Clinical trial register · Spain

Clinical Trials in Murcia, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Spain and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5875 matching records held by the registry are in this view. Synced 11 Oct 2026, 03:18 UTC

5875

Studies in scope

all four open statuses

3096

Recruiting now

open to new participants

1137

Lead sponsors

across recruiting studies

Top sites

Barcelona 3238 Madrid 3046 Valencia 1215 Seville 1054 Málaga 746

Trials with a site in Murcia

Status

Study

Lead sponsor

Phase

Enrol

Sites in Spain

Start

Recruiting

A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.

NCT07559175Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF), Pancreatic Enzyme Abnormality, Pancreatic Diseases

DrugZenpep

Aimmune Nestlé Health Science US R&D, LLC

Phase 2

Madrid, Murcia, Lleida, Málaga, Valencia

2026-10

Recruiting

Study to Evaluate the Safety and Preliminary Efficacy of CD19 CAR-T Cell Therapy (TranspoCART19) in Patients With Refractory Lupus Nephritis

NCT07799116Lupus Nephritis, Lupus Nephritis (LN)

Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz

Phase 1/2

Badalona, Santiago de Compostela, Pamplona, León, Madrid, Murcia, Salamanca, Seville

2026-09-23

Recruiting

A Study of Alisertib and Paclitaxel in Patients With Small Cell Lung Cancer (SCLC)

NCT07465757Small Cell Lung Cancer ( SCLC )

DrugsAlisertib·Paclitaxel

Puma Biotechnology, Inc.

Phase 2

Alicante, Barcelona, Logroño, Murcia, San Sebastián de los Reyes, Seville

2026-09-17

Recruiting

Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With Melanoma

NCT07476326Melanoma

DrugOpdivo

Biocon Biologics UK PLC

Phase 1

120

Barcelona, Madrid, Murcia, Sabadell, Seville

2026-09-09

Not yet open

A Precision Medicine Trial for Patients With Relapsed or Refractory T Cell ALL

NCT07522801LAL

DrugsEnrylaze·Tofacitinib·Azacitidine·Venetoclax

Philippe ROUSSELOT

Phase 2

Barcelona, Madrid, Málaga, Murcia, Salamanca, San Sebastián, Santander, Seville

2026-09-01

Recruiting

A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy

NCT07771465Symptomatic Genetic Dilated Cardiomyopathy (DCM)

DrugDanicamtiv

Kardigan, Inc.

Phase 3

332

A Coruña, Barcelona, Madrid, Málaga, Murcia, Palma de Mallorca, Seville

2026-08-26

Recruiting

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

NCT07761117Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)

DrugElecoglipron

AstraZeneca

Phase 3

6,950

Barcelona, Jaén, Madrid, Murcia, Salamanca, Sanlúcar de Barrameda (Cádiz), Seville, Valencia

2026-08-24

Not yet open

Urinary Continence After Vaginal Surgery for Genital Prolapse in the Spanish Population.

NCT07628036Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Urinary Incontinence (UI)

Hospital Universitari Vall d'Hebron Research Institute

Observational

1,042

Barcelona, Santa Coloma de Gramenet, Murcia, Las Palmas de Gran Canaria

2026-08-01

Recruiting

Phase 1/2 Multicenter, Open-label, Dose-escalation Study of IDP- 121 in Patients With Platinum-resistant Small Cell Lung Cancer (MYCrocytic)

NCT07864207Small Cell Lung Cancer ( SCLC )

DrugIDP-121

IDP Discovery Pharma S.L.

Phase 1/2

Barcelona, Las Palmas de Gran Canaria, Madrid, Málaga, Murcia, Pamplona, Santa Cruz de Tenerife, Valencia

2026-07-28

Active, closed

Is Hypoxemia Driving Outcome in Acute Hypoxemic Respiratory Failure? (HOMELAND Study)

NCT07708506Acute Hypoxemic Respiratory Failure

Jesus Villar

Observational

1,241

Barakaldo, Albacete, Barcelona, León, Madrid, Murcia, Valencia, Valladolid

2026-07-13

Recruiting

Effect of the Ultrasound-guided Percutaneous Neuromodulation on the Mean Velocity in Crossfit Practitioners.

NCT07684534Healthy Adult Participants, Crossfit

CEU San Pablo University

Not applicable

Murcia

2026-07-08

Recruiting

Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab

NCT07039422Primary Immune Thrombocytopenia, Warm Autoimmune Hemolytic Anemia

DrugIanalumab

Novartis Pharmaceuticals

Phase 2

Barcelona, Madrid, Murcia

2026-06-26

Recruiting

A Study to Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Whose Current Treatment is Not Working Efficiently

NCT07154745Paroxysmal Nocturnal Hemoglobinuria

DrugsCemdisiran·Pozelimab

Regeneron Pharmaceuticals

Phase 3

Bilbao, Barcelona, Cáceres, Murcia, Salamanca

2026-06-11

Recruiting

Mechanical Insufflation-Exsufflation in Critically Ill Patients

NCT07420946Airway Clearance, Mechanical Insufflation-exsufflation, Mechanical Insufflation-exsufflation Session ( With Cough Assist), Delphi Study

Medipol University

Observational

Murcia

2026-06-10

Recruiting

Human Sperm Cryopreservation as an Alternative to the Decline of Sperm Quality With Aging

NCT07814235Aging, Epigenetic Aging, Infertility, Assisted Reproduction Technologies

IVI Murcia

Observational

Murcia

2026-06-10

Recruiting

Phase III Randomized International Open Label Clinical Trial of Treatment Intensification With Docetaxel Plus Apalutamide in Patients With Metastatic Hormone-sensitive Prostate Cancer Who Did Not Achieve a Deep PSA Response After Initial Treatment With Apalutamide: REINFORCE Trial.

NCT07333066Metastatic Hormone-sensitive Prostate Cancer

DrugsApalutamide (Erleada)·Docetaxel

Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD

Phase 3

320

Zaragoza, Barcelona, L'Hospitalet de Llobregat, Santander, Granada, Santiago de Compostela, Madrid, Murcia

2026-06-05

Not yet open

Masitinib in Patients With Mild Alzheimer's Disease

NCT05564169Alzheimer Disease

DrugMasitinib

AB Science

Phase 3

600

Albacete, Barcelona, Donostia / San Sebastian, Granada, Madrid, Murcia, Pamplona, Zamora

2026-06

Recruiting

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

NCT07124078Chronic Graft-versus-host-disease

DrugAxatilimab

Incyte Corporation

Phase 2

Barcelona, Esplugues de Llobregat, Madrid, Málaga, Murcia, Valencia

2026-05-20

Not yet open

Effects of Resistance Training on Women With Functional Hypothalamic Amenorrhea

NCT07612735Amenorrhea, Functional Hypothalamic Amenorrhea (FHA), Low Energy Availability, Relative Energy Deficiency in Sport

Catholic University of Murcia

Not applicable

Murcia

2026-05-15

Recruiting

Effectiveness of tDCS in Paediatric Amblyopia.

NCT07547670Amblyopia, Amblyopia Strabismic, Visual Acuity, Stereoscopic Vision

Universidad de Murcia

Not applicable

100

Murcia

2026-05-02

By invitation

Effects of Two Intervention Programs on Physical Fitness and Quality of Life Among People With Intellectual Disabilities

NCT07576933Intellectual Disabilities

Universidad Católica San Antonio de Murcia

Not applicable

Murcia

2026-05-01

Recruiting

HOME-AHCL: Home-Based Implementation of an Advanced Hybrid Closed-Loop System With Telemonitoring in Type 1 Diabetes

NCT07492992Diabetes Mellitus Type 1

Air Liquide Healthcare Spain

Observational

Cartagena, Murcia

2026-04-22

Recruiting

Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have Thrombocytopenia

NCT07394153Myelofibrosis，MF

DrugPacritinib

Grupo Español de Enfermedades Mieloproliferativas Crónicas PH Negativas

Phase 2

Barcelona, Jerez de la Frontera, Madrid, Murcia, Salamanca, Valencia

2026-04-15

Not yet open

International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)

NCT07476729B-Cell Acute Lymphoblastic Leukaemia

DrugsInotuzumab Ozogamicin·Blinatumomab

Charite University, Berlin, Germany

Phase 3

750

Murcia

2026-04-01

Recruiting

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

NCT07361510Non-Small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Pembrolizumab

Bristol-Myers Squibb

Phase 3

750

Barcelona, Barakaldo, Jaén, Madrid, Málaga, Murcia

2026-03-12

Recruiting

Effect of Ginger Capsules on Inflammation, Oxidative Stress, and Endothelial Function

NCT07437222Inflammation Biomarkers, Oxidative Stress, Cardiometabolic Risk Factors

Ana Mª Garcia Munoz

Not applicable

Murcia

2026-03-02

Recruiting

Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial

NCT07015892Small Cell Lung Carcinoma

Instituto de Investigación Biomédica de Salamanca

Phase 3

300

Salamanca, Almería, Barakaldo, Girona, Las Palmas de Gran Canaria, Madrid, Murcia, Santander

2026-03-01

Recruiting

Effect of a Ginger-Based Beverage on Inflammation, Oxidative Stress, and Endothelial Function

NCT07433998Inflammation Biomarkers, Oxidative Stress, Cardiometabolic Risk Factors

Javier Marhuenda

Not applicable

Murcia

2026-03

Not yet open

Clinical Trial on a Natural Compound to Improve Chronic Inflammation After SARS-CoV-2 Infection

NCT07397910Long COVID

Universidad Católica San Antonio de Murcia

Not applicable

Murcia

2026-02-23

Recruiting

ShockFast Intravascular Lithotripsy Device for Treatment of Calcified Coronary Lesions

NCT07407738Coronary Arterial Disease, Calcified Coronary Artery Disease

Shunmei Medical

Not applicable

120

Madrid, Murcia, Seville

2026-02-16

Recruiting

"PROTECT-ICU: Impact of an Educational Intervention

NCT07542613Post Intensive Care Syndrome (PICS), Critical Illness

Carola Giménez-Esparza Vich

Not applicable

900

Orihuela, Murcia

2026-02-16

Recruiting

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

NCT07210723Symptomatic Genetic Dilated Cardiomyopathy

DrugDanicamtiv

Kardigan, Inc.

Phase 2/3

332

Horta-Guinardó, Majadahonda, A Coruña, Barcelona, Málaga, Murcia, Palma de Mallorca, Seville

2026-02-13

Recruiting

Registry Study for the Evaluation of High-risk Cardiac Patients by WILLEM AI-based ECG Platform

NCT07333547High-risk Cardiac Patients

Idoven 1903 S.L.

Observational

200,000

Madrid, Murcia

2026-02-03

Recruiting

Xanthigen and Its Impact on Weight and Metabolic Health

NCT07519980Obesity & Overweight

Universidad Católica San Antonio de Murcia

Not applicable

180

Murcia

2026-02-02

Not yet open

Effectiveness of Genistein in Mild Cognitive Impairment

NCT07385937Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)

Universidad Católica San Antonio de Murcia

Not applicable

150

Murcia

2026-02

Recruiting

ReDS-guided Decongestion Strategy in Patients Hospitalized for Heart Failure

NCT07484009Acute Heart Failure (AHF), Heart Failure (for Example, Fluid Overload), Heart Failure Hospitalization

Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal

Not applicable

1,014

Madrid, Barcelona, Córdoba, Girona, Málaga, Murcia, Salamanca, Sant Joan Despí

2026-01-29

Recruiting

Effect of a Nutritional Product Containing Carob Extract on Carbohydrate Metabolism in Glucose-intolerant Subjects

NCT07420998Prediabetes

Universidad Católica San Antonio de Murcia

Not applicable

Murcia

2026-01-26

Recruiting

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

NCT07277231Chronic Lymphocytic Leukemia

DrugsSonrotoclax·Venclyxto·Acalabrutinib·Venclexta

BeOne Medicines

Phase 3

500

Granada, Madrid, Majadahonda, Murcia

2026-01-22

Recruiting

Healthy Effects of Adapted Aikido in People With Grip Disfunction

NCT07391189Unilateral Handgrip Dysfunction

Universidad Católica San Antonio de Murcia

Not applicable

Murcia

2026-01-19

Recruiting

Functional Impact of Acute Respiratory Viral Infections in Older Adults

NCT07388173Respiratory Infections in Old Age

University Hospital, Grenoble

Observational

1,600

Barcelona, Madrid, Murcia

2026-01-15

Recruiting

External Multicenter Validation of the APTTO Model for Prolonged APTT Using Clot Waveform Analysis

NCT07418099Coagulation Disorder, Blood, Prolonged APTT

Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz

Observational

1,500

Leganés, Barcelona, Lleida, Madrid, Murcia, Pamplona, Salamanca, Santiago de Compostela

2026-01-13

Recruiting

Bacterial Diversity Study Using 16S rRNA Sequencing of Periodontal Samples From Patients With Orthodontic Retainers

NCT07718061Fixed Orthodontic Retainer, Orthodontic Appliances, Removable, Orthodontic Appliance Complication, Gingivitis

Universidad de Murcia

Not applicable

Murcia

2026-01-12

Recruiting

PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery.

NCT07550114Surgical Blood Loss, Postoperative Pain, Lumbar Spinal Fusion Surgery

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Not applicable

Barcelona, Murcia

2026-01-08

Not yet open

Evaluating a Liquid Extract of Carob to Improve Blood Sugar in People With Prediabetes

NCT07379931Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)

Universidad Católica San Antonio de Murcia

Not applicable

Murcia

2026-01-01

Recruiting

A Study to Evaluate Adrixetinib (Q702) in Adults With Active Chronic Graft-Versus-Host Disease

NCT07138196Chronic Graft-Versus-Host Disease

DrugAdrixetinib

Qurient Co., Ltd.

Phase 1

Barcelona, Madrid, Majadahonda, Murcia, Pamplona, Santander, Seville, Valencia

2025-12-23

Recruiting

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT07225946Prostatic Neoplasms, Castration-Resistant

DrugsPasritamig·Prednisone/Prednisolone·Docetaxel

Janssen Research & Development, LLC

Phase 3

800

Badalona, Madrid, Murcia, Seville, Valencia, Zaragoza

2025-12-19

Recruiting

Study for Frail Patients With Newly Diagnosed Multiple Myeloma Treated With Daratumumab With Teclistamab or Talquetamab.

NCT07107529Multiple Myeloma (MM)

DrugsTalquetamab·Teclistamab·Daratumumab

European Myeloma Network B.V.

Phase 2

150

Barcelona, Las Palmas, Murcia, Salamanca

2025-12-12

Recruiting

External Validation of the CLOVER Score for Detecting Occult Cancer in Venous Thromboembolism Patients

NCT07310693Venous Thromboembolism (VTE), Occult Cancer

Infanta Leonor University Hospital

Observational

500

Barcelona, Madrid, Murcia, Avilés, Balea

2025-12-01

Recruiting

Safety and Efficacy Evaluation of the iNstroke 4F Thromboaspiration Catheter in Patients With Acute Ischaemic Stroke Due to Primary Distal Medium Vessel Occlusions (DMVO)

NCT07357285Acute Ischemic Stroke

iVascular S.L.U.

Not applicable

Barcelona, Madrid, Murcia

2025-11-27

Not yet open

Standardized Resistance Training Program and Assessment System for Prostate Cancer Patients Receiving Androgen Deprivation Therapy ISPoRT-PCa-ADT Study Protocol for a Randomized Controlled Trial. SPORT-MU

NCT07064811Prostate Cancer

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Not applicable

Murcia

2025-11-15

Recruiting

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

NCT07023627Ovarian Cancer

DrugINCB123667

Incyte Corporation

Phase 2

160

Barcelona, Córdoba, Girona, Madrid, Murcia, Valencia

2025-11-12

Recruiting

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

NCT07085767Breast Cancer, Locally Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer

DrugsPalazestrant·Ribociclib·Letrozole

Olema Pharmaceuticals, Inc.

Phase 3

1,000

Alicante, Barcelona, Granada, León, Lleida, Madrid, Murcia, Seville

2025-11-03

Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

NCT07173751Breast Neoplasms

DrugsEribulin·Pumitamig·Gemcitabine·Carboplatin

BioNTech SE

Phase 3

558

Badajoz, Barcelona, Córdoba, Madrid, Murcia, Pamplona, Sabadell, Valencia

2025-10-30

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment

NCT07007962Immune Thrombocytopenia

DrugRilzabrutinib

Sanofi

Phase 3

Barcelona, Burgos, Madrid, Murcia, San Cristóbal de La Laguna, Seville

2025-10-24

By invitation

Workplace Exercise Therapy With or Without Manual Therapy in Chronic Spinal Pain

NCT07251959Back Pain, Neck Pain, Low Back Pain

Catholic University of Murcia

Not applicable

Murcia

2025-09-29

Recruiting

Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque Psoriasis

NCT07039110Plaque Psoriasis

AbbVie

Observational

700

Málaga, León, Cartagena, El Palmar, Murcia, Pontevedra, Toledo

2025-09-09

Not yet open

Effect of a Probiotic Supplement on Gut Microbiota and Glycemic Control in Patients With Type 1 Diabetes (PRODIAB)

NCT07062224Diabete Type 1

Universidad Católica San Antonio de Murcia

Not applicable

Murcia

2025-09

Recruiting

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

NCT06774131Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma

UroGen Pharma Ltd.

Phase 3

Barcelona, A Coruña, Madrid, Cadiz, Córdoba, Murcia, Seville, Valencia

2025-08-06

Recruiting

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

NCT06721013Immune Thrombocytopenia (ITP)

DrugPirtobrutinib

Eli Lilly and Company

Phase 1/2

Barcelona, Burgos, Murcia, Pamplona

2025-07-30

Recruiting

Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387

NCT07010159Pericarditis, Pericarditis Acute, Recurrent Pericarditis

DrugKPL-387

Kiniksa Pharmaceuticals International, plc

Phase 2/3

325

Barcelona, Madrid, Murcia, Valencia

2025-07-25

Recruiting

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

NCT06943755Pancreatic Neuroendocrine Tumor (pNET), Extra-Pancreatic Neuroendocrine Tumor (epNET)

DrugsZanzalintinib·Everolimus

Exelixis

Phase 2/3

440

Barcelona, Madrid, Murcia, Oviedo, Santander, Santiago de Compostela, Seville, Valencia

2025-07-21

Active, closed

A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

NCT07015983Lupus Erythematosus, Systemic, Lupus Nephritis

DrugsZola-cel·Fludarabine·Cyclophosphamide

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Phase 2

Barcelona, Esplugues de Llobregat, Donostia / San Sebastian, Madrid, Málaga, Murcia

2025-07-14

Active, closed

Support C Post-Market Registry

NCT06678490Coronary Arteriosclerosis

OrbusNeich

Observational

282

Barcelona, Lugo, Madrid, Murcia, Seville

2025-07-09

Not yet open

Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)

NCT06935747Bone Loss, Regenerative Inflammation, Third Molars Extraction

Mario Pérez Sayáns

Phase 4

Santiago de Compostela, Murcia

2025-07

Not yet open

Chronic Intervention With Sulforaphane-Smart® in Overweight and Obese Adults

NCT06964659Obesity and Overweight

Mª Jesús Periago

Early Phase 1

Murcia

2025-07

Recruiting

Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype

NCT06486883Advanced Breast Cancer, Advanced Breast Carcinoma, Hormone Receptor Positive Breast Carcinoma

DrugsCDK4/6i·Trastuzumab deruxtecan

MedSIR

Phase 2

200

Barcelona, Cáceres, Girona, Granada, Jaén, Madrid, Majadahonda, Murcia

2025-06-30

Recruiting

Translation and Validation of the Limbs, Pain, Autonomy, Depression, Anxiety and Quality of Life Scales in Albanian

NCT06685094Musculoskeletal Pain, Autonomy, Healthy, Upper Limb Injury

Universidad Católica San Antonio de Murcia

Observational

300

Murcia

2025-06-30

Recruiting

PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML

NCT06409936CML, Chronic Phase, Chronic Myeloid Leukemia, Chronic Phase, Chronic Myeloid Leukemia, BCR/ABL-Positive, Chronic Myeloid Leukemia

DrugsAsciminib·Nilotinib

Gruppo Italiano Malattie EMatologiche dell'Adulto

Phase 2

160

Barcelona, Bilbao, Girona, Granada, Las Palmas de Gran Canaria, Madrid, Murcia, Salamanca

2025-06-26

Recruiting

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

NCT07098611Ventilator Weaning, Respiration, Artificial, Respiratory Failure, Extubation Readiness

Medipol University

Observational

470

Murcia

2025-06-15

Active, closed

PLUG-IN: Pembrolizumab Combined With Enfortumab Vedotin for Advanced Melanoma Patients

NCT06906822Melanoma

DrugsEnfortumab Vedotin·Pembrolizumab

Grupo Español Multidisciplinar de Melanoma

Phase 2

A Coruña, Badalona, Barcelona, Santander, Madrid, Murcia, Seville, Valencia

2025-06-10

Recruiting

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

NCT07000357Cardiovascular Disease

DrugAZD0780

AstraZeneca

Phase 3

15,100

A Coruña, Alicante, Barcelona, Cáceres, Huelva, Madrid, Málaga, Murcia

2025-06-04

Recruiting

Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.

NCT07432191Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress

Iconic Solutions By Murcia SL

Not applicable

Murcia

2025-05-29

By invitation

Manual Therapy Techniques for Cervical Pain: Algometric Evaluation

NCT06982456Myofascial Pain Syndromes, Massage, Stretching

Universidad de Murcia

Not applicable

105

Murcia

2025-05-19

Not yet open

Predictors of Physical Activity in Adult Patients With Hemophilic Arthropathy

NCT06960499Hemophilia

Universidad Católica San Antonio de Murcia

Observational

Murcia

2025-05-04

Active, closed

Treatment of Patients With Neck Pain After a Commuting Accident

NCT06938828Cervical Injury Spine

Universidad Católica San Antonio de Murcia

Observational

204

Murcia

2025-04-22

Not yet open

Functionality of Lower Limbs in Patients Who Have Undergone Knee Meniscectomy

NCT06920394Meniscectomy Sequelae

Universidad Católica San Antonio de Murcia

Observational

Murcia

2025-04-05

Not yet open

Study to Evaluate the Safety and Efficacy of ARI0002h, for the Initial Treatment of Patients With Primary Plasma Cell Leukaemia

NCT06830733Leukemia, Plasma Cell

Fundacion Clinic per a la Recerca Biomédica

Phase 2

Santander, Madrid, Murcia, Pamplona, Salamanca, Barcelona

2025-04

Recruiting

Comparison of the Effectiveness of Classical Perineal Massage Therapy Versus the Use of an Intravaginal Device to Reduce Postpartum Perineal Pain

NCT06921174Pelvic Pain

Instituto Sexológico Murciano

Phase 2

140

Murcia

2025-03-27

Recruiting

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT06819878Moderately to Severely Active Crohns Disease

DrugAfimkibart

Hoffmann-La Roche

Phase 3

600

Santander, Galdacao, Madrid, Murcia, Valencia, Valladolid

2025-03-17

Active, closed

Blood Flow Restriction in Older Adults

NCT06906523Older Patients

Universidad Católica San Antonio de Murcia

Not applicable

Murcia

2025-03-12

Active, closed

Long Acting Cabotegravir Plus Rilpivirine in People Living With HIV-1 Aged ≥ 60 Years for 24 Months.

NCT06646562HIV-1 Infected Adults With Controlled Viremia

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Phase 4

120

Elche, Villajoyosa, Cartagena, Lorca, Murcia, Pozo-Aledo

2025-03-03

Recruiting

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

NCT06731478Gastric Cancer, Gastroesophageal Junction Cancer

DrugsTrastuzumab deruxtecan·Trastuzumab·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 3

726

Badalona, Barcelona, Córdoba, Elche, L'Hospitalet de Llobregat, Madrid, Málaga, Murcia

2025-02-27

Recruiting

Manual Therapy in Hemophilic Arthropathy of the Ankle

NCT06816056Hemophilia A

Investigación en Hemofilia y Fisioterapia

Not applicable

Murcia

2025-02-05

Recruiting

LEOPARD Training and Validation Data Collection Study

NCT06675604Decompensated Liver Cirrhosis, Primary Biliary Cholangitis, Primary Sclerosing Cholangitis, Hepato-cellular Carcinoma

Assistance Publique - Hôpitaux de Paris

Observational

4,500

Murcia, Seville, Valencia

2025-02-04

Recruiting

An Ex-US Study to Assess Treatment Persistence With Risankizumab in Adult Participants With Psoriatic Arthritis

NCT06764693Psoriatic Arthritis

AbbVie

Observational

1,200

Málaga, Lorca, Vigo, Seville, Granada, Huelva, Madrid, Murcia

2025-01-31

Recruiting

Validity - Reliability of Berg Balance Scale in Albanian Population

NCT06834048Balance Assessment, Balance Control in Elderly, Balance Changes, Geriatric Assessment

Universidad Católica San Antonio de Murcia

Observational

200

Murcia

2025-01-17

By invitation

Effect of Psiguavin for Obesity Treatment (PSIGUAVIN)

NCT06512818Obesity, Overweight or Obesity

Universidad Católica San Antonio de Murcia

Phase 1/2

100

Murcia

2025-01-08

Active, closed

A Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB12 (Proposed Pembrolizumab Biosimilar) to Keytruda® in Non-small Cell Lung Cancer (BENITO Study)

NCT06687369Non Squamous Non Small Cell Lung Cancer

DrugsEU sourced Keytruda·US-sourced Keytruda·Pemetrexed·Cisplatin

mAbxience Research S.L.

Phase 3

726

A Coruña, Barcelona, Madrid, Málaga, Murcia, Oviedo, Palma de Mallorca, Pontevedra

2024-12-30

Recruiting

Clinical Trial to Evaluate the Efficacy of Lacticaseibacillus Rhamnosus CRL1505 in the Prevention of Upper Respiratory Tract Infections in Children

NCT07154992Upper Respiratory Tract Infection, Prevention

Bioithas SL

Not applicable

268

Murcia

2024-12-17

Recruiting

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

NCT06679101Multiple Myeloma, Newly Diagnosed Multiple Myeloma

DrugsBelantamab mafodotin·Daratumumab·Lenalidomide·Dexamethasone

GlaxoSmithKline

Phase 3

520

Badalona, Barcelona, Gijón, Madrid, Málaga, Murcia, Salamanca, Santander

2024-12-16

Recruiting

MEN1703 (SEL24) to Treat Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma (JASPIS-01)

NCT06534437Non-Hodgkin Lymphoma, B-cell

DrugGlofitamab

Ryvu Therapeutics SA

Phase 2

178

Barcelona, Madrid, Murcia, Pamplona, Salamanca, Seville, Zaragoza

2024-12-05

Active, closed

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

NCT06694805HIV Infections

DrugsRpv La·B/F/TAF·Cabotegravir

ViiV Healthcare

Phase 3

326

L'Hospitalet de Llobregat, Bilbao, Puerto Real, Barcelona, Córdoba, Madrid, Málaga, Murcia

2024-12-02

Not yet open

Efficacy of Self-titration of Ventilation in Overlap Syndrome (chronic Obstructive Pulmonar Disease + Sleep Apnea Syndrome ) with Dynamic Hyperinflation. EDIN-IDIN.

NCT06713486Pulmonary Disease, Chronic Obstructive

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Not applicable

Murcia

2024-12-01

By invitation

Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics

NCT06517264Diverticulitis, Colonic

Monica Mengual Ballester

Not applicable

282

Murcia

2024-11-01

Recruiting

International Pilot Study for Dual Non-invasive Assesment of Embryo Development

NCT06524648Infertility

Igenomix

Observational

200

Barcelona, Madrid, Murcia, Seville, Valencia

2024-10-29

Recruiting

A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

NCT06544499Primary Immune Thrombocytopenia (ITP)

DrugEfgartigimod

argenx

Phase 3

A Coruña, L'Hospitalet de Llobregat, Madrid, Murcia, Pozuelo de Alarcón, Valencia

2024-10-18

Recruiting

Diagnostic HER2DX-guided Treatment for Patients wIth Early-stage HER2-positive Breast Cancer

NCT06446882HER2-positive Breast Cancer, Early-stage Breast Cancer

Fundacio Clinic Barcelona

Not applicable

304

L'Hospitalet de Llobregat, Granada, Santiago de Compostela, León, Madrid, Murcia, Reus, Bilbao

2024-10-11

Recruiting

Association of Assisted Reproductive Technologies Parameters With the Perinatal Outcome

NCT06918236Fetal Growth Restriction (FGR), Preeclampsia, Stillbirth, Placenta Previa

Aristotle University Of Thessaloniki

Observational

12,084

Santa Cruz de Tenerife, Madrid, Murcia

2024-10-01

Recruiting

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

NCT06140524Monoclonal Gammopathy of Undetermined Significance (MGUS), Smoldering Multiple Myeloma (SMM)

DrugLinvoseltamab

Regeneron Pharmaceuticals

Phase 2

116

Granada, Terrassa, El Palmar, Gijón, Barcelona, Madrid, Murcia

2024-09-16

Recruiting

Sacituzumab govitEcan in THYroid Cancers

NCT06235216Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer

DrugSacituzumab Govitecan

Grupo Espanol de Tumores Neuroendocrinos

Phase 2

Barcelona, Ferrol, Hospitalet de Llobregat (Barcelona), Madrid, Murcia, Oviedo, Santander, Zaragoza

2024-09-13

Recruiting

Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter

NCT06370182Acute Ischemic Stroke From Large Vessel Occlusion

Anaconda Biomed S.L.

Not applicable

327

Barcelona, Madrid, Murcia, Oviedo

2024-09-09

By invitation

Analysis of COMPASsion and Humanisation of Adolescents Facing the End-of-life Processes.

NCT06310434Compassion, Death Anxiety, Adolescent Behavior

Instituto de Salud Carlos III

Observational

1,852

Murcia

2024-09-01

Active, closed

A Study of Obexelimab in Patients With Relapsing Multiple Sclerosis (MoonStone)

NCT06564311Relapsing Multiple Sclerosis

DrugObexelimab

Zenas BioPharma (USA), LLC

Phase 2

Madrid, Málaga, Murcia, Seville, Valencia

2024-08-26

Recruiting

Feasibility of ONCOhabitats for Surgical and Treatment Planning in IDH-Wildtype Glioblastoma (SINUE)

NCT07111195Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

Juan M Garcia-Gomez

Observational

140

Alicante, Barcelona, Murcia, Santa Cruz de Tenerife, Valencia

2024-07-16

Recruiting

Use of Propofol as a Sedative Agent Versus Spinal Analgesia With Bupivacaine in External Cephalic Version

NCT06449430Pregnancy Complications

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Not applicable

270

Murcia

2024-07-06

Recruiting

Colorectal Anastomosis Outcomes Using the Novel Powered Circular Stapler Compared With Manual Circular Staplers.

NCT06578065Colorectal Anastomosis

Fundación para la Investigación del Hospital Clínico de Valencia

Not applicable

540

Sabadell, Madrid, Murcia, Valencia

2024-06-27

Active, closed

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

NCT06411249Systemic Lupus Erythematosus

DrugBelimumab

GlaxoSmithKline

Phase 4

303

Barcelona, Castellon, Córdoba, Murcia, Valladolid, VigoPontevedra, Villajoyosa

2024-06-06

Recruiting

CHOP Plus Mosunetuzumab as First Line in Patients With Richter´s Syndrome: a Phase II Study of the Spanish Group of CLL

NCT06926205Richter Syndrome

DrugMosunetuzumab

GELLC (Grupo Español de Leucemia Linfocítica Crónica)

Phase 2

Barcelona, L'Hospitalet de Llobregat, Santander, Las Palmas de Gran Canaria, Madrid, Murcia, Marbella, Oviedo

2024-05-15

Recruiting

Integrated Approach in Frail Older People with Atrial Fibrillation

NCT06775028Atrial Fibrillation (AF), Hypertension, Coronary Arterial Disease (CAD), Heart Failure

Heart Care Foundation

Not applicable

1,250

Alicante, Cartagena, Cártama, Elche, Málaga, Murcia, Sant Joan d'Alacant, Tarragona

2024-04-11

Active, closed

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

NCT06291376Immunoglobulin A Nephropathy, IgAN

DrugRavulizumab

Alexion Pharmaceuticals, Inc.

Phase 3

584

A Coruña, Alcalá de Henares, Lleida, Madrid, Málaga, Murcia, Oviedo, Seville

2024-03-29

Recruiting

Spanish-Portuguese Thrombotic Thrombocytopenic Purpura Registry

NCT05914441Purpura, Thrombocytopenic

Fundación Española de Hematología y Hemoterapía

Observational

300

Seville, L'Hospitalet de Llobregat, Barcelona, Guadalajara, Madrid, Murcia, Valencia

2024-03-22

Recruiting

Is the 3D-PANC MSP Model Superior to CT for Assessing Response to Neoadjuvant Treatment in PCA Patients?

NCT06582342Adenocarcinoma of the Pancreas

Fundación para la Investigación del Hospital Clínico de Valencia

Observational

Alicante, Badajoz, Barcelona, Candelaria, Castellon, Málaga, Murcia, Palma de Mallorca

2024-03-21

Recruiting

A Clinical Investigation to Evaluate Microwave Imaging Via MammoWave® in a Population-based Screening Program for Early Breast Cancer Detection

NCT06291896Women's Health: Neoplasm of Breast

Umbria Bioengineering Technologies

Not applicable

10,000

Córdoba, Murcia, Toledo

2024-03-15

Active, closed

A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD

NCT05643638Graft Versus Host Disease, Acute

Cynata Therapeutics Limited

Phase 2

Barcelona, Madrid, Murcia, Pamplona

2024-03-04

Recruiting

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

NCT06152575Multiple Myeloma

DrugsElotuzumab·Elranatamab·Carfilzomib·Pomalidomide

Pfizer

Phase 3

492

Badalona, Terrassa, Barakaldo, Barcelona, Murcia, Girona, Valencia, Madrid

2024-02-08

Recruiting

Study of Olverembatinib (HQP1351) in Patients With CML-CP

NCT06423911Chronic Myeloid Leukemia, CML, CML, Chronic Phase

DrugsBosutinib·Olverembatinib

Ascentage Pharma Group Inc.

Phase 3

333

Badalona, Barcelona, Elche, L'Hospitalet de Llobregat, Madrid, Majadahonda, Málaga, Murcia

2024-02-05

Not yet open

First in Human Study of the Infusion of ARI0003 Cells in Relapsed/Refractory to Treatment B-cell Aggressive Lymphoma

NCT06097455Refractory Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma

Fundacion Clinic per a la Recerca Biomédica

Early Phase 1

Santiago de Compostela, Barcelona, Madrid, Murcia, Oviedo, Palma de Mallorca, Salamanca

2024-01-15

Active, closed

Polyphenol Metabolism and Personalized Nutrition in Menopause (PolyPause).

NCT07182370Menopause Related Conditions, Cardiovascular Risk

National Research Council, Spain

Not applicable

Murcia

2024-01-15

Recruiting

Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer

NCT05950945Breast Cancer

DrugTrastuzumab deruxtecan

Daiichi Sankyo

Phase 3

250

Barcelona, Donostia / San Sebastian, Granada, Las Palmas de Gran Canaria, Madrid, Majadahonda, Murcia, Pamplona

2023-12-30

Active, closed

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis

NCT06141486Multiple Sclerosis

DrugFrexalimab

Sanofi

Phase 3

943

Murcia, Barcelona, Barakaldo, L'Hospitalet de Llobregat, Donostia / San Sebastian, Girona, Las Palmas de Gran Canaria, Lleida

2023-12-27

Active, closed

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

NCT06141473Multiple Sclerosis

DrugsCholestyramine·Activated Charcoal·Teriflunomide·Frexalimab

Sanofi

Phase 3

1,655

Murcia, Barcelona, Barakaldo, Las Palmas de Gran Canaria, Pozuelo de Alarcón, Pontevedra, Seville, Córdoba

2023-12-13

Active, closed

A Study to Evaluate the Efficacy and Safety of Ropeginterferon Alfa-2b in Essential Thrombocythaemia Patients

NCT06514807Essential Thrombocythaemia

DrugBesremi

AOP Orphan Pharmaceuticals AG

Phase 3

117

Badalona, Barcelona, Madrid, Murcia

2023-12-04

Recruiting

Molecular Study of the Maternal-fetal Interface in Preeclampsia.

NCT06232668Preeclampsia

Carlos Simon Foundation

Observational

2,084

Alicante, Murcia, Santa Cruz de Tenerife, Valencia

2023-11-20

Recruiting

Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation

NCT05665608Sudden Cardiac Death, Myocardial Infarction

Charite University, Berlin, Germany

Not applicable

3,595

Alicante, Madrid, Murcia

2023-11-16

Active, closed

Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease

NCT06075706Steroid-refractory Acute Graft-versus-host Disease

DrugMC0518

medac GmbH

Phase 2

Madrid, Pamplona, Barcelona, Málaga, Murcia, Valencia

2023-11-13

Recruiting

Oral Pooled Fecal Microbiotherapy to Prevent Allogeneic Hematopoietic Cell Transplantation Complications (PHOEBUS Trial)

NCT05762211Transplant Complication

DrugPooled allogeneic fecal microbiotherapy

MaaT Pharma

Phase 2

387

Barcelona, Granada, Madrid, Majadahonda, Murcia, Pamplona, Salamanca, Santander

2023-10-31

Recruiting

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

NCT06084936Lymphoma

DrugsGlofitamab·Bendamustine·Tocilizumab·Obinutuzumab

Hoffmann-La Roche

Phase 3

182

Cadiz, A Coruña, Barcelona, Murcia

2023-10-22

Recruiting

Multicenter Study on the Correction of Prolapse Via Laparoscopy

NCT06815731Pelvic Floor Disorders

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Not applicable

181

Murcia

2023-10-01

Recruiting

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)

NCT06114004Sarcoma,Soft Tissue

DrugsSelinexor·Gemcitabine

Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas

Phase 2

Santa Cruz de Tenerife, Barcelona, Donostia / San Sebastian, Madrid, Murcia, Valencia, Zaragoza

2023-09-28

Active, closed

Teclistamab-Daratumumab and Talquestamab-Daratumumab in Newly Diagnosed High-risk Multiple Myeloma

NCT05849610High-Risk de Novo Multiple Myeloma

DrugsTalquetamab·Teclistamab·Bortezomib·Daratumumab

PETHEMA Foundation

Phase 2

Badalona, Barcelona, Madrid, Murcia, Pamplona, Salamanca, Santander, Santiago de Compostela

2023-09-21

Active, closed

Effectivenness and Implementation of an Intervention to Improve Primary Care Patient Safety

NCT05958108Patient Safety

Fundació d'investigació Sanitària de les Illes Balears

Phase 3

110

Granada, Palma de Mallorca, Barcelona, Madrid, Murcia, Salamanca, Pontevedra, Zaragoza

2023-09-01

Active, closed

A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

NCT06081894Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

DrugAficamten

Cytokinetics

Phase 3

500

A Coruña, Barcelona, Madrid, Málaga, Murcia, Palma de Mallorca, Salamanca, Seville

2023-08-31

Recruiting

Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA)

NCT05898399Advanced Solid Tumor, Metastatic Solid Tumor

DrugOlaparib

Artios Pharma Ltd

Phase 1/2

181

Granada, Valladolid, Barcelona, Cáceres, San Carlos, Cadiz, Madrid, Murcia

2023-06-30

Active, closed

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

NCT05827016Multiple Myeloma

DrugsIberdomide·Lenalidomide

Bristol-Myers Squibb

Phase 3

1,230

Barcelona, Cáceres, Las Palmas de Gran Canaria, Murcia, Oviedo, Valencia, Badalona, Madrid

2023-06-22

Recruiting

A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy

NCT05646862Breast Cancer

DrugsBupropion·Omeprazole·Alpelisib·Inavolisib

Hoffmann-La Roche

Phase 3

420

L'Hospitalet de Llobregat, Santiago de Compostela, San Cristóbal de La Laguna, Barcelona, Cáceres, Madrid, Málaga, Murcia

2023-06-07

Recruiting

A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies

NCT05908409Multiple Myeloma (MM), Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Double Hit Lymphoma, High Grade B-Cell Lymphoma, Not Otherwise Specified

DrugIDP-121

IDP Discovery Pharma S.L.

Phase 1/2

Santander, Salamanca, Barcelona, Madrid, Murcia, Seville, Valencia, Zaragoza

2023-06-05

Active, closed

A Real-life Study of the Use of Cabotegravir Plus Rilpivirine Long-acting in ART-experienced Pre-treated People With HIV

NCT06518408Human Immunodeficiency Virus

University Hospital Virgen de las Nieves

Observational

287

Granada, Logroño, Murcia, Cadiz, Córdoba, Jaén, Madrid, Palma de Mallorca

2023-06-01

Recruiting

Early Identification and Treatment of Developmental Trochlear Femoral Dysplasia

NCT05081453TROCLEAR DYSPLASIA

Joaquín Moya-Angeler Pérez-Mateos

Not applicable

Murcia

2023-06-01

Recruiting

Three Types of Papilla Incision in Periodontal Surgery

NCT06428149Periodontitis, Periodontal Diseases, Periodontal Pocket

Universidad de Murcia

Not applicable

Murcia

2023-06-01

Active, closed

Phase I/II of LB-100 Plus Doxorubicin vs. Doxorubicin Alone in First Line of Advanced Soft Tissue Sarcomas

NCT05809830Advanced Soft-tissue Sarcoma

DrugsDoxorrubicin·LB-100·Doxorubicin

Grupo Espanol de Investigacion en Sarcomas

Phase 1/2

152

Barcelona, Madrid, Murcia, Valencia

2023-05-29

Recruiting

Usefulness of PET-CT for Invasive Fungal Infection

NCT05688592Invasive Fungal Infections

Puerta de Hierro University Hospital

Observational

224

Majadahonda, Barcelona, Granada, Madrid, Málaga, Murcia, Oviedo, Salamanca

2023-04-27

Recruiting

Creation of a National Multicenter Platform for the Study of Inflammatory Myocardial Disease: Pre-MYO Cohort

NCT06898762Myocarditis Acute, Inflammatory Cardiomyopathy

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Observational

3,000

Murcia

2023-04-09

Recruiting

AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)

NCT05890716Cardiomyopathies, Cardiac Arrest, Cardiac Arrhythmias, Sudden Cardiac Death

Idoven 1903 S.L.

Observational

5,342

Barcelona, Ciudad Real, A Coruña, Madrid, Murcia, Pamplona, Santa Cruz de Tenerife, Valencia

2023-04-04

Active, closed

A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) and Placebo Given With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies

NCT05794906Biochemically Recurrent Prostate Cancer

DrugDarolutamide

Bayer

Phase 3

985

Santiago de Compostela, Santander, Barcelona, Cadiz, Madrid, Málaga, Murcia, Seville

2023-04-03

Active, closed

A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma

NCT05572515Relapsed or Refractory Multiple Myeloma

DrugsTeclistamab·Carfilzomib·Pomalidomide·Bortezomib

Janssen Research & Development, LLC

Phase 3

614

Badalona, Jerez de la Frontera, L'Hospitalet de Llobregat, León, Madrid, Murcia, Oviedo, Palma de Mallorca

2023-03-29

Recruiting

Combined Intraperitoneal Chemotherapy Regimen After Optimal Interval Surgery in Advanced Ovarian Cancer: BICOV-1 (Bidirectional Chemotherapy in Ovarian Cancer)

NCT06902467Ovarian Cancer

Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Not applicable

Murcia

2023-02-27

Active, closed

Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)

NCT05653349Primary Immune Thrombocytopenia (ITP)

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

226

Barcelona, Madrid, Murcia, Salamanca, Seville

2023-02-03

Recruiting

Neoadjuvant Endocrine Therapy +/- the PI3K Inhibitor Inavolisib in HER2+, HR+, PIK3CA Mutant Early Breast Cancer

NCT05306041HER2-positive Breast Cancer

DrugsPhesgo·Inavolisib

GBG Forschungs GmbH

Phase 2

170

Barcelona, Granada, Lleida, Madrid, Murcia, Palma de Mallorca, Santander, Seville

2023-01-02

Recruiting

Free Mucogingival Graft for Isolated Root Coverage

NCT05851248Free Mucogingival Grafts, Gingival Recession, Root Coverage, Periodontal Plastic Surgery

Universidad de Murcia

Not applicable

Murcia

2023-01-02

Active, closed

A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia

NCT05648968Warm Autoimmune Hemolytic Anemia (wAIHA)

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

Barcelona, Murcia

2022-12-30

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

NCT04953910Acute Myeloid Leukemia, Myelodysplastic Syndromes

DrugDecitabine

Taiho Oncology, Inc.

Phase 1

Barcelona, La Rioja, Lleida, Madrid, Murcia, Valencia

2022-12-23

Active, closed

A Study of Daratumumab

NCT05438043Multiple Myeloma

DrugsCarfilzomib·Pomalidomide·Daratumumab·Lenalidomide

Janssen Research & Development, LLC

Phase 3

213

Alcorcón, Badalona, Barcelona, L'Hospitalet de Llobregat, Madrid, Murcia, Pamplona, Pozuelo de Alarcón

2022-12-15

Active, closed

Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1)

NCT05501886Breast Cancer

DrugsGedatolisib·Alpelisib·Palbociclib·Fulvestrant

Celcuity Inc

Phase 3

701

Madrid, Badajoz, Barcelona, Cáceres, Murcia, Santiago de Compostela

2022-12-08

Active, closed

Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia

NCT05325593Primary Immune Thrombocytopenia

DrugsRomiplostim·Dexamethasone

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Phase 3

129

Barcelona, Burgos, A Coruña, Granada, Madrid, Murcia, Málaga, Salamanca

2022-12-02

By invitation

An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

NCT05667493Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

DrugEplontersen

Ionis Pharmaceuticals, Inc.

Phase 3

1,400

Barcelona, Majadahonda, Murcia, Santiago de Compostela

2022-11-30

Active, closed

Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del

NCT05331183Cystic Fibrosis

DrugsELX/TEZ/IVA·Ivacaftor·Elexacaftor/Tezacaftor/Ivacaftor

Vertex Pharmaceuticals Incorporated

Phase 3

297

Barakaldo, Barcelona, Jerez de la Frontera, Madrid, Murcia, Sabadell, Seville, Valencia

2022-11-23

Active, closed

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

NCT05444257Cystic Fibrosis

DrugVNZ/TEZ/D-IVA

Vertex Pharmaceuticals Incorporated

Phase 3

822

Barcelona, Madrid, Murcia, Sabadell, Seville, Valencia

2022-11-08

Recruiting

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

NCT05519085Relapsed or Refractory Multiple Myeloma

DrugsMezigdomide·Velcade·Pomalidomide·Bortezomib

Celgene

Phase 3

810

Palma, Barcelona, Murcia, Marbella, Cáceres, León, Madrid

2022-09-20

Active, closed

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

NCT05306340Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer

DrugsGiredestrant·Tamoxifen·Exemestane·Everolimus

Genentech, Inc.

Phase 3

373

A Coruña, Barcelona, Córdoba, Madrid, Murcia, Valencia

2022-08-03

Active, closed

A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

NCT05133531Paroxysmal Nocturnal Hemoglobinuria

DrugsSoliris·Ultomiris·Cemdisiran·Pozelimab

Regeneron Pharmaceuticals

Phase 3

202

Bilbao, Barcelona, Murcia, Salamanca

2022-08-01

Active, closed

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382286Triple Negative Breast Cancer, PD-L1 Positive

DrugsAbraxane·Sacituzumab Govitecan·Taxol·Nab-paclitaxel

Gilead Sciences

Phase 3

443

A Coruña, Barcelona, Bilbao, Lleida, Madrid, Málaga, Murcia, Santa Cruz de Tenerife

2022-07-25

Active, closed

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382299Triple Negative Breast Cancer, PD-L1 Negative

DrugsAbraxane·Sacituzumab Govitecan·Nab-paclitaxel·Gemcitabine

Gilead Sciences

Phase 3

623

A Coruña, Barcelona, Bilbao, Lleida, Madrid, Murcia, Seville, Valencia

2022-07-20

Recruiting

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery

NCT04918173Congenital Antithrombin Deficiency

Octapharma

Phase 3

Oviedo, Madrid, Murcia, Ourense

2022-07-01

Active, closed

The Left Bundle Cardiac Resynchronization Therapy Trial

NCT05434962Left Bundle-Branch Block, Heart Failure, Impaired Left Ventricular Function

Óscar Cano Pérez

Not applicable

176

Alicante, L'Hospitalet de Llobregat, Granada, Huelva, Madrid, Majadahonda, Murcia, Valencia

2022-06-27

Active, closed

Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

NCT04975997Multiple Myeloma

DrugsIberdomide·Bortezomib·Daratumumab·Dexamethasone

Celgene

Phase 3

939

Pamplona, Barcelona, Cáceres, Córdoba, Madrid, Málaga, Murcia, Oviedo

2022-06-23

Active, closed

SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM

NCT05405166Plasma Cell Myeloma Recurrent

DrugsParacetamol / Acetaminophen·Montelukast·Diphenhydramine·Isatuximab

Sanofi

Phase 3

531

Murcia, Badalona, Santander, Pamplona, Madrid, Salamanca

2022-06-23

Recruiting

Skeletal Muscle-derived Cell Implantation for Treatment of Fecal Incontinence

NCT04976153Fecal Incontinence

Innovacell GmbH

Phase 3

290

Barcelona, Mataró, Murcia, Oviedo

2022-05-11

Recruiting

Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment

NCT05533528Periodontal Pocket, Periodontal Diseases, Periodontal Bone Loss

Universidad de Murcia

Not applicable

Murcia

2022-05-03

Active, closed

A Study of Combination of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Subject With Previously Treated Multiple Myeloma

NCT05028348Multiple Myeloma

DrugsElotuzumab·Selinexor·Pomalidomide·Dexamethasone

European Myeloma Network B.V.

Phase 3

117

Barcelona, Gijón, Girona, Madrid, Murcia, Pamplona, Salamanca, Santander

2022-04-19

Active, closed

MaaT013 As Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients

NCT04769895Acute Graft Versus Host Disease in Intestine, Steroid Refractory GVHD

MaaT Pharma

Phase 3

Barcelona, El Palmar, Granada, Madrid, Murcia, Pamplona, Salamanca, Santander

2022-03-25

Recruiting

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

NCT05128825High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

DrugAzenosertib

K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Phase 2

310

Barcelona, Madrid, Murcia, Valencia

2022-02-17

Active, closed

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOGAD)

NCT05063162Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD)

DrugRozanolixizumab

UCB Biopharma SRL

Phase 3

113

Barcelona, Madrid, Málaga, Murcia, Seville

2022-02-02

Active, closed

A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

NCT05081609Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor, Platinum-resistant Ovarian Cancer

DrugsTrastuzumab emtansine·Trastuzumab·Pembrolizumab

Ascendis Pharma Oncology Division A/S

Phase 1/2

320

Barcelona, L'Hospitalet de Llobregat, Madrid, Málaga, Murcia, Oviedo, Pamplona, Seville

2022-01-11

Active, closed

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)

NCT04770753Non-Transfusion-dependent Alpha-Thalassemia, Non-Transfusion-dependent Beta-Thalassemia

DrugMitapivat

Agios Pharmaceuticals, Inc.

Phase 3

194

Barcelona, Madrid, Murcia, Seville

2021-12-20

Active, closed

Study of Belantamab Mafodotin in Combination With Kd for the Treatment of Relapsed Myeloma Patients, Refractory to Lenalidomide

NCT05060627Relapsed Multiple Myeloma

DrugsBelantamab mafodotin·Carfilzomib·Dexamethasone

PETHEMA Foundation

Phase 1/2

Badalona, Barcelona, L'Hospitalet de Llobregat, Madrid, Murcia, Oviedo, Palma de Mallorca, Pamplona

2021-12-20

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

NCT04953897Acute Myeloid Leukemia, Myelodysplastic Syndromes

DrugDecitabine

Taiho Oncology, Inc.

Phase 1

Barcelona, La Rioja, Lleida, Madrid, Murcia, Valencia

2021-12-15

Active, closed

EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke

NCT05029414Acute Ischemic Stroke

University Hospital, Basel, Switzerland

Not applicable

543

Barcelona, Girona, Madrid, Murcia, Valladolid

2021-12-09

Active, closed

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

NCT04770779Transfusion-dependent Alpha-Thalassemia, Transfusion-dependent Beta-Thalassemia

DrugMitapivat

Agios Pharmaceuticals, Inc.

Phase 3

258

Barcelona, Madrid, Murcia, Seville

2021-11-30

Active, closed

A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular Lymphoma

NCT04712097Relapsed or Refractory Follicular Lymphoma

DrugsMosunetuzumab·Lenalidomide·Rituximab

Hoffmann-La Roche

Phase 3

478

Guipuzcoa, Madrid, Murcia, Seville, Valencia

2021-10-27

Active, closed

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET

NCT05050942Gastro-enteropancreatic Neuroendocrine Tumor

DrugsCAM2029·Octreotide LAR

Camurus AB

Phase 3

332

A Coruña, Barcelona, Elche, Girona, Madrid, Málaga, Murcia, Oviedo

2021-10-22

Recruiting

MYTHS - MYocarditis THerapy With Steroids

NCT05150704Myocarditis Acute

DrugMethylprednisolone

Niguarda Hospital

Phase 3

288

A Coruña, Barcelona, Madrid, Málaga, Murcia

2021-10-07

Active, closed

A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)

NCT04765059Non-small Cell Lung Cancer

DrugCarboplatin

AstraZeneca

Phase 3

Alicante, Barcelona, Córdoba, León, Madrid, Málaga, Murcia, Oviedo

2021-09-12

Active, closed

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

NCT04923893Multiple Myeloma

DrugsCilta-cel·Bortezomib·Lenalidomide·Fludarabine

Janssen Research & Development, LLC

Phase 3

743

Barcelona, L'Hospitalet de Llobregat, Madrid, Murcia, Pamplona, Salamanca, Santander, Seville

2021-08-19

Recruiting

Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients

NCT04844866Diffuse Large B-cell Lymphoma

Miltenyi Biomedicine GmbH

Phase 2

213

Barcelona, Madrid, Murcia, Pamplona, Salamanca

2021-08-18

Active, closed

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

NCT04964934ER-Positive HER2-Negative Breast Cancer

DrugsCamizestrant·Anastrozole·Abemaciclib·Ribociclib

AstraZeneca

Phase 3

315

A Coruña, Badalona, Barcelona, L'Hospitalet de Llobregat, Madrid, Málaga, Murcia, Sant Joan Despí

2021-06-30

Active, closed

A Study of Guselkumab in Participants With Active Psoriatic Arthritis

NCT04882098Arthritis, Psoriatic

DrugGuselkumab

Janssen Research & Development, LLC

Phase 3

1,054

A Coruña, Córdoba, Madrid, Málaga, Móstoles, Murcia, San Sebastián de los Reyes, Santiago de Compostela

2021-06-17

Recruiting

Efficacy and Safety Evaluation of the Treatment of Allergy Against Cupressaceae and Grasses.

NCT04898283Rhinitis, Allergic, Rhinoconjunctivitis, Asthma, Allergic

Drugs10,000 MG01·30,000 MG01

Inmunotek S.L.

Phase 3

180

Valladolid, Tarancón, Alcalá de Henares, Alcorcón, Madrid, Majadahonda, Murcia, Ávila

2021-05-31

Active, closed

Multicenter Clinical Trial Comparing Treatment with Allogeneic Mesenchymal Cells Versus Autologous Mesenchymal Cells and Versus Active Control with Hyaluronic Acid in Patients with Knee Osteoarthritis.

NCT05086939Knee Osteoarthritis

DrugHyaluronic Acid

Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León

Phase 3

124

Barcelona, Madrid, Málaga, Murcia, Pamplona, Salamanca

2021-05-26

Active, closed

Prospective Observational Study of Filgotinib in Subjects With Rheumatoid Arthritis

NCT04871919Rheumatoid Arthritis

DrugFilgotinib

Alfasigma S.p.A.

Observational

1,304

A Coruña, Barcelona, Córdoba, Mérida, Murcia, Palma, Pontevedra, Santa Cruz de Tenerife

2021-05-11

Recruiting

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

NCT04752722Superficial Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ, Non-muscle Invasive Bladder Cancer

DrugPhase 2

enGene, Inc.

Phase 1/2

350

Barbera Del Valles, Barcelona, L'Hospitalet de Llobregat, Madrid, Murcia, Santander

2021-04-22

Active, closed

Rectal Tumor Resection Using the UNI-VEC Multichannel Transanal Access Device

NCT06286956Rectal Polyp, Rectal Polyps, Rectal Lesion, Sessile Colonic Polyp

Vecmedical Spain, S.L.

Not applicable

Barcelona, Terrassa, A Coruña, Lugo, Vigo, Madrid, Murcia, Gijón

2021-04-19

Active, closed

Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2)

NCT04603495Myelofibrosis, Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis

DrugsPelabresib·Ruxolitinib

Novartis Pharmaceuticals

Phase 3

430

Oviedo, Badalona, Barcelona, Cáceres, Las Palmas de Gran Canaria, Madrid, Murcia, Salamanca

2021-04-09

Recruiting

Minimally Invasive Sinus Lift Through the Interradicular Septum

NCT05237570Bone Loss, Bone Loss, Age-related, Atrophy; Alveolar Process, Surgical Procedure, Unspecified

Universidad de Murcia

Not applicable

Murcia

2021-03-02

Active, closed

Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms

NCT04279847Myelofibrosis, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome, Myeloproliferative Neoplasm

DrugRuxolitinib

Incyte Corporation

Phase 1

140

Badalona, Las Palmas de Gran Canaria, Madrid, Murcia, Salamanca

2021-02-23

Recruiting

First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System

NCT04775108Mitral Valve Regurgitation

Epygon

Not applicable

Badalona, Barcelona, Madrid, Murcia, Seville

2021-02-01

Recruiting

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

NCT04634552Hematological Malignancies

DrugTalquetamab

Janssen Research & Development, LLC

Phase 2

510

Badalona, Barcelona, Madrid, Murcia, Pamplona, Pozuelo de Alarcón, Salamanca, Santander

2021-02-01

Active, closed

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)

NCT04548999Multiple Sclerosis

DrugsOcrelizumab·Methylprednisolone

Hoffmann-La Roche

Phase 3

769

Pozuelo de Alarcón, Barcelona, Madrid, Murcia

2020-12-03

Active, closed

"Phase I / II Study on Infusion of Natural Killer Cells After Haploidentical Transplantation in Pediatric Patients"

NCT05304754High-risk Leukemias

Instituto de Investigación Hospital Universitario La Paz

Phase 1/2

Santiago de Compostela, Oviedo, Barcelona, Madrid, Málaga, Murcia, Seville, Valencia

2020-11-30

Active, closed

Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma

NCT04484623Multiple Myeloma

DrugsBelantamab mafodotin·Pomalidomide·Bortezomib·Dexamethasone

GlaxoSmithKline

Phase 3

302

Barcelona, Gijón, L'Hospitalet de Llobrega, Madrid, MOstoles Madrid, Murcia, Palma de Mallorca, PamplonaNavarra

2020-10-01

Recruiting

Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib

NCT03651206Ovarian Carcinosarcoma, Endometrial Carcinosarcoma

DrugNiraparib

ARCAGY/ GINECO GROUP

Phase 2/3

138

Madrid, Murcia, Valencia

2020-07-15

Active, closed

Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

NCT04246047Multiple Myeloma

DrugsBelantamab mafodotin·Bortezomib·Daratumumab·Dexamethasone

GlaxoSmithKline

Phase 3

494

Barcelona, Cáceres, Gijón, L'Hospitalet de Llobrega, Murcia, PamplonaNavarra, Salamanca

2020-05-07

Active, closed

Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer

NCT04050436Cutaneous Squamous Cell Carcinoma, Advanced Cutaneous Squamous Cell Carcinoma, Metastatic Cutaneous Squamous Cell Carcinoma

DrugsVusolimogene Oderparepvec·Cemiplimab

Replimune, Inc.

Phase 2

231

Barcelona, Madrid, Murcia, Pamplona, Valencia

2019-10-08

By invitation

A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)

NCT04093570Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes

DrugDecitabine

Taiho Oncology, Inc.

Phase 2

332

Lleida, Madrid, Murcia, Valencia

2019-09-30

Recruiting

NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration

NCT03997552Periodontitis, Periodontal Diseases, Periodontal Pocket

Universidad de Murcia

Not applicable

Murcia

2019-09-06

Recruiting

Spine Bone Cements Outcomes - Post Market Follow-up

NCT06367582Vertebral Fracture, Compression Fracture, Osteoporotic Fractures

Teknimed

Observational

500

Barcelona, Granada, Murcia, Terrassa, Zafra

2019-09-04

Recruiting

Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects

NCT03997578Periodontitis, Periodontal Bone Loss, Periodontal; Lesion

Universidad de Murcia

Not applicable

Murcia

2019-09-03

Recruiting

A Treatment Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

NCT03911128Leukemia, Acute Lymphoblastic

Mats Heyman

Observational

500

Alicante, Barakaldo, Barcelona, Fuencarral-El Pardo, Madrid, Murcia, Palma de Mallorca, Santander

2019-08-29

Active, closed

A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

NCT03981796Neoplasms

DrugsNiraparib·Dostarlimab·Paclitaxel·Carboplatin

Tesaro, Inc.

Phase 3

785

Barcelona, Donostia / San Sebastian, Madrid, Málaga, Murcia, Valencia

2019-07-18

Active, closed

Inspiris Resilia Durability Registry

NCT03666741Aortic Valve Stenosis

Institut für Pharmakologie und Präventive Medizin

Observational

400

Murcia

2019-04-26

Active, closed

Atezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle Invasive Bladder Cancer Patients

NCT03799835Bladder Cancer

DrugsTecentriq·Atezolizumab

UNICANCER

Phase 3

517

A Coruña, Cadiz, Madrid, Murcia, Santa Cruz de Tenerife

2019-01-17

Recruiting

Understanding the Long-Term Management of Organic Acidemia Patients With CARBAGLU®: A Mixed Methods Approach

NCT04176523Methylmalonic Acidemia, Propionic Acidemia

DrugCarglumic Acid

RECORDATI GROUP

Observational

Barcelona, Bilbao, Madrid, Murcia, Palma de Mallorca, Seville, Zaragoza

2019-01-15

Active, closed

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve

NCT03682536Myelodysplastic Syndromes

DrugsEpoetin Alfa·Luspatercept

Celgene

Phase 3

363

Barcelona, Granada, Madrid, Málaga, Murcia, Ourense, Oviedo, Palma de Mallorca

2019-01-02

Recruiting

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

NCT03567889Melanoma Stage IIIB, Melanoma Stage IIIC, Melanoma Stage IIID

DrugDaromun

Philogen S.p.A.

Phase 3

186

Badalona, Barcelona, Las Palmas de Gran Canaria, Donostia / San Sebastian, Madrid, Málaga, Murcia, Seville

2018-09-20

Active, closed

SELIBORDARA: Selinexor, Bortezomib and Daratumumab in Multiple Myeloma

NCT03589222Refractory Multiple Myeloma

DrugsSelinexor·Bortezomib·Daratumumab·Dexamethasone

PETHEMA Foundation

Phase 2

Badalona, Barcelona, Girona, L'Hospitalet de Llobregat, Madrid, Murcia, Oviedo, Pamplona

2018-07-15

Active, closed

A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastric Cancer.

NCT03504397Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

DrugsZolbetuximab·Folinic acid·Fluorouracil·Oxaliplatin

Astellas Pharma Global Development, Inc.

Phase 3

565

Badalona, Ávila, Alcorcón, Barcelona, Burgos, Madrid, Murcia, Seville

2018-06-21

Active, closed

A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis

NCT03523858Progressive Multiple Sclerosis (PMS)

DrugOcrelizumab

Hoffmann-La Roche

Phase 3

927

Barcelona, Murcia, Valencia

2018-05-28

Recruiting

A Study of BI-1206 in Combination With Rituximab With or Without Acalabrutinib in Subjects With Indolent B-Cell NHL

NCT03571568Indolent B-Cell Non-Hodgkin Lymphoma

DrugsRuxience·Acalabrutinib·Rituximab

BioInvent International AB

Phase 1/2

140

Badalona, Barcelona, Madrid, Murcia, Seville

2018-05-16

Active, closed

A Study to Investigate the Clinical Benefit of Isatuximab in Combination With Bortezomib, Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

NCT03319667Plasma Cell Myeloma

DrugsVelcade·Isatuximab·Bortezomib·Lenalidomide

Sanofi

Phase 3

475

Barcelona, Madrid, Murcia

2017-12-07

Active, closed

Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)

NCT03767348Non-Small Cell Lung Cancer (NSCLC), Microsatellite Instability-High (MSI-H), Non-melanoma Skin Cancer (NMSC), Cutaneous Melanoma

DrugsVusolimogene Oderparepvec·Opdivo·Nivolumab

Replimune, Inc.

Phase 2

340

Barcelona, Madrid, Murcia, Pamplona, Seville, Valencia

2017-09-20

Active, closed

A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis

NCT03165734Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis

DrugPacritinib

Swedish Orphan Biovitrum

Phase 3

407

Barcelona, Madrid, Murcia, Salamanca, Seville, Valencia

2017-06-26

Active, closed

Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer

NCT02947685HER-2 Positive Breast Cancer, Estrogen Receptor Positive Breast Cancer

DrugsPerjeta·Herceptin·Exemestane·Anastrozole

Alliance Foundation Trials, LLC.

Phase 3

518

Barcelona, Madrid, Málaga, Murcia, Navarro, Salamanca, Santiago, Seville

2017-06-21

Active, closed

Prospective Registry for Patients Undergoing Surgery for Male Stress Urinary Incontinence

NCT02757274Urinary Incontinence, Stress

European Association of Urology Research Foundation

Observational

1,054

Barcelona, Granada, Madrid, Murcia, San Cristóbal de La Laguna, Valencia

2017-02-22

Recruiting

REtroperitoneal SArcoma Registry: an International Prospective Initiative

NCT03838718Retroperitoneal Sarcoma

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Observational

2,000

Murcia

2016-09-01

Active, closed

Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors

NCT02715284Neoplasms

DrugDostarlimab

Tesaro, Inc.

Phase 1

729

Santiago de Compostela, Barcelona, Girona, Madrid, Málaga, Murcia, Pamplona, Santander

2016-03-07

Active, closed

Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

NCT02375204Germ Cell Tumor, Teratoma, Choriocarcinoma, Germinoma

DrugsPegylated G-CSF·G-Csf·Ifosfamide·CDDP

Alliance for Clinical Trials in Oncology

Phase 3

420

Barcelona, Madrid, Murcia

2015-08-06

Active, closed

Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Participants With High Risk Chronic Lymphocytic Leukemia (CLL)

NCT02477696Chronic Lymphocytic Leukemia

DrugsIbrutinib·Acalabrutinib

Acerta Pharma BV

Phase 3

533

Barcelona, Madrid, Majadahonda, Murcia, Santander

2015-07-28

Active, closed

Carfilzomib in Treatment Patients Under 65 Years With High Risk Smoldering Multiple Myeloma

NCT02415413Smoldering Multiple Myeloma

DrugsMelphalan·Carfilzomib·Lenalidomide·Dexamethasone

PETHEMA Foundation

Phase 2

Barcelona, Madrid, Murcia, Oviedo, Pamplona, Plama de Mallorca, Salamanca, Santa Cruz de Tenerife

2015-05

Active, closed

A Study of Abemaciclib (LY2835219) Combined With Fulvestrant in Women With Hormone Receptor Positive HER2 Negative Breast Cancer

NCT02107703Breast Neoplasms

DrugsAbemaciclib·Fulvestrant

Eli Lilly and Company

Phase 3

669

Elche, Barcelona, Lleida, Madrid, Murcia, Valencia

2014-07-22

Recruiting

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

NCT02071134Parkinson's Disease

Boston Scientific Corporation

Observational

1,500

Barcelona, Madrid, Murcia, Oviedo, Valencia

2014-03-04

Recruiting

Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

NCT01949129Acute Lymphoblastic Leukaemia

DrugsGrafalon·Treosulfan·Thiotepa·Busulfan

St. Anna Kinderkrebsforschung

Phase 2/3

1,800

Barcelona, Málaga, Murcia, Oviedo

2013-04

Active, closed

An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis

NCT01357668Juvenile Idiopathic Arthritis

Bristol-Myers Squibb

Observational

800

Sant Joan Despí, Barcelona, Madrid, Murcia, Valencia

2013-01-30

Recruiting

Meal Timing, Genetics and Weight Loss

NCT02829619Obesity

Universidad de Murcia

Observational

5,788

Murcia

2008-01-01

Active, closed

Psoriasis Longitudinal Assessment and Registry

NCT00508547Psoriasis

Janssen Scientific Affairs, LLC

Observational

20,167

Alcalá de Henares, Bilbao, Granada, Madrid, Majadahonda, Murcia, Salamanca, Santiago de Compostela

2007-06-21

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Spanish investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 13 October 2026. https://priyalifescience.com/clinical-trials-spain/city/murcia

Query this register directly

GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Spain and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,875 studies in total at the last sync on 11 Oct 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 233 of those studies with a site in Murcia.

How many clinical trials are recruiting in Murcia?

125 of the 233 studies on this page are recruiting new participants as of the 11 Oct 2026, 03:18 UTC sync. A further 17 have not yet opened recruitment, 83 are active but closed to new participants, and 8 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Murcia), 233 studies
Phase	Studies	Recruiting	Share
Phase 3	82	28	35.2%
Not applicable	49	33	21%
Observational	41	28	17.6%
Phase 2	33	20	14.2%
Phase 1/2	12	7	5.2%
Phase 1	6	4	2.6%
Phase 2/3	5	5	2.1%
Phase 4	3	0	1.3%
Early Phase 1	2	0	0.9%

Most active sponsors

Lead sponsors with the most studies (Murcia)
Lead sponsor	Studies	Recruiting
Universidad Católica San Antonio de Murcia	15	5
Universidad de Murcia	10	9
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia	7	4
Hoffmann-La Roche	6	3
Janssen Research & Development, LLC	6	2
Sanofi	5	1
AstraZeneca	4	2
GlaxoSmithKline	4	1
Novartis Pharmaceuticals	4	1
PETHEMA Foundation	4	0

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.