Clinical trial register · France

Clinical Trials in Paris, 2026

Every study on the ClinicalTrials.gov registry that lists a site in France and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 9722 matching records held by the registry are in this view. Synced 29 Oct 2026, 03:20 UTC

9722

Studies in scope

all four open statuses

6047

Recruiting now

open to new participants

1031

Lead sponsors

across recruiting studies

Top sites

Paris 604 Créteil 80 Le Kremlin-Bicêtre 48 Bordeaux 44 Bobigny 39

Trials with a site in Paris

Status

Study

Lead sponsor

Phase

Enrol

Sites in France

Start

Not yet open

Ultrasound Assessment of Joint Health in Patients With Mild Hemophilia (Factor Levels 5-40%)

NCT07719647Mild Hemophilia

Assistance Publique - Hôpitaux de Paris

Not applicable

150

Paris

2027-02

Not yet open

Evaluation of Interventions to Promote Work-Life Balance Among Students at Gaming Schools

NCT07887659Internet Gaming Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

200

Paris

2027-01-01

Not yet open

Qualitative Study of Student Financial Insecurity and Psychiatry

NCT07719816Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2027-01-01

Not yet open

Verapamil In Preclinical Type 1 Diabetes

NCT07880769Type 1 Diabetes

DrugBlood sampling

Assistance Publique - Hôpitaux de Paris

Phase 2/3

Paris

2027-01

Not yet open

Anticoagulant Cessation After Antiphospholipid Autoantibodies Loss in Thrombotic Antiphospholipid Syndrome

NCT07875153Antiphospholipid Syndrome, Thrombotic Antiphospholipid Syndrome, Thrombosis

Assistance Publique - Hôpitaux de Paris

Phase 3

234

Paris

2026-12

Not yet open

Enhancing Amoxicillin Pharmacokinetics and Pharmacodynamics Parameters With Probenecid in Bone and Joint Infections

NCT07764302Osteoarticular Infections (OAIs)

Assistance Publique - Hôpitaux de Paris

Phase 3

Chesnay, Clichy, Créteil, Paris, Tours

2026-12

Not yet open

Severe Pediatric Respiratory Syncytial Virus Infections Occurring in the Era of Antiviral Prophylaxis

NCT07893652Children <24 Months Hospitalized for RSV-related Lower Respiratory Tract Infection

Assistance Publique - Hôpitaux de Paris

Observational

300

Paris

2026-11-15

Not yet open

Diagnosis of ECMO Cannula Infection: Prospective Comparison of Sampling Methods

NCT07893639ECMO Cannula Infection, Extracorporel Membrane Oxygenation Complication

Assistance Publique - Hôpitaux de Paris

Observational

500

Paris

2026-11-01

Not yet open

Surveillance Versus Treatment of Unruptured Intracranial Aneurysms of Fortuitous Discovery

NCT07817511Unruptured Intracranial Aneurysm, Intracranial Aneurysm

Assistance Publique - Hôpitaux de Paris

Not applicable

600

Paris

2026-11

Not yet open

A Clinical Study on Systemic Sclerosis and the Validation of French-language Questionnaires Assessing Disability, Quality of Life, and Disease Status.

NCT07888842Scleroderma

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2026-11

Not yet open

Immune Responses and Pulmonary Complications After Cardiac Surgery With Cardiopulmonary Bypass

NCT07865533Cardiac Surgery Under Extra Corporeal Circulation

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-11

Not yet open

Obinutuzumab in Systemic Sclerosis

NCT07842523Systemic Sclerosis in Adults

DrugObinutuzumab

Assistance Publique - Hôpitaux de Paris

Phase 2

120

Paris

2026-11

Not yet open

The Microbiome in Uveitis and Pediatric Inflammatory Diseases

NCT07885501Noninfectious Uveitis

Assistance Publique - Hôpitaux de Paris

Observational

500

Paris

2026-11

Not yet open

Virtual Human Twins as Tools for Personalized Clinical Care in Heart Failure With Preserved Ejection Fraction: a Pilot Study

NCT07902453Heart Failure

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-11

Not yet open

Description of Clinicians' Predictive Abilities Before and After a Diffusion Tensor Imaging (DTI)

NCT07863414Diffusion Tensor Imaging Prognosis, Brain Injury, Traumatic

Assistance Publique - Hôpitaux de Paris

Observational

220

Marseille, Paris

2026-11

Not yet open

KetAmine and Recovery After Mechanical VentilAtion ( KARMA )

NCT07590687Critical Illness

Assistance Publique - Hôpitaux de Paris

Phase 3

640

Paris

2026-10-19

Not yet open

Early Addiction Care Pathway After Acute Drug Intoxication in Emergency Departments

NCT07738835Intoxication; Opioid

Assistance Publique - Hôpitaux de Paris

Not applicable

266

Paris

2026-10-15

Recruiting

Comparison of Cardiac Index Measurement Using Right Ventricular Pressure Curve Analysis and Thermodilution Via a Swan-Ganz IQ™ Catheter.

NCT07628023Septic Shock

Assistance Publique - Hôpitaux de Paris

Observational

Angers, Paris

2026-10-15

Recruiting

Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's Disease

NCT07505394Parkinson Disease, Impulse Control Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

528

Paris

2026-10-13

Not yet open

Sexual Quality of Life in Female Patients With Lipodystrophy Syndromes or Turner's Syndrome: a Case-control Study

NCT07799012Lipodystrophy Congenital Generalized, Lipodystrophy, Familial Partial, Turner Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

1,416

Paris

2026-10-01

Not yet open

Use of Low Doses of Interleukin-2 in Autism Spectrum Disorders

NCT07589842Autism Spectrum Disorder

DrugsIL2·NaCl

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-10-01

Not yet open

ADHD and Mental Effort

NCT07812714ADHD

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-10-01

Not yet open

Mentalization and Social Cognition in Adolescents After Suicide Attempt

NCT07688798Violent Suicide Attempts in Adolescents

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-10

Not yet open

Interventional rTMS for Improving Social Perception in Autism

NCT07828457Autism Spectrum Disorders (ASD)

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-10

Not yet open

Assessment of Dietary Balance in Home-Dwelling Patients With Stage 4 and 5 Chronic Kidney Disease Using URIKI (IKI), a Connected Urine Test Strip and In Vitro Diagnostic Medical Device

NCT07746037Chronic Kidney Disease (CKD)

Assistance Publique - Hôpitaux de Paris

Not applicable

450

Paris

2026-10

Not yet open

Impact of Dietary Intervention Within an Interprofessional Cooperative Protocol for Prandial Insulin Dose Adjustment in People Living With Type 1 Diabetes

NCT07846852Diabetes Mellitus, Type 1

Assistance Publique - Hôpitaux de Paris

Observational

163

Paris

2026-10

Not yet open

Sildenafil Plus Hypothermia to Treat Neonatal Encephalopathy

NCT06810284Hypoxic-Ischemic Encephalopathy

DrugSildenafil

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-10

Not yet open

Sensor-Based Optimization of Therapy for Parkinson's Disease Patients With Motor Fluctuations

NCT07074119Parkinson Disease (PD)

Assistance Publique - Hôpitaux de Paris

Not applicable

218

Paris

2026-10

Not yet open

Cryptococcosis Associated With Bruton Tyrosine Kinase Inhibitors

NCT07881055Cryptococcosis

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-10

Not yet open

Rituximab vs Placebo for Maintenance in Systemic Sclerosis - Interstitial Lung Disease

NCT07827742Systemic Sclerosis in Adults

DrugRituximab

Assistance Publique - Hôpitaux de Paris

Phase 2

120

Paris

2026-10

Not yet open

Patient Choice Between Antibiotics and Appendectomy in Uncomplicated Appendicitis (FRENCH 47 - ALACARTE)

NCT07857252Acute Appendicitis

DrugAmoxicillin-clavulanate

Assistance Publique - Hôpitaux de Paris

Phase 2

560

Paris

2026-10

Not yet open

Clinical and MRI Characteristics of Delayed Onset Muscle Soreness (DOMS) of the Shoulder Rotator Muscles Induced by Eccentric Exercise: An Exploratory Prospective Experimental Study

NCT07880782Delayed Onset Muscle Soreness Experimentally Induced

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-10

Not yet open

Use of Connected Glasses to Help the Communication of Non Temporarily Speaking Patients in Intensive Care Unit : a Pilot Study

NCT07776795Mechanical Ventilation, Critical Care, Intensive Care, Artificial Respiration, Communication Aids

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-10

Recruiting

Long-term Psychological and Cognitive Evaluation of Children Treated With Allogeneic Hematopoietic Stem Cell Transplantation for Immunodeficiency

NCT07766304Primary Immunodeficiencies, ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-09-19

Recruiting

Decoding Central Defects in Dystrophinopathies From Diagnostic to Remediation

NCT07125898Dystrophinopathies

Assistance Publique - Hôpitaux de Paris

Observational

110

Paris

2026-09-16

Not yet open

Creative Processes and Children With a Neurodeveloppement Disorder

NCT07803146Neurodevelopmental Disorders (NDD)

Assistance Publique - Hôpitaux de Paris

Observational

212

Paris

2026-09-15

Recruiting

Feasibility of the Application of a New Six-month Treatment for Multidrug-resistant Tuberculosis (MDR-TB) Patients in France (FAST-MDR)

NCT07486024MDR-TB, Tuberculosis Multi Drug Resistant Active, Antibiotic Resistance, Mycobacterium Tuberculosis

DrugBedaquiline

Assistance Publique - Hôpitaux de Paris

Phase 3

Amiens, Paris, Rennes, Toulouse

2026-09-11

Recruiting

Evaluation of Cochlear Implantation in Unilateral or Asymmetric Hearing Loss in Children.

NCT06930170Unilateral Hearing Loss, Asymmetric Hearing Loss

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-09-03

Not yet open

Obinutuzumab for Systemic Lupus Erythematosus Pure Membranous Nephropathy: a Phase II Trial

NCT07721363Lupus Nephritis, Membranous Nephropathy

DrugObinutuzumab

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-09-02

Not yet open

Evaluation of the Benefits of Hypnosis in Improving the Quality of Life of Patients With Chronic Obstructive Pulmonary Disease (COPD) Suffering From Persistent Dyspnea

NCT07637604Chronic Obstructive Pulmonary Disease (COPD), Dyspnea

Assistance Publique - Hôpitaux de Paris

Not applicable

154

Paris

2026-09-01

Not yet open

Assessment of Healthcare Professionals' Preparedness to Screen for and Manage Women Experiencing Intimate Partner Violence During the Perinatal Period

NCT07818096Intimate Partner Violence

Assistance Publique - Hôpitaux de Paris

Observational

1,000

Paris

2026-09

Not yet open

Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome Application in Patients With IDH-mutated Glioma

NCT07439302Oncology, Glioma

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-09

Not yet open

Evaluation of Circadian Hormonal Balance: LC-MS/MS Measurement of Salivary and Serum Steroids in Patients With Congenital Adrenal Hyperplasia

NCT07718230Congenital Adrenal Hyperplasia, Adrenal Insufficiency, Hyperandrogenism; 21-hydroxylase Deficiency

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-09

Not yet open

Topical Clobetasol Propionate for Inflammatory Hand Osteoarthritis

NCT07812701Hand Osteoarthritis

Assistance Publique - Hôpitaux de Paris

Phase 2

187

Paris

2026-09

Not yet open

Study of Filovirus Disease Morbi-mortality

NCT07821580Filovirus Disease

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-09

Not yet open

Personalized and Automated Digital Coaching in People With Non-specific Chronic Low Back Pain

NCT06498271Chronic Low Back Pain

Assistance Publique - Hôpitaux de Paris

Not applicable

330

Paris

2026-09

Not yet open

Self-training and Resuscitation Techniques: Evaluation of the Performance and Impact on the Quality of Cardiopulmonary Resuscitation (CPR)

NCT07820605Cardiac Arrest (CA)

Assistance Publique - Hôpitaux de Paris

Observational

265

Paris

2026-09

Not yet open

Standard of Care Comparative Arm of Phase 1/2 Gene Therapy Trial DREPAMIR" in Severe Sickle Cell Disease Patients

NCT07752043Sickle Cell Disease (SCD), Vaso-occlusive Events

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-09

Not yet open

Study Evaluating a Gene Therapy for IPEX Syndrome Through the Expression of FOXP3 on Deficient T Cells to Produce Tregs-like.

NCT07697118The Immune Dysregulation Polyendocrinopathy Enteropathy X-linked Syndrome is a Primary Immunodeficiency Caused by Pathogenic Variants in Forkhead Box Protein 3

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Paris

2026-09

Not yet open

Efficacy of Temocillin Compared to Standard of Care in the Treatment of Neisseria Gonorrhoeae Infections

NCT07631364Neisseria Gonorrhoeae (Ng) Infections

DrugCeftriaxone

Assistance Publique - Hôpitaux de Paris

Phase 3

360

Paris

2026-09

Not yet open

Spinal Bracing in Adults With Painful Degenerative Scoliosis: a Randomized Controlled Open Trial

NCT06774898Degenerative Scoliosis, Scoliosis Idiopathic, Thoracolumbar Scoliosis

Assistance Publique - Hôpitaux de Paris

Phase 3

130

Paris

2026-09

Not yet open

Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study

NCT07760636Cardiac Arrest (CA), Intensive Care Unit (ICU) Admission, Return of Spontaneous Circulation, Comatose

Assistance Publique - Hôpitaux de Paris

Observational

270

Paris

2026-09

Not yet open

Hospital and Extra-hospital Nursing Care for Tuberculosis

NCT06696053Tuberculosis

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-09

Not yet open

Value of Biomarkers of Brain Injury for Predicting Psycho-cognitive Sequelae Secondary to Sepsis: a Prospective Multicenter Study

NCT07746050Sepsis, Septic Shock

Assistance Publique - Hôpitaux de Paris

Not applicable

210

Paris

2026-09

Not yet open

Parallel Sequencing of Fetal Genome and RNA in the Presence of Ultrasound Warning Signs: a Complementary Approach for the Prenatal Diagnosis of Rare Diseases.

NCT07790536Couples Eligible for Prenatal Exome Sequencing

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-09

Recruiting

4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in Cirrhosis

NCT07554183Cirrhosis, Portal Hypertension

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-08-25

Recruiting

A Comparative Study of Fusional Vergence According to Ocular Dominance in Healthy Subjects

NCT07697131No Eye Disorder

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-08-20

Recruiting

" Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation "

NCT06602557Pneumonia, Bacterial, Extracorporeal Membrane Oxygenation

DrugAmikacin

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-08-10

Not yet open

Suivi Prospectif Des ostéomyélites de la Base du crâne

NCT07665866Malignant External Otitis (Necrotizing/Malignant Otitis Externa), Central Skull Base Osteomyelitis

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-08-01

Not yet open

Long-term Evaluation of Quality of Life and Aesthetic Outcomes After Autologous Breast Reconstruction Using the Profunda Artery Perforator (PAP) Flap

NCT07728565Breast Cancer, Acquired Absence of Breast, Autologous Breast Reconstruction

Assistance Publique - Hôpitaux de Paris

Observational

264

Paris

2026-08-01

Recruiting

Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)

NCT07412028Polycystic Ovary Syndrome, Familial Partial Lipodystrophy, LMNA (LaMin Nuclear A) Related Disorders

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-07-21

Not yet open

Does Erectile Dysfonction Allow to Evaluate Subendocardial Viability Among Treated Patients With Hypertension ?

NCT07719790Hypertension, Erectile Dysfunction

Assistance Publique - Hôpitaux de Paris

Observational

120

Paris

2026-07-17

Not yet open

Pediatric Von Hippel-Lindau Disease: Natural History, Predictive Factors, and Long-Term Functional Outcomes of Central Nervous System Hemangioblastomas

NCT07705529Von Hippel-Lindau Disease, Central Nervous System Hemangioblastoma

Assistance Publique - Hôpitaux de Paris

Observational

Lille, Lyon, Paris

2026-07-15

Recruiting

Therapeutic Approach of Repeated Transient Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis.

NCT07571486Amyotrophic Lateral Sclerosis, Charcot Disease

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Paris

2026-07-15

Recruiting

Direct Extubation Versus Extubation After a Spontaneous Breathing Trial in Patients at Low Risk of Extubation Failure

NCT07019636Weaning From Mechanical Ventilation, Extubation

Assistance Publique - Hôpitaux de Paris

Not applicable

314

Paris

2026-07-15

Recruiting

Breast Cancer Risk Assessment in Night Shift Workers - Implementation of a Personalized Consultation

NCT07630935Breast Neoplasms Diagnosis

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-07-08

Recruiting

LEOPARD Prospective Validation Cohort 1

NCT06723275Decompensated Liver Cirrhosis, Primary Biliary Cholangitis, Primary Sclerosing Cholangitis, Hepato-cellular Carcinoma

Assistance Publique - Hôpitaux de Paris

Observational

630

Clichy, Créteil, Montpellier, Paris

2026-07-07

Not yet open

Oral Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis

NCT05202990Pediatric Ulcerative Colitis in Remission

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-07-01

Not yet open

Effect of a Weekly Yoga Program Integrated Into Standard Care on Disease Activity, Fatigue, Mood, and Treatment Adherence in Patients With Systemic Autoimmune and Inflammatory Diseases: A Prospective Observational Study

NCT07685288Auto Immune Disease, Auto-inflammatory Disease

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-07

Not yet open

EFFECT OF PLATELET CONCENTRATE TRANSFUSION ON MICROCIRCULATORY ENDOTHELIAL FUNCTION IN INTENSIVE CARE UNIT

NCT07682246Thrombocytopenia, Prophylactic Platelet Transfusion, Platelet Transfusion, Endothelial Function

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-07

Not yet open

Quality of Life of Caregivers Supporting an Older Adult With Cancer

NCT07704073Caregiver Quality of Life, Geriatric Oncology, Geriatric Medicine

Assistance Publique - Hôpitaux de Paris

Observational

116

Paris

2026-07

Not yet open

Assessment of the Reproducibility of the Recruitment-to-inflation Ratio (R/I Ratio) Measurement in Patients With Acute Respiratory Distress Syndrome

NCT07666503Acute Respiratory Distress Syndrome (ARDS)

Assistance Publique - Hôpitaux de Paris

Observational

Créteil, Le Kremlin-Bicêtre, Paris

2026-06-30

Recruiting

Real-life Evaluation of Endopredict® in Early HR+/HER2- Breast Cancer

NCT07379918Breast Cancer (Early Breast Cancer), Breast Cancer Survivors, Breast Cancer Prognostic, Early Hormone Receptor-positive (HR-positive)

Assistance Publique - Hôpitaux de Paris

Observational

1,000

Paris

2026-06-28

Recruiting

Combined Gastrointestinal Decontamination in Acute Severe Poisoning

NCT07201311Severe Poisoning With Cardiotropic or Psychotropic Drug, Admission to Intensive Care

Assistance Publique - Hôpitaux de Paris

Phase 2

200

Paris

2026-06-24

Recruiting

"Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)"

NCT07427472Heterozygous Familial Hypercholesterolemia (HeFH)

Assistance Publique - Hôpitaux de Paris

Not applicable

300

Paris

2026-06-19

Recruiting

Signature Response to Light Therapy in Unipolar and Bipolar Major Depressive Episode (MDE)

NCT07462637Major Depressive Episode

Assistance Publique - Hôpitaux de Paris

Not applicable

173

Paris

2026-06-17

Recruiting

Feasibility and Reliability of Integrating Electrically Evoked Stapedius Reflex Threshold (eSRT) Measurement in a Pediatric Cochlear Implant Programming Center

NCT07417956Hearing Loss in Children With Unilateral or Bilateral Cochlear Implants

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-06-15

Recruiting

Evaluation of a Therapeutic Education Program on Self-image in Patients With Chronic Inflammatory Rheumatic Diseases

NCT07170826Chronic Inflammatory Rheumatic Diseases

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-06-12

Recruiting

Mapping the Healthcare Pathway to Multidisciplinary Assessment of 12-25 Year Olds With Somatic Symptom Disorder

NCT06582173Somatic Symptoms, Medically Unexplained Symptoms, Somatoform Disorders

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-06-10

Recruiting

Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative Colitis

NCT06228352Ulcerative Colitis

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-06-09

Recruiting

Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure

NCT07047092Chronic Obstructive Pulmonary Disease Exacerbation, Obstructive Sleep Apnea Exacerbation

Assistance Publique - Hôpitaux de Paris

Phase 3

386

Paris

2026-06-03

Recruiting

Translation and Cross-Cultural Adaptation Into French of the COMFORTneo Pain Assessment Tool for Newborns

NCT07463170Pain

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-06-02

Recruiting

"Translating Articular Biomarkers Into Diagnoses"

NCT06312943Inflammatory and Non-inflammatory Bone and Joint Diseases

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-06-02

Recruiting

Primitive Immunodeficiency, Intrauterine Devices and Menstrual Hygiene Products

NCT06519734Primary Immune Deficiency Diseases

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2026-06-01

Not yet open

Fertility and Polycystic Ovary Syndrome

NCT07499518Polycystic Ovary Syndrome (PCOS)

Assistance Publique - Hôpitaux de Paris

Observational

473

Paris

2026-06-01

Not yet open

Performance of Clinical Metagenomics in Stool and Urine Samples for Unexplained Diseases Diagnostic and Emerging Diseases Surveillance in Immunocompromised Patients

NCT07603453Primary or Secondary Immune Deficiency Including Immunosuppressive Therapy, Chemotherapy, HIV Infection

Assistance Publique - Hôpitaux de Paris

Observational

120

Paris

2026-06-01

Not yet open

Efficacy of Text-messaging on Activity Limitation in People With Chronic Low Back

NCT06903091Chronic Non-specific Low Back Pain

Assistance Publique - Hôpitaux de Paris

Not applicable

100

Paris

2026-06-01

Recruiting

Direct Oral Challenges in Private Practice Setting to Delabeling Children With Beta-lactam Allergy

NCT07002814Allergy

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2026-06

Not yet open

Bosentan in the Treatment of Giant Cell Arteritis

NCT06957002Giant Cell Arteritis (GCA)

DrugBosentan

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-06

Not yet open

Electrophysiological Analysis of Gamma-Hydroxybutyrate-induced Sleep in Intensive Care Patients

NCT07596342Sleep Disorder (Disorder), Critical Care

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-06

Not yet open

Denys-Drash Syndrome and Risk of Post-transplant Lymphoproliferative Disorder

NCT07605884Denys-Drash Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

108

Bron, Lille, Montpellier, Nancy, Nantes, Paris

2026-06

Not yet open

Prediction of Labor Induction Outcome in Nulliparous Women

NCT07637318Nulliparous Patient With Unfavourable Cervix, Undergoing Labor Induction at Term ≥ 39SA

Assistance Publique - Hôpitaux de Paris

Observational

190

Paris

2026-06

Not yet open

Reduced Post-transplant Cyclophosphamide Dose in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation for Hematological Malignancies

NCT07193420GVHD - Graft-Versus-Host Disease, HSCT, Haploidentical Stem Cell Transplantation

DrugCyclophosphamide

Assistance Publique - Hôpitaux de Paris

Phase 3

180

Paris

2026-06

Recruiting

Study of Skin and Gut Microbiome in a Skin Condition Involving Skin Barrier Impairment and Allergic Symptoms: Netherton Syndrome

NCT07280091Netherton Syndrome

DrugsSaliva samples·Stool samples·Blood samples

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-05-26

Active, closed

Natural History of Andes Virus Infection

NCT07703579Andes Hantavirus

Assistance Publique - Hôpitaux de Paris

Observational

Bordeaux, Paris

2026-05-19

Recruiting

Implementing Low-dose ct Lung Cancer Screening in France.

NCT07513818Lung Cancer

Assistance Publique - Hôpitaux de Paris

Not applicable

20,000

Lyon, Paris

2026-05-11

Recruiting

Study of the Immunological Pathophysiological Mechanisms Associated With Acute Respiratory Distress Syndrome

NCT07395076Acute Respiratory Distress Syndrome (ARDS)

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-05-11

Recruiting

Virus-associated Tumour Microenvironment

NCT06471296Lymphoma, Cancers of the Lung, Cancer Anal Canal

Assistance Publique - Hôpitaux de Paris

Observational

150

Paris

2026-05-05

Not yet open

Hormonal and Microbiota Modulation After Endoscopic Sleeve Gastroplasty

NCT07576777Obesity (Disorder), Metabolic Disorders

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-05-04

Not yet open

Evaluation of a New Strategy to Approach the Transgender Sex Worker Populations and Their Clients for Access to a Preventive Sexual Health System Through the ORTIF Digital Teleconsultation Solution

NCT07516691HIV

Assistance Publique - Hôpitaux de Paris

Observational

250

Paris

2026-05-01

Recruiting

Benchmarking Large Language Models Against Tumour Boards for Oncology Treatment Recommendations

NCT07739121Breast Neoplasms, Lung Neoplasms, Urologic Neoplasms, Prostatic Neoplasms

Assistance Publique - Hôpitaux de Paris

Observational

100

Boulogne-Billancourt, Paris

2026-05-01

Not yet open

Exploring the Physiological Mechanisms of Austism Through Organoids

NCT07494331Autism Spectrum Disorder (ASD

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-05-01

Not yet open

Long-term Follow-up of Diabetic Patients From the GLUTADIAB Study

NCT07347613Diabetes

DrugBlood sampling

Assistance Publique - Hôpitaux de Paris

Observational

450

Paris

2026-05-01

Not yet open

Fecal Microbiota Transplantation for Primary Sclerosing Cholangitis - Randomized Study Versus Sham Transplantation

NCT07477782Primary Sclerosing Cholangitis (PSC), Inflammatory Bowel Disease (IBD)

DrugFecal Microbiota Transplantation

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-05

Not yet open

Efficacy of Cannabidiol in the Management of Self-injuries in Children and Adolescents With Severe Neurodevelopmental Disorders.

NCT07564245Neurodevelopmental Disorders With Severe Self-injuries

DrugCannabidiol

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-05

Not yet open

Safety and Efficacy of Gene Therapy of FHL Type 3 Caused by Mutations in the Human UNC13D Gene by Transplantation of a Single Dose of Autologous CD34+ Cells Transduced ex Vivo With the UNC13D LV Vector Expressing the UNC13D cDNA

NCT06736080Familial Hemophagocytic Lymphohistiocytosis Type 3 (FHL 3)

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Paris

2026-05

Not yet open

Translational Potential of ex Vivo Gene Therapy in GM2 Gangliosidosis

NCT07445490Tay-Sachs Disease Ganglioside, Sandhoff Disease Ganglioside

DrugBlood sample

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-05

Not yet open

Prevention of Postoperative Respiratory Complications

NCT06899295General Anesthesia, Ventilator-Induced Lung Injuries, Postoperative Respiratory Complications

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-05

Recruiting

Cognition and Patients With Lung Cancer

NCT07160751Localized, Operable Non-small Cell Lung Cancer

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-04-24

Recruiting

Study of Cell-free DNA in Children and Adolescents With Acute Lymphoblastic Leukemia

NCT07483476Acute Lymphoblastic Leukemia ALL

Assistance Publique - Hôpitaux de Paris

Observational

205

Paris

2026-04-24

Recruiting

Brain-lung Interaction During Acute Respiratory Failure

NCT07279831Acute Respiratory Failure

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-04-22

Recruiting

Language Development in Children With Cochlear Implants and Speech-language Therapy Interventions

NCT07447427Severe to Profound Prelingual Hearing Loss

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-04-17

Not yet open

Hospital Effluents: a Health Monitoring Tool in the Era of Multi-resistance

NCT07499505Multidrug-resistant Organisms (MDROs)

Assistance Publique - Hôpitaux de Paris

Observational

150

Paris

2026-04-15

Not yet open

Picture Naming Decoding From Intraoperative Recordings

NCT07499479Brain Tumor Adult

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-04-15

Recruiting

Comprehensive Biopsychosocial Approach for Acute Low Back Pain Management in the Emergency Department: a Stepped-wedge Cluster-randomized Clinical Trial

NCT07375914Non-traumatic Low Back Pain

Assistance Publique - Hôpitaux de Paris

Not applicable

782

Paris

2026-04-14

Recruiting

HEalthCAre Workers' Health: a Transversal Evaluation

NCT06588621Occupational Health

Assistance Publique - Hôpitaux de Paris

Observational

2,000

Paris

2026-04-13

Recruiting

Autoimmune Neurological Diseases and Those Secondary to Immunotherapy: Study of Immunological Mechanisms and Research Into Targets of Immune Attack

NCT07456358Neurological Diseases, Auto Immune Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

160

Le Kremlin-Bicêtre, Paris

2026-04-09

Recruiting

Characterization of Social Cognition Profiles in Children and Adolescents With Neurodevelopmental Disorders: a Clinical Study Using a Multidimensional Battery

NCT07439276Neurodevelopmental Disorders, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Atypical Neurodevelopmental Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

100

Paris

2026-04-08

Recruiting

Evaluation of Fibroscan® Performance in Diagnosing Acute Heart Failure in Patients Presenting to the Emergency Department

NCT07449377Acute Heart Failure (AHF)

Assistance Publique - Hôpitaux de Paris

Not applicable

100

Paris

2026-04-02

Not yet open

Sports Shoes and the Six-Minute Walk Test in COPD

NCT07445750Chronic Obstructive Pulmonary Disease (COPD), Dyspnoea, Exercise Intolerance

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-04-01

Not yet open

Effect of Aspirin and Folic Acid for Sudden Sensorineural Hearing Loss

NCT07113158Sudden Sensorineural Hearing Loss

DrugAspirin

Assistance Publique - Hôpitaux de Paris

Phase 3

142

Paris

2026-04-01

Not yet open

Impact of Androgen Signaling on the Composition of the Immune Microenvironment in Glioblastomas

NCT07472387Glioblastoma (GBM)

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-04-01

Not yet open

Quantitative 3D UltraSound Brain Imaging: Development of New Bedside Biomarkers to Better Predict Neurodevelopmental Outcomes in Preterm Infants

NCT07358819Very Preterm Infants Born < 30 Weeks of Gestation

Assistance Publique - Hôpitaux de Paris

Not applicable

360

Paris

2026-04

Not yet open

Virtual Twins as Tools for Personalized Clinical Care in Renal Denervation - Pilot Study

NCT07462572Hypertension

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-04

Not yet open

OSIA System Bilateral Implantation Efficacy Evaluation in Children With Ear Aplasia

NCT07358728Deafness Caused by High Grade Microtia or Ear Atresia

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-04

Not yet open

Tocilizumab in Chronic Inflammatory CPPD Disease

NCT07254637Calcium Pyrophosphate Deposition Disease

DrugTocilizumab

Assistance Publique - Hôpitaux de Paris

Phase 2

Lomme, Paris, Corbeil-Essonnes, Dijon, Nantes, Rennes, Saint-Etienne

2026-04

Not yet open

Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss

NCT07265505Recurrent Implantation Failure, Recurrent Pregnancy Loss, Infertility, Female, Endometrial Diseases

Assistance Publique - Hôpitaux de Paris

Not applicable

100

Paris

2026-04

Not yet open

Clonal Hematopoiesis of Immunological Significance

NCT05969821Immune System Diseases, Autoimmune Diseases, Inflammation, Autoinflammatory Diseases

Assistance Publique - Hôpitaux de Paris

Observational

5,000

Paris

2026-04

Not yet open

A Study of Multilocus Methylation Abnormalities in Subjects With Imprinting Disorders

NCT07497477Imprinting Disorder, MLID, Multi-locus Imprinting Disturbance, Differentially Methylated Regions

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-04

Recruiting

Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases

NCT07531732Frontotemporal Dementia, Behavioral Variant, Alzheimer Disease

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-04

Recruiting

Validation of TRansanal Irrigation Adherence scaLe (TRIAL)

NCT06805903Irritation; Anus

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-03-30

Recruiting

Health Economic Evaluation of Non-Invasive Prenatal Exclusion Diagnosis

NCT07469657Monogenic Diseases, Genetic Diseases, Inborn

Assistance Publique - Hôpitaux de Paris

Observational

300

Paris

2026-03-26

Recruiting

Longitudinal Study of Gene Expression in the Human Placenta During First-trimester and Full-term Pregnancy at the Single Cell Level

NCT06427408Pregnancy Related

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-03-25

Recruiting

Quality of Life After Billroth II or Roux-en-Y for Gastric Cancer

NCT06768164Gastric (Cardia, Body) Cancer

Assistance Publique - Hôpitaux de Paris

Phase 3

250

Paris

2026-03-20

Recruiting

How to Develop the Highest Possible Leading-edge Interdisciplinary Care Model for People With MS, That Will be Relevant to All Stakeholders and Declinable to Different Local Contexts With the Ultimate Goal of Ensuring the Highest Level of Quality of Care in MS.

NCT07289724Multiple Sclerosis

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-03-18

Recruiting

Improving Patients' Adherence to Their Chronic Treatments by Implementing a Simple, Standardized and Redundant Message Delivered by Healthcare Professionals.

NCT06748118Chronic Disease, Therapeutic Adherence, Training Group, Sensitivity, Delivery Simple, Standardized & Redundant Message to Patient

Assistance Publique - Hôpitaux de Paris

Not applicable

1,210

Angers, Antibes, Issy-les-Moulineaux, Marseille, Nantes, Paris, Toulouse, Tours

2026-03-18

Recruiting

Parenting and CAH - 21-hydroxylase Deficiency

NCT06900153CAH - 21-Hydroxylase Deficiency

Assistance Publique - Hôpitaux de Paris

Observational

200

Bordeaux, Bron, Créteil, Le Kremlin-Bicêtre, Paris

2026-03-16

Not yet open

EEG Signal Correlates During Anesthesia and Sedation in Adults and Children

NCT07460414Anesthesia, Sedation, Consciousness Monitors

Assistance Publique - Hôpitaux de Paris

Observational

330

Paris, Colombes

2026-03-15

Recruiting

Early Preventive Left Ventricle Unloading After VA-ECMO for Refractory Cardiogenic Shock

NCT07027202Cardiogenic Shock Acute

Assistance Publique - Hôpitaux de Paris

Not applicable

298

Clermont-Ferrand, Créteil, Lille, Paris, Rennes, Strasbourg, Toulouse, Vandœuvre-lès-Nancy

2026-03-13

Recruiting

Peripheral and Intrarenal B Cell Study in Antibody Mediated Transplant Rejection : Phenotypic and Transcriptional Study, Study of Reactivity

NCT07134491Antibody Mediated Rejection After Kidney Transplantation

DrugBlood collection

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-03-13

Not yet open

Functional Restoration for Chronic Low Back Pain: Medico-economic Impact

NCT07472374Nonspecific Chronic Low Back Pain With Work Disability

Assistance Publique - Hôpitaux de Paris

Phase 3

242

Paris

2026-03-10

Recruiting

Host-microbiota Interactions in Auto-inflammatory Diseases

NCT07718555Autoinflammatory Diseases

Assistance Publique - Hôpitaux de Paris

Observational

300

Paris

2026-03-09

Not yet open

Study of the Lived Experience of Patients With Prosthetic Joint Infection, Their Families, and Healthcare Professionals. Development of a Therapeutic Education Program for Patient Care (TEP).

NCT07409402Prosthetic Joint Infection

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-03-02

Not yet open

Preclinical Development of a 3D Bili-MRI Reconstruction Tool and an Artificial Intelligence Algorithm to Assist Endoscopists in Performing Endoscopic Retrograde Cholangiopancreatography (ERCP)

NCT07401485Patients With Biliary Stricture Treated During ERCP With Available MRCP and Abdominal CT Scan

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-03-02

Not yet open

Identification of Early Biomarkers of Pre-school ADHD

NCT07440992ADHD

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-03-01

Not yet open

Reliability of Transcutaneous Bilirubin Measurement According to the Skin Colour of Newborns

NCT07315126Neonatal Jaundice

Assistance Publique - Hôpitaux de Paris

Observational

510

Paris

2026-03

Not yet open

Regional Ventilation Evaluation During Neuro-injury Weaning Study

NCT07067671Acute Brain Injury, Mechanical Ventilation, Prolonged Weaning, Traumatic Brain Injury

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-03

Not yet open

Long-term Use of Intrapulmonary Percussive Ventilation for Preventing Hospitalizations Due to Respiratory Decompensation in Children With Multiple Disabilities

NCT07473856Respiratory Decompensation, Multiple Disabilities

Assistance Publique - Hôpitaux de Paris

Not applicable

146

Paris

2026-03

Not yet open

Efficacy of a Self-Management Smartphone App to Improve Safety Skills in Patients With Inflammatory Arthritis

NCT07460739Rhumatoid Arthisis, Spondyloarthritis (SA), Psoriatic Arthritis (PsA)

Assistance Publique - Hôpitaux de Paris

Not applicable

144

Paris

2026-03

Recruiting

Characterization and Contribution of Genome-wide DNA Methylation (DNA Methylation Episignatures) in Rare Diseases With Prenatal Onset

NCT06475651Rare Fetal Genetic Diseases, Congenital Malformation

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-02-26

Recruiting

Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA.

NCT07432867Sickle Cell Disease

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Paris

2026-02-25

Recruiting

Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo

NCT06694740Post-aggressive Immunosuppression, Adult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6, Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C

DrugInterferon Gamma 1-b

Assistance Publique - Hôpitaux de Paris

Phase 2/3

170

Paris

2026-02-24

Recruiting

Evaluation of Therapeutic Adherence Among Patients Followed in the Department of Hereditary Metabolic Diseases at Necker Hospital

NCT07356557Metabolic Diseases

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2026-02-23

Recruiting

Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients

NCT07308171Ventilated Patients

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-02-17

Recruiting

Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.

NCT06949579High Myopia

Assistance Publique - Hôpitaux de Paris

Not applicable

200

Paris

2026-02-12

Recruiting

New Therapeutic Strategy Against Preeclampsia

NCT06464159Preeclampsia

DrugBiological collection

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-02-10

Not yet open

Biological Collection for the Purpose of Exploring Genetic and Clinical-biological Factors Associated With Variability in Response to Mavacamten in the Treatment of Obstructive Hypertrophic Cardiomyopathy

NCT07439952Obstructive Hypertrophic Cardiomyopathy (oHCM)

Assistance Publique - Hôpitaux de Paris

Observational

300

Boulogne-Billancourt, Le Kremlin-Bicêtre, Paris

2026-02-05

Recruiting

Social-cognitive Functioning: Validation of a New Neuropsychological Test

NCT05558709Alzheimer's Disease (AD), Lewy Body Dementia (LBD), Frontotemporal Degeneration (FTD)

Assistance Publique - Hôpitaux de Paris

Not applicable

120

Paris

2026-02-04

Recruiting

IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients

NCT07345169Critical Illness, Intensive Care Patients, Critical Illness Requiring Intensive Care - Sepsis, Critical Illness Requiring Intensive Care - Acute Brain Injury

Assistance Publique - Hôpitaux de Paris

Observational

540

Paris

2026-02-02

Recruiting

Home Treatment of Patients With Active Cancer and Acute Pulmonary Embolism Without HESTIA Criteria.

NCT07315347Active Cancer and Symptomatic or Incidental Pulmonary Embolism Without HESTIA Criteria

Assistance Publique - Hôpitaux de Paris

Not applicable

824

Colombes, Dijon, Paris, Pierre-Bénite, Villejuif, Amiens, Angers, Brest

2026-02-02

Recruiting

Assessment of Airway Opening Pressure in Invasively Ventilated Children

NCT07262541Acute Respiratory Distress Syndrome in Children

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-02-02

Not yet open

Quality of Life Assessment of Caregivers of Patients With Multiple Myeloma

NCT07276230Caregivers of Patients With Multiple Myeloma

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-02-01

Not yet open

" Development of Primary Cultures of Diaphragmatic Myoblasts for Basic Research Purposes "

NCT07380308Endometriosis

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-02-01

Recruiting

Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 Trial

NCT07370987Pancreatic Fistula, Pancreaticoduodenectomy

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-02

Not yet open

Evaluation of Sexual Function After Artificial Urinary Sphincter Implantation

NCT07399509Female Artificial Urinary Sphincter Implantation

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2026-02

Not yet open

Comparison of a Strategy Based on Clinico-biological Monitoring Versus Pre-emptive Rituximab Treatment in Cases of ANCA Reappearance in Granulomatosis With Polyangiitis and Microscopic Polyangiitis.

NCT07451847ANCA Associated Vasculitis (AAV), Polyangiitis (GPA), Microscopic Polyangiitis (MPA)

DrugRituximab

Assistance Publique - Hôpitaux de Paris

Phase 4

Paris

2026-02

Not yet open

Guided Distraction Movement

NCT07248852Venipuncture Pain

Assistance Publique - Hôpitaux de Paris

Not applicable

160

Paris

2026-02

Not yet open

A Phase 2, Single Arm Multicenter, Study Testing Mezigdomide, Carfilzomib, and Dexamethasone (480Kd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

NCT07348393Relapsed or Refractory Multiple Myeloma (RRMM)

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-02

Not yet open

Advanced Classification of Colon Tumors From CT Scans Using Deep Learning for Optimized Treatment Decision-making.

NCT07406958Colonic Neoplasm

Assistance Publique - Hôpitaux de Paris

Observational

1,000

Paris

2026-02

Recruiting

Development of a Cognitive Tool for Rapid and Reliable Screening of Minimal Hepatic Encephalopathy: Pilot Study

NCT06619106Hepatic Pathology (Fibrosis, Cirrhosis, Porto Systemic Shunts)

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2026-01-29

Recruiting

Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia

NCT07120880Major Depressive Disorder (MDD) With Insomnia

Assistance Publique - Hôpitaux de Paris

Phase 3

184

Paris

2026-01-28

Recruiting

Safety of Atezolizumab-Bevacizumab in Liver Transplanted Patients With Advanced Hepatocellular Carcinoma

NCT06254248Liver Transplant, Hepatocellular Carcinoma Recurrent, Systemic Treatment

Assistance Publique - Hôpitaux de Paris

Phase 2

Clichy, Créteil, Lille, Lyon, Montpellier, Paris, Rennes, Strasbourg

2026-01-22

Recruiting

Assessment of Body Composition in Children Treated With Growth Hormone for the Indication of Isolated Non-acquired Growth Hormone Deficiency.

NCT07333521Isolated Non-acquired Growth Hormone Deficiency

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2026-01-13

Recruiting

Development of Diffusion MRI and Tractography Technique for the Detection of Nerve Lesions in Brachial Plexus Injuries

NCT07767708Obstetric Brachial Plexus Palsy

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-01-09

Recruiting

Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease

NCT07300553IBD, Crohn Disease, Ulcerative Colitis (UC)

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-01-02

Not yet open

Renal and Vascular Phenotypic Characterization of Patients With Enamel Renal Syndrome Due to a Pathogenic Variant of the FAM20A Gene and Pathophysiological Study of Ectopic Calcifications

NCT07285421Enamel Renal Syndrome

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-01-01

Not yet open

Dynamic 82-Rb Positron Emission Tomography (PET) for the Grading of KIDney Carcinoma

NCT07346404Renal Cell Carcinoma

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2026-01-01

Not yet open

Cervical Facet Injection of Corticosteroids for the Management of Cervicobrachialgia

NCT07084285Cervicobrachial Neuralgia

DrugDexamethasone

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2026-01

Not yet open

Awake Prone Positioning for Severe Acute Chest Syndrome

NCT06698120Acute Chest Syndrome, Sickle Cell Anemia

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-01

Not yet open

Antibiotics Distribution Study in Peripheral Compartments: Contribution of Microdialysis

NCT07327502Children in Cardiac Intensive Care Requiring Surgery for Congenital Heart Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2026-01

Not yet open

Validation of the French Version of the SERQoL Questionnaire

NCT07372105Smile, Smile Esthetics

Assistance Publique - Hôpitaux de Paris

Observational

120

Paris

2026-01

Recruiting

Cardiovascular Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.

NCT07157670Cardiotoxicity, DPP3, HSCT, Allogeneic Hematopoietic Stem Cell Transplantation

Assistance Publique - Hôpitaux de Paris

Observational

400

Paris

2025-12-25

Recruiting

Obinutuzumab for Remission Induction in Patients With Relapsing PR3-ANCA Granulomatosis With Polyangiitis

NCT06940661Granulomatosis With Polyangiitis

DrugObinutuzumab

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2025-12-19

Recruiting

Study of Neuroinflammation in Multiple Sclerosis by PET-MRI Imaging Using the Radiotracer ([18F]-DPA-714) : a Multicentre Cohort Study (INFLANET)

NCT06280742Multiple Sclerosis

Assistance Publique - Hôpitaux de Paris

Not applicable

Lyon, Paris, Rennes, Toulouse

2025-12-16

Recruiting

Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents

NCT05126914Epilepsy, West Syndrome, Dravet Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

1,000

Angers, Bordeaux, Brest, Lille, Lyon, Marseille, Paris, Strasbourg

2025-12-11

Recruiting

Prognosis of Early-onset Anorexia Nervosa

NCT07311356Anorexia Nervosa

Assistance Publique - Hôpitaux de Paris

Observational

140

Paris

2025-12-05

Recruiting

Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis.

NCT06902805Base-of-thumb Osteoarthritis, Osteoarthritis

DrugOnabotulinumtoxinA

Assistance Publique - Hôpitaux de Paris

Phase 2/3

120

Paris

2025-12-03

Recruiting

Dapagliflozin for Cardio-renal Protection After ICU Discharge

NCT07025629Heart Failure and Chronic Kidney Disease Post-ICU

DrugsFarxiga·Dapagliflozin

Assistance Publique - Hôpitaux de Paris

Phase 3

600

Paris

2025-12-02

Not yet open

Construction of a Reference Corridor to Assess the Value of Combining Innovative Morphological and Functional Analysis Techniques in Pediatric Patient Care Based on Different Pathological Models

NCT07251634Healthy Volunteers

Assistance Publique - Hôpitaux de Paris

Not applicable

125

Paris

2025-12-01

Recruiting

The Effect of Oral SPM Supplementation on INflammation-induced Vascular Ageing in Obese Hypertensive Patients

NCT07038252Hypertension, Obesity

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-11-26

Recruiting

Towards Digital Management of Paediatric Asthma

NCT06902766Pediatric Asthma

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-11-25

Recruiting

Interest of Walking Sticks to Increase Walking Activity of People With Sagittal Imbalance of Spine

NCT07127250Static Spinal Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-11-25

Recruiting

European Project for ctDNA Detection as a Biomarker for Non-invasive Therapy Monitoring in Paediatric Classical Hodgkin Lymphoma

NCT07356882Classical Hodgkin Lymphoma

Assistance Publique - Hôpitaux de Paris

Observational

400

Paris

2025-11-24

Recruiting

EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases

NCT07077304Myocarditis, ANCA Associated Vasculitis, Pericarditis, Systemic Sclerosis

Assistance Publique - Hôpitaux de Paris

Observational

5,000

Paris

2025-11-19

Recruiting

Impact of Vaccine Funding by the National Health Insurance on Vaccination Coverage Among Patients Targeted by Current Vaccination Recommendations and Followed in Outpatient Consultations

NCT07243236Healthcare Providers, Postpartum

Assistance Publique - Hôpitaux de Paris

Observational

2,920

Paris, Fontainebleau, Montereau-Fault-Yonne, Nemours, Rambouillet, Saint-Denis

2025-11-19

Recruiting

Comparison of the Risk of Surgical Site Infections Between Dressings Stopped at Postoperative Day 1 vs Dressings Stopped at Postoperative Day 6+/-1 After Elective Abdominal Surgery

NCT06569862Elective Abdominal Surgery

Assistance Publique - Hôpitaux de Paris

Not applicable

1,288

Paris

2025-11-06

Recruiting

Definition of Sub-phenotypes of Pneumonia Based on the Respiratory Microbiome Composition to Predict Microbial and Clinical Treatment Failures

NCT06916481Community Acquired or Acquiring Hospital Acquired Pneumonia

Assistance Publique - Hôpitaux de Paris

Observational

300

Clichy, Nantes, Paris

2025-11-06

Recruiting

Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis

NCT07010250ANCA Associated Vasculitis, Extramembranous Glomerulopathy, Nephrotic Syndrome, Minimal Change, Interstitial Nephritis

Assistance Publique - Hôpitaux de Paris

Observational

146

Paris

2025-11-03

Recruiting

Study of the Effects of Time-Restricted Feeding on the Immune Function of Individuals With Obesity

NCT06899997Obesity and Obesity-related Medical Conditions

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-11-03

Not yet open

Identifying Biomarkers & Dysregulated Biological Pathways in Blood and Urine of Congenital Central Hypoventilation Syndrome (CCHS) Patients

NCT06997146Congenital Central Hypoventilation Syndrome (CCHS)

DrugBlood and urine sampling

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-11-01

Not yet open

Evaluation of the Effectiveness of an Interdisciplinary Intervention After Acute Coronary Syndrome on Low-Density Lipoprotein Cholesterol Levels

NCT07178444Acute Coronary Syndromes (ACS), Acute Coronary Syndromes

Assistance Publique - Hôpitaux de Paris

Not applicable

230

Corbeil-Essonnes, Lyon, Montpellier, Paris

2025-11

Not yet open

Efficacy of Prostatic Arteries Embolization Using SQUIDPERI

NCT07255508Benign Prostate Hypertrophy(BPH)

Assistance Publique - Hôpitaux de Paris

Observational

100

Marseille, Montpellier, Paris, Strasbourg

2025-11

Recruiting

Corticosteroids Before Extubation in Pediatric Intensive Care Unit

NCT06722118Intensive Care Pediatric

DrugDexamethasone

Assistance Publique - Hôpitaux de Paris

Phase 3

348

Bordeaux, Bron, Garches, Le Kremlin-Bicêtre, Lille, Marseille, Nancy, Paris

2025-10-28

Recruiting

6-year Outcomes in Children After Nifedipine vs Placebo for Preterm Prelabor Rupture of Membranes at 22-33 Weeks

NCT07146451Children Born to Mothers Enrolled in the TOCOPROM Trial

Assistance Publique - Hôpitaux de Paris

Observational

480

Paris

2025-10-28

Recruiting

Treatment of Anaemia After Caesarean With Intravenous Versus Oral Iron and Postpartum Depression

NCT06833788Postpartum Depression (PPD)

DrugFerric Carboxymaltose

Assistance Publique - Hôpitaux de Paris

Phase 4

2,860

Paris

2025-10-22

Recruiting

A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 Gene

NCT07185347Spinocerebellar Ataxia 27B (SCA27B)

DrugFampridine

Assistance Publique - Hôpitaux de Paris

Phase 3

Angers, Bordeaux, Dijon, Lyon, Montpellier, Paris, Rouen, Strasbourg

2025-10-21

Recruiting

Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases

NCT06599411Atopic Dermatitis, Psoriasis, Hidradenitis Suppurativa, Lichen Planus

Assistance Publique - Hôpitaux de Paris

Observational

830

Paris

2025-10-20

Recruiting

Extended Prone Positioning for Intubated ARDS

NCT07126964Acute Respiratory Distress Syndrome

Assistance Publique - Hôpitaux de Paris

Not applicable

800

Paris

2025-10-18

Recruiting

Efficacy of Dexmedetomidine Versus Midazolam Sedation on Extubation Time in Mechanically Ventilated Preterm Infants

NCT06878703PreTerm Neonate, Sedation for Invasive Mechanical Ventilation, Very Preterm Neonates With Sedation for Invasive Mechanical Ventilation

DrugsMidazolam·Dexmedetomidine

Assistance Publique - Hôpitaux de Paris

Phase 3

380

Paris

2025-10-16

Not yet open

Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome)

NCT07081464Ondine Syndrome (Congenital Central Hypoventilation Syndrome)

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-10-15

Not yet open

In Situ Injection of Anti-angiogenics in Patients With Brain Arteriovenous Malformations Not Eligible for Exclusion Treatment

NCT07075757Brain Arteriovenous Malformations

Assistance Publique - Hôpitaux de Paris

Phase 1

Limoges, Nancy, Paris, Rouen

2025-10-01

Not yet open

Bevacizumab in Post-acute Sequelae of COVID-19 : Efficacy and Safety (Pilot Study)

NCT07089719Dyspnea Caused by 2019-nCoV

DrugBevacizumab

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2025-10-01

Recruiting

Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity

NCT07158177Cataract and IOL Surgery

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-10-01

Not yet open

Quantification of Mitral Regurgitation Using 4D MRI Flow : Comparison With 2D MRI Flow and Echocardiography Using the Evolution of Left Ventricular Remodeling as a Reference

NCT07066904Mitral Regurgitation (MR)

Assistance Publique - Hôpitaux de Paris

Not applicable

160

Le Plessis-Robinson, Paris

2025-10-01

Not yet open

CMV-associated Immunomodulation in Renal Transplant Patients

NCT06976008Kidney Transplantation

Assistance Publique - Hôpitaux de Paris

Not applicable

Le Kremlin-Bicêtre, Paris

2025-10-01

Recruiting

Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI)

NCT06887777Pyruvate Dehydrogenase Complex Deficiency Disease

DrugRavicti

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2025-10-01

Not yet open

Biomarkers in Systemic Histiocytosis

NCT07157683Systemic Histiocytosis (Disorder)

Assistance Publique - Hôpitaux de Paris

Observational

500

Paris

2025-10-01

Not yet open

Prospective Evaluation of Probabilistic Predictions of Epileptic Seizure Risk Using the EPIDAY Tool

NCT07068919Epilepsy

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-10

Not yet open

Study of Management and Prognosis of Patients With Acute Myeloblastic Leukemia in Saint-Antoine Hospital

NCT05558943Acute Myeloid Leukemia

Assistance Publique - Hôpitaux de Paris

Observational

750

Paris

2025-10

Not yet open

Characterization of the Fungal Immunopeptidome Involved in the Immunopathological Mechanisms of Psoriasis

NCT06610942Psoriasis

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2025-10

Recruiting

Investigation of Mnesic Capacities in Patients With a Disorder of Consciousness

NCT06959212Disorders of Consciousness

Assistance Publique - Hôpitaux de Paris

Not applicable

175

Paris

2025-09-30

Recruiting

Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care.

NCT07107685Osteoarticular Infections, Intensive Care Patients, Prosthetic Joint Infection

Assistance Publique - Hôpitaux de Paris

Observational

150

Paris

2025-09-24

Recruiting

Genetic Determinants of Myocarditis Induced by Immune-checkpoint Inhibitors

NCT06734689ICI-myocarditis

Assistance Publique - Hôpitaux de Paris

Observational

500

Paris

2025-09-23

Not yet open

Liver Diseases: Extracellular Vesicles as Biomarkers

NCT07185360Liver Diseases

Assistance Publique - Hôpitaux de Paris

Not applicable

845

Paris

2025-09-22

Recruiting

Longitudinal Study of Phenotypic and Developmental Severity in Patients With Dravet Syndrome With SCN1A Gene Mutation

NCT07251673Dravet Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-09-15

Recruiting

Identification of Factors Predictive of the Efficacy of Endoscopic Endoscopic Sleeve Gastroplasty

NCT06153056Obesity

Assistance Publique - Hôpitaux de Paris

Observational

205

Paris

2025-09-09

Recruiting

Evaluation of the Role of Connected Scales in the Therapeutic Care of Hematology Patients

NCT06133426Lymphoma, Non-Hodgkin, Myeloma Multiple

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-09-04

Recruiting

Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy

NCT06351475Peritoneal Neoplasms, Hyperthermic Intraperitoneal Chemotherapy, Intraoperative Care, Fluid Therapy

Assistance Publique - Hôpitaux de Paris

Not applicable

140

Lyon, Montpellier, Paris, Reims, Strasbourg, Villejuif

2025-09-03

Recruiting

Noise Associated With a Mechanical Heart Valve Prosthesis: Does the Memory of Preoperative Information Have an Influence on Postoperative Quality of Life?

NCT07304115Mechanical Heart Valve Prosthesis

Assistance Publique - Hôpitaux de Paris

Observational

180

Paris

2025-09-03

Not yet open

Multicenter Study of Patients With SHANK3 Mutations: Identification of Genes Modificators in Phelan-McDermid Syndrome (EUQ13)

NCT07119606Genetic Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

650

Paris

2025-09-01

Not yet open

Open Label Phase IIa Trial Evaluating the Effect and Safety of Transplantation of Fecal Microbiota in Children With Autism Spectrum Disorders and Gastrointestinal Symptoms

NCT07105267Autism Spectrum Disorder, Fecal Microbiota Transplantation (FMT)

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2025-09-01

Not yet open

Population Pharmacokinetics of Temocillin in Acute Enterobacterial Pyelonephritis in Children

NCT07070102Pyelonephritis

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-09-01

Not yet open

Evaluation of a Multimodal Day Hospital for the Overall Management of Patients With Chronic Inflammatory Bowel Diseases (IBD)

NCT07167186Inflammatory Bowel Disease (IBD), Crohn Disease, Ulcerative Colitis (Disorder)

Assistance Publique - Hôpitaux de Paris

Observational

240

Paris

2025-09

Not yet open

Impact of Comprehensive Geriatric Management on Morbidity and Quality of Life in Elderly Patients Undergoing Major Hepatectomy and Pancreaticoduodenectomy for Cancer

NCT06999512Hepatobiliary Cancer, Pancreatic Cancer

Assistance Publique - Hôpitaux de Paris

Phase 2/3

526

Clermont-Ferrand, Le Kremlin-Bicêtre, Lille, Lyon, Marseille, Paris, Rouen, Toulouse

2025-09

Not yet open

Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk

NCT07142772Megalocephaly

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2025-09

Not yet open

Evaluation of the Superficial Cervical Plexus Block in Oncological Throat and Neck Surgery

NCT07110857ENT Cancers

Assistance Publique - Hôpitaux de Paris

Not applicable

346

Lille, Marseille, Paris, Rouen, Suresnes, Villejuif

2025-09

Not yet open

DIrect Oral Anticoagulation and Bioprothesis Aortic Valve

NCT05687448Aortic Valve Disease

DrugsAspirin 75·Apixaban

Assistance Publique - Hôpitaux de Paris

Phase 3

1,500

Paris

2025-09

Not yet open

Video Analysis and Artificial Intelligence for the Analysis of Upper Limb Movement in Children

NCT07147478Clinical Examination of the Shoulder, Video-assisted Clinical Examination

Assistance Publique - Hôpitaux de Paris

Observational

150

Paris

2025-09

Recruiting

Modeling Amyotrophic Lateral Sclerosis With Fibroblasts

NCT06450691Amyotrophic Lateral Sclerosis

Assistance Publique - Hôpitaux de Paris

Not applicable

110

Paris

2025-08-28

Recruiting

Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease

NCT06818266Sickle Cell Disease, Acute Chest Syndrome

Assistance Publique - Hôpitaux de Paris

Phase 3

130

Paris

2025-08-27

Recruiting

Impact of Iron Overload on the Incidence of Liver Complications in Long-Term Survivors (≥10 Years) of Allogeneic Hematopoietic Stem-Cell Transplantation.

NCT07028112Iron Overload, Hemosiderosis, Liver Diseases, Hematopoietic Stem Cell Transplantation (HSCT)

Assistance Publique - Hôpitaux de Paris

Observational

500

Paris

2025-08-20

Recruiting

Study of the Cellular Response Induced After Vaccination Against the Hepatitis B Virus

NCT06876467Hepatitis B Vaccination, Immune Response, T Cells

Assistance Publique - Hôpitaux de Paris

Observational

115

Paris

2025-08-11

Recruiting

Immunomonitoring of Mold Invasive Infections

NCT06285188Invasive Fungal Disease, Mold Invasive Fungal Infection: Aspergillus, Mucorales, Fusarium, Scedosporium

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-07-28

Recruiting

High-definition Surface Electromyography Markers for the Diagnosis and Monitoring of Sarcopenia

NCT06963359Sarcopenia

Assistance Publique - Hôpitaux de Paris

Not applicable

846

Issy-les-Moulineaux, Ivry-sur-Seine, Paris

2025-07-09

Recruiting

Optimizing the Diagnosis of Pneumocystis in Immunocompromised Patients

NCT06890078Pneumocystis, Immunocompromised Patients

Assistance Publique - Hôpitaux de Paris

Observational

240

Paris

2025-07-08

Recruiting

Assessment of Ovarian Reserve in Patients With Fragile X Premutation

NCT07039734FMR1 Gene Premutation

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2025-07-04

Not yet open

Evaluation of the Impact of a Patient Education Protocol on the Quality of 18F-FDG PET Imaging Indicated for Investigation of Cardiac Inflammation

NCT07029295Infective Endocarditis, Cardiac Sarcoidosis

Assistance Publique - Hôpitaux de Paris

Not applicable

138

Paris

2025-07-01

Recruiting

Phenotypic and Etiological Characterization of Susac Syndrome

NCT06881368Susac Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

180

Paris

2025-07-01

Recruiting

Performance Indicators and Impact on the Care Pathway of Sequencing on the SeqOIA and AURAGEN (Seqogen) Platforms for Oncology Patients

NCT07147465Cancer, NGS, Tumor, RARE DISEASE

Assistance Publique - Hôpitaux de Paris

Observational

3,149

Lyon, Paris

2025-07-01

Recruiting

Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up

NCT06615843Genital Diseases, Female, Ectopic Pregnancy, Uncertain Viability of Pregnancy, Abortion, Missed

Assistance Publique - Hôpitaux de Paris

Not applicable

200

Paris

2025-06-30

Recruiting

Efficacy of Methylprednisolone Pulses in Neuroendocrine Celles Hyperplasia of Infancy : An Early Phase Study

NCT06471556Neuroendocrine Cell Hyperplasia of Infancy

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2025-06-30

Recruiting

Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI

NCT06501482Colorectal Cancer, Colorectal Liver Metastases

Assistance Publique - Hôpitaux de Paris

Phase 3

254

Paris

2025-06-27

Active, closed

Connected Scales to Optimize the Maintenance of Weight Lost After Bariatric Surgery and Limit Failures and Reoperations

NCT06133413Obesity, Severe, Surgery

Assistance Publique - Hôpitaux de Paris

Not applicable

182

Paris

2025-06-26

Recruiting

New Biomarker-based Strategy to Screen and Monitor for Activated Phosphoinositide 3-kinase δ Syndrome

NCT06694363Activated PI3K Delta Syndrome

DrugsUrine samples·Stool samples·Blood samples

Assistance Publique - Hôpitaux de Paris

Observational

Bordeaux, Lille, Marseille, Paris, Toulouse

2025-06-26

Recruiting

Evaluation of the Reproducibility of the Automated Measurement of the Extent of ILD on Chest CT

NCT06743022Interstitial Lung Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

150

Paris

2025-06-24

Recruiting

RESistance of IgA Nephropathy to Conventional and Newly-approved Therapies: an Observational, Real-life Study (RESIGAN)

NCT06926244IgA Nephropathy (IgAN)

Assistance Publique - Hôpitaux de Paris

Observational

800

Paris

2025-06-23

Recruiting

Stroke Prevention In Ischemic Stroke With Covert Atrial Fibrillation

NCT06486792Stroke, Ischemic Stroke, Cerebral Infarction, Atrial Fibrillation

DrugsDabigatran·Apixaban·Rivaroxaban·Aspirin

Assistance Publique - Hôpitaux de Paris

Phase 4

1,148

Paris

2025-06-18

Recruiting

Prevention Strategy for Respiratory Syncytial Virus (RSV) Infections in Infants in France

NCT06881953RSV Infection

Assistance Publique - Hôpitaux de Paris

Observational

400

Paris

2025-06-17

Recruiting

Small Bowel Capsule Endoscopy in Lynch Syndrome

NCT07472686MMR Mutation, Small Bowel Adenoma, Small-bowel Adenocarcinoma, Lynch Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

400

Paris

2025-06-16

Recruiting

Long Term Follow-up of Cardiac Arrest Survivors Exposed to Ultra-rapid Cooling

NCT07028372Cardiac Arrest (CA), Resuscitated Sudden Cardiac Death, Post Cardiac Arrest Patient Who Was Treated by Hypothermia Protocol

Assistance Publique - Hôpitaux de Paris

Observational

Angers, Paris

2025-06-11

Not yet open

Role of Viral Reservoir, Immune Activation and Depletion in Persistent Viremia Persistent Viremia in People Living With HIV on Antiretroviral Therapy

NCT07015164HIV

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-06-10

Recruiting

Evaluation of the Anti-VZV Vaccine Response of Patients With Immune-mediated Systemic Inflammatory Diseases Vaccinated in the Care Setting

NCT07047053Vaccination Varicella-zoster Virus, Immune-mediated Systemic Inflammatory Diseases

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-06-10

Recruiting

Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis

NCT04871191Granulomatosis With Polyangiitis, Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

DrugsTofacitinib·Tocilizumab·Rituximab

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2025-06-06

Recruiting

A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department

NCT06733974Grief Disorder, Prolonged

Assistance Publique - Hôpitaux de Paris

Not applicable

924

Paris

2025-06-04

Recruiting

Involvement of General Practitioners in Lung Cancer Screening

NCT06956040Lung Cancer

Assistance Publique - Hôpitaux de Paris

Not applicable

500

Paris

2025-06-02

Not yet open

Prevention of Lung Injury Induced by Mechanical Ventilation in Acute Respiratory Distress Syndrome ARDS Patients

NCT06835881Adult Respiratory Distress Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-06

Recruiting

Evaluation of the Efficacy of Dd-cfDNA in Routine Patient Care in Kidney Transplant Recipients"

NCT06406179Renal Transplantation

Assistance Publique - Hôpitaux de Paris

Not applicable

500

Paris, Toulouse

2025-05-31

Recruiting

Antagonization of Heparin With Protamine Sulfate After TAVI

NCT06215378Aortic Valve Stenosis, Heart Valve Diseases

Assistance Publique - Hôpitaux de Paris

Phase 3

940

Paris

2025-05-25

Recruiting

Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3

NCT06457386Staphylococcus Aureus, Bacteremia, Infective Endocarditis

Assistance Publique - Hôpitaux de Paris

Not applicable

700

Paris

2025-05-14

Recruiting

Evaluation of Long-term Immunogenicity of a Boost Dose of MVA-BN Vaccine

NCT06885853Monkeypox

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-05-07

Recruiting

A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia

NCT06860269Acute Lymphoblastic Leukemia

DrugsPonatinib·Isatuximab·Blinatumomab

Assistance Publique - Hôpitaux de Paris

Phase 2/3

1,200

Paris

2025-05-06

Recruiting

Characterization of Autoreactive Regulatory and Conventional CD4 T Cells in Recent Onset Type 1 Diabetes and Control Individuals

NCT06427421Type 1 Diabetes

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-05-06

Recruiting

Optimization of Routine Obstetric and Neonatal Care in the Management of Severe Perinatal Asphyxia in Term or Near-term Newborns: Analysis of Sub-optimal Care

NCT06322732Perinatal Asphyxia

Assistance Publique - Hôpitaux de Paris

Observational

336

Paris

2025-05-05

Recruiting

Kinetics of INF-γ Production in Intensive Care Patients

NCT06549374Intensive Care

Assistance Publique - Hôpitaux de Paris

Observational

200

Annecy, Clermont-Ferrand, Lyon, Paris

2025-04-24

Recruiting

Links Between Cognitive Deficits During Normal or Pathological Aging and Slow Waves Measured in EEG

NCT06501495Aging, Alzheimer Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-04-24

Recruiting

Determining Elements of Anti-Fungal Immunity in BURN Patients

NCT06828458Burn

Assistance Publique - Hôpitaux de Paris

Observational

327

Paris

2025-04-23

Recruiting

Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis

NCT05989152Prosthetic Valve Endocarditis

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-04-17

Recruiting

Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial)

NCT06344442Acute Kidney Injury Post Liver Transplantation

DrugsArginine Vasopressin·Norepinephrine

Assistance Publique - Hôpitaux de Paris

Phase 3

304

Paris

2025-04-16

Recruiting

Non-invasive Diagnosis of Idiopathic Nephrotic Syndromes

NCT06820866Idiopathic Nephrotic Syndrome (INS)

Assistance Publique - Hôpitaux de Paris

Observational

265

Paris

2025-04-15

Recruiting

Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location

NCT06834646Cancer, Cancer Remission

Assistance Publique - Hôpitaux de Paris

Observational

2,000

Paris

2025-04-12

Recruiting

Effects of Nasal Airflow on Sleep in Tracheotomized Patients

NCT06547463Patients With Prolonged Weaning

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-04-10

Recruiting

Evaluation of Software for Interpreting Virological Results Indicated for the Diagnosis of Cytomegalovirus (CMV) Infection During Pregnancy and Intended for Health Professionals

NCT06694428Cytomegalovirus Infections, Maternal Primary Cytomegalovirus Infection

Assistance Publique - Hôpitaux de Paris

Observational

491

Limoges, Paris, Villejuif

2025-04-04

Recruiting

Deficit Hyperactivity Disorder / Substance Use Disorder Comorbidity in Integrated Treatment

NCT06858527Attention Deficit Hyperactivity Disorder (ADHD), Substance-related Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

132

Paris

2025-04-01

Not yet open

Diffusion Endometriosis MRI to Detect and Quantify Symptomatic Neurological Impairment in Pelvic Endometriosis

NCT06908655Endometriosis

Assistance Publique - Hôpitaux de Paris

Not applicable

110

Paris

2025-04-01

Recruiting

Liquid Biopsies for the Detection of Somatic Mutations in bAVMs

NCT06494358Brain Arterial Disease

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-04-01

Not yet open

Financial Incentives and Weight Loss in Failed Bariatric Surgery

NCT06910735Obesity, Obesity Recidivism

Assistance Publique - Hôpitaux de Paris

Not applicable

264

Bobigny, Colombes, Créteil, Marseille, Nantes, Orléans, Paris, Poitiers

2025-04

Recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy

NCT06443606BPC, Non Optimal Response to UDCA

Assistance Publique - Hôpitaux de Paris

Phase 3

108

Paris

2025-03-27

Not yet open

Impact of Vestibular Function on Deaf Infants' Activities of Daily Living

NCT06909266Vestibular Dysfunction, Hearing Loss, Motor Development

Assistance Publique - Hôpitaux de Paris

Observational

105

Paris

2025-03-27

Recruiting

Research for Plasma Biomarkers Associated With Fatigue in Thrombocytopenic Patients

NCT06979765Thrombopenia

DrugBlood sampling

Assistance Publique - Hôpitaux de Paris

Not applicable

280

Paris

2025-03-26

Recruiting

Craniopharyngioma and Pregnancies

NCT06801756Craniopharyngioma

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2025-03-24

Recruiting

Prevalence, Determinants and Consequences of Dyspnea During Weaning in Critically Ill Obese Patients

NCT06867354Obesity, Obesity With Complications, Weaning From Mechanical Ventilation in Care Unit, Dyspnea

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-03-21

Recruiting

Evaluation of Patient Care Support for Cirrhosis and/or Liver Transplants

NCT06544863Cirrhosis

Assistance Publique - Hôpitaux de Paris

Observational

3,000

Paris

2025-03-19

Recruiting

Cartography of Social Cognition Network and Their Alterations in Patients With Epilepsy

NCT05527093Epilepsy, Drug Resistant Epilepsy

Assistance Publique - Hôpitaux de Paris

Not applicable

Gif-sur-Yvette, Paris

2025-03-19

Recruiting

Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease

NCT06582121Parkinson Disease, REM Sleep Behavior Disorder (iRBD)

Assistance Publique - Hôpitaux de Paris

Not applicable

457

Clermont-Ferrand, Lille, Lyon, Nantes, Nîmes, Paris

2025-03-18

Recruiting

Evaluation of the HPA Axis in Patients With Vasoplegic Syndrome After Cardiac Surgery

NCT06371976Vasoplegic Syndrome in Adult Cardiac Surgery

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2025-03-05

Recruiting

Refractory Cardiac Arrest Treated On Field By ECMO

NCT06397417Out-of-Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation

Assistance Publique - Hôpitaux de Paris

Observational

840

Paris

2025-03-05

Recruiting

Geriatric Transitional Care for Older Patients Discharged From the Emergency Department: Impact on Early Readmissions

NCT05814328Hospital Readmissions of Elderly Patients

Assistance Publique - Hôpitaux de Paris

Not applicable

1,322

Paris

2025-03-04

Recruiting

CRACK-TARGET 1: Descriptive Study of Observed Behavioral Sensitization and Expectations

NCT06050304Cocaine Use Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-03-04

Not yet open

Non-Invasive Monitoring of Pediatric Kidney Transplant Recipients and Immunosuppression Personalization: an Open-labeled Multicenter Randomized Controlled Study

NCT06761482Pediatric Kidney Disease, Transplant;Failure,Kidney

Assistance Publique - Hôpitaux de Paris

Not applicable

160

Paris

2025-03-01

Not yet open

Population Pharmacokinetics of Paracetamol in Overweight and Obese Children

NCT06135389Overweight, Obesity

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-03

Not yet open

Silver Russell Syndrome, Parental Fertility and Assisted Reproductive Technology

NCT06878716Syndrome, Russell Silver

Assistance Publique - Hôpitaux de Paris

Observational

125

Paris

2025-03

Not yet open

Evaluation of the Effectiveness of Routine Nurse Education in Prescribing Nicotine Replacement Therapy for Hospitalized Smokers in a University Hospital

NCT06789536Smoking Addiction

Assistance Publique - Hôpitaux de Paris

Not applicable

442

Paris

2025-03

Recruiting

Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis

NCT06354322AA Amyloidosis, Autoinflammatory Disease

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2025-02-26

Recruiting

Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine

NCT06464146Limb Injury

DrugsNaCl·Fentanyl·Ketamine·Morphine

Assistance Publique - Hôpitaux de Paris

Phase 3

300

Boulogne-Billancourt, Lille, Marseille, Nantes, Paris

2025-02-26

Recruiting

Use of Eye Tracking to Study Social Perception Abnormalities in Children With Angelman Syndrome

NCT06737718Angelman Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-02-25

Recruiting

Diagnostic Performance of a Combination of Leukocyte Cell Surface Markers in Predicting the Risk of Severe Bacterial Infection in Febrile Children Under Three Months of Age in the Emergency Department: a Pilot Study.

NCT06618989Children Under 3 Months of Age With Fever

Assistance Publique - Hôpitaux de Paris

Observational

180

Paris

2025-02-24

Recruiting

Evaluation of Neurodevelopmental Trajectories in Children According to the Glycemic Profile Associated With Early Treatment Using an Automated Delivery System in Children With Type 1 Diabetes

NCT06461065Diabetes

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-02-20

Active, closed

Preventing Iatrogenic Dependence Linked to Hospitalisation in Elderly Patients Hospitalised in Acute Geriatrics

NCT06449053an Acute Pathology

Assistance Publique - Hôpitaux de Paris

Not applicable

918

Paris

2025-02-11

Recruiting

Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction

NCT06518694Heart Failure

Assistance Publique - Hôpitaux de Paris

Phase 3

1,300

Paris

2025-02-11

Recruiting

Home-based Cycling for People With Lumbar Spinal Stenosis

NCT04075539Symptomatic Lumbar Spinal Stenosis

Assistance Publique - Hôpitaux de Paris

Phase 3

302

Paris

2025-02-10

Not yet open

Kinematic Analysis of Latissimus Dorsi Transfer Results for Shoulder External Rotation Resuscitation

NCT06845228Osbtetric Brachial Plexus Palsy

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-02

Not yet open

Evaluation of the Incidence of Psychiatric Disorders As a Function of First-line Antiepileptic Drug Prescribing Practices: Use of Assurance Maladie Databases

NCT06829693Epilepsy, Side Effects of Drugs

Assistance Publique - Hôpitaux de Paris

Observational

355,000

Paris

2025-02

Recruiting

ORal Antibiotics in Acute Mesenteric Ischemia

NCT06387147Acute Mesenteric Ischemia

DrugsGentamicin·Metronidazole

Assistance Publique - Hôpitaux de Paris

Phase 3

196

Clichy, Paris

2025-01-31

Recruiting

Effects of Nasal Ventilation on Cerebral and Pulmonary Function in Orally Intubated Patients

NCT06438302Hypoxemic Acute Respiratory Failure

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-01-31

Not yet open

Genetic and Clinical Characterization of Type 1 and 2 Narcolepsy in Adult and Pediatric Black and North African Populations

NCT06786377Narcolepsy

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2025-01-30

Recruiting

Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years

NCT06646497Aplastic Anemia

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris, Amiens, Angers, Besançon, Bordeaux, Caen, Clamart, Clermont-Ferrand

2025-01-24

Recruiting

Experiences Reported by Siblings of Children Hospitalized in the PICU

NCT06664333Intensive Care Pediatric

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2025-01-21

Recruiting

Choroid Plexus Dysfunction in Neurological Diseases

NCT06403189Plexus Choroideus, Metabolic Syndrome

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2025-01-20

Recruiting

Early Immunotherapy with Intravenous Immunoglobulin, Cyclophosphamide and Methylprednisolone in Patients with Anti-Hu-associated Paraneoplastic Sensory Neuronopathy

NCT06373211Paraneoplastic Sensory Neuronopathy

DrugsImmunoglobulins·Methylprednisolone·Cyclophosphamide

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2025-01-10

Recruiting

Preoxygenation for Tracheal Aspirations in Intensive Care

NCT06421012ICU Patients Under Invasive Mechanical Ventilation

Assistance Publique - Hôpitaux de Paris

Not applicable

2,260

Paris

2025-01-07

Recruiting

Determining Paediatric Usual Values for Hormones Dosages by LC-MS/MS

NCT06694415Control Condition

Assistance Publique - Hôpitaux de Paris

Observational

1,500

Paris

2025-01-02

Not yet open

A Clinical Decision Support Tool for Assessing the Ability to Decide on Returning Home in Elderly Patients with Cognitive Impairments

NCT06669559The Patient's Ability to Decide to Return Home After Hospitalization

Assistance Publique - Hôpitaux de Paris

Not applicable

238

Paris

2025-01

Not yet open

Prevalence and Severity of Cramps in Chronic Kidney Disease Patients

NCT06737094Cramps, Chronic Kidney Disease(CKD)

Assistance Publique - Hôpitaux de Paris

Observational

250

Paris

2025-01

Recruiting

Prospective Evaluation of the Results of Multidisciplinary Follow-up After a Transitional Consultation for Esophageal Atresia

NCT06860919Esophageal Atresia

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-12-19

Recruiting

Respiratory and Psychological Impact of Elective Surgery of Congenital Lung Malformations

NCT06424392Congenital Lung Malformations

Assistance Publique - Hôpitaux de Paris

Observational

434

Paris

2024-12-19

Recruiting

Evaluation of a New Bi-Condylar Total Knee Prosthesis (TKP) With All-Ceramic Friction (The Forgotten Knee)

NCT06592248Knee Osteoarthritis

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-12-19

Recruiting

Study Comparing Therapy for Advanced Relapsed/Refractory Multiple Myeloma With and Without Dexamethasone

NCT06561854Multiple Myeloma, Relapse Multiple Myeloma

DrugDexamethasone

Assistance Publique - Hôpitaux de Paris

Phase 3

318

Paris

2024-12-12

Recruiting

Investigation of Sky Automatic Technologies in Pediatrics

NCT06400992Hearing Loss

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-12-11

Recruiting

Association of Dysbiosis and Immune Response in Bronchiolitis in Under 12 Months -Old Infants

NCT06161285Bronchiolitis

Assistance Publique - Hôpitaux de Paris

Observational

120

Clamart, Garches, Paris

2024-12-06

Recruiting

Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center

NCT07205861Thrombotic Thrombocytopenic Purpura (TTP), Immune Thrombotic Thrombocytopenic Purpura, Thrombotic Microangiopathies, Microangiopathy, Thromboic

Assistance Publique - Hôpitaux de Paris

Observational

1,200

Paris

2024-12-02

Recruiting

Host Genome Methylation: a Screening Tool in Anal Cancer Detection

NCT06792604Anal Cancer

Assistance Publique - Hôpitaux de Paris

Not applicable

770

Paris

2024-11-22

Recruiting

Intestinal Akkermansia Muciniphila in Prostate Cancer

NCT06242509Metastatic Castration-resistant Prostate Cancer

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-11-20

Recruiting

Reliability of Minimally Trained Operator's Velocity-Time Integral Measurement Guided by Artificial Intelligence VTI

NCT06486467Velocity-time Integral Measurement, Critically Ill Patients, Tissue Hypoperfusion

Assistance Publique - Hôpitaux de Paris

Not applicable

100

Limoges, Paris

2024-11-14

Recruiting

Ruxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis (R-HLH)

NCT05762640Haemophagocytic Lymphohistiocytosis

DrugRuxolitinib

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2024-11-10

Recruiting

New Adjuvant Vaccine in Glioblastoma, a Phase 1/2a Study

NCT06622434Newly Diagnosed Glioblastoma

DrugImmunization

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Paris, Marseille

2024-11-08

Recruiting

Early Assessment of Cardiac Function After Treatment With CAR-T Cells

NCT06350994Car T- Cell, Hematologic Malignancy, Acute Lymphoblastic Leukemia, Lymphoma, B-Cell

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-11-07

Recruiting

Validation Study of the Performance of the French Version of the Autism Mental Status Examination Scale as a Tool for Identifying Autism Spectrum Disorder in Adults

NCT06549179Autism Spectrum Disorder

Assistance Publique - Hôpitaux de Paris

Observational

410

Paris

2024-11-04

Not yet open

Impact of Breast Milk miRNAs on the Infant Gut Microbiota

NCT06651216Breast Milk, Stools

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2024-11-01

Recruiting

Precision Medicine in Alzheimer's Disease : Integration of Resilience Metrics and Risk Factors - Validation Cohort BioCogBank-AD

NCT06582199Alzheimer Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

244

Paris

2024-10-31

Recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

NCT06147414Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, Including, Sickle Cell Disease, Cystic Fibrosis, Fragile X Syndrome

DrugBlood sample

Assistance Publique - Hôpitaux de Paris

Observational

550

Paris

2024-10-23

Recruiting

3D Ultrasound Myocardial Mechanical Wave Measurements

NCT06648577Chronic Primary Mitral Regurgitation

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-10-09

Recruiting

The Effect of Pulse Field Ablation on Atrial Mechanics in Catheter Ablation of Paroxysmal Atrial Fibrillation

NCT06557876Atrial Fibrillation Paroxysmal

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-10-09

Recruiting

Registry of PHAcoemulsification for Cataract Surgery

NCT06659419Cataract

Assistance Publique - Hôpitaux de Paris

Observational

100,000

Paris

2024-10-01

Recruiting

Effect of Genicular Arteries Embolization in Symptomatic Knee Osteoarthritis LipioJoint-2

NCT06497140Knee Osteoarthritis

Assistance Publique - Hôpitaux de Paris

Phase 3

130

Paris

2024-09-30

Recruiting

Dexamethasone and Pregnancy: Maternal Effects

NCT06259994Dexamethasone During Pregnancy

Assistance Publique - Hôpitaux de Paris

Observational

Bordeaux, Bron, Grenoble, Le Kremlin-Bicêtre, Lille, Nantes, Paris, Toulouse

2024-09-30

Recruiting

Time Required to Dissolve Urate Deposits

NCT06669000Gout

Assistance Publique - Hôpitaux de Paris

Observational

250

Paris

2024-09-24

Recruiting

In Utero Surgery for Fetal Myelomeningocele: Decision-making Mechanisms and Psychological Impact of Prenatal Therapy

NCT06796972Myelomeningocele

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-09-23

Recruiting

A Multicenter Pharmacoepidemiological Cohort on Real Life Use of Semaglutide in Adolescents or Adults With Monogenic Obesity

NCT06380426Monogenic Obesity

Assistance Publique - Hôpitaux de Paris

Observational

175

Paris

2024-09-19

Recruiting

Contribution of 3D Modeling in Surgical Management of Pediatric Retroperitoneal and Pelvic Tumors

NCT06418243Pelvic Tumor, Retroperitoneal Tumor

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-09-16

Recruiting

Analysis of Parental Support in Families Using the LENA After Early Cochlear Implantation

NCT05917496Profound Congenital Deafness, Cochlear Implantation

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-09-13

Recruiting

Diagnostic Evaluation of Dementia with Lewy Bodies Using a Multimodal Approach

NCT06068361Lewy Bodies Disease, Alzheimer Disease, Cognitive Impairment

Assistance Publique - Hôpitaux de Paris

Observational

130

Paris

2024-09-11

Recruiting

Detection of Plasma DNA of Renal Origin in Kidney Transplant Patients

NCT06026592Acute Kidney Injury, Renal Transplantation

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-09-02

Recruiting

Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA)

NCT06083090Axial Spondyloarthritis (axSPA)

Assistance Publique - Hôpitaux de Paris

Not applicable

Bobigny, Créteil, Paris

2024-08-27

Active, closed

Contribution of the Evaluation of Body Composition by Connected Scale in the Effectiveness of a Reconditioning Program Through Physical Activity Adapted for Patients Suffering From Chronic Diseases

NCT06119594Chronic Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-08-27

Recruiting

Rapid Molecular Diagnosis and Detection of Emerging Infectious Diseases in Patients With Tropical Fever (Tropifever)

NCT06539325Infectious Diseases in Febrile Patients Returning From Tropical Countries

Assistance Publique - Hôpitaux de Paris

Not applicable

564

Paris

2024-08-26

Recruiting

Detection of Circulating Kidney DNA in Kidney Transplant Patients Facing an Episode of Graft Rejection

NCT06351488Kidney Transplant, Rejection

Assistance Publique - Hôpitaux de Paris

Observational

319

Paris

2024-08-21

Recruiting

Study of the Prevalence of Pediatric Eating Disorders in Inherited Metabolic Diseases With Dietary Treatment

NCT06471842Inherited Metabolism Disease

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2024-08-21

Recruiting

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections

NCT06334497Cytomegalovirus Infection

DrugsValganciclovir·Letermovir

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2024-08-14

Recruiting

Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis

NCT06305468Toxoplasmosis

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2024-08-01

Recruiting

Incidence and Impact of ICU-acquired Diaphragm Weakness

NCT06420999Diaphragm Dysfunction

Assistance Publique - Hôpitaux de Paris

Observational

194

Paris

2024-07-29

Recruiting

Integrative Epidemiology of Prognosis in Patients With Acute Alcoholic Hepatitis at AP-HP

NCT07262515Acute Alcoholic Hepatitis

Assistance Publique - Hôpitaux de Paris

Observational

1,400

Paris

2024-07-19

Recruiting

Multi-modal Characterisation of Hepatocellular Carcinoma (HCC) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort

NCT06334965Hepatocellular Carcinoma, Radioembolization

Assistance Publique - Hôpitaux de Paris

Not applicable

180

Clichy, Nantes, Paris

2024-07-18

Recruiting

Colchicine Versus Placebo in Acute Myocarditis Patients

NCT05855746Acute Myocarditis

DrugsColchicine Pill·Colchicine

Assistance Publique - Hôpitaux de Paris

Phase 3

300

Bron, Paris

2024-07-16

Recruiting

Healthy Stool Volunteer Donors for Fecal Microbiota Transplantation Trials

NCT06478823Gastro-Intestinal Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

400

Paris

2024-07-08

Recruiting

Effects of Intravascular Administration of Mesenchymal Stromal Cells Derived from Wharton's Jelly of the Umbilical Cord on Systemic Immunomodulation and Neuroinflammation After Traumatic Brain Injury.

NCT06146062Traumatic Brain Injury

Assistance Publique - Hôpitaux de Paris

Phase 2

Clamart, Clichy, Paris

2024-06-25

Recruiting

Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering From Gender Dysphoria

NCT06351501Gender Dysphoria

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris, Le Kremlin-Bicêtre

2024-06-25

Recruiting

Peripheral Tissue Perfusion in Intensive Care

NCT06384287Acute Circulatory Failure

Assistance Publique - Hôpitaux de Paris

Observational

180

Paris

2024-06-22

Recruiting

Quality of Life Related to the Care of Women Living With HIV During the Perinatal Period

NCT06666530HIV

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2024-06-19

Recruiting

Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic High-Potency Single Antiplatelet Therapy to Neutralize Bleeding Complications in Patients With High Bleeding Risk Beyond One Month After an Acute Coronary Syndrome

NCT05577988MYOCARDIAL INFARCTION

Assistance Publique - Hôpitaux de Paris

Phase 3

2,468

Paris

2024-06-18

Not yet open

Study and Modulation of Immune Responses in Primary and Metastatic Colon Cancers

NCT06435689Colon Cancer, Peritoneal Carcinoma

Assistance Publique - Hôpitaux de Paris

Observational

500

Paris

2024-06-15

Recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy

NCT06336733FMF

DrugAnakinra

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2024-06-04

Not yet open

Evaluation of [68Ga]Ga-PentixaFor PET Imaging for the Identification of Unilateral Adrenal Secretion of ALdosterON in Patients With Primary Aldosteronism

NCT06478875Primary Aldosteronism

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2024-06

Recruiting

Evaluation of Stereotactic Body Radiotherapy as a Bridge Therapy for Hepatocellular Carcinoma Patients Enlisted for Liver Transplantation

NCT06218420Hepatocellular Carcinoma

Assistance Publique - Hôpitaux de Paris

Phase 2

139

Paris

2024-05-31

Recruiting

Impact of Confirmed Autoimmune Encephalitis on Brain Glucose Metabolism

NCT06079294Autoimmune Encephalitis

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-05-31

Recruiting

Relevance of a Telemedicine Monitoring in the Management of Depression

NCT06076317Major Depressive Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

836

Paris

2024-05-27

Recruiting

Drugs Experience for Adolescents With Anorexia

NCT06211517Anorexia Nervosa, Psychotropic Drugs, Adolescent

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-05-20

Recruiting

Epidemiology and Management of Malnutrition of Patients Hospitalized at the Pitié-Salpêtrière Hospital: a One-day Survey Combined With Focus Groups (Mixed Methods)

NCT06317402Malnutrition

Assistance Publique - Hôpitaux de Paris

Observational

385

Paris

2024-05-15

Recruiting

Combination of Leukocyte Cell Surface Biomarkers Measured by Cytometry, to Differentiate Bacterial From Viral Infections in Emergency Department: a Multicentric Cohort for the Validation of Diagnostic Performances

NCT06155266Bacterial and Viral Infections

Assistance Publique - Hôpitaux de Paris

Observational

500

Paris

2024-05-14

Recruiting

Belief Updating in Treatment Resistant Depression

NCT05577247Treatment Resistant Depression

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-05-13

Recruiting

Announcement of Rare Metabolic Diseases in Systematic Newborn Screening: the Phenylketonuria Experience.

NCT06289348Phenylketonuria

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2024-05-07

Recruiting

Prediction Models for Cardiovascular and Neurocognitive Disease Risk in the General Population

NCT05951764Anesthesia, Local, Anesthesia

Assistance Publique - Hôpitaux de Paris

Observational

396

Paris

2024-05

Recruiting

EDN and Eosinophilic Esophagitis

NCT06387030Eosinophilic Esophagitis

DrugsStool sampling·Urine sampling·Blood sampling

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-04-19

Recruiting

Understanding the Mechanisms of Autism : an MRI and Social Cognition Study

NCT06334588Autism Spectrum Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

160

Paris

2024-04-17

Recruiting

Use of a Physiotherapy Assessment to Predict Extubation Failure in Mechanically Ventilated Patients: the EPIC Assessment

NCT06450678Mechanical Ventilator Weaning, Mechanical Ventilation

Assistance Publique - Hôpitaux de Paris

Observational

330

Paris

2024-04-15

Recruiting

Cannabidiol as an add-on Treatment During Inpatient Alcohol Cessation : CBD-OH

NCT05860699Severe Alcohol Use Disorder (DSM 5)

Assistance Publique - Hôpitaux de Paris

Phase 2

210

Créteil, Clamart, Clermont-Ferrand, Colombes, Bobigny, Paris, Sevran, Montpellier

2024-04-08

Recruiting

Evaluation of an Intensive Training Program for Patients with Hereditary Spastic Paraparesis SPG4/Spast

NCT06229626Hereditary Spastic Paraparesis

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-04-04

Recruiting

Alleviating Persistent Dyspnea in Amyotrophic Lateral Sclerosis Patients Treated With Non-Invasive Ventilation Through Immersive Virtual Reality

NCT06021938Amyotrophic Lateral Sclerosis

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-04-04

Recruiting

Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study.

NCT06119516ARDS, Human, Obesity, Morbid

Assistance Publique - Hôpitaux de Paris

Not applicable

Angers, Le Kremlin-Bicêtre, Lyon, Paris, Poitiers

2024-04-04

Recruiting

Study of the Prevalence of Endometriosis and Adenomyosis

NCT06211569Elective Fertility Preservation

Assistance Publique - Hôpitaux de Paris

Observational

400

Paris

2024-04-04

Recruiting

Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population

NCT05949567Urodynamic Exam, Neurologic Disorder

Assistance Publique - Hôpitaux de Paris

Not applicable

160

Paris

2024-04-02

Not yet open

Pembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV Infection

NCT06276504Progressive Multifocal Leukoencephalopathy

DrugPembrolizumab

Assistance Publique - Hôpitaux de Paris

Phase 2/3

Paris

2024-04

Recruiting

Genetic and Molecular Characterization of Nervous System Lesions

NCT06314607Brain Tumor, Brain Lesion (General)

Assistance Publique - Hôpitaux de Paris

Observational

10,000

Paris

2024-03-26

Recruiting

Impact of YOGA on the Quality of Life and Well-being of Heart Failure Patients

NCT06019169Chronic Heart Failure

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-03-26

Recruiting

Impact of Surgical Approach on Adaptation of Posture-respiratory Coupling

NCT06276530Resectable Lung Non-Small Cell Carcinoma

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-03-25

Recruiting

Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness

NCT05740735Disorder of Consciousness

Assistance Publique - Hôpitaux de Paris

Observational

114

Paris

2024-03-25

Recruiting

Biomarkers for Diagnostic, Prognostic and of Response to Treatment in Adult Langerhans Cell Histiocytosis

NCT06197204Histiocytosis, Langerhans-Cell

Assistance Publique - Hôpitaux de Paris

Observational

570

Paris

2024-03-25

Recruiting

Multi-modal Characterisation of Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort

NCT06256705Gastroenteropancreatic Neuroendocrine Tumor, Radiotherapy

Assistance Publique - Hôpitaux de Paris

Not applicable

Clichy, Nantes, Paris

2024-03-25

Recruiting

Bedside Bone Biopsy in Diabetic Foot Osteomyelitis

NCT06066801Subjects With Diabetes and DFU With a Suspicion of DFO

Assistance Publique - Hôpitaux de Paris

Not applicable

320

Paris

2024-03-14

Recruiting

Circadian Rhythm and Other Factors in Memory Clinic Patients

NCT05977712Dementia

Assistance Publique - Hôpitaux de Paris

Observational

1,200

Paris

2024-03-06

Not yet open

Impact of Early Mobilization on SAH Patients Physiological Parameters

NCT06286683Subarachnoid Hemorrhage

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2024-03

Not yet open

Ifenprodil as a ReMyelinating repurpOsed Drug in Multiple Sclerosis

NCT06330077Multiple Sclerosis, Remitting Relapsing Multiple Sclerosis

Assistance Publique - Hôpitaux de Paris

Phase 2

Bron, Paris

2024-03

Recruiting

Veno-arterial ExtraCorporeal Membrane Oxygenation to Reduce Morbidity and Mortality Following Lung TransPlant

NCT05664204The Number of Ventilator-free Days in the 28 Days Following LT

Assistance Publique - Hôpitaux de Paris

Not applicable

200

Paris, Suresnes

2024-02-29

Recruiting

Multimodal Study of the Human Brain Epilepsy Tissue

NCT06022055Focal Drug-resistant Epilepsy

Assistance Publique - Hôpitaux de Paris

Not applicable

300

Paris

2024-02-29

Recruiting

Efficacy of 7 Days Versus 14 Days of Antibiotic Therapy for Acute Pyelonephritis in Kidney Transplant Recipients, a Multicentre Randomized Non-inferiority Trial.

NCT05597540Pyelonephritis Acute, Kidney Transplant Infection

Assistance Publique - Hôpitaux de Paris

Phase 3

470

Bordeaux, Boulogne-Billancourt, Créteil, Lyon, Nantes, Paris, Toulouse

2024-02-22

Recruiting

Impact of Robotic Cochlear Implantation on Hearing Performance in Noise

NCT06248398Severe to Profound Hearing Loss

Assistance Publique - Hôpitaux de Paris

Not applicable

140

Paris

2024-02-20

Recruiting

Assessment of the Impact of Early Treatment for Anorexia Nervosa in a Day Hospital on Food Symptomatology, the Outcome of Young Patients, and the Family Experience

NCT06218472Anorexia Nervosa

Assistance Publique - Hôpitaux de Paris

Observational

164

Paris

2024-02-19

Recruiting

Contribution of the CEST Sequence in the Characterization of Radionecrosis of Brain Metastases of Pulmonary Origin

NCT05977803Brain Metastases, Radionecrosis, Pulmonary Cancer

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-02-15

Recruiting

Clinical and Urodynamic Assessment of Bladder Sensation in Multiple Sclerosis

NCT05772637Overactive Bladder

Assistance Publique - Hôpitaux de Paris

Not applicable

113

Paris

2024-02-14

Recruiting

Studies of Phenotypic and Functional Characteristics of Circulating Neutrophil Subpopulations in Patients With Lung Cancer

NCT06244355Lung Cancer

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2024-02-12

Recruiting

European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study

NCT06235385Heart Valve Diseases, Multiple Valve Disease, Unspecified, Aortic Valve Disease, Aortic Valve Stenosis

Assistance Publique - Hôpitaux de Paris

Observational

1,500

Paris

2024-02-07

Recruiting

Peripheral Serotonin and Albinism

NCT06138509Oculocutaneous Albinism

Assistance Publique - Hôpitaux de Paris

Observational

160

Paris

2024-02-06

Recruiting

Fetal Cell Receptors Repertoire

NCT06031714Venous Ulcer, Sickle Cell Ulcer, Diabetic Ulcer, Post-partum Women

Assistance Publique - Hôpitaux de Paris

Not applicable

160

Paris

2024-02-06

Recruiting

Psychological Impact of Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation on Donors

NCT06089850Haplo-identical Transplantation, Transplantation

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2024-01-22

Recruiting

Fecal Microbiota Transfer to Improve Diabetes Control Post-bariatric Surgery

NCT06192693Bariatric Surgery, Type 2 Diabetes

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2024-01-21

Recruiting

Dynamics of Resistance Emergence to Azacitidine-based Therapies in Acute Myeloid Leukemia

NCT06225128Acute Myeloid Leukemia

Assistance Publique - Hôpitaux de Paris

Observational

120

Paris

2024-01-16

Recruiting

MoMa Signature During Granulomatosis

NCT05916638Sarcoidosis, Tuberculosis

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2024-01-15

Recruiting

Fecal Transplantation to Eradicate Colonizing Emergent Superbugs

NCT05035342Enterobacteriaceae Infections, Fecal Microbiota Transplantation

DrugFecal Microbiota Transplantation (FMT)

Assistance Publique - Hôpitaux de Paris

Phase 3

214

Clichy, Créteil, Garche, Le Kremlin-Bicêtre, Paris

2024-01-11

Active, closed

Evaluation of an Early Radiomic Signature in Patients With Metastatic Pancreatic Adenocarcinoma Treated With First-line Chemotherapy

NCT07243288Pancreatic Cancer, MeSH Term-Pancreatic Cancer, Adult)

Assistance Publique - Hôpitaux de Paris

Observational

400

Paris

2024-01-09

Recruiting

Self-rehabilitation At Home After LumbaR Arthrodesis (SAHARA)

NCT06129682Spondylolisthesis, Lumbar Region

Assistance Publique - Hôpitaux de Paris

Not applicable

120

Paris

2023-12-18

Recruiting

The Value Electrical Stapedial Reflex Thresholds (eSRTs) Cochlear Implant Mapping

NCT06051006Profound Hearing Loss, Cochlear Implants

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2023-12-07

Recruiting

Qualitative Evaluation of Change Processes in Multifamily Therapy for Adolescents With Anorexia Nervosa

NCT06091306Anorexia Nervosa

Assistance Publique - Hôpitaux de Paris

Observational

138

Paris

2023-12-01

Recruiting

Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People

NCT06138522Post-traumatic Stress Disorder

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2023-11-30

Recruiting

Certolizumab in Recurrent Implantation Failure (RIF)

NCT05930613Recurrent Unexplained Implantation Failure

Assistance Publique - Hôpitaux de Paris

Phase 3

161

Paris

2023-11-30

Recruiting

Development of an Artificial Intelligence Algorithm to Detect Pathological Repolarization Disorders on the ECG and the Risk of Ventricular Arrhythmias

NCT05829993Cardiac Disease, Ventricular Arrythmia

Assistance Publique - Hôpitaux de Paris

Observational

5,000

Paris

2023-11-28

Recruiting

Complex Ocular Infection, Optimization of Microbiological Diagnosis

NCT05432336Endophthalmitis, Keratitis

Assistance Publique - Hôpitaux de Paris

Observational

153

Paris

2023-11-21

Recruiting

Predictive Outcome in Comatose Patients

NCT05321459Coma, Heart Arrest, Cardiopulmonary Resuscitation

Assistance Publique - Hôpitaux de Paris

Observational

100

Bobigny, Paris, Saint-Denis

2023-11-15

Recruiting

Omega Gastric Bypass (150cm) Compared to the Roux-en-Y Gastric Bypass (YOMEGA-2 Multicentric Trial)

NCT06057597Obesity, Morbid

Assistance Publique - Hôpitaux de Paris

Not applicable

368

Paris

2023-11-13

Recruiting

Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome

NCT05726916Hypertensive Emergency-associated Hemolytic Uremic Syndrome

DrugsSoliris·Eculizumab

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2023-11-09

Active, closed

Permanent Intracranial Stenting for Acute Ischemic Stroke Related to a Refractory Large Vessel Occlusion

NCT06071091Acute Ischemic Stroke

Assistance Publique - Hôpitaux de Paris

Not applicable

346

Amiens, Bordeaux, Créteil, Le Kremlin-Bicêtre, Lille, Montpellier, Nancy, Paris

2023-11-08

Recruiting

Uronephrological Complications Risk Factors in Spinal Dysraphism

NCT05718440Spinal Dysraphism

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2023-11-06

Active, closed

First Clinical Evaluation of Heart Transplantation With Grafts Preserved Using an Ex-vivo Extended Perfusion System

NCT06035991Heart Transplantation

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2023-10-28

Active, closed

Effectiveness of the Evaluation and Communication of "Pulmonary Age" as Help for Smoking Cessation

NCT04276116Smoking Cessation

Assistance Publique - Hôpitaux de Paris

Not applicable

101

Paris

2023-10-27

Recruiting

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Versus Valaciclovir

NCT05446571Pregnant Women, CMV Infected Fetuses

DrugsValacyclovir·Letermovir

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2023-10-20

Recruiting

Efficacy and Safety of Obinutuzumab Versus Rituximab in Childhood Steroid Dependant and Frequent Relapsing Nephrotic Syndrome

NCT05786768Steroid-Dependent Nephrotic Syndrome, Steroid-Sensitive Nephrotic Syndrome

Assistance Publique - Hôpitaux de Paris

Phase 2/3

Paris

2023-10-18

Recruiting

Workshops and Exchange Groups for Laryngectomized Patients

NCT06077643Laryngectomy; Status, Laryngeal Cancer

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2023-10-10

Recruiting

Evaluation of the Quality of Life Induced by the Cinnamon Anti-odor Dressing in Patients With Malodorous Wounds

NCT05685628Malodorous Wounds (Chronic, Malignant or Infected Wounds)

Assistance Publique - Hôpitaux de Paris

Not applicable

Vaux-le-Pénil, Créteil, Levallois-Perret, Paris

2023-10-04

Recruiting

Positioning of Molecular Markers in Clinical Routine for the Management of Patients With Adrenal Cancers/Tumors (COMETE-CARE)

NCT05754892Cancer, Adrenal

Assistance Publique - Hôpitaux de Paris

Not applicable

450

Paris

2023-10-01

Recruiting

Motivational Support Program in Chronic Low Back Pain After Multidisciplinary Functional Rehabilitation

NCT05780021Chronic Low-back Pain

Assistance Publique - Hôpitaux de Paris

Not applicable

150

Paris

2023-09-26

Recruiting

Glypican-3 as a Prognostic Factor in Patients With Hepatocellular Carcinoma Treated by Immunotherapy

NCT05263830Hepatocellular Carcinoma

Assistance Publique - Hôpitaux de Paris

Observational

240

Paris

2023-09-08

Recruiting

Vascular Biomarkers Predictive of the Progression From Hypertensive Disorders in Pregnancy to Preeclampsia in Pregnant Women

NCT04520048Hypertension Disorders in Pregnancy, Gestational Hypertension, Pre-Eclampsia

Assistance Publique - Hôpitaux de Paris

Not applicable

110

Bobigny, Bondy, Paris

2023-08-11

Active, closed

Genomic and Metabolomic Markers Reflecting the Complications of Hypercortisolism (CUSHINGOMICS)

NCT04840693Adult Glucocorticoid Excess, Adult Adrenal Insufficiency

DrugBiological samples

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2023-08-01

Recruiting

Melatonin and Response to Lithium

NCT05878730Bipolar Disorder I

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2023-07-26

Recruiting

Brain PERfusion Evaluation by Contrast-Enhanced UltraSound

NCT05893407Cerebral Hemorrhage, Subarachnoid Hemorrhage, Ischemic Stroke, Cerebrovascular Circulation

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2023-07-21

Recruiting

Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE)

NCT05071222Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Paris

2023-07-19

Recruiting

Cerebral Perfusion Variation During Blood Pressure Changes in ICU

NCT05804773Intensive Care Unit Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2023-07-09

Not yet open

Upper Airway Reeducation in Moderate Obstructive Sleep Apnea Syndrome

NCT05911971Moderate Obstructive Sleep Apnea Syndrome

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2023-07

Active, closed

Evaluation of the Use of a Remote Monitoring and Follow-up Option for Patients With Chronic Obstructive Pulmonary Disease (BOREAL)

NCT05759247Chronic Obstructive Pulmonary Disease

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2023-06-19

Recruiting

DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction

NCT05764057AMI, STEMI, NSTEMI, Left Ventricular Dysfunction

Assistance Publique - Hôpitaux de Paris

Phase 3

450

Paris

2023-06-12

Recruiting

Congenital Aniridia Patient Questionnaire

NCT05390801Congenital Aniridia

Assistance Publique - Hôpitaux de Paris

Observational

100

Paris

2023-06-08

Recruiting

Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis

NCT05378841Osteoarthritis Hand

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2023-06-05

Not yet open

Impact of Advanced Practical Nursing Intervention Versus Usual Care on Hypertension Control

NCT05917600Hypertension

Assistance Publique - Hôpitaux de Paris

Not applicable

330

Paris

2023-06

Active, closed

Treatment of Non-ischemic Cardiomyopathies by Intravenous Extracellular Vesicles of Cardiovascular Progenitor Cells

NCT05774509Heart Failure With Reduced Ejection Fraction

Assistance Publique - Hôpitaux de Paris

Phase 1

Paris

2023-05-31

Recruiting

Determinants of Vascular Leakage During Systemic Inflammatory Response Syndrome

NCT05663216Systemic Inflammatory Response Syndrome

Assistance Publique - Hôpitaux de Paris

Observational

180

Paris

2023-05-31

Recruiting

Sexual Dysfunction in Cirrhosis

NCT05428267Sexual Dysfunction in Patients With Cirrhosis Awaiting Liver Transplantation

Assistance Publique - Hôpitaux de Paris

Not applicable

230

Paris

2023-05-26

Recruiting

Sulfasalazine in AML Treated by Intensive Chemotherapy: Elderly Patients-first Line Treatment

NCT05580861Acute Myeloid Leukemia

DrugSulfasalazine

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Amiens, Bobigny, Caen, Créteil, Lyon, Marseille, Nice, Paris

2023-05-17

Recruiting

Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis

NCT05476991Stroke, Stroke, Ischemic, Atherosclerosis, Myocardial Infarction

DrugsAspirin 75·Ticagrelor·Colchicine

Assistance Publique - Hôpitaux de Paris

Phase 3

2,800

Paris

2023-05-17

Recruiting

Treatment of Intra-articular Fractures of the Mandibular Condyle

NCT04776473Intra-articular Fracture of the Mandibular Condyle

Assistance Publique - Hôpitaux de Paris

Not applicable

110

Angers, Annecy, Marseille, Nantes, Paris, Strasbourg, Toulouse

2023-05-03

Recruiting

Multimodal Imaging Signatures of the Biological Mechanisms Underlying Neurodegeneration in Multiple Sclerosis

NCT05633875Multiple Sclerosis (MS)

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2023-04-25

Recruiting

Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB)

NCT05534750Tuberculosis, Multidrug Resistant Tuberculosis

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2023-04-20

Recruiting

Repertoire and Properties of Anti-drug Antibodies Involved in Immediate Hypersensitivity in the Operating Room

NCT05420935Hypersensitivity, Immediate, Peri-operative Injury, Antibiotic Allergy, Antibody Hypersensitivity

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2023-04-12

Recruiting

Rectal Carriage of Carbapenemase Producing-Enterobacteriaceae on Admission to a French University Teaching Hospital

NCT05798351Rectal Carriage of Carbapenemase Producing-Enterobacteriaceae

Assistance Publique - Hôpitaux de Paris

Observational

1,195

Paris

2023-04-03

Active, closed

Evaluation of TNF-alpha Antagonists (Infliximab) Withdrawal in Sarcoidosis

NCT05689879Sarcoidosis

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2023-03-23

Recruiting

3-day IV Antibiotic Treatment Versus 3-day IV Followed by 7-day Oral Antibiotic Treatment for AP in Children

NCT05544565Pyelonephritis Acute

Assistance Publique - Hôpitaux de Paris

Phase 4

480

Corbeil-Essonnes, Orsay, Clamart, Boulogne, Nantes, Lille, Paris, Meaux

2023-03-22

Recruiting

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)

NCT05596539Hypophosphatasia

Assistance Publique - Hôpitaux de Paris

Observational

200

Bordeaux, Lille, Lyon, Nice, Paris, Poitiers, Rennes, Saint-Priest-en-Jarez

2023-03-22

Recruiting

Role of Candidate Proteins in Capillary Leakage During Acute Circulatory Failure

NCT05586282Cardiogenic Shock, Postresuscitation Disease, Septic Shock

Assistance Publique - Hôpitaux de Paris

Observational

380

Paris

2023-03-20

Recruiting

Combination of an Anti-PD1 Antibody With Tisagenlecleucel Reinfusion in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia After Loss of Persistence

NCT05310591B Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, in Relapse

Assistance Publique - Hôpitaux de Paris

Phase 1/2

Bordeaux, Lille, Lyon, Marseille, Montpellier, Nancy, Nantes, Paris

2023-03-15

Recruiting

Angiogenic Biomarkers in Juvenile Idiopathic Arthritis

NCT05534347Juvenile Idiopathic Arthritis (JIA)

DrugBlood sample

Assistance Publique - Hôpitaux de Paris

Observational

300

Paris

2023-03-13

Recruiting

Ultra-protective Ventilation Monitored by Electrical Impedance Tomography in Patients With Severe Acute Respiratory Distress Syndrome on Veno-venous ECMO

NCT05717218Severe ARDS

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2023-03-11

Recruiting

Association Between Tinnitus and Hearing Loss in Locally Advanced Head and Neck Cancer Treated by Radiotherapy Alone or With Chemotherapy: a Prospective and Multicenter Study

NCT05946577Head Cancer, Neck Cancer

Assistance Publique - Hôpitaux de Paris

Observational

140

Paris

2023-03-09

Not yet open

Severe Eosinophilic Asthma Phenotypes During Childhood Have Various Origins

NCT05762627Severe Asthma, Asthma in Children

Assistance Publique - Hôpitaux de Paris

Observational

360

Paris

2023-03

Recruiting

Periodontitis and Inflammation

NCT04831060Periodontitis, Peri-Implantitis

Assistance Publique - Hôpitaux de Paris

Observational

219

Ivry-sur-Seine, Paris

2023-02-15

Active, closed

IBD Disease Course of Infliximab-naïve IBD Patients Treated With Subcutaneous Infliximab CT-P13 Remsima®

NCT05722353Inflammatory Bowel Diseases

Assistance Publique - Hôpitaux de Paris

Not applicable

120

Paris

2023-02-13

Recruiting

Development of New Diagnostic Tools in Capsule Endoscopy

NCT06152289Bowel Disease, Crohn Disease, Celiac Disease, Chronic Diarrhea

Assistance Publique - Hôpitaux de Paris

Observational

10,000

Paris

2023-02-10

Recruiting

Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients

NCT05293197Malignant Brain Tumor, Malignant Glioma, Embryonal Tumor

Assistance Publique - Hôpitaux de Paris

Phase 1

Paris, Villejuif

2023-02-06

Recruiting

Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders

NCT05866991Major Depressive Episode

Assistance Publique - Hôpitaux de Paris

Observational

1,000

Paris

2023-02-01

Recruiting

Multidimensional Characterization of Dyspnea in Children

NCT05500833Dyspnea and Respiratory Insufficiency in Children

Assistance Publique - Hôpitaux de Paris

Observational

400

Paris

2023-01-26

Recruiting

ASL in Brain Metastasis MRI Following Gamma Knife Treatment

NCT04833335Brain Metastases

Assistance Publique - Hôpitaux de Paris

Not applicable

Paris

2023-01-24

Recruiting

DEgenerative ROtator Cuff Disease and Botulinum TOXin

NCT05327972Degenerative Rotator Cuff Disease

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2023-01-20

Active, closed

AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With Lithium

NCT05044611Bipolar Disorder

Assistance Publique - Hôpitaux de Paris

Phase 4

148

Créteil, Paris

2023-01-11

Recruiting

Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta

NCT05419960Osteogenesis Imperfecta

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2022-12-22

Recruiting

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter Trial

NCT05280132Acute Exacerbation of COPD

Assistance Publique - Hôpitaux de Paris

Not applicable

204

Paris

2022-12-08

Recruiting

Biomarkers in Autoimmune Diseases, Vasculitis and Auto Inflammatory Diseases

NCT05383339Autoimmune Diseases, Vasculitis, Autoinflammatory Disease

Assistance Publique - Hôpitaux de Paris

Observational

2,250

Paris

2022-11-29

Active, closed

Impact of a Treatment With Angiotensin Receptor Blocker on Outcome After Acute Kidney Injury in Patients Discharged From the ICU.

NCT05272878Acute Kidney Injury

DrugIrbesartan

Assistance Publique - Hôpitaux de Paris

Phase 3

508

Paris

2022-11-22

Active, closed

Neopterin on Admission to Intensive Care Unit

NCT05233267Elderly Patient (80 Years Old or More) Admitted to Intensive Care

Assistance Publique - Hôpitaux de Paris

Observational

313

Paris

2022-11-21

Recruiting

Follow-up of Patients With Inflammatory Myopathies Associated With a Biobank

NCT05454527Inflammatory Myositis, Idiopathic Inflammatory Myositis, Drug-induced Inflammatory Myositis

Assistance Publique - Hôpitaux de Paris

Observational

4,000

Paris

2022-10-26

Recruiting

Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism Factors

NCT05557201Miscarriage, Early Pregnancy Loss

Assistance Publique - Hôpitaux de Paris

Observational

700

Paris

2022-10-24

Not yet open

Diagnostic Contribution, Prognosis and Physiopathological Aspects in Arrhythmogenic Cardiomyopathy. (ACORE)

NCT05569356Arrhythmogenic Cardiomyopathy

Assistance Publique - Hôpitaux de Paris

Observational

300

Paris

2022-10-20

Recruiting

Use of Crohn's Disease Exclusion Diet on Top of Standard Therapy Versus Standard Therapy Alone in Unstable Pediatric Crohn's Disease Patients.

NCT04777656Crohn's Disease

Assistance Publique - Hôpitaux de Paris

Phase 3

120

Bron, Caen, Marseille, Paris

2022-09-26

Recruiting

Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes

NCT05153070Type 1 Diabetes

DrugCyclosporin

Assistance Publique - Hôpitaux de Paris

Phase 2

Paris

2022-09-21

Recruiting

Albumin and Prognosis of Severely Patients Burns

NCT04264065Severe Burn

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2022-09-16

Recruiting

Research Trial Assessing the Immunogenicity and Safety of Three Meningococcal B Vaccine Strategies Among Patients With Asplenia.

NCT04166656Splenectomy

DrugBexsero

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2022-09-15

Not yet open

Tenecteplase Treatment in Ischemic Stroke Registry

NCT05534360Stroke, Acute

Assistance Publique - Hôpitaux de Paris

Observational

5,000

Paris

2022-09

Not yet open

18FFDG PET/CT for Early Evaluation of Chemotherapy Efficacy in Metastatic Colic Adenocarcinoma

NCT05531045Metastatic Colorectal Cancer

Assistance Publique - Hôpitaux de Paris

Observational

222

Paris

2022-09

Recruiting

Baricitinib in Patients With Relapsing or naïve Dermatomyositis

NCT04972760Dermatomyositis

DrugBaricitinib

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2022-08-31

Recruiting

Exploring Cortical Remyelination in Children With Multiple Sclerosis

NCT05258396Children With Multiple Sclerosis

Assistance Publique - Hôpitaux de Paris

Not applicable

Le Kremlin-Bicêtre, Paris

2022-08-11

Recruiting

Associated Psychiatric Disorders in Children Hospitalized for a Serious Suicide Attempt

NCT05450354Serious Suicide Attempt

Assistance Publique - Hôpitaux de Paris

Observational

200

Paris

2022-08-01

Recruiting

LANdiolol MIcrocirculatory Effects During Septic chOc (MILANOS)

NCT04931225Septic Shock

DrugLandiolol

Assistance Publique - Hôpitaux de Paris

Phase 3

Paris

2022-07-18

Recruiting

Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects

NCT04704089Amelogenesis Imperfecta, Dental Fluoroses, Hypomineralization Molar Incisor

Assistance Publique - Hôpitaux de Paris

Observational

Paris

2022-07-18

Recruiting

The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders

NCT07133789Anomalies Chromosome

Assistance Publique - Hôpitaux de Paris

Observational

105

Paris

2022-07-12

Active, closed

Improve the Survival Without Morbidity of Extremely Preterm Infants (PREMEX)

NCT05248477Newborn, Extreme Prematurity, Pretrm Infants

Assistance Publique - Hôpitaux de Paris

Not applicable

2,377

Paris

2022-06-01

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a French investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 29 October 2026. https://priyalifescience.com/clinical-trials-france/city/paris

Query this register directly

GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in France and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,722 studies in total at the last sync on 29 Oct 2026, 03:20 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 604 of those studies with a site in Paris that also match the filters currently applied.

How many clinical trials are recruiting in Paris?

393 of the 604 studies on this page are recruiting new participants as of the 29 Oct 2026, 03:20 UTC sync. A further 162 have not yet opened recruitment, 49 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Paris), 604 studies
Phase	Studies	Recruiting	Share
Observational	284	199	47%
Not applicable	191	117	31.6%
Phase 3	63	41	10.4%
Phase 2	39	19	6.5%
Phase 1/2	9	7	1.5%
Phase 4	8	5	1.3%
Phase 2/3	7	4	1.2%
Phase 1	3	1	0.5%

Most active sponsors

Lead sponsors with the most studies (Paris)
Lead sponsor	Studies	Recruiting
Assistance Publique - Hôpitaux de Paris	604	393

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.