Reliability of Transcutaneous Bilirubin Measurement According to the Skin Colour of Newborns

Condition(s) studied

Investigational drug(s) / intervention(s)

Skin color assessment: Each participant's skin color is evaluated according to the Fitzpatrick skin type classification. All other care is standard, and no additional treatment is administered.

Study summary

Neonatal jaundice is a physiological process characterized by a yellow coloration of the skin and mucous membranes linked to an increase in a pigment: bilirubin. However, an excessive accumulation of bilirubin can lead to neurological complications: kernicterus. The screening for pathological jaundice is carried out through daily measurements of transcutaneous bilirubin using non-invasive devices (bilirubinometers). The diagnosis is made by measuring blood bilirubin levels and comparing them with reference curves. In newborns with dark skin, transcutaneous bilirubin measurements may be inaccurate because melanin interferes with the bilirubinometers.

Eligibility

Primary outcome measure(s)

• To evaluate the reliability of transcutaneous bilirubin measurements performed routinely with a new-generation bilirubinometer to screen for jaundice according to the degree of skin pigmentation of newborns, determined using a published scale, the Fitzpa — First two days of life
  Based on the first transcutaneous and serum bilirubin assessments

Trial sites (1)

More Assistance Publique - Hôpitaux de Paris trials in France

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