Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population

Condition(s) studied

Investigational drug(s) / intervention(s)

urodynamic exam in sitting and lying position: Urodynamic exam with 1st filling in sitting or lying position. Then , during the same procedure, a second filling in the opposite position of the 1st filling (lying or sitting)

Study summary

ICS (International Continence Society) recommendations published in 2017 recommend performing urodynamic examinations in the sitting or standing position. These recommendations are based on a review of the literature published in 2008, which has several limitations: heterogeneous populations, old and non-harmonized techniques, and very few neurological patients. It seems appropriate to focus on neurological patients and to examine the influence of position on the detection of detrusor overactivity in these patients.

The point here is to reexamine the ICS recommendations, which are not designed for neurological patients. Indeed, many patients suffering from Multiple Sclerosis (MS) or Parkinson's disease are unable to sit or stand for the duration of the urodynamic examination. The investigators would like to assess whether exploring sphincter disorders in the supine position is still interpretable.

This would enable us to define ICS good practice recommendations for a neurological population.

Eligibility

Primary outcome measure(s)

• concordance diagnosis of detrusor overactivity between lying and sitting position — 24 months
  Measurement concordance of detrusor pressures using the intraclass correlation coefficient statistic

Trial sites (1)

More Assistance Publique - Hôpitaux de Paris trials in France

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