RO7795081: RO7795081 will be taken orally once daily (QD), according to the randomized dosing regimen, during the 30-week treatment period.
Semaglutide: Semaglutide 14 mg will be taken orally QD, with up-titration as per label, during the 30-week treatment period.
Placebo: Placebo will be taken orally QD during the 30-week treatment period.
This multicenter, randomized, double-blind, placebo- and open-label active comparator-controlled, parallel-group, dose-range-finding, Phase II study aims to evaluate the efficacy, tolerability, and safety of RO7795081 for glycemic control in adult participants with Type 2 diabetes mellitus (T2D).
| Facility | City | Region | Status |
|---|---|---|---|
| Arizona Liver Health - Tucson | Tucson | Arizona | |
| Orange County Research Center | Lake Forest | California | |
| Prospective Research Innovations Inc. | Rancho Cucamonga | California | |
| Encompass Clinical Research | Spring Valley | California | |
| Chase Medical Research | Waterbury | Connecticut | |
| Emerson Clinical Research Institute | Washington D.C. | District of Columbia | |
| K2 Medical Research South Orlando, LLC | Clermont | Florida | |
| Center for Diabetes, Obesity and Metabolism Inc | Pembroke Pines | Florida | |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | |
| Accellacare of Duly Health and Care | Oak Lawn | Illinois | |
| Mercury Street Medical Group, PLLC | Butte | Montana | |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | |
| Accellacare of Piedmont Healthcare | Statesville | North Carolina | |
| Accellacare of Wilmington, LLC | Wilmington | North Carolina | |
| NexGen Research | Lima | Ohio | |
| Tristar Clinical Investigations | Philadelphia | Pennsylvania | |
| Alliance for Multispecialty Research. LLC | Knoxville | Tennessee | |
| Clinical Research Associates | Nashville | Tennessee | |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | |
| Apex Mobile Clinical Research | Bellaire | Texas | |
| Velocity Clinical Research | Dallas | Texas | |
| Velocity Clinical Research (Impact Research Institute) | Waco | Texas | |
| Chrysalis Clinical Research | St. George | Utah | |
| Manassas Clinical Research Center | Manassas | Virginia | |
| Obudai Egeszsegugyi Centrum Kft. | Budapest | Hungary | |
| NZOZ Osteo-Medic s.c. A. Racewicz, J.Supronik | Bialystok | Podlaskie Voivodeship | |
| Centrum Badan Klinicznych PI-House sp. z o.o. | Gdansk | Pomeranian Voivodeship | |
| Centrum Medyczne INTERCOR Sp. z o.o. | Bydgoszcz | Poland | |
| Pro Familia Altera Sp z o.o. | Katowice | Poland | |
| ETG Lublin | Lublin | Poland | |
| Ekamed sp. z o.o. | Lublin | Poland | |
| NZOZ METABOLICA O?rodek Bada? Klinicznych | Tarnów | Poland | |
| ETG Warszawa | Warsaw | Poland | |
| Centrum Badan Klinicznych | Wroclaw | Poland | |
| ETG Zamosc | Zamość | Poland | |
| Universidad de Sevilla - Hospital Universitario Virgen Macarena | Seville | Barcelona | |
| Instituto De Investigacion Marques De Valdecilla (IDIVAL) | Santander | Cantabria | |
| Hospital Vithas Nisa Sevilla | Castilleja de la Cuesta | Granada | |
| Hospital Universitario A Coruna | A Coruña | LA Coruna | |
| Complexo Hospitalario Universitario de Ferrol (CHUF) | Ferrol | LA Coruna |
+ 10 more sites — see the full list on the official registry below.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07112872 on ClinicalTrials.gov ↗ ← All trials in the USA