogenicity of AZD4117 and AZD5315 Vaccines (PANDA)
NCT07128615Influenza A
AstraZeneca
Phase 1/2
405
California, Florida, Georgia, Illinois, Kansas, Missouri, Nebraska, Nevada
2025-09-04
Recruiting
A Study to Learn About the Safety of BIIB142 and How it is Processed in the Body of Healthy Adult Participants Aged 18 to 55 Years Old
NCT07133828Healthy Volunteer
Biogen
Phase 1
78
Nevada
2025-08-29
Recruiting
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
NCT06887192Psychosis Associated With Alzheimer's Disease
DrugML-007C-MA
MapLight Therapeutics
Phase 2
300
Arizona, California, Colorado, Florida, Georgia, Louisiana, Nevada, New Jersey
2025-08-15
Recruiting
Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
NCT07160179Geographic Atrophy, Age-Related Macular Degeneration
DrugSyfovre
AbbVie
Phase 1/2
66
Indiana, Nevada, Texas
2025-08-13
Recruiting
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
NCT07096674Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
DrugORX750
Centessa Pharmaceuticals (UK) Limited
Phase 2
90
Alabama, California, Florida, Georgia, Michigan, Nevada, North Carolina, Ohio
2025-08-12
Recruiting
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications
NCT07380412ADHD, Sleep Disturbance, Brain Fog
Outliers, Inc.
Not applicable
90
Nevada
2025-08-12
Recruiting
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
NCT07172516Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
DrugAzetukalner
Xenon Pharmaceuticals Inc.
Phase 3
400
Arizona, Arkansas, California, Florida, Georgia, Illinois, Missouri, Nevada
2025-08-08
Recruiting
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
NCT07094516Alzheimer's Disease
DrugVHB937
Novartis Pharmaceuticals
Phase 2
407
Arizona, California, Florida, Hawaii, Kansas, Massachusetts, Missouri, Nevada
2025-08-07
Recruiting
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
NCT07005102Non-Squamous Non-Small Cell Lung Cancer, c-MET
DrugsTelisotuzumab Adizutecan·Osimertinib·Pemetrexed·Cisplatin
AbbVie
Phase 2/3
854
Arizona, California, Colorado, Florida, Hawaii, Iowa, Nebraska, Nevada
2025-08-03
Recruiting
An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related Symptoms
NCT07078682Uterine Fibroids, Leiomyoma, Menstrual Pain
Zenchi, Inc.
Not applicable
42
Nevada
2025-08-01
Recruiting
A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)
NCT07144137Geographic Atrophy Secondary to Age-related Macular Degeneration
Complement Therapeutics
Observational
75
California, Illinois, Indiana, Nevada, North Carolina, Pennsylvania, Texas, Wisconsin
2025-07-30
Recruiting
A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors
NCT07015697Recurrent or Metastatic Solid Tumors
DrugTrastuzumab deruxtecan
Daiichi Sankyo
Phase 1
76
California, Georgia, Nevada, North Carolina, Ohio, Tennessee
2025-07-17
Recruiting
A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases
NCT06764940HER2-negative Breast Cancer Patients With Brain Metastases
DrugsUtidelone·Capecitabine
Biostar Pharma, Inc.
Phase 2
120
California, Colorado, Georgia, Illinois, Maryland, Nevada, New York, Texas
2025-07-14
Active, closed
A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH
NCT07000136Heterozygous Familial Hypercholesterolaemia
DrugAZD0780
AstraZeneca
Phase 3
473
California, Florida, Georgia, Illinois, Louisiana, Nevada, New York, North Carolina
2025-06-10
Recruiting
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
NCT06340568Endometrial Cancer
DrugsDoxorubicin·Docetaxel·Paclitaxel
BioNTech SE
Phase 3
480
Connecticut, District of Columbia, Florida, Illinois, Louisiana, Nevada, New York, Ohio
2025-06-10
Recruiting
The Role of hCG in Thawed Embryo Transfer
NCT07004192Infertility (IVF Patients)
Fertility Center of Las Vegas
Phase 4
220
Nevada
2025-06-02
Active, closed
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
NCT06917404Osteoarthritis, Knee
DrugPentosan Polysulfate Sodium
Paradigm Biopharmaceuticals Ltd.
Phase 3
466
Arizona, California, Florida, Illinois, Maryland, Michigan, Nebraska, Nevada
2025-05-29
Recruiting
An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Joint
NCT06485843Osteoarthritis, Osteo Arthritis Knee
Ageless Biotech, Inc.
Phase 2
400
Nevada
2025-05-21
Active, closed
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
NCT06966479Severe Asthma
DrugVerekitug
Upstream Bio Inc.
Phase 2
396
California, Florida, Idaho, Maryland, Michigan, Nevada, New York, Ohio
2025-05-21
Active, closed
Ph1, Randomized, Double-Blind and Controlled, Dose Escalation and Expansion Study to Assess the Safety and Pharmacokinetics of JST-010 in Healthy Adults
NCT06943378Pre-exposure Prophylaxis Against Pneumonic Plague in Healthy Adults
Just-Evotec Biologics
Phase 1
104
Nevada
2025-05-16
Recruiting
Randomized Withdrawal Study in Patients With Schizophrenia
NCT06961968Schizophrenia
DrugIloperidone
Vanda Pharmaceuticals
Phase 3
400
Arkansas, California, Florida, Georgia, Illinois, Mississippi, Missouri, Nevada
2025-05-14
Active, closed
A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight
NCT06962280Type 1 Diabetes, Obesity, Overweight
DrugTirzepatide
Eli Lilly and Company
Phase 3
465
California, Colorado, Florida, Iowa, Minnesota, Missouri, Nevada, North Carolina
2025-05-12
Recruiting
Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration
NCT06662162Age-Related Macular Degeneration, Age-related Macular Degeneration (ARMD), Intermediate AMD, Geographic Atrophy Secondary to Age-related Macular Degeneration
i-Lumen Scientific AUS PTY LTD
Not applicable
100
California, Connecticut, Illinois, Nevada, Ohio, Texas
2025-05-07
Recruiting
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
NCT06499285Myelodysplastic Syndromes
DrugElritercept
Takeda
Phase 3
225
California, Connecticut, Florida, Illinois, Kentucky, Maryland, Missouri, Nevada
2025-05-06
Active, closed
Study to Evaluate the Efficacy of an Avocado Dietary Supplement
NCT07354308Overweight, Metabolic Health, Insulin Resistance
SP Nutraceuticals Inc.
Not applicable
60
Nevada
2025-05-01
Recruiting
SPYRAL GEMINI Pilot Study
NCT06907147Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular
Not applicable
175
California, Florida, Georgia, Massachusetts, Michigan, Mississippi, Nevada, New Jersey
2025-05-01
Active, closed
A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants With Advanced MASH Liver Fibrosis
NCT06903065MASH
DrugAfimkibart
Hoffmann-La Roche
Phase 1
50
Arizona, Georgia, Louisiana, Nevada, Tennessee, Texas
2025-04-14
Recruiting
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
NCT06657144Metastatic Solid Tumor, Advanced Solid Tumor
DrugsCHS-114·Adrucil·Toripalimab·Cisplatin
Coherus Oncology, Inc.
Phase 1
154
Arizona, California, Colorado, Georgia, Louisiana, Michigan, Nevada, New Mexico
2025-04-01
Recruiting
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
NCT06750289Eosinophilic Asthma
AstraZeneca
Phase 3
400
Arizona, California, Colorado, Florida, Michigan, Nevada, New Jersey, New York
2025-03-28
Active, closed
Evaluating SUI-100™, A Non-Invasive Device for the Treatment of Stress Urinary Incontinence
NCT06862648Stress Urinary Incontinence (SUI)
Acoustic Wave Cell Therapy, Inc.
Not applicable
130
Arizona, Florida, Idaho, Kansas, Montana, Nevada, Ohio, Texas
2025-03-25
Recruiting
Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis
NCT06911424Bacterial Conjunctivitis
Baxis Pharmaceuticals, Inc.
Phase 3
400
Arkansas, California, Florida, Georgia, Idaho, Illinois, Maryland, Nevada
2025-03-21
Active, closed
A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration
NCT06795048Neovascular Age-related Macular Degeneration (nAMD)
DrugsVabysmo·Faricimab
Hoffmann-La Roche
Phase 4
274
California, Florida, Illinois, Massachusetts, Nevada, New Jersey, New Mexico, Tennessee
2025-03-14
Recruiting
52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism
NCT06689085Hypogonadism, Male
Halozyme Therapeutics
Phase 3
100
California, Colorado, Florida, Illinois, Massachusetts, Minnesota, Missouri, Nevada
2025-03-07
Recruiting
Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN
NCT06797518Glomerulonephritis, IGA, Immunoglobulin A Nephropathy
DrugIptacopan
Novartis Pharmaceuticals
Phase 2
20
Alabama, California, Florida, Georgia, Idaho, Nevada, Ohio, Texas
2025-02-21
Recruiting
A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
NCT06765668Parkinson Disease
Impax Laboratories, LLC
Phase 4
220
Arizona, Arkansas, California, Florida, Illinois, Kansas, Michigan, Nevada
2025-02-12
Recruiting
A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
NCT06849258Benign Prostatic Hyperplasia
Rivermark Medical
Not applicable
215
California, Colorado, Florida, Illinois, Louisiana, Michigan, Nevada, New York
2025-02-10
Active, closed
A Clinical Trial to Evaluate the Effects of a Herbal Tincture on Energy Levels, Weight Management, and Markers of Metabolic Health
NCT06949540Stress, Fatigue
Apothekary
Not applicable
40
Nevada
2025-02-07
By invitation
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
NCT06679881Hereditary Angioedema (HAE)
DrugDeucrictibant
Pharvaris Netherlands B.V.
Phase 3
170
Alabama, Arizona, Arkansas, California, Colorado, Illinois, Missouri, Nevada
2025-02-01
Recruiting
BOOM-IBD2 Pivotal Clinical Trial
NCT06571669Ulcerative Colitis, Inflammatory Bowel Diseases
Boomerang Medical
Not applicable
137
California, Kansas, Minnesota, Mississippi, Missouri, Nevada, New York, North Carolina
2025-01-31
Active, closed
Retrospective Study of AlloMend Acellular Dermal Matrix (ADM) Allograft and Pre-Pectoral Breast Reconstruction
NCT06853964Pre-Pectoral Breast Reconstruction Following Mastectomy
AlloSource
Observational
100
Nevada
2025-01-27
Recruiting
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
NCT06516653End Stage Renal Disease
Laminate Medical Technologies
Not applicable
300
California, Florida, Georgia, Massachusetts, Mississippi, Nevada, South Carolina, Texas
2025-01-13
Active, closed
A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Throat Spray on the Incidence and Duration of Sickness
NCT07246850Sore-throat, Common Cold
Beekeeper's Naturals Inc
Not applicable
100
Nevada
2024-12-30
Recruiting
A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease
NCT06500702Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion
DrugsBrivekimig·Frexalimab·Rilzabrutinib
Sanofi
Phase 2
84
Alabama, California, Florida, Georgia, Illinois, Michigan, Minnesota, Nevada
2024-12-19
Recruiting
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of VH4011499 Compared to Placebo in Adults Without HIV
NCT06724640HIV Infections
ViiV Healthcare
Phase 1
168
Nevada, Texas
2024-12-16
Active, closed
A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.
NCT06637631Crohn's Disease
DrugBalinatunfib
Sanofi
Phase 2
260
Arizona, Connecticut, Florida, Illinois, Michigan, Mississippi, Nevada, New York
2024-12-10
Active, closed
Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)
NCT06428396Metastatic Breast Cancer
DrugsBelzutifan·Exemestane·Everolimus·Fulvestrant
Merck Sharp & Dohme LLC
Phase 2
120
Arizona, California, Georgia, Louisiana, Nevada, New Jersey, Texas, Wisconsin
2024-11-27
Recruiting
A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer
NCT06532006Gastroesophageal-junction Cancer, Monoclonal Antibody, Gastric Cancer, HER2-positive Gastric Cancer
DrugsHLX22·Trastuzumab·Capecitabine·Oxaliplatin
Shanghai Henlius Biotech
Phase 3
550
California, Colorado, Florida, Illinois, Iowa, Missouri, Nebraska, Nevada
2024-11-22
Active, closed
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration
NCT06660667Neovascular Age-related Macular Degeneration
Sanofi
Phase 1/2
66
Arizona, California, Florida, Georgia, Illinois, Maryland, Massachusetts, Nevada
2024-11-21
Recruiting
A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)
NCT05582993Von Willebrand Disease (VWD)
DrugsAdvate·Vonicog Alfa
Takeda
Phase 3
24
Alabama, Florida, Illinois, Indiana, Iowa, Michigan, Minnesota, Nevada
2024-11-06
Recruiting
Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
NCT06575192Breast Reconstruction
AbbVie
Phase 3
264
California, Colorado, Florida, Illinois, Maryland, Missouri, Nevada, New Jersey
2024-11-05
Active, closed
Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)
NCT06596694Gastrointestinal Cancer
DrugPatritumab deruxtecan
Merck Sharp & Dohme LLC
Phase 1/2
180
California, Colorado, District of Columbia, Florida, Georgia, Illinois, Nevada, New York
2024-11-03
Recruiting
A Prospective, Single-arm, Clinical Trial of Electrospun Fiber Matrix (Restrata) in the Treatment of Surgical Defects Secondary to Resection of Malignant Cutaneous Neoplasms
NCT06578650Surgical Wound
Acera Surgical, Inc.
Observational
34
Nevada
2024-10-31
Active, closed
Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroidism
NCT06531941Hypoparathyroidism
MBX Biosciences
Phase 2
60
Florida, Georgia, Mississippi, Missouri, Nevada, New York, Ohio, Texas
2024-10-31
Recruiting
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
NCT06651567Agitation Associated With Alzheimer's Dementia
DrugITI-1284
Intra-Cellular Therapies, Inc.
Phase 2
320
California, Florida, Massachusetts, Nevada, New Jersey, North Carolina, Texas
2024-10-22
Active, closed
A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Berahyaluronidase Alfa (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)
NCT06504394Classical Hodgkin Lymphoma Recurrent, Classical Hodgkin Lymphoma Refractory, Primary Mediastinal Large B-cell Lymphoma Recurrent, Primary Mediastinal Large B-cell Lymphoma Refractory
Drugs) Berahyaluronidase alfa·Pembrolizumab
Merck Sharp & Dohme LLC
Phase 2
66
Iowa, Nevada, New York
2024-10-14
Active, closed
A Study to Assess the Safety and Pharmacokinetics of a Human Monoclonal Antibody (VH4527079) in Healthy Adults and Persons With HIV
NCT06652958HIV Infections
ViiV Healthcare
Phase 1
102
Nevada, Texas
2024-10-02
Recruiting
A Multi-Site Clinical Evaluation of the LIAISON NES FLU A/B, RSV & COVID-19 Assay in Symptomatic Patients
NCT06672692Influenza a, Influenza B, RSV, COVID 19
DiaSorin Molecular LLC
Not applicable
1,000
Nevada, Pennsylvania, Texas
2024-09-30
Recruiting
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
NCT06584357Mild Cognitive Impairment, Alzheimer's Disease, Alzheimer's Disease, Early Onset, Memory Loss
GAP Innovations, PBC
Observational
1,200
Florida, Illinois, Michigan, Nevada, New York, Ohio, Pennsylvania, Rhode Island
2024-09-26
Active, closed
Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).
NCT06333951Thoracic Tumors, Non-small Cell Lung Cancer
DrugsAnvumetostat·Sotorasib·Pemetrexed·Paclitaxel
Amgen
Phase 1
49
California, Colorado, Connecticut, Minnesota, Missouri, Nevada, New York, Oklahoma
2024-09-17
Active, closed
A Long-term Follow up Study of EXG102-031 in Patients With wAMD (Everest LTFU)
NCT06817343Neovascular Age-Related Macular Degeneration (nAMD), Neovascular (Wet) Age-related Macular Degeneration (AMD)
DrugAflibercept
Exegenesis Bio
Phase 1
12
Nevada, Pennsylvania
2024-09-10
Recruiting
A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants
NCT06576271Systemic Lupus Erythematosus
DrugBelimumab
GlaxoSmithKline
Phase 1
142
Arizona, Colorado, Nevada, Ohio, Oklahoma, Texas
2024-09-02
Active, closed
Study to Evaluate the Effect on Obesity of QW Nimacimab and QW Nimacimab Co-administered With Semaglutide vs Placebo
NCT06577090Obesity
Skye Bioscience, Inc.
Phase 2
136
Alabama, California, Connecticut, Georgia, Kentucky, Nebraska, Nevada, New Hampshire
2024-08-22
Active, closed
Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies
NCT06577987Advanced Solid Tumor, Metastatic Solid Tumor, Refractory Solid Tumor, Cancer
Circle Pharma
Phase 1
220
Florida, Massachusetts, Michigan, Nevada, Ohio, Oregon, Tennessee, Texas
2024-08-14
By invitation
Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus
NCT06475742Lupus Erythematosus, Systemic
DrugCenerimod
Viatris Innovation GmbH
Phase 3
680
Colorado, Florida, Louisiana, Nevada, Texas
2024-07-30
Active, closed
A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression
NCT06365853Recurrent Ovarian Cancer, Folate Receptor-Alpha Positive
DrugsMIRV·Mirvetuximab Soravtansine
AbbVie
Phase 2
108
California, Kentucky, Maryland, Missouri, Nevada, New Jersey, New York, North Carolina
2024-07-29
Active, closed
A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)
NCT06459180Cervical Cancer
DrugsTisotumab Vedotin·Vinorelbine·Topotecan·Sacituzumab tirumotecan
Merck Sharp & Dohme LLC
Phase 3
686
Alabama, Alaska, Arizona, California, Florida, Georgia, Louisiana, Nevada
2024-07-24
Recruiting
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
NCT06226883Inflammatory Bowel Diseases, Crohn's Disease
DrugZotemtegrast
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
Phase 2
385
California, Colorado, Florida, Georgia, Louisiana, Missouri, Nevada, North Carolina
2024-07-18
Active, closed
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
NCT06456346Essential Thrombocythemia
DrugsBomedemstat·Hydroxyurea
Merck Sharp & Dohme LLC
Phase 3
300
Arizona, California, Colorado, Connecticut, Indiana, Michigan, Nevada, North Carolina
2024-07-16
Active, closed
A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease
NCT06248619Thyroid Eye Disease
DrugTeprotumumab
Amgen
Phase 3
89
Arizona, Illinois, Michigan, Nevada, New Jersey, Oregon, Pennsylvania, Tennessee
2024-07-05
Recruiting
A Clinical Study of YL205 in Patients With Advanced Solid Tumors
NCT06459973Advanced Solid Tumors
MediLink Therapeutics (Suzhou) Co., Ltd.
Phase 1/2
252
Colorado, Connecticut, Florida, Kentucky, Missouri, Nevada, New Mexico, Oklahoma
2024-06-04
Active, closed
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
NCT06401044Thyroid Eye Disease
DrugAMG 732
Amgen
Phase 1/2
94
Arkansas, California, Florida, Illinois, Massachusetts, Nevada, Pennsylvania, Texas
2024-05-30
Recruiting
Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors
NCT06384352Advanced Solid Tumors
DrugsPemetrexed·Cisplatin·Carboplatin·Pembrolizumab
MediLink Therapeutics (Suzhou) Co., Ltd.
Phase 1
500
Colorado, Connecticut, Florida, Nevada, Ohio, Texas
2024-05-01
Active, closed
RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer
NCT05966194Oral Mucositis
DrugsRRx-001·Cisplatin
EpicentRx, Inc.
Phase 2
216
Arizona, Florida, Illinois, Indiana, Louisiana, Maryland, Michigan, Nevada
2024-04-02
By invitation
Clinical Registry Collecting Real World Evidence on Wound Care Treatments
NCT06328010Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed
Siddhey LLC
Observational
5,000
Arizona, California, Florida, Illinois, Nevada, Texas
2024-04-01
Active, closed
OPtilume™ BPH Catheter SystEm for Treatment of Men eXperiencing Symptomatic BPH
NCT06560476Benign Prostatic Hyperplasia
Urotronic Inc.
Observational
500
Florida, Nebraska, Nevada, New York, Oregon, Texas, Virginia
2024-03-30
Active, closed
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis
NCT06254950Ulcerative Colitis
DrugZasocitinib
Takeda
Phase 2
213
California, Florida, Georgia, Kentucky, Maryland, Nevada, Rhode Island, South Carolina
2024-03-29
Active, closed
ProVIDE II Bridging Study
NCT06236802BPH With Symptomatic Lower Urinary Tract Symptoms
ProVerum Medical
Not applicable
40
Florida, Illinois, Nevada, Texas
2024-03-06
Active, closed
Dexcom Continuous Glucose Monitoring System Use in aReal-World, Global Registry (Dexcom Global Registry)
NCT06483945Diabetes
DexCom, Inc.
Observational
5,000
Georgia, Nevada
2024-02-28
Active, closed
First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
NCT06239467Advanced Cancer, Breast Cancer, Advanced Solid Tumors, PI3K Gene Mutation
DrugsAtirmociclib·Tucatinib·Ribociclib·Fulvestrant
OnKure, Inc.
Phase 1
200
California, Colorado, Massachusetts, Nevada, New York, Tennessee, Virginia, Washington
2024-02-26
Active, closed
SkinTE® for the Treatment of Wagner 1 Diabetic Foot Ulcers (COVER DFUS II)
NCT06140303Diabetic Foot
PolarityTE
Phase 3
100
Arizona, California, Florida, Maryland, Nevada, New York, Ohio, Texas
2024-02-22
Active, closed
Parkinson's Disease Progression Study
NCT06219629Parkinson Disease
Koneksa Health
Observational
82
Colorado, Florida, Georgia, Kansas, Massachusetts, Michigan, Nevada
2024-02-20
Active, closed
A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease
NCT06088979Thyroid Eye Disease
Tourmaline Bio, Inc., a Novartis Company
Phase 2
79
Arizona, California, Colorado, Florida, Massachusetts, Michigan, Nevada, New Jersey
2024-02-19
Active, closed
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib
NCT06120140Carcinoma, Non-Small-Cell Lung
DrugsClobetasol·Minocycline·Chlorhexidine·Clindamycin
Janssen Research & Development, LLC
Phase 2
305
Arizona, California, Georgia, Illinois, Missouri, Nevada, New Jersey, New York
2024-02-16
Active, closed
Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
NCT06151574Lung Cancer, Non-squamous, Non-small Cell
DrugsZongertinib·Pemetrexed·Keytruda·Cisplatin
Boehringer Ingelheim
Phase 3
428
Alabama, Arizona, California, Missouri, Nevada, New York, North Carolina, Ohio
2024-02-09
Recruiting
Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study
NCT06312722Benign Prostatic Hyperplasia
Urotronic Inc.
Not applicable
92
Arkansas, Florida, Louisiana, Nevada, Oregon, Texas
2024-02-07
Active, closed
Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration
NCT06116890Neovascular Age-Related Macular Degeneration (nAMD)
DrugsKHK4951·Aflibercept
Kyowa Kirin Co., Ltd.
Phase 2
180
Arizona, California, Colorado, Florida, Georgia, Massachusetts, Michigan, Nevada
2024-01-31
Active, closed
Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema
NCT06116916Diabetic Macular Edema (DME)
DrugsKHK4951·Aflibercept
Kyowa Kirin Co., Ltd.
Phase 2
150
Arizona, California, Colorado, Florida, Maryland, Nevada, New Jersey, New Mexico
2024-01-09
Active, closed
A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)
NCT06079879Essential Thrombocythemia
DrugsAnagrelide·Bomedemstat·Busulfan·Ruxolitinib
Merck Sharp & Dohme LLC
Phase 3
340
Arizona, California, Colorado, Massachusetts, Michigan, Nevada, New York, North Carolina
2023-12-31
Recruiting
Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
NCT05997017Endometrial Cancer, Endometrioid Tumor, Cancer, Tumor
DrugNab-sirolimus
Aadi Bioscience, Inc.
Phase 2
29
Arkansas, Florida, Nevada, New York, North Carolina, Oklahoma, Rhode Island, Texas
2023-12-28
Active, closed
REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors)
NCT05973773Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation
DrugZipalertinib
Taiho Oncology, Inc.
Phase 3
285
Nevada, Ohio, Texas
2023-12-18
Active, closed
A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Ulcerative Colitis (ROSETTA)
NCT06127043Ulcerative Colitis
DrugRosnilimab
AnaptysBio, Inc.
Phase 2
132
Arizona, California, Florida, Georgia, Illinois, Nevada, New York, Ohio
2023-12-04
Active, closed
A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis
NCT06136741Moderate to Severe Atopic Dermatitis
DrugRezpegaldesleukin
Nektar Therapeutics
Phase 2
396
Arkansas, California, Florida, Georgia, Indiana, Kentucky, Michigan, Nevada
2023-11-15
Recruiting
Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors
NCT06014658Cancer
MBrace Therapeutics
Phase 1/2
130
California, Colorado, Georgia, Illinois, Indiana, Michigan, Nevada, New Jersey
2023-11-07
Active, closed
A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development
NCT06055725Spasticity as Sequela of Stroke
Ipsen
Observational
1,057
California, Florida, Maryland, Massachusetts, Missouri, Nebraska, Nevada, North Carolina
2023-11-01
Recruiting
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
NCT05953090Atrophic Vaginitis, Vaginal Atrophy, Genitourinary Syndrome of Menopause, Lichen Sclerosus of Vulva
Stratpharma AG
Not applicable
2,000
Alabama, California, Florida, Georgia, Nevada, North Carolina, South Carolina, Tennessee
2023-10-30
Active, closed
Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration
NCT05657301Age-Related Macular Degeneration
DrugKH631
Chengdu Origen Biotechnology Co., Ltd.
Phase 1
25
Arizona, Illinois, Massachusetts, Nevada, New Jersey, Tennessee, Texas
2023-10-16
Recruiting
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
NCT05894239Metastatic Breast Cancer
DrugsPhesgo·Inavolisib
Hoffmann-La Roche
Phase 3
230
Arizona, California, District of Columbia, Maryland, Massachusetts, Michigan, Nevada, New Jersey
2023-09-08
Recruiting
Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
NCT06429280Amblyopia
Luminopia
Observational
500
California, Florida, Georgia, Hawaii, Illinois, Indiana, Nevada, New Hampshire
2023-09-01
Active, closed
Long-term Follow-up Study to Evaluate Safety and Immunogenicity of CHIKV VLP Single or Booster Vaccination
NCT06007183Chikungunya Virus Infection
Bavarian Nordic
Phase 3
715
Alabama, Arizona, Florida, Illinois, Kansas, Kentucky, Missouri, Nevada
2023-08-30
Recruiting
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
NCT05914116Advanced Solid Tumors
DrugsBNT324·Itraconazole·Abiraterone·Enzalutamide
DualityBio Inc.
Phase 1/2
862
Arizona, California, Florida, Georgia, Kentucky, Michigan, Minnesota, Nevada
2023-08-17
Active, closed
A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations
NCT05907304Advanced or Metastatic Solid Tumors
DrugsNaporafenib·Trametinib
Erasca, Inc.
Phase 1
86
California, Connecticut, Florida, Georgia, Michigan, Missouri, Nevada, Oregon
2023-08-17
Active, closed
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
NCT05797610Primary IgA Nephropathy
Hoffmann-La Roche
Phase 3
459
Alabama, California, Florida, Georgia, Idaho, Illinois, Massachusetts, Nevada
2023-08-08
Recruiting
A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.
NCT05967689Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations
DrugZipalertinib
Taiho Oncology, Inc.
Phase 2
220
Alabama, California, Massachusetts, Nevada, New Jersey, New York, Ohio, Tennessee
2023-07-31
Recruiting
Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
NCT05797831Endometrial Cancer
DrugNavtemadlin
Kartos Therapeutics, Inc.
Phase 2/3
268
California, Georgia, Illinois, Indiana, Maryland, Minnesota, Missouri, Nevada
2023-07-17
Recruiting
Prospective Study of oncRNA Stratification of Cancer by Size and Stage
NCT05833360Cancer
Exai Bio Inc.
Observational
2,400
California, Nevada
2023-07-14
Active, closed
A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus
NCT05672576Lupus Erythematosus, Systemic
DrugCenerimod
Viatris Innovation GmbH
Phase 3
451
Arizona, California, Florida, Louisiana, Nevada, New York, Texas
2023-06-26
Active, closed
A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK121-NX in Patients With Advanced Solid Tumors
NCT05627063Solid Tumor
Abbisko Therapeutics Co, Ltd
Phase 1
169
California, Michigan, Nevada, Ohio
2023-06-26
Active, closed
Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus
NCT05966480SLE
DrugEnvudeucitinib
Alumis Inc
Phase 2
408
Alabama, California, Florida, Georgia, Missouri, Nevada, New Jersey, New Mexico
2023-06-26
Active, closed
Post-Market Registry in Europe and US for the Use of VascuCelTM
NCT04906824Great Vessel Reconstruction, Peripheral Vessel Reconstruction, Suture Line Buttressing
LeMaitre Vascular
Observational
100
Idaho, Nevada, New York, North Carolina
2023-06-09
Active, closed
Evaluation of the Safety and Efficacy of Eneboparatide (AZP-3601) in Patients With Chronic Hypoparathyroidism
NCT05778071Chronic Hypoparathyroidism, Endocrine System Diseases, Parathyroid Diseases
Alexion Pharmaceuticals, Inc.
Phase 3
165
California, Colorado, Illinois, Indiana, Massachusetts, Minnesota, Nevada, New York
2023-06-07
Active, closed
iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction
NCT05870488Sacroiliac Joint Dysfunction, Sacroiliac; Fusion, Sacroiliac Disorder, Sacroiliac Joint Pain
SI-BONE, Inc.
Phase 4
110
California, Indiana, Kansas, Kentucky, Maryland, Missouri, Nevada, Oklahoma
2023-05-23
Recruiting
Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS
NCT05737121Interstitial Cystitis, Bladder Pain Syndrome
DrugsVNX001·Heparin·Lidocaine
Vaneltix Pharma, Inc.
Phase 2
120
California, Florida, Georgia, Louisiana, Massachusetts, Nevada, New York, North Carolina
2023-05-22
Active, closed
ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study
NCT05596409Metastatic Breast Cancer
DrugElacestrant
Stemline Therapeutics, Inc.
Phase 2
61
Arkansas, Illinois, Nevada, Texas
2023-05-19
Active, closed
Histological Analysis of AlloMend® Acellular Dermal Matrix Used in Breast Implant Surgeries
NCT05744414Breast Implant; Complications, Infection or Inflammation
AlloSource
Observational
30
Nevada
2023-05-17
Active, closed
A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy
NCT05707377Primary Membranous Nephropathy
DrugsTacrolimus·Zanubrutinib
BeOne Medicines
Phase 2/3
178
California, Minnesota, Nevada
2023-04-17
Recruiting
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251
NCT05626114Geographic Atrophy
DrugOpRegen
Genentech, Inc.
Phase 2
60
California, Florida, Maryland, Missouri, Nevada, North Carolina, Ohio, Pennsylvania
2023-03-23
Active, closed
A Study of HST-1011 Given as Monotherapy and in Combination With an Anti-PD1 Antibody
NCT05662397Solid Tumor, Adult, Relapsed Cancer, Refractory Cancer
DrugCemiplimab
HotSpot Therapeutics, Inc
Phase 1/2
77
Florida, Nevada, New York, Oregon, Pennsylvania, Texas
2023-03-15
Active, closed
A Study of 5 Years of Adjuvant Osimertinib in Completely Resected Epidermal Growth Factor Receptor Mutation (EGFRm) Non-small Cell Lung Carcinoma (NSCLC)
NCT05526755Stage II-IIIB Non-small Cell Lung Carcinoma
DrugsTagrisso·Osimertinib
AstraZeneca
Phase 2
188
California, Nevada, New York
2023-03-06
Recruiting
Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia
NCT05640102Waldenstrom Macroglobulinemia
DrugZanubrutinib
BeiGene
Observational
111
Alabama, California, Mississippi, Nevada
2023-03-03
Recruiting
A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer
NCT05683418HR+/HER2-negative Breast Cancer
DrugsRibociclib·Palbociclib·Fulvestrant
Totus Medicines
Phase 1
241
Illinois, Massachusetts, Nevada, Pennsylvania, Tennessee, Texas, Virginia
2023-02-15
Active, closed
Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study
NCT05797896Dry Age-related Macular Degeneration, Geographic Atrophy, Retinal Disease, Macular Degeneration
Complement Therapeutics
Observational
250
California, Indiana, Maryland, Nevada, Oregon, Pennsylvania, Texas
2023-02-07
Recruiting
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
NCT07546929Type 2 Diabetes
Housey Healthcare ULC
Phase 2
300
California, Florida, Georgia, Kansas, Louisiana, Michigan, Nebraska, Nevada
2023-02-03
Active, closed
A Feasibility Trial to Investigate the Safety and Between-group Effect Size of STIMULAN VG and Standard of Care (SoC) in Participants With Diabetic Foot Osteomyelitis
NCT05539963Diabetic Foot Osteomyelitis
Biocomposites Ltd
Phase 2
61
Arizona, Arkansas, Nevada, New Jersey, New York, North Carolina
2023-01-23
Active, closed
A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease
NCT05668013Crohn Disease, Colitis, Ulcerative
DrugDuvakitug
Teva Branded Pharmaceutical Products R&D LLC
Phase 2
247
California, Florida, Illinois, Indiana, Kansas, Kentucky, Missouri, Nevada
2023-01-11
Active, closed
Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis
NCT05588843Colitis Ulcerative
Sanofi
Phase 2
187
California, Georgia, Illinois, Missouri, Nevada, New Jersey, New York, Tennessee
2022-11-25
Recruiting
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
NCT05623020Multiple Myeloma
DrugsElranatamab·Bortezomib·Daratumumab·Lenalidomide
Pfizer
Phase 3
1,060
Florida, Nebraska, Nevada, New Jersey, New York, Texas, Utah
2022-11-10
Recruiting
Post-Market Study to Assess iTind Safety in Comparison to UroLift
NCT04757116Benign Prostatic Hyperplasia (BPH)
Olympus Corporation of the Americas
Not applicable
256
Arizona, California, Illinois, Louisiana, Minnesota, Nebraska, Nevada, New York
2022-09-26
Active, closed
MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia
NCT05464784Diabetes Mellitus, Type 2, Hypertriglyceridemia, Non-Alcoholic Fatty Liver Disease
MediciNova
Phase 2
40
Nevada, Texas
2022-08-22
Active, closed
Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes
NCT05506423Open Angle Glaucoma
Iantrek, Inc.
Observational
300
California, Florida, Georgia, Maryland, Nevada, New Jersey, New York, Pennsylvania
2022-08-17
Active, closed
Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)
NCT05607810Diabetic Macular Edema, Diabetic Retinopathy
Adverum Biotechnologies, Inc.
Observational
22
California, Nevada, Pennsylvania, Texas
2022-08-10
Active, closed
A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies
NCT05032040Ovarian Cancer, Clear Cell Carcinoma, Endometrial Cancer, Cervical Carcinoma
Xencor, Inc.
Phase 2
170
Arizona, California, Colorado, Delaware, Florida, Georgia, Michigan, Nevada
2022-07-21
Active, closed
First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors
NCT05438329Advanced Solid Tumor
DrugsDB-1305/BNT325·Pumitamig
DualityBio Inc.
Phase 1/2
1,123
Arizona, California, District of Columbia, Florida, Hawaii, Illinois, Michigan, Nevada
2022-07-19
Active, closed
Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis
NCT05126277Lupus Nephritis
DrugIanalumab
Novartis Pharmaceuticals
Phase 3
452
Alabama, California, Florida, Georgia, Louisiana, Michigan, Nevada, New York
2022-07-14
Active, closed
A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium
NCT05456425Pterygium
Cloudbreak Therapeutics, LLC
Phase 3
660
Alabama, Arizona, California, Florida, Kentucky, Nevada, South Dakota, Texas
2022-06-30
Recruiting
A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants
NCT05418868HIV Infections
DrugsPhesgo·Cabotegravir
ViiV Healthcare
Phase 1
214
Florida, Nevada, Texas
2022-06-14
Active, closed
ProVee Urethral Expander System IDE Study (ProVIDE)
NCT05186740BPH With Symptomatic Lower Urinary Tract Symptoms
ProVerum Medical
Not applicable
221
California, Florida, Illinois, Nevada, New York, North Carolina, Texas, Virginia
2022-06-09
Active, closed
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period
NCT05144256Pediatric Pyruvate Kinase Deficiency, Pediatric Hemolytic Anemia
DrugMitapivat
Agios Pharmaceuticals, Inc.
Phase 3
49
Arizona, California, Georgia, Massachusetts, Nevada, New York, Pennsylvania, Texas
2022-06-08
Active, closed
A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer
NCT05318573Advanced Urothelial Carcinoma, Advanced Non Small Cell Lung Cancer
DrugsFF-10832·Keytruda·Pembrolizumab
Fujifilm Pharmaceuticals U.S.A., Inc.
Phase 2
120
California, District of Columbia, Kansas, Kentucky, Michigan, Missouri, Nebraska, Nevada
2022-06-01
Active, closed
A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer
NCT05353257Limited-Stage Small Cell Lung Cancer
DrugsCarboplatin/cisplatin-etoposide·Slulimumab·Serplulimab
Shanghai Henlius Biotech
Phase 3
511
California, Colorado, Connecticut, Florida, Kansas, Louisiana, Minnesota, Nevada
2022-05-17
By invitation
Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With and Without Diabetic Retinopathy
NCT05296447Diabetic Retinopathy, DR
DrugsEylea·Aflibercept
AbbVie
Phase 2
100
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Jersey
2022-04-04
Active, closed
A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)
NCT05119569Relapsing Multiple Sclerosis
DrugFenebrutinib
Hoffmann-La Roche
Phase 2
109
California, Nevada
2022-03-01
Active, closed
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters
NCT05383274Urethral Stricture
Urotronic Inc.
Phase 4
34
Arkansas, Florida, Louisiana, Maryland, Nevada, New Jersey, New York, Texas
2022-02-14
Active, closed
Insignia™ Hip Stem Outcomes Study
NCT05144191Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
Stryker Orthopaedics
Not applicable
313
Arizona, California, Illinois, Nevada, New York, North Carolina, Pennsylvania, Tennessee
2022-02-07
Active, closed
Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older
NCT05304351Herpes Zoster, Shingles
DrugShingrix
Curevo Inc
Phase 2
1,516
Arizona, Florida, Illinois, Kansas, Kentucky, Nevada, Oklahoma, Tennessee
2022-02-02
Active, closed
An Efficacy and Safety Study of Basimglurant (NOE-101) in Patients With Trigeminal Neuralgia.
NCT05217628Trigeminal Neuralgia
Noema Pharma AG
Phase 2/3
166
California, Florida, Georgia, Massachusetts, Nevada, New York, Ohio
2022-01-11
By invitation
Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD
NCT05210803Neovascular Age-Related Macular Degeneration (nAMD)
DrugsLucentis·Ranibizumab
AbbVie
Phase 2
116
Arizona, California, Georgia, Maryland, Massachusetts, Minnesota, Nevada, New Mexico
2021-12-20
Active, closed
Desara ® One Single Incision Sling 522 Study
NCT04772131Stress Urinary Incontinence
Caldera Medical, Inc.
Not applicable
300
Arizona, Florida, Idaho, Indiana, Kentucky, Massachusetts, Missouri, Nevada
2021-11-01
Active, closed
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer
NCT05113251Breast Neoplasms, Breast Cancer, HER2-positive Early Breast Cancer
DrugsHerzuma·Perjeta·Herceptin·Adriamycin
AstraZeneca
Phase 3
927
Arkansas, California, Connecticut, Indiana, Kentucky, Louisiana, Minnesota, Nevada
2021-10-25
Active, closed
Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain
NCT04809376Osteoarthritis, Knee
DrugPentosan Polysulfate Sodium
Paradigm Biopharmaceuticals USA (INC)
Phase 2/3
602
Arizona, California, Florida, Illinois, Kansas, Louisiana, Nevada, South Carolina
2021-10-19
Recruiting
Helix Research Network
NCT06057181Genetic Predisposition to Disease, Genetics Disease
Helix, Inc
Observational
2,000,000
Indiana, Minnesota, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania
2021-09-13
Recruiting
Freedom-1 Study for Chronic Knee Pain
NCT03877653Osteoarthritic Knee Pain
Curonix LLC
Not applicable
100
California, Colorado, Florida, Georgia, Nevada, Ohio, Texas
2021-09-01
Active, closed
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977
NCT04862286Psoriasis
DrugsSkyrizi·Risankizumab
AbbVie
Phase 3
132
Alabama, California, Florida, Illinois, Nevada, Ohio, South Carolina, West Virginia
2021-07-24
Active, closed
da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures
NCT04403022Colorectal Cancer, Benign or Malignant Rectal or Colon Tumors
Intuitive Surgical
Not applicable
60
Florida, Michigan, Minnesota, Nevada, Pennsylvania, Texas, Washington
2021-06-03
Active, closed
FSL2 Post Approval Study for Pediatric and Young Adults Patients
NCT04959552Diabete Mellitus
Abbott Diabetes Care
Observational
550
Connecticut, Missouri, Nevada
2021-06-01
Active, closed
Atrasentan in Patients With Proteinuric Glomerular Diseases
NCT04573920IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease
DrugAtrasentan
Novartis Pharmaceuticals
Phase 2
103
California, Colorado, Louisiana, Massachusetts, Minnesota, Nevada, North Carolina, Texas
2021-03-15
Active, closed
Long-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia A
NCT04644575Hemophilia A
DrugEfanesoctocog alfa
Bioverativ, a Sanofi company
Phase 3
261
California, Florida, Georgia, Illinois, Iowa, Michigan, Nevada, New York
2021-02-23
Active, closed
Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]
NCT04645212Wet Age-related Macular Degeneration, Neovascular Age-related Macular Degeneration
Adverum Biotechnologies, Inc.
Observational
23
California, Colorado, Florida, Nevada, Pennsylvania, Tennessee, Texas
2020-12-14
Active, closed
A Study to Assess Safety and Efficacy of PRL3-Zumab in Patients With Solid Tumors
NCT04452955Solid Tumor
DrugPRL3-ZUMAB
Intra-IMMUSG Pte Ltd
Phase 2
51
Arizona, California, Kentucky, Nevada
2020-12-12
Active, closed
Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy
NCT04655976Lung Cancer, Non-Small Cell
DrugsCobolimab·Dostarlimab·Docetaxel
GlaxoSmithKline
Phase 2/3
758
California, Connecticut, District of Columbia, Hawaii, Iowa, Kentucky, Nevada, New York
2020-12-08
Active, closed
RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) With and Without Center Involved-Diabetic Macular Edema (CI-DME)
NCT04567550Diabetic Retinopathy (DR), Center-Involved Diabetic Macular Edema (CI-DME)
DrugAflibercept
AbbVie
Phase 2
139
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Jersey
2020-11-20
Active, closed
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
NCT04590963Squamous Cell Carcinoma of the Head and Neck
DrugsMonalizumab·Erbitux·Cetuximab
AstraZeneca
Phase 3
370
Arizona, Illinois, Kansas, Massachusetts, Michigan, Minnesota, Missouri, Nevada
2020-10-02
Active, closed
Study to Evaluate Loncastuximab Tesirine With Rituximab Versus Immunochemotherapy in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
NCT04384484Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma
DrugsLoncastuximab Tesirine·Rituximab·Oxaliplatin·Gemcitabine
ADC Therapeutics S.A.
Phase 3
440
California, Florida, Iowa, Kentucky, Nevada, Oregon, South Carolina, Virginia
2020-09-16
Active, closed
RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD)
NCT04514653Neovascular Age-Related Macular Degeneration (nAMD)
DrugRanibizumab
AbbVie
Phase 2
146
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Mexico
2020-08-25
Active, closed
A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer
NCT04288089Receptors, Estrogen, Genes, Erbb-2, Breast Neoplasms
Eisai Inc.
Phase 1
31
Florida, Massachusetts, Missouri, Nevada, Tennessee
2020-04-01
Active, closed
Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)
NCT04199689Papillomavirus Infections
DrugNonavalent HPV vaccine
Merck Sharp & Dohme LLC
Phase 3
6,033
California, Florida, Georgia, Idaho, Kansas, Kentucky, Missouri, Nevada
2020-02-27
Recruiting
MDR - PMCF Study for Taperloc Complete Stems
NCT04028687Hip Arthritis, Hip Disease, Hip Fractures, Hip Injuries
Zimmer Biomet
Observational
820
Nevada, Texas, Washington
2020-02-13
Active, closed
Optilume™ BPH Catheter System in Men With Symptomatic BPH
NCT04131907Benign Prostatic Hyperplasia
Urotronic Inc.
Not applicable
162
Arkansas, Colorado, Florida, Illinois, Louisiana, Maryland, Nevada, New Jersey
2020-02-05
Active, closed
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
NCT03240809Psoriasis
DrugBrodalumab
Bausch Health Americas, Inc.
Phase 4
2
California, Florida, Nevada
2020-01-24
Active, closed
Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer
NCT04114825Prostate Cancer Recurrent
RhoVac APS
Phase 2
180
Florida, Maryland, Nebraska, Nevada, New York, South Carolina, Texas
2019-11-19
Active, closed
An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis
NCT04130997Relapsing Multiple Sclerosis (RMS)
DrugUblituximab
TG Therapeutics, Inc.
Phase 3
1,100
California, Colorado, Florida, Illinois, Kansas, Michigan, Nevada, New Jersey
2019-11-18
Active, closed
Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression
NCT04180371Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer, Ovarian Cancer, Non-small Cell Lung Cancer
DrugsNuzefatide pevedotin·Opdivo·Nivolumab
BicycleTx Limited
Phase 1/2
288
California, Colorado, Florida, Michigan, Nevada, New York, Oklahoma, Pennsylvania
2019-11-07
By invitation
A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia
NCT04138927Warm Antibody Autoimmune Hemolytic Anemia
DrugFostamatinib
Rigel Pharmaceuticals
Phase 3
90
California, District of Columbia, Maryland, Massachusetts, Nevada, Washington
2019-10-30
Active, closed
COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC
NCT04068610Metastatic Microsatellite-stable Colorectal Cancer
DrugsOleclumab·Folfox·Durvalumab·Bevacizumab
MedImmune LLC
Phase 1/2
61
California, Michigan, Nevada, New York, Ohio, Rhode Island, Tennessee, Texas
2019-09-13
Active, closed
A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation
NCT04002297Mantle Cell Lymphoma; Non-Hodgkin Lymphoma
DrugsBendamustine·Zanubrutinib·Rituximab
BeOne Medicines
Phase 3
510
California, Illinois, Massachusetts, Michigan, Nevada, New York, Oregon, Pennsylvania
2019-08-20
Active, closed
A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2)
NCT04035486Non-Small Cell Lung Cancer
DrugsPemetrexed/Cisplatin·Pemetrexed/Carboplatin·Osimertinib
AstraZeneca
Phase 3
587
California, Florida, Kansas, Kentucky, Massachusetts, Nevada, New York, Ohio
2019-07-02
By invitation
Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy
NCT03999801Neovascular Age-related Macular Degeneration, Wet Macular Degeneration
AbbVie
Phase 2
865
Arizona, California, Maryland, Massachusetts, Nevada, Pennsylvania, Tennessee, Texas
2019-05-31
Recruiting
Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator
NCT03876054Chronic Pain
Abbott Medical Devices
Observational
2,000
Arizona, California, Florida, Illinois, Indiana, Minnesota, Missouri, Nevada
2019-03-13
Recruiting
Safety and Efficacy of ActiGraft Treatment in Wound Care in Medical Centers
NCT04699305Cutaneous Wounds
RedDress Ltd.
Observational
500
Nevada
2019-02-14
Recruiting
A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System
NCT05653102Knee Arthroplasty, Total
Exactech
Observational
1,000
Colorado, Florida, Nevada, Ohio, South Carolina
2019-01-23
Active, closed
Early Weight-Bearing After the Lapiplasty Procedure
NCT03740282Hallux Valgus, Bunion
Treace Medical Concepts, Inc.
Not applicable
183
Colorado, Iowa, Missouri, Nevada, Pennsylvania, Texas
2018-11-06
Active, closed
Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial Inserts
NCT03687593Total Knee Arthroplasty
Smith & Nephew, Inc.
Observational
126
Minnesota, Nevada, South Carolina, Tennessee
2018-08-26
Recruiting
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
NCT03424005Metastatic Breast Cancer
DrugsAtirmociclib·Ipatasertib·Giredestrant·Inavolisib
Hoffmann-La Roche
Phase 1/2
1,132
California, Colorado, Florida, Illinois, Minnesota, Nevada, New Jersey, New York
2018-03-30
Recruiting
Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients
NCT03695978Haemophilia A
Octapharma
Observational
200
Florida, Louisiana, Missouri, Nevada, Texas
2018-02-13
Active, closed
A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL
NCT03336333Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugsVenclyxto·Bendamustine·Venclexta·Zanubrutinib
BeiGene
Phase 3
590
Georgia, Illinois, Massachusetts, Missouri, Nevada, New Jersey, New York, North Carolina
2017-10-31
Active, closed
A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
NCT03178552Non-Small Cell Lung Cancer
DrugsCobimetinib·Divarasib·Vemurafenib·Entrectinib
Hoffmann-La Roche
Phase 2/3
1,000
California, Colorado, Florida, Kentucky, Nevada, New Hampshire, New York, Oregon
2017-09-22
Active, closed
JOURNEY II XR Safety and Effectiveness PMCF
NCT03136887Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee, Knee Osteoarthritis, Degenerative Arthritis Peripheral Joint
Smith & Nephew, Inc.
Observational
176
California, Florida, Illinois, Maryland, Michigan, Nevada, New Jersey, New York
2017-07-28
Active, closed
Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.
NCT03229200Lymphoma, B-Cell, Lymphoma, Non-Hodgkin, Leukemia, B-cell, Graft Vs Host Disease
DrugIbrutinib
Pharmacyclics Switzerland GmbH
Phase 4
297
California, Georgia, Illinois, Kentucky, Massachusetts, Michigan, Nevada, New Jersey
2017-05-22
Active, closed
INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections
NCT03037164Anemia
Cerus Corporation
Phase 3
692
Arizona, Connecticut, Florida, Georgia, Maryland, Nevada, Tennessee, Texas
2017-05-11
Active, closed
Randomized Controlled Trial of CAN-2409 Immunotherapy During Active Surveillance for Prostate Cancer (ULYSSES)
NCT02768363Prostate Cancer
DrugsAglatimagene besadenovec·Valacyclovir
Candel Therapeutics, Inc.
Phase 2
187
Colorado, Illinois, Louisiana, Maryland, Missouri, Nevada, New Jersey, New York
2016-05
Active, closed
HyaloFAST Trial for Repair of Articular Cartilage in the Knee
NCT02659215Defect of Articular Cartilage
Anika Therapeutics, Inc.
Not applicable
200
Arizona, California, Connecticut, Florida, Illinois, Louisiana, Nevada, New York
2015-12
Active, closed
A Study of Nonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast Cancer
NCT02246621Breast Cancer
DrugsAnastrozole·Abemaciclib·Letrozole
Eli Lilly and Company
Phase 3
493
Arizona, Arkansas, California, Florida, Georgia, Minnesota, Nebraska, Nevada
2014-11-06
Active, closed
A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee
NCT01542580Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity
Zimmer Biomet
Observational
255
Illinois, Nevada, Utah, Virginia
2012-03
Active, closed
Optetrak Knee System Post Market Clinical Follow-Up
NCT05788757Knee Arthroplasty, Total
Exactech
Observational
4,588
Massachusetts, Nevada, South Carolina
2011-06-01
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 6 October 2026. https://priyalifescience.com/clinical-trials-usa/state/nevada

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,118 studies in total at the last sync on 06 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 295 of those studies with a site in Nevada.

How many clinical trials are recruiting in Nevada?

150 of the 295 studies on this page are recruiting new participants as of the 06 Oct 2026, 03:16 UTC sync. A further 2 have not yet opened recruitment, 134 are active but closed to new participants, and 9 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Nevada), 295 studies
PhaseStudiesRecruitingShare
Phase 3794226.8%
Phase 2753525.4%
Not applicable381812.9%
Observational351711.9%
Phase 129179.8%
Phase 1/218106.1%
Phase 41274.1%
Phase 2/3943.1%

Most active sponsors

Lead sponsors with the most studies (Nevada)
Lead sponsorStudiesRecruiting
AbbVie114
AstraZeneca115
Merck Sharp & Dohme LLC103
Hoffmann-La Roche83
Eli Lilly and Company75
Sanofi74
Amgen51
Novartis Pharmaceuticals53
Pfizer54
GlaxoSmithKline43
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.