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Trackers› Clinical trials› Homburg
Clinical trial register · Germany

Clinical Trials in Homburg, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5062 matching records held by the registry are in this view. Synced 20 Oct 2026, 03:18 UTC
5062
Studies in scope
all four open statuses
2873
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1586 Hamburg 889 Essen 766 Dresden 716 Heidelberg 627
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Universität des Saarlandes13 AstraZeneca5 BioMarin Pharmaceutical4 Medtronic Vascular4 Bristol-Myers Squibb3
Site location
Berlin1586 Hamburg889 Essen766 Dresden716 Heidelberg627
All 639 locations
Target enrolment
to

Trials with a site in Homburg

98 of 5062 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Not yet open
Alexion Pharmaceuticals, Inc.
Phase 3
1,180
Berlin, Hanover, Münster, Cologne, Homburg, Leipzig, Kiel, Essen
2027-11-23
Not yet open
ESR1Real World Assessment Prevalence Study
NCT07817212HR+/HER2- aBC Undergoing 1L Treatment With CDK4/6i (Palbociclib, Abemaciclib or Ribociclib) and AI (Anastrozole or Letrozole)
Institut fuer Frauengesundheit
Not applicable
1,550
Ansbach, Bremen, Celle, Dresden, Düsseldorf, Erlangen, Homburg, Ilsede
2026-10-01
Recruiting
Bristol-Myers Squibb
Phase 2
160
Stuttgart, Marburg, Homburg, Cologne, Haile, Hessen
2026-09-10
Recruiting
Incyte Corporation
Phase 3
426
Aachen, Berlin, Dresden, Freiburg im Breisgau, Halle, Hamburg, Hanover, Homburg
2026-09-08
Not yet open
DKK3 as a Biomarker of Peritoneal Fibrosis in Peritoneal Dialysis Patients
NCT07806708Peritoneal Dialysis (PD), End Stage Renal Disease (ESRD), Peritoneal Fibrosis, Ultrafiltration Failure
Universität des Saarlandes
Observational
30
Homburg
2026-09-01
Not yet open
Mobile Geriatric Unit (MGU) to Reduce Hospitalisations in Nursing Home Residents
NCT07634757Nursing Home Care, Hospitalisation Prevention
Universität des Saarlandes
Observational
4,907
Homburg
2026-09-01
Recruiting
Guerbet
Phase 3
315
Berlin, Bonn, Detmold, Essen, Homburg, Kiel, Lübeck
2026-07-28
Recruiting
B. Braun Melsungen AG
Not applicable
2,184
Homburg
2026-06-17
Active, closed
AstraZeneca
Phase 2
326
Berlin, Cologne, Essen, Hamburg, Heidelberg, Homburg, München, Münster
2026-06-11
Recruiting
Dompé Farmaceutici S.p.A
Phase 3
150
Erlangen, Frankfurt am Main, Marburg, Cologne, Düsseldorf, Homburg, Berlin
2026-06-02
Not yet open
University of Leipzig
Observational
100
Berlin, Frankfurt, Hamburg, Hanover, Heidelberg, Herne, Homburg, Jena
2026-04-01
Recruiting
Insmed Incorporated
Phase 3
344
Heidelberg, Immenhausen, Stuttgart, München, Bonn, Essen, Homburg, Dresden
2026-01-07
Recruiting
Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up
NCT07209852Bradycardia, Atrioventricular Block, Sinus Node Dysfunction, Bundle-Branch Block
Boston Scientific Corporation
Observational
140
Osnabrück, Homburg
2025-12-19
Recruiting
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
NCT06793397Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder, Depression Disorders
DrugCYB003
Cybin IRL Limited
Phase 3
330
Homburg, Berlin, Frankfurt am Main, Mannheim
2025-12-10
Recruiting
Time-restricted Feeding in MASLD
NCT07530809Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD)
Universität des Saarlandes
Not applicable
120
Homburg
2025-10-15
Active, closed
Hoffmann-La Roche
Phase 1
30
Homburg
2025-09-30
Recruiting
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
NCT07115953Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular
Not applicable
130
Homburg, Lübeck, Erlangen, Leipzig, Villingen-Schwenningen
2025-09-22
Recruiting
BioMarin Pharmaceutical
Phase 2
60
Cologne, Homburg, Magdeburg
2025-07-30
Recruiting
Celgene
Phase 3
400
Ulm, Augsburg, Göttingen, Dortmund, Düsseldorf, Münster, Homburg, Erfurt
2025-07-28
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,000
Detmold, Dortmund, Trier, Homburg, Chemnitz
2025-07-21
By invitation
BioMarin Pharmaceutical
Phase 3
140
Homburg, Cologne, Magdeburg
2025-06-20
Recruiting
Digital Solutions for bEtter cAre
NCT07416513Cancer Diagnosis
European Institute of Oncology
Not applicable
200
Homburg
2025-05-14
Recruiting
SPYRAL GEMINI Pilot Study
NCT06907147Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular
Not applicable
175
Erlangen, Homburg
2025-05-01
Recruiting
Sex diffErences in prehoSpitAl Stroke MEdicine
NCT06865950Stroke Acute, Emergency Medical Services, Sex Characteristics, Prehospital Setting
Universität des Saarlandes
Observational
2,000
Homburg
2025-05-01
Not yet open
Long-term Follow-up to Determine Outcome in Liver Disease (LOVE Study)
NCT06907563Steatotic Liver Disease, MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis), Steatotic Liver Disease of Mixed Origin (MetALD), ALD - Alcoholic Liver Disease
Universität des Saarlandes
Observational
30,000
Homburg
2025-04-15
Active, closed
Amgen
Phase 2
252
Berlin, Homburg, Kiel, Würzburg
2025-02-26
Recruiting
A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies
NCT06564038Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma, Mantle-cell Lymphoma, Large B-cell Lymphoma
DrugsSurovatamig·Acalabrutinib·Vincristine·Doxorubicin
AstraZeneca
Phase 1/2
408
Cologne, Homburg, Kiel, Mainz, München, Würzburg
2025-01-30
Active, closed
BioMarin Pharmaceutical
Phase 2
30
Homburg
2024-11-22
Recruiting
Boehringer Ingelheim
Phase 3
1,590
Berlin, Bochum, Cologne, Dresden, Frankfurt, Heidelberg, Homburg, Landshut
2024-11-12
Active, closed
Alnylam Pharmaceuticals
Phase 1/2
89
Homburg
2024-11-07
Recruiting
Novartis Pharmaceuticals
Phase 1/2
232
Regensburg, Dresden, Berlin, Giessen, Greifswald, Heidelberg, Homburg
2024-10-24
Recruiting
BioMarin Pharmaceutical
Phase 2
100
Homburg
2024-10-21
Recruiting
Boehringer Ingelheim
Phase 3
1,800
Berlin, Bochum, Cologne, Dresden, Erlangen, Frankfurt, Heidelberg, Homburg
2024-10-14
Active, closed
Ipsen
Observational
424
Berlin, Frankfurt, Halle, Herne, Homburg, Leipzig
2024-10-14
Recruiting
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
NCT06528314NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis
DrugEfruxifermin
Akero Therapeutics, Inc
Phase 3
2,150
Frankfurt am Main, Homburg, Leipzig, Lübeck, Berlin
2024-10-04
Recruiting
Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)
NCT05947955Acute Respiratory Distress Syndrome, Infections
BioAegis Therapeutics Inc.
Phase 2
600
Homburg, Jena, Munich
2024-10-03
Recruiting
SoniVie Inc.
Not applicable
261
Dresden, Erlangen, Frankfurt, Freiburg im Breisgau, Hamburg, Herne, Homburg, Leipzig
2024-10-03
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
406
Böblingen, Homburg, Berlin, Erbach im Odenwald, Frankfurt am Main
2024-09-26
Recruiting
Sanofi
Phase 3
160
Berlin, Bochum, Bremen, Essen, Göttingen, Hanover, Homburg, Münster
2024-08-21
Active, closed
Janssen Pharmaceutica N.V., Belgium
Phase 2
55
Aachen, Cologne, Homburg, Münster
2024-07-22
Recruiting
Johannes Gutenberg University Mainz
Not applicable
1,354
Homburg, Mainz
2024-07-01
Recruiting
PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC
NCT06102057Stage III Non-small Cell Lung Cancer, Locally Advanced, Unresectable
TheraOp
Phase 2
110
Dresden, Essen, Freiburg im Breisgau, Göttingen, Homburg, Mönchengladbach, München, Oldenburg
2024-07-01
Recruiting
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
NCT06465810Transthyretin Amyloidosis, ATTR-CM, ATTRv-PN, ATTR
AstraZeneca
Observational
1,850
Würzburg, Frankfurt am Main, Hanover, Aachen, Cologne, Mainz, Homburg, Berlin
2024-06-25
Recruiting
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
NCT06419374Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
DrugPegozafermin
89bio, Inc.
Phase 3
762
Chemnitz, Frankfurt, Freiburg im Breisgau, Hanover, Homburg, Münster
2024-05-24
Not yet open
Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)
NCT05587621ST Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction, LDL-cholesterol
Jena University Hospital
Not applicable
300
Jena, Berlin, Dresden, Essen, Frankfurt, Freiburg im Breisgau, Halle, Homburg
2024-04-01
Active, closed
Novo Nordisk A/S
Phase 3
673
Bremen, Dresden, Elsterwerda, Erfurt, Frankfurt, Freiburg im Breisgau, Fulda, Homburg
2024-04-01
Recruiting
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
NCT06318169Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
DrugPegozafermin
89bio, Inc.
Phase 3
1,350
Chemnitz, Frankfurt am Main, Freiburg im Breisgau, Hanover, Homburg, Münster
2024-03-13
Active, closed
Study of ALXN2220 Versus Placebo in Adults With ATTR-CM
NCT06183931Transthyretin Amyloid Cardiomyopathy
DrugCliramitug
Alexion Pharmaceuticals, Inc.
Phase 3
1,181
Berlin, Cologne, Essen, Giessen, Hamburg, Hanover, Heidelberg, Homburg
2024-01-11
Recruiting
Bristol-Myers Squibb
Phase 1/2
460
Münster, Homburg, Leipzig, Berlin, Essen
2023-12-29
Recruiting
Regeneron Pharmaceuticals
Phase 3
904
Stuttgart, Mutlangen, Frankfurt am Main, Essen, Mainz, Homburg, Dresden, Berlin
2023-12-13
Recruiting
Akero Therapeutics, Inc
Phase 3
1,650
Würzburg, Frankfurt am Main, Mainz, Homburg, Leipzig, Lübeck, Berlin
2023-12-01
Recruiting
Universität des Saarlandes
Observational
1,000
Homburg
2023-12-01
Recruiting
Claus Cursiefen
Not applicable
110
München, Cologne, Düsseldorf, Homburg, Berlin, Freiburg im Breisgau, Rostock
2023-11-20
Recruiting
Universität des Saarlandes
Phase 2
43
Augsburg, Erlangen, Regensburg, Mönchengladbach, Homburg
2023-10-06
Recruiting
Fracture Monitor - Femur
NCT05410587Femoral Fracture
AO Innovation Translation Center
Not applicable
37
Homburg, Münster, Tübingen, Ulm
2023-10-03
Recruiting
Gilead Sciences
Phase 3
402
Bayern, Berlin, Homburg, Kiel
2023-09-07
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
1,000
Böblingen, Bayreuth, Erbach im Odenwald, Homburg, Frankfurt am Main
2023-07-11
Recruiting
Global Research Initiative for Patients Screening on MASH
NCT05651724MASH, MASLD, MASH With Fibrosis, Fibrosis, Liver
Julius Clinical
Observational
10,000
Mainz, Homburg
2023-06-30
Active, closed
AbbVie
Phase 1
135
Ulm, Würzburg, Rostock, Homburg, Berlin, Hamburg
2023-06-09
Recruiting
Universität des Saarlandes
Phase 3
330
Homburg, Aschaffenburg, Berlin, Dresden, Giessen, Greifswald, Halle, Karlsruhe
2023-06-07
Active, closed
Universität des Saarlandes
Phase 2
50
Ulm, Augsburg, Erlangen, Regensburg, Frankfurt am Main, Giessen, Düsseldorf, Homburg
2023-05-25
Recruiting
Varian, a Siemens Healthineers Company
Not applicable
132
Stuttgart, Homburg
2023-04-13
Active, closed
AriBio Co., Ltd.
Phase 3
1,535
Aachen, Bad Homburg, Berlin, Günzburg, Homburg, Mannheim
2022-12-23
By invitation
Ionis Pharmaceuticals, Inc.
Phase 3
1,400
Cologne, Heidelberg, Homburg, Münster, Würzburg
2022-11-30
Recruiting
North Karelia Central Hospital
Not applicable
546
Dresden, Homburg
2022-09-01
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
410
Böblingen, Bayreuth, Homburg
2022-08-23
Active, closed
Novo Nordisk A/S
Phase 3
412
Bonn, Erlangen, Frankfurt am Main, Homburg
2022-08-10
Recruiting
A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia
NCT05304377Chronic Myeloid Leukemia, Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Cml
DrugELVN-001
Enliven Therapeutics
Phase 1
250
Aachen, Berlin, Frankfurt, Homburg, Jena, Mannheim, Rostock
2022-05-22
Recruiting
AbbVie
Phase 2
75
Mutlangen, Ulm, Landshut, Munich, Rostock, Cologne, Homburg, Dresden
2022-03-28
Active, closed
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular
Not applicable
1,899
Erlangen, Giessen, Homburg, Leipzig, Lübeck
2021-10-20
Active, closed
AstraZeneca
Phase 3
732
Heidelberg, Homburg, Leipzig, München, Ravensburg
2021-10-18
Active, closed
Inventiva Pharma
Phase 3
1,000
Wiesbaden, Mainz, Homburg, Chemnitz, Dresden, Leipzig, Lübeck, Berlin
2021-08-19
Recruiting
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue (CFS/ME)
NCT03773003Cancer Related Fatigue, Fatigue Syndrome, Chronic
Universität des Saarlandes
Not applicable
150
Homburg
2021-07-20
Active, closed
Plasmafit® Revision Structan® Hip Endoprosthesis Cup
NCT04255966Osteolysis, Arthroplasty Complications, Instability of Prosthetic Joint, Degenerative Osteoarthritis
Aesculap AG
Observational
60
Würzburg, Braunschweig, Bonn, Homburg
2021-04-12
Active, closed
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
NCT04113044Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
AO Innovation Translation Center
Observational
1,500
Berlin, Freiburg im Breisgau, Homburg, Murnau am Staffelsee, Tübingen
2021-02-01
Active, closed
Acerta Pharma BV
Phase 3
611
Bamberg, Berlin, Dresden, Homburg, Neumünster
2020-10-08
Active, closed
German CLL Study Group
Phase 2
42
Augsburg, Cologne, Esslingen am Neckar, Hamm, Homburg, Kiel, Mönchengladbach, Munich
2020-10-01
Recruiting
BioInvent International AB
Phase 1/2
197
Hanover, Heidelberg, Homburg
2020-06-29
Recruiting
CORONA in the Saarland
NCT04837755Covid19
Universität des Saarlandes
Observational
300
Homburg
2020-03-01
Recruiting
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847Movement Disorders, Parkinson Disease, Essential Tremor, Tremor
Abbott Medical Devices
Observational
1,000
Tübingen, Düsseldorf, Münster, Mainz, Homburg, Hamburg
2019-11-26
Active, closed
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors
NCT04082429Haemophilia A Without Inhibitors, Haemophilia B Without Inhibitors
DrugConcizumab
Novo Nordisk A/S
Phase 3
156
Bonn, Homburg
2019-11-13
By invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
NCT03683186PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension
United Therapeutics
Phase 3
1,000
Heidelberg, Greifswald, Mainz, Homburg, Leipzig, Donaueschingen, Dresden, Hamburg
2019-09-23
Active, closed
Madrigal Pharmaceuticals, Inc.
Phase 3
1,759
Berlin, Frankfurt am Main, Homburg, Leipzig, Mainz, Würzburg
2019-03-28
Active, closed
AstraZeneca
Phase 3
724
Dresden, Göttingen, Halle, Hanover, Heidelberg, Homburg, Regensburg, Trier
2019-03-06
Active, closed
Janssen Research & Development, LLC
Phase 3
765
Braunschweig, Duisburg, Homburg, Magdeburg, Münster, Nürtingen
2019-01-25
Active, closed
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
NCT03614260Hypertension, Vascular Diseases, Cardiovascular Diseases
ReCor Medical, Inc.
Not applicable
224
Erlangen, Homburg, Karlsruhe, Konstanz, Leipzig, Lübeck
2018-12-14
Recruiting
Merck Sharp & Dohme LLC
Phase 3
3,500
Tübingen, Erlangen, Munich, Frankfurt am Main, Buxtehude, Hanover, Essen, Homburg
2018-08-21
Active, closed
Bristol-Myers Squibb
Phase 3
545
Aachen, Berlin, Bonn, Cologne, Essen, Frankfurt am Main, Hanover, Homburg
2018-04-18
Active, closed
IRCCS San Raffaele
Observational
1,402
Homburg
2017-01-01
Recruiting
University of Sydney
Phase 4
50,000
Albstadt, Berlin, Bochum, Darmstadt, Elsenfeld, Hechingen, Homburg, Langen
2016-06
Active, closed
ReCor Medical, Inc.
Not applicable
282
Düsseldorf, Erlangen, Freiburg im Breisgau, Homburg, Leipzig, Lübeck, Mainz
2016-03
Recruiting
University Hospital, Geneva
Observational
20,000
Homburg
2015-12-28
Active, closed
Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS)
NCT02215265Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
DrugCisplatin
Lisette Nixon
Phase 3
1,269
Berlin, Giessen, Hamburg, Homburg, Leipzig, Potsdam, Solingen, Ulm
2015-10
Recruiting
Global SYMPLICITY Registry (GSR) DEFINE
NCT01534299Hypertension
Medtronic Vascular
Observational
5,000
Homburg
2012-02
Recruiting
The Homburg Keratoconus Center (HKC)
NCT03923101Keratoconus
Universität des Saarlandes
Observational
5,000
Homburg
2011-01-01
Recruiting
Esteve Pharmaceuticals, S.A.
Observational
500
Erlangen, Heidelberg, Homburg, Magdeburg, Oldenburg
2008-12-09
Active, closed
German Corneal Cross Linking Register
NCT00560651Keratoconus
Suphi Taneri
Observational
356
Homburg, Münster
2007-11
Recruiting
Universität des Saarlandes
Observational
100,000
Homburg
2001-01-01
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Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 20 October 2026. https://priyalifescience.com/clinical-trials-germany/city/homburg

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,062 studies in total at the last sync on 20 Oct 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 98 of those studies with a site in Homburg.

How many clinical trials are recruiting in Homburg?

58 of the 98 studies on this page are recruiting new participants as of the 20 Oct 2026, 03:18 UTC sync. A further 7 have not yet opened recruitment, 30 are active but closed to new participants, and 3 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Homburg), 98 studies
PhaseStudiesRecruitingShare
Phase 3382138.8%
Observational211221.4%
Not applicable171217.3%
Phase 213713.3%
Phase 1/2545.1%
Phase 1313.1%
Phase 4111%

Most active sponsors

Lead sponsors with the most studies (Homburg)
Lead sponsorStudiesRecruiting
Universität des Saarlandes139
AstraZeneca52
BioMarin Pharmaceutical42
Medtronic Vascular43
Bristol-Myers Squibb32
Karuna Therapeutics, Inc., a Bristol Myers Squibb company33
Novo Nordisk A/S30
89bio, Inc.22
AbbVie21
Akero Therapeutics, Inc22
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.