Ireland
--:--IST
Recruiting Observational

Follow-up of Patients With Inflammatory Myopathies Associated With a Biobank

NCT05454527 · tracked via the Priya Life Science France tracker
Phase
Observational
Started
2022-10-26
Last updated
2025-04-23

Condition(s) studied

Inflammatory MyositisIdiopathic Inflammatory MyositisDrug-induced Inflammatory Myositis

Study summary

Myositis are rare diseases for which the development of a cohort associated with a bank of biological samples (biobank) will allow for the conduct of researches to better delineate the underlying pathophysiology and find cures. This prospective cohort of patients with myositis will allow for identification of factors favouring the occurrence of myositis, whether they are constitutional (genetic) or acquired (environmental or drug). Different subgroups of myositis used for prognostication will be identified based on clinico-demographical variables, the nature of the organs involved beyond peripheral muscles (cardiac, diaphragm) and biomarkers abnormalities

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age ≥ 18 years * Suspicion of Myositis defined according to reference classifications: Dermatomyositis (DM), polymyositis (PM) defined as early as 1975 by Bohan and Peter, inclusion myositis (IM) according to the criteria of Griggs et al, 1995 and autoimmune necrotizing myopathy (ANM) by Hoogendijk et al, in 2004 and iatrogenic (e.g. drug-induced) myositis. * No opposition from patients to the use of their data * Signature of consents for the constitution of the biobank and the genetic analyses Exclusion Criteria: * Patients under AME * Patients under legal protection

Primary outcome measure(s)

  • Characterisation of the different myositis subgroups based on clinical, radiological, electrophysiological and histobiological evaluations — baseline: first 30 days after inclusion
    Characterisation of the different myositis subgroups based on clinical, radiological, electrophysiological and histobiological evaluations

Trial sites (2)

FacilityCityRegionStatus
Département de médecine interne et immunolgie clinique, Hôpital Pitié Salpêtrière Paris France Recruiting
Département de pharmacologie clinique, Hôpital Pitié Salpêtrière Paris France Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05454527 on ClinicalTrials.gov ↗ ← All trials in France