A Study to Evaluate the Effects of a Beef Liver Supplement on Energy, Mood, and Mental Clarity

Condition(s) studied

Investigational drug(s) / intervention(s)

Intervention: Participants receive the Ancestral Supplements Grass Fed Beef Liver supplement (Grass Fed Liver \[Bovine\], 3000 mg per serving of 6 capsules) taken once daily, with a graduated dose escalation from 1 capsule/day over the first 18 days up to the full serving of 6 capsules/day, for 12 weeks.

Placebo: Participants receive a matched placebo product (microcrystalline cellulose and natural food color) taken once daily using the same dosing regimen as the intervention arm, for 12 weeks. The taste and appearance of the placebo are matched to the test product.

Study summary

This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the Ancestral Supplements Grass Fed Beef Liver oral supplement on energy, mood, and mental clarity over 12 weeks. One hundred male and female participants aged 18-50 who report concerns regarding energy levels, mood, and mental clarity will be enrolled and randomized equally into an intervention arm (beef liver supplement) or a placebo arm.

Participants will take their assigned product once daily and complete self-reported questionnaires at Baseline, Week 4, Week 8, and Week 12. Blood testing (iron panel) will be conducted at Baseline and Week 12 at a local Quest Diagnostics Clinic. The primary objective is to evaluate the product's effects on energy and mood; the secondary objective is to assess participants' perceptions of the product's effects on energy, mood, and mental clarity, including happiness, anxiety, well-being, brain fog, and concentration.

Eligibility

Primary outcome measure(s)

• Change in Iron Status — Baseline and Week 12
  Change in blood iron levels assessed via iron panel blood test (Quest Diagnostics, iron test code 001339)
• Change in Energy Levels — Baseline, Week 4, Week 8, and Week 12
  Change in self-reported energy levels assessed via self-reported questionnaire
• Change in Mood — Baseline, Week 4, Week 8, and Week 12
  Change in self-reported mood assessed via self-reported questionnaire

Trial sites (1)

Other trials for the same condition