A Study to Evaluate Adrixetinib (Q702) in Adults With Active Chronic Graft-Versus-Host Disease

Inclusion Criteria: 1. Subjects who are allogeneic HSCT recipients with moderate or severe active cGVHD requiring systemic immune suppression. 2. Subjects with relapsed or refractory active cGVHD who have progressed after all available standard of care treatments. 3. Subject must have documented progressive disease as defined by the NIH 2014 consensus criteria, in terms of either organ specific algorithm or global assessment, or active, symptomatic cGVHD for which the treating physician believes that a new line of systemic therapy is required. 4. Adequate organ and bone marrow functions. 5. Karnofsky Performance Scale of ≥ 60. Exclusion Criteria: 1. Exposure to CSF1R inhibitor therapy for any indication after allogeneic transplant. 2. Any evidence (histologic, cytogenetic, molecular, hematologic, or mixed) of relapse of the underlying cancer. 3. Diagnosed with another malignancy (other than malignancy for which transplant was performed) within 3 years of enrollment. 4. Female subject who is pregnant or breastfeeding. 5. Active, uncontrolled bacterial, viral, or fungal infections, requiring systemic therapy