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Compound · clinical trials

Bosentan clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 3 trials in our France and Netherlands registers that name Bosentan as an intervention. Synced 26 Sep 2026
3Current trials
1Recruiting now
3Lead sponsors
2Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov registry records · Last verified · Editorial standards
At a glance

Bosentan is named as an intervention in 3 current clinical trials in our France and Netherlands registers. 1 is recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Assistance Publique - Hôpitaux de Paris (1). The most-studied condition is Giant Cell Arteritis (GCA).

Trials by status

  • Recruiting133%
  • Not yet open133%
  • By invitation133%

Trials by phase

  • Phase 2267%
  • Phase 2/3133%
01

Clinical trials of Bosentan

3 trials
StudyPhaseStatusLead sponsorRegisters
Endothelin-1 Receptor Blockade in Resistant Hypertension
NCT04388124 · ClinicalTrials.gov ↗ · Resistant Hypertension
Phase 2 Recruiting University Hospital, Rouen France
Bosentan in the Treatment of Giant Cell Arteritis
NCT06957002 · ClinicalTrials.gov ↗ · Giant Cell Arteritis (GCA)
Phase 2 Not yet open Assistance Publique - Hôpitaux de Paris France
Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm
NCT06432452 · ClinicalTrials.gov ↗ · Coronary Spasm
Phase 2/3 By invitation Radboud University Medical Center Netherlands

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Bosentan across our data

Ireland · EU · US

The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.

Licensed in Ireland (HPRA)

12 single-substance products containing Bosentan on the HPRA medicines list.

  • Bosentan Accord 125 mg film-coated tabletsAccord Healthcare Ireland Ltd. · PA2315/286/002 · Not marketed
  • Bosentan Accord 62.5 mg film-coated tabletsAccord Healthcare Ireland Ltd. · PA2315/286/001 · Not marketed
  • Bosentan Zentiva 125 mg film-coated tabletsZentiva k.s. · PA1701/011/002 · Not marketed
  • Bosentan Zentiva 62.5 mg film-coated tabletsZentiva k.s. · PA1701/011/001 · Not marketed
  • STAYVEER 125 mg film-coated tabletsJanssen Pharmaceutica NV · EU/1/13/832/002
All 12 Irish products →

Supply shortages

No entry for Bosentan in the EMA, FDA or German BfArM shortage lists we track.

03

Conditions studied with Bosentan

3 conditions
Giant Cell Arteritis (GCA)1Resistant Hypertension1Coronary Spasm1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
Assistance Publique - Hôpitaux de Paris1
University Hospital, Rouen1
Radboud University Medical Center1
05

By country register

RegisterTrialsRecruiting
Clinical trials in France21
Clinical trials in Netherlands10

A trial with sites in more than one country appears in each of those registers.

06

Related compounds

07

Questions about Bosentan trials

How many clinical trials are testing Bosentan?

3 current trials in our France and Netherlands registers name Bosentan as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Bosentan trials recruiting patients?

Yes. 1 of the 3 trials is recruiting: 1 with sites in France. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Bosentan clinical trials?

Assistance Publique - Hôpitaux de Paris (1), University Hospital, Rouen (1) and Radboud University Medical Center (1). The number in brackets is how many trials each organisation leads.

Is Bosentan licensed in Ireland?

Yes. The HPRA medicines list includes 12 single-substance products containing Bosentan, for example Bosentan Accord 125 mg film-coated tablets (Accord Healthcare Ireland Ltd.). A licence does not mean a product is currently marketed or reimbursed; see each product's record.

Is there a Bosentan shortage?

Not in the lists we track: Bosentan has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Bosentan works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Bosentan works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Bosentan (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.