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Clinical Trials in France / NCT05772637
Recruiting Not applicable

Clinical and Urodynamic Assessment of Bladder Sensation in Multiple Sclerosis

NCT05772637 · tracked via the Priya Life Science France tracker
Sponsor
Assistance Publique - Hôpitaux de Paris
Phase
Not applicable
Started
2024-02-14
Last updated
2026-03-05

Condition(s) studied

Overactive Bladder

Investigational drug(s) / intervention(s)

Repeated cystometries with bladder sensations assessment

Repeated cystometries with bladder sensations assessment: A second cystometry will be performed to assess bladder sensations reliability. A third cystometry with cognitive task (STROOP test) at the same time will be performed to assess the impact of distractive attentional task on bladder sensations

Study summary

The aim of the study is to assess the association between bladder sensations progression during bladder filling and severity of Overactive bladder (OAB) in patients with multiple sclerosis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
99 Years
Healthy volunteers
No
Inclusion Criteria: * Age ≥ 18 * MS according to the 2017 Mac Donald diagnostic criteria * Bladder disorders supposedly related to MS * Indication to perform urodynamics * No current medication for bladder disorders * Able to understand and right in French * Affiliated to the "Securite sociale" or "Couverture Medicale Universelle (CMU)", or equivalent organism. Exclusion criteria: * Legal protection * Pregnancy or breastfeeding mother * MS relapse during the past month * Other associated neurological disease * Genuine stress incontinence related to postpartum * Treatment with antimuscarinics, alpha blockers, beta3 adrenergic, or tibial nerve stimulation in the past 15 days, or with botulinic toxin injection in the past 6 months * Previous lower urinary tract surgery * Inability to use the analogic device due to motor, sensory or ataxic disabilities

Primary outcome measure(s)

  • bladder sensation ( area under the sensation-capacity curve (AUC)) — Day 1
    The areas under the sensation-capacity curve (AUC) will be calculated for individual participants using the trapezoidal rule for specific capacity ranges.

Trial sites (1)

FacilityCityRegionStatus
Hôpital TENON Paris Choisir Une Région Recruiting

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Other trials for the same condition

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05772637 on ClinicalTrials.gov ↗ ← All trials in France