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Trackers› Clinical trials› Aachen
Clinical trial register · Germany

Clinical Trials in Aachen, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5051 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:51 UTC
5051
Studies in scope
all four open statuses
2882
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1584 Hamburg 889 Essen 760 Dresden 707 Heidelberg 627
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Recruitment status
Phase
Lead sponsor
AstraZeneca18 RWTH Aachen University14 Novartis Pharmaceuticals10 Incyte Corporation10 Janssen Research & Development, LLC7
Site location
Berlin1584 Hamburg889 Essen760 Dresden707 Heidelberg627
All 635 locations
Target enrolment
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Trials with a site in Aachen

267 of 5051 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Recruiting
A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia
NCT07623200Essential Thrombocythemia
DrugINCA033989
Incyte Corporation
Phase 3
426
Aachen, Berlin, Dresden, Freiburg im Breisgau, Halle, Hamburg, Hanover, Homburg
2026-09-08
Recruiting
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
NCT07624305Renal Insufficiency, Chronic
DrugsBalcinrenone/dapagliflozin·Dapagliflozin
AstraZeneca
Phase 3
2,800
Aachen, Bad Nenndorf, Berlin, Bonn, Brandenburg an der Havel, Braunschweig, Cloppenburg, Essen
2026-09-01
Not yet open
Shortening Treatment Duration in Uncomplicated Candidemia: the CanTEN Trial
NCT07788586Candidemia, Invasive Candidiasis
Oliver Cornely, MD
Phase 4
420
Aachen, Berlin, Cologne, Dresden, Düsseldorf, Frankfurt am Main, Freiburg im Breisgau, Giessen
2026-09
Recruiting
Adjuvant Trial in Patients With Resected PDAC Randomized to Allocation of Oxaliplatin- or Gemcitabine-based Chemotherapy by Standard Clinical Criteria or by a Transcriptomic Treatment Specific Stratification Signature
NCT05314998Pancreatic Ductal Adenocarcinoma
DrugsFolinic acid·Irinotecan·Adrucil·Capecitabine
John Neoptolemos
Phase 3
394
Aachen, Augsburg, Bochum, Bonn, Deggendorf, Dresden, Erlangen, Frankfurt
2026-08-17
Recruiting
Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country Study
NCT07746895C3 Glomerulopathy (C3G), Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)
DrugPegcetacoplan
Swedish Orphan Biovitrum
Phase 4
150
Aachen, Berlin, Cologne, Dresden, Erlangen, Essen, Hamburg, Hanover
2026-08-05
Not yet open
Prevention Programme for Improvement of Well-being and Level of Participation in Adolescents With Enhanced Psychiatric Burden in the School Environment.
NCT06390384Blended-care Counselling, Digital and Mental Literacy Training, App STEPS
RWTH Aachen University
Not applicable
100
Aachen
2026-08-01
Recruiting
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
NCT07742735Short Bowel Syndrome (SBS), SBS Associated With Intestinal Failure (SBS-IF)
DrugApraglutide
VectivBio AG
Phase 3
124
Heidelberg, Erlangen, Hamburg, Bonn, Essen, Münster, Aachen, Berlin
2026-08
Recruiting
Pridopidine Phase 3 Study in Huntington's Disease
NCT07609108Huntington Disease
DrugPridopidine
Prilenia
Phase 3
400
Aachen, Bochum, Erlangen, Münster, Taufkirchen, Ulm
2026-07-01
Not yet open
Everolimus bAsed caLcineurin inhibiTor frEe immunosuppRession oNe Year AfTer lIver transplantatiON (ALTERNATION)
NCT07739914Liver Allograft, Liver Diseases, Liver Transplantation
DrugsCyclosporine·Tacrolimus·Everolimus
Hannover Medical School
Phase 3
150
Heidelberg, Tübingen, Regensburg, Würzburg, Hamburg, Hanover, Rostock, Aachen
2026-06-30
Recruiting
An Observational Study of Octreotide Subcutaneous Depot in Patients With Acromegaly
NCT07583563Acromegaly
Camurus AB
Observational
200
Aachen, Leipzig, Magdeburg, München, Würzburg
2026-06-05
Recruiting
Safety and Performance of the Novalung Ultimate Kit and Xenios 2.0 During Stationary Use in Hospital and Ground-based Transport of Patients on Extracorporeal Life Support (ECLS)
NCT07156669Cardio-Respiratory Failure, Extracorporeal Membrane Oxygenation Complication, Acute Lung Injury
Xenios AG
Observational
20
Erfurt, Aachen, Solingen
2026-05-19
Recruiting
Study of INCA036978 in Participants With Myeloproliferative Neoplasms
NCT07441694Myeloproliferative Neoplasms
Incyte Corporation
Phase 1
218
Aachen, Berlin, Freiburg im Breisgau, Halle, Mainz
2026-05-11
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001Obesity, Heart Failure
DrugNNC0487-0111
Novo Nordisk A/S
Phase 3
5,610
Aachen, Bad Friedrichshall, Bad Oeynhausen, Berlin, Bochum, Coburg, Cologne, Dresden
2026-05-11
Recruiting
Adjuvant Stereotactic Body Radiation Therapy After Trans-arterial Chemoembolization in Hepatocellular Carcinoma
NCT04996914Hepatocellular Carcinoma Non-resectable
RWTH Aachen University
Not applicable
30
Aachen
2026-05-05
Not yet open
Psychological Stress and Support Needs of Volunteer First Responders After Smartphone-based Cardiac Arrest Alerts
NCT07607808Mental Health, Stress Disorder, Post Traumatic
University Hospital, Aachen
Not applicable
75
Aachen
2026-05-01
Recruiting
Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe
NCT07585890End-stage Liver Disease (ESLD), Acute Liver Failure, Liver Cirrhosis, Liver Transplantation
University Medical Center Groningen
Observational
10,000
Aachen, Essen, Frankfurt, Heidelberg
2026-04-21
Recruiting
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
NCT07472517Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)
DrugsObrixtamig·Etoposide·Atezolizumab·Carboplatin
Boehringer Ingelheim
Phase 3
670
Aachen, Berlin, Berlin-Spandau, Dresden, Essen, Frankfurt, Freiburg im Breisgau, Gauting
2026-04-13
Recruiting
A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer
NCT07405801Breast Cancer
DrugsInavolisib·Ribociclib·Fulvestrant
Hoffmann-La Roche
Phase 2
80
Aachen, Dessau, Essen, Heidelberg, Tübingen
2026-04-07
Recruiting
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
NCT07326709Huntington Disease
DrugVotoplam
Novartis Pharmaceuticals
Phase 3
770
Aachen, Bochum, Münster, Tübingen, Ulm
2026-03-24
Recruiting
Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)
NCT07223814Acute Myeloid Leukemia
DrugsBleximenib·Idarubicin·Daunorubicin·Cytarabine
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
875
Aachen, Bochum, Bonn, Greifswald, Halle, Hanover, Heilbronn, Karlsruhe
2026-03-01
Not yet open
A Study on Remote Health Support for Patients With Heart Failure.
NCT07440472Heart Failure
Universitat Internacional de Catalunya
Observational
90
Aachen
2026-03
Recruiting
Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS
NCT07197944Short Bowel Syndrome
DrugGlepaglutide
Zealand Pharma
Phase 3
90
Rostock, Leipzig, Aachen, Berlin, Bonn, Hamburg
2026-02-11
Recruiting
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
NCT07215702Sepsis, Acute Kidney Injury
DrugAZD4144
AstraZeneca
Phase 2
124
Aachen, Essen, Frankfurt, Greifswald, Heidelberg, Kiel, Leipzig, Münster
2026-02-10
Recruiting
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
NCT07412756Depressive Disorder, Major
DrugBrenipatide
Eli Lilly and Company
Phase 3
1,000
Aachen, Berlin, Bielefeld, Chemnitz, Mainz, Mannheim, Schwerin, Siegen
2026-02-09
Recruiting
Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation
NCT07025824AML - Acute Myeloid Leukemia, MDS (Myelodysplastic Syndrome)
DrugsTreosulfan·Melphalan·Fludarabine
Technische Universität Dresden
Phase 2
220
Aachen, Augsburg, Berlin, Chemnitz, Cologne, Dresden, Frankfurt am Main, Greifswald
2026-01-21
Recruiting
Smoking Cessation Before Bronchoscopy or CT-guided Puncture
NCT07322796Pulmonary Nodule, Solitary, Smoking Behaviors
RWTH Aachen University
Observational
25
Aachen
2026-01-01
Recruiting
Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant Ribociclib
NCT07237256Breast Cancer
UNICANCER
Phase 3
3,902
Aachen, Augsburg, Bad Nauheim, Berlin, Bremen, Cottbus, Dresden, Düsseldorf
2025-12-18
Recruiting
STOP-PKD: SGLT2-inhibition to Improve Prognosis in Polycystic Kidney Disease
NCT07280585Polycystic Kidney, Autosomal Dominant
DrugDapagliflozin
University of Cologne
Phase 3
420
Stuttgart, Nuremberg, Aachen, Berlin, Cologne, Dortmund, Dresden, Düsseldorf
2025-12-16
Recruiting
Development of the PTSD-iMPACT to Measure PTSD-Related Functional Impairment in Children and Adolescents - A Validation Study in Switzerland and Germany
NCT07368166PTSD - Post Traumatic Stress Disorder, PTSD-Related Functional Impairment in Children and Adolescents
University Children's Hospital, Zurich
Observational
1,200
Aachen, Bamberg, Eichstätt, Konstanz, Marburg, Oldenburg, Ulm
2025-12-15
Recruiting
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
NCT07221253Biliary Tract Cancer
DrugsGemcitabine/Cisplatin·Rilvegostomig·Durvalumab
AstraZeneca
Phase 3
1,100
Aachen, Berlin, Bonn, Düsseldorf, Essen, Frankfurt, Freiburg im Breisgau, Hamburg
2025-12-04
Not yet open
Impact of a Physical Activity Intervention on Cardiometabolic Health, Mental Health, and Lifestyle Factors.
NCT07237893Healthy
University of Liege
Not applicable
1,000
Aachen
2025-11-24
Recruiting
Phase II Study Evaluating Ivosidenib Maintenance After SOC Adjuvant Chemotherapy in Curative mIDH1 Cholangiocarcinoma
NCT07260175Cholangiocarcinoma, IDH Mutation
DrugIvosidenib
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Phase 2
40
Aachen, Bonn, Essen, Frankfurt, Giessen, Göttingen, Hamburg, Jena
2025-11-18
Recruiting
Combining Loncastuximab Tesirine and Epcoritamab in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
NCT07197307Aggressive Diffuse Large B-cell Lymphoma, High-grade B-cell Lymphoma (HGBL), Follicular Lymphoma (FL) Grade 3B
Universität Münster
Phase 2
120
Aachen, Augsburg, Berlin, Bielefeld, Chemnitz, Düsseldorf, Erlangen, Essen
2025-10-31
Recruiting
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
NCT07213804Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Neoplasm Metastasis
DrugsMIRV·Pegylated liposomal doxorubicin·Topotecan·Gemcitabine
Eli Lilly and Company
Phase 3
1,630
Aachen, Berlin, Bonn, Cologne, Dresden, Düsseldorf, Erlangen, Essen
2025-10-22
Recruiting
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
NCT07196748Colitis, Ulcerative
DrugIcotrokinra
Janssen Research & Development, LLC
Phase 3
882
Aachen, Berlin, Dachau, Erlangen, Halle, Hanover, Jerichow, Kiel
2025-10-01
Not yet open
Prospective Register Study to Assess Eligibility for and Efficacy of Surgical Treatment in Patients With nEuRovascular Conflict
NCT07135024Trigeminal Neuralgia, Tic Douloureux, Facial Pain, Glossopharyngeal Neuralgia
Gerrit A Schubert
Observational
5,001
Aachen
2025-10-01
Recruiting
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
NCT06865417Ulcerative Colitis
DrugFilgotinib
Alfasigma S.p.A.
Phase 3
80
Aachen, Leipzig, Mainz, Tübingen
2025-09-29
Recruiting
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
NCT07007312Acute Myeloid Leukemia (AML)
DrugsZiftomenib·Venclyxto·Ara-C·Venclexta
Kura Oncology, Inc.
Phase 3
1,300
Bad Saarow, Aachen
2025-09-26
Recruiting
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109High Risk Cardiovascular Disease, Hypertension, High Cardiovascular Risk
DrugZilebesiran
Alnylam Pharmaceuticals
Phase 3
11,000
Aachen, Ahaus, Altenburg, Bad Homburg, Berlin, Brandenburg an der Havel, Bremen, Cologne
2025-09-22
Active, closed
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
NCT07169578Alzheimers Disease
DrugTrontinemab
Hoffmann-La Roche
Phase 3
1,101
Aachen, Bad Homburg, Bayreuth, Bochum, Bremen, Erbach/Odenwald, Freiburg im Breisgau, Hamburg
2025-09-17
Recruiting
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
NCT07157774Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)
Eli Lilly and Company
Phase 3
10,450
Aachen, Bad Homburg, Berlin, Dresden, Essen, Frankfurt, Freiburg im Breisgau, Greifswald
2025-09-02
Recruiting
SCORE Study: Comparing Surgery and Rigid Collar Treatment for Odontoid Fractures in Adults Over 70
NCT06961578Odontoid Fracture, Elderly
Technical University of Munich
Not applicable
322
Munich, Frankfurt am Main, Berlin, Aachen, Cologne, Dresden, Essen, Göttingen
2025-08-13
Recruiting
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
NCT06963827Kidney Disease
DrugMezagitamab
Takeda
Phase 3
347
Aachen, Jena, Mainz
2025-07-15
Recruiting
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
NCT06976216Alzheimer's Disease
DrugsKarX-EC·KarXT
Bristol-Myers Squibb
Phase 3
586
Mannheim, Münster, Mainz, Berlin, Aachen, Bremen, Hamburg, Munich
2025-07-14
Recruiting
European Venous Registry
NCT06906250Deep Venous Disease of the Lower Limbs
IRCCS San Raffaele
Observational
100
Aachen
2025-07-05
Recruiting
Clinical Study on the Safety and Efficacy of the Minimally Invasive Ennovate® Method for Pedicle Screw Placement
NCT06960018Cervical Spine Disease, Pain, Postoperative
Aesculap AG
Not applicable
76
Aachen, Berlin, Freiburg im Breisgau
2025-06-20
Recruiting
Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation
NCT06717958AML, MDS
DrugIvosidenib
Technische Universität Dresden
Phase 2
76
Aachen, Chemnitz, Dresden, Erlangen, Essen, Frankfurt am Main, Greifswald, Halle
2025-06-17
Recruiting
A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia
NCT06953583Friedreich Ataxia
DrugsOmaveloxolone·Skyclarys
Biogen
Phase 3
255
Aachen, Giessen, Hamburg
2025-06-09
Recruiting
The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
NCT06872892Bronchiectasis
DrugVerducatib
Boehringer Ingelheim
Phase 3
1,755
Aachen, Ahrensburg, Bamberg, Berlin, Bochum, Bonn, Cologne, Donaustauf
2025-06-09
Active, closed
A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy
NCT06821542Chronic Graft-versus-host-disease
DrugAxatilimab
Incyte Corporation
Phase 3
9
Aachen, Berlin, Cologne, Dresden, Erlangen, Frankfurt am Main, Freiburg im Breisgau, Göttingen
2025-06-04
Recruiting
Assessing Declined Liver Grafts With Normothermic Machine Perfusion to Reduce Transplant Waiting Time
NCT06874296Liver Transplantation, Liver Diseases, Surgery
Charite University, Berlin, Germany
Not applicable
186
Hamburg, Aachen, Bonn, Münster, Berlin, Hanover, München, Regensburg
2025-06-02
Recruiting
Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)
NCT06904872Short Bowel Syndrome, Malabsorption Syndromes, Short Gut Syndrome, Post-Op Complication
DrugCrofelemer
Napo Therapeutics, S.p.A.
Phase 2
18
Aachen, Berlin, Essen, Hamburg, Rostock
2025-05-29
Recruiting
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
NCT06952504Endometrial Cancer
DrugsSacituzumab tirumotecan·Docetaxel·Paclitaxel·Cisplatin
Merck Sharp & Dohme LLC
Phase 3
1,123
Aachen, Trier, Saarbrücken, Leipzig, Jena, Berlin, Hamburg
2025-05-22
Recruiting
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
NCT06921785Hepatocellular Carcinoma
DrugsRilvegostomig·Tremelimumab·Atezolizumab·Bevacizumab
AstraZeneca
Phase 3
1,220
Aachen, Berlin, Bonn, Dortmund, Dresden, Essen, Frankfurt, Göttingen
2025-05-06
Recruiting
Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers
NCT06906341Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms, Endometrial Cancer
DrugsNab-paclitaxel /m^2·Relacorilant·Bevacizumab
Corcept Therapeutics
Phase 2
270
Aachen, Berlin, Kempten
2025-04-11
Active, closed
Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
NCT06858878Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
DrugMaridebart cafraglutide
Amgen
Phase 3
1,105
Aachen, Bad Krozingen, Bad Mergentheim, Bad Oeynhausen, Berlin, Elsterwerda, Essen, Falkensee
2025-03-17
Recruiting
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
NCT06677060Heart Failure
AstraZeneca
Phase 3
11,300
Aachen, Amberg, Bad Homburg, Bad Oeynhausen, Bamberg, Bechhofen, Berlin, Bochum
2025-03-14
Active, closed
Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
NCT06858839Obesity
DrugMaridebart cafraglutide
Amgen
Phase 3
3,853
Aachen, Bad Homburg, Bad Krozingen, Bad Mergentheim, Bad Oeynhausen, Berlin, Dresden, Elsterwerda
2025-03-12
Active, closed
Bemarituzumab in FGFR2b+ Patients With Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction, Who Failed at Least One Prior Line of Palliative Chemotherapy
NCT06680622Metastatic Gastro-esophageal Adenocarcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Phase 2
126
Aachen, Amberg, Augsburg, Bad Saarow, Berlin, Bielefeld, Chemnitz, Dortmund
2025-03-03
Recruiting
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
NCT06855498Hidradenitis Suppurativa (HS)
DrugPovorcitinib
Incyte Corporation
Phase 3
600
Aachen, Bad Bentheim, Berlin, Bochum, Bonn, Buxtehude, Darmstadt, Dortmund
2025-02-28
Recruiting
IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
NCT06713837Acute Myeloid Leukemia, Relapse/Recurrence
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Phase 3
339
Aachen, Greifswald, Halle, Rostock, Zwickau
2025-02-27
Recruiting
Tasquinimod in Patients with Myelofibrosis Refractory to or Intolerant for JAK2 Inhibition
NCT06605586Myelofibrosis
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 1/2
20
Aachen
2025-02-20
Recruiting
Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST Trial
NCT06456983Schizophrenia, Treatment Resistant Schizophrenia
Central Institute of Mental Health, Mannheim
Not applicable
140
Aachen, Augsburg, Göppingen, Göttingen, Hanover, Heidelberg, Ingolstadt, Mainz
2025-02-14
Recruiting
A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
NCT06686615Primary Hypercholesterolemiia, Mixed Dyslipidemia
DrugsBempedoic acid·Ezetimibe·Rosuvastatin·Atorvastatin
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Observational
2,000
Aachen, Ahaus, Alsfed, Bad Homburg, Berlin, Burg, Chemnitz, Detmold
2025-02-12
Recruiting
A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)
NCT06858579Chronic Inflammatory Demyelinating Polyneuropathy
DrugClaseprubart
Dianthus Therapeutics
Phase 3
256
München, Sande, Aachen, Greifswald, Rüdersdorf
2025-02-10
Recruiting
LEOPARD Training and Validation Data Collection Study
NCT06675604Decompensated Liver Cirrhosis, Primary Biliary Cholangitis, Primary Sclerosing Cholangitis, Hepato-cellular Carcinoma
Assistance Publique - Hôpitaux de Paris
Observational
4,500
Aachen, Berlin, Hanover, Jena, Kiel, Leipzig, Münster, Tübingen
2025-02-04
Recruiting
Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
NCT06487273Non-cystic Fibrosis Bronchiectasis
Physio-Assist
Not applicable
622
Aachen, Lübeck, München
2025-02-03
Recruiting
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
NCT06788990Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
DrugsFicerafusp alfa·Keytruda·Pembrolizumab
Bicara Therapeutics
Phase 2/3
650
Aachen, Berlin, Braunschweig, Chemnitz, Dresden, Düsseldorf, Essen, Göttingen
2025-01-28
Recruiting
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
NCT06585774Chronic Graft-versus-host-disease
DrugAxatilimab
Incyte Corporation
Phase 3
240
Aachen, Berlin, Bonn, Dresden, Düsseldorf, Erlangen, Essen, Halle
2025-01-21
Recruiting
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
NCT06712316Non-small Cell Lung Cancer
DrugsPumitamig·Pemetrexed·Paclitaxel·Carboplatin
BioNTech SE
Phase 2/3
1,580
Aachen, Berlin, Chemnitz, Düsseldorf, Erlangen, Esslingen am Neckar, Gauting, Gera
2025-01-07
Active, closed
Phase 2 Study of Rapcabtagene Autoleucel in Myositis
NCT06665256Idiopathic Inflammatory Myopathies
DrugRapcabtagene autoleucel
Novartis Pharmaceuticals
Phase 2
21
Cologne, Leipzig, Jena, Aachen, Hamburg, Mainz, Nuremberg, Ulm
2024-12-17
Recruiting
A Study to Learn More About the Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Who Are Prescribed it by Their Own Doctors
NCT06623890Friedreich Ataxia
DrugsOmaveloxolone·Skyclarys
Biogen
Observational
300
Tübingen, Aachen, Munich
2024-12-12
Recruiting
Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor
NCT06472245Patients With Non-Small Cell Lung Cancer
DrugsTedopi·Docetaxel
OSE Immunotherapeutics
Phase 3
363
Heidelberg, Stuttgart, Gauting, München, Kassel, Aachen, Bonn, Essen
2024-12-03
Active, closed
A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)
NCT06465329Non-Small Cell Lung Cancer
DrugsMarlotamig·Cemiplimab
Regeneron Pharmaceuticals
Phase 2
120
Kassel, Göttingen, Leipzig, Aachen
2024-11-18
Active, closed
Multinational Point Prevalence Study on the Management of Diabesity in Hospitals
NCT06680674Diabetes Mellitus, Obesity
Medical University of Vienna
Observational
400
Aachen
2024-11-13
Recruiting
A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study
NCT06531499Metastatic Castration-Resistant Prostate Cancer
DrugLu-PSMA
Novartis Pharmaceuticals
Phase 1
106
Cologne, Wuppertal, Aachen, Berlin, Essen, München, Rostock
2024-11-11
Recruiting
A Phase II Randomized, Open Label Non-inferiority Study of NiraParib Maintenance After 3 vs. 6 Cycles of Platinum-based Chemotherapy in completeLy debUlked Advanced HRDpositive High-grade Ovarian Cancer patientS in First Line Therapy
NCT05460000Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma, Clear Cell Carcinoma
North Eastern German Society of Gynaecological Oncology
Phase 2
640
Aachen, Baden-Baden, Berlin, Bonn, Cologne, Detmold, Dortmund, Dresden
2024-10-11
Active, closed
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)
NCT06516952Prurigo Nodularis
DrugPovorcitinib
Incyte Corporation
Phase 3
349
Aachen, Bad Bentheim, Berlin, Dortmund, Halle, Hamburg, Heidelberg, Leipzig
2024-10-10
Active, closed
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)
NCT06516965Prurigo Nodularis
DrugPovorcitinib
Incyte Corporation
Phase 3
346
Aachen, Buxtehude, Chemnitz, Darmstadt, Dresden, Frankfurt am Main, Göttingen, Magdeburg
2024-10-10
Recruiting
Abiomed Impella RT-DAQ - Observational Study
NCT06308055Cardiogenic Shock
Abiomed Inc.
Observational
125
Aachen, Kiel
2024-10-04
Recruiting
A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)
NCT06780150Multiple Sclerosis
DrugOcrelizumab
Hoffmann-La Roche
Observational
842
Aachen, Amberg, Arnsdorf, Aschaffenburg, Bad Soden, Bamberg, Berg, Berlin
2024-09-26
Recruiting
A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems
NCT06512454Alpha1-Antitrypsin Deficiency
Takeda
Observational
500
Aachen
2024-09-25
Recruiting
Efficacy and Safety of Oral Controlled-Ileocolonic-Release Nicotinamide (CICR-NAM) in Patients With Mild to Moderately Active Ulcerative Colitis
NCT06488625Ulcerative Colitis, Unspecified
University Hospital Schleswig-Holstein
Phase 2/3
459
Kiel, Aachen, Augsburg, Bamberg, Berlin, Bremen, Cologne, Dachau
2024-09-12
Active, closed
Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)
NCT06564142Immunoglobulin A Nephropathy
DrugPovetacicept
Alpine Immune Sciences Inc, A Subsidiary of Vertex
Phase 3
605
Aachen, Berlin, Dresden, Leipzig
2024-08-30
Active, closed
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
NCT06531824Kidney Disease, Chronic
DrugsVicadrostat·Dapagliflozin
Boehringer Ingelheim
Phase 3
11,000
Aachen, Bad Kreuznach, Bad Nenndorf, Bad Oeynhausen, Berlin, Bonn, Braunschweig, Coburg
2024-08-30
Recruiting
Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma
NCT06440993Extrahepatic Cholangiocarcinoma, Unresectable Perihilar or Ductal CCA
DrugsDurvalumab·Gemcitabine·Cisplatin
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Phase 2
42
Aachen, Bonn, Cologne, Düsseldorf, Frankfurt, Göttingen, Hanover, Lübeck
2024-08-23
Active, closed
A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms
NCT06313593Myeloproliferative Neoplasms
Incyte Corporation
Phase 1
37
Aachen, Essen, Halle
2024-08-08
Recruiting
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
NCT06380751Advanced Breast Cancer
DrugsSaruparib·Camizestrant·Exemestane·Anastrozole
AstraZeneca
Phase 3
788
Aachen, Augsburg, Berlin, Cologne, Dessau, Düsseldorf, Erlangen, Göttingen
2024-08-01
Active, closed
A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease
NCT06544616Alzheimer Disease
Janssen Pharmaceutica N.V., Belgium
Phase 2
55
Aachen, Cologne, Homburg, Münster
2024-07-22
Active, closed
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)
NCT06455202Chronic Spontaneous Urticaria
DrugBarzolvolimab
Celldex Therapeutics
Phase 3
976
Aachen, Bad Bentheim, Berlin, Bonn, Dresden, Düsseldorf, Essen, Hamburg
2024-07-19
Active, closed
A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD
NCT06405633Alpha-1 Antitrypsin Deficiency
Wave Life Sciences USA, Inc.
Phase 1/2
24
Aachen
2024-07-19
Active, closed
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
NCT06456346Essential Thrombocythemia
DrugsBomedemstat·Hydroxyurea
Merck Sharp & Dohme LLC
Phase 3
300
Landshut, Hanover, Aachen, Essen, Mainz, Halle, Jena, Berlin
2024-07-16
Recruiting
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
NCT05895136Liver Cirrhosis, Decompensated Cirrhosis of Liver, Acute on Chronic Liver Failure (ACLF)
DrugsHuman albumin·Enoxaparin
European Foundation for Study of Chronic Liver Failure
Phase 2
90
Aachen, Münster
2024-07-01
Recruiting
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
NCT06459024Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Observational
4,000
Aachen, Greifswald, Halle, Rostock
2024-06-28
Recruiting
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
NCT06465810Transthyretin Amyloidosis, ATTR-CM, ATTRv-PN, ATTR
AstraZeneca
Observational
1,850
Würzburg, Frankfurt am Main, Hanover, Aachen, Cologne, Mainz, Homburg, Berlin
2024-06-25
Recruiting
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
NCT06424288Heart Failure
DrugsVicadrostat·Dapagliflozin
Boehringer Ingelheim
Phase 3
6,712
Aachen, Bad Friedrichshall, Berlin, Bonn, Dessau, Dresden, Erfurt, Frankfurt
2024-06-17
Recruiting
Ultra-high-caloric, Fatty Diet in ALS
NCT06280079Amyotrophic Lateral Sclerosis
University of Ulm
Not applicable
392
Aachen, Berlin, Bochum, Bonn, Dresden, Erlangen, Essen, Göttingen
2024-06-01
Active, closed
A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis
NCT06294925Colitis, Ulcerative
DrugEtrasimod
Pfizer
Observational
360
Freiburg im Breisgau, Kassel, Aachen, Andernach, Berlin, Cologne, Dachau, Frankfurt am Main
2024-05-08
Active, closed
Real-world Study on Dapagliflozin Usage in Patients With Heart Failure (HF) in Germany
NCT06336330Heart Diseases, Cardiovascular Diseases, Heart Failure
AstraZeneca
Observational
831
Aachen, Alsfeld, Bamberg, Bechhofen, Bergisch Gladbach, Berlin, Brilon, Bruchsal
2024-04-25
Recruiting
Venetoclax Plus Azacitidine Versus Intensive Chemotherapy for Fit Patients With Newly Diagnosed NPM1 Mutated AML
NCT05904106Acute Myeloid Leukemia
DrugsGemtuzumab Ozogamicin·Azacitidine·Venetoclax
Technische Universität Dresden
Phase 2
146
Essen, Aachen, Augsburg, Chemnitz, Cologne, Dresden, Erlangen, Frankfurt am Main
2024-04-07
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 30 September 2026. https://priyalifescience.com/clinical-trials-germany/city/aachen

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,051 studies in total at the last sync on 26 Sep 2026, 19:51 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 267 of those studies with a site in Aachen.

How many clinical trials are recruiting in Aachen?

144 of the 267 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:51 UTC sync. A further 7 have not yet opened recruitment, 113 are active but closed to new participants, and 3 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Aachen), 267 studies
PhaseStudiesRecruitingShare
Phase 31115141.6%
Observational684725.5%
Phase 2371813.9%
Not applicable24109%
Phase 4833%
Phase 1/2762.6%
Phase 1642.2%
Phase 2/3652.2%

Most active sponsors

Lead sponsors with the most studies (Aachen)
Lead sponsorStudiesRecruiting
AstraZeneca188
RWTH Aachen University1413
Incyte Corporation104
Novartis Pharmaceuticals104
Hoffmann-La Roche73
Janssen Research & Development, LLC72
Technische Universität Dresden65
Merck Sharp & Dohme LLC51
Takeda54
Universitätsklinikum Hamburg-Eppendorf51
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.