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Trackers› Clinical trials› California
Clinical trial register · United States · industry-sponsored

Clinical Trials in California, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9125 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 08 Oct 2026, 03:16 UTC
9125
Studies in scope
industry-sponsored, all four open statuses
4951
Recruiting now
open to new participants
2192
Lead sponsors
across recruiting studies
Top states
California 110 Florida 85 Colorado 52 Georgia 48 Illinois 42
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca232 Eli Lilly and Company151 AbbVie145 Merck Sharp & Dohme LLC127 Pfizer113 Clear sponsor filter
State
California110 Florida85 Colorado52 Georgia48 Illinois42
All 46 states
Target enrolment
to

Trials with a site in California

110 of 9125 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Hoffmann-La Roche
Phase 3
1,600
California, Florida, New York
2026-11-30
Recruiting
Hoffmann-La Roche
Phase 3
2,500
Alabama, California, Florida
2026-09-30
Recruiting
Hoffmann-La Roche
Phase 3
400
California, Georgia, Michigan, Nevada, New Mexico
2026-09-30
Recruiting
Hoffmann-La Roche
Phase 3
600
California, Virginia
2026-09-30
Recruiting
Hoffmann-La Roche
Phase 1/2
5
California
2026-09-08
Recruiting
Hoffmann-La Roche
Phase 1
25
California, Florida
2026-06-29
Recruiting
Hoffmann-La Roche
Phase 3
380
California, Connecticut, District of Columbia, Georgia, North Carolina, Ohio, West Virginia
2026-06-23
Recruiting
Hoffmann-La Roche
Phase 1
30
California, Illinois, Ohio
2026-06-18
Recruiting
Hoffmann-La Roche
Phase 2/3
650
Alabama, Arizona, California, Connecticut, New Jersey, New York, Tennessee, Texas
2026-05-21
Recruiting
Hoffmann-La Roche
Phase 3
360
California, Colorado, Florida, Indiana, Iowa, Michigan, Minnesota, Texas
2026-04-27
Recruiting
Hoffmann-La Roche
Phase 2
80
California, Florida, Minnesota, South Dakota, Wisconsin
2026-04-07
Recruiting
Hoffmann-La Roche
Phase 3
1,600
Alabama, Arizona, California, District of Columbia, Florida, Georgia, Idaho, Louisiana
2026-03-23
Recruiting
Hoffmann-La Roche
Phase 3
2,000
Alabama, Arizona, California, Connecticut, Georgia, Hawaii, Illinois, Kentucky
2026-03-16
Recruiting
Hoffmann-La Roche
Phase 2
100
California, Iowa, New York, Rhode Island, South Carolina
2026-03-11
Recruiting
Hoffmann-La Roche
Phase 2
80
California, Florida, Missouri, New Jersey
2026-02-18
Recruiting
Hoffmann-La Roche
Observational
2,000
California, Indiana, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, Tennessee
2026-02-09
Recruiting
Hoffmann-La Roche
Phase 2
120
California, Florida, Georgia, Michigan, Minnesota, Pennsylvania
2026-01-08
Recruiting
Hoffmann-La Roche
Phase 2
160
Arizona, California, Florida, Illinois, Louisiana, Michigan, New York, Ohio
2025-12-05
Recruiting
Hoffmann-La Roche
Phase 3
900
Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia
2025-11-24
Active, closed
Hoffmann-La Roche
Phase 2
193
California, Colorado, Florida, Maryland, Massachusetts, New York, Tennessee, Washington
2025-11-13
Active, closed
Hoffmann-La Roche
Phase 3
1,060
Arizona, California, Connecticut, Florida, Georgia, Illinois, Massachusetts, Michigan
2025-11-12
Recruiting
Hoffmann-La Roche
Phase 3
600
Alaska, Arizona, California, Colorado, Connecticut, Florida, Georgia, Idaho
2025-10-24
Active, closed
Hoffmann-La Roche
Phase 3
1,101
Alabama, Arizona, California, Florida, Georgia, Hawaii, Illinois, Louisiana
2025-09-17
Recruiting
Hoffmann-La Roche
Phase 2
120
California, Tennessee, West Virginia
2025-09-09
Active, closed
Hoffmann-La Roche
Phase 2
330
Arizona, California, Connecticut, District of Columbia, Florida, Georgia, Illinois, New York
2025-08-19
Recruiting
Hoffmann-La Roche
Phase 3
80,000
Alabama, Arizona, California, Connecticut, Florida, Georgia, Hawaii, Illinois
2025-07-02
Recruiting
Hoffmann-La Roche
Phase 3
75
California, Florida, Kentucky, Minnesota, Missouri, Virginia
2025-06-27
Recruiting
Hoffmann-La Roche
Phase 3
425
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas
2025-05-12
Active, closed
Hoffmann-La Roche
Phase 2
285
Alabama, California, Florida, Georgia, Illinois, New York, North Carolina, Ohio
2025-05-05
Recruiting
Hoffmann-La Roche
Phase 1
405
California, Colorado, Connecticut, Florida, Texas
2025-04-30
Active, closed
Hoffmann-La Roche
Observational
44
California, Minnesota, Missouri
2025-04-29
Active, closed
Hoffmann-La Roche
Phase 1
50
California, Florida, Illinois, Kansas, New York, Pennsylvania, Texas
2025-04-28
Recruiting
Hoffmann-La Roche
Phase 3
450
Arizona, California, Florida, Georgia, Illinois, Kentucky, Maryland, Michigan
2025-04-09
Active, closed
Hoffmann-La Roche
Phase 2
30
Arkansas, California, Georgia, Michigan, Texas, Virginia
2025-04-04
Active, closed
Hoffmann-La Roche
Phase 2
162
California, Florida, Georgia, Indiana, Michigan, Minnesota, New Jersey, New York
2025-04-01
Recruiting
Hoffmann-La Roche
Phase 3
600
Alabama, Arizona, California, Colorado, Florida, Georgia, Idaho, Illinois
2025-03-17
Active, closed
Hoffmann-La Roche
Phase 4
274
California, Florida, Illinois, Massachusetts, Nevada, New Jersey, New Mexico, Tennessee
2025-03-14
Recruiting
Hoffmann-La Roche
Phase 2
130
Alaska, California, Colorado, Florida, Idaho, Illinois, Iowa, Kentucky
2025-03-05
Active, closed
Hoffmann-La Roche
Phase 1
75
California, Florida, Georgia, Maryland, Tennessee
2024-12-17
Active, closed
Hoffmann-La Roche
Phase 3
350
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2024-12-11
Active, closed
Hoffmann-La Roche
Phase 3
338
Arizona, California, Connecticut, Florida, Illinois, Maine, Massachusetts, Michigan
2024-09-23
Active, closed
Hoffmann-La Roche
Phase 3
400
Alabama, California, Colorado, Florida, Georgia, Idaho, Illinois, Indiana
2024-09-17
Recruiting
Hoffmann-La Roche
Phase 4
28
Arkansas, California, Colorado, Florida, Georgia, Michigan, Pennsylvania, Texas
2024-08-14
Active, closed
Hoffmann-La Roche
Phase 3
1,050
Alabama, California, Colorado, District of Columbia, Florida, Georgia, Kentucky, Maine
2023-12-11
Recruiting
Hoffmann-La Roche
Phase 3
182
California, Connecticut, District of Columbia, Florida, Indiana, Iowa, Michigan, Missouri
2023-10-22
Recruiting
Hoffmann-La Roche
Phase 1/2
60
California, District of Columbia, Indiana, Iowa
2023-09-21
Active, closed
Hoffmann-La Roche
Phase 3
1,130
Alaska, California, Colorado, Connecticut, District of Columbia, Florida, Hawaii, Illinois
2023-09-18
Active, closed
Hoffmann-La Roche
Phase 3
687
Arkansas, California, Connecticut, District of Columbia, Florida, Illinois, Kentucky, Louisiana
2023-09-14
Recruiting
Hoffmann-La Roche
Phase 3
230
Arizona, California, District of Columbia, Maryland, Massachusetts, Michigan, Nevada, New Jersey
2023-09-08
Active, closed
Hoffmann-La Roche
Phase 3
459
Alabama, California, Florida, Georgia, Idaho, Illinois, Massachusetts, Nevada
2023-08-08
Active, closed
Hoffmann-La Roche
Phase 2
83
California, New York, North Carolina, South Dakota
2023-07-18
Active, closed
Hoffmann-La Roche
Phase 3
2,000
Alabama, Arizona, California, Florida, Georgia, Illinois, Indiana, Louisiana
2023-06-28
Recruiting
Hoffmann-La Roche
Phase 1/2
320
California, Connecticut, Florida, New York, Texas, Virginia
2023-06-20
Recruiting
Hoffmann-La Roche
Phase 3
420
California, Colorado, Connecticut, Florida, Georgia, Kentucky, Massachusetts, Michigan
2023-06-07
Active, closed
Hoffmann-La Roche
Phase 2
199
Alabama, California, Georgia, Maryland, Tennessee, Texas
2023-04-21
Active, closed
Hoffmann-La Roche
Phase 3
85
California, Florida, Georgia, New Jersey, North Carolina, Utah, Virginia
2023-03-29
Active, closed
Hoffmann-La Roche
Phase 2
51
California, Colorado, Kansas, Maryland
2023-02-07
Active, closed
Hoffmann-La Roche
Phase 2
301
Alabama, Arizona, California, Colorado, District of Columbia, Florida, Illinois, Iowa
2023-02-03
Active, closed
Hoffmann-La Roche
Phase 3
1,290
Alabama, Arizona, California, Florida, Georgia, Indiana, Kentucky, Louisiana
2022-12-29
Active, closed
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
NCT05476926Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Branch Retinal Vein Occlusion
DrugsVabysmo·Faricimab
Hoffmann-La Roche
Observational
6,000
Arizona, California, Florida, Illinois, Kentucky, Maryland, Michigan, Pennsylvania
2022-11-21
Recruiting
Hoffmann-La Roche
Phase 1/2
65
Alabama, California, Maryland, Massachusetts, Missouri, New York, Ohio
2022-11-16
Active, closed
Hoffmann-La Roche
Phase 1
121
California, Colorado, Florida, Illinois, North Carolina, Texas
2022-10-26
Active, closed
Hoffmann-La Roche
Phase 3
122
Alabama, California, Colorado, District of Columbia, Georgia, Maryland, Massachusetts, Minnesota
2022-09-27
Active, closed
Hoffmann-La Roche
Phase 3
132
Alabama, California, Colorado, District of Columbia, Florida, Maryland, Massachusetts, Michigan
2022-08-30
Active, closed
Hoffmann-La Roche
Phase 3
922
Arizona, California, Florida, Maryland, Tennessee, Texas, Washington
2022-07-18
Active, closed
Hoffmann-La Roche
Phase 4
136
California, Florida, Oklahoma
2022-06-20
Active, closed
Hoffmann-La Roche
Phase 3
188
California, Colorado, District of Columbia, Maryland, Massachusetts, Missouri, Ohio, Pennsylvania
2022-05-19
Recruiting
Hoffmann-La Roche
Phase 2
40
California, Colorado, Georgia, Indiana, Louisiana, New Jersey, New York, Ohio
2022-05-12
Active, closed
Hoffmann-La Roche
Phase 3
1,300
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2022-05-03
Active, closed
Hoffmann-La Roche
Phase 3
208
California, Missouri, Texas
2022-04-25
Active, closed
Hoffmann-La Roche
Phase 2
46
California, Iowa, Michigan, Missouri, New Jersey, New York, Texas
2022-03-22
Active, closed
Hoffmann-La Roche
Phase 2
109
California, Nevada
2022-03-01
Active, closed
Hoffmann-La Roche
Phase 3
478
California, Georgia, Indiana, Maryland, Michigan, Missouri, New York, North Carolina
2021-10-27
Active, closed
Hoffmann-La Roche
Phase 3
303
Alabama, Arkansas, California, Florida, Michigan, New York, North Carolina, Ohio
2021-10-26
Recruiting
Hoffmann-La Roche
Phase 1
542
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Louisiana
2021-10-22
Active, closed
Hoffmann-La Roche
Phase 3
83
California, Colorado, Georgia, Missouri, Ohio, Texas
2021-10-22
Active, closed
Hoffmann-La Roche
Phase 2
176
California, Missouri, North Carolina, Ohio, Oklahoma, Texas, Virginia, Washington
2021-10-07
Active, closed
Hoffmann-La Roche
Phase 1/2
42
California, Florida, Michigan, Minnesota, New York, Ohio, Tennessee
2021-09-14
Active, closed
Hoffmann-La Roche
Phase 3
4,170
Alabama, California, Colorado, Connecticut, Florida, Illinois, Kansas, Kentucky
2021-08-27
Active, closed
Hoffmann-La Roche
Phase 1
119
California, Connecticut
2021-08-11
Active, closed
Hoffmann-La Roche
Phase 3
142
California, Colorado, Florida, Iowa, Michigan, Minnesota, New York, Texas
2021-06-25
Recruiting
Hoffmann-La Roche
Phase 1/2
316
California, Massachusetts, New Jersey, North Carolina, Pennsylvania, Tennessee
2021-06-22
Active, closed
Hoffmann-La Roche
Phase 2
586
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Kansas
2021-05-05
Active, closed
Hoffmann-La Roche
Phase 3
1,188
Alabama, California, Florida, Georgia, Iowa, Maine, New Jersey, North Carolina
2021-05-04
Active, closed
Hoffmann-La Roche
Phase 3
751
Alabama, Arizona, California, District of Columbia, Florida, Indiana, Kansas, Massachusetts
2021-03-24
Active, closed
Hoffmann-La Roche
Phase 3
746
Alabama, Arizona, California, Colorado, Florida, Illinois, Indiana, Louisiana
2021-03-17
Active, closed
Hoffmann-La Roche
Phase 3
270
Alabama, California, Florida, Maryland, Massachusetts, Mississippi, New Jersey, New York
2021-02-23
Active, closed
Hoffmann-La Roche
Phase 3
55
Arizona, California, Colorado, Louisiana, Michigan, Washington
2021-02-04
Active, closed
Hoffmann-La Roche
Phase 2
920
Arizona, California, Georgia, Idaho, Illinois, Indiana, Maryland, Michigan
2021-01-18
Active, closed
Hoffmann-La Roche
Phase 3
769
Alabama, Arizona, California, Colorado, Florida, Kentucky, Maryland, Massachusetts
2020-12-03
Active, closed
Hoffmann-La Roche
Phase 3
864
Alabama, Arizona, California, Colorado, Florida, Indiana, Kansas, Louisiana
2020-11-26
Active, closed
Hoffmann-La Roche
Phase 1/2
518
California, Colorado, Connecticut, District of Columbia, Kentucky, Oregon, Tennessee, Texas
2020-11-01
Active, closed
Hoffmann-La Roche
Phase 3
985
Alabama, California, Colorado, Connecticut, District of Columbia, Florida, Indiana, Kansas
2020-10-26
Active, closed
Hoffmann-La Roche
Phase 3
992
California, Colorado, Florida, Hawaii, Maryland, Massachusetts, Missouri, New Jersey
2020-10-09
Active, closed
Hoffmann-La Roche
Phase 1/2
210
Arizona, California, Massachusetts, Michigan, North Carolina, Texas
2020-09-03
Active, closed
Hoffmann-La Roche
Phase 1/2
237
California, Florida, Kentucky, Louisiana, Michigan, North Carolina, Ohio, Rhode Island
2020-08-12
Active, closed
Hoffmann-La Roche
Phase 3
271
Alabama, California, Colorado, Connecticut, Florida, Georgia, New York, Ohio
2020-08-10
Active, closed
Hoffmann-La Roche
Phase 2/3
325
California, Massachusetts, New York, North Carolina, Tennessee, Texas, Washington
2020-01-29
Active, closed
Hoffmann-La Roche
Phase 3
672
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Iowa
2019-09-30
Active, closed
Hoffmann-La Roche
Phase 1/2
498
California, Missouri, Texas
2019-08-13
Active, closed
Hoffmann-La Roche
Phase 1/2
422
Alabama, California, Colorado, Florida, Michigan, New York, North Carolina, Pennsylvania
2018-09-25
Recruiting
Hoffmann-La Roche
Phase 3
1,000
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Iowa
2018-09-20
Active, closed
Hoffmann-La Roche
Phase 3
927
California, Florida, Illinois, Massachusetts, Michigan, Missouri, New York, Ohio
2018-05-28
Recruiting
Hoffmann-La Roche
Phase 1/2
1,132
California, Colorado, Florida, Illinois, Minnesota, Nevada, New Jersey, New York
2018-03-30
Active, closed
Hoffmann-La Roche
Phase 2/3
1,000
California, Colorado, Florida, Kentucky, Nevada, New Hampshire, New York, Oregon
2017-09-22
Active, closed
Hoffmann-La Roche
Phase 3
382
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2017-09-20
Active, closed
Hoffmann-La Roche
Phase 2
316
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Kansas
2017-06-27
Active, closed
Hoffmann-La Roche
Phase 1/2
69
California, Colorado, Georgia, Illinois, Maryland, Massachusetts, Missouri, New York
2016-05-03
Active, closed
Hoffmann-La Roche
Phase 2
534
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2015-11-19
Active, closed
Hoffmann-La Roche
Phase 1/2
24
California, Ohio, Pennsylvania
2015-04-01
Rows per page Showing 1–110 of 110
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 8 October 2026. https://priyalifescience.com/clinical-trials-usa/state/california

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,125 studies in total at the last sync on 08 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 110 of those studies with a site in California that also match the filters currently applied.

How many clinical trials are recruiting in California?

40 of the 110 studies on this page are recruiting new participants as of the 08 Oct 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 70 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (California), 110 studies
PhaseStudiesRecruitingShare
Phase 3551950%
Phase 224821.8%
Phase 1/214612.7%
Phase 1847.3%
Observational312.7%
Phase 2/3312.7%
Phase 4312.7%

Most active sponsors

Lead sponsors with the most studies (California)
Lead sponsorStudiesRecruiting
Hoffmann-La Roche11040
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.