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Clinical Trials in France / NCT07308171
Recruiting Not applicable

Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients

NCT07308171 · tracked via the Priya Life Science France tracker
Sponsor
Assistance Publique - Hôpitaux de Paris
Phase
Not applicable
Started
2026-02-17
Last updated
2026-09-29

Condition(s) studied

Ventilated Patients

Investigational drug(s) / intervention(s)

BaselineInstallation of high flow humidified air cannulaNasal air puffspropeller fan (FAN)

Baseline: patient ventilated through the tracheostomy with initial ventilator settings

Installation of high flow humidified air cannula: Installation of high flow humidified air cannula with inspired oxygen fraction (FiO2) 21%

Nasal air puffs: Nasal air puffs synchronized with the inspiratory time of the ventilator

propeller fan (FAN): Stand-alone fan at the bedside directed toward the face of the patient

Study summary

The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: 1. Age ≥ 18 years 2. Tracheostomy and mechanical ventilation 3. Dyspnea ≥3 4. Consent to participate 5. Affiliation to health insurance Exclusion Criteria: 1. Agitation, delirium 2. Continuous use of sedatives 3. Patients under law protection 4. Inmates 5. Patients without health insurance 6. Breastfeeding and pregnancy

Primary outcome measure(s)

  • Dyspnea — minute 20
    visual analogical scale

Trial sites (1)

FacilityCityRegionStatus
Hôpital Pitié Salpêtrière Paris France Recruiting

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Other trials for the same condition

Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Patients with Chronic Obstructive Bronchopneumopathy. Starting soon
Capillary Refill Time Variation to Predict Oxygen Comsumption Variation After FLuid Challenge (CARTOFL) Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07308171 on ClinicalTrials.gov ↗ ← All trials in France